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Zeitschrift

BMC Pulmonary Medicine

BMC Pulmonary Medicine 1/2017

Ausgabe 1/2017

Inhaltsverzeichnis ( 219 Artikel )

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

BreathDx – molecular analysis of exhaled breath as a diagnostic test for ventilator–associated pneumonia: protocol for a European multicentre observational study

Pouline M. P. van Oort, Tamara Nijsen, Hans Weda, Hugo Knobel, Paul Dark, Timothy Felton, Nicholas J. W. Rattray, Oluwasola Lawal, Waqar Ahmed, Craig Portsmouth, Peter J. Sterk, Marcus J. Schultz, Tetyana Zakharkina, Antonio Artigas, Pedro Povoa, Ignacio Martin-Loeches, Stephen J. Fowler, Lieuwe D. J. Bos, on behalf of the BreathDx Consortium

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Knowledge, attitudes and practices regarding tuberculosis care among health workers in Southern Mozambique

Andrés Noé, Rafaela M. Ribeiro, Rui Anselmo, Maria Maixenchs, Layce Sitole, Khatia Munguambe, Silvia Blanco, Peter le Souef, Alberto L. García-Basteiro

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Household biomass fuel use, asthma symptoms severity, and asthma underdiagnosis in rural schoolchildren in Nigeria: a cross-sectional observational study

Oluwafemi Oluwole, Ganiyu O. Arinola, Dezheng Huo, Christopher O. Olopade

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Childhood asthma, asthma severity indicators, and related conditions along an urban-rural gradient: a cross-sectional study

Joshua A. Lawson, Donna C. Rennie, Don W. Cockcroft, Roland Dyck, Anna Afanasieva, Oluwafemi Oluwole, Jinnat Afsana

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Characteristics associated with progression in patients with of nontuberculous mycobacterial lung disease : a prospective cohort study

Soo Jung Kim, Soon Ho Yoon, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sung Koo Han, Jae-Joon Yim

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prevalence of airflow obstruction in patients with stable systolic heart failure

Morten Dalsgaard, Louis Lind Plesner, Morten Schou, Erik Kjøller, Jørgen Vestbo, Kasper Iversen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

End-tidal capnographic monitoring to detect apnea episodes during flexible bronchoscopy under sedation

Tsukasa Ishiwata, Kenji Tsushima, Mai Fujie, Kenichi Suzuki, Kosuke Hirota, Mitsuhiro Abe, Naoko Kawata, Jiro Terada, Koichiro Tatsumi

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Multi-center, randomized, placebo-controlled trial of nocturnal oxygen therapy in chronic obstructive pulmonary disease: a study protocol for the INOX trial

Yves Lacasse, Sarah Bernard, Frédéric Sériès, Van Hung Nguyen, Jean Bourbeau, Shawn Aaron, François Maltais, for the International Nocturnal Oxygen (INOX) Research Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effects of ventilator settings, nebulizer and exhalation port position on albuterol delivery during non-invasive ventilation: an in-vitro study

Yuda Sutherasan, Lorenzo Ball, Pasquale Raimondo, Valentina Caratto, Elisa Sanguineti, Federico Costantino, Maurizio Ferretti, Robert M. Kacmarek, Paolo Pelosi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Implementing flexible bronchoscopy in least developed countries according to international guidelines is feasible and sustainable: example from Phnom-Penh, Cambodia

Martin Veaudor, Sébastien Couraud, Sophors Chan, Chanraksmey Choun, Pisethmorokoth Keo, Virginie Avrillon, Pierre-Jean Souquet, Chanty Ny

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

B-type natriuretic peptides in chronic obstructive pulmonary disease: a systematic review

Nathaniel M. Hawkins, Amit Khosla, Sean A. Virani, John J. V. McMurray, J Mark FitzGerald

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Recurrent pneumonia among Japanese adults: disease burden and risk factors

Tomoko Ishifuji, Eiichiro Sando, Norihiro Kaneko, Motoi Suzuki, Paul E. Kilgore, Koya Ariyoshi, Konosuke Morimoto, Naoto Hosokawa, Makito Yaegashi, Masahiro Aoshima, on behalf of the Adult Pneumonia Study Group - Japan (APSG-J)

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

What patients really think about asthma guidelines: barriers to guideline implementation from the patients’ perspective

H. Lingner, B. Burger, P. Kardos, C. P. Criée, H. Worth, E. Hummers-Pradier

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effects of treadmill exercise versus Flutter® on respiratory flow and sputum properties in adults with cystic fibrosis: a randomised, controlled, cross-over trial

Tiffany J. Dwyer, Rahizan Zainuldin, Evangelia Daviskas, Peter T. P. Bye, Jennifer A. Alison

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis

Milica Vukmirovic, Jose D. Herazo-Maya, John Blackmon, Vesna Skodric-Trifunovic, Dragana Jovanovic, Sonja Pavlovic, Jelena Stojsic, Vesna Zeljkovic, Xiting Yan, Robert Homer, Branko Stefanovic, Naftali Kaminski

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Are risk predicting models useful for estimating survival of patients with rheumatoid arthritis-associated interstitial lung disease?

