Erschienen in:
06.05.2021 | Invited Commentary
Invited Commentary: “Familial Non-Medullary Thyroid Carcinoma in Pediatric Age: Our Surgical Experience.”
verfasst von:
Sarah Jane Commander, Tamara N. Fitzgerald
Erschienen in:
World Journal of Surgery
|
Ausgabe 8/2021
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Excerpt
Thyroid cancer remains uncommon in children, but the incidence has risen over the last 4 decades. Non-medullary thyroid cancer accounts for most of the disease burden in pediatric patients and is distinct from adult-onset disease in clinical presentation, pathophysiology and long-term outcomes. In their manuscript entitled “Familial Non-Medullary Thyroid Carcinoma in pediatric age: our surgical experience”, Spinelli and colleagues report on their experience with familial (FNMTC) and sporadic (SNMTC) non-medullary thyroid carcinoma [
1]. The paper is a retrospective review of 76 pediatric patients, 20 with FNMTC and 56 with SNMTC forms of non-medullary thyroid carcinoma. In this report, patients with FNMTC had a higher proportion of metastasis at diagnosis, persistence of disease after one year of treatment, and number of radioactive iodine treatment sessions than patients with SNMTC. The authors conclude that pediatric patients with FNMTC variant may be a more aggressive form of malignancy and encourage physicians to pay particular attention to family history when treating any pediatric patient with non-medullary thyroid carcinoma. …
