nach oben

Head and Neck Pathology

Erschienen in:

01.06.2013 | Case Report

The Non-ossifying Fibroma: A Case Report and Review of the Literature

verfasst von: Leah M. Bowers, Donald M. Cohen, Indraneel Bhattacharyya, James C. Pettigrew Jr., Mary F. Stavropoulos

Erschienen in: Head and Neck Pathology | Ausgabe 2/2013

Einloggen, um Zugang zu erhalten

Abstract

The non-ossifying fibroma (NOF) is a benign, non-neoplastic lesion most commonly seen in the metaphyses of the long bones in children. While rare, the NOF has been reported in the mandible. The NOF in the extra-gnathic skeleton has a characteristic radiographic appearance, is typically asymptomatic and has a variable histologic make-up. Correlation of the radiographic appearance, clinical presentation and histopathology allows for differentiation of the NOF from odontogenic and non-odontogenic cysts and tumors. We report a new case of this interesting entity and review the radiographic, clinical and histologic features of the gnathic NOF reported in the literature. A thorough search of the English language literature returned a total of 19 cases of NOF involving the gnathic bones.

Sontag LW, Pyle DI. The appearance and nature of cyst-like areas in distal femoral metaphyses of children. Am J Roentgenol Radiat Ther. 1941;46:185–8.

Jaffe HL, Lichtenstein L. Non-osteogenic fibroma of bone. Am J Pathol. 1942;18:205–20.PubMed

Schajowicz F, Ackerman LV, Sissons HA, et al. International histological classification of tumors (histological typing of bone tumors). Geneva: World Health Organization; 1993.CrossRef

Mizukawa N, Nishijima Y, Nishijima K. Metaphyseal fibrous defect (non-ossifying fibroma) in the mandible. A case report. Int J Oral Maxillofac Surg. 1997;26:129–30.PubMedCrossRef

Chrcanovic B, Albanese AL, Freire-Maia B, et al. Non-ossifying fibroma (metaphyseal fibrous defect) of the mandible. Oral Maxillofac Surg. 2011;4:233–7.CrossRef

Fletcher CDM, Unni KK, Mertens F. World Health Organization: classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press; 2002.

Dahlin DC. Fibroma (nonosteogenic fibroma of bone, metaphyseal fibrous defect), myxoma, cortical desmoid, fibromatosis, and “Xanthoma”. In: Thomas CC, editor. Bone tumors. general aspects and data on 6,221 cases, 3rd ed. Springfield, IL: Charles C Thomas; 1978. p. 122–36.

Betsy M, Kupersmith LM, Springfield DS. Metaphyseal fibrous defects. J Am Acad Orthop Surg. 2004;12:89–95.PubMed

Glockenberg A, Sobel E, Noel JF. Nonossifying fibroma. Four cases and review of the literature. J Am Podiatr Med Assoc. 1997;87(2):66–9.PubMed

10.

Hudson JW, Livesay KW, McCoy JM. Condylar lesion. J Oral Maxillofac Surg. 2003;61:824–6.PubMedCrossRef

11.

Park JK, Levy BA, Hanley JB. Non-ossifying fibroma of the mandible: report of a case. J Baltim Coll Dent Surg. 1982;35:1–5.

12.

Liaw WJ, So TK, Yao YT. Non-ossifying fibroma of mandible. A case report. J Formos Med Assoc. 1979;78:795–802.

13.

Blau RA, Zwick DL, Westphal RA. Multiple non-ossifying fibromas. A case report. J Bone Joint Surg Am. 1988;70:299–304.PubMed

14.

Shaffer LG, Tommerup N, editors. ISCN 2005: an international system for human cytogenetic nomenclature. Basel: S. Karger; 2005.

15.

Brassesco MS, Valera ET, Engel EE, et al. Clonal complex chromosome aberration in non-ossifying fibroma. Pediatr Blood Cancer. 2010;54:764–7.PubMed

16.

Makek M. Non-ossifying fibroma of the mandible. A common lesion with unusual location. Arch Orthop Trauma Surg. 1980;96:225–7.PubMedCrossRef

17.

Quinn JH, Graves LR, Leonard GI. Unusual histiocytic lesion of the mandible: report of a case. J Oral Surg. 1970;28:528–30.PubMed

18.

Ide F, Kusuhara S, Onuma H, et al. Xanthic variant of the non-ossifying fibroma (so called xanthofibroma) of the mandible: an ultrastructural study. Acta Pathol Jpn. 1982;32:135–42.PubMed

19.

Elzay RP, Mills S, Kay S. Fibrous defect (non-ossifying fibroma) of the mandible. Oral Surg Oral Med Oral Pathol. 1984;58:402–7.PubMedCrossRef

20.

Aldred MJ, Breckon JJW, Holland CS. Non-osteogenic fibroma of the mandibular condyle. Br J Oral Maxillofac Surg. 1989;27:412–6.PubMedCrossRef

21.

Rudy HN, Scheingold SS. Solitary xanthogranuloma of the mandible. Report of a case. Oral Surg Oral Med Oral Pathol. 1964;18:262–71.PubMedCrossRef

22.

