P001 Physiological emergence of amyloid-β1-40 with mechanical ventilation-induced cerebral immunochallenge
S Lahiri1, N Sparrow2, L Mangiacotti2, PS Rajput2, M Koronyo2
1Cedars-Sinai Medical Center, Neurocritical Care, Los Angeles, United States; 2Cedars-Sinai Medical Center, Departments of Neurology, Neurosurgery, and Biomedical Sciences, Los Angeles, United States
P002
P003 Molecular mechanisms of xenon neuroprotection (experimental data)
A Kuzovlev1, O Grebenchikov1, A Shabanov2, I Kasatkina1, L Nikolaev3, I Molchanov4
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia; 2Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; N.V. Sklifosofsky Research Institute of Emergency Medicine, Moscow, Russia; 3Russian Academy of Postgraduate Education, Moscow, Russia; 4Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; Russian Academy of Postgraduate Education, Moscow, Russia
P004 Procalcitonin and C-reactive protein are not increased in ventriculostomy-related infections in patients with hemorrhagic stroke
S Wang, E Pietrzko, E Keller, G Brandi
University Hospital Zurich, Neurocritical Care Unit, Dept. of Neurosurgery and Institute of Intensive Care Medicine, Zurich, Switzerland
P005 Central nervous system infections in an intensive care unit: a retrospective study
A Martinho, E Trigo, M Miranda, P Martins
Centro Hospitalar e Universitário de Coimbra - CHUC, Medicina Intensiva, Coimbra, Portugal
P006 Study of selenium levels in unresponsive wakefullness (UWS) patients with systemic inflammatory response syndrome (SIRS)
E Kondratyeva1, S Kondratyev2, N Dryagina2
1Almazov National Medical Reseach Centre, Minimally Conscious Research Group, St Petersburg, Russia; 2Almazov National Medical Reseach Centre, Minimally Conscious Science Group, St Petersburg, Russia
P007 Pharmacokinetics of levetiracetam in critically ill patients with normal and augmented renal clearance
H Barrasa1, I Bilbao-Meseguer2, M Solinís3, A Rodríguez-Gascón3, J Maynar4, E Uson5, G Balziskueta4, F Fonseca4, A Martín4, A Isla6
1University Hospital of Alava, Intensive Care, Vitoria, Spain; 2Cruces University Hospital, Department of Pharmacy, Cruces University Hospital, Barakaldo, Spain; 3Faculty of Pharmacy, PharmaNanoGene Group, Vitoria, Spain; 4University Hospital of Alava, intensive Care, Vitoria, Spain; 5Can Misses Hospital, intensive Care, Ibiza, Spain; 6Faculty of Pharmacy, pharmaNanoGene Group, Vitoria, Spain
P008 Feasibility of quantitative assessment of mechanical properties of muscles in chronic critically ill patients
N Beloborodova, M Petrova, I Buyakova, E Chernevskaya
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
P009 Prognosis of unresponsive wakefulness syndrome outcome based on the determination of certain hormones and natriuretic peptide
E Kondratyeva, N Dryagina, S Kondratyev
Almazov National Medical Reseach Centre, Minimally Conscious Research Group, St Petersburg, Russia
P010 Craniocerebral hypothermia as a neuromodulation method in chronically critically ill patients
M Petrova
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
P011 Transcranial Doppler assessment of cerebral perfusion in pediatric severe sepsis and septic shock
A Mostafa1, A Elbeleidy2, S Awad2, R Hamdi2, H Elgebaly2
1Children Cancer Hospital, Pediatric ICU, Giza, Egypt; 2Cairo University Hospital, Cairo, Egypt
P012 Pupillometry in the follow up of patients undergoing EVT. Could it replace repetitive CT-control
J Koehn, A Giede-Jeppe, M Hagen, JB Kuramatsu, S Schwab, HB Huttner
University of Erlangen-Nuremberg, Department of Neurology, Erlangen, Germany
P013 Automated infrared pupillometry: possible hypotheses of extended application in intensive care unit
F Marturano, F Socci, F Marchi, F Disalvo, G Branchetti, M Bonizzoli, M Ciapetti, A Peris
Careggi Teaching Hospital, Intensive Care Unit and ECMO Referral Center, Florence, Italy
P014 Use of color-coded duplex sonography in neuromonitoring of critical care patients. Experience at Pirovano Hospital in Buenos Aires
DN Gauna, L Macchiavello
Hospital Pirovano, Critical Care, City of Buenos Aires, Argentina
P015
P016
P017 Use of adenosine-induced cardioplegia in anesthesia during endovascular treatment of arteriovenous malformation of the brain
N Lesteva, A. Kondratyev, M Aibazova, D Vasilyev, G Ryibakov, S Lesina
Polenov Neurosurgical Institute - Almazov National Medical Research Centre, Anesthesiology and Intensive Care, Saint-Petersburg, Russia
P018 Incidence of postoperative major adverse cardiac events in patients undergoing carotid endarterectomy: a single-center retrospective study
A Suphathamwit, C Leewatchararoongjaroen
Faculty of Medicine Siriraj Hospital, Mahidol University, Department of Anesthesiology, Bangkok, Thailand
P019 The antithrombotic effects of different oral anticoagulants in the monitoring of acute stroke
M Lawrence1, V Evans2, J Whitley2, S Pillai2, P Slade3, M Krishnan3, K Power4, PA Evans2
1Welsh Center of Emergency Medicine, HBRU, Swansea, United Kingdom; 2Welsh Center of Emergency Medicine, Swansea, United Kingdom; 3Swansea Bay UHB, Stroke Department, Swansea, United Kingdom; 4Swansea Bay UHB, Pharmarcy, Swansea, United Kingdom
P020 HAIR-score optimalisation in subarachnoidal bleeding
L Capiau1, H Vanoverschelde1, A Decruyenaere2, J Decruyenaere1, K Colpaert1
1Ghent University Hospital, Intensive Care Unit, Ghent, Belgium; 2Ghent University Hospital, Internal Medicine, Ghent, Belgium
P021 South American experience with urapidil in neurocritical care patients
M Canitrot1, J Ramirez2, J Serra3, L Brunetto3, Y Santos3, R Villa4, I Previgliano4, S Ugarte3
1INDISA Clinic, Critical Care, Santiago, Chile; 2Andres Bello University, NeuroICU, Santiago, Chile; 3INDISA Clinic, NeuroICU, Santiago, Chile; 4Hospital General J. A. Fernandez, NeuroICU, Buenos Aires, Argentina
P022 Poor-grade aneurysm subarachnoid hemorrhage in neuro ICU: how poor is their prognosis?
M Canitrot1, J Ramirez2, J Serra3, Y Santos3, V Munoz3, JL Sufan3, J Contreras3, F Paravic4, C Droguett4, S Ugarte2
1INDISA Clinic, Critical Care, Santiago, Chile; 2Andres Bello University, NeuroICU, Santiago, Chile; 3INDISA Clinic, NeuroICU, Santiago, Chile; 4INDISA Clinic, Neurorehabilitation, Santiago, Chile
P023 Success in intravenous thrombolysis with alteplase for acute ischemic stroke: a matter of distance?
P Papamichalis1, AL Skoura1, P Katsiafylloudis1, E Neou1, S Karagiannis1, E Dardiotis2, M Karvouniaris1, D Papadopoulos1, T Zafeiridis1, A Komnos1
1General Hospital of Larissa, Department of Intensive Care, Larissa, Greece; 2University Hospital of Larissa, Department of Neurology, Larissa, Greece
Distance | p Value | |
---|---|---|
Thrombolysis time | (Spearman´s rho: 0.41) | < 0.001a b |
Thrombolysis time: 3 hours (n= 121) / 3-4.5 (n=36) | 16400 (400 - 72600) / 37500 (1400 – 88600) | < 0.001c b |
Complications: NO (n= 148) / YES (n= 9) | 20300 (400 - 88600) / 37000 (2700 - 72600) | 0.04c b |
Death (3 months): NO (n= 136) / YES (n= 21) | 20200 (400 - 88600) / 27700 (450 - 72600) | 0.24 c d |
Functional outcome: mRS≤2 (n= 103) / mRS>2 (n= 54) | 18800 (400 - 88600) / 25900 (450 - 77100) | 0.03c b |
P024 Influence of pneumonia on delayed cerebral infarction after subarachnoid hemorrhage: a retrospective study
T Gargadennec1, V Vermeersch1, J Ognard2, M Geslain1, P Ariès1, J Le Roy1, H Floch1, A De Tinténiac3, X Chapalain1, O Huet1
1Brest University Hospital, Département d´Anesthésie et Réanimation Chirurgicale, Brest, France; 2Brest University Hospital, Service de Radiologie et Imagerie Médicale, Brest, France; 3Brest University Hospital, Brest, France
P025 Association of prehospital hypocarbia and hypercarbia with outcomes with severe traumatic brain injury patients
Z Weisner1, D Salcido1, F Guyette1, H Siddiqui1, J Salerno1, J Elmer2
1UPMC Presbyterian, Emergency Medicine, Pittsburgh, United States; 2UPMC Presbyterian, Emergency Medicine and Critical Care, Pittsburgh, United States
P026 Psychiatric drug burden after intensive care unit treated pediatric traumatic brain injury
E Mikkonen1, M Skrifvars2, R Raj 2
1Helsinki University Hospital & University of Helsinki, Department of Anesthesiology, Intensive Care and Pain Medicine and Department of Emergency Care and Services, Helsinki, Finland; 2Helsinki University Hospital & University of Helsinki, Helsinki, Finland
GOS, 5-11 years | Any prescription | Antidepressant | Stimulant | Antipsychotic |
3, n= 5 | 2 (40%) | 0 (0%) | 1 (20%) | 1 (20%) |
4, n= 10 | 3 (30%) | 1 (10%) | 3 (30%) | 0 (0%) |
5, n= 63 | 3 (5%) | 1 (2%) | 1 (2%) | 1 (2%) |
GOS, 12-17 years | ||||
3, n= 16 | 5 (31%) | 4 (25%) | 0 (0%) | 2 (13%) |
4, n= 42 | 19 (45%) | 15 (36%) | 1 (2%) | 10 (24%) |
5, n= 107 | 14 (13%) | 12 (11%) | 3 (3%) | 3 (3%) |
P027 The effects of 1-adamantylethyloxy-3-morpholino-2-propanol hydrochloride on the formation of steroid neurotoxicity in rats with brain injury
A. Semenenko1, S. Semenenko2, A. Solomonchuk3, N. Semenenko3
1National Pirogov Memorial Medical University, Department of Anesthesiology, Intensive Care and Emergency Medicine, Vinnytsya, Ukraine; 2National Pirogov Memorial Medical University, Departament of Clinical Pharmacy and Clinical Pharmacology, Vinnytsya, Ukraine; 3National Pirogov Memorial Medical University, Vinnytsya, Ukraine
P028 YKL-40 and neuron-specific enolase as prognostic biomarkers in traumatic brain injury
G Pavlov1, M Kazakova2, V Dichev2, D Vasilev3, K Simitchiev4, C Stefanov3, V Sarafian2
1Medical University of Plovdiv, Department of Anesthesiology, Emergency and Intensive Care Medicine *University Hospital “St. George” Plovdiv, Bulgaria, Plovdiv, Bulgaria; 2Medical University of Plovdiv, Department of Medical Biology, Medical Faculty, Medical University- Plovdiv, Bulgaria, Plovdiv, Bulgaria; 3Medical University of Plovdiv, Department of Anesthesiology, Emergency and Intensive Care Medicine, Medical Faculty, Medical University- Plovdiv, Bulgaria, Plovdiv, Bulgaria; 4University of Plovdiv, Department of Analytical Chemistry and Computer Chemistry, Faculty of Chemistry, University of Plovdiv, Bulgaria, Plovdiv, Bulgaria
P029 Cerebro-vascular perfusion correlation index (CPC) predicts outcomes in severe traumatic brain injury
D Colombo1, G Berdin2, A Scerrati3, G Golino4, E Bonaldi2, E Roman-Pognuz5, P Persona6, MA Martin2, S De Rosa7
1SS. Trinità Hospital,Borgomanero, Borgomanero, Novara, Italy; 2San Bortolo Hospital, Department of Anesthesia and Intensive Care Medicine, Vicenza, Italy; 3San Bortolo Hospital, Department of Neurosurgery, Vicenza, Italy; 4San Bortolo Hospital, Department of Medicine – DIMED, Section of Anesthesiology and Intensive Care Medicine, Vicenza, Italy; 5Azienda Sanitaria Universitaria Integrata di Trieste, Hospital of Trieste, Department of Anesthesia and Intensive Care Medicine, Trieste, Italy; 6University of Padova, Department of Medicine – DIMED, Section of Anesthesiology and Intensive Care Medicine, Padova, Italy; 7San Bortolo Hospital, Department of Intensive Care, Vicenza, Italy
Variable | Odds ratio | 95%CI | P |
---|---|---|---|
CPC | 0.0029 | 0.0000 to 0.8336 | 0.0431 |
ICP | 1.0614 | 0.9300 to 1.2115 | 0.3768 |
CPP | 1.0128 | 0.8519 to 1.2041 | 0.8854 |
PaCO2 | 1.1137 | 0.8738 to 1.4195 | 0.3843 |
Glucose | 1.0322 | 0.9905 to 1.0757 | 0.1319 |
Lactate | 0.2381 | 0.0237 to 2.3900 | 0.2227 |
Internal body temperature | 7.2637 | 0.4385 to 120.3210 | 0.1662 |
P030 The brain heart interaction - dynamic relationship between variability of heart rate, interventions and outcome in traumatic brain injury
BA Ianosi1, V Rass1, A Lindner1, P Smielewski2, A Ercole3, R Beer1, A Schiefecker1, B Pfausler1, N Stocchetti4, R Helbok1
1Medical University of Innsbruck, Neurological Intensive Care Unit, Department of Neurology, Innsbruck, Austria; 2Cambridge University, Division of Neurosurgery, Cambridge, United Kingdom; 3Cambridge University, Division of Anaesthesia, Cambridge, United Kingdom; 4Ospedale Maggiore Policlinico, Department of Anesthesia and Critical Care, Milano, Italy
P031 Temperature and cerebral autoregulation in severe TBI patients
BA Ianosi1, V Rass1, A Lindner1, M Kofler1, A Schiefecker1, R Beer1, B Pfausler1, N Stocchetti2, A Ercole3, R Helbok1
1Medical University of Innsbruck, Neurological Intensive Care Unit, Department of Neurology, Innsbruck, Austria; 2Ospedale Maggiore Policlinico, Department of Anesthesia and Critical Care, Milano, Italy; 3Cambridge University, Division of Anaesthesia, Cambridge, United Kingdom
P032 Brain temperature after traumatic injury: a center-TBI study
T Birg1, F Ortolano1, M Carbonara1, T Zoerle1, R Helbok2, Y Savchenko3, BA Ianosi2, N Stocchetti1
1Fondazione IRCCSC a’Granda Ospedale Maggiore Policlinico, Neurointensive care unit, Milan, Italy; 2University of Innsbruck, Department of Neurology, Innsbruck, Austria; 3Burdenko Neurosurgical Center, Neurointensive care unit, Moscow, Russia
P033 Subclinical AKI in severe traumatic brain injury
S De Rosa1, G Golino2, G Villa3, S Samoni4, M De Cal4, MA Martin5, G Berdin5, P Persona2, P Navalesi2, C Ronco6
1San Bortolo Hospital, Department of Intensive Care, Vicenza, Italy; 2University of Padova, Department of Medicine – DIMED, Section of Anesthesiology and Intensive Care Medicine, Padova, Italy; 3University of Florence, Department of Anesthesia and Intensive Care Medicine, Florence, Italy; 4San Bortolo Hospital, Department of Nephrology, Vicenza, Italy; 5San Bortolo Hospital, Department of Anesthesia and Intensive Care Medicine, Vicenza, Italy; 6San Bortolo Hospital, Department of Medicine, University of Padova, Padova-Italy, Vicenza, Italy
P034 Benchmarking outcomes after severe traumatic brain injury with the CRASH and IMPACT prediction models: a single center analysis in the Netherlands
WR Van de Peppel1, HF Lingsma2, I Haitsma3, M Van der Jagt4
1Erasmus MC - University Medical Center, Departments of Intensive Care Adults, Rotterdam, Netherlands; 2Erasmus MC - University Medical Center, Department of Public Health, Rotterdam, Netherlands; 3Erasmus MC - University Medical Center, Department of neurosurgery, Rotterdam, Netherlands; 4Erasmus MC - University Medical Center, Department of Intensive Care Adults, Rotterdam, Netherlands
P035 Neuroprognostication following out of hospital cardiac arrest
R Davidson1, T Bagnall2, M Ahmed3
1St George´s Hospital Cardiothoracic Intensive Care, Atkinson Morley Wing, London, United Kingdom; 2Kingston Hospital, Cardiology, London, United Kingdom; 3St George´s Hospital Cardiothoracic Intensive Care, London, United Kingdom
Presenting rhythm | Total patients | Survival to discharge |
---|---|---|
VF/VT | 62 | 65% |
PEA/asystole | 33 | 24% |
P036
P037 Audit of end of life care and neuroprognostication in the intensive care department at Bristol Royal Infirmary
KJ Richardson, M Thomas
Bristol Royal Infirmary, Intensive Care Unit, Bristol, United Kingdom
P038 Target temperature management after out of hospital cardiac arrest
P Liddicoat, M Ahmed, A Obhrai
St George's Hospital, Intensive Care, Tooting, United Kingdom
P039 Serum GFAP and UCH-L1 for the prediction of long term neurological outcome in comatose out-of-hospital cardiac arrest patients
F Ebner1, M Moseby-Knappe2, N Mattsson2, J Undén3, S Ullén4, T Cronberg2, N Nielsen5
1Helsingborg Hospital, Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Helsingborg, Sweden; 2Skane University Hospital, Lund University, Skane University Hospital, Department of Clinical Sciences Lund, Neurology, Lund, Sweden; 3Halland Hospital, Lund University, Halland Hospital, Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Halmstad, Sweden; 4Skane University Hospital, Clinical Studies Sweden, Skane University Hospital, Lund, Sweden; 5Helsingborg Hospital, Lund University, Helsingborg Hospital, Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Helsingborg, Sweden
P040 Blood pressure after cardiac arrest and severity of hypoxic-ischemic encephalopathy
C Endisch1, S Preuß2, C Storm3, CJ Ploner1, C Leithner1
1Charité Universitätsmedizin Berlin, Department of Neurology, AG Emergency and Critical Care Neurology, Berlin, Germany; 2Charité Universitätsmedizin Berlin, Departement of Cardiology, Berlin, Germany; 3Charité Universitätsmedizin Berlin, Department of Nephrology and Internal Intensive Care Medicine, Berlin, Germany
P041
P042
P043 P25/30 somatosensory evoked potentials and neurological outcome in comatose survivors of out of hospital cardiac arrest
N Nikitas1, L Nye2, C Bigham1, N Broomfield2, A MacCormick1, L Lankester1, N Gourd1, R Squire3, E Dunn2, N Hudson2
1University Hospitals Plymouth NHS Trust, Department of Intensive Care Medicine, Plymouth, United Kingdom, 2University Hospitals Plymouth NHS Trust, Department of Neurophysiology, Plymouth, United Kingdom, 3University Hospitals Plymouth NHS Trust, Department of Emergency Medicine, Plymouth, United Kingdom
P044 Relationship between shockable rhythm and long-term outcome in pediatric out-of-hospital cardiac arrest in Rotterdam, the Netherlands: a 16 year observational study.
M Albrecht1, RCJ De Jonge1, M Hunfeld1, JAE Kammeraad1, XRJ Moors1, VM Nadkarni2, L van Zellem1, CMP Buysse1
1Erasmus MC – Sophia Children's Hospital, Intensive Care and Department of Pediatric Surgery, Rotterdam, the Netherlands; 2Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA., USA
P045 Acute kidney injury in cardiac arrest patients
S Bazzano1, G Villa2, G Golino3, S Samoni4, M De Cal4, S Marcante5, M Martin5, R Vaschetto1, C Ronco4, S De Rosa6
1Università degli studi del PIemonte Orientale, Department of Anesthesia and Intensive Care Medicine, Novara, Italy; 2University of Florence, Department of Anesthesia and Intensive Care Medicine, Florence, Italy; 3University of Padova, Department of Medicine – DIMED, Section of Anesthesiology and Intensive Care Medicine, Padova, Italy; 4San Bortolo Hospital, Department of Nephrology, Vicenza, Italy; 5San Bortolo Hospital, Department of Anesthesia and Intensive Care Medicine, Vicenza, Italy; 6San Bortolo Hospital, Department of Intensive Care, Vicenza, Italy
P046 Socioeconomic status is associated with early coronary angiography after out-of-hospital cardiac arrest
R Lagedal1, M Jonsson2, L Elfwén3, D Smekal4, P Nordberg2, S James5, S Rubertsson4
1Department of Surgical Sciences, Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden; 2Department of Surgical Sciences, Anaesthesia and Intensive Care, Department of Medicine, Center for Resuscitation Science, Karolinska Institute, Solna, Sweden; 3Department of Surgical Sciences, Anaesthesia and Intensive Care, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institute, Sweden, Uppsala, Sweden; 4Department of Surgical Sciences, Anaesthesia and Intensive Care, Department of Surgical Sciences/Anesthesiology and Intensive Care Medicine, Uppsala University, Uppsala, Sweden; 5Department of Surgical Sciences, Anaesthesia and Intensive Care, Department of Medical Sciences, Cardiology, and Uppsala Clinical Research Center Uppsala University, Uppsala, Sweden
P047 Effect of simulation teaching of cardiopulmonary resuscitation for nursing
V Spatenkova1, I Danilova2, Z Jindrisek2, M Fronkova2, I Veverkova2
1Faculty of Health Studies, Technical Faculty of Liberec, Neurocenter, NICU, Liberec, Czech Republic; 2Faculty of Health Studies, Technical Faculty of Liberec, Liberec, Czech Republic
P048
P049 Changes in blood gases during intraoperative cardiac arrest
JJ Wang, R Borgstedt, S Rehberg, G Jansen
Protestant Hospital of the Bethel Foundation, Anaesthesiology, Intensive Care and Emergency medicine, Transfusion medicine and Pain therapy, Bielefeld, Germany
Blood gases | Before CA (n[%]) | During CA (n[%]) | During CA ROSC (n[%]) | During CA (n[%]) |
---|---|---|---|---|
pH <7.35 | 18 [62] | 29 [78] | 19 [73] | 10 [91] |
pH >7.45 | 4 [14] | 2 [5] | 1 [4] | 1 [1] |
PaCO2 <35mmHg | 9 [31] | 7 [19] | 6 [23] | 1 [1] |
PaCO2 >45mmHg | 6 [21] | 21 [57] | 15 [58] | 6 [55] |
PaO2 <100mmHg | 5 [17] | 12 [32] | 9 [34] | 3 [27] |
PaO2 100-200mmHg | 28 [28] | 8 [22] | 6 [23] | 2 [18] |
PaO2 >200mmHg | 16 [55] | 17 [46] | 11 [42] | 6 [55] |
P050 Diagnostic strategies in intensive care unit cardiac arrest
FO Holland1, S Entz2, S Lamprinaki2, M Abu-Tair1, R Borgstedt3, S Rehberg3, G Jansen3
1Protestant Hospital of the Bethel Foundation, Department of Internal Medicine, Cardiology, Nephrology and Diabetology, Bielefeld, Germany; 2Protestant Hospital of the Bethel Foundation, Department of Internal Medicine and Gastroenterology, Bielefeld, Germany; 3Protestant Hospital of the Bethel Foundation, Department of Anaesthesiology, Intensive Care, Emergency Medicine, Transfusion Medicine, and Pain Therapy, Bielefeld, Germany
Overall | No-ROSC | ROSC | p-value | |
---|---|---|---|---|
ICU-CA | 114 | 37 | 77 | - |
Age [years] | 72 ± 12 | 74 ± 9 | 72 ± 13 | 0.2 |
Male [n(%)] | 78 (68) | 25 (68) | 53 (69) | 0.89 |
Diagnostic done [n(%)] | 50 (44) | 25 (68) | 25 (32) | 0.0004 |
Therapeutic consequence [n(%)] | 27 (54) | 8 (32) | 19 (76) | 0.001 |
P051 Continuous monitoring of cardiac patients on general ward were improved short term survival of in-hospital cardiac arrest
UJ Go1, YJ Shin1, JM Lee1, HY Oh1, SB Hong2
1Medical Alert Team, Asan Medical Center, Seoul, South Korea; 2Asan Medical Center, Department of Pulmonary and Critical care medicine, Seoul, South Korea
Survival | Illness category | Monitored n(%) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) |
---|---|---|---|---|
ROSC | Cardiac | 73 (83.0) | 2.79 (1.37-5.68) | 2.86 (1.02-8.08) |
ROSC | Noncardiac | 329 (72.0) | 1.24 (0.92-1.67) | 0.68 (0.44-1.05) |
72-hour survival | Cardiac | 59 (67.0) | 2.08 (1.13-3.85) | 2.40 (1.04-5.51) |
72-hour survival | Noncardiac | 215 (47.0) | 1.13 (0.86-1.49) | 0.80 (0.52-1.23) |
Survival to hospital discharge | Cardiac | 35 (39.8) | 1.50 (0.80-2.81) | 1.36 (0.58-3.20) |
Survival to hospital discharge | Noncardiac | 109 (23.9) | 0.95 (0.69-1.30) | 0.69 (0.45-1.06) |
P052 Physiologic effects of steroids in in-hospital cardiac arrest (CORTICA study group1,2)
E Pappa1, E Ischaki1, S Malachias1, A Giannopoulos1, K Vrettou1, G Karlis1, I Pantazopoulos1, D Makris2, S Zakynthinos1, S Mentzelopoulos1
1Evaggelismos General Hospital, First Department of Intensive Care Medicine University of Athens Medical School, Athens, Greece; 2Larisa University Hospital, Department of Intensive Care Medicine, University of Thessaly Medical School, Larissa, Greece
P053 The experiences of EMS providers taking part in a large randomized trial of airway management during out of hospital cardiac arrest, and the impact on their views and practice. Results of a survey and telephone interviews
M Thomas1, M Robinson2, K Kirby3, J Brandling3, S Voss3, J Benger3
1Bristol Royal Infirmary, Intensive Care Unit, Bristol, United Kingdom; 2South West Ambulance Service, Exeter, United Kingdom; 3University of West of England, Bristol, United Kingdom
P054 Causes of medical care-associated cardiac arrest on the intensive care unit
S Entz1, FO Holland2, S Lamprinaki1, M Abu Tair2, M Krüger1, R Borgstedt3, S Rehberg3, G Jansen3
1Protestant Hospital of the Bethel Foundation (EvKB), Department of Internal Medicine and Gastroenterology, Bielefeld, Germany; 2Protestant Hospital of the Bethel Foundation (EvKB), Department of Internal Medicine, Cardiology and Nephrology, Bielefeld, Germany; 3Protestant Hospital of the Bethel Foundation (EvKB), Department of Anaesthesiology, Intensive Care, Emergency Medicine, Transfusion Medicine and PainTherapy, Bielefeld, Germany
Total [n(%)] | ROSC [n(%)] | no ROSC [n(%)] | No vasopressors before ICUCA [n(%)] | |
---|---|---|---|---|
induction of anaesthesia | 11(39) | 8(73) | 3(27) | 8(72) |
bedding procedures | 7(25) | 4(57) | 3(43) | 3(43) |
other medication | 4(14) | 3(75) | 1(25) | 1(25) |
injuries (pneumo-/hematothorax, tracheotomy injury) | 3(11) | 2(67) | 1(3) | 3(100) |
switching syringes for continuous infusions | 2(7) | 2(100) | 0(0) | 0(0) |
no pacemaker in AV-block III | 1(4) | 0(0) | 1(100) | 1(100) |
28(100) | 19(68) | 9(32) | 16(57) |
P055
P056 Favorable effects of reducing low-flow duration in ECPR patients
A Higashi1, TA Nakada1, T Imaeda1, R Abe1, K Shinozaki2, S Oda1
1Chiba University Graduate School of Medicine, Department of Emergency and Critical Care Medicine, Chuo, Chiba, Japan; 2The Feinstein Institute for Medical Research, The Feinstein Institute for Medical Research, Manhasset, United States
P057 Clinical features and outcomes of in-hospital cardiac arrest in Code Blue events: a retrospective observational study
M Akatsuka, H Tatsumi, H Kuroda, S Kazuma, W Aisaka, S Suzuki, K Kikuchi, Y Goto, M Kodama, Y Masuda
Sapporo Medical University School of Medicine, Department of Intensive Care Medicine, Sapporo, Japan
P058 Peri-operative cardiac arrest in prematurity – incidence and causes at a tertiary care hospital between 2008-2018
G Jansen, J Popp, E Lang, R Borgstedt, B Schmidt, S Rehberg
Protestand Hospital of the Bethel Foundation, Anaesthesiology, Intensive Care and Emergency Medicine, Bielefeld, Germany
Peri-operative Phase | n | Cause | n |
---|---|---|---|
Induction | 1 | Difficult airway | 1 |
Maintenance | 8 | Hemorrhagic shock | 4 |
Mucus obstructed endotracheal tube | 2 | ||
Dislocated endotracheal tube | 1 | ||
Septic Shock | 1 | ||
Awakening | 1 | Hypoxaemic attack in case of fallot-pentalogy | 1 |
P059 Peri-operative pediatric cardiac arrest – incidence and mortality in 22,650 pediatric anesthetics at a tertiary care hospital between 2008-2018
G Jansen1, J Popp2, E Lang1, R Borgstedt1, B Schmidt1, S Rehberg1
1Protestand Hospital of the Bethel Foundation, Anaesthesiology, Intensive Care and Emergency Medicine, Bielefeld, Germany; 2Protestand Hospital of the Bethel Foundation, Bielefeld, Germany
Age | n | Anesthesias | Incidence (per 10.000) | Mortality (per 10.000) |
---|---|---|---|---|
< 28 days | 10 | 642 | 155.8 | 62.3 |
28 days-<1 year | 5 | 2922 | 17.1 | 6.8 |
1- ≤5 years | 2 | 8096 | 2.5 | 1.3 |
6- ≤12 years | 1 | 7882 | 1.3 | 1.2 |
13-≤15 years | ´0 | 3108 | - | - |
P060 In-hospital cardiac arrest - predicting adverse outcomes
T Partington, J Borkowski, J Gross
Northwick Park Hospital, Anaesthesia/Critical Care, London, United Kingdom
- Comorbidities and functional status
- Admission details
- Post-arrest events
P061 Investigation of factors determining mortality in out-of-hospital cardiac arrest (OCHA)
C Balci1, O Kucuk2, E Haftaci3, E Karaca4, S Ozbay4, H Karaca4
1Kutahya Healty Science Un, Anaesthesiology and Reanimation, Kutahya, Turkey; 2Balıkesir City Hospital, ICU, Balıkesir, Turkey; 3Karaman Goverment Hospital, Karaman, Turkey; 4Derince Traning Hospital, Anaesthesiology and Reanimation, Kocaeli, Turkey
P062 Time factors, basic life support performance and outcomes of out-of-hospital cardiac arrests detected by schoolchildren
H Inaba1, K Takada2, H Kurosaki2, Y Wato3, A Yamashita2
1 Kanazawa University Graduate School of Medicine, Department of Circulatory Emergency and Emergency Medical Science, Kanazawa, Japan; 2Kanazawa University Graduate School of Medicine, Kanazawa, Japan; 3Kanazawa Medical University, Uchinada, Japan
P063 Prognostic value of neutrophil/lymphocyte and platelet/lymphocyte predicting cardiopulmonary resuscitation with spontaneous circulation recovery
C Li
the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China
P064 Neurofilament light chain as an outcome predictor after cardiac arrest
L Wihersaari1, N Ashton2, M Reinikainen1, P Jakkula3, V Pettilä3, J Hästbacka3, M Tiainen3, K Blennow2, H Zetterberg2, MB Skrifvars3
1University of Eastern Finland and Kuopio University Hospital, Department of Anaesthesiology and Intensive Care, Kuopio, Finland; 2University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden; 3University of Helsinki and Helsinki University Hospital, Helsinki, Finland
P065 Changes in iron metabolism and prognosis of patients with out-of-hospital cardiac arrest
P Aries1, O Huet1, O Tocquer1, M Consigny2, T Lefebvre3, M Padelli4, E Lher5, JM Tonnelier5, C Aubron5
1Brest Teaching Hospital, Departement of Anaesthesia and Surgical Intensive Care, Brest, France; 2Brest Teaching Hospital, Centre d’Investigation Clinique CIC INSERM 1412, CHRU Brest, Brest, France; 3Hôpital Louis Mourier HUPNVS, Biochimie/Centre Français des Porphyries, Colombes, France; 4Brest Teaching Hospital, Département de Biochimie et Pharmaco-toxicologie, Brest, France, 5Brest Teaching Hospital, Department of Medical Intensive Care Unit, Brest, France
P066 Association between early hyperoxia after out of hospital cardiac arrest with return of spontaneous circulation and 30-day survival
A Awad1, J Olsson2, P Nordberg1, M Jonsson3, M Ringh1, J Hollenberg3, E Joelsson-Alm2
1Karolinska Institute, Solna, Sweden, Department of Medicine, Center for Resuscitation Science, Solna, Stockholm, Sweden; 2Karolinska Institute, Solna, Sweden, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden, Solna, Stockholm, Sweden; 3Karolinska Institute, Solna, Sweden, Solna, Stockholm, Sweden
P067 Correlation between increased inflammation and early-onset pneumonia in patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation
D Shiba1, T Hifumi2, N Otani2, S Ishimatsu2
1St. Luke´s International Hospital, Emergency Department, Tokyo, Japan; 2St. Luke´s International Hospital, Tokyo, Japan
P068 Mode of death after cannulation for venoarterial extracorporeal membrane oxygenation, insights from a single center registry
V Zotzmann1, J Rilinger2, CN Lang2, M Jäckel2, T Wengenmayer2, C Bode 2, D Staudacher3
1University of Freiburg, Heart Center, Freiburg, Germany; 2University of Freiburg, Freiburg, Germany; 3University of Freiburg, University of Freiburg, Freiburg, Germany
P069 ECMO mobile team for donor cardiac death. a pilot ECMO-TT study
R Badenes1, C Álvarez2, F Hornero3, J Guijarro3, JM Segura3, R Zaragoza2
1Hospital Clinic Universitari de Valencia, Department of Anesthesiology and Surgical-Trauma Intensive Care, Valencia, Spain; 2Hospital Dr. Peset, Valencia, Spain; 3Hospital Clinic Universitari de Valencia, Valencia, Spain
P070 Veno-venous extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant
C Palfreeman, P Vila, J Sokhi, A Hurtado-Doce
Harefield Hospital, Critical Care, Harefield, United Kingdom
P071 What is the useful coagulation and fibrinolysis marker for predicting extracorporeal membrane oxygenation circuit exchange due to intra-circuit thrombus?