Hanna M. Nurmi, Minna K. Purokivi, Miia S. Kärkkäinen, Hannu-Pekka Kettunen, Tuomas A. Selander, Riitta L. Kaarteenaho

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Successful outcome following pneumonectomy in a teenage boy with cystic fibrosis: a case report

Zheyi Liew, Santosh Mallikarjuna, Asif Hasan, F. Kate Gould, Su Bunn, Matthew F. Thomas, Jim L. Lordan, Christopher O’Brien, Malcolm Brodlie

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A follow-up study of airway symptoms and lung function among residents and workers 5.5 years after an oil tank explosion

Jens-Tore Granslo, Magne Bråtveit, Bjørg Eli Hollund, Stein Håkon Låstad Lygre, Cecilie Svanes, Bente Elisabeth Moen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A novel reflex cough testing device

Kazunori Fujiwara, Katsuyuki Kawamoto, Yoko Shimizu, Takahiro Fukuhara, Satoshi Koyama, Hideyuki Kataoka, Hiroya Kitano, Hiromi Takeuchi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Can healthcare utilization data reliably capture cases of chronic respiratory diseases? a cross-sectional investigation in Italy

A Biffi, R Comoretto, A Arfè, L Scotti, L Merlino, A Vaghi, A Pesci, R de Marco, G Corrao, on behalf of the “CRD Real-World Evidence” scientific board

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cystic fibrosis physicians’ perspectives on the timing of referral for lung transplant evaluation: a survey of physicians in the United States

Kathleen J. Ramos, Ranjani Somayaji, Erika D. Lease, Christopher H. Goss, Moira L. Aitken

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

A prospective pilot study of home monitoring in adults with cystic fibrosis (HOME-CF): protocol for a randomised controlled trial

Jocelyn Choyce, Karen L. Shaw, Alice J. Sitch, Hema Mistry, Joanna L. Whitehouse, Edward F. Nash

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Effects of periodontal treatment on exacerbation frequency and lung function in patients with chronic periodontitis: study protocol of a 1-year randomized controlled trial

Sergio Romero Santos, Erika Horácio Pinto, Priscila Larcher Longo, Simone Dal Corso, Fernanda Cordoba Lanza, Rafael Stelmach, Samia Zahi Rached, Adriana Lino-dos-Santos-Franco, Marcia Pinto Alves Mayer, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Anna Carolina Ratto Tempestini Horliana

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Epigenetic modifying enzyme expression in asthmatic airway epithelial cells and fibroblasts

Dorota Stefanowicz, Jari Ullah, Kevin Lee, Furquan Shaheen, Ekiomoado Olumese, Nick Fishbane, Hyun-Kyoung Koo, Teal S. Hallstrand, Darryl A. Knight, Tillie-Louise Hackett

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Immediate salbutamol responsiveness does not predict long-term benefits of indacaterol in patients with chronic obstructive pulmonary disease

Pierre-Régis Burgel, Vincent Le Gros, Laurent Decuypère, Isabelle Bourdeix, Thierry Perez, Gaëtan Deslée

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pulmonary oxygen uptake and muscle deoxygenation kinetics during heavy intensity cycling exercise in patients with emphysema and idiopathic pulmonary fibrosis

Melitta A. McNarry, Nicholas K. Harrison, Tom Withers, Narendra Chinnappa, Michael J. Lewis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Airway wall thickness on HRCT scans decreases with age and increases with smoking

Eef D. Telenga, Matthijs Oudkerk, Peter M. A. van Ooijen, Rozemarijn Vliegenthart, Nick H. T. ten Hacken, Dirkje S. Postma, Maarten van den Berge

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Development of a respiratory severity score for hospitalized adults in a high HIV-prevalence setting—South Africa, 2010–2011

Alexander J. Millman, Adena Greenbaum, Sibongile Walaza, Adam L. Cohen, Michelle J. Groome, Carrie Reed, Meredith McMorrow, Stefano Tempia, Marietjie Venter, Florette K. Treurnicht, Shabir A. Madhi, Cheryl Cohen, Ebrahim Variava

