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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 5/2019

15.04.2019 | KNEE

Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review

verfasst von: Silvan Hess, Lukas B. Moser, Felix Amsler, Henrik Behrend, Michael T. Hirschmann

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 5/2019

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Abstract

Purpose

There is a lack of knowledge about coronal alignment variability in osteoarthritic knees. Therefore, the purpose of this article was to systematically review the literature and collect data about the lower limb alignment including hip–knee–ankle angle (HKA), femoral mechanical angle (FMA), tibial mechanical angle (TMA) and the joint line convergence angle (JLCA) in osteoarthritic knees.

Methods

A systematic review was performed using the electronic databases MEDLINE (PubMed), EMBASE and Google Scholar. The following keywords were used: (morphology OR geometr* OR anatomy OR alignment OR phenotypes), (coronal OR neutral OR varus OR valgus), (knee OR lower limb OR femur OR tibia) and (osteoarthritis OR arthritis). Out of 110 full-text articles retrieved, 15 studies were included. Demographic information included author’s names, year of publication, imaging modality, sample size and patient demographics (i.e. sex, age, etc.). Descriptive statistics, such as means, ranges, and measures of variance [e.g. standard deviations, 95% confidence intervals (CI)] for all angles (HKA, FMA, TMA, JLCA) are presented.

Results

Thirteen studies reported mean overall HKA angles ranging from 163.5° ± 2.3° to 179.9° ± 4.8°. The mean HKA angles in females were between 164.1° ± 7.2° and 178.8° ± 4.8°, and in males between 163.4° ± 5.5° and 177.4° ± 3.9°. The lowest and highest reported HKA angles were − 27.7° and + 22.0°, respectively. Seven studies reported mean FMA angles. Mean values ranged from 92.7° ± 2.7° valgus to 88.6° ± 2° varus. The reported mean FMAs for male were 87.9° ± 0.5° to 90.7° ± 3° and for female 89.91° ± 2.8° to 92.9° ± 3.1°. Six studies reported mean TMA values. TMA ranged from 81.7° ± 3.9° varus to 87.7° ± 4.1° varus. Only three studies reported mean JLCA angles, which ranged from − 4.3° to − 6.4° ± 3.8°.

Conclusion

Osteoarthritic knees showed a huge variation in overall coronal limb alignment as well as in femoral and tibial coronal alignment. Current total knee arthroplasty (TKA) alignment philosophies and preoperative planning do not sufficiently consider these variation, which might be one reason for unhappy knees after TKA.

