Skip to main content
Erschienen in: Journal of Gastrointestinal Surgery 6/2018

15.02.2018 | Original Article

Unplanned Robotic-Assisted Conversion-to-Open Colorectal Surgery is Associated with Adverse Outcomes

verfasst von: Yongjin F. Lee, Jeremy Albright, Warqaa M. Akram, Juan Wu, Jane Ferraro, Robert K. Cleary

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 6/2018

Einloggen, um Zugang zu erhalten

Abstract

Background

Laparoscopic conversion-to-open colorectal surgery is associated with worse outcomes when compared to operations completed without conversion. Consequences of robotic conversion have not yet been determined. The purpose of this study is to compare short-term outcomes of converted robotic colorectal cases with those that are completed without conversion, as well as with cases done by the open approach.

Methods

The ACS-NSQIP database was queried for patients who underwent robotic completed, robotic converted-to-open, and open colorectal resection between 2012 and 2015. Propensity scores were estimated using gradient-boosted machines and converted to weights. Generalized linear models were fit using propensity score-weighted data.

Results

A total of 25,253 patients met inclusion criteria—21,356 (84.5%) open, 3663 (14.5%) robotic completed, and 234 (0.9%) conversions. Conversion rate was 6.0%. Converted cases had significantly higher 30-day mortality rate, higher complication rate, and longer hospital length of stay than completed cases. Converted patients also had significantly higher rates of the following complications: surgical site infections, cardiac complications, deep venous thrombosis, postoperative ileus, postoperative re-intubation, renal failure, and 30-day reoperation. Compared to the open approach, converted patients had significantly more cardiac complications, postoperative reintubation, and longer operating times with no significant difference in 30-day mortality.

