Erschienen in:
01.09.2013 | Neuroanesthesia (JJ Pasternak, Section Editor)
Dexmedetomidine for Neurosurgical Procedures
verfasst von:
Adam Schwarz, Bobby Nossaman, Dominic Carollo, Usha Ramadhyani
Erschienen in:
Current Anesthesiology Reports
|
Ausgabe 3/2013
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Abstract
While earlier clinical investigations focused on characterizing the physiologic effects of dexmedetomidine and its role as a sedative drug in critically-ill patients, newer studies suggest that the alpha 2 adrenergic receptor agonist may have a role as an adjunct in intraoperative neuroanesthesia. Dexmedetomidine has been shown to have multiple favorable clinical effects such as lack of respiratory depression, neuroprotection, hemodynamic stability, and no apparent interference with intraoperative neurophysiologic monitoring. This suggests that dexmedetomidine can be useful in the management of neurosurgical patients.