Ausgabe 3/2022
Inhalt (24 Artikel)
AM22, a novel synthetic microRNA, inhibits the proliferation of colorectal cancer cells by targeting core binding factor subunit β (CBFB)
Fanyi Meng, Jiawei Li, Yajing Qiu, Haiyang Zhang, Hongjian Zhang, Weipeng Wang
Radiosensitizing effect of galunisertib, a TGF-ß receptor I inhibitor, on head and neck squamous cell carcinoma in vitro
Bernhard J. Jank, Teresa Lenz, Markus Haas, Lorenz Kadletz-Wanke, Nicholas J. Campion, Julia Schnoell, Gregor Heiduschka, Karin Macfelda
IMB5036, a novel pyridazinone compound, inhibits hepatocellular carcinoma growth and metastasis
Xing Lv, Qi Zhao, Yanqun Dong, Lijun Yang, Jianhua Gong, Yanbo Zheng, Tao Yang
Biological evaluation of complexes of cyclopentadienyl M(CO)3+ (M = Re, 99mTc) with high blood–brain barrier penetration potential as brain cancer agents
B. Mavroidi, A. Kaminari, K. Makrypidi, A. Shegani, P. Bouziotis, I. Pirmettis, M. Papadopoulos, M. Sagnou, M. Pelecanou
Blockade of Myd88 signaling by a novel MyD88 inhibitor prevents colitis-associated colorectal cancer development by impairing myeloid-derived suppressor cells
Lu Wang, Dan Hu, Bin Xie, Lin Xie
Investigation of the effects of the toll-like receptor 4 pathway on immune checkpoint vista in pancreatic cancer
Kubra Sena Bas Topcu, Emine Nedime Korucu, Esma Menevse, Nadir Kocak, Tugce Duran
The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma
Chang-Won Kang, Katherine M. Hannan, Anneke C. Blackburn, Amos H. P. Loh, Kuick Chik Hong, Goh Jian Yuan, Nadine Hein, Denis Drygin, Ross D. Hannan, Lucy A. Coupland
IL-10 contributes to gemcitabine resistance in extranodal NK/T-cell lymphoma cells via ABCC4
Jia Huo, Lijun Fu, Mengyuan Jin, Zhaoming Li, Mingzhi Zhang
Actively targeted delivery of SN38 by ultrafine iron oxide nanoparticle for treating pancreatic cancer
Ting Xue, Peijia Xu, Jonathan Padelford, Xingkui Xue, Alyssa Y. Wu, Yuancheng Li, Liya Wang
The kinesin Eg5 inhibitor K858 exerts antiproliferative and proapoptotic effects and attenuates the invasive potential of head and neck squamous carcinoma cells
Alice Nicolai, Samanta Taurone, Simone Carradori, Marco Artico, Antonio Greco, Roberta Costi, Susanna Scarpa
Poly-guanidine shows high cytotoxicity in glioma cell cultures and glioma stem cells
Marcela Márquez, Karl Holmberg Olausson, Ayodele Alaiya, Sten Nilsson, Lennart Meurling, Anders R. Holmberg
Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model
Antônio Bruno Alves-Silva, Bruna Alves Fenerich, Natasha Peixoto Fonseca, Jaqueline Cristina Fernandes, Juan Luiz Coelho-Silva, Diego Antonio Pereira-Martins, Thiago Mantello Bianco, Priscila Santos Scheucher, Eduardo Magalhães Rego, Fernando Chahud, João Agostinho Machado-Neto, Lorena Lôbo Figueiredo-Pontes, Fabiola Traina
First-in-human trial exploring safety, antitumor activity, and pharmacokinetics of Sym013, a recombinant pan-HER antibody mixture, in advanced epithelial malignancies
Jordan Berlin, Anthony W. Tolcher, Cliff Ding, Jennifer G. Whisenant, Ivan D. Horak, Debra L. Wood, Paul I. Nadler, Ulla Holm Hansen, Johan Lantto, Niels Jørgen Ø. Skartved, Mikkel W. Pedersen, Amita Patnaik
Phase I trial of ATM inhibitor M3541 in combination with palliative radiotherapy in patients with solid tumors