Conclusions

Unplanned robotic conversion-to-open is associated with worse outcomes than completed cases and outcomes that more closely resemble traditional open colorectal surgery. Patients should be counseled with regard to minimally invasive conversion rates and outcomes. The continued pursuit of technological advancements that decrease the risk for conversion in minimally invasive colorectal surgery is clearly warranted.
Literatur
1.
Zurück zum Zitat Bhama AR, Wafa AM, Ferraro J, Collins SD, Mullard AJ, Vandewarker JF, Krapohl G, Byrn JC, Cleary RK. Comparison of risk factors for unplanned conversion from laparoscopic and robotic to open colorectal surgery using the Michigan Surgical Quality Collaborative (MSQC) Database. J Gastrointest Surg 2016 Jun;20(6):1223–1230.CrossRefPubMed Bhama AR, Wafa AM, Ferraro J, Collins SD, Mullard AJ, Vandewarker JF, Krapohl G, Byrn JC, Cleary RK. Comparison of risk factors for unplanned conversion from laparoscopic and robotic to open colorectal surgery using the Michigan Surgical Quality Collaborative (MSQC) Database. J Gastrointest Surg 2016 Jun;20(6):1223–1230.CrossRefPubMed
2.
Zurück zum Zitat Feinberg AE, Elnahas A, Bashir S, Cleghorn MC, Quereshy FA. Comparison of robotic and laparoscopic colorectal resections with respect to 30-day perioperative morbidity. Can J Surg 2016 Aug;59(4):262–267.CrossRefPubMedPubMedCentral Feinberg AE, Elnahas A, Bashir S, Cleghorn MC, Quereshy FA. Comparison of robotic and laparoscopic colorectal resections with respect to 30-day perioperative morbidity. Can J Surg 2016 Aug;59(4):262–267.CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Dolejs SC, Waters JA, Ceppa EP, Zarzaur BL. Laparoscopic versus robotic colectomy: a national surgical quality improvement project analysis. Surg Endosc. 2017;31:2387–2396CrossRefPubMed Dolejs SC, Waters JA, Ceppa EP, Zarzaur BL. Laparoscopic versus robotic colectomy: a national surgical quality improvement project analysis. Surg Endosc. 2017;31:2387–2396CrossRefPubMed
4.
Zurück zum Zitat Masoomi H, Moghadamyeghaneh Z, Mills S, Carmichael JC, Pigazzi A, Stamos MJ. Risk factors for conversion of laparoscopic colorectal surgery to open surgery: does conversion worsen outcome? World J Surg 2015 May;39(5):1240–1247.CrossRefPubMed Masoomi H, Moghadamyeghaneh Z, Mills S, Carmichael JC, Pigazzi A, Stamos MJ. Risk factors for conversion of laparoscopic colorectal surgery to open surgery: does conversion worsen outcome? World J Surg 2015 May;39(5):1240–1247.CrossRefPubMed
6.
Zurück zum Zitat Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM, Heath RM, Brown JM; UK MRC CLASICC Trial Group. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 2007 Jul 20;25(21):3061–3068.CrossRefPubMed Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM, Heath RM, Brown JM; UK MRC CLASICC Trial Group. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 2007 Jul 20;25(21):3061–3068.CrossRefPubMed
7.
Zurück zum Zitat Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, Heath RM, Brown JM, for the MRC CLASICC trial group. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 2005;365(9472):1718–1726.CrossRefPubMed Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AMH, Heath RM, Brown JM, for the MRC CLASICC trial group. Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 2005;365(9472):1718–1726.CrossRefPubMed
8.
Zurück zum Zitat Chan ACY, Poon JTC, Fan JK, Lo SH, Law WL. Impact of conversion on the long-term outcome in laparoscopic resection of colorectal cancer. Surg Endosc 2008;22:2625–2630.CrossRefPubMed Chan ACY, Poon JTC, Fan JK, Lo SH, Law WL. Impact of conversion on the long-term outcome in laparoscopic resection of colorectal cancer. Surg Endosc 2008;22:2625–2630.CrossRefPubMed
9.
