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BMC Medicine

Ausgabe 1/2014

Inhalt (235 Artikel)

Open Access Research article

Whole home exercise intervention for depression in older care home residents (the OPERA study): a process evaluation

David R Ellard, Margaret Thorogood, Martin Underwood, Clive Seale, Stephanie JC Taylor

Open Access Editorial

BMC Medicine: a decade of open access medical research

Sabina Alam, Jigisha Patel

Open Access Research article

Using verbal autopsy to measure causes of death: the comparative performance of existing methods

Christopher JL Murray, Rafael Lozano, Abraham D Flaxman, Peter Serina, David Phillips, Andrea Stewart, Spencer L James, Alireza Vahdatpour, Charles Atkinson, Michael K Freeman, Summer Lockett Ohno, Robert Black, Said Mohammed Ali, Abdullah H Baqui, Lalit Dandona, Emily Dantzer, Gary L Darmstadt, Vinita Das, Usha Dhingra, Arup Dutta, Wafaie Fawzi, Sara Gómez, Bernardo Hernández, Rohina Joshi, Henry D Kalter, Aarti Kumar, Vishwajeet Kumar, Marilla Lucero, Saurabh Mehta, Bruce Neal, Devarsetty Praveen, Zul Premji, Dolores Ramírez-Villalobos, Hazel Remolador, Ian Riley, Minerva Romero, Mwanaidi Said, Diozele Sanvictores, Sunil Sazawal, Veronica Tallo, Alan D Lopez

Open Access Opinion

Integrated care as a means to improve primary care delivery for adults and adolescents in the developing world: a critical analysis of Integrated Management of Adolescent and Adult Illness (IMAI)

Ashwin Vasan, Andrew Ellner, Stephen D Lawn, Sandy Gove, Manzi Anatole, Neil Gupta, Peter Drobac, Tom Nicholson, Kwonjune Seung, David C Mabey, Paul E Farmer

Open Access Reviewer acknowledgement

Reviewer acknowledgements for 2013

Sabina Alam

Open Access Question and Answer

BMC medicine editorial board members on open access publishing

Michael R Carmont, Stephen D Lawn, Babill Stray-Pedersen, Yehuda Shoenfeld, Pascal Meier

Open Access Research article

Spousal diabetes as a diabetes risk factor: A systematic review and meta-analysis

Aaron Leong, Elham Rahme, Kaberi Dasgupta

Open Access Commentary

Unexpected plateauing of childhood obesity rates in developed countries

Martin Wabitsch, Anja Moss, Katrin Kromeyer-Hauschild

Open Access Research article

Interaction between stress and the BDNFVal66Met polymorphism in depression: a systematic review and meta-analysis

Georgina M Hosang, Celia Shiles, Katherine E Tansey, Peter McGuffin, Rudolf Uher

Open Access Research article

Global collaborative networks on meta-analyses of randomized trials published in high impact factor medical journals: a social network analysis

Ferrán Catalá-López, Adolfo Alonso-Arroyo, Brian Hutton, Rafael Aleixandre-Benavent, David Moher

Open Access Commentary

Prospects for automated diagnosis of verbal autopsies

Michel Garenne

Open Access Research article

Performance of four computer-coded verbal autopsy methods for cause of death assignment compared with physician coding on 24,000 deaths in low- and middle-income countries

Nikita Desai, Lukasz Aleksandrowicz, Pierre Miasnikof, Ying Lu, Jordana Leitao, Peter Byass, Stephen Tollman, Paul Mee, Dewan Alam, Suresh Kumar Rathi, Abhishek Singh, Rajesh Kumar, Faujdar Ram, Prabhat Jha

Open Access Research article

Performance criteria for verbal autopsy-based systems to estimate national causes of death: development and application to the Indian Million Death Study

Lukasz Aleksandrowicz, Varun Malhotra, Rajesh Dikshit, Prakash C Gupta, Rajesh Kumar, Jay Sheth, Suresh Kumar Rathi, Wilson Suraweera, Pierre Miasnikof, Raju Jotkar, Dhirendra Sinha, Shally Awasthi, Prakash Bhatia, Prabhat Jha

Open Access Research article

Comparison of physician-certified verbal autopsy with computer-coded verbal autopsy for cause of death assignment in hospitalized patients in low- and middle-income countries: systematic review

Jordana Leitao, Nikita Desai, Lukasz Aleksandrowicz, Peter Byass, Pierre Miasnikof, Stephen Tollman, Dewan Alam, Ying Lu, Suresh Kumar Rathi, Abhishek Singh, Wilson Suraweera, Faujdar Ram, Prabhat Jha

Open Access Comment

Comment: Head and Neck Oncology

Open Access Commentary

Early start and stop of biologics: has the time come?

Ronald F van Vollenhoven, György Nagy, Paul P Tak

Open Access Research article

Selective intra-arterial infusion of rAd-p53 with chemotherapy for advanced oral cancer: a randomized clinical trial

Yi Li, Long-Jiang Li, Li-Juan Wang, Zhuang Zhang, Ning Gao, Chen-Yuan Liang, Yuan-Ding Huang, Bo Han

Open Access Research article

Empirical estimates of prostate cancer overdiagnosis by age and prostate-specific antigen

Andrew J Vickers, Daniel D Sjoberg, David Ulmert, Emily Vertosick, Monique J Roobol, Ian Thompson, Eveline AM Heijnsdijk, Harry De Koning, Coral Atoria-Swartz, Peter T Scardino, Hans Lilja

Open Access Research article

Drugs affecting the renin-angiotensin system and survival from cancer: a population based study of breast, colorectal and prostate cancer patient cohorts

Chris R Cardwell, Úna C Mc Menamin, Blánaid M Hicks, Carmel Hughes, Marie M Cantwell, Liam J Murray

Open Access Commentary

In-/off-label use of biologic therapy in systemic lupus erythematosus

Mariele Gatto, Emese Kiss, Yaakov Naparstek, Andrea Doria

Open Access Commentary

Do smartphone applications in healthcare require a governance and legal framework? It depends on the application!

