Skip to main content
Erschienen in: European Radiology 7/2011

01.07.2011 | Chest

Low-dose triple-rule-out using 320-row-detector volume MDCT – less contrast medium and lower radiation exposure

verfasst von: Tahir Durmus, Patrik Rogalla, Alexander Lembcke, Matthias R. Mühler, Bernd Hamm, Patrick A. Hein

Erschienen in: European Radiology | Ausgabe 7/2011

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To investigate image quality of triple-rule-out (TRO) computed tomography (CT) using a 320-row-detector CT system with substantially reduced contrast medium volume at 100 kV.

Methods

Forty-six consecutive patients with noncritical, acute chest pain underwent 320-row-detector CT using a two-step TRO protocol consisting of a non-spiral, non-gated chest CT acquisition (150 mA) followed by a non-spiral, electrocardiography-gated cardiac acquisition (200–500 mA based on body mass index (BMI)). Data were acquired using a biphasic injection protocol with a total iodinated contrast medium volume of 60 ml (370 mg/ml). Vessel attenuation and effective doses were recorded. Image quality was scored independently by two readers.

Results

Mean attenuation was 584 ± 114 Hounsfield units (HU) in the ascending aorta, 335 ± 63HU in the aortic arch, 658 ± 136HU in the pulmonary trunk, and 521 ± 97HU and 549 ± 102HU in the right and left coronary artery, respectively. In all but one patient, attenuation and image quality allowed accurate visualization of the pulmonary arteries, thoracic aorta, and coronary arteries in a single examination. Ninety-six percent of all coronary artery segments were rated diagnostic. Radiation exposure ranged between 2.0 and 3.3 mSv.

