nach oben

Erschienen in:

21.04.2018 | Original Paper

Treatment Outcomes Associated with Quitting Cigarettes Among Sexual Minority Men Living with HIV: Antiretroviral Adherence, Engagement in Care, and Sustained HIV RNA Suppression

verfasst von: Dana King, Chris Grasso, Lydia Dant, Steven A. Elsesser, Heidi M. Crane, Karen L. Cropsey, Kenneth H. Mayer, Conall O’Cleirigh

Erschienen in: AIDS and Behavior | Ausgabe 9/2018

Einloggen, um Zugang zu erhalten

Abstract

Cigarette smoking is particularly harmful for sexual minority men living with HIV. This study aimed to find benefits of quitting by examining relationships between smoking and sustained HIV RNA suppression, recent CD4 count, ART medication adherence, and engagement in HIV medical care. Sexual minority men (n = 346), former or current smokers, received HIV care at a community health center. Survey responses were combined with electronic health record data in adjusted regression models. Most patients were Caucasian (87%) and 148 (46%) had incomes below the poverty level and 80% had sustained HIV RNA suppression. Compared to current smokers, former smokers had increased odds of sustaining HIV RNA suppression (OR 1.89; 95% CI 1.02–3.48) of reporting > 90% adherence (OR 2.25; 95% CI 1.21–4.17), and were less likely to miss appointments (OR 0.37; 95% CI 0.17–0.82). Heavier smokers (OR 0.36; 95% CI 0.17–0.77) and patients who smoked the longest (OR 0.31; 95% CI 0.14–0.68) had reduced odds of sustaining HIV RNA suppression. Smoking assessment, treatment, and referral could augment HIV outcomes for sexual minority men with HIV.

U.S. Department of Health and Human Services (USDHHS). The health consequences of smoking: 50 years of progress. A Report of the Surgeon General. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. 2014.

Baggett TP, Lebrun-Harris LA, Rigotti NA. Homelessness, cigarette smoking and desire to quit: results from a US national study. Addiction. 2013;108:2009–18.CrossRefPubMedPubMedCentral

Tessaro I, Lyna PR, Rimer BK, et al. Readiness to change smoking behavior in a community health center population. J Community Health. 1997;22:15–31.CrossRefPubMed

Lifson AR, Neuhaus J, Arribas JR, et al. Smoking-related health risks among persons with HIV in the strategies for management of antiretroviral therapy clinical trial. Am J Public Health. 2010;100:1896–903.CrossRefPubMedPubMedCentral

O’Cleirigh C, Valentine SE, Pinkston M, et al. The unique challenges facing HIV-positive patients who smoke cigarettes: HIV viremia, ART adherence, engagement in HIV care, and concurrent substance use. AIDS Behav. 2015;19:178–85.CrossRefPubMedPubMedCentral

Pines H, Koutsky L, Buskin S. Cigarette smoking and mortality among HIV-infected individuals in Seattle, Washington (1996–2008). AIDS Behav. 2011;15:243–51.CrossRefPubMed

Tesoriero JM, Gieryic SM, Carrascal A, et al. Smoking among HIV positive New Yorkers: prevalence, frequency, and opportunities for cessation. AIDS Behav. 2010;14:824–35.CrossRefPubMed

Webb MS, Vanable PA, Carey MP, et al. Cigarette smoking among HIV + men and women: examining health, substance use, and psychosocial correlates across the smoking spectrum. J Behav Med. 2007;30:371–83.CrossRefPubMedPubMedCentral

Halloran J. Increasing survival with HIV: impact on nursing care. AACN Clin Issues. 2006;17:8–17.CrossRefPubMed

10.

Engels EA, Brock MV, Chen J, et al. Elevated incidence of lung cancer among HIV-infected individuals. J Clin Oncol. 2006;24:1383–8.CrossRefPubMed

11.

Lifson AR, Lando HA. Smoking and HIV: prevalence, health risks, and cessation strategies. Curr HIV/AIDS Rep. 2012;9:223–30.CrossRefPubMed

12.