Esmita Charani, Enrique Castro-Sánchez, Luke SP Moore, Alison Holmes

Open Access Review

Early life programming as a target for prevention of child and adolescent mental disorders

Andrew James Lewis, Megan Galbally, Tara Gannon, Christos Symeonides

Open Access Commentary

Epigenetics in the pathogenesis of rheumatoid arthritis

Tibor T Glant, Katalin Mikecz, Tibor A Rauch

Open Access Forum

Personalized medicine: risk prediction, targeted therapies and mobile health technology

Daniel F Hayes, Hugh S Markus, R David Leslie, Eric J Topol

Open Access Commentary

Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations

Pier Luigi Meroni, Nicola Bizzaro, Ilaria Cavazzana, Maria Orietta Borghi, Angela Tincani

Open Access Research article

Autoantibodies against MHC class I polypeptide-related sequence A are associated with increased risk of concomitant autoimmune diseases in celiac patients

Antonio López-Vázquez, Lourdes Mozo, Rebeca Alonso-Arias, Beatriz Suárez-Álvarez, José Ramón Vidal-Castiñeira, Eduardo Arranz, Umberto Volta, Carlos Bousoño, Marcos López-Hoyos, Luís Rodrigo, Carlos López-Larrea

Open Access Opinion

The intergenerational effects of war on the health of children

Delan Devakumar, Marion Birch, David Osrin, Egbert Sondorp, Jonathan CK Wells

Open Access Research article

The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients

Gijs Van Pottelbergh, Bert Vaes, Wim Adriaensen, Cathy Matheï, Delphine Legrand, Pierre Wallemacq, Jean Marie Degryse

Open Access Research article

Step counter use in type 2 diabetes: a meta-analysis of randomized controlled trials

Shanhu Qiu, Xue Cai, Xiang Chen, Bingquan Yang, Zilin Sun

Open Access Debate

What is the future of targeted therapy in rheumatology: biologics or small molecules?

Attila Mócsai, László Kovács, Péter Gergely

Open Access Question and Answer

Global mental health: an interview with Vikram Patel

Vikram Patel

Open Access Research article

Hospital admissions in relation to body mass index in UK women: a prospective cohort study

Gillian K Reeves, Angela Balkwill, Benjamin J Cairns, Jane Green, Valerie Beral

Open Access Commentary

The impact of excess body weight at the hospital frontline

Andrew G Renehan, Iain E Buchan

Open Access Research article

Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis

Ana Filipa Macedo, Fiona Claire Taylor, Juan P Casas, Alma Adler, David Prieto-Merino, Shah Ebrahim

Open Access Research article

Risk of ischemic stroke in patients with ovarian cancer: a nationwide population-based study

Ai-Seon Kuan, Chung-Jen Teng, Hua-Hsi Wu, Vincent Yi-Fong Su, Yung-Tai Chen, Sheng-Hsuan Chien, Chiu-Mei Yeh, Li-Yu Hu, Tzeng-Ji Chen, Cheng-Hwai Tzeng, Chia-Jen Liu

Open Access Research article

Effect of aspirin and other non-steroidal anti-inflammatory drugs on prostate cancer incidence and mortality: a systematic review and meta-analysis

Yanqiong Liu, Jun-Qiang Chen, Li Xie, Jian Wang, Taijie Li, Yu He, Yong Gao, Xue Qin, Shan Li

Open Access Research article

School-based mental health intervention for children in war-affected Burundi: a cluster randomized trial

Wietse A Tol, Ivan H Komproe, Mark JD Jordans, Aline Ndayisaba, Prudence Ntamutumba, Heather Sipsma, Eva S Smallegange, Robert D Macy, Joop TVM de Jong

Open Access Commentary

Is atherosclerosis an autoimmune disease?

Eiji Matsuura, Fabiola Atzeni, Piercarlo Sarzi-Puttini, Maurizio Turiel, Luis R Lopez, Michael T Nurmohamed

Open Access Commentary

Biologics, cardiovascular effects and cancer

Nemanja Damjanov, Michael T Nurmohamed, Zoltán Szekanecz

Open Access Commentary

Laboratory biomarkers or imaging in the diagnostics of rheumatoid arthritis?

Ladislav Šenolt, Walter Grassi, Peter Szodoray

Open Access Commentary

Risks and benefits of transfusion for children with severe anemia in Africa

Thomas Brick, Mark J Peters

Open Access Research article

Formal and informal prediction of recurrent stroke and myocardial infarction after stroke: a systematic review and evaluation of clinical prediction models in a new cohort

Douglas D Thompson, Gordon D Murray, Martin Dennis, Cathie LM Sudlow, William N Whiteley

Open Access Research article

Effectiveness of dietary interventions among adults of retirement age: a systematic review and meta-analysis of randomized controlled trials

Jose Lara, Nicola Hobbs, Paula J Moynihan, Thomas D Meyer, Ashley J Adamson, Linda Errington, Lynn Rochester, Falko F Sniehotta, Martin White, John C Mathers

Open Access Research article

Obesity survival paradox in pneumonia: a meta-analysis

Wei Nie, Yi Zhang, Sun Ha Jee, Keum Ji Jung, Bing Li, Qingyu Xiu

Open Access Research article

The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial)

Leiv Otto Watne, Anne Cathrine Torbergsen, Simon Conroy, Knut Engedal, Frede Frihagen, Geir Aasmund Hjorthaug, Vibeke Juliebo, Johan Raeder, Ingvild Saltvedt, Eva Skovlund, Torgeir Bruun Wyller

Open Access Research article

Preventing the development of depression at work: a systematic review and meta-analysis of universal interventions in the workplace

Leona Tan, Min-Jung Wang, Matthew Modini, Sadhbh Joyce, Arnstein Mykletun, Helen Christensen, Samuel B Harvey

Open Access Editorial

Prevention of mental disorders: evidence, challenges and opportunities

Felice N Jacka, Nicola J Reavley

Open Access Research article

Lifestyle risk factors and residual life expectancy at age 40: a German cohort study

Kuanrong Li, Anika Hüsing, Rudolf Kaaks

Open Access Research article

Muscle strength in adolescent men and risk of cardiovascular disease events and mortality in middle age: a prospective cohort study

Simon Timpka, Ingemar F Petersson, Caddie Zhou, Martin Englund

Open Access Research article

Verbal autopsy as a tool for identifying children dying of sickle cell disease: a validation study conducted in Kilifi district, Kenya

Carolyne Ndila, Evasius Bauni, Vysaul Nyirongo, George Mochamah, Alex Makazi, Patrick Kosgei, Gideon Nyutu, Alex Macharia, Sailoki Kapesa, Peter Byass, Thomas N Williams

Open Access Research article

Predictive score for mortality in patients with COPD exacerbations attending hospital emergency departments