Conclusion

Using 320-row-detector CT the investigated low-dose TRO protocol resulted in excellent opacification and image quality with substantial reduction of contrast medium volume compared to recently published TRO protocols.
Literatur
1.
Zurück zum Zitat Frauenfelder T, Appenzeller P, Karlo C, Scheffel H, Desbiolles L, Stolzmann P, Marincek B, Alkadhi H, Schertler T (2009) Triple rule-out CT in the emergency department: protocols and spectrum of imaging findings. Eur Radiol 19:789–799PubMedCrossRef Frauenfelder T, Appenzeller P, Karlo C, Scheffel H, Desbiolles L, Stolzmann P, Marincek B, Alkadhi H, Schertler T (2009) Triple rule-out CT in the emergency department: protocols and spectrum of imaging findings. Eur Radiol 19:789–799PubMedCrossRef
2.
Zurück zum Zitat Ladapo JA, Hoffmann U, Bamberg F, Nagurney JT, Cutler DM, Weinstein MC, Gazelle GS (2008) Cost-effectiveness of coronary MDCT in the triage of patients with acute chest pain. AJR Am J Roentgenol 191:455–463PubMedCrossRef Ladapo JA, Hoffmann U, Bamberg F, Nagurney JT, Cutler DM, Weinstein MC, Gazelle GS (2008) Cost-effectiveness of coronary MDCT in the triage of patients with acute chest pain. AJR Am J Roentgenol 191:455–463PubMedCrossRef
3.
Zurück zum Zitat Dewey M, Hamm B (2007) Cost effectiveness of coronary angiography and calcium scoring using CT and stress MRI for diagnosis of coronary artery disease. Eur Radiol 17:1301–1309PubMedCrossRef Dewey M, Hamm B (2007) Cost effectiveness of coronary angiography and calcium scoring using CT and stress MRI for diagnosis of coronary artery disease. Eur Radiol 17:1301–1309PubMedCrossRef
4.
Zurück zum Zitat Lell M, Hinkmann F, Anders K, Deak P, Kalender WA, Uder M, Achenbach S (2009) High-pitch electrocardiogram-triggered computed tomography of the chest: initial results. Invest Radiol 44:728–733PubMedCrossRef Lell M, Hinkmann F, Anders K, Deak P, Kalender WA, Uder M, Achenbach S (2009) High-pitch electrocardiogram-triggered computed tomography of the chest: initial results. Invest Radiol 44:728–733PubMedCrossRef
5.
Zurück zum Zitat Sommer WH, Schenzle JC, Becker CR, Nikolaou K, Graser A, Michalski G, Neumaier K, Reiser MF, Johnson TR (2009) Saving dose in triple-rule-out computed tomography examination using a high-pitch dual spiral technique. Invest Radiol 45:64–71CrossRef Sommer WH, Schenzle JC, Becker CR, Nikolaou K, Graser A, Michalski G, Neumaier K, Reiser MF, Johnson TR (2009) Saving dose in triple-rule-out computed tomography examination using a high-pitch dual spiral technique. Invest Radiol 45:64–71CrossRef
6.
Zurück zum Zitat Lee HY, Yoo SM, White CS (2009) Coronary CT angiography in emergency department patients with acute chest pain: triple rule-out protocol versus dedicated coronary CT angiography. Int J Cardiovasc Imaging 25:319–326PubMedCrossRef Lee HY, Yoo SM, White CS (2009) Coronary CT angiography in emergency department patients with acute chest pain: triple rule-out protocol versus dedicated coronary CT angiography. Int J Cardiovasc Imaging 25:319–326PubMedCrossRef
7.
Zurück zum Zitat Takakuwa KM, Halpern EJ, Gingold EL, Levin DC, Shofer FS (2009) Radiation dose in a “triple rule-out” coronary CT angiography protocol of emergency department patients using 64-MDCT: the impact of ECG-based tube current modulation on age, sex, and body mass index. AJR Am J Roentgenol 192:866–872PubMedCrossRef Takakuwa KM, Halpern EJ, Gingold EL, Levin DC, Shofer FS (2009) Radiation dose in a “triple rule-out” coronary CT angiography protocol of emergency department patients using 64-MDCT: the impact of ECG-based tube current modulation on age, sex, and body mass index. AJR Am J Roentgenol 192:866–872PubMedCrossRef
8.
Zurück zum Zitat Schertler T, Frauenfelder T, Stolzmann P, Scheffel H, Desbiolles L, Marincek B, Kaplan V, Kucher N, Alkadhi H (2009) Triple rule-out CT in patients with suspicion of acute pulmonary embolism: findings and accuracy. Acad Radiol 16:708–717PubMedCrossRef Schertler T, Frauenfelder T, Stolzmann P, Scheffel H, Desbiolles L, Marincek B, Kaplan V, Kucher N, Alkadhi H (2009) Triple rule-out CT in patients with suspicion of acute pulmonary embolism: findings and accuracy. Acad Radiol 16:708–717PubMedCrossRef
9.
Zurück zum Zitat Hein PA, Romano VC, Lembcke A, May J, Rogalla P (2009) Initial experience with a chest pain protocol using 320-slice volume MDCT. Eur Radiol 19:1148–1155PubMedCrossRef Hein PA, Romano VC, Lembcke A, May J, Rogalla P (2009) Initial experience with a chest pain protocol using 320-slice volume MDCT. Eur Radiol 19:1148–1155PubMedCrossRef
10.
