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Die Dermatologie
Erschienen in: Die Dermatologie 10/2018

14.09.2018 | Botulinumtoxin | CME

Hyperhidrose – Ätiopathogenese, Diagnostik, Klinik und Therapie

verfasst von: Prof. Dr. J. Wohlrab, B. Kreft

Erschienen in: Die Dermatologie | Ausgabe 10/2018

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Zusammenfassung

Die Hyperhidrose tritt meist als primäre, selten als sekundäre symptomatische Hyperhidrose auf. Die primäre Hyperhidrose wird als komplexe neuropathische Dysregulation mit genetischer Disposition verstanden, die ein pathologisches Schwitzverhalten mit vermehrter Schweißsekretion über mindestens 6 Monate bedingt und mindestens 4 der folgenden Diagnosekriterien erfüllt: Betroffenheit der Axillae und/oder der Handinnenflächen und/oder der Fußsohlen und/oder des Stirnbereiches, symmetrisches Auftreten, kein nächtliches Schwitzen, Häufigkeit des Auftretens mindestens wöchentlich, Beginn der Erkrankung vor dem 25. Lebensjahr, positive Familienanamnese sowie Beeinträchtigung der täglichen Aktivitäten. Zur Therapie der primären Hyperhidrose werden v. a. topisch Aluminiumsalze und Anticholinergika, Leitungswasseriontophorese sowie intrakutan Botulinumtoxin angewendet. In der systemischen Therapie kommen ebenfalls verschiedene Anticholinergika zum Einsatz. Meist als Ultima-Ratio-Therapie werden chirurgische Verfahren angewendet. Außerdem sind Verfahren zur Thermolyse entwickelt worden.
Literatur
1.
Murota H (2016) Sweating in systemic abnormalities: Uremia and diabetes mellitus. Curr Probl Dermatol 51:57–61PubMed
2.
Moraites E, Vaughn OA, Hill S (2014) Incidence and prevalence of hyperhidrosis. Dermatol Clin 32:457–465PubMed
3.
Semkova K, Gergovska M, Kazandjieva J et al (2015) Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. Clin Dermatol 33:483–491PubMed
4.
Bahar R, Zhou P, Liu Y et al (2016) The prevalence of anxiety and depression in patients with or without hyperhidrosis (HH). J Am Acad Dermatol 75:1126–1133PubMed
5.
Hamm H (2014) Impact of hyperhidrosis on quality of life and its assessment. Dermatol Clin 32:467–476PubMed
6.
Doolittle J, Walker P, Mills T et al (2016) Hyperhidrosis: An update on prevalence and severity in the United States. Arch Dermatol Res 308:743–749PubMedPubMedCentral
7.
Ricchetti-Masterson K, Symons JM, Aldridge M et al (2018) Epidemiology of hyperhidrosis in 2 population-based health care databases. J Am Acad Dermatol 78:358–362PubMed
8.
Lai FC, Tu YR, Li YP et al (2015) Nation wide epidemiological survey of primary palmar hyperhidrosis in the People’s Republic of China. Clin Auton Res 25:105–108PubMed
9.
Shayesteh A, Janlert U, Brulin C et al (2016) Prevalence and characteristics of Hyperhidrosis in Sweden: A cross-sectional study in the general population. Dermatology (Basel) 232:586–591
10.
Stefaniak T, Tomaszewski KA, Proczko-Markuszewska M et al (2013) Is subjective hyperhidrosis assessment sufficient enough? Prevalence of hyperhidrosis among young Polish adults. J Dermatol 40:819–823PubMed
11.
Liu Y, Bahar R, Kalia S et al (2016) Hyperhidrosis prevalence and demographical characteristics in dermatology outpatients in Shanghai and Vancouver. PLoS ONE 11:e153719PubMedPubMedCentral
12.
Estevan FA, Wolosker MB, Wolosker N et al (2017) Epidemiologic analysis of prevalence of the hyperhidrosis. An Bras Dermatol 92:630–634PubMedPubMedCentral
13.
Feldmeyer L, Bogdan I, Moser A et al (2015) Short- and long-term efficacy and mechanism of action of tumescent suction curettage for axillary hyperhidrosis. J Eur Acad Dermatol Venereol 29:1933–1937PubMed
14.