Level of evidence

IV, systematic review.
Literatur
1.
Zurück zum Zitat Bao Z, Qiao L, Qin J, Xu J, Zhou S et al (2017) The assessment of femoral shaft morphology in the sagittal plane in Chinese patients with osteoarthritis-a radiographic analysis. J Orthop Surg 12:127CrossRef Bao Z, Qiao L, Qin J, Xu J, Zhou S et al (2017) The assessment of femoral shaft morphology in the sagittal plane in Chinese patients with osteoarthritis-a radiographic analysis. J Orthop Surg 12:127CrossRef
2.
Zurück zum Zitat Bardakos N, Cil A, Thompson B, Stocks G (2007) Mechanical axis cannot be restored in total knee arthroplasty with a fixed valgus resection angle: a radiographic study. J Arthroplast 22:85–89CrossRef Bardakos N, Cil A, Thompson B, Stocks G (2007) Mechanical axis cannot be restored in total knee arthroplasty with a fixed valgus resection angle: a radiographic study. J Arthroplast 22:85–89CrossRef
3.
Zurück zum Zitat Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RMD et al (2007) Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheumatol 56:1204–1211CrossRef Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RMD et al (2007) Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheumatol 56:1204–1211CrossRef
4.
Zurück zum Zitat Choong PF, Dowsey MM, Stoney JD (2009) Does accurate anatomical alignment result in better function and quality of life? Comparing conventional and computer-assisted total knee arthroplasty. J Arthroplast 24:560–569CrossRef Choong PF, Dowsey MM, Stoney JD (2009) Does accurate anatomical alignment result in better function and quality of life? Comparing conventional and computer-assisted total knee arthroplasty. J Arthroplast 24:560–569CrossRef
5.
Zurück zum Zitat Cicuttini F, Wluka A, Hankin J, Wang Y (2004) Longitudinal study of the relationship between knee angle and tibiofemoral cartilage volume in subjects with knee osteoarthritis. Rheumatology 43:321–324CrossRefPubMed Cicuttini F, Wluka A, Hankin J, Wang Y (2004) Longitudinal study of the relationship between knee angle and tibiofemoral cartilage volume in subjects with knee osteoarthritis. Rheumatology 43:321–324CrossRefPubMed
6.
Zurück zum Zitat Cooke D, Scudamore A, Li J, Wyss U, Bryant T et al (1997) Axial lower-limb alignment: comparison of knee geometry in normal volunteers and osteoarthritis patients. Osteoarthr Cartil 5:39–47CrossRefPubMed Cooke D, Scudamore A, Li J, Wyss U, Bryant T et al (1997) Axial lower-limb alignment: comparison of knee geometry in normal volunteers and osteoarthritis patients. Osteoarthr Cartil 5:39–47CrossRefPubMed
7.
Zurück zum Zitat Cooke Harrison L, Khan B, Scudamore A, Chaudhary AM (2002) Analysis of limb alignment in the pathogenesis of osteoarthritis: a comparison of Saudi Arabian and Canadian cases. Rheumatol Int 22:160–164CrossRefPubMed Cooke Harrison L, Khan B, Scudamore A, Chaudhary AM (2002) Analysis of limb alignment in the pathogenesis of osteoarthritis: a comparison of Saudi Arabian and Canadian cases. Rheumatol Int 22:160–164CrossRefPubMed
8.
Zurück zum Zitat Deakin AH, Sarungi M (2014) A comparison of variable angle versus fixed angle distal femoral resection in primary total knee arthroplasty. J Arthroplast 29:1133–1137CrossRef Deakin AH, Sarungi M (2014) A comparison of variable angle versus fixed angle distal femoral resection in primary total knee arthroplasty. J Arthroplast 29:1133–1137CrossRef
9.
Zurück zum Zitat Felson DT, Cooke TDV, Niu J, Goggins J, Choi J et al (2009) Can anatomic alignment measured from a knee radiograph substitute for mechanical alignment from full limb films? Osteoarthr Cartil 17:1448–1452CrossRefPubMedPubMedCentral Felson DT, Cooke TDV, Niu J, Goggins J, Choi J et al (2009) Can anatomic alignment measured from a knee radiograph substitute for mechanical alignment from full limb films? Osteoarthr Cartil 17:1448–1452CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Gibson K, Sayers SP, Minor MA (2009) Accuracy of a non-radiographic method of measuring varus/valgus alignment in knees with osteoarthritis. Mo Med 106:132–135PubMed Gibson K, Sayers SP, Minor MA (2009) Accuracy of a non-radiographic method of measuring varus/valgus alignment in knees with osteoarthritis. Mo Med 106:132–135PubMed
