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Skeletal Radiology

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20.10.2018 | Technical Report

Initial experience with dual-energy computed tomography-guided bone biopsies of bone lesions that are occult on monoenergetic CT

verfasst von: Michael C. Burke, Ankur Garg, Jonathan M. Youngner, Swati D. Deshmukh, Imran M. Omar

Erschienen in: Skeletal Radiology | Ausgabe 4/2019

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Abstract

Objective

Our purpose was to determine whether dual-energy CT (DECT), specifically the bone marrow setting of the virtual noncalcium (VNCa) algorithm, could be used to identify and accurately biopsy suspected bone malignancies that were visible on magnetic resonance imaging (MRI), nuclear bone scintigraphy, or positron-emission tomography/computed tomography (PET/CT), but occult on monoenergetic computed tomography (CT) by virtue of being either isodense or nearly isodense to surrounding normal bone.

Materials and Methods

We present 4 cases in which DECT was used to detect various malignant bone lesions and was successfully used to direct percutaneous DECT-guided bone biopsies.

Results

Two of the lesions were solid tumor metastases (breast and prostate carcinoma), whereas two others were hematological malignancies (leukemia and lymphoma). This technique enabled us to confidently and accurately direct the biopsy needle into the target lesion.

Conclusion

The authors demonstrate that the DECT VNCa bone marrow algorithm may be helpful in identifying isodense bone lesions of various histologies and may be used to guide percutaneous bone biopsies. This technique may help to maximize diagnostic yield, minimize the number of passes into the region of concern, and prevent patients from undergoing repeat biopsy.

Glazebrook KN, Guimarães LS, Murthy NS, et al. Identification of intraarticular and periarticular uric acid crystals with dual-energy CT: initial evaluation. Radiology. 2011;261(2):516–24.CrossRefPubMed

Nicolaou S, Liang T, Murphy DT, Korzan JR, Ouellette H, Munk P. Dual-energy CT: a promising new technique for assessment of the musculoskeletal system. AJR Am J Roentgenol. 2012;199(5 Suppl):S78–86.CrossRefPubMed

Deng K, Zhang CQ, Li W, et al. Preliminary application of high-definition CT gemstone spectral imaging in hand and foot tendons. Korean J Radiol. 2012;13(6):743–51.CrossRefPubMedPubMedCentral

Glazebrook KN, Brewerton LJ, Leng S, et al. Case-control study to estimate the performance of dual-energy computed tomography for anterior cruciate ligament tears in patients with history of knee trauma. Skeletal Radiol. 2014;43(3):297–305.CrossRefPubMed

Coupal TM, Mallinson PI, McLaughlin P, Nicolaou S, Munk PL, Ouellette H. Peering through the glare: using dual-energy CT to overcome the problem of metal artefacts in bone radiology. Skeletal Radiol. 2014;43(5):567–75.CrossRefPubMed

Reddy T, McLaughlin PD, Mallinson PI, et al. Detection of occult, undisplaced hip fractures with a dual-energy CT algorithm targeted to detection of bone marrow edema. Emerg Radiol. 2015;22(1):25–9.CrossRefPubMed

Gondim Teixeira PA, Gervaise A, Louis M, et al. Musculoskeletal wide detector CT: principles, techniques and applications in clinical practice and research. Eur J Radiol. 2015;84(5):892–900.CrossRefPubMed

Sun X, Shao X, Chen H. The value of energy spectral CT in the differential diagnosis between benign and malignant soft tissue masses of the musculoskeletal system. Eur J Radiol. 2015;84(6):1105–8.CrossRefPubMed

Mallinson PI, Coupal TM, McLaughlin PD, Nicolaou S, Munk PL, Ouellette HA. Dual-energy CT for the musculoskeletal system. Radiology. 2016;281(3):690–707.CrossRefPubMed

10.

Burke CJ, Didolkar MM, Barnhart HX, Vinson EN. The use of routine non density calibrated clinical computed tomography data as a potentially useful screening tool for identifying patients with osteoporosis. Clin Cases Miner Bone Metab. 2016;13(2):135–40.PubMedPubMedCentral

11.

Diekhoff T, Hermann KG, Pumberger M, Hamm B, Putzier M, Fuchs M. Dual-energy CT virtual non-calcium technique for detection of bone marrow edema in patients with vertebral fractures: a prospective feasibility study on a single-source volume CT scanner. Eur J Radiol. 2017;87:59–65.CrossRefPubMed

12.

Hackenbroch C, Riesner HJ, Lang P, et al. Dual energy computed tomography in musculoskeletal imaging, with focus on fragility fractures of the pelvis. Z Orthop Unfall. 2017;155(6):708–15.CrossRefPubMed

13.

Khanduri S, Goyal A, Singh B, et al. The utility of dual energy computed tomography in musculoskeletal imaging. J Clin Imaging Sci. 2017;7:34.CrossRefPubMedPubMedCentral

14.