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries

Derek W. Russell, David R. Janz, William L. Emerson, Addison K. May, Gordon R. Bernard, Zhiguo Zhao, Tatsuki Koyama, Lorraine B. Ware

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Hemosiderin-laden macrophages are an independent factor correlated with pulmonary vascular resistance in idiopathic pulmonary fibrosis: a case control study

Jun Fukihara, Hiroyuki Taniguchi, Masahiko Ando, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Taiki Furukawa, Takeshi Johkoh, Junya Fukuoka, Koji Sakamoto, Yoshinori Hasegawa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of inhaled corticosteroid particle size on asthma efficacy and safety outcomes: a systematic literature review and meta-analysis

Céline El Baou, Rachael L. Di Santostefano, Rafael Alfonso-Cristancho, Elizabeth A Suarez, David Stempel, Mark L Everard, Neil Barnes

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Combined cumulative sum (CUSUM) and chronological environmental analysis as a tool to improve the learning environment for linear-probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) trainees: a pilot study

Yasuhiro Norisue, Yasuharu Tokuda, Mayrol Juarez, Ryo Uchimido, Shigeki Fujitani, David A. Stoeckel

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

First time identification of Pandoraea sputorum from a patient with cystic fibrosis in Argentina: a case report

Pablo F. Martina, Mónica Martínez, Guillermo Frada, Florencia Alvarez, Lorena Leguizamón, Claudia Prieto, Carolina Barrias, Marisa Bettiol, Antonio Lagares, Alejandra Bosch, Julián Ferreras, Martha Von Specht

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome

Anup Das, Mainul Haque, Marc Chikhani, Oana Cole, Wenfei Wang, Jonathan G. Hardman, Declan G. Bates

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation

Brynja Jónsdóttir, Åsa Jaworowski, Carmen San Miguel, Olle Melander

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Early detection of COPD patients in GOLD 0 population: an observational non-interventional cohort study - MARKO study

Žarko Vrbica, Marina Labor, Ivan Gudelj, Slavica Labor, Iva Jurić, Davor Plavec, for the MARKO study group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Observation management of pulmonary embolism and agreement with claims-based and clinical risk stratification criteria in United States patients: a retrospective analysis

Elaine Nguyen, Craig I. Coleman, W. Frank Peacock, Philip S. Wells, Erin R. Weeda, Veronica Ashton, Concetta Crivera, Peter Wildgoose, Jeff R. Schein, Thomas J. Bunz, Gregory J. Fermann

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Extracorporeal membrane oxygenation for avian influenza A (H7N9) patient with acute respiratory distress syndrome: a case report and short literature review

Qi Nie, Ding-yu Zhang, Wen-juan Wu, Chao-lin Huang, Zheng-yi Ni

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Upregulation of interleukin-33 and thymic stromal lymphopoietin levels in the lungs of idiopathic pulmonary fibrosis

Jong-Uk Lee, Hun Soo Chang, Hyeon Ju Lee, Chang An Jung, Da Jeong Bae, Hyun Ji Song, Jong Sook Park, Soo-Taek Uh, Young Hoon Kim, Ki-Hyun Seo, Choon-Sik Park

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile

Masayuki Ito, Kazuyuki Nakagome, Hiromitsu Ohta, Keiichi Akasaka, Yoshitaka Uchida, Atsushi Hashimoto, Ayako Shiono, Toshinori Takada, Makoto Nagata, Jun Tohyama, Koichi Hagiwara, Minoru Kanazawa, Koh Nakata, Ryushi Tazawa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cooking smoke and respiratory symptoms of restaurant workers in Thailand

Chudchawal Juntarawijit, Yuwayong Juntarawijit

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients

Philip J. Lawrence, Umme Kolsum, Vandana Gupta, Gavin Donaldson, Richa Singh, Bethan Barker, Leena George, Adam Webb, Anthony J. Brookes, Christopher Brightling, Jadwiga Wedzicha, Dave Singh

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Birt–Hogg–Dubé syndrome: a literature review and case study of a Chinese woman presenting a novel FLCN mutation

Shengyu Hao, Fei Long, Fenglan Sun, Teng Liu, Daowei Li, Shujuan Jiang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Efficacy of 1, 5, and 20 mg oral sildenafil in the treatment of adults with pulmonary arterial hypertension: a randomized, double-blind study with open-label extension