12.
Zurück zum Zitat Hirschmann MT, Konala P, Amsler F, Iranpour F, Friederich NF et al (2011) The position and orientation of total knee replacement components: a comparison of conventional radiographs, transverse 2D-CT slices and 3D-CT reconstruction. J Bone Joint Surg Br 93:629–633CrossRefPubMed Hirschmann MT, Konala P, Amsler F, Iranpour F, Friederich NF et al (2011) The position and orientation of total knee replacement components: a comparison of conventional radiographs, transverse 2D-CT slices and 3D-CT reconstruction. J Bone Joint Surg Br 93:629–633CrossRefPubMed
13.
Zurück zum Zitat Iranpour-Boroujeni T, Li J, Lynch JA, Nevitt M, Duryea J et al (2014) A new method to measure anatomic knee alignment for large studies of OA: data from the osteoarthritis initiative. Osteoarthr Cartil 22:1668–1674CrossRefPubMed Iranpour-Boroujeni T, Li J, Lynch JA, Nevitt M, Duryea J et al (2014) A new method to measure anatomic knee alignment for large studies of OA: data from the osteoarthritis initiative. Osteoarthr Cartil 22:1668–1674CrossRefPubMed
14.
Zurück zum Zitat Jabalameli M, Moradi A, Bagherifard A, Radi M, Mokhtari T (2016) Evaluation of distal femoral rotational alignment with spiral CT scan before total knee arthroplasty (a study in Iranian population). Arch Bone Joint Surg 4:122–127PubMed Jabalameli M, Moradi A, Bagherifard A, Radi M, Mokhtari T (2016) Evaluation of distal femoral rotational alignment with spiral CT scan before total knee arthroplasty (a study in Iranian population). Arch Bone Joint Surg 4:122–127PubMed
15.
Zurück zum Zitat Kawakami H, Sugano N, Yonenobu K, Yoshikawa H, Ochi T et al (2004) Effects of rotation on measurement of lower limb alignment for knee osteotomy. J Orthop Res 22:1248–1253CrossRefPubMed Kawakami H, Sugano N, Yonenobu K, Yoshikawa H, Ochi T et al (2004) Effects of rotation on measurement of lower limb alignment for knee osteotomy. J Orthop Res 22:1248–1253CrossRefPubMed
16.
Zurück zum Zitat Konigsberg B, Hess R, Hartman C, Smith L, Garvin KL (2014) Inter- and intraobserver reliability of two-dimensional CT scan for total knee arthroplasty component malrotation. Clin Orthop Relat Res 472:212–217CrossRefPubMed Konigsberg B, Hess R, Hartman C, Smith L, Garvin KL (2014) Inter- and intraobserver reliability of two-dimensional CT scan for total knee arthroplasty component malrotation. Clin Orthop Relat Res 472:212–217CrossRefPubMed
17.
Zurück zum Zitat Kraus VB, Vail TP, Worrell T, McDaniel G (2005) A comparative assessment of alignment angle of the knee by radiographic and physical examination methods. Arthritis Rheumatol 52:1730–1735CrossRef Kraus VB, Vail TP, Worrell T, McDaniel G (2005) A comparative assessment of alignment angle of the knee by radiographic and physical examination methods. Arthritis Rheumatol 52:1730–1735CrossRef
19.
Zurück zum Zitat Lazennec JY, Chometon Q, Folinais D, Robbins CB, Pour AE (2017) Are advanced three-dimensional imaging studies always needed to measure the coronal knee alignment of the lower extremity? Int Orthop 41:917–924CrossRefPubMed Lazennec JY, Chometon Q, Folinais D, Robbins CB, Pour AE (2017) Are advanced three-dimensional imaging studies always needed to measure the coronal knee alignment of the lower extremity? Int Orthop 41:917–924CrossRefPubMed
20.
Zurück zum Zitat Longstaff LM, Sloan K, Stamp N, Scaddan M, Beaver R (2009) Good alignment after total knee arthroplasty leads to faster rehabilitation and better function. J Arthroplast 24:570–578CrossRef Longstaff LM, Sloan K, Stamp N, Scaddan M, Beaver R (2009) Good alignment after total knee arthroplasty leads to faster rehabilitation and better function. J Arthroplast 24:570–578CrossRef
21.
Zurück zum Zitat Luyckx T, Zambianchi F, Catani F, Bellemans J, Victor J (2013) Coronal alignment is a predictor of the rotational geometry of the distal femur in the osteo-arthritic knee. Knee Surg Sports Traumatol Arthrosc 21:2331–2337CrossRefPubMed Luyckx T, Zambianchi F, Catani F, Bellemans J, Victor J (2013) Coronal alignment is a predictor of the rotational geometry of the distal femur in the osteo-arthritic knee. Knee Surg Sports Traumatol Arthrosc 21:2331–2337CrossRefPubMed
