Erschienen in:
01.09.2019 | Hot Topics in Pain and Headache (N Rosen, Section Editor)
Treatment Strategies and Effective Management of Phantom Limb–Associated Pain
verfasst von:
Ivan Urits, Danica Seifert, Allison Seats, Stephen Giacomazzi, Michael Kipp, Vwaire Orhurhu, Alan D. Kaye, Omar Viswanath
Erschienen in:
Current Pain and Headache Reports
|
Ausgabe 9/2019
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Abstract
Purpose of Review
Phantom sensations are incompletely understood phenomena which take place following an amputation or deafferentation of a limb. They can present as kinetic, kinesthetic, or exteroceptive perceptions. It is estimated that phantom limb pain (PLP) affects anywhere from 40 to 80% of amputees.
Recent Findings
Psychiatric illnesses such as depression, anxiety, and mood disorders have higher prevalence in amputees than in the general population. Pharmacologic treatment has been used as first-line therapy for amputees suffering from PLP with agents including gabapentinoids, amitriptyline, and other tricyclic anti-depressants, opioids, and local anesthetics. Non-invasive treatment modalities exist for PLP including sensory motor training, mirror visual therapy, and non-invasive neuromodulation. Non-invasive neuromodulation includes interventions like transcutaneous electrical nerve stimulation (TENS) and transcranial magnetic stimulation.
Summary
While many promising therapies for PLP exist, more clinical trials are required to determine the efficacy and protocols needed for maximum benefit in patients suffering from PLP.