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01.07.2010 | Short Communication

Analysis of 21 X-chromosomal STRs in an Algerian population sample

verfasst von: Asmahan Bekada, Soraya Benhamamouch, Abdallah Boudjema, Mustapha Fodil, Silvia Menegon, Carlo Torre, Carlo Robino

Erschienen in: International Journal of Legal Medicine | Ausgabe 4/2010

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Abstract

Twenty-one X-chromosomal short tandem repeat loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10074-DXS10079 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423-DXS10011 (Xq28), and the loci DXS6800 and GATA172D05 were typed in a northwestern Algerian population sample (n = 210; 104 men and 106 women). Allele and haplotype frequencies were calculated. No evidence of linkage disequilibrium was observed between pairs of loci within clusters of linked markers. At locus DXS10148, sequence analysis of a subset of alleles displaying unusual amplicon length (≥ 36 repeat units) and anomalous electrophoretic mobility showed that this marker has a complex molecular structure with different repeat variants within alleles of identical amplicon size.

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Titel: Analysis of 21 X-chromosomal STRs in an Algerian population sample
verfasst von: Asmahan Bekada
Soraya Benhamamouch
Abdallah Boudjema
Mustapha Fodil
Silvia Menegon
Carlo Torre
Carlo Robino
Publikationsdatum: 01.07.2010
Verlag: Springer-Verlag
Erschienen in: International Journal of Legal Medicine / Ausgabe 4/2010
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-009-0397-9

Springer Medizin

Analysis of 21 X-chromosomal STRs in an Algerian population sample

Abstract

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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