Introduction
Methods
Data sources
Inclusion and exclusion criteria
Study quality assessment
Measurements
Data extraction
Data synthesis and statistical analysis
Subgroup analyses
Sensitivity analyses
Results
Characteristics of included studies
Author | Date (in 2020) | Sample size | Response rate (%) | HCW subgroup (%) | Female (%) | Age (SD) | Prevalence of psychological impact** (%) | Quality score (AHRQ) | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Doctor | Nurse | Others | PTSS | Anxiety | Depression | Insomnia | |||||||
Region: Wuhan city | |||||||||||||
Du 2020 | 2.13–2.17 | 134 | 43.2 | 35.1 | 41.0 | 23.9 | 60.5 | 36.0 (8.1) | – | 20.1* | 12.7* | – | 5 |
Jiang 2020 | 1.27–2.1 | 175 | UNK | – | 100 | – | 100 | 31.7 (5.9) | – | – | – | – | 5 |
Li 2020a | 2.8–2.11 | 205 | UNK | – | 100 | – | 85.4 | UNK | 50.7 | – | – | – | 6 |
Li 2020b | Jan–Feb | 66 | 100 | – | 100 | – | 77.3 | UNK | – | – | – | – | 5 |
Li 2020c | UNK | 121 | 100 | – | 100 | – | 89.3 | 30.3 (5.4) | – | – | – | – | 5 |
Li 2020d | 2.8–2.15 | 4369 | 88.2 | 13.3 | 77.4 | 9.3 | 100 | UNK | 31.6 | 25.2 | 14.2 | – | 6 |
Li 2020e | 2.17–2.21 | 526 | UNK | – | 100 | – | 85.6 | 29.5 (5.0) | – | – | – | – | 3 |
Mo 2020 | 2.21 | 180 | 85.7 | UNK | UNK | UNK | 90.0 | 32.7 (6.5) | – | – | – | – | 5 |
Wang 2020 | UNK | 112 | UNK | UNK | UNK | UNK | 76.8 | 34.3 (6.1) | – | – | – | – | 2 |
Xu 2020a | UNK | 41 | UNK | – | 100 | – | 90.2 | 31.3 (2.5) | – | – | – | – | 4 |
Yuan 2020 | 2.7–2.20 | 309 | 85.6 | 43.7 | 48.5 | 7.8 | 76.4 | 34.0 (8.9) | – | – | – | – | 4 |
Zhu 2020b | 2.8–2.10 | 5062 | 77.1 | 19.8 | 67.5 | 12.7 | 85.0 | UNK | 29.8 | 24.1 | 13.4 | – | 8 |
Region: other cities in the Hubei province | |||||||||||||
Qi 2020 | Feb | 1306 | UNK | UNK | UNK | UNK | 80.4 | 33.1 (8.4) | – | – | – | 71.7* | 7 |
Xing 2020 | 1.22 | 40 | UNK | – | 100 | – | 95.0 | 31.4 (7.3) | – | – | – | – | 4 |
Xu 2020b | 2.9 | 42 | 100 | – | 100 | – | 100 | UNK | – | 35.7 | – | – | 5 |
Region: outside of the Hubei province | |||||||||||||
Cai 2020 | 2.1–2.7 | 1521 | UNK | 33.6 | 35.9 | 11.9 | 75.5 | UNK | – | – | – | – | 3 |
Cao 2020 | UNK | 37 | 100 | 43.2 | 56.8 | – | 78.4 | 32.8 (9.6) | – | – | 18.9 | – | 4 |
Chen 2020 | UNK | 206 | 93.7 | 84.0 | 16.0 | 69.5 | 34.0(8.9) | – | 0.5 | – | – | 3 | |
Deng 2020a | UNK | 60 | UNK | 30.0 | 70.0 | – | 86.7 | 32.2 (8.0) | – | – | – | – | 3 |
Deng 2020b | Jan | 68 | 100 | UNK | UNK | UNK | 66.2 | UNK | – | – | – | – | 3 |
Huang 2020a | 2.7–2.14 | 230 | 93.5 | 30.4 | 69.6 | – | 81.3 | 32.6 (6.2) | 27.4* | 7.0 | – | – | 6 |