Carmine Dario Vizza, B. K. S. Sastry, Zeenat Safdar, Lutz Harnisch, Xiang Gao, Min Zhang, Manisha Lamba, Zhi-Cheng Jing

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Persistent asthma phenotype related with late-onset, high atopy, and low socioeconomic status in school-aged Korean children

Eun Lee, Si Hyeon Lee, Ji-Won Kwon, Young-Ho Kim, Jisun Yoon, Hyun-Ju Cho, Song-I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Hyo Bin Kim, So Yeon Lee, Ho-Jang Kwon, Soo-Jong Hong

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer

José Sanz-Santos, Pere Serra, Felipe Andreo, Mohamed Torky, Carmen Centeno, Teresa Morán, Enric Carcereny, Esther Fernández, Samuel García-Reina, Juan Ruiz-Manzano

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Predictors of correct technique in patients using pressurized metered dose inhalers

Kyra Bartolo, Martin Balzan, Emma Louise Schembri, Rachelle Asciak, Darlene Mercieca Balbi, Michael Pace Bardon, Stephen Montefort

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reference equations for spirometric indices from a sample of the general adult population in Nigeria

Ademola Emmanuel Fawibe, Louis O. Odeigah, Mohammed J. Saka

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Effectiveness of pulmonary rehabilitation for patients with asthma: study protocol of a randomized controlled trial (EPRA)

Konrad Schultz, Hildegard Seidl, Danijel Jelusic, Rupert Wagner, Michael Wittmann, Hermann Faller, Dennis Nowak, Michael Schuler

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Switch of noninvasive ventilation (NIV) to continuous positive airway pressure (CPAP) in patients with obesity hypoventilation syndrome: a pilot study

Sarah Orfanos, Dany Jaffuel, Christophe Perrin, Nicolas Molinari, Pascal Chanez, Alain Palot

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Effects of periodontal treatment on exacerbation frequency and lung function in patients with chronic periodontitis: study protocol of a 1-year randomized controlled trial

Sergio dos Santos Romero, Erika Horácio Pinto, Priscila Larcher Longo, Simone Dal Corso, Fernanda Cordoba Lanza, Rafael Stelmach, Samia Zahi Rached, Adriana Lino-dos-Santos-Franco, Marcia Pinto Alves Mayer, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Anna Carolina Ratto Tempestini Horliana

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Chronic cough conundrum: a case report of a new diagnosis of HIV and pulmonary Kaposi’s sarcoma

Pamela P. Bailey, Marylou M. Dryer, John P. Piper, Sajjad Ahmad

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Breathlessness and presentation to the emergency department: a survey and clinical record review

Ann Hutchinson, Alistair Pickering, Paul Williams, J. Martin Bland, Miriam J. Johnson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin, André F. S. Amaral, Matthias Wielscher, Faisal I. Rezwan, Medea Imboden, Marjo-Riitta Jarvelin, Ian M. Adcock, Nicole Probst-Hensch, John W. Holloway, Deborah L. Jarvis, on behalf of the ALEC study

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients

Tsai-Yu Wang, Yu-Lun Lo, Shu-Min Lin, Chien-Da Huang, Fu-Tasi Chung, Horng-Chyuan Lin, Chun-Hua Wang, Han-Pin Kuo

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A prospective observational study to evaluate the effect of social and personality factors on continuous positive airway pressure (CPAP) compliance in obstructive sleep apnoea syndrome

Atul Gulati, Masood Ali, Mike Davies, Tim Quinnell, Ian Smith

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension

Koichiro Higasa, Aiko Ogawa, Chikashi Terao, Masakazu Shimizu, Shinji Kosugi, Ryo Yamada, Hiroshi Date, Hiromi Matsubara, Fumihiko Matsuda

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Healthcare burden of pulmonary hypertension owing to lung disease and/or hypoxia

Gustavo A. Heresi, David M. Platt, Wenyi Wang, Christine H. Divers, Vijay N. Joish, Simon A. Teal, Justin S. Yu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Electromagnetic navigation bronchoscopy to access lung lesions in 1,000 subjects: first results of the prospective, multicenter NAVIGATE study

Sandeep J. Khandhar, Mark R. Bowling, Javier Flandes, Thomas R. Gildea, Kristin L. Hood, William S. Krimsky, Douglas J. Minnich, Septimiu D. Murgu, Michael Pritchett, Eric M. Toloza, Momen M. Wahidi, Jennifer J. Wolvers, Erik E. Folch, for the NAVIGATE Study Investigators

