Background
Methods
Patient and public involvement
Variables of interest
Statistical analysis
Results
ICD code | Number | % | |
---|---|---|---|
All sites | 2315 | ||
Oral cavity & pharynx | C00–14 | 26 | 1.12 |
Digestive system | 1067 | 46.09 | |
Esophagus | C15 | 76 | |
Stomach | C16 | 432 | |
Small intestine | C17 | 9 | |
Colon and rectum | C18, 19, 20 | 385 | |
Anus, anal canal, & anorectum | C21 | 3 | |
Liver & intrahepatic bile duct | C22 | 105 | |
Gallbladder & other biliary | C23, 24 | 46 | |
Pancreas | C25 | 40 | |
Other digestive organs | C26 | 6 | |
Thorax (including heart) | 282 | 12.18 | |
Lung & bronchus | C34 | 228 | |
Other respiratory organs | C30–33, 35–39 | 56 | |
Bones & joints | C40–41 | 3 | 0.13 |
Skin & soft tissue | C43–49 | 50 | 2.16 |
Breast | C50 | 26 | 1.12 |
Genital system | 384 | 16.59 | |
Uterine cervix | C53 | 11 | |
Uterine corpus | C54, 55 | 1 | |
Ovary | C56 | 1 | |
Other genital, female | C51, 52, 57, 58 | 0 | |
Prostate | C61 | 365 | |
Testis | C62 | 4 | |
Other genital, male | C60, 63 | 4 | |
Urinary system | 206 | 8.9 | |
bladder | C67 | 114 | |
Kidney & renal pelvis | C64, 65 | 90 | |
Ureter & other urinary organs | C66, 68 | 16 | |
Eye & orbit | C69 | 1 | 0.04 |
Brain & other nervous system | C70–72 | 4 | 0.17 |
Endocrine system | 58 | 2.51 | |
Thyroid | C73 | 57 | |
Other endocrine | C74, 75 | 1 | |
lymphoid neoplasms | 50 | 2.16 | |
Lymphoma | C81–86, 88 | 28 | |
Myeloma | C90 | 10 | |
Leukemia | C91–95 | 11 | |
Other lymphoid | C96 | 2 | |
Other & unspecified primary sites | C76–80, 97 | 158 | 6.83 |
All patients (n = 11,785) | with cancer (n = 1999) | without cancer (n = 9786) | p-value | |||
---|---|---|---|---|---|---|
Age (year) | ||||||
< 65 | 2755 | 265 | (9.62) | 2490 | (90.38) | <.0001 |
65–69 | 2190 | 374 | (17.08) | 1816 | (82.92) | |
70–74 | 2746 | 531 | (19.34) | 2215 | (80.66) | |
75–79 | 2410 | 513 | (21.29) | 1897 | (78.71) | |
80–84 | 1263 | 243 | (19.24) | 1020 | (80.76) | |
85–89 | 368 | 63 | (17.12) | 305 | (82.88) | |
≥ 90 | 53 | 10 | (18.87) | 43 | (81.13) | |
Sex | ||||||
Male | 9685 | 1798 | (18.56) | 7887 | (81.44) | <.0001 |
Female | 2100 | 201 | (9.57) | 1899 | (90.43) | |
Insurance type | ||||||
Medical aid program | 859 | 137 | (15.95) | 722 | (84.05) | 0.4111 |
National health insurance | 10,926 | 1862 | (17.04) | 9064 | (82.96) | |
Hospital type | ||||||
Tertiary hospital | 8864 | 1501 | (16.93) | 7363 | (83.07) | 0.8855 |
General/small hospital | 2921 | 498 | (17.05) | 2423 | (82.95) | |
Regional area | ||||||
Urban area | 8865 | 1581 | (17.83) | 7284 | (82.17) | <.0001 |
Rural area | 2920 | 418 | (14.32) | 2502 | (85.68) | |
Charlson Comorbidity Index | ||||||
0–1 | 3400 | 520 | (15.29) | 2880 | (84.71) | 0.0003 |
2 | 3252 | 531 | (16.33) | 2721 | (83.67) | |
≥ 3 | 5133 | 948 | (18.47) | 4185 | (81.53) | |
Comorbidities | ||||||
Hypertension | 9791 | 1677 | (17.13) | 8114 | (82.87) | 0.2881 |
