Cancer Immunology, Immunotherapy

MDSC and beyond: a symposium-in-writing on myeloid cells with immunoregulatory activity by members of the Mye-EUNITER network

• Editorial

Sven Brandau

Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice

• Original Article

Elodie Pliquet, Claude Ruffie, Marie Escande, Jessie Thalmensi, Valérie Najburg, Chantal Combredet, Thomas Bestetti, Marion Julithe, Christelle Liard, Thierry Huet, Simon Wain-Hobson, Frédéric Tangy, Pierre Langlade-Demoyen

Adverse events need for hospitalization and systemic immunosuppression in very elderly patients (over 80 years) treated with ipilimumab for metastatic melanoma

• Original Article

Vaianu Leroy, Emilie Gerard, Caroline Dutriaux, Sorilla Prey, Aurelia Gey, Cécile Mertens, Marie Beylot-Barry, Anne Pham-Ledard

Immune checkpoint inhibitor-induced colitis as a predictor of survival in metastatic melanoma

• Original Article

Hamzah Abu-Sbeih, Faisal S. Ali, Wei Qiao, Yang Lu, Sapna Patel, Adi Diab, Yinghong Wang

Prognostic value of tumour-infiltrating CD8+ lymphocytes in rectal cancer after neoadjuvant chemoradiation: is indoleamine-2,3-dioxygenase (IDO1) a friend or foe?

• Original Article

Julia Schollbach, Stefan Kircher, Armin Wiegering, Florian Seyfried, Ingo Klein, Andreas Rosenwald, Christoph-Thomas Germer, Stefan Löb

A potential role for peripheral natural killer cell activity induced by preoperative chemotherapy in breast cancer patients

• Original Article

Ryungsa Kim, Ami Kawai, Megumi Wakisaka, Yuri Funaoka, Naomi Yasuda, Masayuki Hidaka, Yukitaka Morita, Shoichro Ohtani, Mitsuya Ito, Koji Arihiro

Mutations resulting in the formation of hyperactive complement convertases support cytocidal effect of anti-CD20 immunotherapeutics

• Open Access
• Original Article

Anna Felberg, Aleksandra Urban, Anna Borowska, Grzegorz Stasiłojć, Michał Taszner, Andrzej Hellmann, Anna Maria Blom, Marcin Okrój

The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma

• Clinical Trial Report

David Agdashian, Mei ElGindi, Changqing Xie, Milan Sandhu, Drew Pratt, David E. Kleiner, William D. Figg, Julie A. Rytlewski, Catherine Sanders, Erik C. Yusko, Bradford Wood, David Venzon, Gagandeep Brar, Austin G. Duffy, Tim F. Greten, Firouzeh Korangy

Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma

• Open Access
• Clinical Trial Report

Sandra P. D’Angelo, Matthias Hunger, Andrew S. Brohl, Paul Nghiem, Shailender Bhatia, Omid Hamid, Janice M. Mehnert, Patrick Terheyden, Kent C. Shih, Isaac Brownell, Céleste Lebbé, Karl D. Lewis, Gerald P. Linette, Michele Milella, Michael Schlichting, Meliessa H. Hennessy, Murtuza Bharmal

A pilot study of interferon-alpha-2b dose reduction in the adjuvant therapy of high-risk melanoma

• Open Access
• Clinical Trial Report

Lorena P. Suarez-Kelly, Kala M. Levine, Thomas E. Olencki, Sara E. Martin del Campo, Elizabeth A. Streacker, Taylor R. Brooks, Volodymyr I. Karpa, Joseph Markowitz, Anissa K. Bingman, Susan M. Geyer, Kari L. Kendra, William E. Carson

How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions

• Symposium-in-Writing Paper

Annika M. Bruger, Anca Dorhoi, Gunes Esendagli, Katarzyna Barczyk-Kahlert, Pierre van der Bruggen, Marie Lipoldova, Tomas Perecko, Juan Santibanez, Margarida Saraiva, Jo A. Van Ginderachter, Sven Brandau

Interactions among myeloid regulatory cells in cancer

• Symposium-in-Writing Paper

Viktor Umansky, Gosse J. Adema, Jaroslaw Baran, Sven Brandau, Jo A. Van Ginderachter, Xiaoying Hu, Jadwiga Jablonska, Slavko Mojsilovic, Helen A. Papadaki, Yago Pico de Coaña, Kim C. M. Santegoets, Juan F. Santibanez, Karine Serre, Yu Si, Isabela Sieminska, Maria Velegraki, Zvi G. Fridlender

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

• Open Access
• Symposium-in-Writing Paper

Giada Amodio, Joanna Cichy, Patricia Conde, Gianluca Matteoli, Aurélie Moreau, Jordi Ochando, Barbaros H. Oral, Michaela Pekarova, Elizabeth J. Ryan, Johannes Roth, Yahya Sohrabi, Maria-Cristina Cuturi, Silvia Gregori

MDSCs in infectious diseases: regulation, roles, and readjustment

• Symposium-in-Writing Paper

Anca Dorhoi, Estibaliz Glaría, Thalia Garcia-Tellez, Natalie E. Nieuwenhuizen, Gennadiy Zelinskyy, Benoit Favier, Anurag Singh, Jan Ehrchen, Cornelia Gujer, Christian Münz, Margarida Saraiva, Yahya Sohrabi, Ana E. Sousa, Peter Delputte, Michaela Müller-Trutwin, Annabel F. Valledor

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

• Open Access
• Symposium-in-Writing Paper

Luca Cassetta, Espen S. Baekkevold, Sven Brandau, Anna Bujko, Marco A. Cassatella, Anca Dorhoi, Carsten Krieg, Ang Lin, Karin Loré, Olivia Marini, Jeffrey W. Pollard, Mikael Roussel, Patrizia Scapini, Viktor Umansky, Gosse J. Adema

Acknowledgements

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