José M Quintana, Cristóbal Esteban, Anette Unzurrunzaga, Susana Garcia-Gutierrez, Nerea Gonzalez, Irantzu Barrio, Inmaculada Arostegui, Iratxe Lafuente, Marisa Bare, Nerea Fernandez-de-Larrea, Silvia Vidal

Open Access Research article

Polyphenol intake and mortality risk: a re-analysis of the PREDIMED trial

Anna Tresserra-Rimbau, Eric B Rimm, Alexander Medina-Remón, Miguel A Martínez-González, M Carmen López-Sabater, María I Covas, Dolores Corella, Jordi Salas-Salvadó, Enrique Gómez-Gracia, José Lapetra, Fernando Arós, Miquel Fiol, Emili Ros, Lluis Serra-Majem, Xavier Pintó, Miguel A Muñoz, Alfredo Gea, Valentina Ruiz-Gutiérrez, Ramón Estruch, Rosa M Lamuela-Raventós

Open Access Research article

Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia

Peter Olupot-Olupot, Charles Engoru, Jennifer Thompson, Julius Nteziyaremye, Martin Chebet, Tonny Ssenyondo, Cornelius M Dambisya, Vicent Okuuny, Ronald Wokulira, Denis Amorut, Paul Ongodia, Ayub Mpoya, Thomas N Williams, Sophie Uyoga, Alex Macharia, Diana M Gibb, A Sarah Walker, Kathryn Maitland

Open Access Research article

A meta-analysis of sublingual allergen immunotherapy and pharmacotherapy in pollen-induced seasonal allergic rhinoconjunctivitis

Philippe Devillier, Jean-François Dreyfus, Pascal Demoly, Moisés A Calderón

Open Access Commentary

suPAR and Team Nephrology

Howard Trachtman

Open Access Debate

The ‘placement’ of people with profound impairments across the lifespan: re-thinking age criteria

Barbara E Gibson, Gillian King, Shauna Kingsnorth, Patricia McKeever

Open Access Research article

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

Marta Guasch-Ferré, Frank B Hu, Miguel A Martínez-González, Montserrat Fitó, Mònica Bulló, Ramon Estruch, Emilio Ros, Dolores Corella, Javier Recondo, Enrique Gómez-Gracia, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Miguel A Muñoz, Xavier Pintó, Rosa M Lamuela-Raventós, Josep Basora, Pilar Buil-Cosiales, José V Sorlí, Valentina Ruiz-Gutiérrez, J Alfredo Martínez, Jordi Salas-Salvadó

Open Access Commentary

Non-celiac gluten sensitivity - why worry?

Knut E A Lundin

Open Access Research article

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

Anna Edlund, Jonathan LS Esguerra, Anna Wendt, Malin Flodström-Tullberg, Lena Eliasson

Open Access Opinion

Towards the clinical implementation of pharmacogenetics in bipolar disorder

Naji C Salloum, Michael J McCarthy, Susan G Leckband, John R Kelsoe

Open Access Research article

The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder

Karim Malki, Robert Keers, Maria Grazia Tosto, Anbarasu Lourdusamy, Lucia Carboni, Enrico Domenici, Rudolf Uher, Peter McGuffin, Leonard C Schalkwyk

Open Access Research article

Additive effects of blood glucose lowering drugs, statins and renin-angiotensin system blockers on all-site cancer risk in patients with type 2 diabetes

Alice PS Kong, Xilin Yang, Wing-Yee So, Andrea Luk, Ronald CW Ma, Risa Ozaki, Kitty KT Cheung, Heung-Man Lee, Linda Yu, Gang Xu, Chun-Chung Chow, Juliana CN Chan

Open Access Research article

Risk stratification in emergency patients by copeptin

Kasper Iversen, Jens P Gøtze, Morten Dalsgaard, Henrik Nielsen, Søren Boesgaard, Morten Bay, Vibeke Kirk, Olav W Nielsen, Lars Køber

Open Access Research article

An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity

Umberto Volta, Maria Teresa Bardella, Antonino Calabrò, Riccardo Troncone, Gino Roberto Corazza

Open Access Research article

Are weekend inpatient rehabilitation services value for money? An economic evaluation alongside a randomized controlled trial with a 30 day follow up

Natasha Kareem Brusco, Jennifer J Watts, Nora Shields, Nicholas F Taylor

Open Access Minireview

Dark matter RNA illuminates the puzzle of genome-wide association studies

Georges St. Laurent, Yuri Vyatkin, Philipp Kapranov

Open Access Commentary

Achieving a polio free world

Mohammad Ali, David A Sack

Open Access Research article

A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

Michael T White, Philip Bejon, Ally Olotu, Jamie T Griffin, Kalifa Bojang, John Lusingu, Nahya Salim, Salim Abdulla, Nekoye Otsyula, Selidji T Agnandji, Bertrand Lell, Kwaku Poku Asante, Seth Owusu-Agyei, Emmanuel Mahama, Tsiri Agbenyega, Daniel Ansong, Jahit Sacarlal, John J Aponte, Azra C Ghani

Open Access Research article

The epidemiology of silent brain infarction: a systematic review of population-based cohorts

Jonathon P Fanning, Andrew A Wong, John F Fraser

Open Access Editorial

The ethics and editorial challenges of internet-based research

Stephanie Harriman, Jigisha Patel

Open Access Research article

The association between the ratio of monocytes:lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life

Vivek Naranbhai, Soyeon Kim, Helen Fletcher, Mark F Cotton, Avy Violari, Charles Mitchell, Sharon Nachman, George McSherry, Helen McShane, Adrian VS Hill, Shabir A Madhi

Open Access Research article

Hypertension, kidney disease, HIV and antiretroviral therapy among Tanzanian adults: a cross-sectional study

Robert N Peck, Rehema Shedafa, Samuel Kalluvya, Jennifer A Downs, Jim Todd, Manikkam Suthanthiran, Daniel W Fitzgerald, Johannes B Kataraihya

Open Access Research article

Findings from the SASA! Study: a cluster randomized controlled trial to assess the impact of a community mobilization intervention to prevent violence against women and reduce HIV risk in Kampala, Uganda

Tanya Abramsky, Karen Devries, Ligia Kiss, Janet Nakuti, Nambusi Kyegombe, Elizabeth Starmann, Bonnie Cundill, Leilani Francisco, Dan Kaye, Tina Musuya, Lori Michau, Charlotte Watts

Open Access Commentary

Atypical antipsychotic agents; Peas in a pod or chalk and cheese?