Y Izutani, K Hoshino, S Morimoto, K Muranishi, J Maruyama, Y Irie, Y Kawano, H Ishikura
Fukuoka University Hospital, Emergency and Critical Care Center, Fukuoka-shi, Japan
P072 Inhomogeneity of lung elastance in patients who underwent veno-venous extra corporeal membrane oxygenation (V-V ECMO)- a computed tomography scan study
RD Di Mussi1, RI Iannuzziello2, FM Murgolo2, FD De Carlo2, E Caricola2, NA Barrett3, LC Camporota3, SG Grasso2
1Università degli studi di Bari "Aldo Moro", Department of emergencies and organ transplant, Bari, Italy; 2Università degli studi di Bari "Aldo Moro", Bari, Italy; 3Department of Adult Critical Care, Guy´s and St Thomas´ NHS Foundation Trust, King´s Health Partners, London, UK
P073 Phase 3, pilot, prospective, randomized, single blinded, multicenter, controlled, two-arm trial on antithrombin supplementation during extracorporeal membrane oxygenation. the GATRA (Grifols Antithrombin Research Awards) study
M Panigada1, A Cucino1, E Cipriani1, S De Falco1, E Spinelli1, G Occhipinti2, G Panarello2, A Arcadipane2, A Pesenti1, G Grasselli1
1Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico, Intensive Care Unit, Milano, Italy; 2Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT), Intensive Care Unit, Palermo, Italy
P074 Prone positioning while extracorporeal membrane oxygenation therapy in severe ARDS
J Rilinger, V Zotzmann, X Bemtgen, PM Biever, D Duerschmied, C Bode, DL Staudacher, T Wengenmayer
Heart Center Freiburg University, Department of Cardiology and Angiology I, Freiburg, Germany
P075 Cause-specific mortality during extracorporeal membrane oxygenation, a single center review of medical records
M Panigada, D Tubiolo, P Properzi, G Grasselli, A Pesenti
Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico, Intensive Care Unit, Milano, Italy
P076 Non-invasive mechanical ventilation in veno-venous extracorporeal membrane oxygenation
J Rilinger, V Zotzmann, X Bemtgen, PM Biever, D Duerschmied, C Bode, DL Staudacher, T Wengenmayer
Heart Center Freiburg University, Department of Cardiology and Angiology I, Freiburg, Germany
P077 Intra-hospital transportation on extracorporeal membrane oxygenation (ECMO) - a single centre experience in Ireland.
Z Siddique, S O´Brien, E Carton, I Conrick-Martin
Mater Misericordiae University Hospital, Department of Critical Care Medicine, Dublin, Ireland
Total number of transfers | 28 |
Most common indication for transfer | CT brain |
Sites of cannulation | Peripheral > central |
Staff members involved in transport | 4 to 10 |
Time of transportation | 35 to 195 minutes |
Complications arising during transport | 12 |
P078 A novel approach for flow simulation in ECMO rotary blood pumps
A Supady1, C Benk2, J Cornelis3, C Bode1, D Duerschmied1
1Heart Center Freiburg University, Cardiology and Angiogiology I, Freiburg, Germany; 2Heart Center Freiburg University, Department of Cardiovascular Surgery, Freiburg, Germany; 3FIFTY2 Technology GmbH, 79108 Freiburg, Germany
P079 One-year experience of bedside percutaneous VA-ECMO decannulation in a territory ECMO center in Hong Kong
KM Fong, SY Au, PW Leung, KC Shek, HJ Yuen, SK Yung, HL Wu, SO So, WY Ng, KH Leung
Queen Elizabeth Hospital, Intensive Care Unit, Hong Kong
P080 CD52 positive NKT cells predict survival during veno-arterial extracorporeal membrane oxygenation
EJ Kort1, MW Weiland1, EG Eugster1, EG Grins2, SF Fitch3, GM Marco4, T Timek4, ML Leacche4, TJ Boeve4, SJ Jovinge5
1Van Andel Institute/Spectrumhealth, Grand Rapids, United States; 2Scania Univ Hosp Lund/Lund Univ, Dep of Clinical Medicine, Scania Univ Hosp Lund/Lund Univ Lund Sweden, Lund, Sweden; 3DeVos CV Res/Fredrik Meijer Heart and Vascular Inst Spectrumhealth, Spectrumhealth, Grand Rapids, MI United States, Grand Rapids, MI, United States; 4DeVos CV Res/Fredrik Meijer Heart and Vascular Inst Spectrumhealth, Grand Rapids, MI, United States; 5Van Andel Institute/Spectrumhealth, DeVos Cardiovascular Research Program, Grand Rapids, United States
P081 Neurologic complications in adult postcardiotomy cardiogenic shock patients receiving venoarterial extracorporeal membrane oxygenation: a cohort study
H Wang, D Hou
Beijing Anzhen Hospital, Capital Medical University, Center for Cardiac Intensive Care, Beijing, China
P082 Use of levosimendan during weaning of mechanical circulatory support
S Hendrickx, J Verbeke, N De Neve, K De Decker
OLV Aalst, Intensive Care, Aalst, Belgium
Discharge Home | Deceased | Total | ||
---|---|---|---|---|
On ECLS or within 24h | After weaning | |||
All | 7 (31,8%) | 5 (22.7%) | 10 (45.4%) | 22 |
Male | 7 (41.2%) | 4 (23.5%) | 5 (29.4%) | 17 |
Female | 0 (0%) | 1 (20%) | 4 (80%) | 5 |
<60y | 5 (45,5%) | 2 (18.2%) | 4 (36.4%) | 11 |
>60y | 3 (27.2%) | 3 (27.2%) | 5 (45.5%) | 11 |
P083 A series of two hemorrhage-associated pheochromocytoma crises precipitating cardiogenic shock requiring extracorporeal life support.
P O´Connor, C Costello, S Egan, M Afrasenei, S O´Brien, E Carton, I Conrick-Martin
Mater Misericordiae University Hospital, Critical Care Medicine, Dublin 1, Ireland
P084 Cardiac tamponade complicating extracorporeal membrane oxygenation: a single center experience
A Fontoura1, R Roncon-Albuquerque Jr.2, JA Paiva2, C Basílio2
1Unidade Local de Saúde da Guarda, Intensive Care Medicine Department, Guarda, Portugal; 2Centro Hospitalar Universitário de São João, Intensive Care Medicine Department, Porto, Portugal
P085 Extracorporeal CO2 removal reduces inspiratory muscle effort during renal replacement therapy in a difficult to wean patient after orthotopic liver transplantation: a case report
I Cavalli
Alma Mater Studiorum - Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche Anesthesia and Intensive Care Medicine, Policlinico di Sant´Orsola, Bologna, Italy, Bologna, Italy
P086 AKI during aeCOPD: the potential role of combined renal-respiratory extracorporeal support
L Zamidei1, R Marco2, D Atzeni3, G Boscolo4, F Turani5, G Consales1
1Prato Hospital, emergency and Intensive Care, Prato, Italy; 2IRCCS Policlinico San Donato, Anesthesia and Intensive Care Department, San Donato, Italy; 3Marino Hospital, Intensive Care Department, Cagliari, Italy; 4Ospedale dell´Angelo, Anaesthesia and Intensive Care Department, Mestre, Italy, 5Aurelia and European Hospital, Anesthesia and Intensive Care Department, Rome, Italy
P087 Extracorporeal carbon dioxide removal rates during the SUPERNOVA trial: estimates from a mathematical model
JK Leypoldt1, J Kurz2, J Goldstein3, D Pouchoulin4, JG Laffey5, K Harenski2
1Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Modeling and Supporting of Internal Functions, Warsaw, Poland; 2Baxter Deutschland GmbH, Medical Affairs, Unterscheissheim, Germany; 3Baxter World Trade SPRL, Acute Therapies Global, Braine-l´Alleud, Belgium; 4Baxter, Gambro Industries, Research and Development, Meyzieu, France; 5School of Medicine, NUI Galway, Anesthesia and Intensive Care Medicine, Galway, Ireland
Hemolung | Hemolung | iLA/Cardiohelp | iLA/Cardiohelp | |
---|---|---|---|---|
Time After TV = 4.1 mL/kg PBW | 8 hours | 24 hours | 8 hours | 24 hours |
ECCO2R Rate (mL/min) | 44 | 71 | 131 | 141 |
P088 Efficiency and safety of a system CRRT plus ECCO2R to allow ultra-protective ventilation protocol in patients with acute renal failure
F Maldarelli1, FA Alessandri1, RD D´Albo1, FP Pugliese1, MV Ranieri2
1Sapienza University of Rome, Department of Anesthesia and Critical Care Medicine, Policlinico Umberto I, Rome, Italy; 2Alma Mater Studiorum Università di Bologna, Policlinico Sant´Orsola, Scienze mediche e chirurgiche, Bologna, Italy
P089
P090 Calculating the optimal ventilator strategy to reduce mechanical power in patients with extracorporeal carbon dioxide removal (ECCO2R)
KF Bachmann, M Haenggi, D Berger
Inselspital Bern, University Hospital, Bern, Switzerland, Department of Intensive Care Medicine, Bern, Switzerland
P091 Validity of empirical estimates of physiological dead space in acute respiratory distress syndrome
JD Dianti, EG Goligher, AS Slutsky
University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Canada
Measured | Estimated | R2 | Bias and limits of agreement | |
---|---|---|---|---|
VD/VT | 0.56 (±0.11) | 0.61 (±0.14) | 0.21 | Bias= 0.05 (LOA= 0.21 – 0.31) |
VDalv/VT | 0.14 (±0.08) | 0.3 (±0.12) | 0.11 | Bias= 0.17 ( LOA= -0.07 – 0.41) |
Anatomical dead space fraction (VDanat/VT) | 0.45 (±0.11) | 0.34 (±0.06) | 0.12 | Bias= -0.11 (LOA= -0.33 – 0.11) |
VCO2 | 208 (±66) | 178 (±49) | 0.39 | Bias= -29.7 (LOA= -132 – 73) |
P092 Efficacy of PEEP on cyclic recruitment/derecruitment (R/D) in ARDS patients with different percentage of potentially recruitable lung
Y Tang, Q Sun, S Liu, X Liu, J Zhang, S Fan, C Pan, L Liu, H Qiu
Southeast University, School of Medicine, Zhongda hospital, Department of Critical Care Medicine, Nanjing, China
P093 Early neuromuscular blockers in acute respiratory distress syndrome: a systematic review and meta-analysis
PY Gonzalez noris1, I Rivera2
1ISSSTE General Hospital, Intensive Care Unit, La Paz, Mexico; 2ISSSTE General Hospital, Anesthesiology, La Paz, Mexico
P094
P095 The role of ultrasound in the detection of pulmonary infiltrates in critically ill patients with hematologic malignancies and acute respiratory failure
MM Grgic Medic, NG Gubarev Vrdoljak, OZ Zlopasa, RR Radonic
University Hospital Centre Zagreb, Internal Medicine, Zagreb, Croatia
P096 Right ventricular dysfunction is associated with mortality in patients with pneumonia admitted to intensive care
M Chotalia1, M Bangash1, T Matthews1, M Kalla2, D Parekh1, J Patel1
1University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom
P097 Validation of a new method for estimation of the change in pleural pressure using the change in central venous pressure in various clinical scenarios: a pig model study
M Kyogoku1, S Mizuguchi2, T Miyasho3, Y Endo4, Y Inata1, K Tachibana5, K Yamashita6, M Takeuchi1
1Osaka Women´s and Children´s Hospital, Intensive Care, Osaka, Japan; 2Kyushu University, Emergency and Critical Care Center, Fukuoka, Japan; 3Rakuno Gakuen University, Laboratory of Animal Biological Responses Department of Veterinary Science School of Veterinary Medicine, Hokkaido, Japan; 4Sapporo Night Animal Hospital, Hokkaido, Japan; 5Osaka Women´s and Children´s Hospital, Anesthesiology, Osaka, Japan; 6Rakuno Gakuen University, Anesthesiology, Hokkaido, Japan
P098 The role of ultrasound in monitoring diaphragm activity in critically ill patients
F Righetti1, E Colombaroli2
1Intensive Care Unit, Fracastoro Hospital, Emergency Department, San Bonifacio, Verona, Italy; 2Intensive Care Unit, Fracastoro Hospital, San Bonifacio, Verona, Italy
P099 Does high flow nasal oxygen therapy reduce extubation failure in critically ill patients?
A Mcguire, R Sundaram
Intensive Care Unit, Royal Alexandra Hospital, Royal Alexandra Hospital, Paisley, United Kingdom
Number | Percentage | |
---|---|---|
Ventilated >48 hours | 1076 | 76.2% |
Extubated | 718 | 66.7% |
Reintubated within 24 hours | 126 | 17.6% |
Reintubated overall | 184 | 25.6% |
Reintubated HFNO used | 100 | 54.3% |
Remained extubated | 534 | 74.4% |
Remained extubated HFNO used | 221 | 41.4% |
P100 Introduction new practice of endotracheal tube holder to intubated patient to improve oral care in intensive care unit
YT Ho1, WT Yeung2, OK Lee2, PO Lei2, MT Lai2, SC Ho2, EH Chan2, LY Law2, KY Ho2, HC Yuen2
1Ruttonjee & Tang Shiu Kee Hospitals, Cardiac & Intensive Care Unit, Hong Kong; 2Ruttonjee & Tang Shiu Kee Hospitals, Hong Kong
P101 Execution of percutaneous dilatational tracheostomy using the standard laryngeal mask airway for ventilation: a prospective survey study
G Gagliardi1, V Gagliardi2, C Chiani3, G Laccania4, F Michielan3
1AULSS 5 - Veneto, Anesthesia and Intensive Care, Adria, Italy; 2AULSS 5 - Veneto, University of Padua, Adria, Italy; 3AULSS 5 - Veneto, Anaesthesia and Intensive Care, Adria, Italy; 4AULSS 6 - Veneto, Anaesthesia and Intensive Care, Padua, Italy
P102 Dilatative percutaneous tracheostomy vs surgical tracheostomy: what late complications?
F Righetti1, E Colombaroli2
1Intensive Care Unit, Fracastoro Hospital, Emergency Department, San Bonifacio, Verona, Italy; 2Intensive Care Unit, Fracastoro Hospital, San Bonifacio, Verona, Italy
P103 Is there benefit to delaying tracheostomy?
FS Zimmerman, PD Levin
Shaare Zedek Medical Center, Intensive Care Unit, Jerusalem, Israel
Variable | extubated n=62 (%) | tracheostomy n=131 (%) | p-value | |
---|---|---|---|---|
Demographics | Male | 45 (72.6) | 78 (59.5) | 0.108 |
Age - years ± CI | 63±8 | 63±6 | 0.915 | |
Surgical patient | 28 (45.2) | 50 (38.2) | 0.432 | |
APACHE II score ± CI | 22±1 | 21±1 | 0.425 | |
Outcomes | In-hospital mortality | 9 (14.5) | 37 (28.2) | 0.046 |
ICU LOS, h, median (IQR) | 422 (288-518) | 383 (204-601) | 0.152 | |
hospital LOS, h, median (IQR) | 857 (628-1180) | 1236 (857-1633) | 0.001 |
P104
P105 Retrospective audit of tracheostomy insertion in a training intensive care unit in Singapore
D Bruce-Hickman1, G Aquino Vergel De Dios2, P A Dela Cruz2, F Khan3
1Ng Teng Fong General Hospital, Singapore; 2Ng Teng Fong General Hospital, Respiratory Therapy, Singapore; 3Ng Teng Fong General Hospital, Intensive Care Medicine, Singapore
P106 Impact of bronchoscopically graded inhalation injury on outcomes in critically ill burns patients: 12-year experience at a regional burns centre
WN Charles1, K Matwala1, A Dutt1, S Mandalia2, D Collins3, S Singh4
1Imperial College London, Department of Surgery and Cancer, London, United Kingdom; 2Chelsea and Westminster Hospital NHS Foundation Trust, Department of Research and Development, London, United Kingdom; 3Chelsea and Westminster Hospital NHS Foundation Trust, Department of Plastic and Reconstructive Surgery, London, United Kingdom; 4Chelsea and Westminster Hospital NHS Foundation Trust and Royal Brompton and Harefield NHS Foundation Trust, Magill Department of Anaesthesia, Intensive Care and Pain Management, London, United Kingdom
P107 A quality improvement project to prevent hyperoxia in a developing world intensive care unit
J Harrington, D Hall, TY Wang, M Murali, S Mwansa
University Teaching Hospital, Anaesthesia, Lusaka, Zambia
P108 Epidemiology and factors associated with tracheal intubation in pediatric burned population
S Lebrun, N Akrout, N Louvet, I Constant
Hopital Armand Trousseau (APHP), Anesthesie-Réanimation, Paris, France
P109 An analysis of the predictive applicability of initial blood gas parameters for the need for intubation and the presence of inhalation injury in patients with suspected inhalation injury
C Pirrone1, M Chotalia2, T Mangham1, R Mullhi1, K England1, T Torlinski1
1University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom
Need for intubation for more than 48 hours | Presence of inhalation injury | |
---|---|---|
pH | 0.203 | 0.241 |
PaCO2 | 0.715 | 0.691 |
PaO2 | 0.458 | 0.408 |
PF ratio | 0.437 | 0.467 |
COHb | 0.536 | 0.604 |
P110 Lung protection during lung cancer surgery by non-intubated spontaneous breathing - a case series
P Friederich1, F Fuchsgruber2, A Hiebinger3, H Angerer2, J Bodner3
1München Klinik Bogenhausen, Technische Universität München, Anesthesiology, Critical Care, München, Germany; 2München Klinik Bogenhausen, Technische Universität München, Anaesthesiology, Critical Care, München, Germany; 3München Klinik Bogenhausen, Technische Universität München, Thoracic Surgery, München, Germany
P111 The effect of early cuff deflation on weaning in tracheostomized patients requiring ventilatory support on the intensive care unit
C Carroll1, L Poole2, C Lamont2, I Welters2
1University of Liverpool, Liverpool, United Kingdom; 2Liverpool University Hospitals NHS Foundation Trust, Intensive Care Unit, Liverpool, United Kingdom
P112 Preventing underinflation of the endotracheal tube cuff with a portable elastomeric device. A randomized controlled study
JE Dauvergne1, AL Geffray2, K Asehnoune2, B Rozec1, K Lakhal1
1Hopital Laënnec - CHU de Nantes, Service d´anesthésie-réanimation, Nantes, France; 2Hotel-Dieu - CHU de Nantes, Service d´anesthésie-réanimation, Nantes, France
P113 Percutaneous tracheotomy in ICU advantage and complications
V Pajtic1, S Zjalic2, B Josipovic2, N Ilic2, B Radanovic2, D Barac2, L Gvozdenovic3, S Lovrencic2
1University of Novi Sad, Faculty of Medicine, Clinic for Anesthesia Intensive and Pain Therapy Clinical Center of Vojvodina, Novi Sad, Serbia; 2Clinic for Anesthesia Intensive and Pain Therapy Clinical Center of Vojvodina, Novi Sad, Serbia; 3University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia
P114 A comparison of the intersurgical i-View and Macintosh laryngoscope when used by novice personnel: a manikin study
MO O´Sullivan1, EO Imhoff-O´Mahony2
1Mercy University Hospital, Anaesthesiology and Intensive Care, Cork, Ireland; 2Sligo University Hospital, Anaesthesiology and Intensive Care, Sligo, Ireland
P115 Assessing predictors of success in airway pressure release ventilation (APRV)
SF Villegas1, M McHendry1, S Gillon2, M Al-Haddad1
1Queen Elizabeth University Hospital, Department of Critical Care, Glasgow, United Kingdom; 2Royal Infirmary of Edinburgh, Department of Critical Care, Edinburgh, United Kingdom
Variable | Responder (n=48) | Non-responder (n=48) | P value |
---|---|---|---|
APACHE II score | 21.5 (8.4) | 23.6 (10.5) | 0.311 |
Fluid balance (ml) | +3258 (4107) | +4172 (5508) | 0.382 |
Hours ventilated prior to APRV | 53.3 (65) | 87 (213) | 0.3 |
PaCO2 | 6.7 (1.8) | 7.6 (2.5) | 0.047 |
PEEP | 11.0 (3.2) | 10.0 (3.1) | 0.12 |
PF Ratio | 13.9 (6.8) | 16.7 | 0.189 |
Primary pulmonary pathology | 70.8% | 50% | 0.037 |
P116 Preventing atelectasis during closed endotracheal suctioning
C Lima1, G Alcala1, S Gomes1, R Santiago2, M Amato1
1University of Sao Paulo Medical School, Pulmonary Division, Heart Institute (InCor), São Paulo, Brazil; 2Massachusetts General Hospital, Department of Anesthesia, Critical Care and Pain Medicine, Boston, United States
P117 Tyrosine kinase inhibitor: an effective tool against lung cancer involvement responsible for acute respiratory failure in ICU
Y Tandjaoui-lambiotte1, Y Akrour1, F Gonzalez2, A Stoclin3, F El Kouari4, A Gibelin5, F Wallet6, A Oppenheimer7, B Duchemann8, S Gaudry1
1Avicenne Hospital, Intensive Care Unit, Bobigny, France; 2Institut Paoli Calmettes, Intensive Care Unit, Marseille, France; 3Institut Gustave Roussy, Intensive Care Unit, Villejuif, France; 4Pitié Salpetrière Hospital, Pharmacy, Paris, France; 5Tenon Hospital, Intensive Care Unit, Paris, France; 6Lyon Sud Hospital, Intensive Care Unit, Lyon, France; 7Versailles-Saint-Quentin University (UVSQ), EA 7285 Research Unit ´Risk and Safety in Clinical Medicine for Women and Perinatal Health´, Montigny-le-Bretonneux, France; 8Avicenne Hospital, Oncology, Bobigny, France
P118 Community-acquired pneumonia: factors predicting poor outcome
C Bozikovich1, A Ramos2, A Dogliotti3, B Espinosa1, N Rodriguez1, C Lovesio2
1Sanatorio Parque, Internal Medicine, Rosario, Argentina; 2Sanatorio Parque, Critical Care, Rosario, Argentina; 3Grupo Oroño, Epidemiology and statistics, Rosario, Argentina
P119 Mortality study of burn patients with inhalation injury in a critical burn unit
L Cachafeiro1, A Agrifoglio1, M Sánchez1, E Herrero1, A García de Lorenzo2
1Hospital Universitario La Paz, Intensive Care Medicine Service, Madrid, Spain; 2Hospital Universitario La Paz, Madrid, Spain
P120 Consistency of aerosol dosing during the progression of respiratory therapy in the hospital setting
E Fernandez fernandez1, G Bennett1, A Tatham1, A O´ Sullivan2, P McKiernan1, M Mac Giolla Eain2, M Joyce2, R MacLoughlin2
1Aerogen, Medical Affairs, Galway, Ireland; 2Aerogen, Science, Galway, Ireland
P121 The underlying inflammatory effect of stable COPD (chronic obstructive pulmonary disease) patient on thrombogenicity and clot microstructure
S Pillai1, M Lawrence2, J Whitley3, K Harrison3, E Evans4, A Mughal4, S Hilldrup4, PR Williams5, K Morris6, PA Evans3
1Welsh Centre for Emergency Medicine Research, Emergency Department, Morriston Hospital, Swansea, United Kingdom; 2Welsh Centre for Emergency Medicine Research, Emergency Department, Morriston Hospital, Swansea, United Kingdom; 3Welsh Centre for Emergency Medicine Research, Emergency Department, Morriston Hospital, Swansea, United Kingdom; 4Respiratory Medicine, Morriston Hospital, Swansea, United Kingdom; 5Swansea University, Swansea, United Kingdom; 6Cardiff Metropolitan University, Cardiff, United Kingdom
P122 Respiratory support for lung cancer patients with acute respiratory failure
HK Atalan1, ME Kavlak1, B Gucyetmez2, ZT Sarikaya2
1Memorial Atasehir Hospital, Intensive Care Unit, Istanbul, Turkey; 2Mehmet Ali Aydinlar Acibadem University, Intensive Care Unit, İstanbul, Turkey
P123 Association between PEEP level and renal blood flow in mechanically ventilated patients
A Fogagnolo1, C Calandra2, M Dres3, E Morelli2, G Benetto2, F Franchi4, S Scolletta5, CA Volta2, S Spadaro2
1Morphology, Surgery and Experimental Medicine, University Anaesthesia and Intensive Care, Ferrara, Italy; 2Morphology, Surgery and Experimental Medicine, Ferrara, Italy; 3Sorbonne Universités, Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France; 4University Hospital of Siena, Department of Medicine, Surgery and Neurosciences, Anesthesia and Intensive Care Unit, Siena, Italy; 5University Hospital of Siena, Siena, Italy
P124 Alveolar and respiratory mechanics modifications produced by different concentrations of oxygen in healthy rats subjected to mechanical ventilation with protective ventilatory strategy
D Dominguez Garcia1, R Hernandez Bisshopp1, JL Martin Barrasa2, D Viera Camacho1, A Rodriguez Gil1, J Arias Marzan1, S Garcia Hernandez3, L Perez Mendez4, F Valladares Parrilla3, J Villar2
1Hospital Universitario Ntra. Sra. de Candelaria, Anesthesiology and Surgical Critical Care, Santa Cruz de Tenerife, Spain; 2Hospital Universitario de Gran Canaria Dr. Negrín, Research Unit, Las Palmas de Gran Canaria, Spain; 3University of La Laguna, Anatomy, Pathology and Histology, La Laguna, Spain; 4Hospital Universitario Ntra. Sra. de Candelaria, Research Unit, Santa Cruz de Tenerife, Spain
P125 Clinical outcomes among patients requiring prolonged acute vs. short-term mechanical ventilation in the US, 2014-2018: results from a multicenter cohort study
M Zilberberg1, B Nathanson2, J Ways3, A Shorr4
1EviMed Research Group, LLC, Goshen, United States; 2OptiStatim, LLC, Longmeadow, United States; 3Lungpacer Medical Inc., Exton, United States; 4Washington Hospital Center, Washington, United States
P126 Use of spontaneous breathing trials and extubation data in Scottish ICUs - 2018 Scottish Intensive Care Society trainee audit
A Short1, K Puxty2, D Hall3, J Gardner1, S Chapman4, N Lone3, N Stewart5
1QEUH, Intensive Care Unit, Glasgow, United Kingdom; 2Glasgow Royal Infirmary, Intensive Care Unit, Glasgow, United Kingdom; 3Edinburgh Royal Infirmary, Intensive Care Unit, Edinburgh, United Kingdom; 4Ninewell Hospital, Intensive Care Unit, Dundee, United Kingdom, 5Forth Valley Royal Hospital, Intensive Care Unit, Larbert, United Kingdom
Total population (n=172) | Successful first extubation attempt (n=145) | Failed first extubation attempt (n=27) | Univariate analysis (p-value) | |
Time from intubation to first extubation <3days – | 115 (66.9) | 92 (63.4) | 23 (85.2) | 0.02 |
SBT not performed – no. (%) | 69 (40.1) | 53 (36.6) | 16 (59.3) | 0.03 |
Total SBT population (n=103) | Successful first extubation (n=92) | Failed first extubation (n=11) | ||
T-piece - no. (%) | 9 (8.7) | 8 (8.7) | 1 (9.1) | - |
CPAP only - no. (%) | 64 (62.1) | 58 (63.0) | 6 (54.6) | - |
PS 5-8 ≥ PEEP - no. (%) | 28 (27.2) | 24 (26.1) | 4 (36.4) | - |
P127 Both right and left ventricular dysfunction are associated with an increased mortality in patients undergoing prolonged invasive ventilation
M Chotalia1, M Bangash2, T Matthews2, M Kalla2, D Parekh2, J Patel2
1University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom
P128 Temporary transvenous diaphragm neurostimulation improves volume distribution during mechanical ventilation
E Rohrs, M Ornowska, T Bassi, K Fernandez, M Nicholas, S Reynolds
Simon Fraser University, BPK, Burnaby, Canada
P129 Assessment of the relation Pswing/tidal volume during spontaneous ventilation test, as a predictor of successful weaning
F Galiotti1, G Pagella2, M Carmona1, R Paffumi1, D Minzer1, G Zakalik1, P Riera1, A Chena1
1Hospital Luis Carlos Lagomaggiore, UCI, mendoza, Argentina; 2Hospital Luis Carlos Lagomaggiore, Terapia intensiva, Mendoza, Argentina
DVT | DPS | DVT/DPS * 100 | |
---|---|---|---|
SUCCESS | 4.56 | 0.24 | 18.75 |
FAILURE | 112.3 | 2.45 | 45.8 |
P value | 0.036 | 0.063 | 0.082 / Or = 1.2 |
P130 Predicting weaning failure in CABG patients: role of echocardiographic evaluation of LVOT-VTI
E Favilli1, G Brizzi2, P Bertini2, C Vullo2, R Baldassarri2, L Doroni2, D Amitrano2, F Guarracino2
1Scuola di specializzazione in Malattie dell´Apparato Cardiovascolare, Università di Pisa, Pisa, Italy; 2Department of Cardiothoracic Anesthesia and Intensive Care Medicine, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
P131 Compliance with guidelines for respiratory therapy in preclinical emergency medicine
G Jansen, N Kappelhoff, S Rehberg
Protestand Hospital of the Bethel Foundation, Anaesthesiology, Intensive Care and Emergency Medicine, Bielefeld, Germany
Trainee | Consultants | |
---|---|---|
Compliant with guidelines [n(%)] | Compliant with guidelines [n(%)] | |
RR | 39(97) | 116(97) |
Vt | 35(87) | 103(86) |
Pmax | 37(92) | 117(98) |
PEEP | 24(60) | 56(47) |
P132 Analysis of inflammatory hippocampal cells after 50 hours of lung-protective mechanical ventilation in a preclinical pig model
T Bassi, E Rohrs, K Fernandez, M Ornoswka, M Nicholas, S Reynolds
Simon Fraser University, Physiology, Burnaby, Canada
P133 Predicting weaning from mechanical ventilation after lung transplantation
L Chiscano1, M García-de-Acilu1,2, J Sacanell1, C Laborda1, L Sánchez3, M Ribas4, C Berastegui5, R Ferrer1,6, O Roca1,6
1Vall d’Hebron University Hospital, Critical Care Department, Vall d’Hebron Research Institute, Barcelona, Spain; 2Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain; 3Vall d’Hebron University Hospital, Department of Respiratory Medicine, Vall d’Hebron Research Institute, Barcelona, Spain; 4Vall d’Hebron University Hospital, Department of Thoracic Surgery, Vall d’Hebron Research Institute, Barcelona, Spain; 5Vall d’Hebron University Hospital, Department of Anesthesiology, Vall d’Hebron Research Institute, Barcelona, Spain; 6Ciber Enfermedades Respiratorias (CibeRes), Instituto de Salud Carlos III, Madrid, Spain
Extubation success (N=63) | Extubation failure (N=6) | P-value | ||
---|---|---|---|---|
Pre-SBT | RR | 17 (15 - 20) | 16 (15 - 16) | 0.27 |
PaO2/FIO2 | 235 (218-278) | 218 (218-220) | 0.06 | |
PaCO2 (mmHg) | 40 (38 - 41) | 38 (37 - 39) | 0.56 | |
20 min T-piece | RR | 18 (15 - 23) | 23 (16 - 23) | 0.43 |
PaO2/FIO2 | 233 (219-265) | 188 (188-188) | <0.001 | |
PaCO2 (mmHg) | 40 (38 - 43) | 42 (40 - 43) | 0.33 | |
DE<10mm | 10 (15.87%) | 3 (50%) | 0.08 | |
DTF<0.3 | 48 (76.2%) | 5 (83.3%) | 1 |
P134 Descriptive study about the relationship between self-extubation episodes and patient-ventilator interaction
S Nogales1, C De Haro 1, M Batlle2, L Sarlabous3, J Aquino Esperanza3, G Gomà1, J López Aguilar3, L Blanch3
1Parc Tauli Hospital Universitari, Intensive care unit, Sabadell, Spain; 2Fundació Althaia. Xarxa Assistencial Universitària de Manresa., Intensive care unit, Manresa, Spain; 3Institut d´investigació i Innovació I3PT, Institut d´investigació i Innovació, Sabadell, Spain
P135 Postoperative complications and mortality after transcatheter aortic valve implantation: a retrospective, single Belgian center analysis
E Buts1, P Vermeersch2, S Verheye2, C Convens2, B Scott2, P Dewulf1, P Rogiers1
1ZNA Middelheim, Intensive Care, Antwerp, Belgium; 2ZNA Middelheim, Cardiology, Antwerp, Belgium
P136 Deterioration of pulmonary hypertension after TAVI predicts mid- to long-term poor prognosis
H Yamamoto1, S Kayama1, Y Watanabe2, M Sugi3, T Ikeda4, S Sawamura1
1Teikyo University Hospital, Anesthesia, Tokyo, Japan; 2Teikyo University Hospital, Cardiology, Tokyo, Japan; 3Tokyo Medical University Hachioji Medical Center, Anesthesia, Tokyo, Japan, 4Tokyo Medical University Hachioji Medical Center, Specific intensive care, Tokyo, Japan
P137 The anti-thrombotic effects of different P2Y12 inhibitors in the management of acute ST elevation myocardial infarction
R Quarry1, M Lawrence2, A Sabra2, D Obaid2, A Chase3, D Smith3, J Whitley2, S Pillai3, K Morris4, PA Evans2
1Morriston Hospital, Emergency Department, Swansea, United Kingdom; 2Swansea University, Welsh Centre for Emergency Medicine Research, Swansea, United Kingdom; 3Morriston Hospital, Welsh Centre for Emergency Medicine Research, Swansea, United Kingdom; 4Cardiff Metropolitan University, Welsh Centre for Emergency Medicine Research, Cardiff, United Kingdom
P138 Management of new onset atrial fibrillation in a district general hospital intensive care unit
A Munro, M Yousif, W Du, R Sarkar, N Divekar
Medway Maritime Hospital, Intensive Care Unit, Gillingham, United Kingdom
P139 Assessing the role of cardiac biomarkers in the emergency department in a Moroccan hospital
S Abouradi1, R Benmalek1, R Habbal1, M Mouhaoui2
1Cardiology Department, CHU Ibn Rochd, Casablanca, Cardiology, Casablanca, Morocco; 2Emergency Department, CHU Ibn Rochd, Emergency Department, Casablanca, Morocco
P140 A multicenter study on the comparison of inter-rater reliability of a new and the original HEART score among emergency physicians from three Italian emergency departments
N Parenti1, ML Bacchi Reggiani2, F Numeroso3, L Bonfanti3, G Farina4, V Pezzilli5, C Campanella6, G Cervellin3, M Cavazza5, V Stanghellini5
1Largo Nigrisoli, Internal Medicine, Bologna, Italy; 2University of Bologna Alma Mater, Biostatistics, Bologna, Italy; 3University Hospital of Parma, Emergency Dept, Parma, Italy; 4University of Bologna Alma Mater, Emergency Dept, Bologna, Italy; 5University of Bologna Alma Mater, Internal Medicine, Bologna, Italy; 6Nova Southeastern University USA, Internal Medicine, Davie, Florida, United States
P141 A hybrid approach as treatment for coronary artery disease: endo-CABG or PCI first, does it matter?