Lee JB, Kim JH, Murota H (2016) Perspiration functions in different ethnic, Age, and sex populations: Modification of sudomotor function. Curr Probl Dermatol 51:109–119PubMed
15.
Augustin M, Radtke MA, Herberger K et al (2013) Prevalence and disease burden of hyperhidrosis in the adult population. Dermatology (Basel) 227:10–13
16.
Fujimoto T (2016) Pathophysiology and treatment of hyperhidrosis. Curr Probl Dermatol 51:86–93PubMed
17.
Ro KM, Cantor RM, Lange KL et al (2002) Palmar hyperhidrosis: Evidence of genetic transmission. J Vasc Surg 35:382–386PubMed
18.
Karimian-Teherani D, Panhofer P, Ringhofer C et al (2009) New epidemiological aspects of patients with severe hyperhidrosis presenting for sympathetic surgery. J Eur Acad Dermatol Venereol 23:651–655PubMed
19.
Kaufmann H, Saadia D, Polin C et al (2003) Primary hyperhidrosis—evidence for autosomal dominant inheritance. Clin Auton Res 13:96–98PubMed
20.
Lima SO, Aragao JF, Machado Neto J et al (2015) Research of primary hyperhidrosis in students of medicine of the state of Sergipe, Brazil. An Bras Dermatol 90:661–665PubMedPubMedCentral
21.
Chen J, Lin M, Chen X et al (2015) A novel locus for primary focal hyperhidrosis mapped on chromosome 2q31.1. Br J Dermatol 172:1150–1153PubMed
22.
Higashimoto I, Yoshiura K, Hirakawa N et al (2006) Primary palmar hyperhidrosis locus maps to 14q11.2-q13. Am J Med Genet A 140:567–572PubMed
23.
Groscurth P (2002) Anatomy of sweat glands. Curr Probl Dermatol 30:1–9PubMed
24.
Ito T (1988) Morphological connections of the human apocrine and eccrine sweat gland—occurrence of the so-called “mixed sweat glands”—a review. Okajimas Folia Anat Jpn 65:315–335PubMed
25.
Wilke K, Martin A, Terstegen L et al (2007) A short history of sweat gland biology. Int J Cosmet Sci 29:169–179PubMed
26.
Birner P, Heinzl H, Schindl M et al (2000) Cardiac autonomic function in patients suffering from primary focal hyperhidrosis. Eur Neurol 44:112–116PubMed
27.
De Marinis M, Colaizzo E, Petrelli RA et al (2012) Alterations in cardiovascular autonomic function tests in idiopathic hyperhidrosis. Auton Neurosci 167:34–38PubMed
28.
Iwase S, Ikeda T, Kitazawa H et al (1997) Altered response in cutaneous sympathetic outflow to mental and thermal stimuli in primary palmoplantar hyperhidrosis. J Auton Nerv Syst 64:65–73PubMed
29.
Lin TK, Chee EC, Chen HJ et al (1995) Abnormal sympathetic skin response in patients with palmar hyperhidrosis. Muscle Nerve 18:917–919PubMed
30.
De Lima AG, Das-Neves-Pereira JC, De Campos JR et al (2011) Factors affecting long-term satisfaction after thoracic sympathectomy for palmar and plantar hyperhidrosis. Is the sudomotor reflex the only villain? Interact Cardiovasc Thorac Surg 12:554–557PubMed
31.
Janig W (1985) Organization of the lumbar sympathetic outflow to skeletal muscle and skin of the cat hindlimb and tail. Rev Physiol Biochem Pharmacol 102:119–213PubMed
32.
Macefield VG, Sverrisdottir YB, Elam M et al (2008) Firing properties of sudomotor neurones in hyperhidrosis and thermal sweating. Clin Auton Res 18:325–330PubMed
33.
Noppen M, Sevens C, Vincken WG (1997) Effects of non-pharmacological sympathetic sudomotor denervation on sweating in humans with essential palmar hyperhidrosis. Clin Biochem 30:171–175PubMed
34.
Manca D, Valls-Sole J, Callejas MA (2000) Excitability recovery curve of the sympathetic skin response in healthy volunteers and patients with palmar hyperhidrosis. Clin Neurophysiol 111:1767–1770PubMed
35.
Schestatsky P, Callejas MA, Valls-Sole J (2011) Abnormal modulation of electrodermal activity by thermoalgesic stimuli in patients with primary palmar hyperhidrosis. J Neurol Neurosurg Psychiatr 82:92–96
36.
