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Erschienen in: Intensive Care Medicine 9/2019

25.07.2019 | Review

Acute ischaemic stroke: challenges for the intensivist

verfasst von: M. Smith, U. Reddy, C. Robba, D. Sharma, G. Citerio

Erschienen in: Intensive Care Medicine | Ausgabe 9/2019

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Abstract

Purpose

To provide an update about the rapidly developing changes in the critical care management of acute ischaemic stroke patients.

Methods

A narrative review was conducted in five general areas of acute ischaemic stroke management: reperfusion strategies, anesthesia for endovascular thrombectomy, intensive care unit management, intracranial complications, and ethical considerations.

Results

The introduction of effective reperfusion strategies, including IV thrombolysis and endovascular thrombectomy, has revolutionized the management of acute ischaemic stroke and transformed outcomes for patients. Acute therapeutic efforts are targeted to restoring blood flow to the ischaemic penumbra before irreversible tissue injury has occurred. To optimize patient outcomes, secondary insults, such as hypotension, hyperthermia, or hyperglycaemia, that can extend the penumbral area must also be prevented or corrected. The ICU management of acute ischaemic stroke patients, therefore, focuses on the optimization of systemic physiological homeostasis, management of intracranial complications, and neurological and haemodynamic monitoring after reperfusion therapies. Meticulous blood pressure management is of central importance in improving outcomes, particularly in patients that have undergone reperfusion therapies.

Conclusions

While consensus guidelines are available to guide clinical decision making after acute ischaemic stroke, there is limited high-quality evidence for many of the recommended interventions. However, a bundle of medical, endovascular, and surgical strategies, when applied in a timely and consistent manner, can improve long-term stroke outcomes.
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Metadaten
Titel
Acute ischaemic stroke: challenges for the intensivist
verfasst von
M. Smith
U. Reddy
C. Robba
D. Sharma
G. Citerio
Publikationsdatum
25.07.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 9/2019
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-019-05705-y

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