Miguez-Burbano MJ, Burbano X, Ashkin D, et al. Impact of tobacco use on the development of opportunistic respiratory infections in HIV seropositive patients on antiretroviral therapy. Addict Biol. 2003;8:39–43.CrossRefPubMed

13.

De Socio GV, Martinelli L, Morosi S, et al. Is estimated cardiovascular risk higher in HIV-infected patients than in the general population? Scand J Infect Dis. 2007;39:805–12.CrossRefPubMed

14.

De Socio GV, Parruti G, Quirino T, et al. Identifying HIV patients with an unfavorable cardiovascular risk profile in the clinical practice: results from the SIMONE study. J Infect. 2008;57:33–40.CrossRefPubMed

15.

Browning KK, Wewers ME, Ferketich AK, et al. Tobacco use and cessation in HIV-infected individuals. Clin Chest Med. 2013;34:181–90.CrossRefPubMedPubMedCentral

16.

Petrache I, Diab K, Knox KS, et al. HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism. Thorax. 2008;63:463–9.CrossRefPubMed

17.

Cui Q, Carruthers S, McIvor A, et al. Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study. AIDS Res Ther. 2010;7:6.CrossRefPubMedPubMedCentral

18.

van Zyl Smit RN, Pai M, Yew WW, et al. Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD. Eur Respir J. 2010;35:27–33.CrossRefPubMedPubMedCentral

19.

Winstone TA, Man SF, Hull M, et al. Epidemic of lung cancer in patients with HIV infection. Chest. 2013;143:305–14.CrossRefPubMedPubMedCentral

20.

De P, Farley A, Lindson N, et al. Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV. BMC Med. 2013;11:15.CrossRefPubMedPubMedCentral

21.

Cropsey KL, Willig JH, Mugavero MJ, et al. Cigarette smokers are less likely to have undetectable viral loads: results from four HIV clinics. J Addict Med. 2016;10:13–9.CrossRefPubMedPubMedCentral

22.

Peretti-Watel P, Spire B, Lert F, et al. Drug use patterns and adherence to treatment among HIV-positive patients: evidence from a large sample of French outpatients (ANRS-EN12-VESPA 2003). Drug Alcohol Depend. 2006;82(Suppl 1):S71–9.CrossRefPubMed

23.

Shuter J, Bernstein SL. Cigarette smoking is an independent predictor of nonadherence in HIV-infected individuals receiving highly active antiretroviral therapy. Nicotine Tob Res. 2008;10:731–6.CrossRefPubMed

24.

Gardner EM, McLees MP, Steiner JF, et al. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis. 2011;52:793–800.CrossRefPubMedPubMedCentral

25.

Traeger L, O’Cleirigh C, Skeer MR, et al. Risk factors for missed HIV primary care visits among men who have sex with men. J Behav Med. 2012;35:548–56.CrossRefPubMed

26.

Cashman SB, Savageau JA, Lemay CA, et al. Patient health status and appointment keeping in an urban community health center. J Health Care Poor Underserved. 2004;15:474–88.CrossRefPubMed

27.

Mugavero MJ, Amico KR, Westfall AO, et al. Early retention in HIV care and viral load suppression: implications for a test and treat approach to HIV prevention. J Acquir Immune Defic Syndr. 2012;59:86–93.CrossRefPubMedPubMedCentral

28.

Hile S, Feldman M, Alexy E, Irvine M. Recent tobacco smoking is associated with poor HIV medical outcomes among HIV-infected individuals in New York. AIDS Behav. 2016;20(8):1722–9.CrossRefPubMedPubMedCentral

29.

Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol. 2002;2(5):372–7.CrossRefPubMed

30.

Kalra R, Singh S, Savage S, Finch G, Sopori M. Effects of cigarette smoke on immune response: chronic exposure to cigarette smoke impairs antigen-mediated signaling in T cells and depletes IP3-sensitive Ca(2 +) stores. J Pharmacol Exp Ther. 2000;293(1):166–71.PubMed

31.