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Hemosiderin in sputum macrophages may predict infective exacerbations of chronic obstructive pulmonary disease: a retrospective observational study

Sindu Mohan, Terence Ho, Melanie Kjarsgaard, Katherine Radford, A. S. M. Borhan, Lehana Thabane, Parameswaran Nair

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A new clinical algorithm scoring for management of suspected foreign body aspiration in children

Ibrahim A. Janahi, Shabina Khan, Prem Chandra, Noora Al-Marri, Ammar Saadoon, Lolwa Al-Naimi, Maryam Al-Thani, William Greer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Validity and reliability of fluoroscopy for digital radiography: a new way to evaluate diaphragmatic mobility

Bruna Estima Leal, Márcia Aparecida Gonçalves, Liseane Gonçalves Lisboa, Larissa Martins Schmitz Linné, Michelle Gonçalves de Souza Tavares, Wellington Pereira Yamaguti, Elaine Paulin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

Yuan Liu, Fuai Lu, Lirong Kang, Zhihua Wang, Yongfu Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of pulmonary arteriovenous malformations on the mechanical properties of the lungs

Cécile Rotenberg, Marcel Bonay, Mostafa El Hajjam, Sandra Blivet, Alain Beauchet, Pascal Lacombe, Thierry Chinet

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment

Christine R. Jenkins, Göran Eriksson, Eric D. Bateman, Helen K. Reddel, Malcolm R. Sears, Magnus Lindberg, Paul M. O’Byrne

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Penicillin treatment for patients with Community-Acquired Pneumonia in Denmark: a retrospective cohort study

Gertrud Baunbæk Egelund, Andreas Vestergaard Jensen, Stine Bang Andersen, Pelle Trier Petersen, Bjarne Ørskov Lindhardt, Christian von Plessen, Gernot Rohde, Pernille Ravn

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of lymphocyte differential count > 15% in BALF on the mortality of patients with acute exacerbation of chronic fibrosing idiopathic interstitial pneumonia

Reoto Takei, Machiko Arita, Shogo Kumagai, Yuhei Ito, Maki Noyama, Fumiaki Tokioka, Tadashi Ishida

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549)

Esmaeil Mortaz, Shamila D. Alipoor, Masoud Movassaghi, Mohammad Varahram, Jahangir Ghorbani, Gert Folkerts, Johan Garssen, Ian M. Adcock

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Asthma–COPD overlap syndrome (ACOS) in primary care of four Latin America countries: the PUMA study

Maria Montes de Oca, Maria Victorina Lopez Varela, Maria E. Laucho-Contreras, Alejandro Casas, Eduardo Schiavi, Juan Carlos Mora

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Co-colonisation with Aspergillus fumigatus and Pseudomonas aeruginosa is associated with poorer health in cystic fibrosis patients: an Irish registry analysis

Emma Reece, Ricardo Segurado, Abaigeal Jackson, Siobhán McClean, Julie Renwick, Peter Greally

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The utility of electron microscopy in detecting asbestos fibers and particles in BALF in diffuse lung diseases

Takashi Kido, Yasuo Morimoto, Kazuhiro Yatera, Hiroshi Ishimoto, Takaaki Ogoshi, Keishi Oda, Kei Yamasaki, Toshinori Kawanami, Shohei Shimajiri, Hiroshi Mukae

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension

Lars Harbaum, Kaaja M. Baaske, Marcel Simon, Tim Oqueka, Christoph Sinning, Antonia Glatzel, Nicole Lüneburg, Karsten Sydow, Carsten Bokemeyer, Hans Klose

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Latin America validation of FACED score in patients with bronchiectasis: an analysis of six cohorts

Rodrigo Athanazio, Mônica Corso Pereira, Georgina Gramblicka, Fernando Cavalcanti-Lundgren, Mara Fernandes de Figueiredo, Francisco Arancibia, Samia Rached, David de la Rosa, Luis Máiz-Carro, Rosa Girón, Casilda Olveira, Concepción Prados, Miguel Angel Martinez-Garcia

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA

Robert Y. Suruki, Jonas B. Daugherty, Nada Boudiaf, Frank C. Albers

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Asthma control using fluticasone propionate/salmeterol in Asian and non-Asian populations: a post hoc analysis of the GOAL study

Jean Bousquet, Neil Barnes, Michael Gibbs, Nadeem Gul, Susan A Tomkins, Xin Zhou, Young-Joo Cho, Hae-Sim Park, William Busse, Nanshan Zhong

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Invasive pulmonary mucormycosis: rare presentation with pulmonary eosinophilia