Zurück zum Zitat Chew MH, Ng KH, Fook-Chong MC, Eu KW. Redefining conversion in laparoscopic colectomy and its influence on outcome analysis of 418 cases from a single institution. World J Surg 2011;35:178–185.CrossRefPubMed Chew MH, Ng KH, Fook-Chong MC, Eu KW. Redefining conversion in laparoscopic colectomy and its influence on outcome analysis of 418 cases from a single institution. World J Surg 2011;35:178–185.CrossRefPubMed
10.
Zurück zum Zitat Kang CY, Chaudhry OO, Halabi WJ, Nguyen V, Carmichael JC, Stamos MJ, Mills S. Outcomes of laparoscopic colorectal surgery: data from the Nationwide Inpatient Sample 2009. Am J Surg 2012 Dec;204(6):952–957.CrossRefPubMed Kang CY, Chaudhry OO, Halabi WJ, Nguyen V, Carmichael JC, Stamos MJ, Mills S. Outcomes of laparoscopic colorectal surgery: data from the Nationwide Inpatient Sample 2009. Am J Surg 2012 Dec;204(6):952–957.CrossRefPubMed
11.
Zurück zum Zitat Giglio MC, Luglio G, Sollazzo V, Liccardo F, Peltrini R, Sacco M, Spiezio G, Amato B, De Palma GD, Bucci L. Cancer recurrence following conversion during laparoscopic colorectal resections: a meta-analysis. Aging Clin Exp Res 2017;29 (Suppl 1):115–120.CrossRefPubMed Giglio MC, Luglio G, Sollazzo V, Liccardo F, Peltrini R, Sacco M, Spiezio G, Amato B, De Palma GD, Bucci L. Cancer recurrence following conversion during laparoscopic colorectal resections: a meta-analysis. Aging Clin Exp Res 2017;29 (Suppl 1):115–120.CrossRefPubMed
12.
Zurück zum Zitat Tam MS, Kaoutzanis C, Mullard AJ, Regenbogen SE, Franz MG, Hendren S, Krapohl G, Vandewarker JF, Lampman RM, Cleary RK. A population-based study comparing laparoscopic and robotic outcomes in colorectal surgery. Surg Endosc 2016 Feb;30(2):455–463.CrossRefPubMed Tam MS, Kaoutzanis C, Mullard AJ, Regenbogen SE, Franz MG, Hendren S, Krapohl G, Vandewarker JF, Lampman RM, Cleary RK. A population-based study comparing laparoscopic and robotic outcomes in colorectal surgery. Surg Endosc 2016 Feb;30(2):455–463.CrossRefPubMed
13.
Zurück zum Zitat Halabi WJ, Kang CY, Jafari MD, Nguyen VQ, Carmichael JC, Mills S, Stamos MJ, Pigazzi A. Robotic-assisted colorectal surgery in the United States: a nationwide analysis of trends and outcomes. World J Surg 2013 Dec;37(12):2782–2790.CrossRefPubMed Halabi WJ, Kang CY, Jafari MD, Nguyen VQ, Carmichael JC, Mills S, Stamos MJ, Pigazzi A. Robotic-assisted colorectal surgery in the United States: a nationwide analysis of trends and outcomes. World J Surg 2013 Dec;37(12):2782–2790.CrossRefPubMed
14.
Zurück zum Zitat McCaffrey DF, Griffin BA, Almirall D, Slaughter ME, Ramchand R, Burgette LF. A tutorial on propensity score estimation for multiple treatments using generalized boosted models. Stat Med 2013;32:3388–3414CrossRefPubMedPubMedCentral McCaffrey DF, Griffin BA, Almirall D, Slaughter ME, Ramchand R, Burgette LF. A tutorial on propensity score estimation for multiple treatments using generalized boosted models. Stat Med 2013;32:3388–3414CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Kolfschoten NE, van Leersum NJ, Gooiker GA, Marang van de Mheen PJ, Eddes EH, Kievit J, Brand R, Tanis PJ, Bemelman WA, Tollenaar RA, Meijerink J, Wouters MW. Successful and safe introduction of laparoscopic colorectal cancer surgery in Dutch hospitals. Ann Surg 2013 May;257(5):916–921.CrossRefPubMed Kolfschoten NE, van Leersum NJ, Gooiker GA, Marang van de Mheen PJ, Eddes EH, Kievit J, Brand R, Tanis PJ, Bemelman WA, Tollenaar RA, Meijerink J, Wouters MW. Successful and safe introduction of laparoscopic colorectal cancer surgery in Dutch hospitals. Ann Surg 2013 May;257(5):916–921.CrossRefPubMed
17.
Zurück zum Zitat Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM. Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 2013 Jan;100(1):75–82.CrossRefPubMed Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM. Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 2013 Jan;100(1):75–82.CrossRefPubMed