Ak M, Dincer D, Haciomeroglu B et al (2013) Temperament and character properties of primary focal hyperhidrosis patients. Health Qual Life Outcomes 11:5PubMedPubMedCentral
37.
Karaca S, Emul M, Kulac M et al (2007) Temperament and character profile in patients with essential hyperhidrosis. Dermatology (Basel) 214:240–245
38.
De Moura Júnior NB, Das-Neves-Pereira JC, De Oliveira FR et al (2013) Expression of acetylcholine and its receptor in human sympathetic ganglia in primary hyperhidrosis. Ann Thorac Surg 95:465–470PubMed
39.
Karaca S, Kulac M, Uz E et al (2006) Erythrocyte oxidant/antioxidant status in essential hyperhidrosis. Mol Cell Biochem 290:131–135PubMed
40.
Karaca S, Kulac M, Uz E et al (2007) Is nitric oxide involved in the pathophysiology of essential hyperhidrosis? Int J Dermatol 46:1027–1030PubMed
41.
Moya J, Ramos R, Prat J et al (2003) Histopathological changes in sympathetic ganglia of patients treated surgically for palmar-axillary hyperhidrosis. A study of 55 biopsies. Arch Bronconeumol 39:115–117PubMed
42.
Walling HW (2011) Clinical differentiation of primary from secondary hyperhidrosis. J Am Acad Dermatol 64:690–695PubMed
43.
Hornberger J, Grimes K, Naumann M et al (2004) Recognition, diagnosis, and treatment of primary focal hyperhidrosis. J Am Acad Dermatol 51:274–286PubMed
44.
Thomas I, Brown J, Vafaie J et al (2004) Palmoplantar hyperhidrosis: a therapeutic challenge. Am Fam Physician 69:1117–1120PubMed
45.
46.
Murota H (2016) Old and new approaches for assessing sweating. Curr Probl Dermatol 51:22–29PubMed
47.
Skroza N, Bernardini N, La Torre G et al (2011) Correlation between dermatology life quality index and minor test and differences in their levels over time in patients with axillary hyperhidrosis treated with botulinum toxin type A. Acta Dermatovenerol Croat 19:16–20PubMed
48.
Sarkany I, Gaylarde PM (1972) Letters to the editor. A silicon rubber technique to demonstrate sweat gland activity. J Invest Dermatol 59:269PubMed
49.
Lee J, Pyo M, Lee SH et al (2014) Hydrochromic conjugated polymers for human sweat pore mapping. Nat Commun 5:3736PubMed
50.
Elsner C, Abel B (2014) Ultrafast high-resolution mass spectrometric finger pore imaging in latent finger prints. Sci Rep 4:6905PubMedPubMedCentral
51.
Heckmann M, Breit S, Ceballos-Baumann A et al (1999) Side-controlled intradermal injection of botulinum toxin A in recalcitrant axillary hyperhidrosis. J Am Acad Dermatol 41:987–990PubMed
52.
Stefaniak TJ, Proczko M (2013) Gravimetry in sweating assessment in primary hyperhidrosis and healthy individuals. Clin Auton Res 23:197–200PubMedPubMedCentral
53.
Hund M, Kinkelin I, Naumann M et al (2002) Definition of axillary hyperhidrosis by gravimetric assessment. Arch Dermatol 138:539–541PubMed
54.
Matsui S, Murota H, Takahashi A et al (2014) Dynamic analysis of histamine-mediated attenuation of acetylcholine-induced sweating via GSK3beta activation. J Invest Dermatol 134:326–334PubMed
55.
Ohmi M, Tanigawa M, Wada Y et al (2012) Dynamic analysis for mental sweating of a group of eccrine sweat glands on a human fingertip by optical coherence tomography. Skin Res Technol 18:378–383PubMed
56.
Ohmi M, Tanigawa M, Yamada A et al (2009) Dynamic analysis of internal and external mental sweating by optical coherence tomography. J Biomed Opt 14:14026PubMed
57.
Masters BR, So PT, Gratton E (1998) Multiphoton excitation microscopy of in vivo human skin. Functional and morphological optical biopsy based on three-dimensional imaging, lifetime measurements and fluorescence spectroscopy. Ann N Y Acad Sci 838:58–67PubMed
58.