Zurück zum Zitat Lembcke A, Wiese TH, Schnorr J, Wagner S, Mews J, Kroencke TJ, Enzweiler CN, Hamm B, Taupitz M (2004) Image quality of noninvasive coronary angiography using multislice spiral computed tomography and electron-beam computed tomography: intraindividual comparison in an animal model. Invest Radiol 39:357–364PubMedCrossRef Lembcke A, Wiese TH, Schnorr J, Wagner S, Mews J, Kroencke TJ, Enzweiler CN, Hamm B, Taupitz M (2004) Image quality of noninvasive coronary angiography using multislice spiral computed tomography and electron-beam computed tomography: intraindividual comparison in an animal model. Invest Radiol 39:357–364PubMedCrossRef
11.
Zurück zum Zitat Leschka S, Stolzmann P, Schmid FT, Scheffel H, Stinn B, Marincek B, Alkadhi H, Wildermuth S (2008) Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose. Eur Radiol 18:1809–1817PubMedCrossRef Leschka S, Stolzmann P, Schmid FT, Scheffel H, Stinn B, Marincek B, Alkadhi H, Wildermuth S (2008) Low kilovoltage cardiac dual-source CT: attenuation, noise, and radiation dose. Eur Radiol 18:1809–1817PubMedCrossRef
12.
Zurück zum Zitat Bongartz G, Golding SJ, Jurik AG, Leonardi M, van Persijn van Meerten E, Rodríguez R, Schneider K, Calzado A, Geleijns J, Jessen KA, Panzer W, Shrimpton PC, Tosi G (2004) European Guidelines for Multislice Computed Tomography. Funded by the European Commission. Appendix C; Available via http://www.msct.eu/CT_Quality_Criteria.htm. Accessed February 9, 2011 Bongartz G, Golding SJ, Jurik AG, Leonardi M, van Persijn van Meerten E, Rodríguez R, Schneider K, Calzado A, Geleijns J, Jessen KA, Panzer W, Shrimpton PC, Tosi G (2004) European Guidelines for Multislice Computed Tomography. Funded by the European Commission. Appendix C; Available via http://​www.​msct.​eu/​CT_​Quality_​Criteria.​htm. Accessed February 9, 2011
13.
Zurück zum Zitat Hendel RC (2009) Is computed tomography coronary angiography the most accurate and effective noninvasive imaging tool to evaluate patients with acute chest pain in the emergency department? CT coronary angiography is the most accurate and effective noninvasive imaging tool for evaluating patients presenting with chest pain to the emergency department: antagonist viewpoint. Circ Cardiovasc Imaging 2:264–275, discussion 275PubMedCrossRef Hendel RC (2009) Is computed tomography coronary angiography the most accurate and effective noninvasive imaging tool to evaluate patients with acute chest pain in the emergency department? CT coronary angiography is the most accurate and effective noninvasive imaging tool for evaluating patients presenting with chest pain to the emergency department: antagonist viewpoint. Circ Cardiovasc Imaging 2:264–275, discussion 275PubMedCrossRef
14.
Zurück zum Zitat Achenbach S, Daniel WG (2010) Cardiac imaging in the patient with chest pain: coronary CT angiography. Heart 96:1241–1246PubMedCrossRef Achenbach S, Daniel WG (2010) Cardiac imaging in the patient with chest pain: coronary CT angiography. Heart 96:1241–1246PubMedCrossRef
15.
Zurück zum Zitat Halpern EJ (2009) Triple-rule-out CT angiography for evaluation of acute chest pain and possible acute coronary syndrome. Radiology 252:332–345PubMedCrossRef Halpern EJ (2009) Triple-rule-out CT angiography for evaluation of acute chest pain and possible acute coronary syndrome. Radiology 252:332–345PubMedCrossRef
16.
Zurück zum Zitat McMahon MA, Squirrell CA (2010) Multidetector CT of aortic dissection: a pictorial review. Radiographics 30:445–460PubMedCrossRef McMahon MA, Squirrell CA (2010) Multidetector CT of aortic dissection: a pictorial review. Radiographics 30:445–460PubMedCrossRef
17.
Zurück zum Zitat Murayama T, Funabashi N, Uehara M, Takaoka H, Komuro I (2010) New classification of aortic dissection during the cardiac cycle as pulsating type and static type evaluated by electrocardiogram-gated multislice CT. Int J Cardiol 142:177–186PubMedCrossRef Murayama T, Funabashi N, Uehara M, Takaoka H, Komuro I (2010) New classification of aortic dissection during the cardiac cycle as pulsating type and static type evaluated by electrocardiogram-gated multislice CT. Int J Cardiol 142:177–186PubMedCrossRef
18.
Zurück zum Zitat Ganten MK, Weber TF, von Tengg-Kobligk H, Bockler D, Stiller W, Geisbusch P, Kauffmann GW, Delorme S, Bock M, Kauczor HU (2009) Motion characterization of aortic wall and intimal flap by ECG-gated CT in patients with chronic B-dissection. Eur J Radiol 72:146–153PubMedCrossRef Ganten MK, Weber TF, von Tengg-Kobligk H, Bockler D, Stiller W, Geisbusch P, Kauffmann GW, Delorme S, Bock M, Kauczor HU (2009) Motion characterization of aortic wall and intimal flap by ECG-gated CT in patients with chronic B-dissection. Eur J Radiol 72:146–153PubMedCrossRef
19.
