Skip to main content

Breast Cancer Research and Treatment

Ausgabe 3/2014

Inhalt (29 Artikel)

Review

The prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancer: a meta-analysis

Ezzeldin M. Ibrahim, Meteb E. Al-Foheidi, Mubarak M. Al-Mansour, Ghieth A. Kazkaz

Review

Metabolic isoenzyme shifts in cancer as potential novel therapeutic targets

S. N. Ononye, W. Shi, V. B. Wali, B. Aktas, T. Jiang, C. Hatzis, L. Pusztai

Preclinical study

A novel vaccinia virus with dual oncolytic and anti-angiogenic therapeutic effects against triple-negative breast cancer

Sepideh Gholami, Andrew Marano, Nanhai G. Chen, Richard J. Aguilar, Alexa Frentzen, Chun-Hao Chen, Emil Lou, Sho Fujisawa, Clarisse Eveno, Laurence Belin, Pat Zanzonico, Aladar Szalay, Yuman Fong

Preclinical Study

Natural history of tumor growth and immune modulation in common spontaneous murine mammary tumor models

Ekram Gad, Lauren Rastetter, Meredith Slota, Marlese Koehnlein, Piper M. Treuting, Yushe Dang, Sasha Stanton, Mary L. Disis

Open Access Preclinical study

Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study

D. Balmativola, C. Marchiò, M. Maule, L. Chiusa, L. Annaratone, F. Maletta, F. Montemurro, J. Kulka, P. Figueiredo, Z. Varga, I. Liepniece-Karele, G. Cserni, E. Arkoumani, I. Amendoeira, G. Callagy, A. Reiner-Concin, A. Cordoba, S. Bianchi, T. Decker, D. Gläser, C. Focke, P. van Diest, D. Grabau, E. Lips, J. Wesseling, R. Arisio, E. Medico, C. Wells, A. Sapino

Preclinical study

Tumor-infiltrating CD8+ and FOXP3+ lymphocytes in triple-negative breast cancer: its correlation with pathological complete response to neoadjuvant chemotherapy

Minoru Miyashita, Hironobu Sasano, Kentaro Tamaki, Monica Chan, Hisashi Hirakawa, Akihiko Suzuki, Hiroshi Tada, Go Watanabe, Noriko Nemoto, Saki Nakagawa, Takanori Ishida, Noriaki Ohuchi

Clinical Trial

Amrubicin as second- or third-line treatment for women with metastatic HER2-negative breast cancer: a Sarah Cannon Research Institute phase 1/2 trial

Denise A. Yardley, Eric Raefsky, John D. Hainsworth, Howard A. Burris III, Victor Priego, Alejandro Inclan

Clinical trial

Association between rim enhancement of breast cancer on dynamic contrast-enhanced MRI and patient outcome: impact of subtype

Alexander M. Th. Schmitz, Claudette E. Loo, Jelle Wesseling, Ruud M. Pijnappel, Kenneth G. A. Gilhuijs

Open Access Clinical trial

Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies

Chris Twelves, Javier Cortes, Linda Vahdat, Martin Olivo, Yi He, Peter A. Kaufman, Ahmad Awada

Open Access Clinical trial

Skin/nail infections with the addition of pertuzumab to trastuzumab-based chemotherapy

Joanne Mortimer, Jae Jung, Yuan Yuan, Laura Kruper, Daphne Stewart, Samuel Chung, Kim Wai Yu, Mary Mendelsohn, Massimo D’Apuzzo, Bernard Tegtmeier, Sanjeet Dadwal

Clinical trial

Pharmacogenomic diversity of tamoxifen metabolites and estrogen receptor genes in Hispanics and non-Hispanic whites with breast cancer

Leticia B. A. Rangel, Jodi L. Taraba, Christopher R. Frei, Lon Smith, Gladys Rodriguez, John G. Kuhn

Clinical Trial

NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer

C. Palmieri, S. Cleator, L. S. Kilburn, S. B. Kim, S.-H. Ahn, M. Beresford, G. Gong, J. Mansi, E. Mallon, S. Reed, K. Mousa, L. Fallowfield, M. Cheang, J. Morden, K. Page, D. S. Guttery, B. Rghebi, L. Primrose, J. A. Shaw, A. M. Thompson, J. M. Bliss, R. C. Coombes

Clinical Trial

Dose-dense paclitaxel versus docetaxel following FEC as adjuvant chemotherapy in axillary node-positive early breast cancer: a multicenter randomized study of the Hellenic Oncology Research Group (HORG)