Ajeet B Singh, Andrew A Nierenberg, Lakshmi N Yatham, Michael Berk

Open Access Research article

A clinical prediction rule for diagnosing human infections with avian influenza A(H7N9) in a hospital emergency department setting

Qiaohong Liao, Dennis K M Ip, Tim K Tsang, Bin Cao, Hui Jiang, Fengfeng Liu, Jiandong Zheng, Zhibin Peng, Peng Wu, Yang Huai, Eric H Y Lau, Luzhao Feng, Gabriel M Leung, Hongjie Yu, Benjamin J Cowling

Open Access Research article

Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes

Youli Yao, Alexandra M Robinson, Fabiola CR Zucchi, Jerrah C Robbins, Olena Babenko, Olga Kovalchuk, Igor Kovalchuk, David M Olson, Gerlinde AS Metz

Open Access Commentary

The hunt for protective correlates of immunity to Plasmodium falciparummalaria

Ann M Moormann, V Ann Stewart

Open Access Forum

Next generation sequencing and tumor mutation profiling: are we ready for routine use in the oncology clinic?

Debu Tripathy, Kathleen Harnden, Kimberly Blackwell, Mark Robson

Open Access Research article

Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction: a pilot randomized controlled trial

Kelsey DJ Jones, Barbara Hünten-Kirsch, Ahmed MR Laving, Caroline W Munyi, Moses Ngari, Jenifer Mikusa, Musa M Mulongo, Dennis Odera, H Samira Nassir, Molline Timbwa, Moses Owino, Greg Fegan, Simon H Murch, Peter B Sullivan, John O Warner, James A Berkley

Open Access Editorial

Text recycling: acceptable or misconduct?

Stephanie Harriman, Jigisha Patel

Open Access Research article

Burden of mental disorders and unmet needs among street homeless people in Addis Ababa, Ethiopia

Abebaw Fekadu, Charlotte Hanlon, Emebet Gebre-Eyesus, Melkamu Agedew, Haddis Solomon, Solomon Teferra, Tsehaysina Gebre-Eyesus, Yonas Baheretibeb, Girmay Medhin, Teshome Shibre, Abraham Workneh, Teketel Tegegn, Alehegn Ketema, Philip Timms, Graham Thornicroft, Martin Prince

Open Access Research article

Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: a meta-analysis

Nienke Langebeek, Elizabeth H Gisolf, Peter Reiss, Sigrid C Vervoort, Thóra B Hafsteinsdóttir, Clemens Richter, Mirjam AG Sprangers, Pythia T Nieuwkerk

Open Access Opinion

Type 2 diabetes as a disease of ectopic fat?

Naveed Sattar, Jason MR Gill

Open Access Question and Answer

Obesity and what we need do about it- an interview with John Wass

John Wass

Open Access Research article

Novel equation to determine the hepatic triglyceride concentration in humans by MRI: diagnosis and monitoring of NAFLD in obese patients before and after bariatric surgery

Raúl Jiménez-Agüero, José I Emparanza, Adolfo Beguiristain, Luis Bujanda, José M Alustiza, Elisabeth García, Elizabeth Hijona, Lander Gallego, Javier Sánchez-González, María J Perugorria, José I Asensio, Santiago Larburu, Maddi Garmendia, Mikel Larzabal, María P Portillo, Leixuri Aguirre, Jesús M Banales

Open Access Research article

Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn’s disease

Dimitrios Polymeros, Zacharias P Tsiamoulos, Andreas L Koutsoumpas, Daniel S Smyk, Maria G Mytilinaiou, Konstantinos Triantafyllou, Dimitrios P Bogdanos, Spiros D Ladas

Open Access Research article

Two distinct Do-Not-Resuscitate protocols leaving less to the imagination: an observational study using propensity score matching

Yen-Yuan Chen, Nahida H Gordon, Alfred F Connors, Allan Garland, Shan-Chwen Chang, Stuart J Youngner

Open Access Review

Predicting outcome from dengue

Sophie Yacoub, Bridget Wills

Open Access Research article

Immunological markers of Plasmodium vivaxexposure and immunity: a systematic review and meta-analysis

Julia C Cutts, Rosanna Powell, Paul A Agius, James G Beeson, Julie A Simpson, Freya J I Fowkes

Open Access Research article

Non-invasive score identifies ultrasonography-diagnosed non-alcoholic fatty liver disease and predicts mortality in the USA

Ching-Lung Cheung, Karen SL Lam, Ian CK Wong, Bernard MY Cheung

Open Access Review

Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions

Wendy Stevens, Natasha Gous, Nathan Ford, Lesley E Scott

Open Access Opinion

Towards identification of true cancer biomarkers

Eleftherios P Diamandis

Open Access Commentary

Molecular mimicry, inflammatory bowel disease, and the vaccine safety debate

Susy Yusung, Jonathan Braun

Open Access Research article

Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis

Ling-Wei Chen, Yi Wu, Nithya Neelakantan, Mary Foong-Fong Chong, An Pan, Rob M van Dam

Open Access Research article

Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis

Ali A Mokdad, Alan D Lopez, Saied Shahraz, Rafael Lozano, Ali H Mokdad, Jeff Stanaway, Christopher JL Murray, Mohsen Naghavi

Open Access Commentary

Preventing pre-eclampsia - are dietary factors the key?

Jodie M Dodd, Cecelia O’Brien, Rosalie M Grivell

Open Access Research article

Dietary calcium intake and mortality risk from cardiovascular disease and all causes: a meta-analysis of prospective cohort studies

Xia Wang, Hongxia Chen, Yingying Ouyang, Jun Liu, Gang Zhao, Wei Bao, Maosheng Yan

Open Access Research article

Visit-to-visit variability of fasting plasma glucose as predictor of ischemic stroke: competing risk analysis in a national cohort of Taiwan Diabetes Study

Cheng-Chieh Lin, Chun-Pai Yang, Chia-Ing Li, Chiu-Shong Liu, Ching-Chu Chen, Wen-Yuan Lin, Kai-Lin Hwang, Sing-Yu Yang, Tsai-Chung Li

Open Access Research article

Risk of violence from the man involved in the pregnancy after receiving or being denied an abortion

Sarah CM Roberts, M Antonia Biggs, Karuna S Chibber, Heather Gould, Corinne H Rocca, Diana Greene Foster

