Skip to main content
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 10/2005

01.10.2005 | Original Paper

Childhood adversities as risk factors for adult mental disorders

Results from the Health 2000 study

verfasst von: Sami Pirkola, Erkki Isometsä, Hillevi Aro, Laura Kestilä, Juha Hämäläinen, Juha Veijola, Olli Kiviruusu, Jouko Lönnqvist

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 10/2005

Einloggen, um Zugang zu erhalten

Abstract

Background

The sex-specific role of stressful or traumatic childhood experiences and adverse circumstances in developing adulthood mental disorders is complex and still in need of comprehensive research.

Methods

Within the Health 2000 project in Finland, a representative sample of 4,076 subjects aged 30–64 years were investigated to examine associations between a set of retrospectively self-reported adverse environmental factors during childhood (0–16 years) and mental disorders diagnosed in the past 12 months by the Munich Composite International Diagnostic Interview.

Results

Of the 60% of adults reporting at least one childhood adversity, 17% had a current (past 12 months) mental disorder, compared to 10% of the non-reporters. A moderate dose–response relationship between the total number of adversities and current disorders was observed. Paternal mental health problems associated particularly strongly with male depressive disorders (OR 4.46), and maternal mental health problems with female depressive disorders (OR 3.20). Although seldom reported, maternal alcohol problems associated with alcohol use disorders in both sexes. Being bullied at school and childhood family discord predicted a variety of adulthood disorders in both sexes. All these four adversity items were more typical for depressive disorders with an earlier onset. Among females, more adversities were associated with mental disorders and their statistical significance was greater than among males.

