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Erschienen in: Japanese Journal of Radiology 10/2019

01.08.2019 | Invited Review

Early detection of intrahepatic cholangiocarcinoma

verfasst von: Mami Hamaoka, Kazuto Kozaka, Osamu Matsui, Takahiro Komori, Takashi Matsubara, Norihide Yoneda, Kotaro Yoshida, Dai Inoue, Azusa Kitao, Wataru Koda, Toshifumi Gabata, Satoshi Kobayashi

Erschienen in: Japanese Journal of Radiology | Ausgabe 10/2019

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Abstract

Cholangiocarcinoma (CC) is a malignant tumor which arises from the biliary epithelium and most cases represent adenocarcinoma. CC can be classified into intrahepatic CC (ICC), perihilar CC, and distal CC, based on the site of anatomic origin. The incidence of ICC is increasing in both Western and Eastern countries, while that of extrahepatic cholangiocarcinoma remains fairly stable. ICC infiltrates into adjacent nerves and lymphatic vessels, resulting in progressive disease with a poor prognosis; thus, early detection of ICC is critical for achieving better outcomes and providing better patient care. However, it is difficult for clinicians to detect an ICC, especially in its early stage. Different from hepatocellular carcinoma, the lack of surveillance system for the high-risk group of CC does not allow for a reliable screening examination. In this context, for early detection and diagnosis of ICC, radiologists need to know predisposing conditions that can lead to the development of ICC, such as chronic biliary or hepatic inflammation, primary sclerosing cholangitis, congenital biliary diseases, and other conditions. In this article, we discuss and illustrate the radiologic features of ICC with special attention to early disease stages and of predisposing conditions of ICC.
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Metadaten
Titel
Early detection of intrahepatic cholangiocarcinoma
verfasst von
Mami Hamaoka
Kazuto Kozaka
Osamu Matsui
Takahiro Komori
Takashi Matsubara
Norihide Yoneda
Kotaro Yoshida
Dai Inoue
Azusa Kitao
Wataru Koda
Toshifumi Gabata
Satoshi Kobayashi
Publikationsdatum
01.08.2019
Verlag
Springer Japan
Erschienen in
Japanese Journal of Radiology / Ausgabe 10/2019
Print ISSN: 1867-1071
Elektronische ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-019-00860-0

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