Worle B, Rapprich S, Heckmann M (2007) Definition and treatment of primary hyperhidrosis. J Dtsch Dermatol Ges 5:625–628PubMed
59.
Schlereth T, Dieterich M, Birklein F (2009) Hyperhidrosis–causes and treatment of enhanced sweating. Dtsch Arztebl Int 106:32–37PubMedPubMedCentral
60.
Strutton DR, Kowalski JW, Glaser DA et al (2004) US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: Results from a national survey. J Am Acad Dermatol 51:241–248PubMed
61.
Baez A, Paleari J, Duran MN et al (2007) Frey syndrome secondary to submaxillectomy and botulinic treatment. Medicina (B Aires) 67:478–480
62.
Kim JM, Seo SD, Kim YW et al (2014) Contralateral hyperhidrosis in anterior thalamic infarction. Clin Auton Res 24:311–313PubMed
63.
Layton J (2005) A review of harlequin ichthyosis. Neonatal Netw 24:17–23PubMed
64.
Gitter DG, Sato K (1990) Localized hyperhidrosis in pretibial myxedema. J Am Acad Dermatol 23:250–254PubMed
65.
Ruiz De Erenchun F, Vazquez-Doval FJ, Contreras Mejuto F et al (1992) Localized unilateral hyperhidrosis: Eccrine nevus. J Am Acad Dermatol 27:115–116PubMed
66.
67.
Solish N, Bertucci V, Dansereau A et al (2007) A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis: Recommendations of the Canadian Hyperhidrosis Advisory Committee. Dermatol Surg 33:908–923PubMed
68.
Bechara FG, Sand M, Sand D et al (2007) Suction-curettage as a surgical treatment of focal axillary hyperhidrosis: Recommendation for an aggressive approach. Plast Reconstr Surg 119:1390–1391PubMed
69.
Glaser DA, Hebert AA, Pariser DM et al (2007) Facial hyperhidrosis: Best practice recommendations and special considerations. Cutis 79:29–32PubMed
70.
Glaser DA, Hebert AA, Pariser DM et al (2007) Palmar and plantar hyperhidrosis: Best practice recommendations and special considerations. Cutis 79:18–28PubMed
71.
Kamudoni P, Mueller B, Halford J et al (2017) The impact of hyperhidrosis on patients’ daily life and quality of life: A qualitative investigation. Health Qual Life Outcomes 15:121PubMedPubMedCentral
72.
Lessa Lda R, Luz FB, De Rezende RM et al (2014) The psychiatric facet of hyperhidrosis: Demographics, disability, quality of life, and associated psychopathology. J Psychiatr Pract 20:316–323PubMed
73.
74.
Innocenzi D, Ruggero A, Francesconi L et al (2008) An open-label tolerability and efficacy study of an aluminum sesquichlorohydrate topical foam in axillary and palmar primary hyperhidrosis. Dermatol Ther 21(Suppl 1):27–30
75.
Streker M, Kerscher M (2012) Antiperspirants for the therapy of focal hyperhidrosis. Hautarzt 63:452–455PubMed
76.
Hölzle E, Braun-Falco O (1984) Structural changes in axillary eccrine glands following long-term treatment with aluminium chloride hexahydrate solution. Br J Dermatol 110:399–403PubMed
77.
78.
Bergstresser PR, Quero R (1976) Treatment of hyperhidrosis with topical methenamine. Int J Dermatol 15:452–455PubMed
79.
Cullen SI (1975) Topical methenamine therapy for hyperhidrosis. Arch Dermatol 111:1158–1160PubMed
80.
Sega-Hall GM, Smith P, Haworth AE (2006) A case of isolated axillary hyperhidrosis successfully treated topically with 1 % glycopyrronium cream. Clin Exp Dermatol 31:825PubMed
81.
82.
Artzi O, Loizides C, Zur E et al (2017) Topical oxybutynin 10 % gel for the treatment of primary focal hyperhidrosis: A randomized double-blind placebo-controlled split area study. Acta Derm Venereol 97:1120–1124PubMed
83.
Nasir A, Bissonnette R, Maari C et al (2018) A phase 2a randomized controlled study to evaluate the pharmacokinetic, safety, tolerability and clinical effect of topically applied Umeclidinium in subjects with primary axillary hyperhidrosis. J Eur Acad Dermatol Venereol 32:145–151PubMed
84.
Glogau RG (2007) Topically applied botulinum toxin type A for the treatment of primary axillary hyperhidrosis: results of a randomized, blinded, vehicle-controlled study. Dermatol Surg 33:S76–S80PubMed
85.
86.
Hosp C, Naumann MK, Hamm H (2012) Botulinum toxin in focal hyperhidrosis. An update. Hautarzt 63:469–476PubMed
87.
Rosen R, Stewart T (2018) Results of a 10-year follow-up study of botulinum toxin A therapy for primary axillary hyperhidrosis in Australia. Intern Med J 48:343–347PubMed
88.
Grunfeld A, Murray CA, Solish N (2009) Botulinum toxin for hyperhidrosis: A review. Am J Clin Dermatol 10:87–102PubMed
89.
Baumann L, Slezinger A, Halem M et al (2005) Double-blind, randomized, placebo-controlled pilot study of the safety and efficacy of Myobloc (botulinum toxin type B) for the treatment of palmar hyperhidrosis. Dermatol Surg 31:263–270PubMed
90.
Baumann L, Slezinger A, Halem M et al (2005) Pilot study of the safety and efficacy of Myobloc (botulinum toxin type B) for treatment of axillary hyperhidrosis. Int J Dermatol 44:418–424PubMed
91.
Frasson E, Brigo F, Acler M et al (2011) Botulinum toxin type A vs type B for axillary hyperhidrosis in a case series of patients observed for 6 months. Arch Dermatol 147:122–123PubMed
92.
Bergon-Sendin M, Pulido-Perez A, Saez-Martin LC et al (2016) Preliminary experience with transdermal oxybutynin patches for hyperhidrosis. Actas Dermosifiliogr 107:845–850PubMed
93.
Millan-Cayetano JF, Del Boz J, Toledo-Pastrana T et al (2017) Initial study of transdermal oxybutynin for treating hyperhidrosis. J Dermatol 44:717–720PubMed
94.
Van Der Maaden K, Jiskoot W, Bouwstra J (2012) Microneedle technologies for (trans)dermal drug and vaccine delivery. J Control Release 161:645–655
95.
Castells Rodellas A, Moragon Gordon M, Ramirez Bosca A (1987) Effect of bornaprine in localized hyperhidrosis. Med Cutan Ibero Lat Am 15:303–305PubMed
96.
Sergi R, Massone A, Moretto S et al (2008) Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients. Spinal Cord 46:571–573PubMed
97.
Muller C, Berensmeier A, Hamm H et al (2013) Efficacy and safety of methantheline bromide (Vagantin) in axillary and palmar hyperhidrosis: Results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol 27:1278–1284PubMed
98.
Del Boz J, Millan-Cayetano JF, Rivas-Ruiz F et al (2017) Oral glycopyrrolate after the failure of oral oxybutynin in the treatment of primary hyperhidrosis. Br J Dermatol 176:821–823PubMed
99.
Del Boz J, Millan-Cayetano JF, Blazquez-Sanchez N et al (2016) Individualized dosing of oral oxybutynin for the treatment of primary focal hyperhidrosis in children and teenagers. Pediatr Dermatol 33:327–331PubMed
100.
101.
Delort S, Marchi E, Correa MA (2017) Oxybutynin as an alternative treatment for hyperhidrosis. An Bras Dermatol 92:217–220PubMedPubMedCentral
102.
Cruddas L, Baker DM (2017) Treatment of primary hyperhidrosis with oral anticholinergic medications: A systematic review. J Eur Acad Dermatol Venereol 31:952–963PubMed
103.
Walling HW (2012) Systemic therapy for primary hyperhidrosis: A retrospective study of 59 patients treated with glycopyrrolate or clonidine. J Am Acad Dermatol 66:387–392PubMed
104.
Kim DH, Kim TH, Lee SH et al (2017) Treatment of palmar hyperhidrosis with tap water Iontophoresis: A randomized, sham-controlled, single-blind, and parallel-designed clinical trial. Ann Dermatol 29:728–734PubMedPubMedCentral
105.
Pariser DM, Ballard A (2014) Iontophoresis for palmar and plantar hyperhidrosis. Dermatol Clin 32:491–494PubMed
106.
