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01.12.2014 | Case report | Ausgabe 1/2014 Open Access

Italian Journal of Pediatrics 1/2014

Kawasaki disease in a girl with turner syndrome: a remarkable association

Zeitschrift:
Italian Journal of Pediatrics > Ausgabe 1/2014
Autoren:
Stefano Stagi, Stefania Losi, Francesco Chiarelli, Maurizio de Martino, Fernanda Falcini
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1824-7288-40-24) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that there are no conflicts of interest that could be perceived as prejudicing the impartiality of the research reported.

Authors’ contributions

SS performed the endocrinological evaluation and wrote the paper. SL performed the gynaecological evaluation and participated in writing the paper. FC performed the endocrinological evaluation and participated in writing the paper. FF performed the rheumatologic evaluation. MdM participated in the rheumatologic evaluation and in writing the paper. All authors read and approved the final manuscript.

Abstract

We describe a girl with Turner syndrome, a genetic disorder of the X chromosome in a phenotypic female at increased risk of autoimmune and immunological diseases, who developed Kawasaki disease at the age of four years.
Given the possible relationship between these two disorders, we recommend suspecting Kawasaki disease in patients with Turner syndrome who present with persistent fever of unknown origin and who are not responsive to antibiotic therapy. Attention should be given to this phenomenon, as patients with Turner syndrome are themselves at higher risk of cardiovascular defects. Further studies are needed to better clarify this issue.
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