V Dekoninck1, A Yilmaz2, J Dubois3, JP Ory3, J Vandenbrande3, B Stessel3
1Jessa, Intensive Care & Anesthesiology, Hasselt, Belgium; 2Jessa, Cardiothoracic Surgery, Hasselt, Belgium; 3Jessa, Anesthesiology & Intensive Care, Hasselt, Belgium
P142 Prognostic difference between troponin elevation meeting the MI criteria and troponin elevation due to myocardial injury in septic patients
A Shilova1, D Shchekochikhin2, M Gilyarov3, A Nesterov4, A Svet5
1Moscow City Univercity hospital #1 n.a. Pirogov, ICCU, Moscow, Russia; 2Moscow City Univercity hospital #1 n.a. Pirogov, Cardiology, Moscow, Russia; 3Moscow City Univercity hospital #1 n.a. Pirogov, Cardiology, Moscow, Russia; 4Moscow City Univercity hospital #1 n.a. Pirogov, Cardiology, Moscow, Russia; 5Moscow City Univercity hospital #1 n.a. Pirogov, Management, Moscow, Russia
P143 Diagnostic interest of "Marburg Heart Score" in patient consulting the emergencies department for acute chest pain
NE Nouira1, M Lehyeni1, A Lahouegue1, K Hamzaoui1, D Hamdi1, M Boussen2
1Mongi Slim Academic Hospital, Emergency Department, Tunis, Tunisia; 2Mongi Slim Academic Hospital, Tunis, Tunisia
P144 Fluid management in abdominal aortic aneurysm surgery in elderly patients
D Lončar Stojiljković1, MP Stojiljkovic2
1Institut Dedinje, Anesthesia and Intensive Care, Belgrade, Serbia; 2Institut Dedinje, Belgrade, Serbia
P145 Should preoperative antihypertensive agents be hold in high risk hypertensive patients undergoing major noncardiac surgery with neuraxial block?
S Kongsayreepong1, W Chaisi2
1Siriraj Hospital, Anesthesiology & Critical Care, Bangkok, Thailand; 2Siriraj Hospital, Bangkok, Thailand
P146 Clinical importance of ultrasonographic assessment of skeletal muscle mass in patients after cardiothoracic surgery
V Raidou1, S Dimopoulos2, F Chatzivasiloglou1, D Elaiopoulos2, A Robola2, D Markantonaki2, E Lyberopoulou2, A Marathias2, S Nanas1, A Karabinis2
1National and Kapodestrian University of Athens, Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, Athens, Greece; 2Onassis Cardiac Surgery Center, Cardiac Surgery ICU, Athens, Greece
P147 Prediction of cardiac risk after major abdominal surgery
S Musaeva, I Tarovatov, A Vorona, I Zabolotskikh, N Doinov
Kuban State Medical University, Anesthesiology and Intensive Care, Krasnodar, Russia
P148 Cognitive dysfunction in rats after minor and major surgery
V Sharipova, A Valihanov, A Alimov
Republican Research Centre of Emergency Medicine, Anesthesiology, Tashkent, Uzbekistan
Minor surgery (n=20) | Major surgery (n=20) | p | |
---|---|---|---|
Surgery duration, min | 22.6 ± 6.3 | 20.1 ± 3.7 | 0.134 |
Anesthesia duration, min | 41.2 ± 8.5 | 36.3 ± 8.2 | 0.071 |
TTQ-1, sec | 59.5 ± 12.1 | 51.2 ± 13.7 | 0.049 |
TTQ-2, sec | 57.8 ± 9.7 | 52.4 ± 12.5 | 0.135 |
TAC-1 | 4.9 ± 2.7 | 3.3 ± 1.9 | 0.036 |
TAC-2 | 4.6 ± 2.1 | 3.4 ± 2.3 | 0.093 |
P149 Cardiac inflammatory markers in ICU patients with myocardiac ischemia after non cardiac surgery (a pilot study)
P Manthou1, G Lioliousis2, P Vasileiou3, G Fildissis1
1National Kapodistrian University of Athens, Athens, Greece; 2National Kapodistrian University of Athens, General Thoracic Hospital ´´Sotiria´´, Athens, Greece; 3National Kapodistrian University of Athens, University of Athens, Athens, Greece
P150 Airway complications after thyroid surgery
V Artemenko1, A Budnyuk2
1MC MEDICAP, Anesthesia&ICU, Odessa, Ukraine; 2Odessa Regional Hospital, ICU, Odessa, Ukraine
Laryngeal edema | Pearson´s criteria | Recurrent nerve injury | Pearson´s criteria | |
---|---|---|---|---|
Euthyroid goiter (170 pts) | 4 | 0.116 weak | 2 | 0.082 NaN |
Polynodos goiter (125 pts) | 7 | 0.194 weak | 4 | 0.147 weak |
Thyroid gland cancer (105 pts) | 11 | 0.271 moderate | 6 | 0.203 weak |
P151 Serum iron level and development of multiple organ dysfunction syndrome in patients in the perioperative period
S Tachyla
Mogilev Regional Hospital, Department of Anesthesiology and Intensive Care, Mogilev, Belarus
P152 Infection in simultaneous pancreas-kidney transplantation
T Isidoro Duarte1, J Marques2, J Silva3, J Estevão1, N Germano1
1Curry Cabral Hospital, Central Lisbon University Hospital Center, Intensive Care Medicine Department, Lisboa, Portugal; 2Curry Cabral Hospital, Central Lisbon University Hospital Center, Nephrology Department, Lisboa, Portugal; 3Covilhã Hospital, Cova da Beira Hospital Center, Internal Medicine Department, Covilhã, Portugal
P153 Thrombotic complications predictors in children underwent cardiac surgery with CPB
V Lastovka1, O Gordeeva2, A Bidzhiev2
1National Medical Research Center for Children´s Health, pediatric ICU, Moscow, Russia; 2National Medical Research Center for Children´s Health, Moscow, Russia
P154 C-reactive protein level variation as a predictor of ischemic complications after vascular surgery
SM Fernandes1, D Conduto2, C Candeias1, JM Ribeiro3
1Centro Hospitalar Universitário Lisboa Norte, Serviço de Medicina Intensiva, Lisboa, Portugal; 2Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal, 3Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal
P155 Postoperative C-reactive protein concentrations to predict infective complications following gastrectomy for cancer
M Van Winsen1, ST McSorley2, R McLeod1, A MacDonald3, M Forshaw3, K Puxty1
1Dept of Anaesthetics and Critical Care, Glasgow Royal Infirmary and University of Glasgow, Glasgow, United Kingdom; 2Academic Unit of Surgery, University of Glasgow, Glasgow, United Kingdom; 3Dept of Upper GI Surgery, Glasgow Royal Infirmary, Glasgow, United Kingdom
P156 Renin in cardiopulmonary bypass-associated vasoplegic syndrome
MM Juarez1, SJ Pearson1, BM Morrissey1, NW Flemming2, P Devarajan3, LS Chawla4, TE Albertson1
1University of California, Davis School of Medicine, Department of Internal Medicine, Pulmonary and Critical Care and Sleep Medicine, Sacramento, United States; 2University of California, Davis School of Medicine, Department of Anesthesiology and Pain Medicine, Sacramento, United States; 3Cincinnati Children´s Hospital Medical Center, University of Cincinnati College of Medicine, Division of Nephrology and Hypertension, Cincinnati, United States; 4Veterans Affairs Medical Center, San Diego, USA and La Jolla Pharmaceutical Company, San Diego, United States
P157 Blood loss and transfusion in minimal invasive coronary artery bypass surgery
K Buyck1, J Vandenbrande1, JP Ory1, J Dubois1, A Yilmaz2, B Stessel1
1Jessa Hospital, Critical Care, Hasselt, Belgium; 2Jessa Hospital, Cardiac Surgery, Hasselt, Belgium
Total transfusion (blood) (units) | Total blood loss (ml) | ||
---|---|---|---|
Total group (n=423) | 0.7 ± 3.07 0 (0, 0) | 428.2 ± 343.3 314.5 (247.8, 499.3) | |
Use of pre-operative medication | Number of patients (%) | Blood loss (ml) | Total transfusion blood (units) |
No pre-operative treatment | 46 (10.8%) | 480.8 ± 449.9 354 (257.5, 540) | 1.62 ± 7.8 0 (0, 0) |
NOAC | 24 (5.6%) | 542 ±435.6 343.5 (250, 671.5) | 2.62 ± 5.64 0 (0, 3) |
ASA | 346 (81.7%) | 424.8 ±336.8 306.5 (247, 492.8) | 0.60 ± 1.85 0 (0, 0) |
API | 107 (25.9%) | 411.6 ± 309.6 295 (244, 523) | 0.89 ± 1.58 0 (0, 1.25) |
ASA + API | 89 (21 %) | 426.2 ± 334.1 300 (244.5, 530.5) | 0.97 ± 1.56 0 (0, 2) |
P158 Retinal microvascular damage associated with mean arterial pressure during cardiopulmonary bypass surgery
V Shipulin1, M Dyakova1, Y Podoksenov2, E Shishneva2, Y Svirko3, M Denisko4, O Krivosheina4, I Mandel5
1Cardiology Research Institute,, Cardiosurgery, Tomsk, Russia; 2Cardiology Research Institute,, ICU, Tomsk, Russia; 3Cardiology Research Institute,, Laboratory, Tomsk, Russia; 4Siberian State Medical University, Ophthalmology, Tomsk, Russia; 5Sechenov University, Anesthesiology and Intensive Care, Moscow, Russia
P159 Atrial fibrillation after cardiac surgery: implementation of a prevention care bundle on intensive care unit improves adherence to current perioperative guidelines and reduces incidence
M Buerge1, R Magboo2, D Wills3, I Karpouzis4, P Cooper5, D Balmforth6, N Roberts6, B O´Brien3
1Royal Papworth Hospital NHS Trust, Anaesthesia and Intensive Care, Cambridge, United Kingdom; 2St Bartholomew´s Hospital, Barts Heart Centre, Adult Critical Care Unit, London, United Kingdom; 3St Bartholomew´s Hospital, Barts Heart Centre, Perioperative Medicine, London, United Kingdom; 4Gennimatas General Hospital, Cardiology, Athens, Greece; 5St Bartholomew´s Hospital, Barts Heart Centre, Pharmacy, London, United Kingdom; 6St Bartholomew´s Hospital, Barts Heart Centre, Cardiothoracic Surgery, London, United Kingdom
P160 Use of hypoxic gas mixture in neonates with single ventricle physiology prior to the Norwood procedure
V Sheward, E Al Mahmoud, K Ramakrishnan
Sheikh Khalifa Medical City Hospital, PCICU, Abu Dhabi, United Arab Emirates
P161 Multimodal analgesia in neurocritical care patients: complementing therapies to reduce the use of endovenous opioids
M Canitrot1, J Ramirez2, J Serra3, Y Santos3, V Munoz3, F Paravic4, S Ugarte3
1INDISA CLINIC, Critical Care, Santiago, Chile; 2Andres Bello University, NeuroICU, Santiago, Chile; 3INDISA CLINIC, NeuroICU, Santiago, Chile; 4INDISA CLINIC, Neurorehabilitation, Santiago, Chile
P162 Assessment-driven, protocol-based pain management post cardiac surgery significantly improves measured pain scores
I Charles, A Johnson, M Govender, M Stevens, M Gohobur, CY Kim, L Campbell, EE Quaynor, H Hideg, G Zilahi
St George´s University Hospital NHS Foundation Trust, CTICU, London, United Kingdom
P163 Compartment psoas block efficacy for perioperative analgesia in the elderly with proximal femur fractures
K Bielka, I Kuchyn, I Tokar
Bogomolets National medical university, Postgraduate surgery, anesthesiology and intensive care, Kyiv, Ukraine
P164 Evaluation of safety and efficacy of concomitant parenteral olanzapine and benzodiazepine for agitation
HH Huynh, TS Lam, JT Jancik, G Betterman
Hennepin County Medical Center, Clinical Pharmacy, Minneapolis, United States
Primary Outcomes | Initial | Post | Difference |
---|---|---|---|
SBP, median (IQR), mm Hg | 130 (119-145) | 125 (109-136) | -5 |
Vasopressor support | -- | 0/208 (0%) | -- |
Mechanical ventilation for respiratory depression | -- | 6/208 (2.9%) | -- |
Secondary Outcomes | |||
Olanzapine, mean, mg | -- | 11.8 | -- |
Midazolam equivalent, median (IQR), mg | -- | 5 (4-5) | -- |
P165 Could preoperative US guided fascia iliaca compartment block (FICB) decrease opioid consumption and perioperative morbidity of elderly patients with hip surgery for femoral fracture?
D Pavelescu1, I Grintescu2
1Emergency Hospital Floreasca, Anesthesiology and Intensive Care, Bucharest, Romania; 2Emergency Hospital Floreasca, Intensive Care and Anesthesiology, Bucharest, Romania
P166 Pain assessment in chronic disorders of consciousness patients with ANI monitoring
E Kondratyeva, M Aybazova, N Dryagina
Almazov National Medical Reseach Centre, Minimally conscious research group, St Petersburg, Russia
P167 Hemodynamic effects of dexmedetomidine in patients with septic shock: a cohort study of the sedation practice in intensive care evaluation [SPICE III] trial
L Cioccari1, N Luethi2, M Bailey2, A Messmer1, L Peck3, B Howe2, Y Shehabi4, J Takala1, S Jakob1, R Bellomo3
1University Hospital and University of Bern, Department of Intensive Care Medicine, Bern, Switzerland; 2School of Public Health and Preventive Medicine, Monash University, Australian and New Zealand Intensive Care Research Centre, Melbourne, Australia; 3Austin Hospital, Department of Intensive Care Medicine, Heidelberg, Australia, 4School of Clinical Sciences, Monash University, Monash Health, Critical Care and Perioperative Services, Melbourne, Australia
P168 Multimodal analgesia with low dose of ketamine and dexamethasone, an interesting option for patients with total hip arthroplasty?
D Pavelescu1, I Grintescu2
1Emergency Hospital Floreasca, Anesthesiology and Intensive Care, Bucharest, Romania; 2Emergency Hospital Floreasca, Intensive Care and Anesthesiology, Bucharest, Romania
P169 Analgesia usage in ICU survivors
P Mactavish1, C Pudrie2, M Shaw3, P Henderson2, H Devine4, T Quasim5, J Iwashyna6, J McPeake4
1Glasgow Royal Infirmary, Pharmacy, Glasgow, United Kingdom; 2University of Glasgow, School of Medicine, Dentistry and Nursing, Glasgow, United Kingdom; 3NHS Greater Glasgow and Clyde, Clinicial Physics, Glasgow, United Kingdom; 4Glasgow Royal Infirmary, Intensive Care Unit, Glasgow, United Kingdom; 5University of Glasgow, School of Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom; 6VA Ann Arbor Health System, Centre for Clinical Management Research, Ann Arbor Michigan, United States
P170 Impact of a multifaceted and multidisciplinary intervention on pain, agitation, and delirium management in a Canadian community ICU: a quality improvement study
Z Ma1, M Carmargo Penuela2, M Law2, HO Chung3, J Tsang3
1McMaster University, NIagara Regional Campus, Michael G. DeGroote School of Medicine, St. Catharines, Canada; 2Brock University, Department of Health Science, St. Catharines, Canada; 3McMaster University, Division of Critical Care, Hamilton, Canada
P171 Oversedation and ICU-acquired delirium: an observational study
M Marchesi1, N Latronico1, F Terranova1, S Sala1, M Brognoli2, GP Nocivelli2, R Bertuetti2, E De Peri2, F Rasulo1
1Università degli studi di Brescia, Anestesia e Rianimazione, Brescia, Italy; 2Spedali Civili di Brescia, Anestesia e Rianimazione, Brescia, Italy
P172 Predictors of delirium after myocardial infarction, insights from a retrospective registry
M Jäckel, V Zotzmann, T Wengenmayer, D Dürschmied, C Von zur Mühlen, P Stachon, C Bode, DL Staudacher
Heart Center Freiburg University, Department of Cardiology and Angiology I, Freiburg, Germany
P173 Incidence and risk factors of delirium in surgical intensive care unit
MA Ali, B Saleem
Aga Khan University, Anaesthesia, Karachi, Pakistan
P174 Evaluation of delirium risk factors in intensive care patients
S Erel1, E Macit Aydın1, B Nazlıel2, L Karabıyık1
1Gazi University School of Medicine, Anesthesiology and Intensive Care, Ankara, Turkey; 2Gazi University School of Medicine, Neurology and Intensive Care, Ankara, Turkey
P175
P176 Delirium tremens in ICU: a descriptive study of clinical practices and patients complications
M Geslain, J Le Roy, P Aries, X Chapalain, T Gargadennec, O Huet, E L´Her, P Bailly
CHRU Brest, Brest, France
- Need for mechanical ventilation due to unmanageable agitation or acute respiratory distress (33% of the patients)
- Self inflicted injuries such as pulling out of central lines, tubes, surgical drain (46%)
- Falls (7%).
- Seizures (33%).