Saiama N. Waqar, Clifford Robinson, Anthony J. Olszanski, Alexander Spira, Melissa Hackmaster, Luisa Lucas, Laura Sponton, Hulin Jin, Ursula Hering, Damien Cronier, Marianna Grinberg, Annick Seithel-Keuth, Ivan Diaz-Padilla, Jordan Berlin
A pharmacokinetic study to comparatively evaluate the bioequivalence and safety of a humanized recombinant monoclonal antibody targeting human epidermal growth factor receptor-2 with the reference Herceptin in healthy Chinese subjects
Fangfang Ding, Jie Huang, Zeying Feng, Yun Kuang, Shuang Yang, Yuxia Xiang, Chan Zou, Guoping Yang
An exploration of trifluridine/tipiracil in combination with irinotecan in patients with pretreated advanced gastric cancer
Takuro Mizukami, Keiko Minashi, Hiroki Hara, Tomohiro Nishina, Yusuke Amanuma, Naoki Takahashi, Akio Nakasya, Masaki Takahashi, Takako Eguchi Nakajima
Phase II study of dichloroacetate, an inhibitor of pyruvate dehydrogenase, in combination with chemoradiotherapy for unresected, locally advanced head and neck squamous cell carcinoma
Steven F. Powell, Miroslaw Mazurczak, Elie G. Dib, Jonathon S. Bleeker, Louis H. Geeraerts, Matthew Tinguely, Michele M. Lohr, Steven C. McGraw, Ashley W. Jensen, Christie A. Ellison, Lora J. Black, Susan E. Puumala, Valerie J. Reed, W. Keith Miskimins, John H. Lee, William C. Spanos
Efficacy and safety of ramucirumab and docetaxel in previously treated patients with squamous cell lung cancer: a multicenter retrospective cohort study
Hayato Kawachi, Motohiro Tamiya, Kinnosuke Matsumoto, Akihiro Tamiya, Takafumi Yanase, Satoshi Tanizaki, Toru Kumagai
Real-world data of off-label drug use in patients with actionable genomic alterations on next-generation sequencing
Gabriel Roman Souza, Ahmed Abdalla, Sukeshi Arora, Daruka Mahadevan
Orelabrutinib-bruton tyrosine kinase inhibitor-based regimens in the treatment of central nervous system lymphoma: a retrospective study
Jing-Jing Wu, Wen-Hua Wang, Meng Dong, Shan-Shan Ma, Xu-Dong Zhang, Li-Nan Zhu, Song-Tao Niu, Meng-Jie Ding, Jie-Ming Zhang, Lei Zhang, Xin Li, Ling Li, Zhen-Chang Sun, Xin-Hua Wang, Xiao-Rui Fu, Zhao-Ming Li, Yu Chang, Fei-Fei Nan, Jia-Qin Yan, Hui Yu, Xiao-Long Wu, Zhi-Yuan Zhou, Ming-Zhi Zhang
The 45-month therapy outcomes of permanent seed implantation and radical prostatectomy for prostate cancer patients
Chao Li, Mengdong Zhang, Jianwen Wang, Xiaodong Zhang
The addition of the immunomodulator mifamurtide to adjuvant chemotherapy for early osteosarcoma: a retrospective analysis
Stefania Kokkali, Ioannis Kotsantis, Elpida Magou, Talagani Sophia, Theodoros Kormas, Giakoumis Diakoumis, Nikolaos Spathas, Amanda Psyrri, Alexandros Ardavanis
Author Correction: Increased DKC1 expression in glioma and its significance in tumor cell proliferation, migration and invasion
Fa-an Miao, Kun Chu, Hai-rong Chen, Meng Zhang, Pei-cong Shi, Jin Bai, Yong-ping You
Author Correction: Phase I trial of ATM inhibitor M3541 in combination with palliative radiotherapy in patients with solid tumors
Saiama N. Waqar, Clifford Robinson, Anthony J. Olszanski, Alexander Spira, Melissa Hackmaster, Luisa Lucas, Laura Sponton, Hulin Jin, Ursula Hering, Damien Cronier, Marianna Grinberg, Annick Seithel-Keuth, Ivan Diaz-Padilla, Jordan Berlin