Impact of intra-abdominal pressure on end-organ function. PANEL
A Pathophysiologic implications of increased intra-abdominal pressure on end-organ function within and outside the abdominal cavity. PANEL
B Clinical implications of increased intra-abdominal pressure at the bedside. Knowing IAP and understanding organ-organ crosstalk is key to adapt organ support therapy. Adapted with permission from Regli et al. according to the Open Access CC BY License 4.0 [
6].
AKI acute kidney injury,
APP abdominal perfusion pressure = MAP − IAP,
ΔIAP respiratory variation in IAP = IAPei − IAPee,
APV abdominal pressure variation = ΔIAP/(mean IAP),
Cab abdominal wall compliance,
Cdyn dynamic respiratory compliance,
CARS cardio-abdominal-renal-syndrome,
CO cardiac output,
CPP cerebral perfusion pressure,
CVP central venous pressure,
CVPtm transmural central venous pressure,
ECMO extracorporeal membrane oxygenation,
EN enteral nutrition,
EVLWI extravascular lung water index,
FG filtration gradient,
GEDVI global end-diastolic volume index,
GEF global ejection fraction,
GFR glomerular filtration rate,
GIPS global increased permeability syndrome,
GRV gastric residual volume,
HR heart rate,
IAP intra-abdominal pressure,
ICG-PDR indocyanine green plasma disappearance rate,
ICP intra-cranial pressure,
ITP intra-thoracic pressure,
MAP mean arterial pressure,
MMC migrating motor complex,
PAL combination of PEEP, albumin 20% and LASIX
® furosemide,
PEEP positive end-expiratory pressure,
PIP peak inspiratory pressure,
Paw airway pressures,
PCWP pulmonary capillary wedge pressure,
pHi intra-mucosal gastric pH,
PPV pulse pressure variation,
Qs/
Qt shunt fraction,
RM recruitment maneveur,
RVEDVI right ventricular end-diastolic volume index,
RVP renal venous pressure,
RVR renal vascular resistance,
SMA superior mesenteric artery,
SPV systolic pressure variation,
SVR systemic vascular resistance,
SVV stroke volume variation,
Vd/
Vt dead-space ventilation