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Critical Care
Erschienen in: Critical Care 5/2009

01.10.2009 | Review

Clinical review: Goal-directed therapy in high risk surgical patients

verfasst von: Nicholas Lees, Mark Hamilton, Andrew Rhodes

Erschienen in: Critical Care | Ausgabe 5/2009

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Abstract

A small group of patients account for the majority of peri-operative morbidity and mortality. These 'high-risk' patients have a poor outcome due to their inability to meet the oxygen transport demands imposed on them by the nature of the surgical response during the peri-operative period. It has been shown that by targeting specific haemodynamic and oxygen transport goals at any point during the peri-operative period, the outcomes of these patients can be improved. This goal directed therapy includes the use of fluid loading and inotropes, in order to optimize the preload, contractility and afterload of the heart whilst maintaining an adequate coronary perfusion pressure. Despite the benefits seen, it remains a challenge to implement this management due to difficulties in identifying these patients, scepticism and lack of critical care resources.
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Metadaten
Titel
Clinical review: Goal-directed therapy in high risk surgical patients
verfasst von
Nicholas Lees
Mark Hamilton
Andrew Rhodes
Publikationsdatum
01.10.2009
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 5/2009
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc8039

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