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Erschienen in: Surgery Today 9/2020

29.08.2019 | Review Article

Management of isolated para-aortic lymph node recurrence of colorectal cancer

verfasst von: Kazuhito Sasaki, Hiroaki Nozawa, Kazushige Kawai, Keisuke Hata, Toshiaki Tanaka, Takeshi Nishikawa, Yasutaka Shuno, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Hirofumi Sonoda, Soichiro Ishihara

Erschienen in: Surgery Today | Ausgabe 9/2020

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Abstract

Isolated para-aortic lymph node recurrence (PALNR) after curative surgery for colorectal cancer (CRC) is rare and its optimal management is not defined clearly. This review investigates the best outcomes among published studies on the management of PALNR in the field of CRC. We searched the PubMed database for studies reporting on the management of isolated PALNR in CRC, published in English or Japanese from January, 2000 to December, 2018. Studies including patients with other metastases were excluded. A total of 24 retrospective studies including 227 patients with PALNR were evaluated. The 3-year overall survival (OS) ranged from 60 to 100%, with a median OS of 34–80 months for patients who underwent PALNR dissection, and 14–42 months for patients who received non-surgical treatment. No surgery-related mortality was reported and the incidence of surgical, mainly low-grade, complications ranged from 33 to 52%. The predictors of improved survival outcome included R0 resection margins. Dissection for PALNR from CRC is considered a feasible treatment option that may yield a better prognosis than non-surgical treatment alone. Preoperative chemotherapy or CRT should be considered for their potential benefits, including a reduction in cancer volume and improved R0 resection rates.
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Metadaten
Titel
Management of isolated para-aortic lymph node recurrence of colorectal cancer
verfasst von
Kazuhito Sasaki
Hiroaki Nozawa
Kazushige Kawai
Keisuke Hata
Toshiaki Tanaka
Takeshi Nishikawa
Yasutaka Shuno
Manabu Kaneko
Koji Murono
Shigenobu Emoto
Hirofumi Sonoda
Soichiro Ishihara
Publikationsdatum
29.08.2019
Verlag
Springer Singapore
Erschienen in
Surgery Today / Ausgabe 9/2020
Print ISSN: 0941-1291
Elektronische ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-019-01872-z

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