P177 The incidence and related risk factor of delirium in surgical stepdown unit
S Yoon1, S Yang2, G Cho2, H Park2, K Park2, J Ok2, Y Jung2
1Asan medical center, Nursing department, Seoul, South Korea; 2Asan Medical Center, Seoul, South Korea
P178 Validation of the prediction model for delirium in ICU patients (pre-deliric model) in mechanically ventilated Japanese patients with sepsis
K Miyamoto1, T Nakashima1, N Shima1, S Kato1, Y Kawazoe2, Y Ohta3, T Morimoto4, H Yamamura5
1Wakayama Medical University, Department of Emergency and Critical Care Medicine, Wakayama, Japan; 2Tohoku University Graduate School of Medicine, Division of Emergency and Critical Care Medicine, Sendai, Japan; 3Hyogo College of Medicine, Division of General Medicine, Department of Internal Medicine, Nishinomiya, Japan; 4Hyogo College of Medicine, Department of Clinical Epidemiology, Nishinomiya, Japan; 5Osaka Prefectural Nakakawachi Emergency and Critical Care Center, Higashiosaka, Japan
P179 The effect of dexmedetomidine on the duration of delirium and the use of narcotic analgesics in elderly patients with femur fracture
A Konkayev1, N Bekamagambetova2, M Konkayeva3
1Astana Medical University, Anaesthesiology and Intensive Care, Nur-Sultan, Kazakhstan; 2Trauma institution, Nur-Sultan, Kazakhstan; 3Astana Medical University, Nur-Sultan, Kazakhstan
P180 Live music therapy in intensive care unit
MC Soccorsi1, C Tiberi1, G Melegari1, J Maccieri2, F Pellegrini2, E Guerra1, A Marudi1, E Bertellini1
1Policlinico Teaching Hospital, Modena, Department of Anaesthesia and Intensive Care, Modena, Italy; 2Policlinico Teaching Hospital, Modena, School of Anaesthesia and Intensive Care, Modena, Italy
P181 Medical hypnosis and virtual reality glasses are safe and effective tools to alleviate pain and anxiety in patients undergoing medical procedures
EK Okur kavak1, G Van Berlaer2, M Diltoer1, M Malbrain1
1Universitair Ziekenhuis Brussel, Intensive Care, Brussels, Belgium; 2Universitair Ziekenhuis Brussel, Emergency and Disaster Medicine, Brussels, Belgium
P182 Music to reduce pain and distress due to emergency care: a randomized clinical trial
NE Nouira, I Boussaid, D Chtourou, S Sfaxi, W Bahria, D Hamdi, M Boussen, M Ben Cheikh
Mongi Slim Academic Hospital, Emergency Department, Tunis, Tunisia
P183 Impact of music therapy as non-pharmacological intervention in patients in weaning from mechanical ventilation
M Carmona1, G Pagella2, G Federico3, R Paffumi1, D Minzer3, G Zakalik1
1Hospital Luis Carlos Lagomaggiore, UCI, mendoza, Argentina; 2Hospital Luis Carlos Lagomaggiore, Terapia intensiva, Mendoza, Argentina; 3Hospital Luis Carlos Lagomaggiore, mendoza, Argentina
P184 Association between severity and coagulopathy in patients with anaphylaxis
S Yamaga1, Y Yanase2, K Ishii2, K Hosokawa1, S Ohshimo1, N Shime1, M Hide2
1Hiroshima University, Department of Emergency and Critical Care Medicine, Hiroshima, Japan, 2Hiroshima University, Department of Dermatology, Hiroshima, Japan
P185 Cardiac manifestations of H1N1 infection in a Greek ICU population
E Nanou1, P Vasiliou1, E Tsigou2, V Psallida1, E Boutzouka2, V Zidianakis1, G Fildissis1
1Agioi Anargiroi Hospital, Attiki, Greece; 2Agioi Anargiroi Hospital, ICU, Attiki, Greece
Elevated troponin | N=7 (77.78%) |
Systolic dysfunction | N=4 (36%) |
ECG abnormalities | N=7 (77.78%) |
CI (l/min/m2) | 2.86±0.13 |
GEF (%) | 20.50±4.95 |
GEDI (ml/m2) | 824±64.1 |
SVRI (dyn/sec/cm/m2) | 2179±339 |
EVLWI (ml/kg) | 11.33±5.13 |
P186 Levosimendan improves oxidative balance in low cardiac output patients
E Grossini1, S Farruggio1, V Bolzani2, L Rossi2, E Monaco3, P Pollesello4
1Università Del Pienmonte Orientale, Department of Translational Medicine, Novara, Italy; 2Azienda Ospedaliero Universitaria, Cardiology Division, Novara, Italy; 3Azienda Ospedaliero Universitaria, Intensive Care Unit, Novara, Italy; 4Orion Corporation Orion Pharma, Critical Care Propretary Products, Espoo, Finland
P187 An analysis of the prognostic ability of noradrenaline dose in patients with septic shock
M Chotalia1, M Bangash2, T Matthews2, D Parekh2, J Patel2
1University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom
P188 Early vasopressor use in the emergency department is associated with survival in patients with septic shock
M Chotalia1, M Bangash2, T Matthews2, D Parekh2, J Patel2
1University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom
Survived (n = 49) | Died (n=38) | p value | |
---|---|---|---|
Age (years) | 63.7 (2.6) | 66.0 (2.8) | 0.55 |
Median MAP in ED (mmHg) | 64.5 (1.1) | 63.9 (1.9) | 0.77 |
Fluid given (mls) | 3372 (179) | 3394 (158) | 0.93 |
Vasopressor use in ED (%) | 88.9% (43/49) | 68.4% (26/38) | 0.035 |
Early vasopressor use (%) | 67.3% (33/49) | 42.1% (16/38) | 0.029 |
Time spent in ED (mins) | 401 (27.5) | 427 (38.3) | 0.57 |
Time to ITU review (mins) | 201 (19.4) | 199 (24.1) | 0.94 |
P189 Prevalence and management of tuberculous cardiac tamponade : experience of Casablanca cardiac care unit
R Benmalek1, H Zahidi2, J Hassari3, S Arous3, E Benouna3, R Habbal3
1CHU Ibn Rochd, Cardiology Department, Casablanca, Morocco; 2Cardiology department, CHU Ibn Rochd, Casablanca, zahidi, Casablanca, Morocco; 3Cardiology department, CHU Ibn Rochd, Casablanca, Cardiology, Casablanca, Morocco
P190 Point-of-care ultrasound teaching during anaesthesia and critical care residency: an Italian national survey
F Bonomi, S Mongodi, A Colombo, A Stella, S Pregnolato, G Salve, S Bonaiti, A Orlando, F Mojoli
Fondazione IRCCS Policlinico San Matteo - Università di Pavia, Anaesthesia and Intensive Care, Pavia, Italy
P191 Confirming central line position through bedside ultrasound
JD Dillemans, AD Dumoulin, WS Stockman, PL Lormans
AZ Delta, Intensive Care, Roeselare, Belgium
P192 A systematic review on the comparison of the role of internal jugular vein, inferior vena cava and carotid ultrasound measurements in assessment of patients with heart failure
N Parenti1, F Musto1, V Pezzilli1, G Borelli1, T Rada1, F Agrusta2, S Menetti2, M Nuzzetti2, E Romboli1, M Silingardi1
1Hospital Maggiore, Internal Medicine, Bologna, Italy; 2Policlinico Modena, Internal Medicine, Modena, Italy
P193 Epidemiology of baseline echocardiography among critically ill patients with sepsis
MH Senussi1, JN Kennedy2, M Schmidhofer1, O Marroquin3, DC Angus2, CW Seymour2
1University of Pittsburgh, Heart & Vascular Institute, Pittsburgh, United States; 2University of Pittsburgh, Department of Critical Care Medicine, Pittsburgh, United States; 3University of Pittsburgh, UPMC Department of Clinical Analytics, Pittsburgh, United States
P194 Most guidewires used for central venous catheterization of the right subclavian vein in adults are too short; a CT-based observational study
M Adrian1, P Bengtsson2, O Borgquist1, G Bozovic2, T Kander1
1Skåne University Hospital, Anaesthesia and Intensive Care, Lund, Sweden; 2Skåne University Hospital, Diagnostic Radiology, Lund, Sweden
Manufacturer | Model | Actual guide-wire length (mm)b | Calculated minimal guidewire length (mm)c | Discrepancy (mm) |
---|---|---|---|---|
Arrow, 2-lumen | Blue FlexTip 16 cm | 590 | 506 | 84 |
Bactiguard, 3-lumen | BIP CVC 16 cm | 440 | 513 | -73 |
B Braun, 3-lumen | Certofix 15 cm | 495 | 528 | -33 |
Meritmedical, 3-lumen | Careflow 15 cm | 445 | 535 | -90 |
P195 The reliability of lung B-lines to assess fluid status in patients with long period of supine position
K Mnif1, O Doukali2, E Unluer3, R Ammar2, C Ben hamida2, M Bouaziz2
1University Hospital Habib Bouguiba Sfax, Intensive Care Unit, Sfax, Tunisia; 2university hospital habib bouguiba sfax, intensive care unit, sfax, Tunisia; 3S.B.U Bozyaka Egitim ve Arastirma hastanesi, emergency department, izmir, Turkey
P196 Oblique approach for ultrasound-guided cannulation of femoral vein overlapped by artery
A Kothekar, J George, A Kulkarni, V Patil
Tata memorial center, Homi Bhabha National Institute, Mumbai, India
P197 P wave indices in critically unwell patients with new-onset atrial fibrillation (NOAF)
JT Lay1, B Johnston2, K Williams3, I Welters2
1University of Liverpool, School of Medicine, Liverpool, United Kingdom; 2Royal Liverpool Hospital, Liverpool, United Kingdom, 3University of Liverpool, Institute of Ageing and Chronic Disease, Liverpool, United Kingdom
P198 Measuring peripheral arterial tone and biomarkers to identify endothelial dysfunction
V Schechten1, A Larena-Avellaneda1, B Saugel2, R Schnabel3, L Plümer2, ES Debus1, C Zöllner2, E Schwedhelm4, G Daum1, MS Winkler5
1University Heart Center, Clinic and Policlinic for Vascular Medicine, Hamburg, Germany; 2University Medical Center Hamburg-Eppendorf, Center for Anesthesiology and Intensive Care Medicine, Hamburg, Germany; 3University Heart Center, Clinic and Policlinic for Cardiology, Hamburg, Germany; 4University Medical Center Hamburg-Eppendorf, Institute of Clinical Pharmacology and Toxicology, Hamburg, Germany; 5University Medicine Göttingen, Department of Anesthesiology and Intensive Care Medicine, Göttingen, Germany
P199 Single-lumen 5Fr and triple-lumen 6Fr peripherally inserted central catheters (PICCs) for cardiac output assessment by transpulmonary thermodilution
S D´Arrigo1, C Sandroni1, S Cacciola1, AM Dell´Anna1, M Pittiruti2, MG Annetta1, G Chiuri1, M Antonelli1
1Fondazione Policlinico Universitario A. Gemelli IRCCS, Department of Anesthesiology, Intensive Care and Emergency Medicine, Rome, Italy; 2Fondazione Policlinico Universitario A. Gemelli IRCCS, Department od Surgery, Rome, Italy
P200 Pilot study: Advanced hemodynamic monitoring after acute spinal cord injury
N Drotleff1, O Jansen1, M Aach2, TA Schildhauer1, C Waydhas1, U Hamsen1
1BG University Hospital Bergmannsheil, Department of General and Trauma Surgery, Bochum, Germany; 2BG University Hospital Bergmannsheil, Department of Spinal Cord Injury, Bochum, Germany
P201 Establishing a focused critical care echocardiography programme in a developing world intensive care unit
D Hall1, J Harrington1, M Murali2, TY Wang2, N Shamambo2
1Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 2University Teaching Hospital, Lusaka, Zambia
P202 Association of thermodilution-derived cardiac index, stroke volume index and heart rate with hospital mortality in ICU patients: an observational study
LR Rapp, TL Lahmer, MH Heilmaier, GB Batres-Baires, RS Schmid, WH Huber
Klinikum Rechts der Isar der technischen Universität München, Medizinische Klinik und Poliklinik II, München, Germany
P203 An evaluative study of the novelty device with the function of auto-aspirating and pressure indicator for safety central venous catheterization
LY Lin, WF Luo, CY Tsao
National Taiwan University Hospital, Taipei, Taiwan
P204 Cross-correlation features of vital signs enable robust detection of hemorrhage
V Jeanselme1, A Wertz1, G Clermont2, MR Pinsky2, AW Dubrawski1
1Carnegie Mellon University, Auton Lab, School of Computer Science, Pittsburgh, United States; 2University of Pittsburgh, School of Medicine, Pittsburgh, United States
P205 Hemoguide: a new tool for decision-making support in critically ill patients
A Minini1, SG Sakka2, FJ Belda3, M Kirov4, JL Teboul5, W Huber6, A Perel7, E Fernández-Mondéjar8, Z Molnar9, ML Malbrain1
1University Hospital Brussels (UZB), Intensive Care Medicine, Brussels, Belgium; 2Universität Witten/Herdecke, Anaesthesiology and Intensive Care Medicine, Witten, Germany; 3Hospital Clinico Universitario, Anaesthesiology and Critical Care, Valencia, Spain; 4Northern State Medical University, Anaesthesiology and Intensive Care Medicine, Arkhangelsk, Russia; 5Hôpitaux Universitaires Paris-Sud, Médicine Intensive-Réanimation, Le Kremlin-Bicêtre, France; 6Klinikum rechts der Isar der Technischen Universität, Intensive Care Medicine, München, Germany; 7Sheba Medical Center, Anesthesiology and Critical Care, Tel Aviv, Israel; 8Hospital Universitario Virgen de las Nieves, Servicio de Medicina Intensiva, Granada, Spain; 9University of Szeged, Anaesthesiology and Intensive Therapy, Szeged, Hungary
P206 Feedback function contributes to accurate measurement of capillary refill time
R Kawaguchi1, TA Nakada2, M Shinozaki2, T Nakaguchi2, H Haneishi2, S Oda2
1Chiba University, Department of Emergency and Critical Care Medicine, Chiba, Japan; 2Chiba University, Chiba, Japan
P207 Course of conjunctival microcirculatory changes in patients with sepsis
J Simkiene1, Z Pranskuniene2, V Pilvinis3, A Pranskunas4
1Department of Intensive Care Medicine, Lithuanian University of Health Sciences, Intensive Care, Kaunas, Lithuania; 2Department of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania; 3Department of Intensive Care Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania; 4Department of Intensive Care Medicine, Lithuanian University of Health Sciences, Intensive Care, Kaunas, Lithuania
P208 Assessment of right heart function during extracorporeal therapy by modified thermodilution
KF Bachmann1, L Zwicker1, K Nettelbeck1, D Casoni2, PP Heinisch3, H Jenni3, M Haenggi1, D Berger1
1Inselspital Bern, University Hospital, Bern, Switzerland, Department of Intensive Care Medicine, Bern, Switzerland; 2University of Bern, Experimental Surgery Facility (ESF), Department for BioMedical Research Faculty of Medicine, Bern, Switzerland; 3Inselspital Bern, University Hospital, Bern, Switzerland, Department of Cardiaovascular Surgery, Bern, Switzerland
P209 Quantifying systemic congestion with point-of-care ultrasound: development of the Venous Excess Ultrasound Score
W Beaubien-Souligny1, P Rola2, K Haycock3, J Bouchard4, Y Lamarche5, R Spiegel6, A Denault7
1Centre Hospitalier de l´Université de Montréal (CHUM), Nephrology, Montréal, Canada; 2Washington Hospital Center, Division of Intensive Care, Washington DC, United States; 3Washington Hospital Center, Department of Emergency Medicine, Loma Linda University School of Medicine, Washington DC, United States; 4Washington Hospital Center, Division of Nephrology, Washington DC, United States; 5Washington Hospital Center, Department of Surgery and Critical Care, Washington DC, United States; 6Washington Hospital Center, Departments of Critical Care and Emergency Medicine, Washington DC, United States; 7Washington Hospital Center, Department of Anesthesiology and Intensive Care, Washington DC, United States
P210 Comparison of superior vena cava & inferior vena cava diameter changes by echocardiography in predicting fluid responsiveness in mechanically ventilated patients
V Upadhyay1, SS Nath1, M Tripathi1, D Malviya1, A Jha2
1Dr Ram Manohar Lohia Institute Of Medical Sciences, Department Of Anesthesia And Critical Care, Lucknow, India; 2Dr Ram Manohar Lohia Institute Of Medical Sciences, Department Of Cardiology, Lucknow, India
P211 Changes in the microvascular bed availability as an index of fluid loading
LR Ramahi1, CM Maimone2, VG Giammatteo2, RD De Blasi2
1Sant’Andrea University Hospital- Sapienza University of Rome, Italy, Intensive Care, Rome, Italy; 2Sant’Andrea University Hospital- Sapienza University of Rome, Italy, Rome, Italy
P212 Prediction of post-induction hypotension associated with general anesthesia using point-of-care cardiac ultrasound: the value of two dynamic markers of fluid responsiveness
Y Aissaoui
Avicenna Military Hospital - Caddi Ayyad University, Department of Anesthesiology and Intensive Care, Marrakech, Morocco
P213 Pleth varisbility index (PVI) vs. pulse pressure variation (PPV) and stroke volume variation (SVV): an observational study on agreement with PVI including a derivation of comparable thresholds. The Climate-III study
L Offman, U Mayr, T Lahmer, R Schmid, W Huber
Klinikum rechts der Isar, Klinik und Poliklinik für Innere Medizin II, München, Germany
P214 Preload responsiveness can be detected by mini and micro fluid challenges monitored with pulse contour analysis
N De Vita, F Gavelli, JL Teboul, A Beurton, A Pavot, R Shi, X Monnet
Hôpital de Bicêtre, Service de médecine intensive-réanimation, Le Kremlin-Bicêtre, France
P215 The applicability of fluid responsiveness indices in circulatory failure (AFRIC study)
R Shi, N De Vita, F Gavelli, JL Teboul, A Pavot, S Carelli, X Monnet
Hôpital de Bicêtre, Hôpitaux universitaires Paris-Saclay, Le Kremlin-Bicêtre, Service de médecine intensive-réanimation, Paris, France
P216 A modified version of the bioreactance device reliably detects preload responsiveness through the end-expiratory occlusion test
F Gavelli, A Beurton, JL Teboul, N De Vita, R Shi, A Pavot, X Monnet
Hôpital de Bicêtre, Service de Médecine Intensive-Réanimation, Le Kremlin-Bicêtre, France
P217 Detection of the effects of the end-expiratory occlusion test with the plethysmography perfusion index to detect preload responsiveness
A Beurton1, F Gavelli2, JL Teboul2, N De Vita2, X Monnet2
1Hôpital de Bicêtre, Service de réanimation médicale, Inserm UMR S_999, Université Paris-Sud, Assistance Publique Hôpitaux de Paris, Service de réanimation médicale, Inserm UMR S_999, Université Paris-Sud,, Le Kremlin Bicêtre, France; 2Hôpital de Bicêtre, Service de réanimation médicale, Inserm UMR S_999, Université Paris-Sud, Assistance Publique Hôpitaux de Paris, Le Kremlin Bicêtre, France
P218 Does the infusion speed impact the hemodyamic effect of a fluid bolus in septic shock patients? A pharmacodynamic study
AP Pavot, F Gavelli, JL Teboul, S RUI, D Vimpere, I Adda, L Guerin, X Monnet
Bicetre Hospital, Medical Intensive Care, Le Kremlin-Bicêtre, France
P219 Fluid management in the control arm of sepsis trials
AA Anparasan, AC Gordon, MK Komorowski
Imperial College London, Department of Surgery and Cancer, London, United Kingdom
P220 Fluid bolus resuscitation in pediatric sepsis presenting to community hospitals
IV Evans, J Kennedy, J Carcillo, DC Angus, CW Seymour
University of Pittsburgh, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Pittsburgh, United States
P221 Fluid balance in standard of care treatment in patients with sepsis/septic shock
I Douglas1, P Alapat2, K Corl3, L Forni4, M Exline5, A Holder6, A Khan7, J Sahatjian8, W Self9, D Hasell10
1Denver Health Medical Center, Denver, United States; 2Ben Taub Hospital, Houston, United States; 3Rhode Island Hospital, Providence, United States; 4Royal Surrey Hospital, Guilford, United States; 5Ohio State University, Ohio, United States; 6Emory University, Atlanta, United States; 7Oregon Health and Sciences University, Oregon, United States; 8Cheetah Medical, Newton Center, United States; 9Vanderbilt University, Nashville, United States; 10Massachusetts General Hospital, Boston, United States
P222 Trends of serum albumin in septic and non-septic critically ill patients
A Waite1, T Steele2, M Mogk3, I Welters2
1Royal Liverpool University Hospital, Intensive Care, Liverpool, United Kingdom; 2Royal Liverpool University Hospital, Liverpool, United Kingdom; 3Moredata GmbH, Moredata GmbH, Giessen, Germany
P223 Albumin recruits the microcirculation of burn patients with shock
O Dilken1, A Dijkstra2, G Guven1, C Ince1, N Trommel3, M Van Baar3, K Van der Vlies3
1Erasmus MC, Department of Intensive Care, Rotterdam, Netherlands; 2Maasstad Ziekenhuis, Intensive Care Burn Unit, Rotterdam, Netherlands; 3Maasstad Ziekenhuis, Department of Burn Unit, Rotterdam, Netherlands
P224 Early albumin infusion leads to a shorter hospital stay in cirrhotic patients hospitalized with spontaneous bacterial peritonitis: real-world evidence in the United States
WR Kim1, K Raghunathan2, G Martin3, EA Davis4, N Sindhwani4, S Telang5, K Lodaya5
1Stanford University School of Medicine, Stanford, United States; 2Duke University, Durham, United States; 3Emory University, Atlanta, United States; 4Grifols, Research Triangle Park, United States, 5Boston Strategic Partners, Inc., Boston, United States
P225 Early albumin use in patients with septic shock is associated with a shorter hospital stay: real-world evidence in the United States
G Martin1, J Kempker1, K Raghunathan2, EA Davis3, N Sindhwani3, S Telang4, K Lodaya4
1Emory University, Atlanta, United States; 2Duke University, Durham, United States; 3Grifols, Research Triangle Park, United States; 4Boston Strategic Partners, Inc., Boston, United States
P226 Minute-to-minute urine flow rate and urine flow rate variability fluctuations during septic event in critically ill patients
E Brotfain
Ben Gurion University of the Negev, Department of Anesthesiology and Critical Care, Beer Sheva, Israel
P227 Impact of urinary output on incidence and 30-day mortality of acute kidney injury during ICU admission
J Montomoli1, G Guven2, F Termorshuizen3, F Raiez3, MP Hilty4, A Donati5, NF De Keizer3, C Ince2
1Academic Medical Center, Department of Translational Physiology, Amsterdam, Netherlands; 2University Medical Center Rotterdam, Department of Intensive Care, Erasmus MC,, Rotterdam, Netherlands; 3Amsterdam Public Health Institute, AmsterdamUMC, Department of Medical Informatics, Amsterdam, Netherlands; 4University Hospital of Zurich, Institute of Intensive Care Medicine, Zurich, Switzerland; 5Università Politecnica delle Marche, Ancona, Italy, Anesthesia and Intensive Care, Department of Biomedical Sciences and Public Health, Ancona, Italy
P228 Furosemide stress test predicts the progression of acute kidney injury
W Farouk1, H Saber1, M Bayoumy2, H Khaled1
1Faculty of Medicine Cairo university, Critical Care Medicine, Cairo, Egypt; 2Nasser institute, Critical Care Medicine, Cairo, Egypt
P229 Furosemide does not protect the kidney from ischemia reperfusion injury
B Ergin, O Dilken, C Ince
Erasmus MC, Department of Intensive Care, Rotterdam, Netherlands
P230 Acute renal failure induced by hypoxemia: incidence and correlation study
A Trifi1, H Fazzeni2, A Mehdi2, C Abdennebi2, F Daly2, Y Touil2, S Abdellatif2, S Ben Lakhal2
1La Rabta hopital, Medical intensive care unit., Tunis, Tunisia; 2La Rabta hopital, Tunis, Tunisia
P231 Metformin reduces mortality and development of severe AKI in diabetic patients with sepsis
G Del Rio-Pertuz1, CL Manrique-Caballero2, P Priyanka2, CH Chang2, R Murugan2, BS Zuckerbraun3, DC Angus4, JA Kellum2, H Gomez2
1Center for Critical Care Nephrology, The CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Department of Critical Care Medicine, Pittsburgh, United States; 2Center for Critical Care Nephrology, The CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, United States; 3Department of Surgery, University of Pittsburgh, Pittsburgh, United States; 4Department Of Critical Care Medicine, University of Pittsburgh, Pittsburgh, United States
P232 Development and internal validation of a model to predict acute kidney injury recovery at hospital discharge
CY Huang, F Güiza Grandas, M Schetz, J Gunst, M Casaer, G Van den Berghe, G Meyfroidt
KU Leuven, Laboratory of Intensive Care Medicine, Leuven, Belgium
P233 Sepsis induced acute kidney injury: incidence, risk factors and prognostic impact in critically ill patients
K Mnif1, R Ammar2, M Bahloul2, O Doukali2, C Ben Hamida2, M Bouaziz2
1University Hospital Habib Bouguiba Sfax, Intensive Care Unit, Sfax, Tunisia; 2university hospital habib bouguiba sfax, intensive care unit, sfax, Tunisia
P234
P235 Contrast induced acute kidney injury (CIAKI) – fact or fable?
P Pekic1, M Percic2, D Ljubas3, M Mackovic4, N Maric4
1Univ. Hospital “Sveti Duh”, Department for cardiovascular disease - Cardiac intensive care and arrhythmology unit, Zagreb, Croatia; 2Univ. Hospital “Sveti Duh”, Zagreb, Croatia; 3Institute for Emergency Medicine of Zagreb County, Zagreb, Croatia; 4Univ. Hospital “Sveti Duh”, Intensive Care Unit, Zagreb, Croatia
P236 Estimating the GFR and predicting the AKI in cardiac surgery patients: role of bioelectrical impedance derived fat free mass
V Vicka, E Januskeviciute, J Krauklyte, D Ringaitiene, J Sipylaite
Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Department of Anesthesiology and Intensive Care, Vilnius, Lithuania
P237 RetroAKI: a ten-year retrospective study of acute kidney injury in intensive and progressive care units
A Gardon, VZ Zorio, MB Bodinier, MD Dutour, CM Monard, JC Crozon, GM Marcotte, JT Textoris, TR Rimmelé
Edouard Herriot Hospital, Hospices Civiles de Lyon, Department of Intensive Care, 5 Place d´Arsonval, France
ICU (n = 12356) | PCU (n = 6019) | |
---|---|---|
No AKI (%) | 25.4 | 56 |
AKI stage 1 (%) | 25.4 | 24.4 |
AKI stage 2 (%) | 23.6 | 15 |
AKI stage 3 (%] | 25.5 | 4.6 |
AKI (%) | 74.6 | 44 |
Severe AKI (%) | 49.2 | 19.6 |
P238 Epidemiology and outcomes of infection in AKI patients
S Cattoir1, P Depuydt1, L De Bus1, E Hoste2
1Ghent University Hospital, Dept. of Intensive Care Medicine, Ghent, Belgium; 2Ghent University Hospital, Dept. of Intensive Care Medicine/Research Foundation Flanders (FWO), Ghent, Belgium
P239 Prediction of outcome by routine measurement based of TIMP-2 (tissue inhibiting metalloproteinase 2) and IGFBP7 (insulin-like growth factor binding protein 7) by NephrocheckTM
V Eising, A Beitz, B Henschel, M Messer, T Lahmer, RM Schmid, W Huber
Klinikum rechts der Isar der TU München, II Medizinische Klinik und Poliklinik, München, Germany
P240 The role of renal artero-venous coupling (RAVC) in the prediction of acute kidney injury in post-surgical critical care patients
L Tecchi1, S Maiorano1, C Brusasco2, F Forfori1, F Corradi3
1Azienda Ospedaliero Universitaria Pisana, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy., Pisa, Italy; 2Ospedali Galliera. Mura delle Cappuccine 14, 2. Anaesthesia and Intensive Care Unit, E.O. Ospedali Galliera, Genova, Italy., Genova, Italy; 3Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
P241 Influence of urinary creatinine excretion on augmented creatinine clearance in critically ill patients
C Mendes Silva, JP Baptista, P Martins
Centro Hospitalar e Universitário de Coimbra, Serviço de Medicina Intensiva, Coimbra, Portugal
P242 Long-term outcomes of community- versus hospital-acquired acute kidney injury: a retrospective analysis of a large cohort in a German tertiary care center
D Khadzhynov1, L Lehner2, D Schmidt2, K Eckardt2, K Schmidt-Ott2
1Charité Universitätsmedizin Berlin, Department of Nephrology and Internal Intensive Care, Berlin, Germany; 2Charité Universitätsmedizin Berlin, Medical Department, Division of Nephrology and Internal Intensive Care Medicine, Berlin, Germany
P243 Fluid removal practices during renal replacement therapy – a European survey of critical care practitioners
N Seylanova1, L Tovey2, P McCready2, R Murugan3, M Ostermann2
1Sechenov First Moscow State Medical University, Moscow, Russia; 2Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom; 3University of Pittsburgh School of Medicine, Pittsburgh, United States
P244 Comparing of regional citrate and systemic heparin anticoagulation methods in continuous renal replacement therapies on critically ill patients
P Kucukdemirci kaya, FS Kahveci, P Rahimi, N Kelebek Girgin, R Iscimen
Bursa Uludag University, Anesthesiology and Intensive Care, Bursa, Turkey
Gender (F/M) | 4/7 | ||
Age (year) | 57,9±20,1 | ||
SOFA score (during first CRRT) | 11,3±4,9 | ||
Sepsis (n) | 10 | ||
Cirrhosis (n) | 2 | ||
UFH | RCA | p-value | |
Mean filter life time (hour) | 40,5±38,9 | 67,8±29,8 | <0,001 |
Mean ultrafiltration flow (ml/hour) | 81,4±39,6 | 118,2±51,4 | <0,001 |
P245 Regional citrate anticoagulation during CRRT in liver failure
MJ Jain, PK Kumar G, DG Govil, JK KN, SP Patel, MS Shafi, RH Harne, DP Pal, SM Monanga
Medanta the Medicity, Critical Care, Gurugram, India
P246 Optimising regional citrate anticoagulation (RCA) in continuous renal replacement therapy (CRRT): a pre-study of complications and citrate loads
N Hussain, I Carrasco
Barking, Havering and Redbridge University Hospitals NHS Trust, Critical Care Department, London, United Kingdom
P247 Delta-pH unmeasured anion: a predictor for starting continuous renal replacement therapy in acute kidney injury
B Gucyetmez1, ZT Sarikaya2, F Tuzuner3, IO Akinci4, L Telci5, F Toraman6
1Acıbadem Mehmet Ali Aydınlar University School of Medicine, Department of Anesthesiology and Reanimation, Istanbul, Turkey; 2Acıbadem Mehmet Ali Aydınlar University School of Medicine, Department of Anesthesiology and Reanimation, Istanbul, Turkey; 3Taksim Acıbadem Hospital, General Intensive Care Unit, Istanbul, Turkey; 4Altunizade Acıbadem Hospital, General Intensive Care Unit, Istanbul, Turkey; 5Acıbadem International Hospital, General Intensive Care Unit, Istanbul, Turkey; 6Acıbadem Mehmet Ali Aydınlar University School of Medicine, Department of Anesthesiology and Reanimation, Istanbul, Turkey
P248 Initiatives to enhance standard, workflow and nursing competence in delivery of safe continuous renal replacement therapy
YC Wong, WT Yeung, PO Lei, PK Chan, YC Chiu, SY Chu, SC Chin, WS Shum
Ruttonjee & Tang Shiu Kin Hospitals, Cardiac & Intensive Care Unit, Hong Kong SAR, Hong Kong
P249 Does hemoperfusion therapy affect survival in patients with sepsis?
C Balci1, E Haftaci2, H Karaca3, E Karaca3
1Kutahya Healty Science Un, Anaesthesiology and Reanimation, Kutahya, Turkey; 2Karaman Goverment Hospital, Intensive Care, Karaman, Turkey; 3Derince Traning Hospital, Anaesthesiology and Reanimation, Kocaeli, Turkey
P250 Immunomodulation in septic shock with an endotoxin removal device
SA Shlyapnikov1, MI Gromov2, AV Fedorov2, LP Pivovarova3, ME Malyshev3, OB Ariskina3, IV Osipova3
1Federal State Budgetary Institution “Saint Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine”, department of emergency gastroenterology, Saint-Petersburg, Russia; 2Federal State Budgetary Institution “Saint Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine”, department of efferent therapy, Saint-Petersburg, Russia; 3Federal State Budgetary Institution “Saint Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine”, department of laboratory diagnostics, Saint-Petersburg, Russia
P251 Does the endotoxin adsorption of PMX column saturate in 2 hours? Preliminary study
C Yamashita1, K Moriyama2, D Hasegawa1, T Kawaji1, N Kuriyama1, T Nakamura1, Y Shimomura1, S Suzuki1, Y Kato1, O Nishida1
1Fujita Health University School of Medicine, Department of Anesthesiology and Critical Care Medicine, Toyoake, Japan; 2Fujita Health University School of Medicine, Laboratory for Immune Response and Regulatory Medicine, Toyoake, Japan
P252
P253 CRRT with the oXiris filter in septic patients with AKI: effect of the basal AKIN stage
F Turani1, S Busatti2, S Martini3, F Gargano4, M Falco4, L Weltert5, M Dauri6, P Caravetta7
1Aurelia Hospital, Anesthesia and Intensive Care, Rome, Italy; 2Aurelia Hospital, Rome, Italy; 3Aurelia Hospital, Anesthesia And Intensive Care, Rome, Italy; 4European Hospital, Anesthesia And Intensive Care, Rome, Italy; 5European Hospital, Cardiac Surgery, Rome, Italy; 6University Tor Vergata, Anesthesia And Intensive Care, Rome, Italy, 7Ospedale S Camillo, Anesthesia And Intensive Care, Rome, Italy
P254 A non-interventional, multicenter, non-randomized patient registry for multiple organ dialysis with the ADVOS system: 2-year interim analysis in 118 patients
V Fuhrmann1, A Perez2, A Faltlhauser3, B Tyczynski4, D Jarczak1, J Lutz5, J Weinmann-Menke6, W Huber7, A Kribben4, S Kluge1
1Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2ADVITOS GmbH, München, Germany; 3First Department of Internal Medicine, Kliniken Nordoberpfalz AG, Klinikum Weiden, Weiden, Germany; 4Klinik für Nephrologie, Universität Duisburg-Essen and Universitätsklinikum Essen, Essen, Germany; 5Medical Clinic, Nephrology-Infectious Diseases, Gemeinschaftsklinikum Mittelrhein, Koblenz, Germany; 6Division of Nephrology, I. Department of Medicine, University Medical Center Mainz, Mainz, Germany; 7Medizinische Klinik und Poliklinik II, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
Parameter | Before 1st ADVOS | After 1st ADVOS | p-value |
---|---|---|---|
Bilirubin total [mg/dl] | 11.2 ± 1.2 | 9.2 ± 0.8 | <0.001 |
Creatinine [mg/dl] | 1.9 ± 0.2 | 1.4 ± 0.1 | <0.001 |
BUN [mg/dl] | 32 ± 3 | 20 ± 2 | <0.001 |
pH | 7.33 ± 0.01 | 7.40 ± 0.01 | <0.001 |
HCO3 [mmol/l] | 21.3 ± 0.6 | 25.5 ± 0.7 | <0.001 |
Base Excess [mmol/l] | -4.5 ± 0.8 | 1.0 ± 0.8 | <0.001 |
Platelets [/nl] | 129 ± 15 | 100 ± 13 | <0.001 |
P255 Cyclosporine does not affect cytokine release in response to extracorporeal circulation in coronary artery bypass grafting
EG Grins1, SJ Jovinge2
1Skåne University Hospital, Lund, Department of Cardiothoracic Surgery, Anesthesia and Intensive Care, Lund, Sweden; 2Fredrik Meijer Heart and Vascular Institute, Spectrum Health, Fredrik Meijer Heart and Vascular Institute, Grand Rapids, Michigan, United States
P256 New generation adsorbent in hemofiltration helps reducing inflammatory response in septic shock patient
M Cindryani1, V Irawany2, M Taufik2
1Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 2Fatmawati Hospital, Jakarta, Indonesia
P257 Influence of complications of diabetic ketoacidosis treatment on length of stay at intensive care unit
D Adukauskiene, L Jazokaite, R Verkauskiene
Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania
P258 Central venous-arterial PCO2 difference to arterio-venous oxygen content difference ratio, Pcv-aCO2/Ca-cvO2, in patients with metformin associated lactic acidosis (MALA): a marker of anaerobic metabolism?