22.
Zurück zum Zitat Moreland JR, Bassett LW, Hanker GJ (1987) Radiographic analysis of the axial alignment of the lower extremity. J Bone Joint Surg Am 69:745–749CrossRefPubMed Moreland JR, Bassett LW, Hanker GJ (1987) Radiographic analysis of the axial alignment of the lower extremity. J Bone Joint Surg Am 69:745–749CrossRefPubMed
23.
Zurück zum Zitat Moyer R, Wirth W, Duryea J, Eckstein F (2016) Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative. Osteoarthr Cartil 24:254–261CrossRefPubMed Moyer R, Wirth W, Duryea J, Eckstein F (2016) Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment: data from the Osteoarthritis Initiative. Osteoarthr Cartil 24:254–261CrossRefPubMed
24.
Zurück zum Zitat Nam D, Maher PA, Robles A, McLawhorn AS, Mayman DJ (2013) Variability in the relationship between the distal femoral mechanical and anatomical axes in patients undergoing primary total knee arthroplasty. J Arthroplast 28:798–801CrossRef Nam D, Maher PA, Robles A, McLawhorn AS, Mayman DJ (2013) Variability in the relationship between the distal femoral mechanical and anatomical axes in patients undergoing primary total knee arthroplasty. J Arthroplast 28:798–801CrossRef
25.
Zurück zum Zitat Parratte S, Pagnano MW, Trousdale RT, Berry DJ (2010) Effect of postoperative mechanical axis alignment on the fifteen-year survival of modern, cemented total knee replacements. J Bone Joint Surg Am 92:2143–2149CrossRefPubMed Parratte S, Pagnano MW, Trousdale RT, Berry DJ (2010) Effect of postoperative mechanical axis alignment on the fifteen-year survival of modern, cemented total knee replacements. J Bone Joint Surg Am 92:2143–2149CrossRefPubMed
26.
Zurück zum Zitat Paternostre F, Schwab P-E, Thienpont E (2014) The difference between weight-bearing and non-weight-bearing alignment in patient-specific instrumentation planning. Knee Surg Sports Traumatol Arthrosc 22:674–679CrossRefPubMed Paternostre F, Schwab P-E, Thienpont E (2014) The difference between weight-bearing and non-weight-bearing alignment in patient-specific instrumentation planning. Knee Surg Sports Traumatol Arthrosc 22:674–679CrossRefPubMed
27.
Zurück zum Zitat Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME et al (2011) The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am 93:1588–1596CrossRefPubMed Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME et al (2011) The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am 93:1588–1596CrossRefPubMed
28.
Zurück zum Zitat Rivière C, Lazic S, Villet L, Wiart Y, Allwood SM et al (2018) Kinematic alignment technique 345 for total hip and knee arthroplasty. EFORT Open Rev 3:98–105CrossRefPubMedPubMedCentral Rivière C, Lazic S, Villet L, Wiart Y, Allwood SM et al (2018) Kinematic alignment technique 345 for total hip and knee arthroplasty. EFORT Open Rev 3:98–105CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat Sailhan F, Jacob L, Hamadouche M (2017) Differences in limb alignment and femoral mechanical–anatomical angles using two dimension versus three dimension radiographic imaging. Int Orthop 41:2009–2016CrossRefPubMed Sailhan F, Jacob L, Hamadouche M (2017) Differences in limb alignment and femoral mechanical–anatomical angles using two dimension versus three dimension radiographic imaging. Int Orthop 41:2009–2016CrossRefPubMed
31.
Zurück zum Zitat Sharma L (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286:188–195CrossRefPubMed Sharma L (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286:188–195CrossRefPubMed
32.
Zurück zum Zitat Slevin O, Hirschmann A, Schiapparelli FF, Amsler F, Huegli RW et al (2018) Neutral alignment leads to higher knee society scores after total knee arthroplasty in preoperatively non-varus patients: a prospective clinical study using 3D-CT. Knee Surg Sports Traumatol Arthrosc 26:1602–1609CrossRefPubMed Slevin O, Hirschmann A, Schiapparelli FF, Amsler F, Huegli RW et al (2018) Neutral alignment leads to higher knee society scores after total knee arthroplasty in preoperatively non-varus patients: a prospective clinical study using 3D-CT. Knee Surg Sports Traumatol Arthrosc 26:1602–1609CrossRefPubMed