Liang 2020 | 2.3–2.21 | 59 | UNK | 39.0 | 61.0 | – | UNK | UNK | – | – | – | – | 2 |
Liu 2020a | 2.1–2.18 | 1097 | 100 | – | 100 | – | 98.3 | 29.0 (5.9) | – | 3.5 | 9.7 | 2.8 | 3 |
Luo 2020 | 2.10–2.20 | 171 | 91.9 | UNK | UNK | UNK | 76.0 | UNK | – | 15.2 | 17.5 | – | 6 |
Pu 2020 | UNK | 867 | UNK | – | 100 | – | 95.6 | 30.8 (7.1) | 19.3 | – | – | – | 3 |
Sheng 2020 | UNK | 92 | 96.8 | – | 100 | – | 93.5 | 21.3 (1.0) | – | – | – | 17.4* | 4 |
Tian 2020 | 4.6–4.10 | 845 | 79.9 | 23.2 | 76.8 | – | 84.5 | 35.5 (6.7) | – | 20.7* | 45.6* | 27.0* | 4 |
Wu 2020a | UNK | 106 | 94.6 | – | 100 | – | 80.2 | 30.8 (4.5) | – | 29.3 | – | 64.2* | 4 |
Wu 2020b | UNK | 120 | UNK | UNK | UNK | UNK | 74.2 | 33.7 (12.2) | – | – | – | – | 3 |
Yin 2020 | 2.3–2.5 | 1266 | UNK | UNK | UNK | UNK | 74.7 | 35.2 (7.8) | – | 11.7 | 10.2 | – | 8 |
Zhu 2020a | 2.1–2.29 | 165 | 100 | 47.9 | 52.1 | – | 83.0 | 34.2 (8.1) | – | 20.0* | 44.2* | – | 6 |
Region: multiple centers nationwide or unknown | |||||||||||||
Guo 2020 | 2.18–2.20 | 11,118 | UNK | 30.3 | 53.1 | 16.6 | 74.8 | UNK | – | 5.0 | 13.5 | – | 3 |
Huang 2020b | 2.3–2.17 | 2250 | UNK | UNK | UNK | UNK | UNK | UNK | – | 35.6 | 19.8 | 23.6 | 4 |
Huangfu 2020 | UNK | 326 | 100 | – | 100 | – | 100 | 28.6 (12.2) | – | – | – | – | 3 |
Lai 2020 | 1.29–2.3 | 1257 | 68.7 | 39.2 | 60.8 | – | 76.7 | UNK | 35.0 | 12.3 | 14.8 | 7.8 | 6 |
Liu 2020b | 2.10–2.20 | 512 | 85.4 | UNK | UNK | UNK | 84.6 | UNK | – | 2.1 | – | – | 4 |
Liu 2020c | 2.17–2.24 | 4679 | UNK | 39.6 | 60.4 | – | 82.3 | 35.9 (9.0) | – | 5.2 | 19.8 | – | 4 |
Lv 2020 | UNK | 7071 | UNK | 52.2 | 47.8 | – | 71.2 | UNK | – | 35.6* | 37.0* | 35.2* | 3 |
Song 2020 | 2.28–3.18 | 14,825 | UNK | 41.1 | 58.9 | – | 64.3 | 34.0 (8.2) | 7.3 | – | 15.2 | – | 3 |
Sun 2020 | 1.31–2.4 | 442 | UNK | 12.0 | 78.7 | 9.3 | 83.3 | UNK | – | – | – | – | 5 |
Xiao 2020a | Jan–Feb | 180 | 81.8 | 45.6 | 54.4 | – | 71.7 | 32.3 (4.9) | – | 36.7 | – | 31.7 | 4 |
Xiao 2020b | 1.28 | 958 | UNK | 39.5 | 37.5 | 23.1 | 67.2 | UNK | – | 54.1* | 57.3* | – | 2 |
Zhang 2020a | 2.19–3.6 | 927 | UNK | UNK | UNK | UNK | 73.1 | UNK | – | 13.0 | 12.2 | 10.5 | 3 |
Zhang 2020b | 1.29–2.3 | 1563 | UNK | 29.0 | 63.0 | 8.0 | 82.7 | UNK | 37.4 | 12.9 | 17.2 | – | 5 |
Measurements | Prevalence criteriaa | Studies | ||
---|---|---|---|---|
PTSS | At least Moderate | At least mild | ||
Impact of Event Scale- Revised (IES-R) | ≥ 26 | ≥ 9 | Lai 2020; Li 2020b; Sun 2020a; Zhang 2020b; Zhu 2020b | |
PTSD Checklist Civilian Version (PCL-C) | > 38 | NA | Li 2020a; Wu 2020b | |