Zurück zum Zitat Matsuoka S, Hunsaker AR, Gill RR, Oliva IB, Trotman-Dickenson B, Jacobson FL, Hatabu H (2009) Vascular enhancement and image quality of MDCT pulmonary angiography in 400 cases: comparison of standard and low kilovoltage settings. AJR Am J Roentgenol 192:1651–1656PubMedCrossRef Matsuoka S, Hunsaker AR, Gill RR, Oliva IB, Trotman-Dickenson B, Jacobson FL, Hatabu H (2009) Vascular enhancement and image quality of MDCT pulmonary angiography in 400 cases: comparison of standard and low kilovoltage settings. AJR Am J Roentgenol 192:1651–1656PubMedCrossRef
20.
Zurück zum Zitat Szucs-Farkas Z, Strautz T, Patak MA, Kurmann L, Vock P, Schindera ST (2009) Is body weight the most appropriate criterion to select patients eligible for low-dose pulmonary CT angiography? Analysis of objective and subjective image quality at 80 kVp in 100 patients. Eur Radiol 19:1914–1922PubMedCrossRef Szucs-Farkas Z, Strautz T, Patak MA, Kurmann L, Vock P, Schindera ST (2009) Is body weight the most appropriate criterion to select patients eligible for low-dose pulmonary CT angiography? Analysis of objective and subjective image quality at 80 kVp in 100 patients. Eur Radiol 19:1914–1922PubMedCrossRef
21.
Zurück zum Zitat Alkadhi H, Stolzmann P, Desbiolles L, Baumueller S, Goetti R, Plass A, Scheffel H, Feuchtner G, Falk V, Marincek B, Leschka S (2010) Low-dose, 128-slice, dual-source CT coronary angiography: accuracy and radiation dose of the high-pitch and the step-and-shoot mode. Heart 96:933–938PubMedCrossRef Alkadhi H, Stolzmann P, Desbiolles L, Baumueller S, Goetti R, Plass A, Scheffel H, Feuchtner G, Falk V, Marincek B, Leschka S (2010) Low-dose, 128-slice, dual-source CT coronary angiography: accuracy and radiation dose of the high-pitch and the step-and-shoot mode. Heart 96:933–938PubMedCrossRef
22.
Zurück zum Zitat Leschka S, Stolzmann P, Desbiolles L, Baumueller S, Goetti R, Schertler T, Scheffel H, Plass A, Falk V, Feuchtner G, Marincek B, Alkadhi H (2009) Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience. Eur Radiol 19:2896–2903PubMedCrossRef Leschka S, Stolzmann P, Desbiolles L, Baumueller S, Goetti R, Schertler T, Scheffel H, Plass A, Falk V, Feuchtner G, Marincek B, Alkadhi H (2009) Diagnostic accuracy of high-pitch dual-source CT for the assessment of coronary stenoses: first experience. Eur Radiol 19:2896–2903PubMedCrossRef
23.
Zurück zum Zitat Johnson TR, Nikolaou K, Becker A, Leber AW, Rist C, Wintersperger BJ, Reiser MF, Becker CR (2008) Dual-source CT for chest pain assessment. Eur Radiol 18:773–780PubMedCrossRef Johnson TR, Nikolaou K, Becker A, Leber AW, Rist C, Wintersperger BJ, Reiser MF, Becker CR (2008) Dual-source CT for chest pain assessment. Eur Radiol 18:773–780PubMedCrossRef
24.
Zurück zum Zitat Schertler T, Scheffel H, Frauenfelder T, Desbiolles L, Leschka S, Stolzmann P, Seifert B, Flohr TG, Marincek B, Alkadhi H (2007) Dual-source computed tomography in patients with acute chest pain: feasibility and image quality. Eur Radiol 17:3179–3188PubMedCrossRef Schertler T, Scheffel H, Frauenfelder T, Desbiolles L, Leschka S, Stolzmann P, Seifert B, Flohr TG, Marincek B, Alkadhi H (2007) Dual-source computed tomography in patients with acute chest pain: feasibility and image quality. Eur Radiol 17:3179–3188PubMedCrossRef
25.
Zurück zum Zitat Hein PA, May J, Rogalla P, Butler C, Hamm B, Lembcke A (2010) Feasibility of contrast material volume reduction in coronary artery imaging using 320-slice volume CT. Eur Radiol 20:1337–1343PubMedCrossRef Hein PA, May J, Rogalla P, Butler C, Hamm B, Lembcke A (2010) Feasibility of contrast material volume reduction in coronary artery imaging using 320-slice volume CT. Eur Radiol 20:1337–1343PubMedCrossRef
26.
Zurück zum Zitat Goetti R, Feuchtner G, Stolzmann P, Desbiolles L, Fischer MA, Karlo C, Baumueller S, Scheffel H, Alkadhi H, Leschka S (2010) High-pitch dual-source CT coronary angiography: systolic data acquisition at high heart rates. Eur Radiol 20:2565–2571PubMedCrossRef Goetti R, Feuchtner G, Stolzmann P, Desbiolles L, Fischer MA, Karlo C, Baumueller S, Scheffel H, Alkadhi H, Leschka S (2010) High-pitch dual-source CT coronary angiography: systolic data acquisition at high heart rates. Eur Radiol 20:2565–2571PubMedCrossRef
Metadaten
Titel
Low-dose triple-rule-out using 320-row-detector volume MDCT – less contrast medium and lower radiation exposure
verfasst von
Tahir Durmus
Patrik Rogalla
Alexander Lembcke
Matthias R. Mühler
Bernd Hamm
Patrick A. Hein
Publikationsdatum
01.07.2011
Verlag
Springer-Verlag
Erschienen in
European Radiology / Ausgabe 7/2011
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-011-2088-4

Weitere Artikel der Ausgabe 7/2011

European Radiology 7/2011 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.