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Brain Structure and Function

Erschienen in:

01.09.2003 | Original Article

Midbrain connections of the olivary pretectal nucleus in the marmoset (Callithrix jacchus): implications for the pupil light reflex pathway

verfasst von: Robert J. Clarke, Robert H. I. Blanks, Roland A. Giolli

Erschienen in: Brain Structure and Function | Ausgabe 2/2003

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Abstract

Midbrain projections of the pretectal olivary nucleus (PON) were studied in the marmoset, a New World primate. The fluorescent retrograde tracers Fluoro-Gold (FG) and Fast Blue (FB) were injected into the Edinger-Westphal (EW) nucleus and the lateral terminal nucleus (LTN), respectively. EW nucleus injections resulted in retrograde labeling of significant numbers of FG-positive neurons of the PON as well as a small number of cells in the LTN. LTN injections led to labeling of a population of singly-labeled cells seen dispersed through the larger population of FG-labeled somata within the contralateral PON. The ipsilateral PON was devoid of FB-labeled somata, whereas the adjacent nucleus of the optic tract (NOT) contained FB-labeled cells. These findings show that a large number of PON neurons project directly to the oculomotor complex. Additionally, the study shows the presence of a separate population of PON neurons projecting to the contralateral LTN. This, combined with our earlier observation that LTN neurons project to the EW nucleus in the marmoset (see main text for reference), lends support to the presence of separate direct and indirect pupillary light reflex pathways from the PON to the nucleus of EW.

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Titel: Midbrain connections of the olivary pretectal nucleus in the marmoset (Callithrix jacchus): implications for the pupil light reflex pathway
verfasst von: Robert J. Clarke
Robert H. I. Blanks
Roland A. Giolli
Publikationsdatum: 01.09.2003
Verlag: Springer-Verlag
Erschienen in: Brain Structure and Function / Ausgabe 2/2003
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-003-0339-0

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