Erschienen in:
01.12.2014 | Editorial
A revival for immunoglobulin therapy in septic shock?
verfasst von:
Julien Textoris, Thierry Calandra, Frédéric Pène
Erschienen in:
Intensive Care Medicine
|
Ausgabe 12/2014
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Excerpt
As of 13 September 2014, World Sepsis Day, sepsis remains a leading cause of death worldwide. Over the last decade, the implementation of guidelines or bundles has had a major impact on the management of sepsis patients, stressing the need for prompt diagnosis and therapy including (1) early administration of antibiotics and source control, (2) hemodynamic resuscitation, and (3) prevention and management of organ failures. Besides antimicrobial therapy and supportive care, no immunomodulatory strategy has yielded clear-cut and reproducible results in terms of improved survival [
1]. …