Conclusions

There are marked sex differences and several diagnosis-related patterns in the associations between reported childhood experiences and environmental circumstances and adulthood mental disorders. The impact of adversities is probably composed of a wide range of factors from direct causal associations to complex, interacting environmental effects. Variations in the reported associations reflect the differing genetic and environmental transmission mechanisms of mental disorders.
Literatur
1.
Zurück zum Zitat Pirkola S, Isometsä E, Suvisaari J et al (2005) DSM-IV mood-, anxiety- and alcohol use disorders and their comorbidity in the Finnish general population. Results from the Health 2000 study. Soc Psychiatry Psychiatr Epidemiol 40:1–10PubMed Pirkola S, Isometsä E, Suvisaari J et al (2005) DSM-IV mood-, anxiety- and alcohol use disorders and their comorbidity in the Finnish general population. Results from the Health 2000 study. Soc Psychiatry Psychiatr Epidemiol 40:1–10PubMed
2.
Zurück zum Zitat de Graaf R, Bijl RV, Smit F, Vollebergh WA, Spijker J (2002) Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study. Am J Psychiatry 159:620–629PubMed de Graaf R, Bijl RV, Smit F, Vollebergh WA, Spijker J (2002) Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study. Am J Psychiatry 159:620–629PubMed
3.
Zurück zum Zitat Kessler RC, Nelson CB, McGonagle KA, Liu J, Swartz M, Blazer DG (1996) Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey. Br J Psychiatry Suppl 17–30 Kessler RC, Nelson CB, McGonagle KA, Liu J, Swartz M, Blazer DG (1996) Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey. Br J Psychiatry Suppl 17–30
4.
Zurück zum Zitat Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lepine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martinez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacin C, Romera B, Taub N, Vollebergh WAM (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109:21–27CrossRef Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lepine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martinez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacin C, Romera B, Taub N, Vollebergh WAM (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109:21–27CrossRef
5.
Zurück zum Zitat Mäkikyro T, Sauvola A, Moring J et al (1998) Hospital-treated psychiatric disorders in adults with a single-parent and two-parent family background: a 28-year follow-up of the 1966 Northern Finland Birth Cohort. Fam Process 37:335–344PubMed Mäkikyro T, Sauvola A, Moring J et al (1998) Hospital-treated psychiatric disorders in adults with a single-parent and two-parent family background: a 28-year follow-up of the 1966 Northern Finland Birth Cohort. Fam Process 37:335–344PubMed
6.
Zurück zum Zitat Sauvola A, Räsänen PK, Joukamaa MI, Jokelainen J, Jarvelin MR, Isohanni MK (2001) Mortality of young adults in relation to single-parent family background. A prospective study of the northern Finland 1966 birth cohort. Eur J Public Health 11:284–286CrossRefPubMed Sauvola A, Räsänen PK, Joukamaa MI, Jokelainen J, Jarvelin MR, Isohanni MK (2001) Mortality of young adults in relation to single-parent family background. A prospective study of the northern Finland 1966 birth cohort. Eur J Public Health 11:284–286CrossRefPubMed
7.
Zurück zum Zitat Warner V, Mufson L, Weissman MM (1995) Offspring at high and low risk for depression and anxiety: mechanisms of psychiatric disorder. J Am Acad Child Adolesc Psychiatry 34:786–797PubMed Warner V, Mufson L, Weissman MM (1995) Offspring at high and low risk for depression and anxiety: mechanisms of psychiatric disorder. J Am Acad Child Adolesc Psychiatry 34:786–797PubMed
8.
Zurück zum Zitat Dierker LC, Merikangas KR, Szatmari P (1999) Influence of parental concordance for psychiatric disorders on psychopathology in offspring. J Am Acad Child Adolesc Psychiatry 38:280–288PubMed Dierker LC, Merikangas KR, Szatmari P (1999) Influence of parental concordance for psychiatric disorders on psychopathology in offspring. J Am Acad Child Adolesc Psychiatry 38:280–288PubMed
9.
Zurück zum Zitat Marmorstein NR, Malone SM, Iacono WG (2004) Psychiatric disorders among offspring of depressed mothers: associations with paternal psychopathology. Am J Psychiatry 161:1588–1594CrossRefPubMed Marmorstein NR, Malone SM, Iacono WG (2004) Psychiatric disorders among offspring of depressed mothers: associations with paternal psychopathology. Am J Psychiatry 161:1588–1594CrossRefPubMed
10.
Zurück zum Zitat Kessler RC, Davis CG, Kendler KS (1997) Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey. Psychol Med 27:1101–1119PubMed Kessler RC, Davis CG, Kendler KS (1997) Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey. Psychol Med 27:1101–1119PubMed
11.
Zurück zum Zitat Veijola J, Puukka P, Lehtinen V, Moring J, Lindholm T, Väisänen E (1998) Sex differences in the association between childhood experiences and adult depression. Psychol Med 28:21–27CrossRefPubMed Veijola J, Puukka P, Lehtinen V, Moring J, Lindholm T, Väisänen E (1998) Sex differences in the association between childhood experiences and adult depression. Psychol Med 28:21–27CrossRefPubMed
12.
Zurück zum Zitat McLeod JD (1991) Childhood parental loss and adult depression. J Health Soc Behav 32:205–220PubMed McLeod JD (1991) Childhood parental loss and adult depression. J Health Soc Behav 32:205–220PubMed
13.
Zurück zum Zitat Rodgers B (1994) Pathways between parental divorce and adult depression. J Child Psychol Psychiatry 35:1289–1308PubMed Rodgers B (1994) Pathways between parental divorce and adult depression. J Child Psychol Psychiatry 35:1289–1308PubMed
14.
15.
Zurück zum Zitat Reiss D, Cederblad M, Pedersen NL et al (2001a) Genetic probes of three theories of maternal adjustment. II. Genetic and environmental influences. Fam Process 40:261–272PubMed Reiss D, Cederblad M, Pedersen NL et al (2001a) Genetic probes of three theories of maternal adjustment. II. Genetic and environmental influences. Fam Process 40:261–272PubMed
16.
Zurück zum Zitat Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF (2004) Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 82:217–225CrossRefPubMed Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF (2004) Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 82:217–225CrossRefPubMed
17.