Open Access Research article

Concordance between DSM-IV and DSM-5 criteria for delirium diagnosis in a pooled database of 768 prospectively evaluated patients using the delirium rating scale-revised-98

David J Meagher, Alessandro Morandi, Sharon K Inouye, Wes Ely, Dimitrios Adamis, Alasdair J Maclullich, James L Rudolph, Karin Neufeld, Maeve Leonard, Giuseppe Bellelli, Daniel Davis, Andrew Teodorczuk, Stefan Kreisel, Christine Thomas, Wolfgang Hasemann, Suzanne Timmons, Niamh O’Regan, Sandeep Grover, Faiza Jabbar, Walter Cullen, Colum Dunne, Barbara Kamholz, Barbara C Van Munster, Sophia E De Rooij, Jos De Jonghe, Paula T Trzepacz

Open Access Commentary

Peer review for biomedical publications: we can improve the system

Philip F Stahel, Ernest E Moore

Open Access Commentary

The atrial fibrillation epidemic is approaching the physician's door: will mobile technology improve detection?

Perttu J Lindsberg, Lauri Toivonen, Hans-Christoph Diener

Open Access Research article

Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway 2008-2012

Inger Johanne Bakken, Kari Tveito, Nina Gunnes, Sara Ghaderi, Camilla Stoltenberg, Lill Trogstad, Siri Eldevik H åberg, Per Magnus

Open Access Research article

Validity of self-measured waist circumference in adults at risk of type 2 diabetes and cardiovascular disease

Ana María Contardo Ayala, Giel Nijpels, Jeroen Lakerveld

Open Access Research article

Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden

Katie I Gallacher, G David Batty, Gary McLean, Stewart W Mercer, Bruce Guthrie, Carl R May, Peter Langhorne, Frances S Mair

Open Access Commentary

How do you circumcise a nation? The Rwandan case study

Vincent Mutabazi, Jamie I Forrest, Nathan Ford, Edward J Mills

Open Access Research article

The impact of dialysis therapy on older patients with advanced chronic kidney disease: a nationwide population-based study

Chia-Jen Shih, Yung-Tai Chen, Shuo-Ming Ou, Wu-Chang Yang, Shu-Chen Kuo, Der-Cherng Tarng

Open Access Research article

Standard laboratory tests to identify older adults at increased risk of death

Susan E Howlett, Michael RH Rockwood, Arnold Mitnitski, Kenneth Rockwood

Open Access Research article

Association of behaviour change techniques with effectiveness of dietary interventions among adults of retirement age: a systematic review and meta-analysis of randomised controlled trials

Jose Lara, Elizabeth H Evans, Nicola O’Brien, Paula J Moynihan, Thomas D Meyer, Ashley J Adamson, Linda Errington, Falko F Sniehotta, Martin White, John C Mathers

Open Access Research article

Combining varenicline and nicotine patches: a randomized controlled trial study in smoking cessation

Josep M Ramon, Sergio Morchon, Antoni Baena, Cristina Masuet-Aumatell

Open Access Research article

Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study

Krasimira Aleksandrova, Tobias Pischon, Mazda Jenab, H Bas Bueno-de-Mesquita, Veronika Fedirko, Teresa Norat, Dora Romaguera, Sven Knüppel, Marie-Christine Boutron-Ruault, Laure Dossus, Laureen Dartois, Rudolf Kaaks, Kuanrong Li, Anne Tjønneland, Kim Overvad, José Ramón Quirós, Genevieve Buckland, María José Sánchez, Miren Dorronsoro, Maria-Dolores Chirlaque, Aurelio Barricarte, Kay-Tee Khaw, Nicholas J Wareham, Kathryn E Bradbury, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli, Vittorio Krogh, Rosario Tumino, Alessio Naccarati, Salvatore Panico, Peter D Siersema, Petra HM Peeters, Ingrid Ljuslinder, Ingegerd Johansson, Ulrika Ericson, Bodil Ohlsson, Elisabete Weiderpass, Guri Skeie, Kristin Benjaminsen Borch, Sabina Rinaldi, Isabelle Romieu, Joyce Kong, Marc J Gunter, Heather A Ward, Elio Riboli, Heiner Boeing

Open Access Research article

Visual impairment is associated with physical and mental comorbidities in older adults: a cross-sectional study

Helen Court, Gary McLean, Bruce Guthrie, Stewart W Mercer, Daniel J Smith

Open Access Review

Transmission dynamics and control of Ebola virus disease (EVD): a review

Gerardo Chowell, Hiroshi Nishiura

Open Access Guideline

Pain care for patients with epidermolysis bullosa: best care practice guidelines

Kenneth R Goldschneider, Julie Good, Emily Harrop, Christina Liossi, Anne Lynch-Jordan, Anna E Martinez, Lynne G Maxwell, Danette Stanko-Lopp

Open Access Research article

The effects of antenatal dietary and lifestyle advice for women who are overweight or obese on maternal diet and physical activity: the LIMIT randomised trial

Jodie M Dodd, Courtney Cramp, Zhixian Sui, Lisa N Yelland, Andrea R Deussen, Rosalie M Grivell, Lisa J Moran, Caroline A Crowther, Deborah Turnbull, Andrew J McPhee, Gary Wittert, Julie A Owens, Jeffrey S Robinson

Open Access Research article

The effects of antenatal dietary and lifestyle advice for women who are overweight or obese on neonatal health outcomes: the LIMIT randomised trial

Jodie M Dodd, Andrew J McPhee, Deborah Turnbull, Lisa N Yelland, Andrea R Deussen, Rosalie M Grivell, Caroline A Crowther, Gary Wittert, Julie A Owens, Jeffrey S Robinson

Open Access Commentary

Obesity in pregnancy: could lifestyle interventions work?

Lucilla Poston

Open Access Commentary

Environmental enteropathy and malnutrition: do we know enough to intervene?

William A Petri, Caitlin Naylor, Rashidul Haque

Open Access Research article

Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study

Lindsey M Warkentin, Sumit R Majumdar, Jeffrey A Johnson, Calypse B Agborsangaya, Christian F Rueda-Clausen, Arya M Sharma, Scott W Klarenbach, Shahzeer Karmali, Daniel W Birch, Raj S Padwal

Open Access Research article

Limited antigenic diversity of Plasmodium falciparumapical membrane antigen 1 supports the development of effective multi-allele vaccines

Ulrich Terheggen, Damien R Drew, Anthony N Hodder, Nadia J Cross, Cleopatra K Mugyenyi, Alyssa E Barry, Robin F Anders, Sheetij Dutta, Faith HA Osier, Salenna R Elliott, Nicolas Senn, Danielle I Stanisic, Kevin Marsh, Peter M Siba, Ivo Mueller, Jack S Richards, James G Beeson

Open Access Commentary

Candidate gene-environment interactions in breast cancer

Olivia Fletcher, Frank Dudbridge

Open Access Research article

Is chronic inhibition of phosphodiesterase type 5 cardioprotective and safe? A meta-analysis of randomized controlled trials

Elisa Giannetta, Tiziana Feola, Daniele Gianfrilli, Riccardo Pofi, Valentina Dall’Armi, Roberto Badagliacca, Federica Barbagallo, Andrea Lenzi, Andrea M Isidori

Open Access Opinion

Why does society accept a higher risk for alcohol than for other voluntary or involuntary risks?

Jürgen Rehm, Dirk W Lachenmeier, Robin Room

Open Access Research article

Quantitative analysis of computed tomography images and early detection of cerebral edema for pediatric traumatic brain injury patients: retrospective study

Hakseung Kim, Gwang-dong Kim, Byung C Yoon, Keewon Kim, Byung-Jo Kim, Young Hun Choi, Marek Czosnyka, Byung-Mo Oh, Dong-Joo Kim

Open Access Forum

Remembering the forgotten non-communicable diseases

Alan D Lopez, Thomas N Williams, Adeera Levin, Marcello Tonelli, Jasvinder A Singh, Peter GJ Burney, Jürgen Rehm, Nora D Volkow, George Koob, Cleusa P Ferri

Open Access Research article

Epidemiology of multimorbidity in China and implications for the healthcare system: cross-sectional survey among 162,464 community household residents in southern China

Harry HX Wang, Jia Ji Wang, Samuel YS Wong, Martin CS Wong, Fang Jian Li, Pei Xi Wang, Zhi Heng Zhou, Chun Yan Zhu, Sian M Griffiths, Stewart W Mercer

Open Access Research article

Trends in and disparities for acute myocardial infarction: an analysis of Medicare claims data from 1992 to 2010

Jasvinder A Singh, Xin Lu, Said Ibrahim, Peter Cram

Open Access Correspondence

Five-step authorship framework to improve transparency in disclosing contributors to industry-sponsored clinical trial publications

Ana Maruš.ić, Darko Hren, Bernadette Mansi, Neil Lineberry, Ananya Bhattacharya, Maureen Garrity, Juli Clark, Thomas Gesell, Susan Glasser, John Gonzalez, Carolyn Hustad, Mary-Margaret Lannon, LaVerne A Mooney, Teresa Peña

Open Access Research article

Antibodies against H10N8 avian influenza virus among animal workers in Guangdong Province before November 30, 2013, when the first human H10N8 case was recognized

Wenbao Qi, Shuo Su, Chencheng Xiao, Pei Zhou, Huanan Li, Changwen Ke, Gregory C Gray, Guihong Zhang, Ming Liao

Open Access Commentary

Challenges of synthesizing medical education research

Rachel H Ellaway

Open Access Research article

Comorbidity and dementia: a scoping review of the literature

Frances Bunn, Anne-Marie Burn, Claire Goodman, Greta Rait, Sam Norton, Louise Robinson, Johan Schoeman, Carol Brayne

Open Access Research article

Is a specialist breathlessness service more effective and cost-effective for patients with advanced cancer and their carers than standard care? Findings of a mixed-method randomised controlled trial

Morag C Farquhar, A Toby Prevost, Paul McCrone, Barbara Brafman-Price, Allison Bentley, Irene J Higginson, Chris Todd, Sara Booth

Open Access Research article

FTOrs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients

Daniel Pineda-Tenor, Juan Berenguer, María A Jiménez-Sousa, Mónica García-Alvarez, Teresa Aldámiz-Echevarria, Ana Carrero, Sonia Vázquez-Morón, Pilar García-Broncano, Cristina Diez, Francisco Tejerina, María Guzmán-Fulgencio, Salvador Resino

Open Access Research article

The effects of HIV testing advocacy messages on test acceptance: a randomized clinical trial

Monica L Kasting, Anthony D Cox, Dena Cox, Kenneth H Fife, Barry P Katz, Gregory D Zimet

Open Access Review

Cardiovascular risk factors and future risk of Alzheimer’s disease

Renée FAG de Bruijn, M Arfan Ikram

Open Access Research article

Treatment of vascular risk factors in patients with a diagnosis of Alzheimer’s disease: a systematic review

Raffaella Valenti, Leonardo Pantoni, Hugh S Markus

Open Access Editorial

Vascular risk factors and Alzheimer’s disease

John T O’Brien, Hugh S Markus

Open Access Erratum

Erratum to: preventing the development of depression at work: a systematic review and meta-analysis of universal interventions in the workplace

Leona Tan, Min-Jung Wang, Matthew Modini, Sadhbh Joyce, Arnstein Mykletun, Helen Christensen, Samuel B Harvey

Open Access Opinion

Preventing mental health problems in offspring by targeting dietary intake of pregnant women

Adrienne O'Neil, Catherine Itsiopoulos, Helen Skouteris, Rachelle S Opie, Skye McPhie, Briony Hill, Felice N Jacka

Open Access Research article

Mortality attributable to Plasmodium vivaxmalaria: a clinical audit from Papua, Indonesia

Nicholas M Douglas, Gysje J Pontororing, Daniel A Lampah, Tsin W Yeo, Enny Kenangalem, Jeanne Rini Poespoprodjo, Anna P Ralph, Michael J Bangs, Paulus Sugiarto, Nicholas M Anstey, Ric N Price

Open Access Research article

A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment

Takayuki Nakagawa, Kozo Kumakawa, Shin-ichi Usami, Naohito Hato, Keiji Tabuchi, Mariko Takahashi, Keizo Fujiwara, Akira Sasaki, Shizuo Komune, Tatsunori Sakamoto, Harukazu Hiraumi, Norio Yamamoto, Shiro Tanaka, Harue Tada, Michio Yamamoto, Atsushi Yonezawa, Toshiko Ito-Ihara, Takafumi Ikeda, Akira Shimizu, Yasuhiko Tabata, Juichi Ito