18.
Zurück zum Zitat Simorov A, Shaligram A, Shostrom V, Boilesen E, Thompson J, Oleynikov D. Laparoscopic colon resection trends in utilization and rate of conversion to open procedure: a national database review of academic medical centers. Ann Surg 2012;256(3):462–468.CrossRefPubMed Simorov A, Shaligram A, Shostrom V, Boilesen E, Thompson J, Oleynikov D. Laparoscopic colon resection trends in utilization and rate of conversion to open procedure: a national database review of academic medical centers. Ann Surg 2012;256(3):462–468.CrossRefPubMed
19.
Zurück zum Zitat Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M, Peters WR Jr, Maun D, Chang G, Herline A, Fichera A, Mutch M, Wexner S, Whiteford M, Marks J, Birnbaum E, Margolin D, Larson D, Marcello P, Posner M, Read T, Monson J, Wren SM, Pisters PW, Nelson H. Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes: the ACOSOG Z6051 randomized clinical trial. JAMA 2015 Oct 6;314(13):1346–1355.CrossRefPubMedPubMedCentral Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M, Peters WR Jr, Maun D, Chang G, Herline A, Fichera A, Mutch M, Wexner S, Whiteford M, Marks J, Birnbaum E, Margolin D, Larson D, Marcello P, Posner M, Read T, Monson J, Wren SM, Pisters PW, Nelson H. Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes: the ACOSOG Z6051 randomized clinical trial. JAMA 2015 Oct 6;314(13):1346–1355.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Belizon A, Sardinha CT, Sher ME. Converted laparoscopic colectomy: what are the consequences? Surg Endosc 2006 Jun;20(6):947–951.CrossRefPubMed Belizon A, Sardinha CT, Sher ME. Converted laparoscopic colectomy: what are the consequences? Surg Endosc 2006 Jun;20(6):947–951.CrossRefPubMed
21.
Zurück zum Zitat Franko J, Fassler SA, Rezvani M, O'Connell BG, Harper SG, Nejman JH, Zebley DM. Conversion of laparoscopic colon resection does not affect survival in colon cancer. Surg Endosc 2008 Dec;22(12):2631–2634.CrossRefPubMed Franko J, Fassler SA, Rezvani M, O'Connell BG, Harper SG, Nejman JH, Zebley DM. Conversion of laparoscopic colon resection does not affect survival in colon cancer. Surg Endosc 2008 Dec;22(12):2631–2634.CrossRefPubMed
22.
Zurück zum Zitat Lu KC, Cone MM, Diggs BS, Rea JD, Herzig DO. Laparoscopic converted to open colectomy: predictors and outcomes from the Nationwide Inpatient Sample. Am J Surg 2011 May;201(5):634–639.CrossRefPubMed Lu KC, Cone MM, Diggs BS, Rea JD, Herzig DO. Laparoscopic converted to open colectomy: predictors and outcomes from the Nationwide Inpatient Sample. Am J Surg 2011 May;201(5):634–639.CrossRefPubMed
23.
Zurück zum Zitat Agha A, Fürst A, Iesalnieks I, Fichtner-Feigl S, Ghali N, Krenz D, Anthuber M, Jauch KW, Piso P, Schlitt HJ. Conversion rate in 300 laparoscopic rectal resections and its influence on morbidity and oncological outcome. Int J Colorectal Dis 2008 Apr;23(4):409–417.CrossRefPubMed Agha A, Fürst A, Iesalnieks I, Fichtner-Feigl S, Ghali N, Krenz D, Anthuber M, Jauch KW, Piso P, Schlitt HJ. Conversion rate in 300 laparoscopic rectal resections and its influence on morbidity and oncological outcome. Int J Colorectal Dis 2008 Apr;23(4):409–417.CrossRefPubMed
24.
Zurück zum Zitat Ptok H, Kube R, Schmidt U, Köckerling F, Gastinger I, Lippert H, "Colon/Rectum Carcinoma (Primary Tumor)" Study Group. Conversion from laparoscopic to open colonic cancer resection—associated factors and their influence on long-term oncological outcome. Eur J Surg Oncol 2009 Dec;35(12):1273–1279. Ptok H, Kube R, Schmidt U, Köckerling F, Gastinger I, Lippert H, "Colon/Rectum Carcinoma (Primary Tumor)" Study Group. Conversion from laparoscopic to open colonic cancer resection—associated factors and their influence on long-term oncological outcome. Eur J Surg Oncol 2009 Dec;35(12):1273–1279.