Thomas C, Schabel C, Krauss B, et al. Dual-energy CT: virtual calcium subtraction for assessment of bone marrow involvement of the spine in multiple myeloma. AJR Am J Roentgenol. 2015;204(3):W324–31.CrossRefPubMed

15.

Chang IJ, Ilaslan H, Sundaram M, Schils J, Subhas N. CT-guided percutaneous biopsy of sclerotic bone lesions: diagnostic outcomes. Skeletal Radiol. 2018;47(5):661–9.CrossRefPubMed

16.

Espinosa LA, Jamadar DA, Jacobson JA, et al. CT-guided biopsy of bone: a radiologist's perspective. AJR Am J Roentgenol. 2008;190(5):W283–9.CrossRefPubMed

17.

Rehm J, Veith S, Akbar M, Kauczor HU, Weber MA. CT-guided percutaneous spine biopsy in suspected infection or malignancy: a study of 214 patients. Rofo. 2016;188(12):1156–62.CrossRefPubMed

18.

Song Y, Kwon JW. Percutaneous CT-guided sternal biopsy: factors affecting the diagnostic yield. Acta Radiol. 2017;58(7):825–33.CrossRefPubMed

19.

Cox M, Pukenas B, Poplawski M, Bress A, Deely D, Flanders A. CT-guided cervical bone biopsy in 43 patients: diagnostic yield and safety at two large tertiary care hospitals. Acad Radiol. 2016;23(11):1372–5.CrossRefPubMed

20.

Garg V, Kosmas C, Josan ES, et al. Computed tomography-guided percutaneous biopsy for vertebral neoplasms: a department's experience and hybrid biopsy technique to improve yield. Neurosurg Focus. 2016;41(2):E17.CrossRefPubMed

21.

Chang CY, Huang AJ, Bredella MA, et al. Percutaneous CT-guided needle biopsies of musculoskeletal tumors: a 5-year analysis of non-diagnostic biopsies. Skeletal Radiol. 2015;44(12):1795–803.CrossRefPubMed

22.

Maciel MJ, Tyng CJ, Barbosa PN, et al. Computed tomography-guided percutaneous biopsy of bone lesions: rate of diagnostic success and complications. Radiol Bras. 2014;47(5):269–74.CrossRefPubMedPubMedCentral

23.

Li Y, Du Y, Luo TY, et al. Factors influencing diagnostic yield of CT-guided percutaneous core needle biopsy for bone lesions. Clin Radiol. 2014;69(1):e43–7.CrossRefPubMed

24.

Kaltsikis I, Chourmouzi D, Drevelegas K, Potsi S, Moumtzouoglou A, Drevelegas A. Core needle biopsy of spinal lesions under CT guidance: review of 79 cases. J Neurol Surg A Cent Eur Neurosurg. 2012;73(4):199–203.CrossRefPubMed

25.

Hwang S, Lefkowitz RA, Landa J, et al. Percutaneous CT-guided bone biopsy: diagnosis of malignancy in lesions with initially indeterminate biopsy results and CT features associated with diagnostic or indeterminate results. AJR Am J Roentgenol. 2011;197(6):1417–25.CrossRefPubMed

26.

Omura MC, Motamedi K, UyBico S, Nelson SD, Seeger LL. Revisiting CT-guided percutaneous core needle biopsy of musculoskeletal lesions: contributors to biopsy success. AJR Am J Roentgenol. 2011;197(2):457–61.CrossRefPubMed

27.

Rimondi E, Rossi G, Bartalena T, et al. Percutaneous CT-guided biopsy of the musculoskeletal system: results of 2027 cases. Eur J Radiol. 2011;77(1):34–42.CrossRefPubMed

28.

Rimondi E, Staals EL, Errani C, et al. Percutaneous CT-guided biopsy of the spine: results of 430 biopsies. Eur Spine J. 2008;17(7):975–81.CrossRefPubMedPubMedCentral

29.

Hillen TJ, Talbert RJ, Friedman MV, et al. Biopsy of CT-occult bone lesions using anatomic landmarks for CT guidance. AJR Am J Roentgenol. 2017;209(1):214–21.CrossRefPubMed

30.

Sequeiros RB, Fritz J, Ojala R, Carrino JA. Percutaneous magnetic resonance imaging-guided bone tumor management and magnetic resonance imaging-guided bone therapy. Top Magn Reson Imaging. 2011;22(4):171–7.CrossRefPubMed

31.

Carrino JA, Khurana B, Ready JE, Silverman SG, Winalski CS. Magnetic resonance imaging-guided percutaneous biopsy of musculoskeletal lesions. J Bone Joint Surg Am. 2007;89(10):2179–87.PubMed

32.