Open Access Research article

Dairy consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis

Mu Chen, Qi Sun, Edward Giovannucci, Dariush Mozaffarian, JoAnn E Manson, Walter C Willett, Frank B Hu

Open Access Research article

Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis

Stephen E Borst, Jonathan J Shuster, Baiming Zou, Fan Ye, Huanguang Jia, Anita Wokhlu, Joshua F Yarrow

Open Access Research article

Elevated risk of stillbirth in males: systematic review and meta-analysis of more than 30 million births

Debapriya Mondal, Tamara S Galloway, Trevor C Bailey, Fiona Mathews

Open Access Research article

Mental, neurological, and substance use problems among refugees in primary health care: analysis of the Health Information System in 90 refugee camps

Jeremy C Kane, Peter Ventevogel, Paul Spiegel, Judith K Bass, Mark van Ommeren, Wietse A Tol

Open Access Research article

Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women

Martin N Mwangi, Sumi Maskey, Pauline EA Andang’o, Noel K Shinali, Johanna M Roth, Laura Trijsburg, Alice M Mwangi, Han Zuilhof, Barend van Lagen, Huub FJ Savelkoul, Ayşe Y Demir, Hans Verhoef

Open Access Research article

Risk of low bone mineral density and low body mass index in patients with non-celiac wheat-sensitivity: a prospective observation study

Antonio Carroccio, Maurizio Soresi, Alberto D’Alcamo, Carmelo Sciumè, Giuseppe Iacono, Girolamo Geraci, Ignazio Brusca, Aurelio Seidita, Floriana Adragna, Miriam Carta, Pasquale Mansueto

Open Access Correspondence

Clinical considerations and key issues in the management of patients with Erdheim-Chester Disease: a seven case series

Roei D Mazor, Mirra Manevich-Mazor, Anat Kesler, Orna Aizenstein, Iris Eshed, Ronald Jaffe, Yakov Pessach, Ilan Goldberg, Eli Sprecher, Iris Yaish, Alexander Gural, Chezi Ganzel, Yehuda Shoenfeld

Open Access Research article

miRNAs can be generally associated with human pathologies as exemplified for miR-144*

Andreas Keller, Petra Leidinger, Britta Vogel, Christina Backes, Abdou ElSharawy, Valentina Galata, Sabine C Mueller, Sabine Marquart, Michael G Schrauder, Reiner Strick, Andrea Bauer, Jörg Wischhusen, Markus Beier, Jochen Kohlhaas, Hugo A Katus, Jörg Hoheisel, Andre Franke, Benjamin Meder, Eckart Meese

Open Access Correspondence

The Ariadne principles: how to handle multimorbidity in primary care consultations

Christiane Muth, Marjan van den Akker, Jeanet W Blom, Christian D Mallen, Justine Rochon, François G Schellevis, Annette Becker, Martin Beyer, Jochen Gensichen, Hanna Kirchner, Rafael Perera, Alexandra Prados-Torres, Martin Scherer, Ulrich Thiem, Hendrik van den Bussche, Paul P Glasziou

Open Access Research article

DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma

Brittany N Lasseigne, Todd C Burwell, Mohini A Patil, Devin M Absher, James D Brooks, Richard M Myers

Open Access Research article

The burden of disease in Spain: results from the global burden of disease study 2010

Josep Maria Haro, Stefanos Tyrovolas, Noe Garin, Cesar Diaz-Torne, Loreto Carmona, Lidia Sanchez-Riera, Fernando Perez-Ruiz, Christopher JL Murray

Open Access Research article

Diagnosis and treatment of hyponatremia: a systematic review of clinical practice guidelines and consensus statements

Evi V Nagler, Jill Vanmassenhove, Sabine N van der Veer, Ionut Nistor, Wim Van Biesen, Angela C Webster, Raymond Vanholder

Open Access Research article

Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of pregnancy: a cross-sectional study

Ping-Ping Lv, Ye Meng, Min Lv, Chun Feng, Ye Liu, Jing-Yi Li, Dan-Qin Yu, Yan Shen, Xiao-Lin Hu, Qian Gao, Shan Dong, Xian-Hua Lin, Gu-Feng Xu, Shen Tian, Dan Zhang, Fang-Hong Zhang, Jie-Xue Pan, Xiao-Qun Ye, Miao-E Liu, Xin-Mei Liu, Jian-Zhong Sheng, Guo-Lian Ding, He-Feng Huang

Open Access Research article

Sex dependent risk factors for mortality after myocardial infarction: individual patient data meta-analysis

Hanna M van Loo, Edwin R van den Heuvel, Robert A Schoevers, Matteo Anselmino, Robert M Carney, Johan Denollet, Frank Doyle, Kenneth E Freedland, Sherry L Grace, Seyed H Hosseini, Kapil Parakh, Louise Pilote, Chiara Rafanelli, Annelieke M Roest, Hiroshi Sato, Richard P Steeds, Ronald C Kessler, Peter de Jonge

Open Access Research article

Prevalence, distribution, and social determinants of tobacco use in 30 sub-Saharan African countries

Chandrashekhar T Sreeramareddy, Pranil Mansingh Pradhan, Shwe Sin

Open Access Research article

National household survey of adverse childhood experiences and their relationship with resilience to health-harming behaviors in England

Mark A Bellis, Karen Hughes, Nicola Leckenby, Clare Perkins, Helen Lowey

Open Access Review

Update on the NCEP ATP-III emerging cardiometabolic risk factors

Robert H Eckel, Marc-Andre Cornier

Open Access Editorial

Obscurity on Obesity

Jack Winkler

Open Access Research article

Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets

Elin Hall, Petr Volkov, Tasnim Dayeh, Karl Bacos, Tina Rönn, Marloes Dekker Nitert, Charlotte Ling

Open Access Research article

Outcomes of polytrauma patients with diabetes mellitus

James Tebby, Fiona Lecky, Antoinette Edwards, Tom Jenks, Omar Bouamra, Rozalia Dimitriou, Peter V Giannoudis

Open Access Research article

Estimating the returns to UK publicly funded cancer-related research in terms of the net value of improved health outcomes

Matthew Glover, Martin Buxton, Susan Guthrie, Stephen Hanney, Alexandra Pollitt, Jonathan Grant

Open Access Research article

Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis

Jing Huang, Gang Liu, Yi-miao Zhang, Zhao Cui, Fang Wang, Xiao-jing Liu, Rong Chu, Ming-hui Zhao

