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01.08.2011 | Review | Ausgabe 4/2011

Breast Cancer Research 4/2011

Vitamin D and breast cancer: interpreting current evidence

Zeitschrift:
Breast Cancer Research > Ausgabe 4/2011
Autor:
Rowan T Chlebowski
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​bcr2846) contains supplementary material, which is available to authorized users.

Competing interests

The author declares that they have no competing interests.

Abstract

Preclinical investigations and selected clinical observational studies support an association between higher vitamin D intake and 25-hydroxyvitamin D levels with lower breast cancer risk. However, the recently updated report from the Institute of Medicine concluded that, for cancer and vitamin D, the evidence was 'inconsistent and insufficient to inform nutritional requirements'. Against this background, reports examining vitamin D intake, 25-hydroxyvitamin D levels and breast cancer incidence and outcome were reviewed. Current evidence supports the pursuit of several research questions but not routine 25-hydroxyvitamin D monitoring and vitamin D supplementation to reduce breast cancer incidence or improve breast cancer outcome.

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Zusatzmaterial
Authors’ original file for figure 1
13058_2011_2716_MOESM1_ESM.eps
Authors’ original file for figure 2
13058_2011_2716_MOESM2_ESM.pdf
Literatur
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