Emmanouil Saloustros, Nikolaos Malamos, Ioannis Boukovinas, Stylianos Kakolyris, Charalampos Kouroussis, Athanasios Athanasiadis, Nikolaos Ziras, Nikolaos Kentepozidis, Parisis Makrantonakis, Aristidis Polyzos, Charalampos Christophyllakis, Vassilios Georgoulias, Dimitrios Mavroudis

Clinical trial

Gene expression profiling to predict the risk of locoregional recurrence in breast cancer: a pooled analysis

C. A. Drukker, S. G. Elias, M. V. Nijenhuis, J. Wesseling, H. Bartelink, P. Elkhuizen, B. Fowble, P. W. Whitworth, R. R. Patel, F. A. de Snoo, L. J. van ’t Veer, P. D. Beitsch, E. J. Th. Rutgers

Epidemiology

Methylation of the BRCA1 promoter in peripheral blood DNA is associated with triple-negative and medullary breast cancer

Satish Gupta, Katarzyna Jaworska-Bieniek, Steven A. Narod, Jan Lubinski, Tomasz K. Wojdacz, Jakubowska Anna

Epidemiology

Association of SULT1A1 Arg213His polymorphism with male breast cancer risk: results from a multicenter study in Italy

L. Ottini, P. Rizzolo, I. Zanna, V. Silvestri, C. Saieva, M. Falchetti, G. Masala, A. S. Navazio, C. Capalbo, S. Bianchi, S. Manoukian, M. Barile, P. Peterlongo, M. A. Caligo, L. Varesco, S. Tommasi, A. Russo, G. Giannini, L. Cortesi, G. Cini, M. Montagna, P. Radice, D. Palli

Epidemiology

Novel and recurrent BRCA2 mutations in Italian breast/ovarian cancer families widen the ovarian cancer cluster region boundaries to exons 13 and 14

Anna Coppa, Amelia Buffone, Carlo Capalbo, Arianna Nicolussi, Sonia D’Inzeo, Francesca Belardinilli, Valeria Colicchia, Marialaura Petroni, Teresa Granato, Cecilia Midulla, Massimo Zani, Sergio Ferraro, Isabella Screpanti, Alberto Gulino, Giuseppe Giannini

Epidemiology

Impact of histological subtype on long-term outcomes of neuroendocrine carcinoma of the breast

Jordan M. Cloyd, Rachel L. Yang, Kimberly H. Allison, Jeffrey A. Norton, Tina Hernandez-Boussard, Irene L. Wapnir

Epidemiology

Degree of urbanization and mammographic density in Dutch breast cancer screening participants: results from the EPIC-NL cohort

Marleen J. Emaus, Marije F. Bakker, Rob M. J. Beelen, Wouter B. Veldhuis, Petra H. M. Peeters, Carla H. van Gils

Epidemiology

Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer

Gianluca Severi, Melissa C. Southey, Dallas R. English, Chol-hee Jung, Andrew Lonie, Catriona McLean, Helen Tsimiklis, John L. Hopper, Graham G. Giles, Laura Baglietto

Brief Report

Breast cancer sensitivity to neoadjuvant therapy in BRCA1 and CHEK2 mutation carriers and non-carriers

Werner Pfeifer, Anna P. Sokolenko, Olga N. Potapova, Alexandr A. Bessonov, Alexandr O. Ivantsov, Sergey A. Laptiev, Olga A. Zaitseva, Olga S. Yatsuk, Dmitry E. Matsko, Tatiana Yu. Semiglazova, Alexandr V. Togo, Evgeny N. Imyanitov

Letter to the Editor

Concerns about methods for determination of estrogens in body fluids

Robert T. Chatterton, Miguel Muzzio, Peter H. Gann

Open Access Letter to the Editor

MRI screening of women with hereditary predisposition to breast cancer: diagnostic performance and survival analysis

Kukatharmini Tharmaratnam, Anne Irene Hagen, Pål Møller

Letter to the Editor

The frequency of the BLM p.Q548X (c.1642C>T) mutation in breast cancer patients from Russia is no higher than in the general population

Maksim S. Anisimenko, Anton E. Kozyakov, Galina A. Paul, Sergey P. Kovalenko

Rebuttal Letter

BCRT response to Moller

D. Gareth Evans

Rebuttal Letter

The frequency of the BLM*p.Q548X (c.1642C > T) mutation in breast cancer patients from Russia

Evgeny Imyanitov, Darya Prokofyeva, Natalia Bogdanova, Thilo Dörk

Erratum

Erratum to: Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours

Brigid C. Browne, Alex J. Eustace, Susan Kennedy, Neil A. O’Brien, Kasper Pedersen, Martina S. J. McDermott, Annemarie Larkin, Jo Ballot, Thamir Mahgoub, Francesco Sclafani, Stephen Madden, John Kennedy, Michael J. Duffy, John Crown, Norma O’Donovan

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.