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01.12.2015 | Original Article

Use of gastrografin in the management of worm-induced small bowel obstruction in children

verfasst von: Raashid Hamid, Nisar Bhat, Aejaz Baba, Gowhar Mufti, Sheikh Khursheed, Sajad A. Wani, Imran Ali, Faheem Hassan

Erschienen in: Pediatric Surgery International | Ausgabe 12/2015

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Abstract

Objective

Ascaris-induced small bowel obstruction (SBO) is a common sequel of Ascaris lumbricoides (AL) infestation. Most cases respond to conservative treatment practiced in different centers worldwide. We conceived a prospective randomized trial to compare the conservative treatment with gastrografin administered in addition to the conservative treatment.

Study design

This prospective randomized study was conducted between January 2011 and June 2014 at Department of Paediatric and Neonatal Surgery, a tertiary-care hospital. Patients were divided into two groups, one group received conservative treatment and the other received gastrografin in addition to conservative treatment. Forty patients having uncomplicated AL-induced SBO were included in each group. Gastrografin was administered through nasogastric tube and serial clinical and radiological monitoring was performed. The duration of hospital stay, time between admission and first oral feed, passage of worms/flatus were compared in the two groups. Student’s t test was used for comparing these variables.

Results

Average time for passage of flatus or worms and resolution of abdominal signs and was shorter in gastrografin group as compared to the conservative group. This difference was found to be statistically significant. The average duration of hospital stay in gastrografin group was 25.20 ± 8.01 h whereas it was 61.12 ± 14.64 h in the conservative group (P < 0.001). The difference in the operation rate was statistically insignificant (2 in gastrografin group and 3 in the conservative group).No serious adverse reaction was noted after gastrografin administration.

Conclusion

Use of gastrografin resulted in faster relief of signs and symptoms of AL-induced SBO, early passage of worms/flatus and return to oral feeds. However, the role of gastrografin role in reducing the likelihood of laparotomy remains inconclusive. Adverse effects of gastrografin can be prevented if it is used in well-hydrated patients.

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Titel: Use of gastrografin in the management of worm-induced small bowel obstruction in children
verfasst von: Raashid Hamid
Nisar Bhat
Aejaz Baba
Gowhar Mufti
Sheikh Khursheed
Sajad A. Wani
Imran Ali
Faheem Hassan
Publikationsdatum: 01.12.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Surgery International / Ausgabe 12/2015
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-015-3793-x

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Use of gastrografin in the management of worm-induced small bowel obstruction in children