A Casazza1, E Bellazzi2, D Ciprandi2, R Preda2, R Vanzino2, L Carnevale2
1ASST Pavia, Anaesthesia and Intensive Care Vigevano, Vigevano, Italy; 2ASST Pavia, Vigevano, Italy
P259 Early versus delayed administration of basal insulin in diabetic ketoacidosis: a retrospective study
M Dustrude, TS Lam, JT Jancik
Hennepin County Medical Center, Pharmacy, Minneapolis, United States
P260 Glycaemic control in critically ill patients – a work in progress
M Andonovic, A Kinsey, H Browne, P O´Neil, R Sundaram
Royal Alexandra Hospital, Department of Intensive Care, Paisley, United Kingdom
P261 Time in blood glucose range 110 to 179 mg/dl > 80% is associated with survival rate in critically ill patients
H Naraba1, H Nakano2, Y Takahashi2, T Sonoo2, H Hashimoto2, K Nakamura2
1Hitachi General Hospital, Department of Emergency and Critical Care Medicine, Ibaraki, Japan; 2Hitachi General Hospital, Ibaraki, Japan
P262 Prevalence and impact of chronic dysglycemia in intensive care unit patients
A Balintescu1, I Palmgren2, M Lipcsey3, A Oldner4, A Larsson5, M Cronhjort6, M Lind7, J Wernerman8, J Mårtensson4
1Karolinska Institutet Södersjukhuset, Department of Clinical Science and Education, Stockholm, Sweden; 2Hudiksvall Hospital, Department of Anesthesia and Intensive Care, Hudiksvall, Sweden; 3Uppsala University, Hedenstierna Laboratory, Department of Surgical Sciences, Section of Anaesthesiology and Intensive care, Uppsala, Sweden; 4Karolinska Institutet, Department of Physiology and Pharmacology, Stockholm, Sweden; 5Uppsala University, Department of Medical Sciences, Clinical Chemistry, Uppsala, Sweden; 6Karolinska Institutet Södersjukhuset, Department of Anesthesia and Intensive Care Södersjukhuset, Stockholm, Sweden; 7Uddevalla University, Department of Medicine, NU Hospital Group, Uddevalla, Sweden; 8Karolinska Institutet, Department of Clinical Science Intervention and Technology, Division of Anaesthesia and Intensive Care, Stockholm, Sweden
P263 Case report: modern antidiabetic therapie causes ketoacidosis
AM Heiden, M Emmerich
Krankenhaus Bad Oeynhausen, Institut für Anästhesie, Bad Oeynhausen, Germany
P264 Unraveling the obesity paradox in the intensive care unit: a causal inference approach
A Decruyenaere1, J Steen1, K Colpaert2, D Benoit2, J Decruyenaere2, S Vansteelandt3
1Ghent University Hospital, Department of Internal Medicine and Pediatrics, Gent, Belgium; 2Ghent University Hospital, Department of Intensive Care Medicine, Gent, Belgium; 3Ghent University, Department of Applied Mathematics, Computer Science and Statistics, Gent, Belgium
P265 Patterns of bowel motions in ICU and the implementation of a stepwise management protocol to reduce decision fatigue
C Cole, H McConnell
Royal Victoria Infirmary, Perioperative and Intensive care, Newcastle upon Tyne, United Kingdom
P266 Ogilvie syndrome in ICU
P Delaney, S Delaney, A Fahy, M Donnelly
Tallaght University Hospital, Intensive Care Department, Dublin, Ireland
P267 Diarrhea in intensive care unit
Z Binici, S Bozbay, O Demirkiran
Istanbul University Cerrahpasa, Anesthesiology and Intensive Care, Istanbul, Turkey
P268 Prognostic value of malnutrition in cardiac surgery. an eight year follow up data
S Efremov1, V Lomivorotov2, P Vedernikov2, T Dzhumatov3, T Ovchinnikov3, A Rashidov3
1Saint Petersburg University Hospital, Anesthesiology and Intensive care, Saint-Petersburg, Russia; 2E. Meshalkin National Medical Research Center, Anesthesiology and Intensive care, Novosibirsk, Russia; 3St. Petersburg State University, Medical faculty, Saint-Petersburg, Russia
P269 The validity of a simple assessment tool for screening sarcopenia in surgical elderly cancer patients
O Chaiwat1, A Siriussawakul1, P Pramyothin2, C Thanakiattiwibun1
1Siriraj Hospital, Anesthesiology, Bangkok, Thailand; 2Siriraj Hospital, Medicine, Bangkok, Thailand
Muscle mass | Muscle strength | Physical performance | Risk of malnutrition & Malnutrition | |
---|---|---|---|---|
AWGS | decrease | decrease | and/or decrease | - |
C1 | - | decrease | and decrease | |
C2 | - | decrease | and decrease | and decrease |
C3 | - | decrease | and/or decrease | and decrease |
C4 (and decrease BMI) | - | decrease | and/or decrease | - |
P270
P271 Enteral glutamine supplementation in critically ill patients with burns
V Bagin, M Astafyeva, I Korobko, E Elmak, A Pushniak, V Rudnov
City Clinical Hospital No 40, ICU, Yekaterinburg, Russia
P272 The effect on ketogenesis of withholding early parenteral nutrition in critically ill children, as a potential mediator of the improved intensive care outcomes
A De bruyn1, J Gunst2, C Goossens2, G Garcia Guerra3, S Verbruggen4, K Joosten4, L Langouche2, G Van den Berghe2
1KU Leuven, Laboratorium of intensive care medicine, Leuven, Belgium; 2KU Leuven, Laboratory of Intensive Care Medicine, Leuven, Belgium; 3University of Alberta, Department of Pediatrics, Edmonton, Alberta, Canada, 4MC Erasmus, Rotterdam, Netherlands
P273 Interruptions of enteral nutrition and energy deficits in critically ill patients. Is still a headache for the ICU physicians? A single-center study
A Kasti1, M Tsirindani2, V Lepouras2, K Katsas2, S Fotiou2, M Tsakoni2, M Lygnos3, MP Almyroudi3, A Armaganidis3, M Theodorakopoulou4
1Department of Nutrition and Dietetics, Attikon University Hospital, Department of Nutrition and Dietetics, Attikon University Hospital, Athens, Greece; 2Department of Nutrition and Dietetics, Attikon University Hospital, Athens, Greece; 32nd ICU Department, Attikon University Hospital, Athens, Greece; 42nd ICU Department, Attikon University Hospital, Intensive Care Medicine, Athens, Greece
P274 Relationship of goal-directed nutritional adequacy with clinical outcomes in critically ill patients
PC Tah1, ZY Lee1, BK Poh2, HA Abdul Majid3, VR Hakumat-Rai4, MB Mat Nor5, CC Kee6, M Kamarul Zaman7, MS Hasan1
1University of Malaya, Department of Anesthesiology, Faculty of Medicine, Kuala Lumpur, Malaysia; 2Universiti Kebangsaan Malaysia, Nutritional Sciences Programme & Centre for Community Health, Faculty of Health Sciences, Kuala Lumpur, Malaysia; 3University of Malaya, Department of Social and Preventive Medicine, Faculty of Medicine, Kuala Lumpur, Malaysia; 4KPJ Tawakkal Specialist Hospital, Kuala Lumpur, Malaysia; 5International Islamic University Malaysia, Department of Anesthesiology, Pahang,, Malaysia; 6National Institutes of Health, Sector for Biostatistics & Data Repository, Research Policy & Planning Division, Selangor,, Malaysia; 7Universiti Teknologi MARA, Centre of Nutrition and Dietetics Studies, Faculty of Health Sciences, Selangor, Malaysia
P275 Terlipressin-induced hyponatremia in acute gastrointestinal bleeding due to portal hypertension
CC Castelo Branco, RA Alves, AP Pinto
Centro Hospitalar e Universitário do Porto, Anesthesiology, Emergency and Critical Care, Porto, Portugal
Na ∆≤-5 mEq | 5 >Na ∆≤ -10 mEq | Na ∆>-10 mEq | p | |
---|---|---|---|---|
Patients, n(%) | 138(72.3) | 39(20.4) | 14(7.3) | |
Length of stay (days), mean(SD) | 4.4(2.3) | 4.5(2.7) | 6.3(2.9) | 0.022 |
Autoimmune hepatitis (AIH), n(%) | 6(4.3) | 0 | 3(21.4) | 0.013 |
Terlipressine cumulative dose (mg), mean(SD) | 33.0(17.4) | 37.8(16.6) | 39.3(14.7) | 0.169 |
Terlipressine duration (days), mean(SD) | 3.3(1.6) | 3.8(1.6) | 3.6(1.0) | 0.124 |
Serum Na admission (mmol/L), mean(SD) | 136.9(4.5) | 140.1(4.7) | 141.8(3.4) | <0.001 |
Mortality, n(%) | 4(2.9) | 0 | 1(7.1) | 0.237 |
P276 An increase in serum sodium predicts mortality in ICU patients
CC Grim1, F Termorshuizen2, HJ Helmerhorst1, NF De Keizer2, E De Jonge1
1Leiden University Medical Center (LUMC), Intensive Care, Leiden, Netherlands; 2Amsterdam University Medical Centre, Medical Informatics, Amsterdam, Netherlands
P277 Variceal bleeding in cirrhotic patients: factors influencing poor outcome. a single-center serie
A Ramos1, E Pizzo1, A Dogliotti2, D Latasa1, M Perezlindo1, S Ferretti3, F Acharta1, C Lovesio1
1Sanatorio Parque, Critical Care, Rosario, Argentina; 2Grupo Oroño, Epidemiology and statistics, Rosario, Argentina; 3Sanatorio Parque, Hepatology, Rosario, Argentina
P278 Impact of acute liver failure on bleeding risk in critical care settings; a multi-center retrospective analysis
Y Yasuda1, D Kasugai2, T Yamamoto2, M Ozaki2, N Matsuda2
1Nagoya University Graduate School of Medicine, Department of Emergency and Critical Care Medicine, Nagoya, Aichi, Japan; 2Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
P279 Potential benefits of hemoadsorption in patients with acute liver failure
M Popescu1, A Vasile2, A Tanase2, A Dinca2, C David2, D Tomescu2
1Fundeni Clinical Institute, Anaesthesia and Critical Care, Bucharest, Romania; 2Fundeni Clinical Institute, Bucharest, Romania
P280 Preliminary study on the relationship between in vitro lactic acid bacteria, intestinal microecology and sepsis
CX Wei, JY Li, XZ Wang
Fujian Medical University Union Hospital, Department of Gastroenterology, Fuzhou, China
P281 The effects of vitamin D level on sepsis severity and risk of hospitalization in emergency patients
M Romposra1, K Trongtrakul2, A Vaniichkulbodee1
1Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Emergency Medicien, Bangkok, Thailand; 2Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Internal Medicine, Bangkok, Thailand
P282 A new and accurate low-cost printable pH sensor tested in a preclinical model for detecting changes in metabolic acidosis
Z Tehrani1, S Whelan1, M Lawrence2, S Pillai2, A Evans2, M Peacock3, D Gethin4, O Guy5
1Centre for Nano Health, College of Engineering, Swansea University,, Swansea, United Kingdom; 2Welsh Centre for Emergency Medicine Research Morriston Hospital Swansea Bay University Health Board, Swansea, United Kingdom; 3Zimmer and Peacock Ltd - 1 Market Hill, Royston, SG8 9JL, United Kingdom; 44Welsh Centre for Printing and coating, College of Engineering, Swansea University, Swansea SA18EN, United Kingdom; 5Department of Chemistry, College of Science, Swansea University, Swansea SA2 8PP, UK, United Kingdom
P283 Feasibility of new hand-held near-infrared spectroscopy (NIRS) monitor during prehospital anaesthesia
J Nurmi1, P Laukkanen-Nevala1, H Kirves2, L Raatiniemi3, M Tommila4, H Piiroinen5, P Karhivuori6, S Tukia7, T Toivonen1, A Olkinuora1
1FinnHEMS, Research and Development Unit, Vantaa, Finland; 2Helsinki University Hospital and Univeristy of Helsinki, Emergency Medicine and Services, FinnHEMS 10, Helsinki, Finland; 3Oulu University Hospital, Centre for Prehospital Emergency Care, Oulu, Finland; 4Turku University Hospital, Division of Perioperative Services, Intensive Care and Pain Medicine, Turku, Finland; 5Tampere University Hospital, Emergency Medical Services, Tampere, Finland; 6Kuopio University Hospital, Centre for Prehospital Emergency Care, Kuopio, Finland; 7Lapland hospital district, Lapland HEMS unit, Rovaniemi, Finland
P284 Risk-adjusted management strategies for patients admitted with acute pulmonary embolism to a teaching hospital in the UK
T Owen, N Bunker
Royal London Hospital, Critical Care Unit, London, United Kingdom
P285 Serum vitamin C levels were decreased from patients with severe emergency patients: an electron spin resonance study
R Takenaka1, S Matsumoto2, S Fujimoto1, T Himeno1, S Nureki3, K Ishii1, T Sakamoto4, O Shigemitsu1
1Oita University Hospital, Department of Emergency Medicine, Yufu city, Oita, Japan; 2Oita University Hospital, Department of Anaesthesiology and Intensive Care Medicine, Yufu city, Oita, Japan; 3Oita University Hospital, Department of Respiratory Medicine and Infectious Diseases, Yufu city, Oita, Japan; 4Oita University Hospital, Advanced Trauma, Emergency and Critical Care Center, Yufu city, Oita, Japan
P286 The revised national early warning score (NEWS) with modified Glasgow PROGNOSTIC SCORE (mGPS) is superior to the NEWS for predicting in-hospital mortality in elderly emergency patients
T Mitsunaga
Jikei university school of medicine, Emergency Medicine, Tokyo, Japan
P287 Combination of ECG and cardiovascular risks factors to increase the diagnostic performance of chest pain triage at emergency department. CECIDOC study, preliminary results
AS Pirot1, D Castanares Zapatero2, M Dechamps3
1Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Emergency Department, Brussels, Belgium; 2Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Intensive Care Unit, Brussels, Belgium; 3Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Cardiovascular Intensive Care Unit, Brussels, Belgium
P288 To scan or not to scan? Should we be performing CT head scans on obtunded patients admitted to intensive care with suspected self-poisoning
A Lee, R Hunt, P Margetts
University Hospital Plymouth Trust, Intensive Care Unit, Plymouth, United Kingdom
P289 Local audit of urinary catheterization practices in accordance with Northampton Healthcare NHS Foundation Trust guidelines 2015
MH Sultan
Lahore General Hospital, Lahore, Pakistan, Department of Internal Medicine, Lahore, Pakistan
P290 Metformin-associated lactic acidosis in ICU
M Mackovic, N Maric
Clinical hospital Sveti Duh, Zagreb, Croatia
P291 Epigenetic and morphological aspects of brain damage in acute exposure to clozapine combined with ethanol (experimental study)
A Goloubev1, A Babkina1, M Khadzhieva2, I Rhyzhkov2, A Kuzovlev2, A Bashirova3, D Sundukov3
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; Dept. of Forensic Medicine, Peoples’ Friendship University of Russia, Moscow, Russia; 2Federal research and clinical center of intensive care medicine and rehabilitology, Moscow, Russia; 3Department of Forensic Medicine, Peoples’ Friendship University of Russia, Moscow, Russia
P292 Prevalence, treatment and outcome of adder bites in South West Wales. Are current guidelines safe?
S Devine1, S Pillai2, J Whitley3, M Lawrence4, K Morris5, PA Evans3
1Welsh Centre for Emergency Medicine Research, Emergency Department, Swansea, United Kingdom; 2Welsh Centre for Emergency Medicine Research, Emergency Department/Intensive Care Unit, Swansea, United Kingdom; 3Welsh Centre for Emergency Medicine Research, Welsh Centre for Emergency Medicine Research, Swansea, United Kingdom; 4Swansea University, Swansea University, Swansea, United Kingdom; 5Cardiff Metropolitan University, Cardiff Metropolitan University, Cardiff, United Kingdom
P293 Cut-offs for increased risk of 7-day mortality, for vital- and laboratory values; have we got them right?
PB Pedersen1, DP Henriksen2, M Brabrand1, AT Lassen1
1Odense University Hospital, Department of Emergency Medicine, Odense C, Denmark; 2Odense University Hospital, Department of Clinical Biochemistry and Pharmacology, Odense C, Denmark
P294 The workload in the emergency room: direct assessment by the Therapeutic Intervention Scoring System-76 and indirect assessment by the NASA Task Load Index
NE Nouira1, L Arbi2, D Chtourou1, A Chamsi1, W Bahria1, EM Ben Othmane1, M Bouraoui1, M Ben Cheikh1
1Mongi Slim Academic Hospital, Emergency Department, Tunis, Tunisia; 2Ministry of Public Health, Directorate of Medical Inspection, 1029 Bab Saâdoun Tunis, Tunisia
P295 The role of simulation-based education in cardiovascular emergencies for medical students’ basic training
R Benmalek1, S Abouradi2, R Habbal2, M Mouhaoui3
1CHU Ibn Rochd, Cardiology Department, Casablanca, Morocco; 2Cardiology department, CHU Ibn Rochd, Casablanca, Cardiology, Casablanca, Morocco; 3SAMU Urgences 02, Samu urgences 02, Casablanca, Morocco
P296 Great East Japan Earthquake and Tsunami supressed family- and friend-performance of cardiopulmonary resuscitation
H Inaba1, K Takada2, H Kurosaki2, Y Wato3, A Yamashita2
1Kanazawa University Graduate School of Medicine, Department of Circulatory Emergency and Emergency Medical Science, Kanazawa, Japan; 2Kanazawa University Graduate School of Medicine, Kanazawa, Japan; 3Kanazawa Medical University, Uchinada, Japan
P297 Prognostic value of ISS and TRISS scores in terrorism victims
C Romdhani1, T Khoufi2, M Shimi3, W Sellami4, A Mrabet2, M Ferjani2
1Military Hospital of Gabes, Anesthesiology & Intensive care, Gabes, Tunisia; 2Ministry of Defense, Directorate General of Military Health Tunisian Armed Forces, Tunis, Tunisia; 3Military Hospital of Tunis, Department of Forensic Medicine, Tunis, Tunisia, 4Military Hospital of Tunis, Departement of Anesthesiology & Intensive Care, Tunis, Tunisia
P298 Mega-disaster medicine, including NBC hazards and intensivist
Y Haraguchi1, Y Tomoyasu2, T Tsubata2, M Hoshino3, M Sakai2, T Ishihara2, E Hoshino2
12 chome Matsue Edogawaku ward, Keiyo Hospital, Tokyo, Japan; 22 chome Matsue Edogawaku ward, Disaster Medicine Compendium Group, Tokyo, Japan; 32 chome Matsue Edogawaku ward, Disaster Medicine Compendium Group, Keiyo Hospital, Tokyo, Japan
P299 Repair of the bodily injury to those injured by terrorism in Tunisia (2013-2019)
M Gabouj
Ministère de la défense Nationale Tunisienne, Centre de réforme, Tunis, Tunisia
-
Our 177 wounded were male, 96% of whom belonged to the army.
-
The average age was 36 years and 3 months ± 8.869.
-
Half of our wounded were troopers.
-
Infantry and special forces were the most exposed military units.
-
Half of the accidents were recorded in the Kasserine region (88 cases).
-
Chronic post-traumatic stress disorder (CPTSS) was found in 130 injured, followed by amputations in 18 injured.
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The after-effects were psychological in 32%, physical in 26% and mixed in 39% of our injured.
-
The PPI rate ranged from 36% to 75% in 23.7% of injuries..
-
More than half of the injured had returned to their professional activity, 33% were put on reform for health reasons.
P300 Questionnaire survey on prevalence of rapid response systems in acute-care hospitals in western Japan
J Ishii1, H Kamada2, K Hosokawa1, S Yamaga1, K Ota1, N Shime1
1Hiroshima University Hospital, Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan; 2Hiroshima University Hospital, Medical student, Department of Medicine, Hiroshima, Japan
P301 Higher rapid response system call rate was associated with decreased short-term serious outcome: Japanese nationwide database retrospective study
T Kurita1, TA Nakada2, R Kawaguchi2, S Fujitani3, K Atagi4, T Naito3, M Arai5, H Arimoto6, T Masuyama7, S Oda1
1Chiba University Graduate School of Medicine, Department of Emergency and Critical Care Medicine, Chiba, Japan; 2Chiba University Graduate School of Medicine, Chiba University Graduate School of Medicine, Department of Emergency and Critical Care Medicine, Chiba, Japan; 3St. Marianna University School of Medicine, Department of Emergency and Critical Care Medicine, Kanagawa, Japan; 4Nara General Medical Center, Intensive Care Unit, Nara, Japan; 5Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Division of Advanced Surgical Oncology, Kanagawa, Japan; 6Osaka City General Hospital, Department of Emergency and Critical Care Medical Center, Osaka, Japan; 7Jichi Medical University Saitama Medical Center, Department of Emergency and Critical Care Medicine, Saitama, Japan
P302 Time from rapid response team activation to ICU admission
J Camões1, R Guedes2, S Gaião3, R Pimentel2, R Roncon-Albuquerque Jr4, JA Paiva3
1ULS Matosinhos, Department of Emergency and Intensive Care Medicine, Matosinhos, Portugal; 2São João Hospital Center, Department of Emergency and Intensive Care Medicine, Porto, Portugal; 3São João Hospital Center | Faculty of Medicine - University of Porto, Department of Emergency and Intensive Care Medicine| Department of Medicine, Porto, Portugal; 4São João Hospital Center | Faculty of Medicine - University of Porto, Department of Emergency and Intensive Care Medicine | Department of Surgery and Physiology, Porto, Portugal
P303
P304 Blood and blood products use in intensive care unit
M Akcivan, S Bozbay, O Demirkiran
Istanbul University Cerrahpasa, Anesthesiology and Intensive Care, Istanbul, Turkey
P305 Association between anemia or red blood cell transfusion and outcome in oncologic surgical patients. A retrospective observational study
X Chapalain1, Y Ozier1, C Le Niger2, O Huet1, C Aubron3
1Brest University Hospital, Department of Anaesthesiology and Surgical Intensive Care., Brest, France; 2Brest University Hospital, Hemovigilance Unit, Brest, France; 3Brest University Hospital, Medical Intensive Care Unit, Brest, France
P306 Transfusion impaired skin blood flow when initially high
E Cavalcante dos santos, W Mongkolpun, P Bakos, AL Alves da Cunha, C Woitexen Campos, JL Vincent, J Creteur, FS Taccone
Erasme Hospital, Intensive Care Department, Brussels, Belgium
P307 Effects of erythrocyte transfusion on hemodynamic and oxygen metabolism: cross-sectional study of paired series
A Trifi1, A Mehdi2, H Fazzeni2, F Daly2, Y Touil2, S Abdellatif2, S Ben Lakhal2
1La Rabta hopital, Medical intensive care unit., Tunis, Tunisia; 2La Rabta hopital, Tunis, Tunisia
P308 Local audit of blood transfusion practices in comparison with NICE blood transfusion guidelines 2015
MH Sultan
Lahore General Hospital, Lahore, Pakistan, Department of Internal Medicine, Lahore, Pakistan
P309 A systematic review and meta-analysis exploring the safety and efficacy of erythropoiesis- stimulating agents in critically ill patients
E Litton1, P Latham2, J Inman3, J Luo4, P Allan5
1SJOG Hospital Subiaco, ICU, Perth, Australia; 2Noosa hospital, ICU, Sunshine Coast, Australia; 3Fiona Stanley Hospital, Anaesthesia, Murdoch, Australia; 4Rockingham General Hospital, Anaesthetics, Rockingham, Australia, 5Fiona Stanley Hospital, ICU, Murdoch, Australia
P310 Safety and efficacy of prothrombin complex concentrate in PPH
A Ronenson1, E Shifman2, A Kulikov3
1Tver Regional Perinatal Center, Anesthesia and Intensive care, Tver, Russia; 2Moscow Regional Research Clinical Institute named M.F. Vladimirsky, Anesthesia and Intensive care, Moscow, Russia; 3Ural State Medical University, Anesthesia and Intensive care, Yekaterinburg, Russia
P311 The effect of intravenously given vitamin K1 to critically ill patients with spontaneously increased prothrombin time
S Dahlberg1, U Schött1, T Kander2
1Skåne University Hospital, Lund, Sweden; 2Skåne University Hospital, Anaesthesia and Intensive Care, Lund, Sweden
P312 Comparison of coagulation parameters associated with fibrinogen concentrate and cryoprecipitate in the treatment of bleeding in pseudomyxoma peritonei surgery: results from the prospective, randomized, controlled phase 2 FORMA-05 study
A Roy1, N Sargant1, S Rangarajan1, S Alves1, J Bell1, S Stanford1, C Solomon2, I Kruzhkova3, S Knaub2, F Mohamed1
1Basingstoke and North Hampshire Hospital, Hampshire, United Kingdom; 2Octapharma, Lachen, Switzerland; 3Octapharma, Clinical R&D, Lachen, Switzerland
Parameter | Endogenous thrombin potential (nmol/L/min) | Endogenous thrombin potential (nmol/L/min) | Plasma fibrinogen concentration (g/L) | Plasma fibrinogen concentration (g/L) |
---|---|---|---|---|
Treatment group | HFC | Cryoprecipitate | HFC | Cryprecipitate |
Baseline mean | 1514.5 (430.6) | 1639.1 (339.1) | 4.79 (1.316) | 4.50 (1.497) |
Interoperative, 2hr after surgery start, mean (SD) | 1673.5 (340.1) | 1690.2 (320.2) | 3.20 (0.722) | 2.67 (0.984) |
Interoperative, 6hr after surgery start, mean (SD) | 1310.7 (171.2) | 1260.7 (342.2) | 2.34 (0.610) | 1.91 (0.543) |
Postoperative end-of-surgery, mean (SD) | 1225.4 (220.7) | 1346.4 (243.6) | 2.21 (0.515) | 2.08 (0.562) |
2 days after surgery end, mean (SD) | 1263.44 (176.9) | 1385.6 (301.6) | 5.47 (0.832) | 5.24 (0.818) |
10 days after surgery end, mean (SD) | 1426.16 (260.4) | 1357.0 (349.5) | 6.62 (1.484) | 6.48 (1.685) |
P313 Estimation of fibrinogen deficit based on base excess and lactate level at the patient with multiple trauma
A Baetu, IC Grintescu, C Cobilinschi, M Tiglis, AM Cotae, M Buiuc, E Ciobanu, IM Grintescu
Emergency Clinical Hospital Bucharest, Anesthesia and Intensive Care Unit, Bucharest, Romania
P314 Fibrinogen-based vs plasma-based therapy for trauma-induced coagulopathy: implications on blood transfusion
GN Jesus1, S Cunha2, L Carneiro3, J Galacho3, SM Fernandes1
1Centro Hospitalar Universitário Lisboa Norte, Serviço de Medicina Intensiva, Lisboa, Portugal; 2Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal; 3Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal
P315 Prospective, multicenter, randomized study comparing administration of clotting factor concentrates with a standard massive hemorrhage protocol in severely bleeding trauma patients
L Da Luz1, J Callum2, A Beckett3, H Peng4, P Engels5, N Parry6, H Tien1, A Nathens7, B Schwartz8, K Karkouti9
12075 Bayview Avenue, Dept of Surgery, Toronto, Canada; 22075 Bayview Avenue, Transfusion Medicine, Toronto, Canada; 3Saint Mchael`s Hospital, Dept of Surgery, Toronto, Canada; 4Defence Research and Development Canada, Toronto Research Center, Defence Research and Development Canada, Toronto Research Center, Toronto, Canada; 5Hamilton General Hospital, Dept of Surgery, Hamilton, Canada; 6London Health Sciences Centre, Dept of Surgery, London, Canada; 72075 Bayview Avenue, Toronto, Canada; 8Clinical Research & Development, Octapharma, Clinical Research & Development, Octapharma, Hoboken, USA, Hoboken, United States; 9University Health Network, Sinai Health System, and Women’s College Hospital, Dept of Anesthesia and Pain Management, Toronto, Canada
P316 Trauma-induced coagulopathy detected by the Quantra® QStat® system
E Michelson1, M Cripps2, B Ray3, D Winegar4, F Viola5
1Texas Tech University Health Sciences Center El Paso, Department of Emergency Medicine, El Paso, United States; 2University of Texas Southwestern, Surgery, Dallas, United States; 3University Medical Center of El Paso, Patient Blood Management, El Paso, United States; 4HemoSonics, LLC, Clinical Affairs, Charlottesville, United States; 5HemoSonics, LLC, Chief Scientific Officer, Charlottesville, United States
P317 First real-world experiences with a new human fibrinogen (FIBRYGA®) in France based on temporary authorization
F Stéphan1, L Gutermann2, M Pennetier3, S Bourget4, S Djabarouti5, J Berdugo6, Y Fardini7, P Clerson7, C Belmokhtar8, G Hébert2
1Hôpital Marie Lannelongue, Unité de soin intensif, Le Plessis Robinson, France; 2Hôpital Marie Lannelongue, Service Pharmacie et Stérilisation, Le Plessis Robinson, France; 3Hôtel Dieu, Pharmacie Clinique, Nantes, France; 4Centre Hospitalier de Valence, Service Pharmacie, Valence, France; 5Groupe Hospitalier Sud, CHU de Bordeaux, Service Pharmacie, Pessac, France; 6Hôpital Saint-Joseph, Service Pharmacie, Marseille, France; 7Soladis Clinical Studies, Roubaix, France, 8Octapharma France, Boulogne-Billancourt, France
P318 Functional testing for tranexamic acid effect duration using modified viscoelastometry
T Kammerer1, P Groene2, S Sappel2, P Scheiermann2, ST Schaefer2
1Ruhr-University Bochum, Institute of Anaesthesiology, Heart and Diabetes Center NRW, Bad Oeynhausen, Germany; 2Ludwig-Maximilans University, Department of Anaesthesiology, Munich, Germany
P319 Fibrinogen concentrate and ROTEM-guided hemostasis management are associated with less bleeding and transfusion in surgery for thoracic aortic dissection
M Stefan, I Marinica, A Paunescu, M Luchian, A Stegaru, A Dumitrescu, D Filipescu
"Prof Dr CC Iliescu" Emergency Institute for Cardiovascular Diseases, ICU II, Bucuresti, Romania
Fibrinogen group (n= 41) | Control group (n= 19) | p-value | |
PRBCs - patients transfused (n, %) | 35 (85,4%) | 18 (94,7%) | |
PRBCs - units per patient (median, IQR) | 4 (1-6) | 5 (3-10) | 0,07 |
FFP - patients transfused (n, %) | 28 (68,3%) | 19 (100%) | |
FFP - units per patient (median, IQR) | 4 (0-6) | 9 (4-18) | 0,001 |
Cryoprecipitate - units per patient (median, IQR) | 0 | 6 (0-10) | <0,001 |
Chest tube drainage (ml/24h, median, IQR) | 640 (450-1075) | 1037 (800-1600) | 0,009 |
Surgical re-exploration (n, %) | 2 (4,9%) | 6 (31,6%) | 0,005 |
P320 IFiTEM a novel modality of visco-elastic blood clotting test for ROTEM device
J Benes1, M Peltanova2, J Zatloukal2
1Faculty of Medicne in Plzen, Department of Anesthesiology and Intensive Care Medicine, Plzen, Czech Republic; 2Faculty of Medicne in Plzen, Plzen, Czech Republic
P321 Factor Xa inhibitor antidote, andexanet alfa differentially reverses the effects of apixaban, betrixaban, edoxaban and rivaroxaban
F Siddiqui1, D Hoppensteadt1, W Jeske1, A Tafur2, K Zorriasateyn2, E Ramacciotti3, E Bontekoe1, J Fareed1
1Loyola University Medical Center, Pathology, Maywood, United States; 2North Shore University Health System, Cardiovascular Institute, Skokie, United States; 3Santa Casa School of Medicine, Cardiovascular Institute, São Paulo, Brazil
P322 Correlation between central laboratory and point of care measurements of INR in adult intensive care patients
D Ernest1, D Bhatia2, A Pakavakis1
1Monash Health & Monash University, Intensive Care Unit, Melbourne, Australia; 2Monash Health, Critical Care and Perioperative Medicine, Melbourne, Australia
P323 MA/R predicts sepsis induced coagulopathy and mortality: a prospective observational study
X Li
Fist affiliated Hospital of China Medical University, ICU, Shenyang, China
P324 The hemostatic effect and quantification of arterial and venous blood sampling on clot microstructure in sepsis patients: Assessment of a functional biomarker
S Pillai1, G Davies2, M Lawrence2, J Whitley2, PR Williams3, K Morris4, PA Evans2
1Welsh Centre for Emergrency Medicine Research, Emergency Department, Swansea, United Kingdom; 2Welsh Centre for Emergrency Medicine Research, Swansea, United Kingdom; 3Swansea University, Swansea, SA2 8PP, United Kingdom; 4Cardiff Metropolitan University, Cardiff- CF5 2YB, United Kingdom
P325 The effect of recalcification of citrated blood on clot microstructure using a new biomarker of clot quality
BL Selwyn1, M Lawrence2, PR Williams3, K Hawkins4, D Curtis4, K Morris5, PA Evans1
1Welsh Center of Emergency Medicine, Swansea, United Kingdom; 2Welsh Center of Emergency Medicine, HBRU, Swansea, United Kingdom; 3Swansea University, School of Engineering, Swansea, United Kingdom; 4Swansea University, Swansea, United Kingdom; 5Cardiff Metropolitan University, Cardiff, United Kingdom
P326 Thromboelastography in Dengue fever in emergency department (TiDE)
MS Roslanuddin1, H Rossman2, FJ Sabariah2
1Hospital Raja Permaisuri Bainun,Ipoh, Emergency Department, Ipoh, Perak, Malaysia; 2Hospital Sungai Buloh, Emergency Department, Selangor, Malaysia
P327 Agreement between the thromboelastography reaction time parameter using fresh and citrated whole blood during extracorporeal membrane oxygenation with TEG®5000 and TEG®6s
M Panigada, S De Falco, N Bottino, P Properzi, G Grasselli, A Pesenti
Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico, Intensive Care Unit, Milano, Italy
P328 Pharmacist-initiated protocol for antiXa-based enoxaparin dosing in trauma patients
EN Morales1, CJ Richardson2, JT Jancik1
1Hennepin County Medical Center, Pharmacy, Minneapolis, United States; 2Hennepin County Medical Center, Surgery, Minneapolis, United States
All Patients (N = 375) | BMI < 40 kg/m2 (n = 337) | BMI > 40 kg/m2 (n = 38) | |
---|---|---|---|
Time to goal antiXa in days – median (IQR) | 3 (2-6) | 3 (2-5.8) | 2.5 (1.8-8) |
AntiXa within goal at first check | 168/375 (44.8%) | 153/337 (45.4%) | 13/38 (34.2%) |
Final dose (mg) to reach goal antiXa–mean +/- SD | 34.5 +/- 8.0 | 33.2 +/- 5.9 | 46.5 +/- 13.5 |
Number of dose changes – mean +/- SD | 0.35 +/- 0.6 | 0.33 +/- 0.55 | 0.64 +/- 0.93 |
Rates of VTE | 8/375 (2.1%) | 7/337 (2.1%) | 1/38 (2.6%) |
Rates of bleeding | 0/375 (0.0%) | 0/337 (0.0%) | 0/38 (0.0%) |
P329 Anti factor Xa (AFXa) activity monitoring in a mixed ICU patient population – are we giving enough enoxaparin to our patients?