Taizou Hirano, Mitsuhiro Yamada, Kei Sato, Koji Murakami, Tokiwa Tamai, Yoshiya Mitsuhashi, Tsutomu Tamada, Hisatoshi Sugiura, Naomi Sato, Ryoko Saito, Junya Tominaga, Akira Watanabe, Masakazu Ichinose

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Predictive factors for moderate or severe exacerbations in asthma patients receiving outpatient care

Francisco Javier Álvarez Gutiérrez, Marta Ferrer Galván, Juan Francisco Medina Gallardo, Marta Barrera Mancera, Beatriz Romero Romero, Auxiliadora Romero Falcón

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prognostic factors in hospitalized community-acquired pneumonia: a retrospective study of a prospective observational cohort

Akihiro Ito, Tadashi Ishida, Hironobu Tokumasu, Yasuyoshi Washio, Akio Yamazaki, Yuhei Ito, Hiromasa Tachibana

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Seasonal influenza vaccination in patients with COPD: a systematic literature review

Rafik Bekkat-Berkani, Tom Wilkinson, Philippe Buchy, Gael Dos Santos, Dimitris Stefanidis, Jeanne-Marie Devaster, Nadia Meyer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Epithelial ciliated beating cells essential for ex vivo ALI culture growth

Delphine Gras, Aurélie Petit, Jérémy Charriot, Lucie Knabe, Khuder Alagha, Anne Sophie Gamez, Céline Garulli, Arnaud Bourdin, Pascal Chanez, Nicolas Molinari, Isabelle Vachier

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis

Joseph Jacob, Brian J. Bartholmai, Ryoko Egashira, Anne Laure Brun, Srinivasan Rajagopalan, Ronald Karwoski, Maria Kokosi, David M. Hansell, Athol U. Wells

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Risk of incident active tuberculosis disease in patients treated with non-steroidal anti-inflammatory drugs: a population-based study

Chun-Wei Wu, Jiunn-Yih Wu, Meng-Tse Gabriel Lee, Chih-Cheng Lai, I-Lin Wu, Yi-Wen Tsai, Shy-Shin Chang, Chien-Chang Lee

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591)

Seher Raza Zaidi, Andrea M. Collins, Elena Mitsi, Jesús Reiné, Kayleigh Davies, Angela D Wright, Jessica Owugha, Richard Fitzgerald, Amitava Ganguli, Stephen B Gordon, Daniela Mulari Ferreira, Jamie Rylance

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Mechanical ventilation in idiopathic pulmonary fibrosis: a nationwide analysis of ventilator use, outcomes, and resource burden

Joshua J. Mooney, Karina Raimundo, Eunice Chang, Michael S. Broder

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Predicted body weight relationships for protective ventilation – unisex proposals from pre-term through to adult

Dion C. Martin, Glenn N. Richards

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Detection of ALK fusion transcripts in FFPE lung cancer samples by NanoString technology

Adriane F. Evangelista, Maicon F. Zanon, Adriana Cruvinel Carloni, Flávia E. de Paula, Mariana Andozia Morini, Maressa Ferreira-Neto, Iberê Cauduro Soares, Jose Elias Miziara, Pedro de Marchi, Cristovam Scapulatempo-Neto, Rui M. Reis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Evaluation of gene xpert for routine diagnosis of HIV-associated tuberculosis in Nigeria: A prospective cohort study

Maxwell Oluwole Akanbi, Chad Achenbach, Babafemi Taiwo, John Idoko, Agatha Ani, Yetunde Isa, Oche Agbaji, Christiana Ukoli, Patrick Akande, Mamoudou Maiga, Robert Leo Murphy

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Sarcoidosis as a rare cause for symmetrical giant bullous disease

Wolfgang Jungraithmayr, Elisa Leggeri, Walter Weder, Bart Vrugt

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

NRAMP1 and VDR gene polymorphisms in susceptibility to pulmonary tuberculosis among Andhra Pradesh population in India: a case–control study

Rooth Vasantha Medapati, Sridevi Suvvari, Sudhakar Godi, Paddaiah Gangisetti

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Health coaching to improve self-management and quality of life for low income patients with chronic obstructive pulmonary disease (COPD): protocol for a randomized controlled trial

Beatrice Huang, Rachel Willard-Grace, Denise De Vore, Jessica Wolf, Chris Chirinos, Stephanie Tsao, Danielle Hessler, George Su, David H. Thom

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Monitoring the electric activity of the diaphragm during noninvasive positive pressure ventilation: a case report

Fabia Diniz-Silva, Anna Miethke-Morais, Adriano M. Alencar, Henrique T. Moriya, Pedro Caruso, Eduardo L. V. Costa, Juliana C. Ferreira

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not

Catherine A. Spilling, Paul W. Jones, James W. Dodd, Thomas R. Barrick

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Three-dimensional substructure measurements for the differential diagnosis of ground glass nodules

Mingzheng Peng, Gang Yu, Chengzhong Zhang, Cuidi Li, Jinwu Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study

Kodai Kawamura, Kazuya Ichikado, Yuko Yasuda, Keisuke Anan, Moritaka Suga

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prevalence and associated risk factors of chronic bronchitis in First Nations people

Punam Pahwa, Chandima P. Karunanayake, Donna C. Rennie, Joshua A. Lawson, Vivian R. Ramsden, Kathleen McMullin, P. Jenny Gardipy, Judy MacDonald, Sylvia Abonyi, Jo-Ann Episkenew, James A. Dosman, the First Nations Lung Health Project Research Team

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Bacteraemia and fungaemia in cystic fibrosis patients with febrile pulmonary exacerbation: a prospective observational study

Joerg Grosse-Onnebrink, Florian Stehling, Eva Tschiedel, Margarete Olivier, Uwe Mellies, Rene Schmidt, Jan Buer, Peter-Micheal Rath, Joerg Steinmann

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia

Petra Um-Bergström, Jenny Hallberg, Per Thunqvist, Eva Berggren-Broström, Martin Anderson, Gunilla Adenfelt, Gunnar Lilja, Giovanni Ferrara, C. Magnus Sköld, Erik Melén

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Regulating autonomic nervous system homeostasis improves pulmonary function in rabbits with acute lung injury

Yan Liu, Tao Tao, Wenzhi Li, Yulong Bo

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Patient preferences for dry powder inhaler attributes in asthma and chronic obstructive pulmonary disease in France: a discrete choice experiment

Natalia Hawken, Saku Torvinen, Mohamed-Elmoctar Neine, Ikbel Amri, Mondher Toumi, Samuel Aballéa, Adam Plich, Nicolas Roche

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Monitoring clinical and microbiological evolution of a cystic fibrosis patient over 26 years: experience of a Brazilian CF Centre

Cassiana da Costa Ferreira Leite, Tania Wrobel Folescu, Mônica de Cássia Firmida, Renata Wrobel Folescu Cohen, Robson Souza Leão, Flávia Alvim Dutra de Freitas, Rodolpho Mattos Albano, Claudia Henrique da Costa, Elizabeth Andrade Marques

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Type 2 diabetes is associated with an increased prevalence of respiratory symptoms as compared to the general population

F. De Santi, G. Zoppini, F. Locatelli, E. Finocchio, V. Cappa, M. Dauriz, G. Verlato

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Analysis of long term CD4+CD25highCD127- T-reg cells kinetics in peripheral blood of lung transplant recipients

Davide Piloni, Monica Morosini, Sara Magni, Alice Balderacchi, Luigia Scudeller, Emanuela Cova, Tiberio Oggionni, Giulia Stella, Carmine Tinelli, Filippo Antonacci, Andrea Maria D’Armini, Federica Meloni

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Successful rescue combination of extracorporeal membrane oxygenation, high-frequency oscillatory ventilation and prone positioning for the management of severe methicillin-resistant Staphylococcus aureus pneumonia complicated by pneumothorax: a case report and literature review

Hangyong He, Hao Wang, Xuyan Li, Xiao Tang, Rui Wang, Bing Sun, Zhaohui Tong

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prognosis and longitudinal changes of physical activity in idiopathic pulmonary fibrosis

Thomas Bahmer, Anne-Marie Kirsten, Benjamin Waschki, Klaus F. Rabe, Helgo Magnussen, Detlef Kirsten, Marco Gramm, Simone Hummler, Eva Brunnemer, Michael Kreuter, Henrik Watz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation

Nan-Chun Wu, Fan-Ting Liao, Hao-min Cheng, Shih-Hsien Sung, Yu-Chun Yang, Jiun-Jr Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Air pollution exposure is associated with MRSA acquisition in young U.S. children with cystic fibrosis

Kevin J. Psoter, Anneclaire J. De Roos, Jon Wakefield, Jonathan D. Mayer, Margaret Rosenfeld

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, and sarcoidosis: more pathological findings in the same chest CT, or a single pathological pathway?

