Erschienen in:
30.10.2023 | Research
Clinicopathological Features of Metastasis to the Oral and Maxillofacial Region—Multicenter Study
verfasst von:
Laura Borges Kirschnick, Lauren Frenzel Schuch, Rogério Gondak, Elena Riet Correa Rivero, Ana Paula Neutzling Gomes, Adriana Etges, Sandra Beatriz Chaves Tarquinio, Ricardo Alves Mesquita, Patrícia Carlos Caldeira, Adriana Aparecida Silva da Costa, Elismauro Francisco Mendonça, Jean Nunes dos Santos, Chané Smit, Liam Robinson, Elena María José Román Tager, Adalberto Mosqueda-Taylor, Hélder Antônio Rebelo Pontes, Bruno Augusto Benevenuto de Andrade, Thamyres Campos Fonseca, Aline Corrêa Abrahão, Michelle Agostini, Mário José Romañach, Fábio Abreu Alves, Graziella Chagas Jaguar, Nathalia Félix de Mendonça, Mariana Bitu Ramos Pinto, Luan César da Silva, Márcio Ajudarte Lopes, Pablo Agustin Vargas, Willie van Heerden, Lucas Guimarães Abreu, Manoela Domingues Martins, Ana Carolina Uchoa Vasconcelos
Erschienen in:
Head and Neck Pathology
|
Ausgabe 4/2023
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Abstract
Background
This study aimed to investigate the clinicopathological features of metastases in the oral and maxillofacial regions.
Methods
In this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.
Results
A total of 120 cases were evaluated. Of these, 53.78% affected female patients, with a mean age of 57.64 years. Intraosseous lesions were more frequent, particularly in the posterior region of the mandible (49.58%). Clinically, most cases presented with symptomatic swelling, with an average evolution time of 25 months. The clinical diagnostic hypothesis in most instances was that of a malignant lesion. Breast cancer was the most common primary tumor location in females, while lung origin was most common in males. In most cases, the primary cancer was an adenocarcinoma (44.73%). The follow-up period was available for 29 cases, and out of these, 20 had died due to the disease.
Conclusion
Although this is a rare condition, clinicians should be aware that any oral lesions have the possibility of being metastatic, particularly in individuals with a previous history of cancer. The findings from this study could assist clinicians in prompt diagnosing these lesions and subsequent conducting oncologic assessments and treatment.