DM | 4050 | 809 | (19.98) | 3241 | (80.02) | <.0001 |
Dyslipidemia | 8204 | 1468 | (17.89) | 6736 | (82.11) | <.0001 |
MI | 910 | 171 | (18.79) | 739 | (81.21) | 0.1259 |
ESRD | 160 | 31 | (19.38) | 129 | (80.63) | 0.4129 |
All-cause mortality | with cancer | without cancer | p-value | |||
---|---|---|---|---|---|---|
Patients with intact AAA treated by EVAR or OSR (n = 11,785) | ||||||
30-day mortality | Censored | 1980 | (99.05) | 9676 | (98.88) | 0.4967 |
Event | 19 | (0.95) | 110 | (1.12) | ||
90-day mortality | Censored | 1931 | (96.60) | 9529 | (97.37) | 0.0537 |
Event | 68 | (3.40) | 257 | (2.63) | ||
Total mortality | Censored | 1575 | (78.79) | 8115 | (82.92) | <.0001 |
Event | 424 | (21.21) | 1671 | (17.08) | ||
Patients with intact AAA treated by EVAR (n = 7903) | ||||||
30-day mortality | Censored | 1560 | (99.11) | 6259 | (98.89) | 0.4534 |
Event | 14 | (0.89) | 70 | (1.11) | ||
90-day mortality | Censored | 1521 | (96.63) | 6150 | (97.17) | 0.2570 |
Event | 53 | (3.37) | 179 | (2.83) | ||
Total mortality | Censored | 1242 | (78.91) | 5221 | (82.49) | 0.0010 |
Event | 332 | (22.09) | 1108 | (17.51) | ||
Patients with intact AAA treated by OSR (n = 3882) | ||||||
30-day mortality | Censored | 420 | (98.82) | 3837 | (98.84) | 0.9719 |
Event | 5 | (1.18) | 45 | (1.16) | ||
90-day mortality | Censored | 410 | (96.47) | 3789 | (97.60) | 0.1053 |
Event | 15 | (3.53) | 93 | (2.40) | ||
Total mortality | Censored | 333 | (78.35) | 3227 | (83.13) | 0.0054 |
Event | 92 | (21.65) | 655 | (16.87) |
All-cause mortality | Crude HR (95% CIs) | Adjusted HR (95% CIs)* | ||||
---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Patients with intact AAA treated by EVAR or OSR (n = 11,785) | ||||||
30-day mortality | 0.85 | (0.52–1.38) | 0.83 | (0.50–1.36) | 0.80 | (0.49–1.31) |
90-day mortality | 1.30 | (0.99–1.69) | 1.20 | (0.92–1.58) | 1.16 | (0.89–1.53) |
Total mortality | 1.50 | (1.35–1.67) | 1.31 | (1.18–1.46) | 1.31 | (1.17–1.46) |
Patients with intact AAA treated by EVAR (n = 7903) | ||||||
30-day mortality | 0.80 | (0.45–1.43) | 0.82 | (0.46–1.46) | 0.80 | (0.45–1.43) |
90-day mortality | 1.19 | (0.88–1.62) | 1.17 | (0.86–1.60) | 1.14 | (0.83–1.55) |
Total mortality | 1.40 | (1.24–1.58) | 1.29 | (1.14–1.46) | 1.28 | (1.13–1.46) |
Patients with intact AAA treated by OSR (n = 3882) | ||||||
30-day mortality | 1.02 | (0.40–2.58) | 0.96 | (0.37–2.45) | 0.87 | (0.34–2.24) |
90-day mortality | 1.57 | (0.90–2.73) | 1.35 | (0.77–2.36) | 1.28 | (0.73–2.24) |
Total mortality | 1.55 | (1.24–1.94) | 1.32 | (1.06–1.65) | 1.33 | (1.06–1.66) |
All-cause mortality | Crude HR (95% CIs) | Adjusted HR (95% CIs)* | ||||
---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Patients with intact AAA treated by EVAR or OSR (n = 11,785) | ||||||
30-day mortality | 0.82 | (0.47–1.44) | 0.81 | (0.46–1.41) | 0.79 | (0.45–1.38) |