Bessho K, Murakami K, Nishida M, et al. Non-ossifying fibroma of the mandible: case report and review of literature. Jpn J Oral Maxillofac Surg. 1986;32:291–6.CrossRef

23.

Huvos AG. Nonossifying Fibroma. In: Bone tumors: diagnosis, treatment, and prognosis. Philadelphia, PA: W. B. Saunders; 1979. p. 297–306.

24.

Bailey JS, Nikitakis NG, Lopes M, et al. Non-ossifying fibroma of the mandible in a 6-year-old girl: a case report and review of the literature. J Oral Maxillofac Surg. 2001;59:815–8.PubMedCrossRef

25.

Uçkan S, Gürol M, Mutlu N, et al. Non-ossifying fibroma of the mandible: report of a case. Br J Oral Maxillofac Surg. 1999;37:152–4.PubMed

26.

Spjut HJ, Dorfman HD, Fechner RE, Ackerman LV. Tumors of bone and cartilage. In: Atlas of tumor pathology, second series, fascicle 5. Washington: Armed Forces Institute of Pathology; 197l. p. 249–50.

27.

Harsanyi BB, Larsson A. Xanthomatous lesions of the mandible: osseous expression of non-X histiocytosis and benign fibrous histiocytoma. Oral Surg Oral Med Oral Pathol. 1988;65(5):551–66.PubMedCrossRef

28.

Mirra JM. Fibrohistiocytic tumors intramedullary origin. In: Mirra JM, editor. Bone tumors: clinical, radiologic, and pathologic correlation. Philadelphia: Lea & Febiger; 1989. p. 692–731.

29.

Hatcher CH. The pathogenesis of localized fibrous lesions in the metaphyses of long bones. Ann Surg. 1945;122:1016.CrossRef

30.

Bhagwandeen SB. Malignant transformation of a non-osteogenic fibroma of bone. J Pathol. 1966;92:562–4.CrossRef

31.

Heo MS, Cho HJ, Kwon KJ, et al. Benign fibrous histiocytoma in the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:276–80.PubMedCrossRef

32.

Neville B, Damm D, Allen C, Bouquot J. Oral & maxillofacial pathology. 3rd ed. Philadelphia: Saunders; 2009. p. 729–31.

33.

Roche WC, Krishnan V, McDaniel RK. Fibrous defect of the mandible: a case report and literature review. J Oral Maxillofac Surg. 1993;51:809–11.PubMedCrossRef

34.

Fechner RE, Mills SE. Tumors of the bone and joints. In: Rosai J, Sobin LH, editors. Atlas of tumor pathology, 3rd series, 8th fascicle. Washington: AFIP; 1993. p. 129–44.

35.

Hamada T, Ito H, Araki Y, et al. Benign fibrous histiocytoma of the femur: review of three cases. Skeletal Radiol. 1996;25:25–9.PubMedCrossRef

36.

Campanacci M, Laus M, Boriani S. Multiple non-ossifying fibromata with extraskeletal anomalies: a new syndrome? J Bone Joint Surg Br. 1983;65:627–32.PubMed

37.

Mirra JM, Gold RH, Rand F. Disseminated non-ossifying fibromas in association with café-au-lait spots (Jaffe-Campanacci syndrome). Clin Orthop Relat Res. 1982;168:192–205.PubMed

38.

Abdelsayed RA, Sharma S, Ferguson H. Fibrous cortical defect (nonossifying fibroma) of the mandibular ramus: report of 2 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:504–8.PubMedCrossRef

Titel: The Non-ossifying Fibroma: A Case Report and Review of the Literature
verfasst von: Leah M. Bowers
Donald M. Cohen
Indraneel Bhattacharyya
James C. Pettigrew Jr.
Mary F. Stavropoulos
Publikationsdatum: 01.06.2013
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 2/2013
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-012-0399-7

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

The Non-ossifying Fibroma: A Case Report and Review of the Literature

Abstract

Neu im Fachgebiet Pathologie

Assistierter Suizid durch Infusion von Thiopental

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2013

Sclerosing Rhabdomyosarcoma: Report of a Case Arising in the Head and Neck of an Adult and Review of the Literature

A Case of Age-Related Epstein–Barr Virus (EBV)-Associated B Cell Lymphoproliferative Disorder, so-called Polymorphous Subtype, of the Mandible, with a Review of the Literature

Carcinosarcoma ex Non-Recurrent Pleomorphic Adenoma Composed of TTF-1 Positive Large Cell Neuroendocrine Carcinoma and Myofibrosarcoma: Apropos a Rare Case

Oral Atypical Cellular Blue Nevus: An Infiltrative Melanocytic Proliferation

B7-H1 Expression Model for Immune Evasion in Human Papillomavirus-Related Oropharyngeal Squamous Cell Carcinoma

The Significance of Surface Ulceration as a Sign of Malignancy in Exophytic Oral Mucosal Lesions: Myth or Fact?

Neu im Fachgebiet Pathologie

Assistierter Suizid durch Infusion von Thiopental

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren