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Erschienen in: Monatsschrift Kinderheilkunde 6/2003

01.06.2003 | Originalien

Spezifische Immuntherapien zur Behandlung von Krebs im Kindesalter

verfasst von: C. Rössig, D. Dilloo, H. Jürgens

Erschienen in: Monatsschrift Kinderheilkunde | Ausgabe 6/2003

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Zusammenfassung

Immuntherapie.

Die Immuntherapie bösartiger Tumoren beruht auf dem Konzept, durch gezielte Verstärkung tumorspezifischer Immunantworten eine Abstoßung der Tumorzellen herbeizuführen. Dazu kann entweder durch aktive Immunisierung eine tumorspezifische Aktivierung des Immunsystems induziert oder es können Effektoren des Immunsystems, wie Antikörper oder ex vivo expandierte zytotoxische T-Zellen, passiv verabreicht werden.

Einsatz in der Pädiatrie.

Der gezielte Einsatz immunologischer Therapiemodalitäten könnte eine sinnvolle Ergänzung zur Standardtherapie vieler pädiatrischer Tumoren darstellen. In dieser Übersicht werden aktuelle Konzepte zu den Mechanismen der Antitumorimmunität und ihrer Beeinflussung durch therapeutische Maßnahmen vorgestellt und der Stellenwert der Immuntherapie in der pädiatrischen Onkologie diskutiert.
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Metadaten
Titel
Spezifische Immuntherapien zur Behandlung von Krebs im Kindesalter
verfasst von
C. Rössig
D. Dilloo
H. Jürgens
Publikationsdatum
01.06.2003
Verlag
Springer Berlin Heidelberg
Erschienen in
Monatsschrift Kinderheilkunde / Ausgabe 6/2003
Print ISSN: 0026-9298
Elektronische ISSN: 1433-0474
DOI
https://doi.org/10.1007/s00112-002-0530-z

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