TM Mann1, O Rahlin2, I Barnet1, M Izak2, AH Mayo1
1Assuta Medical Center, Department of Intensive Care, Ashdod, Israel; 2Assuta Medical Center, Department of Hematology, Ashdod, Israel
P330 Gel point analysis quantifies the anticoagulant effect of rivaroxaban in first time DVT
VJ Evans1, MJ Lawrence1, J Whitley1, C Johns2, SK Pillai1, PR Williams3, K Hawkins4, K Power5, K Morris6, PA Evans1
1Welsh Centre for Emergency Medicine Research, Swansea, United Kingdom; 2Singleton Hospital, Acute GP Unit, Swansea, United Kingdom; 3Swansea University, College of Engineering, Swansea, United Kingdom; 4Swansea University, Medical School, Swansea, United Kingdom; 5Singleton Hospital, Pharmacy, Swansea, United Kingdom, 6Cardiff Metropolitan University, Cardiff School of Sport and Health Sciences, Cardiff, United Kingdom
DVT baseline | Rivaroxaban 15mg BD dose | Rivaroxaban 20mg OD dose | Significance valve | |
---|---|---|---|---|
TGP (s) | 267.0 ± 63.3 | 392.3 ± 135.7 | 395.5 ± 194.2 | <0.001 |
Prothrombin Time (s) | 10.8 ± 0.58 | 13.6 ± 1.73 | 12.6 ± 1.47 | <0.001 |
P331 Impact of protocoled nursing care on quality performance measures in patients with severe trauma
N Matsumoto1, M Sato1, M Toyodome1, Y Shimoikeda1, T Sawai1, M Murai1, J Yoshimura2, K Yamakawa2, S Fujimi2
1Osaka General Medical Center, Department Of Nursing, Osaka, Japan; 2Osaka General Medical Center, Division of Trauma and Surgical Critical Care, Osaka, Japan
P332 Long-term physical function and quality of life in patients with unstable pelvic ring fractures
N Saito1, T Seo2, H Iida2, H Matsumoto2
1Nippon Medical School Chiba Hokusoh Hospital, Shock and Trauma Center, Inzai, Chiba, Pref, Japan; 2Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Pref, Japan
P333 Electrochemically induced change in the morphology of red blood cells – a new method for the diagnosis of critical conditions
A Evseev1, I Goroncharovskaya1, A Kuzovlev2, K Popugaev1, S Petrikov1
1N.V. Sklifosofsky research institute of emergency medicine, Moscow, Russia; 2Federal research and clinical center of intensive care medicine and rehabilitology, Moscow, Russia
P334 Deep neural network models for detection of severe trauma injuries using whole-body CT scout
N Okada1, K Yamakawa1, S Inoue2, Y Umemura1, J Yoshimura1, Y Matsuzawa3, S Fujimi1
1Osaka General Medical Center, Division of Trauma and Surgical Critical Care, Osaka, Japan; 2AI study group in the emergency room, Image analysis group, Tokyo, Japan; 3Brown University, Department of Mathematics, Rhode Island, United States
P335 Launch of clinical information system in intensive care unit – facilitating staff in transition from paper records to electronic database
YC Wong, YL Lau, WT Yeung, PO Lei, KC Law, MC Cheung
Ruttonjee & Tang Shiu Kin Hospitals, Cardiac & Intensive Care Unit, Hong Kong SAR, Hong Kong
P336 Reducing unnecessary laboratory testing in an intensive care unit of a tertiary hospital - what changed after one year?
L Simvoulidis1, RC Costa2, CA Ávila2, TS Sória2, MM Menezes2, JR Rangel2, JP Pinho2, RP Pereira2, AP Porto2
1Hospital Unimed Rio, UTI Geral, Rio De Janeiro, Brazil; 2Hospital Unimed Rio, UTI Geral, Rio De Janeiro, Brazil
P337 Evaluating the medication reconciliation errors in 2 ICUs after implementing a hospital-wide integrated electronic health record system
A Rosillette, R Shulman, Y Jani
University College Hospital, Centre for Medicines Optimisation Research and Education, London, United Kingdom
Drug class | Drug class initiated in ICU | Drug class continued after transfer to the ward | Drug class continued on home discharge |
---|---|---|---|
Antibiotics | 22 | 16 (72.7%) | 9 (40.9%) |
Steroids | 10 | 8 (80.0%) | 4 (40.0%) |
Analgesics | 19 | 17 (89.5%) | 11 (57.9%) |
Insomnia | 7 | 6 (85.7%) | 1 (14.3%) |
Anticoagulants | 2 | 2 (100.0%) | 2 (100.0%) |
Antipsychotics | 4 | 2 (50.0%) | 0 (0.0%) |
Gastroprotective drugs | 23 | 22 (95.6%) | 12 (52.1%) |
P338 Sepsis bundle delivery and intensive care outcomes
D Cottam, M Zuleika, F Wade-Smith, W Gray
Royal Surrey County Hospital, Intensive Care Unit, Guildford, United Kingdom
P339 Compliance with 3-6h sepsis resuscitation bundle of surviving sepsis campaign in an emergency department
MH Hagui1, RA Allani2, OD Djebbi1, Ml Ben Lassoued1, Kl Lamine1
1Main Military Hospital of Tunis, Emergency departement, Montfleury, Tunisia; 2Main Military Hospital of Tunis, General Directorate of Military Health, Montfleury, Tunisia
P340 Patterns and outcome of critical care admissions with sepsis in a resource limited setting
M Edirisooriya Maddumage1, Y Gunasekara2, D Priyankara1
1National Hospital of Sri Lanka, Medical Intensive Care Unit, Colombo 10, Sri Lanka; 2Sri Jayawardenepura General Hospital, Department of Critical Care, Nugegoda, Sri Lanka
P341 Improving the safe use of nasogastric tubes in the ICU: from computer to classroom
A Chapman1, M Perera2, M Perera2, P Beddoes3, DJ Melia4
1Lister Hospital, Department of Anaesthesia, Hertfordshire, United Kingdom; 2Eastbourne Hospital, East Sussex, United Kingdom; 3Whipps Cross University Hospital, Department of Anaesthesia & Critical Care, London, United Kingdom; 4Whipps Cross University Hospital, Dept of Anaesthesia and Critical Care, London, United Kingdom
P342 A systematic review of anticoagulation strategies for patients with atrial fibrillation in critical care
A Nelson, B Johnston, A Waite, I Welters, G Lemma
University of Liverpool, Liverpool, United Kingdom
P343 A review of handovers on the intensive care unit
EJ Jones1, DH Hepburn2
1Cardiff University, Medical School, Cardiff, United Kingdom; 2Royal Gwent Hospital, Intensive Care Medicine, Newport, United Kingdom
P344 Caregiver burden after prolonged cardiothoracic critical care
P Henderson1, I Quasim2, A Asher3, L Campbell3, M Shaw4, T Quasim5, J McPeake5
1University of Glasgow, Department of Anaesthesia and Intensive Care medicine, Glasgow, United Kingdom; 2Golden Jubilee National Hospital, Cardiothoracic Anaesthesia and Critical Care, Glasgow, United Kingdom; 3Golden Jubilee National Hospital, Cardiothoracic Critical Care, Glasgow, United Kingdom; 4NHS Greater Glasgow & Clyde, Department of Clinical Physics and Bioengineering, Glasgow, United Kingdom; 5University of Glasgow, Department of Anaesthesia and Intensive Care Medicine, Glasgow, United Kingdom
P345 Evaluation of burnout in a Brazilian intensive care center
E Perecmanis
Hospital Caxias Dor, Intensive Care, Duque de Caxias, Brazil
P346 Depression and burnout in the ICU: an urban perspective of prevalence and trend
I Greaves1, R Maharaj2
1King College Hospital, Critical Care, London, United Kingdom; 2King College Hospital, London, United Kingdom
P347
P348 Analysis of clinical pharmacists’ contributions in an intensive care unit after implementing an hospital-wide fully integrated electronic health record system
A Rosillette, R Shulman, Y Jani
University College Hospital, Centre for Medicines Optimisation Research and Education, London, United Kingdom
Type of contribution | Medication error | Optimization | Consult | Total |
---|---|---|---|---|
Period 1 | 21 | 26 | 0 | 47 |
Period 2 | 12 | 12 | 1 | 25 |
Period 3 | 17 | 21 | 0 | 38 |
Period 4 | 16 | 34 | 0 | 50 |
Total | 66 | 93 | 1 | 160 |
P349 Evaluation of noise level in intensive care unit
L Karabýyýk, BS Kalýn, M Çimen, Ö Nadastepe
Gazi University School of Medicine, Anesthesiology and Intensive Care, Ankara, Turkey
P350 Clinical profile and outcomes after admission in a tertiary level critical care facility in a low income country
E Shimber
Hawassa University Comprehensive Specialized Hospital, Emergency and Critical Care Medicine, Hawassa, Ethiopia
P351 Early mortality in critically ill patients admitted to ICU
A Estella, M Gracia Romero, M Recuerda Nuñez
University Hospital of Jerez, Intensive & Critical Care, Cadiz, Spain
Dead first 48 hours. n: 72 | Dead after 48 hours . n: 66 | |
---|---|---|
Age | 65.16±16.7 | 66.01±10.8 |
Charlson Index | 4.1±2.28 | 4.8±2.19 |
Apache II | 27.31±7.84 | 19.98±7.66 |
Gender (% male) | 59.7% | 74.2% |
Origin: Medical ward Surgical ward | 26.4% 12.5% 48.6% 8.3% | 34.8% 15.2% 33.3% 16.7% |
Most frequent admission diagnosis | Septic shock 16.7% Stroke 16.7% Cardiac arrest15% | Septic shock 25.8% Stroke 19.7% Surgery 15.2% |
Limitation support therapies | 19.4% | 37.9% |
P352 Are you ready? - an audit of the 2018 guidelines in maternal critical care in a major obstetric centre
M Smith1, Y Metodiev2, H Lynes3, D O´Neil3
1Department of Anaesthetics and Intensive Care, Anaesthetics/ICU, Leicester, United Kingdom; 2Department of Anaesthetics and Intensive Care, Department of Anaesthetics, Leicester, United Kingdom; 3Department of Anaesthetics and Intensive Care, Leicester, United Kingdom
P353 Communication, interprofessional co-operation of ICU staff, and professional satisfaction
T Bekiarii1, D Papadopoulos2, A Georgakis3, P Papamichalis2, P Katsiafylloudis2, E Neou2, M Chatzimichail2, A Palioura2, M Malliarou4, A Komnos2
1Prefecture Of Thessaly, Department Of Public Health, Larisa, Greece; 2General Hospital Of Larisa, Intensive Care Unit, Larisa, Greece; 3Prefecture Of Thesssaly, Statistician/Mathematician, Larisa, Greece; 4University Of Thessaly, Nursing School/ Health Sciences, Larisa, Greece
P354 Longitudinal trends in intensive care admission according to age in Wales: 2008-2017
R Pugh1, M Al Sallakh2, A Akbari2, R Bailey2, R Griffiths2, C Subbe3, C Thorpe4, C Battle2, T Szakmany5, R Lyons2
1Department of Anaesthetics, Glan Clwyd Hospital, Bodelwyddan, United Kingdom; 2Swansea University, Swansea, United Kingdom; 3Bangor University, Bangor, United Kingdom, 4Ysbyty Gwynedd, Bangor, United Kingdom; 5Cardiff University, Cardiff, United Kingdom
Age (years) | 18-64 | 65-79 | 80+ |
Episodes | 39,551 (46.2%) | 32,928 (38.5%) | 13,150 (15.4%) |
Female | 47.1% | 42.9% | 49.5% |
Moderate-severe comorbidity | 76.1% | 93.4% | 94.5% |
Frailty (moderate-severe eFI) | 8.7% | 23.7% | 36.5% |
Invasive ventilation | 44.9% | 38.1% | 31.2% |
Hospital mortality | 14.5% | 25.0% | 33.5% |
1-year mortaility | 25.7% | 45.9% | 62.7% |
P355 ICU discharge into weekends and public holidays: an observational study of mortality
N Mawhood, T Campbell, S Hollis-Smith, K Rooney
Bristol Royal Infirmary, General Intensive Care Unit, Bristol, United Kingdom
P356 Follow-up of psycho-emotional effects of organ procurement: difficult to study family members opposed to organ donation
G Piemonte1, L Cecci1, C Di Pasquale2, L Quarta2, L Rasero1, M Bombardi3, C Guetti4, ML Migliaccio3, A Peris5
1University of Florence, Department of Health Science, Florence, Italy; 2University of Pisa, Department of Culture and Forms of Knowledge, Pisa, Italy; 3Careggi Teaching Hospital, Regional Centre for Organ and Tissue Allocation, Florence, Italy; 4Careggi Teaching Hospital, Intensive Care Unit and Regional ECMO Referral Center, Florence, Italy; 5Tuscany Region, Tuscany Transplant Authority, Florence, Italy
P357 Exploring psycho-emotional effects of organ procurement on potential donors’ relatives: preliminary results
L Cecci1, G Piemonte1, L Rasero1, A Giustini2, M Bombardi3, C Di Pasquale4, L Quarta4, ML Migliaccio3, A Peris5
1University of Florence, Department of Health Science, Florence, Italy; 2Careggi Teaching Hospital, Organ and Tissue Procurement Service, Florence, Italy; 3Careggi Teaching Hospital, Regional Centre for Organ and Tissue Allocation, Florence, Italy; 4University of Pisa, Department of Culture and Forms of Knowledge, Pisa, Italy; 5Tuscany Region, Tuscany Transplant Authority, Florence, Italy
P358 ICU readmission in adult Egyptian patients undergoing living donor liver transplant: incidence,causes and outcomes: A single centre retrospective observational study
HA Elgendy1, GM Elewa1, AA Korraa1, HA Ahmed1, MA El-metini2, MM Ahmed2, IM Montasser3, HM Dabbous3, MM Salah Eldin3, MF Abdelgafar2
1Faculty of Medicine Ain Shams University, Anesthesia and Intensive Care, Cairo, Egypt; 2Faculty of Medicine Ain Shams University, General Surgery, Cairo, Egypt; 3Faculty of Medicine Ain Shams University, Tropical Medicine, Cairo, Egypt
P359 Excellent results in kidney transplantation from donors with multiple organ failure - an unused resource in times of organ shortage
LJ Lehner1, M Dürr1, K Budde1, J Kruse1, D Zickler1, F Friedersdorff2, R Öllinger3, F Halleck1, D Khadzhynov1
1Charité Universitätsmedizin Berlin, Dept. of Nephrology and Medical Intensive Care, Berlin, Germany; 2Charité Universitätsmedizin Berlin, Dept. of Urology, Berlin, Germany; 3Charité Universitätsmedizin Berlin, Dept. of Surgery, Berlin, Germany
P360 Apheresis or not apheresis in controlled liver donation after circulatory death: a single centre experience in Italy
C Dallai1, S Baroni2, A Marudi2, S Ghedini1, M Talamonti1, S Rinaldi2, G Melegari2, E Bertellini2
1Università degli Studi di Modena e Reggio Emilia, Anestesia, Rianimazione e Terapia Intensiva e del dolore, Modena, Italy; 2Azienda Ospedaliero-Universitaria di Modena, Departement of Anesthesia and Intensive Care, Modena, Italy
P361 Gene expression profiles predict the likelihood of mortality in patients with postsurgical shock
P Martínez-paz1, M Aragón-Camino2, A Fadrique-Fuentes3, M Heredia-Rodríguez4, E Gómez-Sánchez2, M Lorenzo-López2, E Gómez-Pesquera2, H Gonzalo-Benito5, E García-Morán6, E Tamayo1
1Faculty of Medicine. University of Valladolid, Department of Surgery, Valladolid, Spain; 2Clinic University Hospital of Valladolid, Anesthesiology and Reanimation Service. Clinic University Hospital of Valladolid, Valladolid, Spain; 3Hospital of Medina del Campo, Anesthesiology and Reanimation Sevice, Hospital of Medina del Campo, Medina del Campo, Spain; 4University Hospital of Salamanca, Anesthesiology and Reanimation Service. University Hospital of Salamanca, Salamanca, Spain; 5Instituto de Estudios en Ciencias de la Salud de Castilla y León, Instituto de Estudios en Ciencias de la Salud de Castilla y León, Valladolid, Spain; 6Clinic University Hospital of Valladolid, Cardiology Service, Valladolid, Spain
P362 The prognostic ability of frailty and comorbid illness severity scores in septic shock
M Chotalia, M Bangash, T Matthews, D Parekh, J Patel
University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom
90-day mortality of medical condition | 90-day mortality of the remaining cohort | Relative risk (+95% CI) | |
---|---|---|---|
Hematological malignancy | 66% (54/81) | 40% (309/765) | 1.51 (1.28-1.80); p<0.0001 |
Solid organ cancer | 49% (105/213) | 41% (258/633) | 1.21 (1.03-1.42); p=0.04 |
Metastatic solid organ cancer | 60% (34/58) | 42% (329/788) | 1.40 (1.11-1.77); p=0.02 |
End stage renal disease | 52% (56/107) | 42% (307/739) | 1.26 (1.03-1.54); p=0.045 |
Chronic obstructive pulmonary disease | 54% (45/83) | 42% (318/763) | 1.3 (1.05-1.61); p=0.04 |
No comorbidities | 11% (6/53) | 45% (357/793) | 0.25 (0.12-0.54); p<0.0001 |
Age >80 | 60% (51/85) | 41% (312/761) | 1.46 (1.20-1.78); p=0.001 |
P363 Two years follow up of 196 interstitial lung diseases patients after intensive care unit stay
Y Tandjaoui-lambiotte1, F Gonzalez1, M Boubaya2, J Oziel1, G Van Der Meersch1, P Karoubi1, Y Uzunhan3, S Gaudry1, H Nunes3, Y Cohen1
1Avicenne Hospital, Intensive Care Unit, Bobigny, France; 2Avicenne Hospital, Statistics Department, Bobigny, France; 3Avicenne Hospital, Pulmunology, Bobigny, France
P364 Acute gastrointestinal injury (AGI) as a predictor of malnutrition and 1-year mortality in intensive care unit (ICU). A retrospective single center study
A Kasti1, M Nikolaki2, K Katsas2, F Solakis2, S Fotiou2, K Triantafylou3, AE Zouridaki4, S Patsilinakou5, A Armaganidis5, M Theodorakopoulou6
1Department of Nutrition and Dietetics, Attikon University Hospital, 1. Department of Nutrition and Dietetics, Attikon University Hospital, Athens, Greece; 2Department of Nutrition and Dietetics, Attikon University Hospital, Athens, Greece; 32nd Department of Internal Medicine, Hepatogastroenterology Unit, Attikon University Hospital, 2nd Department of Internal Medicine, Hepatogastroenterology Unit, Attikon University Hospital, Athens, Greece; 4Department of Human biology and Health Science University of Toronto, Toronto, Canada; 52nd ICU Department, Attikon University Hospital, Athens, Greece; 62nd ICU Department, Attikon University Hospital, Intensive Care Medicine, Athens, Greece
AGI Grade I(N-172) | AGI Grade II(N=28) | p | |
Age | 65(51-75) | 70(57-79) | 0.11 |
Male Gender(%) | 59 | 50 | 0.35 |
Malnutrition Risk(%) | 53 | 75 | 0.03 |
BMI (kg/m2) | 26.4(23.5-29.9) | 24.9(22.4-31) | 0.70 |
Patients achieved energy goal (%) | 39 | 39 | 0.90 |
1-year mortality (%) | 29 | 41 | 0.3 |
P365 The effect of ICU admission on frailty and activities of daily living at 6-months in patients ≥ 80 years of age
A Smith1, H Flaaten2, B Marsh1
1Mater Misercordiae University Hospital, Critical Care Medicine, Dublin, Ireland; 2Haukeland University Hospital, Department of Anaesthesia, Intensive Care and Clinical Medicine, Bergen, Norway
P366 Frailty: an independent factor in predicting length of stay for critically ill
T Chandler, R Sarkar, A Bowman, P Hayden
Medway Maritime Hospital, Critical Care, Gillingham, United Kingdom
Non-frail | Frail | P value | Additional LOS in frail (adjusted model) | |
---|---|---|---|---|
All Patient LOS (Days) | 10(±9) | 15(±12) | <0.0001 | 5.5(4,7), p<<0.0001 |
Elective LOS (Days) | 8(±7) | 12(±10) | 0.001 | 4(1,6), p=0.002 |
Emergency LOS (Days) | 10(±10) | 16(±12) | <0.0001 | 6(4, 8), p<0.0001 |
Critical Care Survivors LOS (Days) | 10 (±9) | 17 (±12) | <0.0001 | 6(4, 8), p<0.0001 |
P367 Incorporating trend analysis into the intensive care individual mortality review process
M Titterington, M Moore, D Spray, A Crerar-Gilbert, A Dewhurst
St George´s University Hospitals NHS Foundation Trust, Cardiothoracic Intensive Care Unit, London, United Kingdom
P368 Prediction of postoperative patient deterioration using machine learning
T Bakkes1, E Mestrom2, N Ourahou3, M Mischi1, E Korsten3, P Serra4, A Bouwman5, S Turco1
1Eindhoven University of Technology, Electrical Engineering, Eindhoven, Netherlands; 2Catharina Hospital, Intensive Care, Eindhoven, Netherlands; 3Catharina Hospital, Eindhoven, Netherlands; 4Eindhoven University of Technology, Stochastics W&I group, Eindhoven, Netherlands; 5Catharina Hospital, Anesthesiology, Eindhoven, Netherlands
P369 One-year mortality of patients with a malignancy admitted unplanned to the ICU: a large cohort study between 2008 and 2017 in the Netherlands
EN Van der zee1, F Termorshuizen2, J Bakker1, DD Benoit3, NF De Keizer2, EJ Kompanje4, WJ Rietdijk4, JL Epker4
1Erasmus MC University Medical Center, 1. Department of Intensive Care, Rotterdam, Netherlands; 2Amsterdam University Medical Center, Department of Medical Informatics, Amsterdam, Netherlands; 3Ghent University Hospital, 7. Department of Intensive Care, Ghent, Belgium; 4Erasmus MC University Medical Center, Department of Intensive Care, Rotterdam, Netherlands
Cohort 1 Hematological malignancy (n=10,401) | Cohort 2 Solid malignancy (n=35,920) | Cohort 3 General ICU population (n=423,984) | |
---|---|---|---|
ICU mortality | 2969 (28.6%) | 4890 (13.6%) | 52864 (12.5%) |
Hospital mortality | 3724 (37.9%) | 6916 (20%) | 65026 (16.4%) |
1-year mortality | 5916 (60.1%) | 15606 (46.2%) | 111328 (28.3%) |
Mean LOS ICU (days) | 5.6 | 3.1 | 3.9 |
P370 Drug abusers in the ICU – do they fare worse than non-abusers? A comparative retrospective study
TM Mann1, M Salim2, N Kumar3, L Yu4, P Lin4, K Ho4, KK Kaye3
1Assuta Medical Center, Department of Intensive Care, Ashdod, Israel; 2Detroit Medical Center, Department of Medicine, Detroit, United States; 3Detroit Medical Center, Department of Medicine, Detroit, United States; 4Wayne State University, Detroit, United States
P371 Treatment escalation plans in discharged patients from neuro and cardiac ICU
AR Rondal Rivera
St George´s Hospital NHS Trust, Cardiothoracic Intensive Care Unit, London, United Kingdom
P372 A retrospective analysis of independent risk factors of late death in septic shock survivors
C Sivakorn1, C Permpikul2, S Tongyoo2
1Faculty of Tropical Medicine, Mahidol University, Department of Clinical Tropical Medicine, Bangkok, Thailand; 2Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Variables | Hospital Mortality Adjusted HR (95%CI) | p-value |
---|---|---|
HAP/VAP | 3.24 (1.94, 5.43) | <0.001* |
SOFA score at 72 hours after weaning off NE | 1.12 (1.04, 1.19) | 0.001* |
Fluid (ml) 72 hours after discontinuation of NE | 1.01 (1.01, 1.02) | 0.008* |
Albumin level | 0.57 (0.39, 0.84) | 0.004* |
P373 Can we rely on functional capacity to predict ICU mortality?
JC Garbuglio Araujo da Silva1, C Coutinho1, MA Filho2, D Fernandes1, T Giraldi1, T Santos1
1University of Campinas, School of medical sciences, Campinas, Brazil; 2University Medical Center Groningen, University Medical Center Groningen, Holland, Netherlands
P374 Adherence to regulations regarding do-not resuscitate orders in a Swedish hospital
E Piscator1, K Göransson2, E Boström3, K Rakovic4, S Forsberg5, J Herlitz6, M Holzmann7, T Djärv5
1Karolinska Institutet, Center for Resuscitation Science, Department of Medicine Solna, Stockholm, Sweden; 2Karolinska Institutet, Department of Medicine, Solna, Stockholm, Sweden; 3Karolinska University Hospital, Function of Emergency Medicine, Solna, Stockholm, Sweden; 4Karolinska University Hospital, Function of Emergency Medicine, Stockholm, Sweden; 5Karolinska Institutet, Center for Resuscitation Science, Department of Medicine, Solna, Stockholm, Sweden; 6University of Borås, Center of Prehospital Research, Faculty of Caring Science, Work-life and Welfare, Borås, Sweden; 7Karolinska Institutet, Department of Medicine, Huddinge, Stockholm, Sweden
DNAR documents total, No. | 3583 |
Documented consent with pat, No. | 600 |
Documented consent not achievable, No. | 1432 |
Documentation regarding consent absent, No. | 1551 |
Documented consent with pat and next of kin, No | 114 |
Documented consent with next of kin, No | 664 |
Documented consent other licensed caregiver, No | 1101 |
Abbreviation: DNAR, do-not attempt resuscitation |
P375 Ethical conflicts in decision-making about respiratory support in critical situations
Á Estella1, R Viciana2
1University Hospital of Jerez, Critical Care Unit. Hospital of Jerez., Jerez, Spain; 2University Hospital of Jerez, Oncology, Jerez, Spain
P376 The Norwegian ETHICUS II data
A Robertsen1, TA Aasmundstad1, BÅ Sjøbø2, T Legernæs3, M Flückiger4, E Søreide5, K Dybwik6, J Røe Ballestad7, A Haavind8, P Klepstad on behalf of the Norwegian ETHICUS II investigators9
1Oslo University Hospital, Department of Anesthesiology and Critical Care, Oslo, Norway; 2Haukeland University Hospital, Department of Anesthesiology and Critical Care, Bergen, Norway; 3Hamar Hospital, Department of Anesthesiology and Critical Care, Hamar, Norway; 4Akershus University Hospital, Department of Anesthesiology and Critical Care, Oslo, Norway; 5Stavanger University Hospital, Department of Anesthesiology and Critical Care, Stavanger, Norway; 6Nordland University Hospital, Department of Anesthesiology and Critical Care, Bodø, Norway; 7Drammen Hospital, Department of Anesthesiology and Critical Care, Drammen, Norway; 8University Hospital of Northern Norway, Department of Anesthesiology and Critical Care, Tromsø, Norway; 9St Olav University Hospital, Department of Anesthesiology and Critical Care, Trondheim, Norway
Reason | N | % |
---|---|---|
Unresponsive to maximal therapy | 153 | 39 |
Neurological prognosis | 108 | 27 |
Poor quality of life | 26 | 7 |
Chronic disease | 40 | 10 |
Age | 9 | 2 |
Patient request | 7 | 2 |
Other | 53 | 13 |
P377 Barriers and facilitators to framing inpatient goals of care: physicians’ perceptions
A Ghosh1, S Lussier2
1The Northern Hospital, Intensive Care Unit, VicToria, Australia; 2The Northern Hospital, Intensive Care, State: Victoria, Australia
Demographics | Role, Qualifications, Gender, speciality training |
Decision making and GOPC | Confidence, responsibility, barriers, facilitators |
Discussion of GOPC | Levels of confidence, barriers, facilitators |
P378 Physician-related variability in end-of-life decisions
LB Block1,2, AS Nordenskjöld Syrous1
1Dpt of Anesthesia and Intensive Care, University of Gothenburg, Gothenburg, Sweden; 2Dpt of Anesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden.