Zurück zum Zitat Anda RF, Whitfield CL, Felitti VJ et al (2002) Adverse childhood experiences, alcoholic parents, and later risk of alcoholism and depression. Psychiatr Serv 53:1001–1009CrossRefPubMed Anda RF, Whitfield CL, Felitti VJ et al (2002) Adverse childhood experiences, alcoholic parents, and later risk of alcoholism and depression. Psychiatr Serv 53:1001–1009CrossRefPubMed
18.
Zurück zum Zitat Caspi A, McClay J, Moffitt TE et al (2002) Role of genotype in the cycle of violence in maltreated children. Science 297:851–854CrossRefPubMed Caspi A, McClay J, Moffitt TE et al (2002) Role of genotype in the cycle of violence in maltreated children. Science 297:851–854CrossRefPubMed
19.
Zurück zum Zitat Kendler KS, Prescott CA, Myers J, Neale MC (2003) The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 60:929–937PubMed Kendler KS, Prescott CA, Myers J, Neale MC (2003) The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 60:929–937PubMed
20.
Zurück zum Zitat Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA (2003) Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety. Arch Gen Psychiatry 60:789–796PubMed Kendler KS, Hettema JM, Butera F, Gardner CO, Prescott CA (2003) Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety. Arch Gen Psychiatry 60:789–796PubMed
21.
Zurück zum Zitat Foley DL, Eaves LJ, Wormley B et al (2004) Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Arch Gen Psychiatry 61:738–744PubMed Foley DL, Eaves LJ, Wormley B et al (2004) Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Arch Gen Psychiatry 61:738–744PubMed
22.
Zurück zum Zitat Marmorstein NR, Iacono WG (2004) Major depression and conduct disorder in youth: associations with parental psychopathology and parent–child conflict. J Child Psychol Psychiatry 45:377–386CrossRefPubMed Marmorstein NR, Iacono WG (2004) Major depression and conduct disorder in youth: associations with parental psychopathology and parent–child conflict. J Child Psychol Psychiatry 45:377–386CrossRefPubMed
23.
Zurück zum Zitat Reiss D, Pedersen NL, Cederblad M et al (2001b) Genetic probes of three theories of maternal adjustment. I. Recent evidence and a model. Fam Process 40:247–259PubMed Reiss D, Pedersen NL, Cederblad M et al (2001b) Genetic probes of three theories of maternal adjustment. I. Recent evidence and a model. Fam Process 40:247–259PubMed
24.
Zurück zum Zitat Aromaa A, Koskinen SE (2004) Health and functional capacity in Finland. Baseline results of the Health 2000 Health Examination Survey, vol. B12/2004. 2004 Publications of the National Public Health Institute. Hakapaino Oy, Helsinki Aromaa A, Koskinen SE (2004) Health and functional capacity in Finland. Baseline results of the Health 2000 Health Examination Survey, vol. B12/2004. 2004 Publications of the National Public Health Institute. Hakapaino Oy, Helsinki
25.
Zurück zum Zitat International Consortium in Psychiatric Epidemiology (2000) Cross-national comparisons of the prevalences and correlates of mental disorders. Bull WHO 78:413–426 International Consortium in Psychiatric Epidemiology (2000) Cross-national comparisons of the prevalences and correlates of mental disorders. Bull WHO 78:413–426
26.
Zurück zum Zitat Caspi A, Sugden K, Moffitt TE et al (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301:386–389CrossRefPubMed Caspi A, Sugden K, Moffitt TE et al (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301:386–389CrossRefPubMed
27.
Zurück zum Zitat Caspi A, Taylor A, Moffitt TE, Plomin R (2000) Neighborhood deprivation affects children's mental health: environmental risks identified in a genetic design. Psychol Sci 11:338–342CrossRefPubMed Caspi A, Taylor A, Moffitt TE, Plomin R (2000) Neighborhood deprivation affects children's mental health: environmental risks identified in a genetic design. Psychol Sci 11:338–342CrossRefPubMed
28.
Zurück zum Zitat Wainwright NW, Surtees PG (2002) Childhood adversity, gender and depression over the life-course. J Affect Disord 72:33–44CrossRefPubMed Wainwright NW, Surtees PG (2002) Childhood adversity, gender and depression over the life-course. J Affect Disord 72:33–44CrossRefPubMed
29.
Zurück zum Zitat Lieb R, Isensee B, Hofler M, Wittchen HU (2002) Parental depression and depression in offspring: evidence for familial characteristics and subtypes? J Psychiatr Res 36:237–246CrossRefPubMed Lieb R, Isensee B, Hofler M, Wittchen HU (2002) Parental depression and depression in offspring: evidence for familial characteristics and subtypes? J Psychiatr Res 36:237–246CrossRefPubMed
30.
Zurück zum Zitat Levitan RD, Rector NA, Sheldon T, Goering P (2003) Childhood adversities associated with major depression and/or anxiety disorders in a community sample of Ontario: issues of co-morbidity and specificity. Depress Anxiety 17:34–42CrossRefPubMed Levitan RD, Rector NA, Sheldon T, Goering P (2003) Childhood adversities associated with major depression and/or anxiety disorders in a community sample of Ontario: issues of co-morbidity and specificity. Depress Anxiety 17:34–42CrossRefPubMed
31.
Zurück zum Zitat Bijl RV, Cuijpers P, Smit F (2002) Psychiatric disorders in adult children of parents with a history of psychopathology. Soc Psychiatry Psychiatr Epidemiol 37:7–12PubMed Bijl RV, Cuijpers P, Smit F (2002) Psychiatric disorders in adult children of parents with a history of psychopathology. Soc Psychiatry Psychiatr Epidemiol 37:7–12PubMed
32.
Zurück zum Zitat Kaltiala-Heino R, Rimpelä M, Marttunen M, Rimpelä A, Rantanen P (1999) Bullying, depression, and suicidal ideation in Finnish adolescents: school survey. BMJ 319:348–351PubMed Kaltiala-Heino R, Rimpelä M, Marttunen M, Rimpelä A, Rantanen P (1999) Bullying, depression, and suicidal ideation in Finnish adolescents: school survey. BMJ 319:348–351PubMed
33.
Zurück zum Zitat Wolkind S, Coleman EZ (1983) Adult psychiatric disorder and childhood experiences. The validity of retrospective data. Br J Psychiatry 143:188–191PubMedCrossRef Wolkind S, Coleman EZ (1983) Adult psychiatric disorder and childhood experiences. The validity of retrospective data. Br J Psychiatry 143:188–191PubMedCrossRef
Metadaten
Titel
Childhood adversities as risk factors for adult mental disorders
Results from the Health 2000 study
verfasst von
Sami Pirkola
Erkki Isometsä
Hillevi Aro
Laura Kestilä
Juha Hämäläinen
Juha Veijola
Olli Kiviruusu
Jouko Lönnqvist
Publikationsdatum
01.10.2005
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 10/2005
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-005-0950-x

