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Die Anaesthesiologie

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01.07.2014 | Intensivmedizin

Neue KDIGO-Leitlinien zur akuten Nierenschädigung

Praktische Handlungsempfehlungen

verfasst von: Prof. Dr. A. Zarbock, S. John, A. Jörres, D. Kindgen-Milles

Erschienen in: Die Anaesthesiologie | Ausgabe 7/2014

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Zusammenfassung

Die akute Nierenschädigung („acute kidney injury“, AKI) hat bei kritisch kranken Patienten eine hohe Inzidenz und geht mit einer signifikant erhöhten Morbidität und Mortalität im Kurz- und Langzeitverlauf einher. Im Jahr 2012 wurden die KDIGO-Leitlinien (Kidney Disease Improving Global Outcome, KDIGO) publiziert, in denen evidenzbasierte praktische Empfehlungen zur Behandlung von Patienten mit AKI gegeben werden. Der 1. Teil der Leitlinien befasst sich mit der Vereinheitlichung von bisherigen Definitionen sowie der Schweregradeinteilung der AKI. In den weiteren Abschnitten wird unter Berücksichtigung der vorhandenen Evidenz auf Prävention, medikamentöse Therapie und Nierenersatztherapie bei Patienten mit AKI eingegangen. In jedem Abschnitt wird nach Darstellung der aktuellen Datenlage eine klare und gewichtete Behandlungsempfehlung ausgesprochen. Bei Nichtverfügbarkeit von spezifischen medikamentösen Therapien sind die wesentlichen Pfeiler einer effektiven Behandlung die frühe Diagnostik, die Vermeidung von Nephrotoxinen, eine aggressive hämodynamische Optimierung unter strikter Kontrolle des Volumenstatus sowie letztlich eine effektive, aber schonende Nierenersatztherapie.

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Titel: Neue KDIGO-Leitlinien zur akuten Nierenschädigung
Praktische Handlungsempfehlungen
verfasst von: Prof. Dr. A. Zarbock
S. John
A. Jörres
D. Kindgen-Milles
Publikationsdatum: 01.07.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Die Anaesthesiologie / Ausgabe 7/2014
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI: https://doi.org/10.1007/s00101-014-2344-5

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