Theme | Codes | Quotes |
Individual variability | Views on acceptable outcomes | “Will this patient really leave the hospital alive, and in that case, in what condition will the patient be?” (R 1) |
Individual variability | Values | “I am trying to actively think about not treating marginalized people in any other way than others. But I think perhaps it may be that people like heavy drug abusers may receive more limitations than others, based on medical factors, like they probably have low quality of life, small physiological reserves and may have low compliance to any aftercare”. (R16) |
Individual variability | Fear of criticism | “The fear consists of that I may misjudge the patient’s possibilities for recovery and therefore withdraw LST too early. That it could evoke criticism from colleagues that were not directly involved and might have made another decision. Also there is this fear of liability, of being subject to a process of some kind” (R4). |
P379 Can the functional capacity prior to hospitalization predict limitation of life-sustaining therapy in medical ICU patients?
JC Garbuglio araujo da Silva1, C Coutinho1, MA Filho2, D Fernandes1, T Giraldi1, T Santos1
1University of Campinas, School of medical sciences, Campinas, Brazil; 2University Medical Center Groningen, University Medical Center Groningen, Holland, Netherlands
P380 Variation in SOFA predicted mortality based on infection site
RD Pawar1, J Shih1, L Balaji2, A Grossestreuer2, P Patel3, M Donnino4, A Moskowitz5
1Beth Israel Deaconess Medical center, Internal Medicine, Boston, United States; 2Beth Israel Deaconess Medical center, Emergency Medicine, Boston, United States; 3Beth Israel Deaconess Medical center, Pharmacy, Boston, United States; 4Beth Israel Deaconess Medical center, Emergency and Critical Care Medicine, Boston, United States; 5Beth Israel Deaconess Medical center, Pulmonary and Critical Care Medicine, Boston, United States
P381 Rethinking markers of organ failure
D Plecko1, N Bennett1, IF Ukor2, R Bellomo3
1ETH Zürich, Seminar für Statistik, Zürich, Switzerland; 2East Kent University Hospital, East Kent University Hospital, Kent, United Kingdom; 3Monash University, Faculty of Medicine, Melbourne, Australia
P382 Acute organ failure in cancer patients while on systemic cancer treatment, a cohort study
S Coelho1, MT Ribeiro2, I Pereira1, D Duarte2, A Afonso1, I Vieira1, S Pinelas1, B Pereira3, N Sousa1, F Filomena3
1Instituto Português de Oncologia do Porto, Medical Oncology, Porto, Portugal; 2Instituto Português de Oncologia do Porto, Oncohematology, Porto, Portugal; 3Instituto Português de Oncologia do Porto, Intensive Care Unit, Porto, Portugal
P383 A severity-of-illness score in patients with tuberculosis requiring intensive care
U Lalla, E Irusen, B Allwood, J Taljaard, C Koegelenberg
Tygerberg Academic Hospital, Internal Medicine, Division of Pulmonology and ICU, Cape Town, South Africa
Total (n=78) | Survivors (n=37) | Non-survivors (n=41) | Mortality (%) | |
---|---|---|---|---|
6-point severity-of-illness score: | ||||
<3 | 28 | 19 | 9 | 32.1% |
≥3 | 50 | 18 | 32 | 64.0% |
Revised 4-point severity-of-illness score: | ||||
≤2 | 41 | 29 | 12 | 29.3% |
≥3 | 37 | 8 | 29 | 78.4% |
P384 The impact of chronic critical illness on survival and quality of life of patients after ICU discharge - a defining analysis of chronic critical illness
P Berto1, J Haas2, R Rosa3, C Teixeira1, T Cavalcanti3, D Sganzerla3, T Lisboa1, G Friedman4
1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; 2Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; 3Hospital Moinhos de Vento, Porto Alegre, Brazil; 4Universidade Federal do Rio Grande do Sul, PPG Ciências Pneumológicas, Porto Alegre, Brazil
P385 Simple predictive score for pulmonary complications in mechanically ventilated patients in surgical intensive unit
A Piriyapatsom, O Chintabanyat, A Trisukhonth, O Chaiwat, S Kongsayreepong
Faculty of Medicine Siriraj Hospital, Anesthesiology, Bangkok, Thailand
P386 Five-year impact of ICU-acquired neuromuscular complications: a prospective, observational study
N Van Aerde1, P Meersseman2, Y Debaveye1, A Wilmer1, J Gunst1, MP Casaer1, F Bruyninckx3, R Gosselink4, G Van den Berghe1, G Hermans1
1KU Leuven, Department of Cellular and Molecular Medicine, Leuven, Belgium; 2KU Leuven, Medical Intensive Care Unit, Leuven, Belgium; 3UZ Leuven, Department of Physical Medicine and Rehabilitation, Leuven, Belgium; 4KU Leuven, Department of Rehabilitation Sciences, Leuven, Belgium
P387 Mortality in high-risk admissions in low-volume versus high-volume intensive care units
D Burke1, R Dwyer2
1Beaumont Hospital, Intensive Care Unit, Dublin, Ireland; 2Beaumont Hospital, Beaumont Hospital, Dublin, Ireland
P388 Cognitive and mental assessment in a general intensive care unit (ICU) population one year after hospital discharge: preliminary results of a prospective study
V Mantziou1, A Kotanidou1, E Jahaj1, AG Vassiliou2, E Kampisiouli1, I Dimopoulou1
1National & Kapodistrian University of Athens, 1st Department of Critical Care Medicine & Pulmonary Services, Athens, Greece; 2National & Kapodistrian University of Athens, 1st Department of Critical Care Medicine & Pulmonary Services, GP Livanos and M Simou Laboratories, Athens, Greece
P389 The predictive value of phase angle on 6 month survival after ICU admission
F Stellingwerf, M Koopmans, H Buter, EC Boerma
Medical Center Leeuwarden, Intensive Care, Leeuwarden, Netherlands
P390 Risk factors for weakening of activity of daily living during admission after acute care with infection
H Nakano, M Mochizuki, H Naraba, Y Takahashi, T Sonoo, H Hashimoto, K Nakamura
Hitachi General Hospital, Department of Emergency and Critical Care Medicine, Hitachi, Japan
P391 Does cognitive function play a role in readmission after ICU discharge? A pilot study
C Robinson1, JM McPeake1, P MacTavish1, T Quasim2, P Henderson2
1NHS Greater Glasgow and Clyde, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom; 2University of Glasgow, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom
P392 Readmission after discharge home from critical care: a qualitative study
C Robinson1, F Nicolson1, P MacTavish1, T Quasim2, JM McPeake1
1NHS Greater Glasgow and Clyde, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom; 2University of Glasgow, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom
P393 Frailty screening tools comparison in critically ill patients: a post-hoc analysis of a multicenter prospective cohort
LU Taniguchi1, Q Ibrahim2, LC Azevedo3, H Stelfox4, S Bagshaw5
1Hospital Sirio Libanes, Intensive Care Unit, Sao Paulo, Brazil; 2McMaster University, Department of Health Research Methods, Evidence, and Impact, Hamilton, Canada; 3Hospital Sirio Libanes, Instituto Sirio Libanes de Ensino e Pesquisa, Sao Paulo, Brazil; 4University of Calgary, Department of Critical Care Medicine, Cummings School of Medicine, Calgary, Canada; 5University of Alberta, Department of Critical Care Medicine, Faculty of Medicine and Dentistry, Alberta, Canada
P394 Impact of a post-intensive care syndrome (PICS) prevention bundle in critically ill patients at ICU discharge and follow-up
LA Costa hirai, CR Dos Santos, F De Souza Trindade Neto, VF Silva de Araújo, A Da Luz Leitão, W Sousa Montenegro, KT Passos Nishiwaki, M Martins Silva, JR Araújo de Azevedo
São Domingos Hospital, Intensive Care Unit, São Luís, Brazil
Low (n=122) | Intermediate (n=113) | High (n=117) | p-value | |
---|---|---|---|---|
PICS, % ± SD | 90 ± 73 | 87 ± 76 | 87 ± 74 | 0.834 |
Anxiety, % ± SD | 31 ± 26 | 25 ± 23 | 34 ± 29 | 0.578 |
Depression, % ± SD | 20 ± 17 | 21 ± 19 | 19 ± 16 | 0.816 |
Cognitive dysfunction, % ± SD | 64 ± 54 | 58 ± 54 | 64 ± 57 | 0.837 |
Mobility, % ± SD | 48 ± 40 | 44 ± 40 | 40 ± 35 | 0.641 |
Strength, % ± SD | 9 ± 7 | 7 ± 6 | 4 ± 3 | 0.408 |
Nutrition, % ± SD | 21 ± 17 | 8 ± 7 | 7 ± 5 | 0.007 |
P395 Does sleep deprivation continue beyond intensive care in critical illness survivors: findings from a larger phenomenological study
AC Tembo
University of Sydney, Faculty of Health and Medicine, Susan Wakil Nursing School, Sydney, Australia
P396 Post intensive care syndrome after cardiothoracic critical care: 1 year outcomes and the effect of a complex multi-professional intervention
P Henderson1, I Quasim2, L Davey3, M Shaw4, T Quasim5, J McPeake5
1University of Glasgow, Department of Anaesthesia and Intensive Care medicine, Glasgow, United Kingdom; 2Golden Jubilee National Hospital, Cardiothoracic Anaesthesia and Critical Care, Glasgow, United Kingdom; 3Golden Jubilee National Hospital, Cardiothoracic Critical Care, Glasgow, United Kingdom; 4NHS Greater Glasgow & Clyde, Department of Clinical Physics and Bioengineering, Glasgow, United Kingdom; 5University of Glasgow, Department of Anaesthesia and Intensive Care Medicine, Glasgow, United Kingdom
EQ-5D-5L Domain | Clinic baseline | 3 months | 12 months |
---|---|---|---|
Problems with mobility (%) | 56 | 50 | 45 |
Problems with self-care (%) | 40 | 33 | 36 |
Problems with usual activities (%) | 80 | 61 | 55 |
Pain / discomfort (%) | 76 | 72 | 64 |
Anxiety / depression (%) | 64 | 39 | 45 |
Mean EQ-VAS score (0-100) | 70 | 78 | 78 |
P397 Frailty: a predictor of mortality amongst critical care survivors independent of age
A Munro, P Hayden, R Sarkar
Medway Maritime Hospital, Intensive Care Unit, Gillingham, United Kingdom
Mortality rate in frail | Mortality rate in non-frail | Unadjusted OR | Adjusted OR | |
---|---|---|---|---|
All patients | 30.2% | 9.5% | 4.14 (2.84, 6.05) P<0.001 | 2.25 (1.36,3.71) P<0.001 |
Emergency patients | 36.3% | 16.5% | 2.9 (1.95,4.31) P<0.001 | 1.64 (0.97, 2.77) P=0.06 |
Critical care survivors | 11.8% | 1.2% | 11.4 (4.6, 27.9) P<0.001 | 4.19 (1.6, 11.1) P=0.004 |
P398 Age versus clinical frailty score for prognostication in emergency critical care admissions
C Donnelly, P Hayden, R Sarkar, A Bowman
Medway Maritime Hospital NHS Foundation Trust, Critical Care, Gillingham, United Kingdom
P399 The impact of chronic critical illness on the development of post ICU syndrome: a Brazilian cohort study
P Berto1, S Glaeser2, LF Martins2, J Haas3, D Sganzerla2, R Rosa2, T Lisboa1, C Teixeira1, G Friedman4
1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; 2Hospital Moinhos de Vento, Porto Alegre, Brazil; 3Hospital de Cínicas de Porto Alegre, Porto Alegre, Brazil; 4Universidade Federal do Rio Grande do Sul, PPG Ciências Pneumológicas, Porto Alegre, Brazil
P400 Association of white blood cell count with one-year mortality after cardiac arrest
H Vuopio1, MB Skrifvars1, R Raj2, S Bendel3, M Reinikainen4, PT Pekkarinen5
1Helsinki University Hospital, Department of Emergency Care Services, Helsinki, Finland; 2Helsinki University Hospital, Department of Neurosurgery, Helsinki, Finland; 3Kuopio University Hospital, Division of Intensive Care Medicine, Kuopio, Finland; 4Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland; 5Helsinki University Hospital, Division of Intensive Care Medicine, Department of Anaesthesiology, Helsinki, Finland
P401 Risk factors for dysphagia in ICU patients following invasive mechanical ventilation
P Zuercher, NV Schenk, C Moret, D Berger, R Abegglen, JC Schefold
University Hospital Bern, Department of Intensive Care Medicine, Bern, Switzerland
P402 Optimizing Subsequent CARdiovascular Medication Re-introduction in the Intensive Care Unit: a retrospective study (OSCAR)
ME Boisjoly1, C Lavigne1, L Burry2, N Tabbara2, HT Wang3
1Maisonneuve-Rosemont hospital, Department of medicine, division of internal medicine, Montreal, Canada; 2Sinai Health and University of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, Canada; 3Maisonneuve-Rosemont Research Centre, Department of medicine, division of internal and critical care medicine, Montreal, Canada
Variable | Represcribed N=40 | Not represcribed N=40 | Odds ratio (95 % CI) | p-value |
---|---|---|---|---|
Age, median (IQR) | 72 (12.5) | 75 (12.5) | 1.04 (0.99-1.10) | 0.10 |
CKD, N (%) | 7 (17.5) | 13 (32.5) | 2.15 (0.78-5.92) | 0.14 |
CAD, N (%) | 10 (25.0) | 17 (42.5) | 2.22 (0.86-5.74) | 0.10 |
SOFA score, median (IQR) | 3 (3.0) | 5 (3.0) | 1.20 (1.00-1.43) | 0.045 |
APACHE II score, median (IQR) | 10 (13.0) | 16.5 (11.0) | 1.04 (0.98-1.11) | 0.17 |
Vasopressor, N (%) | 10 (25.0) | 22 (55.0) | 3.67 (1.42-9.47) | 0.007 |
P403 Predicting medication related problems in a post-ICU population using demographic and in-ICU clinical data
C Purdie1, P MacTavish2, T Quasim1, P Henderson1, J McPeake2, M Shaw3
1University of Glasgow, School of Medicine, Glasgow, United Kingdom; 2Glasgow Royal Infirmary, Intensive Care Unit, Glasgow, United Kingdom; 3Glasgow Royal Infirmary, Clinical Physics Department, Glasgow, United Kingdom
P404 Categorising medication related problems in a post-ICU population
C Purdie1, P Henderson1, T Quasim1, J McPeake2, M Shaw3, P MacTavish2
1University of Glasgow, School of Medicine, Glasgow, United Kingdom; 2Glasgow Royal Infirmary, Intensive Care Unit, Glasgow, United Kingdom; 3Glasgow Royal Infirmary, Clinical Physics Department, Glasgow, United Kingdom
P405 Implementation of physiotherapy early after cardiac surgery: the Onassis cardiac surgery center experience
V Raidou1, S Dimopoulos2, F Chatzivasiloglou1, K Sakki1, A Robola2, K Papadopoulos2, A Tasouli2, I Kriaras2, S Nanas1, A Karabinis2
1National and Kapodestrian University of Athens, Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, Athens, Greece; 2Onassis Cardiac Surgery Center, Cardiac Surgery ICU, Athens, Greece
P406 Ventilator associated pneumonia (VAP) in tracheoventilated home patients
F Righetti1, E Colombaroli2
1Intensive Care Unit, Fracastoro Hospital, Emergency Department, San Bonifacio, Verona, Italy; 2Intensive Care Unit, Fracastoro Hospital, San Bonifacio, Verona, Italy
P407 Prognostic factors of heterotopic ossification in critically ill patients
AG Vassiliou1, I Dimopoulou2, E Jahaj2, Z Mastora2, SE Orfanos2, A Kotanidou2
1National & Kapodistrian University of Athens, 1st Department of Critical Care Medicine & Pulmonary Services, GP Livanos and M Simou Laboratories, Athens, Greece; 2National & Kapodistrian University of Athens, 1st Department of Critical Care Medicine & Pulmonary Services, Athens, Greece
P408 Improving the transition of care from the intensive care unit to wards
C Cunningham, M McKenna, C Patterson, M Doohan, M Duffy
Mater Infirmorium Hospital, Belfast, United Kingdom
P409 E-health outside the ICU: a wearable in telemonitoring respiratory and heart rates as part of the Early Warning Score
EJ Van lieshout1, J Hoekstra2, R Voorn3, E Maij4, M Regeling4, I Bruining5, R Lo5
1Amsterdam University Medical Center, Intensive Care and Mobile Intensive Care Unit, Amsterdam, Netherlands; 2Amsterdam University Medical Center, dept. of Hematology, Amsterdam, Netherlands; 3Amsterdam University Medical Center, Dept. of medical engineering, Amsterdam, Netherlands; 4Amsterdam University Medical Center, Dept. of EPIC Services, Amsterdam, Netherlands; 5Amsterdam University Medical Center, Dept. of ICT, Amsterdam, Netherlands
- unseamlessly transmitting of both heart and respiratory rates including appropriate movements filtering to the nurse's smartphones
- direct uploading into electronic health record with automated EWS calculation
- nurse driven protocol on EWS follow up.
P410 Hospital discharges: from the intensive care unit to home
CE Bosso1, PC Dutil Ribeiro2, FA Falconi de Oliveira Cícero2, RD Caetano3, A Pireneus Cardoso4, L Manata Vanzella5, LC Marques Vanderlei5
1Instituto do Coração de Presidente Prudente, Cardiology, Presidente Prudente, Brazil; 2UNOESTE, Presidente Prudente, Brazil; 3Santa Casa de Misericórdia de Presidente Prudente, Presidente Prudente, Brazil; 4Instituto do Coração de Presidente Prudente, Presidente Prudente, Brazil; 5UNESP, Presidente Prudente, Brazil
Discharge to home | Discharge to ward | P | |
---|---|---|---|
Age | 66.23±13.93 | 66.76±13.74 | 0.398 |
Gender | 42.90% F / 57.10% M | 37.60% / F 62.40% M | 0.044 |
SAPS3 score | 40.75±9.99 | 43.42±12.64 | 0.000 |
Mechanical ventilation | 2.90% | 18.90% | 0.000 |
Vasopressors | 13.90% | 32.80% | 0.000 |
Blood transfusion | 1.90% | 4.10% | 0.032 |
ICU lengh of stay | 2.59±2.64 | 3.30±3.99 | 0.000 |
P411 Appropriateness of antimicrobial use among septic patients managed by the critical care response team: an opportunity for improvement through de-escalation
S Al Qahtani1, H Balkhy2, A Ali3, K Aljufy4, A Alsaed5
1King Abdulaziz Medical City, ICU, Riyadh, Saudi Arabia; 2King Abdulaziz Medical City, WHO, Riyadh, Saudi Arabia; 3King Abdulaziz Medical City, IM, Riyadh, Saudi Arabia; 4King Abdulaziz Medical City, Pharmacy, Riyadh, Saudi Arabia; 5King Abdulaziz Medical City, Biostatistics, Riyadh, Saudi Arabia
P412 Dynamic colonization with multidrug-resistant bacteria in an infectious diseases intensive care unit
D Miclaus1, L Herbel1, T Szilagyi2, M Flonta3, A Dicea2, A Muntean1, M Lupse2
1University Hospital of Infectious Diseases, ICU, Cluj-Napoca, Romania; 2University Hospital of Infectious Diseases, Infectious Diseases, Cluj-Napoca, Romania; 3University Hospital of Infectious Diseases, Laboratory, Cluj-Napoca, Romania
P413 Impact of candidaemia on mortality of critically ill burned patients
A Agrifoglio, L Cachafeiro, E Herrero, M Sánchez, A García de Lorenzo
Hospital Universitario La Paz, Intensive Care Medicine Service, Madrid, Spain
P414 A cost minimisation analysis of PCR point of care testing for influenza versus PCR lab testing
M Mclaughlin1, D Boyers2
1Glasgow Royal Infirmary, Anaesthetics/Critical Care, Glasgow, United Kingdom; 2Health Economics Research Unit, Health Economist, Aberdeen, United Kingdom
P415 Monobacterial v/s polibacterial multidrug-resistant Klebsiella spp. ventilator-associated pneumonia: factors associated with mortality
D Adukauskiene, A Dambrauskiene, A Ciginskiene
Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania
P416 Ventilator-associated pneumonia due to multidrug-resistant Klebsiella spp.: antibacterial resistance and predictors of ICU mortality
D Adukauskiene, A Dambrauskiene, A Ciginskiene
Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania
P417 Role of deoxyribonucleic acid in microbial biofilm in pathogenesis of bacterial infection
V Ziamko1, A Dzyadzko2, V Okulich1
1Vitebsk State Medical University, Vitebsk, Belarus; 2Minsk Scientific and Practical Center of Surgery, Transplantation and Hematology, Minsk, Belarus
P418 The clinical impact of 24h/7day blood culture identification using the genmark ePlex blood culture panels
A Krifors1, D Heimer2, S Golbob2, Z Omar2, C Svensson2, G Rådberg2, C Carlander3
1Västmanlands sjukhus Västerås, Department of Infectious Diseases, Västerås, Sweden; 2Department of Clinical Microbiology, Department of Clinical Microbiology, Västerås, Sweden; 3Department of Infectious Diseases, Department of Infectious Diseases, Västerås, Sweden
P419 Impact of rising Klebsiella pneumoniae infections and its resistance on the outcome of hospitalized patients in the intensive care unit of a tertiary healthcare hospital, Saudi Arabia
A Al bshabshe1, M R.P. Joseph2, A Assiri3, M Hamid2, M Bahis4, I Assiry5, A Al-Hakami6
1King Khalid university, Medicine/Critical Care, Abha, Saudi Arabia; 2King Khalid university, Department of Microbiology, Abha, Saudi Arabia; 3King Khalid university, Critical Care Department, Abha, Saudi Arabia; 4Aseer central hospital, critical Care Department, Abha, Saudi Arabia; 5Aseer central hospital, Abha, Saudi Arabia; 6King Khalid university, department of Microbiology, Abha, Saudi Arabia
P420 Patterns of presentation and predictors of ICU mortality among HIV infected patients
AE Laher1, RW Maphula1, GA Richards2
1University of the Witwatersrand, Emergency Medicine, Parktown, Johannesburg, South Africa; 2University of the Witwatersrand, Critical Care, Parktown, Johannesburg, South Africa
P421 Impact of beta-lactamase detection reagent on rapid diagnosis of ESBL-producing pathogens using urine samples in patients with gram-negative bacteriuria
J Yoshimura1, Y Ooi2, Y Umemura1, K Yamakawa1, S Fujimi1
1Osaka General Medical Center, Division of Trauma and Surgical Critical Care, Osaka, Japan; 2Osaka General Medical Center, Department of Clinical Laboratory, Osaka, Japan
P422 Effect of bundle approach on preventing hospital-acquisition of drug-resistant pathogens in intensive care units
A Ota1, M Kawanami1, J Yoshimura2, Y Umemura2, K Yamakawa2, S Fujimi2
1Osaka General Medical Center, Nursing Department, Osaka, Japan; 2Osaka General Medical Center, Division of Trauma and Surgical Critical Care, Osaka, Japan
P423 Outcomes in patients (pts) with failure of initial antibiotic therapy for hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) prior to enrollment in the phase 3 ASPECT-NP trial of ceftolozane/tazobactam (C/T) vs. meropenem (MEM)
M Kollef1, JF Timsit2, I Martin-Loeches3, RG Wunderink4, JA Huntington5, E Jensen5, CJ Bruno5, B Yu5, DJ Wolf5, EG Rhee5
1Washington University School of Medicine, St. Louis, MO, United States; 2Université Paris Diderot/Hôpital Bichat, Paris, France; 3St James´ Hospital, Dublin, Ireland; 4Northwestern University Feinberg School of Medicine, Chicago, IL, United States; 5Merck & Co., Inc., Kenilworth, NJ, United States
P424 Impact of team-based approach on preventing catheter-related bloodstream infection in critically ill setting
A Hamana1, A Sawada1, J Yoshimura2, Y Umemura2, K Yamakawa2, S Fujimi2, Y Sakajo1
1Osaka General Medical Center, Department of Pharmacy, Osaka, Japan; 2Osaka General Medical Center, Division of Trauma and Surgical Critical Care, Osaka, Japan
P425 Assessment of antimicrobial susceptibility of the most common Gram-negative intensive care unit (ICU) respiratory pathogens in deciding antimicrobial therapy
P Moise1, M Gonzalez1, I Alekseeva1, D Lopez2, B Akrich3, B Akrich3, A DeRyke1, M Hackel4, M Motyl5
1Merck & Co., Inc, Medical Affairs, Kenilworth, United States; 2MSD, Medical Affairs, Madrid, Spain; 3MSD France, Medical Affairs, Paris, France; 4IHMA, Microbiology, Schaumburg, United States; 5Merck & Co., Inc, Microbiology, Kenilworth, United States
P426 Evaluation of compliance of ICU staff for VAP prevention strategies on the outcome of patients
A Kaur
Fortis Hospital, Critical Care, Mohali, India
P427 Ventilation-associated pneumonia prevention bundle (VAP-p) efficacy in critically ill children mechanically ventilated for more than 48 hours
I Vitali1, AM Dell´Anna2, L Dassatti3, O Genovese1, M Piastra1, P Filetici3, M Antonelli2, G Conti1
1Fondazione Policlinico Universitario A. Gemelli IRCCS, Paediatric Intensive Care Unit, Roma, Italy; 2Fondazione Policlinico Universitario A. Gemelli IRCCS, Intensive Care Unit, Roma, Italy; 3Fondazione Policlinico Universitario A. Gemelli IRCCS, Oral Surgery, Roma, Italy
P428
P429 ICU-related Gram-negative bacteremia: outcome and the role of colistin susceptibility
M Karvouniaris, T Zafeiridis, P Katsiafylloudis, A Palioura, M Chatzimichail, A Papadogoulas, P Papamichalis, D Papadopoulos, S Karagiannis, A Komnos
General Hospital of Larissa, ICU, Larisa, Greece
P430 Characterization of resistance mechanisms affecting ceftolozane/tazobactam in Enterobacterales and Pseudomonas aeruginosa ICU isolates using whole genome sequencing (STEP study)
M Hernández-garcia1, CC Chaves2, JM Melo-Cristino3, DS Silva4, AR Vieira5, MP F. Pinto6, JD Diogo7, EG Gonçalves8, JR Romano9, RC Cantón1
1Hospital Ramón y Cajal-IRYCIS, Microbiology Department, Madrid, Spain; 2Centro Hospitalar Universitário de Coimbra, Microbiology Department, Coimbra, Portugal; 3Centro Hospitalar Universitário Lisboa Norte, Microbiology Department, Lisboa, Portugal; 4Centro Hospitalar Universitário do Porto, Microbiology Department, Porto, Portugal; 5Centro Hospitalar Universitário São João, Microbiology Department, Porto, Portugal; 6Centro Hospitalar Universitário Lisboa Central, Microbiology Department, Lisboa, Portugal; 7Hospital Garcia de Orta, Microbiology Department, Almada, Portugal; 8Centro Hospitalar de Lisboa Ocidental, Microbiology Department, Lisboa, Portugal; 9MSD Portugal, Medical Affairs, Paço de Arco, Portugal
P431 Clostridium difficile infection in Lithuania
D Adukauskienė, R Mickus, A Dambrauskienė
Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
P432 Ceftolozane/tazobactam pharmacokinetics in critically ill patients on continuous venovenous hemodiafiltration
SM Martinez castro1, EB Bárcena Barreto2, EU Utrera2, JA Carbonell2, RF Ferriols3, GA Aguilar2
1Hospital Clinico Universitario, Department of Anesthesiology and Intensive Care, Valencia, Spain; 2Hospital Clínico Universitario De Valencia, Servicio De Anestesiología, Reanimación Y Tratamiento Del Dolor, Valencia, Spain; 3Hospital Clínico Universitario De Valencia, Pharmacy, Valencia, Spain
P433 Alfatorquetenovirus: a new sepsis biomarker?
SM Martinez castro1, N Segura Marín2, E Albert3, D Navarro3, P Pardo2, Ja Carbonell2, E Carbonell4, G Aguilar2
1Hospital Clinico Universitario, Department Of Anesthesiology And Intensive Care, Valencia, Spain; 2Hospital Clínico Universitario De Valencia, Servicio De Anestesiología, Reanimación Y Tratamiento Del Dolor, Valencia, Spain; 3Hospital Clínico Universitario De Valencia, Microbiology Department, Valencia, Spain; 4Hospital Clínico Universitario De Valencia, Intensive Care Unit, Valencia, Spain
P434 Identifying synergistically nephrotoxic antimicrobial regimens in patients with sepsis: two nationwide multicenter registries in Japan
N Meguro1, J Yoshimura1, K Yamakawa2, Y Umemura2, S Fujimi1, H Ogura2, T Abe2, S Gando2, Y Otomo2
1Division of Trauma and Surgical Critical Care, Osaka General Medical Center, emergency, Osaka, Japan; 2Japanese Association for Acute Medicine Sepsis Prognostication in Intensive Care Unit and Emergency Room (SPICE) study group, emergency, Tokyo, Japan
P435 Epidemiology of nosocomial infections caused by carbapenem resistance Klebsiella pneumoniae producing KPC, NDM and OXA-48 carbapenemases in burn ICU
V Bagin, M Astafyeva, N Nevskaya, E Lukina, I Korobko, V Rudnov
City Clinical Hospital No 40, ICU, Yekaterinburg, Russia
P436 Vancomycin adsorption during in vitro model of hemoperfusion with HA330 cartridge
I Godi1, A Lorenzin2, S De Rosa3, A Sandini4, M De Cal5, P Navalesi1, C Ronco5
1Department of Medicine - DIMED, Section of Anesthesiology and Intensive Care, PADUA, Italy; 2San Bortolo Hospital, International Renal Research Institute of Vicenza, Vicenza, Italy; 3San Bortolo Hospital, Section of Anesthesiology and Intensive Care, Vicenza, Italy; 4San Bortolo Hospital, Department of Trasfusional Medicine, Vicenza, Italy; 5San Bortolo Hospital, Department of Nephrology, Dialysis and Transplantation, Vicenza, Italy
P437 The value of routine blood-borne virus (BBV) testing in the intensive care unit (ICU)
YY Tan1, M Booth2
1University of Glasgow, Glasgow, United Kingdom; 2Glasgow Royal Infirmary, Anaesthesia And Intensive Care, Glasgow, United Kingdom
P438 Assessment of the clinical significance of bacteremia causative pathogens in ICU patients
M Dementienko1, V Gusarov1, D Shilkin1, R Amaeva1, E Gricenko1, M Luzin1, I Plaksin1, D Menshikov1, D Kamyshova2, M Zamyatin1
1N. Pirogov National Medical Surgical Center, ICU, Moscow, Russia; 2N. Pirogov National Medical Surgical Center, Pharmakologist, Moscow, Russia
Subgroup | Mechanical ventilation, days* | AMT, days* | ICU LOS, days* | Hospital LOS, days* |
---|---|---|---|---|
non-ESKAPE | 5 (0-15) | 11.5 (7-20) | 12 (5-22) | 30 (17-55) |
ESKAPE | 7.5 (2-24) р=0.002 | 12 (8-21) р=0.162 | 15 (7-28.5) р=0.019 | 32 (20-57) р=0.247 |
CPR Kl.pneumoniae | 7.5 (2-26) р=0.043 | 12 (9-28) р=0.286 | 15 (8-27) р=0.169 | 31 (21.5-58) р=0.481 |
MDR Ps.aeruginosa | 11 (6-27) р=0.023 | 14 (8-21) р=0.279 | 18 (8-30) р=0.099 | 32.5 (15-49) р=0.717 |
Candida spp. | 12.5 (2-41) р=0.023 | - | 19.5 (9-41) р=0.03 | 44.5 (18-75) р=0.263 |
P439 Assessing the volume of blood taken for blood culture and culture positivity – do we need to take less blood?