Thomas L, Fatah S, Carmichael AJ (2015) Tap water iontophoresis may be ineffective for axillary hyperhidrosis. Clin Exp Dermatol 40:337–338PubMed
107.
Leow MQH, Tey HL (2017) Treatment of primary palmar hyperhidrosis using glycopyrrolate iontophoresis: Intensity of electrical current used, efficacy and side effects. Indian J Dermatol Venereol Leprol 83:387–388PubMed
108.
Cervantes J, Perper M, Eber AE et al (2018) Laser treatment of primary axillary hyperhidrosis: A review of the literature. Lasers Med Sci 33:675–681PubMed
109.
Mordon S, Plot E (2009) Laser lipolysis versus traditional liposuction for fat removal. Expert Rev Med Devices 6:677–688PubMed
110.
Nestor MS, Park H (2014) Safety and efficacy of micro-focused ultrasound plus visualization for the treatment of axillary hyperhidrosis. J Clin Aesthet Dermatol 7:14–21PubMedPubMedCentral
111.
Glaser DA, Coleman WP 3rd, Fan LK et al (2012) A randomized, blinded clinical evaluation of a novel microwave device for treating axillary hyperhidrosis: The dermatologic reduction in underarm perspiration study. Dermatol Surg 38:185–191PubMed
112.
Abtahi-Naeini B, Naeini FF, Adibi N et al (2015) Quality of life in patients with primary axillary hyperhidrosis before and after treatment with fractionated microneedle radiofrequency. J Res Med Sci 20:631–635PubMedPubMedCentral
113.
Salah M, Attia A (2011) New topical photodynamic therapy for management of primary axillary hyperhidrosis: A single-blinded, placebo-controlled study. J Egypt Women Dermatol 8:36–42
114.
Darabaneanu S, Darabaneanu HA, Niederberger U et al (2008) Long-term efficacy of subcutaneous sweat gland suction curettage for axillary hyperhidrosis: A prospective gravimetrically controlled study. Dermatol Surg 34:1170–1177PubMed
115.
Lyra Rde M, Campos JR, Kang DW et al (2008) Guidelines for the prevention, diagnosis and treatment of compensatory hyperhidrosis. J Bras Pneumol 34:967–977PubMed
116.
Lawrence CM, Lonsdale Eccles AA (2006) Selective sweat gland removal with minimal skin excision in the treatment of axillary hyperhidrosis: A retrospective clinical and histological review of 15 patients. Br J Dermatol 155:115–118PubMed
117.
Hussain AB, Holme SA, Kavanagh GM (2016) Shelley procedure in axillary hyperhidrosis. Clin Exp Dermatol 41:229–231PubMed
118.
Wollina U, Köstler E, Schönlebe J et al (2008) Tumescent suction curettage versus minimal skin resection with subcutaneous curettage of sweat glands in axillary hyperhidrosis. Dermatol Surg 34:709–716PubMed
119.
De Andrade Filho LO, Kuzniec S, Wolosker N et al (2013) Technical difficulties and complications of sympathectomy in the treatment of hyperhidrosis: An analysis of 1731 cases. Ann Vasc Surg 27:447–453PubMed
120.
Zhang W, Yu D, Wei Y et al (2017) A systematic review and meta-analysis of T2, T3 or T4, to evaluate the best denervation level for palmar hyperhidrosis. Sci Rep 7:129PubMedPubMedCentral
121.
Atkinson JL, Fode-Thomas NC, Fealey RD et al (2011) Endoscopic transthoracic limited sympathotomy for palmar-plantar hyperhidrosis: Outcomes and complications during a 10-year period. Mayo Clin Proc 86:721–729PubMedPubMedCentral
Metadaten
Titel
Hyperhidrose – Ätiopathogenese, Diagnostik, Klinik und Therapie
verfasst von
Prof. Dr. J. Wohlrab
B. Kreft
Publikationsdatum
14.09.2018
Verlag
Springer Medizin
Erschienen in
Die Dermatologie / Ausgabe 10/2018
Print ISSN: 2731-7005
Elektronische ISSN: 2731-7013
DOI
https://doi.org/10.1007/s00105-018-4265-8

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Den Reflex, eine oberflächliche chronische Hautwunde ohne Entzündungszeichen in jedem Fall abzustreichen, sollte man nach einer neuen „Klug-entscheiden“-Empfehlung unterdrücken.

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