25.
Zurück zum Zitat Yang C, Wexner SD, Safar B, Jobanputra S, Jin H, Li VK, Nogueras JJ, Weiss EG, Sands DR. Conversion in laparoscopic surgery: does intraoperative complication influence outcome? Surg Endosc 2009 Nov;23(11):2454–2458.CrossRefPubMed Yang C, Wexner SD, Safar B, Jobanputra S, Jin H, Li VK, Nogueras JJ, Weiss EG, Sands DR. Conversion in laparoscopic surgery: does intraoperative complication influence outcome? Surg Endosc 2009 Nov;23(11):2454–2458.CrossRefPubMed
26.
Zurück zum Zitat Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, Quirke P, West N, Rautio T, Thomassen N, Tilney H, Gudgeon M, Bianchi PP, Edlin R, Hulme C, Brown J. Effect of robotic-assisted conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA 2017;318(16):1569–1580CrossRefPubMedPubMedCentral Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, Quirke P, West N, Rautio T, Thomassen N, Tilney H, Gudgeon M, Bianchi PP, Edlin R, Hulme C, Brown J. Effect of robotic-assisted conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA 2017;318(16):1569–1580CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat van der Pas MHGM, Deijen CL, Abis GSA, de Lange-de Klerk, ESM, Haglind E, Fürst A, Lacy AM, Cuesta MA, Bonjer HJ, For the COLOR II study group. Conversions in laparoscopic surgery for rectal cancer. Surg Endosc 2017;31:2263–2270CrossRefPubMed van der Pas MHGM, Deijen CL, Abis GSA, de Lange-de Klerk, ESM, Haglind E, Fürst A, Lacy AM, Cuesta MA, Bonjer HJ, For the COLOR II study group. Conversions in laparoscopic surgery for rectal cancer. Surg Endosc 2017;31:2263–2270CrossRefPubMed
28.
Zurück zum Zitat Ricci C, Casadei R, Alagna V, Zani E, Taffurelli G, Pacillo CA, Minni F. A critical and comprehensive systematic review and meta-analysis of studies comparing intracorporeal and extracorporeal anastomosis in laparoscopic right hemicolectomy. Langenbecks Arch Surg 2016; https://doi.org/10.1007/s00423-016-1509 Ricci C, Casadei R, Alagna V, Zani E, Taffurelli G, Pacillo CA, Minni F. A critical and comprehensive systematic review and meta-analysis of studies comparing intracorporeal and extracorporeal anastomosis in laparoscopic right hemicolectomy. Langenbecks Arch Surg 2016; https://​doi.​org/​10.​1007/​s00423-016-1509
Metadaten
Titel
Unplanned Robotic-Assisted Conversion-to-Open Colorectal Surgery is Associated with Adverse Outcomes
verfasst von
Yongjin F. Lee
Jeremy Albright
Warqaa M. Akram
Juan Wu
Jane Ferraro
Robert K. Cleary
Publikationsdatum
15.02.2018
Verlag
Springer US
Erschienen in
Journal of Gastrointestinal Surgery / Ausgabe 6/2018
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI
https://doi.org/10.1007/s11605-018-3706-0

Weitere Artikel der Ausgabe 6/2018

Journal of Gastrointestinal Surgery 6/2018 Zur Ausgabe

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

23.04.2024 Ablationstherapie Nachrichten

Nach der Katheterablation von Vorhofflimmern kommt es bei etwa einem Drittel der Patienten zu Rezidiven, meist binnen eines Jahres. Wie sich spätere Rückfälle auf die Erfolgschancen einer erneuten Ablation auswirken, haben Schweizer Kardiologen erforscht.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

23.04.2024 Operationsvorbereitung Nachrichten

Derzeit wird empfohlen, eine Therapie mit GLP-1-Rezeptoragonisten präoperativ zu unterbrechen. Eine neue Studie nährt jedoch Zweifel an der Notwendigkeit der Maßnahme.

Ureterstriktur: Innovative OP-Technik bewährt sich

19.04.2024 EAU 2024 Kongressbericht

Die Ureterstriktur ist eine relativ seltene Komplikation, trotzdem bedarf sie einer differenzierten Versorgung. In komplexen Fällen wird dies durch die roboterassistierte OP-Technik gewährleistet. Erste Resultate ermutigen.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.