33.
Zurück zum Zitat Slevin O, Schmid FA, Schiapparelli F-F, Rasch H, Amsler F et al (2017) Coronal femoral TKA position significantly influences in vivo patellar loading in unresurfaced patellae after primary total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 25:3605–3610CrossRefPubMed Slevin O, Schmid FA, Schiapparelli F-F, Rasch H, Amsler F et al (2017) Coronal femoral TKA position significantly influences in vivo patellar loading in unresurfaced patellae after primary total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 25:3605–3610CrossRefPubMed
34.
Zurück zum Zitat Than P, Szuper K, Somoskeöy S, Warta V, Illés T (2012) Geometrical values of the normal and arthritic hip and knee detected with the EOS imaging system. Int Orthop 36:1291–1297CrossRefPubMed Than P, Szuper K, Somoskeöy S, Warta V, Illés T (2012) Geometrical values of the normal and arthritic hip and knee detected with the EOS imaging system. Int Orthop 36:1291–1297CrossRefPubMed
35.
Zurück zum Zitat Thienpont E, Schwab P-E, Paternostre F, Koch P (2014) Rotational alignment of the distal femur: anthropometric measurements with CT-based patient-specific instruments planning show high variability of the posterior condylar angle. Knee Surg Sports Traumatol Arthrosc 22:2995–3002CrossRefPubMed Thienpont E, Schwab P-E, Paternostre F, Koch P (2014) Rotational alignment of the distal femur: anthropometric measurements with CT-based patient-specific instruments planning show high variability of the posterior condylar angle. Knee Surg Sports Traumatol Arthrosc 22:2995–3002CrossRefPubMed
36.
Zurück zum Zitat Vanlommel L, Vanlommel J, Claes S, Bellemans J (2013) Slight undercorrection following total knee arthroplasty results in superior clinical outcomes in varus knees. Knee Surg Sports Traumatol Arthrosc 21:2325–2330CrossRefPubMed Vanlommel L, Vanlommel J, Claes S, Bellemans J (2013) Slight undercorrection following total knee arthroplasty results in superior clinical outcomes in varus knees. Knee Surg Sports Traumatol Arthrosc 21:2325–2330CrossRefPubMed
37.
Zurück zum Zitat Weinberg DS, Tucker BJ, Drain JP, Wang DM, Gilmore A et al (2016) A cadaveric investigation into the demographic and bony alignment properties associated with osteoarthritis of the patellofemoral joint. Knee 23:350–356CrossRefPubMed Weinberg DS, Tucker BJ, Drain JP, Wang DM, Gilmore A et al (2016) A cadaveric investigation into the demographic and bony alignment properties associated with osteoarthritis of the patellofemoral joint. Knee 23:350–356CrossRefPubMed
38.
Zurück zum Zitat Willcox NMJ, Clarke JV, Smith BRK, Deakin AH, Deep K (2012) A comparison of radiological and computer navigation measurements of lower limb coronal alignment before and after total knee replacement. J Bone Joint Surg Br 94-B:1234–1240CrossRef Willcox NMJ, Clarke JV, Smith BRK, Deakin AH, Deep K (2012) A comparison of radiological and computer navigation measurements of lower limb coronal alignment before and after total knee replacement. J Bone Joint Surg Br 94-B:1234–1240CrossRef
39.
Zurück zum Zitat Zhang Y, Wang X, Shao Y, Xia Q (2018) The orientation of the surgical epicondylar axis varies in varus and non-varus knees in the coronal plane. Knee Surg Sports Traumatol Arthrosc 26:2580–2586CrossRefPubMed Zhang Y, Wang X, Shao Y, Xia Q (2018) The orientation of the surgical epicondylar axis varies in varus and non-varus knees in the coronal plane. Knee Surg Sports Traumatol Arthrosc 26:2580–2586CrossRefPubMed
Metadaten
Titel
Highly variable coronal tibial and femoral alignment in osteoarthritic knees: a systematic review
verfasst von
Silvan Hess
Lukas B. Moser
Felix Amsler
Henrik Behrend
Michael T. Hirschmann
Publikationsdatum
15.04.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 5/2019
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-019-05506-2

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