Open Access Research article

Accuracy of epidemiological inferences based on publicly available information: retrospective comparative analysis of line lists of human cases infected with influenza A(H7N9) in China

Eric HY Lau, Jiandong Zheng, Tim K Tsang, Qiaohong Liao, Bryan Lewis, John S Brownstein, Sharon Sanders, Jessica Y Wong, Sumiko R Mekaru, Caitlin Rivers, Peng Wu, Hui Jiang, Yu Li, Jianxing Yu, Qian Zhang, Zhaorui Chang, Fengfeng Liu, Zhibin Peng, Gabriel M Leung, Luzhao Feng, Benjamin J Cowling, Hongjie Yu

Open Access Research article

Predictive spatial risk model of poliovirus to aid prioritization and hasten eradication in Nigeria

Alexander M Upfill-Brown, Hil M Lyons, Muhammad A Pate, Faisal Shuaib, Shahzad Baig, Hao Hu, Philip A Eckhoff, Guillaume Chabot-Couture

Open Access Research article

Inequalities in child mortality in ten major African cities

Wilm Quentin, Olayinka Abosede, Joseph Aka, Patricia Akweongo, Kouassi Dinard, Alex Ezeh, Ramadan Hamed, Patrick Kalambayi Kayembe, Getnet Mitike, Gemini Mtei, Marguerite Te Bonle, Leonie Sundmacher

Open Access Research article

Outpatient antibiotic prescribing in the United States: 2000 to 2010

Grace C Lee, Kelly R Reveles, Russell T Attridge, Kenneth A Lawson, Ishak A Mansi, James S Lewis II, Christopher R Frei

Open Access Commentary

β cells keep bad epigenetic memories of palmitate

Delphine Fradin, Pierre Bougnères

Open Access Comment

Does reductio ad absurdumhave a place in evidence-based medicine?

Florian Naudet, Bruno Falissard

Open Access Research article

Can authorities appreciably enhance the prescribing of oral generic risperidone to conserve resources? Findings from across Europe and their implications

Brian Godman, Max Petzold, Kathleen Bennett, Marion Bennie, Anna Bucsics, Alexander E Finlayson, Andrew Martin, Marie Persson, Jutta Piessnegger, Emanuel Raschi, Steven Simoens, Corinne Zara, Corrado Barbui

Open Access Research article

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous pericarditis compared to adenosine deaminase and unstimulated interferon-γ in a high burden setting: a prospective study

Shaheen Pandie, Jonathan G Peter, Zita S Kerbelker, Richard Meldau, Grant Theron, Ureshnie Govender, Mpiko Ntsekhe, Keertan Dheda, Bongani M Mayosi

Open Access Research article

A process for assessing the feasibility of a network meta-analysis: a case study of everolimus in combination with hormonal therapy versus chemotherapy for advanced breast cancer

Shannon Cope, Jie Zhang, Stephen Saletan, Brielan Smiechowski, Jeroen P Jansen, Peter Schmid

Open Access Research article

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother–child cohort study

Léa Maitre, Eleni Fthenou, Toby Athersuch, Muireann Coen, Mireille B Toledano, Elaine Holmes, Manolis Kogevinas, Leda Chatzi, Hector C Keun

Open Access Research article

Impact of early daycare on healthcare resource use related to upper respiratory tract infections during childhood: prospective WHISTLER cohort study

Marieke LA de Hoog, Roderick P Venekamp, Cornelis K van der Ent, Anne Schilder, Elisabeth AM Sanders, Roger AMJ Damoiseaux, Debby Bogaert, Cuno SPM Uiterwaal, Henriette A Smit, Patricia Bruijning-Verhagen

Open Access Research article

Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria

Faith HA Osier, Gaoqian Feng, Michelle J Boyle, Christine Langer, Jingling Zhou, Jack S Richards, Fiona J McCallum, Linda Reiling, Anthony Jaworowski, Robin F Anders, Kevin Marsh, James G Beeson

Open Access Research article

Adaptation and validation of the Treatment Burden Questionnaire (TBQ) in English using an internet platform

Viet-Thi Tran, Magdalena Harrington, Victor M Montori, Caroline Barnes, Paul Wicks, Philippe Ravaud

Open Access Forum

Definitions and potential health benefits of the Mediterranean diet: views from experts around the world

Antonia Trichopoulou, Miguel A Martínez-González, Tammy YN Tong, Nita G Forouhi, Shweta Khandelwal, Dorairaj Prabhakaran, Dariush Mozaffarian, Michel de Lorgeril

Open Access Research article

A cohort study on the incidence and outcome of pulmonary embolism in trauma and orthopedic patients

Suribabu Gudipati, Evangelos M Fragkakis, Vincenzo Ciriello, Simon J Harrison, Petros Z Stavrou, Nikolaos K Kanakaris, Robert M West, Peter V Giannoudis

Open Access Research article

Classification of healthcare-associated infection: a systematic review 10 years after the first proposal

Teresa Cardoso, Mónica Almeida, N Deborah Friedman, Irene Aragão, Altamiro Costa-Pereira, António E Sarmento, Luís Azevedo

Open Access Research article

Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis

Georg M Fröhlich, Alexandra J Lansky, John Webb, Marco Roffi, Stefan Toggweiler, Markus Reinthaler, Duolao Wang, Nevil Hutchinson, Olaf Wendler, David Hildick-Smith, Pascal Meier

Open Access Correspondence

Strengths and weaknesses of guideline approaches to safeguard voluntary informed consent of patients within a dependent relationship

Sara AS Dekking, Rieke van der Graaf, Johannes JM van Delden

Open Access Opinion

The Lives Saved Tool (LiST) as a model for diarrhea mortality reduction

Christa L Fischer Walker, Neff Walker

Open Access Opinion

Do statins increase and Mediterranean diet decrease the risk of breast cancer?

Michel de Lorgeril, Patricia Salen

Open Access Question and Answer

Video Q & A: The impact of stress. An interview with George Chrousos

George Chrousos

Open Access Review

Managing the changing burden of cancer in Asia

Rengaswamy Sankaranarayanan, Kunnambath Ramadas, You-lin Qiao

Open Access Research article

Marital status and ischemic heart disease incidence and mortality in women: a large prospective study

Sarah Floud, Angela Balkwill, Dexter Canoy, F Lucy Wright, Gillian K Reeves, Jane Green, Valerie Beral, Benjamin J Cairns

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