Weitere Artikel der Ausgabe 10/2005

Social Psychiatry and Psychiatric Epidemiology 10/2005 Zur Ausgabe

Hörschwäche erhöht Demenzrisiko unabhängig von Beta-Amyloid

29.05.2024 Hörstörungen Nachrichten

Hört jemand im Alter schlecht, nimmt das Hirn- und Hippocampusvolumen besonders schnell ab, was auch mit einem beschleunigten kognitiven Abbau einhergeht. Und diese Prozesse scheinen sich unabhängig von der Amyloidablagerung zu ereignen.

So wirken verschiedene Alkoholika auf den Blutdruck

23.05.2024 Störungen durch Alkohol Nachrichten

Je mehr Alkohol Menschen pro Woche trinken, desto mehr steigt ihr Blutdruck, legen Daten aus Dänemark nahe. Ob es dabei auch auf die Art des Alkohols ankommt, wurde ebenfalls untersucht.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

ADHS-Medikation erhöht das kardiovaskuläre Risiko

16.05.2024 Herzinsuffizienz Nachrichten

Erwachsene, die Medikamente gegen das Aufmerksamkeitsdefizit-Hyperaktivitätssyndrom einnehmen, laufen offenbar erhöhte Gefahr, an Herzschwäche zu erkranken oder einen Schlaganfall zu erleiden. Es scheint eine Dosis-Wirkungs-Beziehung zu bestehen.

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.