90-day mortality | 0.98 | (0.70–1.36) | 1.18 | (0.97–1.45) | 0.87 | (0.62–1.21) |
Total mortality | 1.41 | (1.25–1.59) | 1.21 | (1.07–1.36) | 1.21 | (1.07–1.37) |
Patients with intact AAA treated by EVAR (n = 7903) | ||||||
30-day mortality | 0.67 | (0.33–1.33) | 0.68 | (0.34–1.36) | 0.66 | (0.33–1.33) |
90-day mortality | 0.86 | (0.59–1.25) | 0.83 | (0.57–1.22) | 0.80 | (0.55–1.18) |
Total mortality | 1.34 | (1.17–1.53) | 1.21 | (1.05–1.38) | 1.21 | (1.05–1.39) |
Patients with intact AAA treated by OSR (n = 3882) | ||||||
30-day mortality | 1.43 | (0.57–3.63) | 1.38 | (0.70–2.73) | 1.28 | (0.50–3.31) |
90-day mortality | 1.39 | (0.72–2.67) | 1.19 | (0.61–2.31) | 1.14 | (0.59–2.22) |
Total mortality | 1.37 | (1.06–1.78) | 1.13 | (0.87–1.47) | 1.16 | (0.89–1.51) |
All-cause mortality | Crude HR (95% CIs) | Adjusted HR (95% CIs)* | ||||
---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Patients with intact AAA treated by EVAR or OSR (n = 11,785) | ||||||
30-day mortality | 0.84 | (0.44–1.61) | 0.85 | (0.44–1.62) | 0.82 | (0.43–1.57) |
90-day mortality | 1.10 | (0.76–1.58) | 1.04 | (0.72–1.50) | 1.00 | (0.69–1.45) |
Total mortality | 1.45 | (1.26–1.66) | 1.30 | (1.13–1.49) | 1.31 | (1.14–1.50) |
Patients with intact AAA treated by EVAR (n = 7903) | ||||||
30-day mortality | 0.84 | (0.41–1.76) | 0.88 | (0.42–1.82) | 0.87 | (0.21–3.59) |
90-day mortality | 1.06 | (0.71–1.59) | 1.05 | (0.70–1.58) | 1.03 | (0.69–1.54) |
Total mortality | 1.38 | (1.19–1.61) | 1.30 | (1.11–1.51) | 1.31 | (1.12–1.52) |
Patients with intact AAA treated by OSR (n = 3882) | ||||||
30-day mortality | 0.87 | (0.21–3.59) | 0.89 | (0.21–3.68) | 0.55 | (0.13–2.24) |
90-day mortality | 1.06 | (0.43–2.62) | 1.02 | (0.41–2.51) | 1.05 | (0.55–2.00) |
Total mortality | 1.34 | (0.97–1.85) | 1.17 | (0.85–1.62) | 1.21 | (0.87–1.67) |
All-cause mortality | Crude HR (95% CIs) | Adjusted HR (95% CIs)* | ||||
---|---|---|---|---|---|---|
Model 1 | Model 2 | |||||
Patients with intact AAA treated by EVAR or OSR (n = 11,785) | ||||||
30-day mortality | 2.93 | (1.37–6.28) | 2.98 | (1.39–6.41) | 2.97 | (1.38–6.39) |
90-day mortality | 2.33 | (1.37–3.99) | 2.24 | (1.31–3.84) | 2.27 | (1.33–3.89) |
Total mortality | 2.07 | (1.62–2.65) | 1.90 | (1.49–2.43) | 1.95 | (1.52–2.49) |
Patients with intact AAA treated by EVAR (n = 7903) | ||||||
30-day mortality | 2.85 | (1.15–7.03) | 3.05 | (1.23–7.58) | 3.04 | (1.22–7.58) |
90-day mortality | 1.84 | (0.94–3.58) | 1.84 | (0.94–3.58) | 1.90 | (0.97–3.71) |
Total mortality | 1.91 | (1.44–2.54) | 1.77 | (1.33–2.36) | 1.81 | (1.36–2.41) |
Patients with intact AAA treated by OSR (n = 3882) | ||||||
30-day mortality | 3.26 | (0.79–13.47) | 3.08 | (0.74–12.79) | 3.26 | (0.78–13.67) |
90-day mortality | 4.09 | (1.66–10.07) | 3.57 | (1.44–8.83) | 3.69 | (1.48–9.19) |
Total mortality | 2.33 | (1.44–3.77) | 2.25 | (1.39–3.64) | 2.29 | (1.41–3.71) |