Post-Traumatic Stress Disorder Self-Rating Scale (PTSD-SS) | NA | 50 | Huang 2020b | |
PTSD Checklist for DSM-5 (PCL-5) | > 38 | > 33 | Song 2020 | |
Triage Assessment Form (TAF) | ≥ 13 | NA | Pu 2020 | |
Stanford Acute Stress Reaction Questionnaire (SASRQ) | Severity only | Xiao 2020a | ||
Vicarious Traumatization Questionnaire (VTQ) | Severity only | Li 2020e | ||
Anxiety | ||||
Zung Self-Rating Anxiety Scale (SAS) | ≥ 60 | ≥ 50 | Chen 2020a; Guo 2020; Huang 2020b; Liang 2020; Liu 2020a; Liu 2020d; Mo 2020; Pu 2020; Sheng 2020; Wu 2020a; Wu 2020b; Xiao 2020a; Xu 2020; Zhu 2020a | |
Generalized Anxiety Disorder 7-item (GAD-7) | ≥ 10 | ≥ 5 | Huang 2020a; Lai 2020; Li 2020b; Li 2020d; Liu 2020c; Luo 2020b; Lv 2020; Tian 2020; Zhang 2020a; Zhang 2020b; Zhu 2020b | |
Symptom Checklist 90; Anxiety subscale (SCL-90) | Severity only | Cai 2020b; Deng 2020b; Huangfu 2020; Jiang 2020; Wang 2020b; Xing 2020; Xu 2020 | ||
Hamilton Anxiety Rating Scale (HAM-A) | ≥ 21 | ≥ 14 | Li 2020c | |
Stress-related Questions associated with the H1N1 event; Anxiety subscale | Severity only | Deng 2020a | ||
Beck Anxiety Inventory (BAI) | NA | ≥ 8 | Du 2020 | |
Hospital Anxiety and Depression Scale; Anxiety subscale (HADS) | NA | ≥ 8 | Xiao 2020b | |
Depression | ||||
Patient Health Questionnaire 9-item (PHQ-9) | ≥ 10 | ≥ 5 | Cao 2020; Lai 2020; Li 2020b; Li 2020d; Liu 2020c; Luo 2020b; Lv 2020; Tian 2020; Zhang 2020a; Zhang 2020b; Zhu 2020b | |
Symptom Checklist 90; Depression subscale (SCL-90) | Severity only | Cai 2020b; Deng 2020b; Huangfu 2020; Jiang 2020; Wang 2020b; Xing 2020; Xu 2020 | ||
Zung Self-Rating Depression Scale (SDS) | ≥ 60 | ≥ 50 | Guo 2020; Liang 2020; Liu 2020d; Sheng 2020; Wu 2020a; Zhu 2020a | |
Center for Epidemiology Studies Depression Scale (CES-D) | > 28 | Huang 2020a; Song 2020 | ||
Beck Depression Inventory (BDI-II) | NA | ≥ 14 | Du 2020 | |
Hospital Anxiety and Depression Scale; Depression subscale (HADS) | NA | ≥ 8 | Xiao 2020b | |
Sleep disturbance | ||||
Pittsburgh Sleep Quality Index (PSQI) | ≥ 11 | ≥ 6 | Huang 2020a; Li 2020d; Qi 2020; Sheng 2020; Wu 2020a; Wu 2020b; Xiao 2020 | |
Insomnia Severity Index (ISI) | ≥ 15 | ≥ 8 | Lai 2020; Liu 2020c; Lv 2020; Tian 2020; Zhang 2020a; Zhang 2020b | |
Athens Insomnia Scale (AIS) | NA | > 6 | Qi 2020 | |
Profession-related burnoutb | ||||
Maslach Burn-out Inventory (MBI) | NA | Cao 2020; Wu 2020c | ||
Stress-related questions associated with the H1N1 event; Burnout subscale | Severity only | Deng 2020a |