Batchelder A, Brisbane M, Litwin A, Nahvi S, Berg K, Arnsten J. “Damaging what wasn’t damaged already”: psychological tension and antiretroviral adherence among HIV-infected methadone-maintained drug users. AIDS Care. 2013;25(11):1370–4.CrossRefPubMed

32.

Batchelder A, Peyser D, Nahvi S, Arnsten J, Litwin A. Hepatitis C treatment turned me around: psychological and behavioral transformation related to hepatitis C treatment. Drug Alcohol Depend. 2015;153:66–71.CrossRefPubMedPubMedCentral

33.

Centers for Disease Control and Prevention. HIV among Gay and Bisexual and men. 2010. https://www.cdc.gov/hiv/pdf/group/msm/cdc-hiv-msm.pdf. Accessed 26 Oct 2017.

34.

King BA, Dube SR, Tynan MA. Current tobacco use among adults in the United States: findings from the national adult tobacco survey. Am J Public Health. 2012;102(11):e93–100.CrossRefPubMedPubMedCentral

35.

Lee JGL, Griffin GK, Melvin CL. Tobacco use among sexual minorities in the USA, 1987 to May 2007: a systematic review. Tob Control. 2009;18(4):275–82.CrossRefPubMed

36.

Burgess D, Lee R, Tran A, Van Ryn M. Effects of perceived discrimination on mental health and mental health services utilization among gay, lesbian, bisexual and transgender persons. J LGBT Health Res. 2008;3(4):1–14.CrossRef

37.

Hatzenbuehler ML, Wieringa NF, Keyes KM. Community-level determinants of tobacco use disparities in lesbian, gay, and bisexual youth: results from a population-based study. Arch Pediatr Adolesc Med. 2011;165(6):527–32.CrossRefPubMed

38.

Bontempo DE, D’Augelli AR. Effects of at-school victimization and sexual orientation on lesbian, gay, or bisexual youths’ health risk behavior. J Adolesc Health. 2002;30(5):364–74.CrossRefPubMed

39.

Willoughby BLB, Doty ND, Malik NM. Victimization, family rejection, and outcomes of gay, lesbian, and bisexual young people: the role of negative GLB identity. J GLBT Fam Stud. 2010;6(4):403–24.CrossRef

40.

Case P, Bryn Austin S, Hunter DJ, et al. Sexual orientation, health risk factors, and physical functioning in the nurses’ Health Study II. J Womens Health. 2004;13(9):1033–47.CrossRef

41.

Blosnich J, Jarrett T, Horn K. Disparities in smoking and acute respiratory illnesses among sexual minority young adults. Lung. 2010;188(5):401–7.CrossRefPubMed

42.

Landers SJ, Mimiaga MJ, Conron KJ. Sexual orientation differences in asthma correlates in a population-based sample of adults. Am J Public Health. 2011;101(12):2238–41.CrossRefPubMedPubMedCentral

43.

Heck JE, Jacobson JS. Asthma diagnosis among individuals in same-sex relationships. J Asthma. 2006;43(8):579–84.CrossRefPubMed

44.

Kitahata MM, Rodriguez B, Haubrich R, et al. Cohort profile: the centers for AIDS research network of integrated clinical systems. Int J Epidemiol. 2008;37:948–55.CrossRefPubMedPubMedCentral

45.

Crane HM, Lober W, Webster E, et al. Routine collection of patient-reported outcomes in an HIV clinic setting: the first 100 patients. Curr HIV Res. 2007;5:109–18.CrossRefPubMed

46.

Amico KR, Fisher WA, Cornman DH, Shuper PA, Redding CG, Konkle-Parker DJ, Barta W, Fisher JD. Visual analog scale of ART adherence: association with 3-day self-report and adherence barriers. J Acquir Immune Defic Syndr. 2006;42(4):455–9.CrossRefPubMed

47.

