Erschienen in:
01.06.2007 | Brief Report
Is there a role for rituximab in the treatment of idiopathic childhood nephrotic syndrome?
verfasst von:
Graham C. Smith
Erschienen in:
Pediatric Nephrology
|
Ausgabe 6/2007
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Abstract
We each have nephrotic patients who become steroid dependent and in whom multiple immunosuppressive agents are employed. There is a need to balance possible therapeutic benefits with drug toxicity. This case report describes such a patient, who has suffered from nephrotic syndrome for over 11 years and had become resistant to the usual therapies. He was therefore given a single dose of the anti-CD20 drug rituximab, to which he showed a prompt response, leaving him free of proteinuria for the past 10 months.