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Erschienen in: Virchows Archiv 4/2007

01.04.2007 | Case Report

Expression of the breast differentiation antigen NY-BR-1 in a phyllodes tumor of the vulva

verfasst von: Olivier T. Giger, Elena Lacoste, Christoph Honegger, Barbara Padberg, Holger Moch, Zsuzsanna Varga

Erschienen in: Virchows Archiv | Ausgabe 4/2007

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Abstract

We describe a phyllodes tumor of borderline malignancy in the labium majus of a 49-year-old woman. The histogenetic origin of phyllodes tumors in the vulva is controversial. Strong immunoreactivity for NY-BR-1, a novel breast differentiation antigen, was demonstrated within the epithelial components of the phyllodes tumor. A similar expression pattern was observed in mammary-like glands of the vulva. These findings provide further evidence that phyllodes tumors of the vulva might derive from mammary-like glands in the labium majus or from ectopic breast tissue.
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Metadaten
Titel
Expression of the breast differentiation antigen NY-BR-1 in a phyllodes tumor of the vulva
verfasst von
Olivier T. Giger
Elena Lacoste
Christoph Honegger
Barbara Padberg
Holger Moch
Zsuzsanna Varga
Publikationsdatum
01.04.2007
Verlag
Springer-Verlag
Erschienen in
Virchows Archiv / Ausgabe 4/2007
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-007-0377-8

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