Simoni JM, Kurth AE, Pearson CR, Pantalone DW, Merrill JO, Frick PA. Self-report measures of antiretroviral therapy adherence: a review with recommendations for HIV research and clinical management. AIDS Behav. 2006;10(3):227–45.CrossRefPubMedPubMedCentral

48.

Gordon L, Gharibian D, Chong K, Chun H. Comparison of HIV virologic failure rates between patients with variable adherence to three antiretroviral regimen types. AIDS Patient Care Stds. 2015;29(7):384–8.CrossRefPubMed

49.

DHHS. Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Washington, DC: US Department of Health and Human Services. 2010. http://AIDSinfo.nih.gov.

50.

Deeks SG, Walker BD. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity. 2007;27:406–16.CrossRefPubMed

51.

Crothers K, Griffith TA, McGinnis KA, et al. The impact of cigarette smoking on mortality, quality of life, and comorbid illness among HIV-positive veterans. J Gen Intern Med. 2005;20:1142–5.CrossRefPubMedPubMedCentral

52.

Wojna V, Robles L, Lasalde-Dominicci J, et al. Associations of cigarette smoking with viral immune and cognitive function in human immunodeficiency virus-seropositive women. J Neurovirol. 2007;13(6):561–8.CrossRefPubMedPubMedCentral

53.

Williams EC, Bradley KA, Balderson BH, et al. Alcohol and associated characteristics among older persons living with human immunodeficiency virus on antiretroviral therapy. Subst Abus. 2014;35:245–53.CrossRefPubMedPubMedCentral

54.

De Boni RB, Zheng L, Rosenkranz SL, et al. Binge drinking is associated with differences in weekday and weekend adherence in HIV-infected individuals. Drug Alcohol Depend. 2016;159:174–80.CrossRefPubMed

55.

Mohammed H, Kieltyka L, Richardson-Alston G, et al. Adherence to HAART among HIV-infected persons in rural Louisiana. AIDS Patient Care STDS. 2004;18:289–96.CrossRefPubMed

56.

Skeer MR, Mimiaga MJ, Mayer KH, et al. Patterns of substance use among a large urban cohort of HIV-infected men who have sex with men in primary care. AIDS Behav. 2012;16:676–89.CrossRefPubMedPubMedCentral

57.

Treisman G, Angelino A. Interrelation between psychiatric disorders and the prevention and treatment of HIV infection. Clin Infect Dis. 2007;45(Suppl 4):S313–7.CrossRefPubMed

58.

Bing EG, Burnam MA, Longshore D, et al. Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. Arch Gen Psychiatry. 2001;58:721–8.CrossRefPubMed

59.

King RM, Vidrine DJ, Danysh HE, et al. Factors associated with nonadherence to antiretroviral therapy in HIV-positive smokers. AIDS Patient Care STDS. 2012;26:479–85.CrossRefPubMed

60.

Glass TR, Battegay M, Cavassini M, et al. Longitudinal analysis of patterns and predictors of changes in self-reported adherence to antiretroviral therapy: swiss HIV Cohort Study. J Acquir Immune Defic Syndr. 2010;54:197–203.PubMed

61.

Taniguchi T, Shacham E, Onen NF, et al. Depression severity is associated with increased risk behaviors and decreased CD4 cell counts. AIDS Care. 2014;26:1004–12.CrossRefPubMedPubMedCentral

62.

Sin NL, DiMatteo MR. Depression treatment enhances adherence to antiretroviral therapy: a meta-analysis. Ann Behav Med. 2014;47:259–69.CrossRefPubMedPubMedCentral

63.

Bondy SJ, Victor JC, Diemert LM. Origin and use of the 100 cigarette criterion in tobacco surveys. Tob Control. 2009;18:317–23.CrossRefPubMed

64.

Balaji A, Bowles K, Le B, Paz-Bailey G, Oster A. High HIV incidence and prevalence and associated factors among young MSM. AIDS. 2008;27(2):269–78.CrossRef

65.