TM Mann1, M Salim2, S Haider2, AH Mayo1, KK Kaye2
1Assuta medical center, Department of Intensive Care, Ashdod, Israel; 2Detroit Medical Center, Department of Medicine, Detroit, United States
P440 De-escalating antibiotics in sepsis with the use of T2MR in a 35-bed Greek university ICU
C Vrettou, E Douka, I Papachatzakis, K Sarri, E Gavrielatou, E Mizi, S Zakynthinos
1st ICU Department, University of Athens, Evangelismos General Hospital, ICU, Athens, Greece
P441 Antibiotic stewardship in ICU. A single experience
L Forcelledo1, E García-Prieto1, L López-Amor1, E Salgado1, J Fernández Dominguez2, M Alaguero3, E García-Carús4, M Telenti5, L Cofiño1, D Escudero1
1Hospital Universitario Central de Asturias, Intensive Care Department, Oviedo, Spain; 2Hospital Universitario Central de Asturias, Microbiology department, Oviedo, Spain; 3Hospital Universitario Central de Asturias, Pharmacology department, Oviedo, Spain; 4Hospital Universitario Central de Asturias, Infectious Diseases Unit, Oviedo, Spain, 5Hospital Universitario Central de Asturias, Infectious Disease Unit, Oviedo, Spain
P442 Clinical outcomes of isavuconazole versus voriconazole for the primary treatment of invasive aspergillosis: subset analysis of Indian data from SECURE trial
P Kundu, S Kamat, A Mane
Pfizer Limited, Medical Affairs, Mumbai, India
Parameters | Overall Population (n=258) | Overall Population (n=258) | Indian Subset (n=12) | Indian Subset (n=17) |
---|---|---|---|---|
All- cause mortality (Day 42) | 48 (19) | 52 (20) | 5 (41.6) | 5 (29.4) |
Adjusted Treatment Difference | -1% | 12.2% | ||
TEAE leading to treatment discontinuation | 37 (14) | 59 (23) | 2 (16.7) | 4 (23.5) |
Ocular toxicity | 39 (15) | 69 (27) | 0 | 2 (11.8) |
Skin and Subcutaneous Tissue disorder | 86 (33) | 110 (42) | 1 (8.3) | 1 (5.9) |
Hepatobiliary disorder | 23 (9) | 42 (16) | 0 | 1 (5.9) |
P443 Ceftazidim/avibactam on OXA-23 A. baumannii ventilator associated pneumonia – does it make any sense?
C Cobilinschi, M Țigliș, A Băetu, AM Cotae, OM Melente, M Costache, T Hurmuzache, E Ciobanu, IM Grințescu
Clinical Emergency Hospital Bucharest, Anesthesiology and Intensive Care, Bucharest, Romania
P444 Impact of patient colonization on admission to intensive care on 28 and 90 days mortality
G Dabar1, C Harmouch2, E Nasser Ayoub3, Y Habli4, G Sleilaty5, J Choucair6
1Hotel Dieu de France Hospital and Saint Joseph University, Pulmonary and Critical Care, Beirut, Lebanon; 2Hotel Dieu de France Hospital and Saint Joseph University, Beirut, Lebanon; 3Hotel Dieu de France Hospital and Saint Joseph University, Anesthesia and Critical Care, Beirut, Lebanon; 4Hotel Dieu de France Hospital and Saint Joseph University, Pulmonary and Critical Care Section, Beirut, Lebanon; 5Hotel Dieu de France Hospital and Saint Joseph University, Biostatistics section, Beirut, Lebanon; 6Hotel Dieu de France Hospital and Saint Joseph University, Infectious Diseases, Beirut, Lebanon
P445 Continuous infusion vancomycin: A better option in critical care?
M Murphy1, Z Alrifai2
1Nottingham University Hospitals, Critical Care, Nottingham, United Kingdom; 2Nottingham University Hospitals, Intensive Care Medicine, Nottingham, United Kingdom
P446 Prospective cohort study of impact of BAL Biofire® Filmarray® pneumonia panel on microbial diagnosis and antibiotic prescription in ICU
M Sircar1, O Jha1, J Singh1, S Yadav1, R Kaur2
1Fortis Hospital, Pulmonology and Critical Care, Noida, UP, India; 2Fortis Hospital, Microbiology, SRL Diagnostics laboratory, Noida, UP, India
P447 Ceftaroline fosamil for treatment of severe community acquired pneumonia
S Gallego zarzosa, M López de Olivencia, J Higuera Lucas, V Quinteros Fiel, M García Godes, C Soriano Cuesta, S García Plaza, R De Pablo Sánchez
H. U. Ramón y Cajal, Intensive Medicine, Madrid, Spain
P448 Organ dysfunction in scrub typhus, incidence and risk factor
A Sarkar1, A Guha2, R Dey3
1Peerless Hospital and B.K.Roy research center, Clinical Director of Critical care unit, Kolkata, India; 2Peerless Hospital and B.K.Roy research center, DNB Internal Medicine Postgraduate Trainee, Kolkata, India; 3Peerless Hospital and B.K.Roy research center, Consultant Critical care unit, Kolkata, India
P449 Tuberculosis in intensive care medicine
T Isidoro Duarte1, M Santos2, A Dias2, N Germano1
1Curry Cabral Hospital, Central Lisbon University Hospital Center, Intensive Care Medicine Department, Lisboa, Portugal; 2Curry Cabral Hospital, Central Lisbon University Hospital Center, Infectious Diseases Department, Lisboa, Portugal
P450 Critical care management of fulminant East African sleeping sickness
D Hall1, J Harrington1, J Eapen2, S Chanda3
1Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 2NYU Langone Medical Center, Division of Infectious Disease, New York, United States; 3University Teaching Hospital, Lusaka, Zambia
P451 Lithium chloride to prevent endothelial damage by serum from septic shock patients (in vitro study)
A Kuzovlev1, A Shabanov2, O Grebenchikov1, I Kasatkina1
1Federal research and clinical center of intensive care medicine and rehabilitology, Moscow, Russia; 2Federal research and clinical center of intensive care medicine and rehabilitology; N.V. Sklifosofsky research institute of emergency medicine, Moscow, Russia
P452 Autonomic nervous system, arterial stiffness and peripheral vascular tone alterations in septic shock: are they restored after resuscitation?
M Carrara1, A Herpain2, G Baselli1, M Ferrario3
1Politecnico di Milano, Milano, Italy; 2Université Libre de Bruxelles, Erasme University Hospital, Brussels, Belgium; 3Politecnico di Milano, Dept. of Electronics, Information and Bioengineering, Milano, Italy
P453 Translational value of the microbial profile in experimental sepsis studies
SP Tallósy1, A Rutai1, L Juhász1, MZ Poles1, K Burián2, D Érces1, A Szabó1, M Boros1, J Kaszaki1
1University of Szeged, Faculty of Medicine, Institute of Surgical Research, Szeged, Hungary; 2University of Szeged, Faculty of Medicine, Institute of Clinical Microbiology, Szeged, Hungary
P454 Intra-abdominal lipopolysaccharide (LPS) clearance and inactivation in peritonitis: key roles for lipoproteins and phospholipid transfer protein (PLTP)
M Nguyen1, G Pallot2, A Tavernier2, A Dusuel2, D Masson2, L Lagrost2, PG Guinot1, T Gauthier2, B Bouhemad1
1Dijon University Medical Center, Anesthesiology and Intensive Care, Dijon, France; 2University Bourgogne Franche-Comté, INSERM, LNC UMR1231, Dijon, France
P455 Reduced ATX levels protect mice from LPS-induced endotoxemia
I Nikitopoulou1, M Theodorakopoulou2, A Katsifa3, SE Orfanos2, V Aidinis3, A Kotanidou4
1GP Livanos and M Simou Laboratories, 1st Department of Critical Care & Pulmonary Services, Medical School, National & Kapodistrian University of Athens, Athens, Greece; 22nd Department of Critical Care, Attikon University Hospital, Athens, Greece; 3BSRC Alexander Fleming, Athens, Greece; 41st Department of Critical Care & Pulmonary Services, Medical School, National & Kapodistrian University of Athens, Evangelismos Hospital, Athens, Greece
P456 Neutrophil-related genes and pneumonia
M Khadzhieva1, A Kuzovlev2, A Gracheva3, L Salnikova1
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences; Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia; 2Federal research and clinical center of intensive care medicine and rehabilitology, Moscow, Russia; 3Federal research and clinical center of intensive care medicine and rehabilitology; N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia
eSNP, allele | Gene (up (↑)/down (↓) regulation for eSNP allele) | Resource (GTEx or eQTL blood) | P-value (GTEx / eQTL blood) | Risk allele for pneumonia in GBE (P-value) |
---|---|---|---|---|
rs11692150-C | TNFAIP6(↓) | GTEx/eQTL blood | 3.0E-7 / 6.70E-17 | rs11692150-C (0.00272) |
rs9923575-T | HP(↓) | GTEx/eQTL blood | 8.3E-5 / 7.14E-71 | rs9923575-T (0.00244) |
rs581623-C | FCAR(↓) | GTEx/eQTL blood | 8.5E-6 / 2.87E-5 | rs581623-C (0.00540) |
rs269938-T | FCAR(↑) | eQTL blood | 2.24E-5 | rs269938-T (0.00461) |
rs8111613-C | PGLYRP1(↓) | eQTL blood | 1.89E-5 | rs8111613-C (0.00342) |
P457 Association of host-derived hydrogen sulfide with neutrophil phagocytosis of multidrug resistant Pseudomonas aeruginosa
G Renieris1, P Koufargyris2, D Droggiti2, T Gkavogianni2, L Sabrakos2, E Jentho3, S Weis3, M Bauer3, A Papapetropoulos4, E Giamarellos-Bourboulis2
14th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece; 24th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece; 3Department of Anesthesiology and Intensive Care, Institute for Infectious Disease and Infection Control, Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany; 4Laboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
P458 Brain tight junction protein expression in sepsis in an autopsy series
KE Erikson1, HT Tuominen2, MV Vakkala3, JL Liisanantti4, TK Karttunen2, HS Syrjälä5, TA Ala-kokko4
1The North Estonia Medical Centre, Centre of Intensive Care, Tallinn, Estonia; 2Oulu University Hospital, Department of Pathology, Oulu, Finland; 3Oulu University Hospital, Department of Anesthesiology, Oulu, Finland; 4Oulu University Hospital, Department of Anesthesiology, Division of Intensive Care Medicine, Oulu, Finland; 5Oulu University Hospital, Department of Infection Control, Oulu, Finland
P459 Oxylipins in septic shock: a post-hoc analysis of the VANISH randomized clinical trial
TN Jones, F Al-Beidh, AC Gordon, DB Antcliffe
Imperial College London, Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, London, United Kingdom
P460 Lithium chloride influence neutrophil activation in vitro
A Kuzovlev, O Grebenchikov, A Shabanov, I Kasatkina, V Moroz
Federal research and clinical center of intensive care medicine and rehabilitology, Moscow, Russia
P461 Human host immune responses to lipopolysaccharide: A comparison study between in vivo endotoxemia model and ex vivo lipopolysaccharide stimulations using an immune profiling panel
DM Tawfik1, JM Lankelma2, L Vachot3, E Cerrato3, A Pachot3, WJ Wiersinga2, J Textoris3
1bioMerieux, Medical Diagnostic Discovery Department (MD3), Lyon, France; 2Amsterdam UMC, Amsterdam, Netherlands; 3bioMerieux, Lyon, France
P462 Are baseline levels of soluble Mer and Gas6 predictors of mortality and organ failure in septic patients? The Need-Speed trial database
F Gavelli, L Molinari, L Salmi, M Baldrighi, F Patrucco, M Bellan, PP Sainaghi, GC Avanzi, LM Castello
Università degli Studi del Piemonte Orientale, Department of Translational Medicine, Novara, Italy
P463 Glycocalyx shedding correlates with positive fluid balance and respiratory failure in patients with septic shock
N Takeyama, Y Kajita, T Terajima, H Mori, T Irahara, M Tsuda, H Kano
Aichi Medical University, Department of Emergency and Critical Care Medicine, Aichi, Japan
P464 Serial procalcitonin measurements in the intensive care unit at Hiroshima University Hospital
K Hosokawa, S Yamaga, M Fujino, K Ota, N Shime
Hiroshima University Hospital, Department of Emergency and Critical Care Medicine, Hiroshima, Japan
P465 The early diagnostics of the sepsis of newborns on mechanical ventilation
M Pukhtinskaya1, V Estrin2
1State Medical University, Department of Anesthesiology and Critical Care Medicine, Rostov on don, Russia; 2State Medical University, Rostov on don, Russia
P466 Efficacy of pancreatic stone protein in diagnosis of infection in adults: a systemic review and metaanalysis of raw patient data
J Prazak1, P Egimann2, I Irincheva3, MJ Llewelyn4, D Stolz5, LG De Guadiana-Romualdo6, R Graf7, T Reding7, HJ Klein8, YA Que1
1Inselspital, Bern University Hospital, University of Bern, Department of Intensive Care Medicine, Bern, Switzerland; 2University Hospital Medical Center (CHUV) and University of Lausanne, Department of Intensive Care Medicine, Lausanne, Switzerland; 3Inselspital, Bern University Hospital, University of Bern, Clinical Trial Unit, Bern, Switzerland; 4Brighton and Sussex Medical School, Falmer, United Kingdom; 5University Hospital Basel, Clinic of Pulmonary Medicine and Respiratory Cell Research, Basel, Switzerland; 6Santa Lucia Hospital, Clinical Chemistry Laboratory, Cartagena, Spain; 7University Hospital Zurich, Department of Visceral and Transplantation Surgery, Zurich, Switzerland; 8University Hospital Zurich, Department of Plastic Surgery and Hand Surgery, Burn Center Zurich, Zurich, Switzerland
P467 Clinical correlation of neutrophil CD64, PCT and CRP in ICU patients with sepsis/septic shock
R Patnaik1, A Azim1, V Agarwal2, P Mishra3
1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Critical Care Medicine, Lucknow, Uttar Pradesh, India; 2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Clinical Immunology, Lucknow, Uttar Pradesh, India; 3Sanjay Gandhi Postgraduate Institute of Medical Sciences, Biostatistics, Lucknow, Uttar Pradesh, India
P468 High STREM-1 levels and low monocyte HLA-DR expression are associated with nosocomial infections and mortality in septic shock patients
A Olivier1, L Jolly1, G Monneret2, T Rimmele3, M Salcedo-Magguilli1, JJ Garaud1, JM Grouin4, M Derive1, F Venet2
1INOTREM, Vandoeuvre-les-Nancy, France; 2Hospices Civils de Lyon, Immunology Laboratory, Lyon, France; 3Hospices Civils de Lyon, Anesthesia and Critical Care Medicine Department, Lyon, France; 4University of Rouen, INSERM U1219, Rouen, France
P469 Added value of serial bio-adrenomedullin measurement in addition to lactate for the prognosis of septic patients admitted to ICU
A Blet1, C De Roquetaillade1, O Hartmann2, J Schulte2, J Struck2, PF Laterre3, E Gayat1, A Mebazaa1, BG Chousterman4
1Hôpital Lariboisière, Paris, France; 2Shpingotec, Hennigsdorf, Germany; 3St Luc university hospital, Brussels, Belgium; 4Hôpital Lariboisière, Département d´Anesthésie-Réanimation, Paris, France
P470 The effect of fluid replacement in sepsis, severe sepsis and septic shock in first 24 hrs in clot quality and microstructure
S Pillai1, G Davies2, M Lawrence2, J Whitley2, PR Williams3, K Morris4, PA Evans2
1Welsh Centre for Emergency Medicine Research, Emergency Department, Morriston Hospital, Swansea, United Kingdom; 2Welsh Centre for Emergency Medicine Research, Morriston Hospital, Swansea, United Kingdom; 3Swansea University, Swansea, United Kingdom; 4Cardiff Metropolitan University, Swansea, United Kingdom
P471 Plasmatic levels of adrenomedullin during extracorporeal membrane oxygenation in patients with severe respiratory failure
G Grasselli1, M Panigada1, S De Falco1, C Novembrino2, F Cea2, A Di Modugno2, E Cipriani1, A Cucino1, A Pesenti1
1Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico, Intensive Care Unit, Milano, Italy; 2Fondazione IRCCS Ca´ Granda Ospedale Maggiore Policlinico, Clinical Laboratoy, Milano, Italy
P472 Extracellular vesicles are associated with C-reactive protein during sepsis
B Fendl, R Weiss, T Eichhorn, V Weber
Danube University Krems, Department for Biomedical Research, Krems, Austria
P473 Extracellular vesicles from activated platelets induce a shift towards proinflammatory monocyte subsets
B Fendl1, R Weiss1, T Eichhorn1, A Spittler2, V Weber1
1Danube University Krems, Department for Biomedical Research, Krems, Austria; 2Medical University of Vienna, Core Facility Flow Cytometry & Surgical Research Laboratories, Vienna, Austria
P474 Kinetics of calprotectin, procalcitonin and C-reactive protein in healthy volunteers administered intravenous endotoxin
JN Fullerton1, A Havelka2, E Segre1, RP De Maeyer1, AA Maini1, DW Gilroy1
1University College, Centre for Clinical Pharmacology, Division of Medicine, London, United Kingdom; 2Karolinska Institute, Department of Molecular Medicine and Surgery & Gentian Diagnostics AB, Stockholm, Sweden
P475 An analysis of the prognostic ability of the white blood cell count, neutrophil:lymphocyte ratio and C-reactive protein in patients with septic shock
M Chotalia1, M Bangash2, T Matthews2, D Parekh2, J Patel2
1University Hospitals Birmingham, NHS Foundation Trust, Critical Care and Anaesthesia, Birmingham, United Kingdom; 2University Hospitals Birmingham, NHS Foundation Trust, Birmingham, United Kingdom
P476 Itaconic acid, other mitochondrial and microbial metabolites in different stages of sepsis
N Beloborodova1, A Pautova1, A Sergeev1, N Fedotcheva2
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Negovsky Research Institute of General Reanimatology, Moscow, Russia; 2Institute of Theoretical and Experimental Biophysics (Russian Academy of Sciences), Pushchino, Russia
P477 Plasma-calprotectin compared with routine biomarkers for prediction of early severe event in sepsis
ÅP Parke1, DY Yu2, CU Unge3, JC Sunden-Cullberg4
1Karolinska Institutet, Department of Medicin, Karolinska Hopital Huddinge, Huddinge, Sweden; 2Karolinska Institutet, Department of Laboratory Medicin, Huddinge, Sweden; 3Karolinska Institutet, Department of Medicin Huddinge, Huddinge, Sweden; 4Karolinska Institutet, Depratment of Medicin, Huddinge, Huddinge, Sweden
P478 A mRNA host response signature accurately distinguishes bacterial and viral infections among emergency department patients
A Safarika1, J Wacker2, N Solomonidi1, G Giannikopoulos3, IM Koutelidakis4, O Liesenfeld2, T Sweeney5, EJ Giamarellos-Bourboulis1
114th Department of Internal Medicine, National and Kapodistrian University of Athens,, Athens, Greece; 2Inflammatix, Clinical Affairs, Burlingame, United States; 33Department of Internal Medicine, Syros General Hospital,, 3Department of Internal Medicine, Syros General Hospital,, Syros, Greece; 4Aristotle University of Thessaloniki, Thessaloniki, Greece; 5Inflammatix, Burlingame, United States
P479 A rapid microfluidic assay of leukocyte deformability demonstrates diagnostic utility for sepsis early in an emergency department (ED) course
H O´Neal, jr.1, A Shah2, C Thomas3, M Musso4, D Hamer4, R Sheybani2, T Caffery3, C Alexander2, H Seng2, H Tse2
1Louisiana State University Health Sciences Center New Orleans, Pulmonary and Critical Care, Baton Rouge, United States; 2CytoVale, Inc., San Francisco, United States; 3Louisiana State University Health Sciences Center New Orleans, Baton Rouge, United States; 4Our Lady of the Lake Regional Medical Center, Baton Rouge, United States
P480 Midregional proadrenomedullin as a biomarker of microcirculatory and organ disfunction: prospective observational study
P Giaccaglia1, R Domizi2, J Montomoli2, C Scorcella3, A Carsetti3, E Damiani2, E Casarotta2, C D´Angelo2, S Bolognini2, A Donati2
1Marche Politechnic University, Anaesthesia and Intensive Care Unit, Ancona, Italy; 2Marche Politechnic University, Ancona, Italy; 3AOU Ospedali Riuniti, Ancona, Italy
P481 Clinical performance of a rapid sepsis test on a near-patient molecular testing platform
R Brandon1, J Kirk2, T Yager2, S Cermelli2, R Davis2, D Sampson2, P Sillekens3, I Keuleers3, T Vanhoey3
1Immunexpress, Seattle, United States; 2Immunexpress, Immunexpress, Seattle, United States; 3Biocartis NV, Biocartis, Mechelen, Belgium
P482 Accuracy of Septicyte™ for diagnosis of sepsis across a broad range of patients
R Brandon1, K Navalkar2, D Sampson2, R Davis2, T Yager2
1Immunexpress, Seattle, United States; 2Immunexpress, Immunexpress, Seattle, United States
# Datasets / Comparisons | # Case / Controls | Patients | Location | Mean AUC |
---|---|---|---|---|
13 / 35 | 1640 / 987 | Adults | ICU, Ward, ED | 0.88 |
2 / 4 | 177 / 513 | Adults / Pediatric | Ward | 0.85 |
7 / 16 | 417 / 589 | Pediatric / Neonates | ICU, Ward, ED | 0.87 |
Totals | ||||
22 / 55 | 2234 / 2089 | 0.87 |
P483 Open heart surgery interferes with vascular protective sphingosine-1-phosphate
G Greiwe1, M Winkler2
1University Medical Center Hamburg-Eppendorf, Department of Anesthesiology, Hamburg, Germany; 2University Medicine Göttingen, Department of Anesthesiology and Intensive Care Medicine, Göttingen, Germany
P484 Role of neutrophil CD64 (nCD64) and monocytic HLA-DR (mHLA-DR) as newer biomarkers of sepsis management in adult patients admitted in ICU
K Pandey1, SS Nath1, M Tripathi1, D Malviya1, M Harjai1, NP Awasthi2
1Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of Anesthesia and Critical Care, Lucknow, India; 2Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of Pathology, Lucknow, India
P485 AQP4 polymorphism in sepsis: a pilot study in ICU setting
VM Pisarev1, AG Chumachenko1, EK Grigoriev1, NA Karpun2
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A.Negovsky Institute of General Reanimatology, Moscow, Russia; 2V.P. Demikhov City Clinical Hospital, Moscow, Russia
P486 Validation of presepsin as a biomarker of sepsis in comparison to procalcitonin, IL-6 and IL-8
V Chantziara1, F Kaminari1, C Sklavou1, S Fortis2, P Kogionou2, S Perez2, A Efthymiou1
1Saint Savvas Hospital, ICU, Athens, Greece; 2Saint Savvas Hospital, Cancer Immunology and Immunotherapy Center, Athens, Greece
P487 Prospective validation of clinical sepsis phenotypes
K Demerle1, JN Kennedy1, OM Peck Palmer2, DC Angus1, CW Seymour1
1University of Pittsburgh, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Pittsburgh, United States; 2University of Pittsburgh, Division of Clinical Chemistry in the Section of Laboratory Medicine, Pittsburgh, United States
P488 HIPEC influences CRP kinetics?
A Ricardo1, J Silvestre1, N Abecassis2, R Marques1, N Candeias1, J Nunes1
1Hospital Lusiadas Lisboa, Intensive Care Unit, Lisboa, Portugal; 2Hospital Lusiadas Lisboa, Surgical department, Lisboa, Portugal
P489 Decreased thrombin generation potential is associated with increased thrombin generation markers in sepsis associated coagulopathy
D Hoppensteadt1, F Siddiqui1, E Bontekoe1, R Laddu1, R Matthew2, E Brailovsky3, J Fareed.1
1Loyola University Medical Center, Pathology, Maywood, United States; 2University of Utah, Cardiovascular Institute, Utah, United States; 3Loyola University Medical Center, Cardiovascular Institute, Maywood, United States
Parameters/Markers | Normal Plasma (n=50) | SAC Samples (n=49) |
---|---|---|
Peak Thrombin (nM) | 160 ± 10.78 | 82 ± 40 |
Lag Time (min) | 2.7 ± 0.20 | 4.1 ± 2.05 |
Area Under Curve (nM*min) | 700 ± 17.76 | 561 ± 283 |
F1.2 (pmol) | 570.0 ± 48 | 210 ± 25 |
TAT (ng/ml) | 27.9 ± 5.1 | 2.8 ± 0.8 |
AT (%) | 100 ± 20 | 64.0 ± 11 |
P490 Procalcitonin guided blood culture management in the intensive care unit
H Van leeuwen1, M Houterman2, R Bosboom2, D Hoogeveen2
1Rijnstate Ziekenhuis, ICU, Arnhem, Netherlands; 2Rijnstate Ziekenhuis, Arnhem, Netherlands
P491 Circulating plasma cell-free DNA and oxidized cell-free DNA as predictive biomarkers of sepsis in neuroresuscitation ICU patients
VM Pisarev1, AG Chumachenko1, EV Elisina1, SV Kostyuk2, ES Ershova2
1Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A.Negovsky Institute of General Reanimatology, Moscow, Russia; 2Research Centre for Medical Genetics, Moscow, Russia
P492 Heparin binding protein as an early diagnostic and prognostic tool in patients with suspected infection
A Safarika1, K Katsaros2, N Melachroinopoulos1, N Tsokos3, P Koutoukas4, EJ Giamarellos-Bourboulis5
1National and Kapodistrian University of Athens, Athens, Greece; 2Nafplion General Hospital, Nafplion, Greece; 3Halkida General Hospital, Halkida, Greece; 4Sparti General Hospital, Sparti, Greece, 5National and Kapodistrian University of Athens, 4th Department of Internal Medicine, Athens, Greece
P493 Chronobiological and recurrence quantification analysis of temperature rhythmicity in critically ill patients
V Papaioannou1, E Sertaridou1, I Chouvarda2, I Pneumatikos1
1University Hospital of Alexandroupolis, Intensive Care Unit, Alexandroupolis, Greece; 2Aristotle University of Thessaloniki, Faculty of Medicine, Laboratory of Computing, Medical Informatics and Biomedical Imaging Technologies, Thessaloniki, Greece
P494 Sex differences in the epidemiology and mortality of sepsis. The HUNT study
RM Mohus1, MK Moen2, T Rogne3, TI Nilsen4, BO Åsvold5, JK Damås6, LT Gustad7, E Solligård8
1Clinic of Anaesthesia and Intensive care, St. Olavs hospital, Trondheim, Norway; 2Clinic of Anaesthesia and Intensive care, St. Olavs hospital, Clinic of Anaesthesia and Intensive care, St. Olavs hospital, Trondheim, Norway; 3Department of Circulation and Medical Imaging, NTNU, Department of Circulation and Medical Imaging, NTNU, Trondheim, Trondheim, Norway; 4Department of Public Health and Nursing, NTNU, Departement of Public Health and Nursing, Trondheim, Norway; 5Department of Public Health and Nursing, NTNU, Department of public health and nursing., Trondheim, Norway; 6Department of Clincal and Molecular Medicine, NTNU, Department of Clincal and Molecular Medicine, Trondheim, Norway; 7Clinic of Internal Medicine and Rehabilitation, Levanger Hospital, Helse Nord-Trøndelag Hospital Trust, Clinic of Internal Medicine and Rehabilitation, Levanger Hospital, Helse Nord-Trøndelag Hospital Trust, Levanger, Norway; 8Department of Circulation and Medical Imaging, NTNU, Department of Circulation and Medical Imaging, Trondheim, Norway
P495 Incidence of hospital-acquired infection in sepsis patients – results from a retrospective cohort study
A Schettler1, M Spoden2, L Wedekind3, N Rose1, A Freytag4, P Schlattmann3, K Reinhart5, C Günster2, CS Hartog5, C Fleischmann-Struzek1
1Jena University Hospital, Center for Sepsis Control and Care, Jena, Germany; 2Wissenschaftliches Institut der AOK, Forschungsbereich Qualitaets- und Versorgungsforschung, Berlin, Germany; 3Jena University Hospital, Institute for Medical Statistics, Computer Science and Data Science, Jena, Germany; 4Jena University Hospital, Institute of General Practice and Family Medicine, Jena, Germany; 5Charité Universitätsmedizin, Department of Anesthesiology and Operative Intensive Care Medicine, Berlin, Germany
ICU-treated Sepsis (n=54,319) | Non-ICU- treated Sepsis (n=105,372) | ICU-treated Severe Sepsis (n=34,999) | Non-ICU-treated Severe Sepsis (n=29,993) | |
---|---|---|---|---|
Explicitly coded HAI, n, Among them: | 19,091 | 14,312 | 12,897 | 5,206 |
Nosocomial pneumonia, n, % | 10,300 (54%) | 4,758 (33%) | 7,380 (57%) | 2,091 (40%) |
Surgical site infection, n, % | 1,934 (10%) | 1,862 (13%) | 1,177 (9%) | 533 (10%) |
CLABSI, n, % | 3,960 (21%) | 2,033 (14%) | 2,565 (20%) | 613 (12%) |
CAUTI, n, % | 1,124 (6%) | 1,416 (10%) | 824 (6.4%) | 545 (10%) |
Clostridium difficile infection, n, % | 3,107 (16%) | 3,851 (27%) | 2,107 (16%) | 1,450 (28%) |
Other nosocomial infections, n, % | 3,825 (20%) | 1,904 (13%) | 2,478 (19%) | 638 (12%) |
P496 Impact of sepsis protocol triggered by Ramathibodi Early Warning Score (REWS) in IPD sepsis on clinical outcomes
S Matupumanon1, Y Sutherasan2, D Junhasawasdikul2, P Theerawit3
1Faculty of medicine Ramathibodi hospital, Department of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Faculty of medicine Ramathibodi hospital, Division of Pulmonary and Pulmonary Critical Care Medicine, Department of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 3Faculty of medicine Ramathibodi hospital, Division of Critical Care Medicine, Department of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Sepsis managements and outcomes | Pre-protocol n=141 | Post-protocol n=141 | P |
---|---|---|---|
Initial Laboratory measurement n(%) | 138(97.9) | 140(99.3) | 0.32 |
Initial lactate measurement n(%) | 46(32.6) | 90(63.8) | 0.00 |
Blood culture taking before antibioticsn(%) | 137(97.2) | 140(99.3) | 0.18 |
Time to antibiotics less than 1 hour(%) | 53(37.6) | 80(56.7) | 0.00 |
Fluid management n(%) | 22(15.6) | 51(36.2) | 0.00 |
ICU Length of stay,days, median (IQR) | 10.0 (5.0 – 20.5) | 8.0 (3.0 – 16.5) | 0.01 |
In-hospital mortality, n(%) | 51(36.2) | 44(31.2) | 0.39 |