Guo W, Hao B, Chen HJ, et al. PET/CT-guided percutaneous biopsy of FDG-avid metastatic bone lesions in patients with advanced lung cancer: a safe and effective technique. Eur J Nucl Med Mol Imaging. 2017;44(1):25–32.CrossRefPubMed

33.

Cornelis F, Silk M, Schoder H, et al. Performance of intra-procedural 18-fluorodeoxyglucose PET/CT-guided biopsies for lesions suspected of malignancy but poorly visualized with other modalities. Eur J Nucl Med Mol Imaging. 2014;41(12):2265–72.CrossRefPubMedPubMedCentral

34.

Palmer WE, Simeone FJ. Can dual-energy CT challenge MR imaging in the diagnosis of focal infiltrative bone marrow lesions? Radiology. 2018;286(1):214–6.CrossRefPubMed

35.

Kosmala A, Weng AM, Krauss B, Knop S, Bley TA, Petritsch B. Dual-energy CT of the bone marrow in multiple myeloma: diagnostic accuracy for quantitative differentiation of infiltration patterns. Eur Radiol. 2018. https://doi.org/10.1007/s00330-018-5537-5.CrossRefPubMed

36.

Kosmala A, Weng AM, Heidemeier A, et al. Multiple myeloma and dual-energy CT: diagnostic accuracy of virtual noncalcium technique for detection of bone marrow infiltration of the spine and pelvis. Radiology. 2018;286(1):205–13.CrossRefPubMed

37.

Yuan Y, Zhang Y, Lang N, Li J, Yuan H. Differentiating malignant vertebral tumours from non-malignancies with CT spectral imaging: a preliminary study. Eur Radiol. 2015;25(10):2945–50.CrossRefPubMed

38.

Dong Y, Zheng S, Machida H, et al. Differential diagnosis of osteoblastic metastases from bone islands in patients with lung cancer by single-source dual-energy CT: advantages of spectral CT imaging. Eur J Radiol. 2015;84(5):901–7.CrossRefPubMed

39.

Chen H, Jia M, Xu W. Malignant bone tumor intramedullary invasion: evaluation with dual-energy computed tomography in a rabbit model. J Comput Assist Tomogr. 2015;39(1):70–4.CrossRefPubMed

40.

Zheng S, Dong Y, Miao Y, et al. Differentiation of osteolytic metastases and Schmorl's nodes in cancer patients using dual-energy CT: advantage of spectral CT imaging. Eur J Radiol. 2014;83(7):1216–21.CrossRefPubMed

41.

Lee YH, Kim S, Lim D, Suh JS, Song HT. Spectral parametric segmentation of contrast-enhanced dual-energy CT to detect bone metastasis: feasibility sensitivity study using whole-body bone scintigraphy. Acta Radiol. 2015;56(4):458–64.CrossRefPubMed

42.

Crone-Münzebrock W, Carl UM. Dual-energy CT-scan quantification of recalcification in osteolyses of the vertebral body due to mammary carcinomas in the course of antineoplastic treatment. Clin Exp Metastasis. 1990;8(2):173–9.CrossRefPubMed

43.

McCollough CH, Leng S, Yu L, Fletcher JG. Dual- and multi-energy CT: principles, technical approaches, and clinical applications. Radiology. 2015;276(3):637–53.CrossRefPubMedPubMedCentral

44.

Omoumi P, Becce F, Racine D, Ott JG, Andreisek G, Verdun FR. Dual-energy CT: basic principles, technical approaches, and applications in musculoskeletal imaging I. Semin Musculoskelet Radiol. 2015;19(5):431–7.CrossRefPubMed

45.

Omoumi P, Verdun FR, Guggenberger R, Andreisek G, Becce F. Dual-energy CT: basic principles, technical approaches, and applications in musculoskeletal imaging II. Semin Musculoskelet Radiol. 2015;19(5):438–45.CrossRefPubMed

46.

Wu JS, Goldsmith JD, Horwich PJ, Shetty SK, Hochman MG. Bone and soft-tissue lesions: what factors affect diagnostic yield of image-guided core-needle biopsy? Radiology. 2008;248(3):962–70.CrossRefPubMed

47.

Virayavanich W, Ringler MD, Chin CT, et al. CT-guided biopsy of bone and soft-tissue lesions: role of on-site immediate cytologic evaluation. J Vasc Interv Radiol. 2011;22(7):1024–30.CrossRefPubMed

Titel: Initial experience with dual-energy computed tomography-guided bone biopsies of bone lesions that are occult on monoenergetic CT
verfasst von: Michael C. Burke
Ankur Garg
Jonathan M. Youngner
Swati D. Deshmukh
Imran M. Omar
Publikationsdatum: 20.10.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Skeletal Radiology / Ausgabe 4/2019
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-018-3087-1

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Initial experience with dual-energy computed tomography-guided bone biopsies of bone lesions that are occult on monoenergetic CT

Abstract

Objective

Materials and Methods

Results

Conclusion

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