Gerend M, Newcomb M, Mustanski B. Prevalence and correlates of smoking and e-cigarette use among young men who have sex with men and transgender women. Drug Alcohol Depend. 2017;179:395–9.CrossRefPubMedPubMedCentral

66.

Easton A, Jackson K, Mowery P, Comeau D, Sell R. Adolescent same-sex and both-sex romantic attractions and relationships: implications for smoking. Am J Public Health. 2008;98:462–7.CrossRefPubMedPubMedCentral

67.

Austin SB, Ziyadeh N, Fisher LB, et al. Sexual orientation and tobacco use in a cohort study of US adolescent girls and boys. Arch Pediatr Adolesc Med. 2004;158:317–22.CrossRefPubMed

68.

Humfleet GL, Hall SM, Delucchi KL, et al. A randomized clinical trial of smoking cessation treatments provided in HIV clinical care settings. Nicotine Tob Res. 2013;15:1436–45.CrossRefPubMedPubMedCentral

69.

Krebs P, Tseng TY, Pham H, et al. Formative evaluation of a text messaging intervention to promote varenicline adherence among tobacco-dependent persons with HIV. J Health Commun. 2015;20:1021–5.CrossRefPubMed

70.

Vidrine DJ, Marks RM, Arduino RC, et al. Efficacy of cell phone-delivered smoking cessation counseling for persons living with HIV/AIDS: 3-month outcomes. Nicotine Tob Res. 2012;14:106–10.CrossRefPubMed

71.

Aveyard P, Begh R, Parsons A, et al. Brief opportunistic smoking cessation interventions: a systematic review and meta-analysis to compare advice to quit and offer of assistance. Addiction. 2012;107:1066–73.CrossRefPubMed

72.

Webster PC. United States to compel physicians to make “meaningful use” of electronic health records. CMAJ. 2010;182(14):1500. https://doi.org/10.1503/cmaj.109-3361.CrossRefPubMedPubMedCentral

73.

Bae J, Ford EW, Huerta TR. The electronic medical record’s role in support of smoking cessation activities. Nicotine Tob Res. 2016;18(5):1019–24.CrossRefPubMed

Titel: Treatment Outcomes Associated with Quitting Cigarettes Among Sexual Minority Men Living with HIV: Antiretroviral Adherence, Engagement in Care, and Sustained HIV RNA Suppression
verfasst von: Dana King
Chris Grasso
Lydia Dant
Steven A. Elsesser
Heidi M. Crane
Karen L. Cropsey
Kenneth H. Mayer
Conall O’Cleirigh
Publikationsdatum: 21.04.2018
Verlag: Springer US
Erschienen in: AIDS and Behavior / Ausgabe 9/2018
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-018-2116-3

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Treatment Outcomes Associated with Quitting Cigarettes Among Sexual Minority Men Living with HIV: Antiretroviral Adherence, Engagement in Care, and Sustained HIV RNA Suppression

Abstract

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Chronische Verstopfung: „Versuchen Sie es mit grünen Kiwis!“

Blutdrucksenkung könnte Uterusmyome verhindern

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

Update Innere Medizin

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 9/2018

Social Capital, Depressive Symptoms, and HIV Viral Suppression Among Young Black, Gay, Bisexual and Other Men Who Have Sex with Men Living with HIV

Drug Use and HIV Prevention With Young Gay and Bisexual Men: Partnered Status Predicts Intervention Response

Female Gender and HIV Transmission Risk Behaviors Among People Living with HIV Who Have Ever Used Injection Drugs in St. Petersburg, Russia

Influences on Exclusive Breastfeeding Among Rural HIV-Infected South African Women: A Cluster Randomized Control Trial

Associations with Unprotected Sexual Behavior Among HIV-Infected Drinkers in Western Kenya

Identifying Spatial Variation Along the HIV Care Continuum: The Role of Distance to Care on Retention and Viral Suppression

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Chronische Verstopfung: „Versuchen Sie es mit grünen Kiwis!“

Blutdrucksenkung könnte Uterusmyome verhindern

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

Update Innere Medizin