Fabiano Di Marco, Giuseppina Palumbo, Silvia Terraneo, Gianluca Imeri, Elena Lesma, Nicola Sverzellati, Angela Peron, Lorenzo Gualandri, Maria Paola Canevini, Stefano Centanni

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prognostic nomogram for inpatients with asthma exacerbation

Wakae Hasegawa, Yasuhiro Yamauchi, Hideo Yasunaga, Hideyuki Takeshima, Yukiyo Sakamoto, Taisuke Jo, Yusuke Sasabuchi, Hiroki Matsui, Kiyohide Fushimi, Takahide Nagase

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Diagnostic value of medical thoracoscopy in malignant pleural effusion

Yan-Bing Wu, Li-Li Xu, Xiao-Juan Wang, Zhen Wang, Jun Zhang, Zhao-Hui Tong, Huan-Zhong Shi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

S.N. Kehlet, C.L. Bager, N. Willumsen, B. Dasgupta, C. Brodmerkel, M. Curran, S. Brix, D.J. Leeming, M. A. Karsdal

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features

Yuhei Ito, Machiko Arita, Shogo Kumagai, Reoto Takei, Maki Noyama, Fumiaki Tokioka, Keisuke Nishimura, Takashi Koyama, Kenji Notohara, Tadashi Ishida

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between Charlson comorbidity index score and outcome in patients with stage IIIB-IV non-small cell lung cancer

Lei Zhao, Lai-Han Leung, Jing Wang, Huihui Li, Juanjuan Che, Lian Liu, Xiaojun Yao, Bangwei Cao

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

FEV1 and FVC and systemic inflammation in a spinal cord injury cohort

Jaime E. Hart, Rebekah Goldstein, Palak Walia, Merilee Teylan, Antonio Lazzari, Carlos G. Tun, Eric Garshick

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

A multi-center randomized, controlled, open-label trial evaluating the effects of eosinophil-guided corticosteroid-sparing therapy in hospitalised patients with COPD exacerbations – The CORTICO steroid reduction in COPD (CORTICO-COP) study protocol

Pradeesh Sivapalan, Mia Moberg, Josefin Eklöf, Julie Janner, Jørgen Vestbo, Rasmus Rude Laub, Andrea Browatzki, Karin Armbruster, Jon Torgny Wilcke, Niels Seersholm, Ulla Møller Weinreich, Ingrid Louise Titlestad, Helle Frost Andreassen, Charlotte Suppli Ulrik, Uffe Bødtger, Thyge Lynghøj Nielsen, Ejvind Frausing Hansen, Jens Ulrik Stæhr Jensen

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Effect of counselling during pulmonary rehabilitation on self-determined motivation towards physical activity in people with chronic obstructive pulmonary disease – protocol of a mixed methods study

Anne-Kathrin Rausch-Osthoff, Nicola Greco, Ariane Schwank, Swantje Beyer, David Gisi, Mandy Scheermesser, André Meichtry, Noriane Sievi, Thomas Hess, Markus Wirz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Volatile organic compounds in ventilated critical care patients: a systematic evaluation of cofactors

Tobias Hüppe, Dominik Lorenz, Mario Wachowiak, Felix Maurer, Andreas Meiser, Heinrich Groesdonk, Tobias Fink, Daniel I. Sessler, Sascha Kreuer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Influence of resting lung diffusion on exercise capacity in patients with COPD

Mehrdad Behnia, Courtney Wheatley, Alberto Avolio, Bruce Johnson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reference values of fractional excretion of exhaled nitric oxide among non-smokers and current smokers

Kjell Torén, Nicola Murgia, Linus Schiöler, Björn Bake, Anna-Carin Olin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reference Equations for the Six-Minute Walk Distance in the Healthy Chinese Han Population, Aged 18–30 Years

He Zou, Jia Zhang, Xiaoshu Chen, Yi Wang, Wei Lin, Jianfeng Lin, Hao Chen, Jingye Pan

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Propensity score analysis of lung cancer risk in a population with high prevalence of non-smoking related lung cancer

Kuei-Feng Lin, Hsiu-Fu Wu, Wei-Chun Huang, Pei-Ling Tang, Ming-Ting Wu, Fu-Zong Wu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pulmonary challenge with carbon nanoparticles induces a dose-dependent increase in circulating leukocytes in healthy males

Marieke Berger, Johannes D. de Boer, René Lutter, Michiel Makkee, Peter J. Sterk, Elles M. Kemper, Jaring S. van der Zee

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, phase II trial

Jürgen Behr, Petra Neuser, Antje Prasse, Michael Kreuter, Klaus Rabe, Carmen Schade-Brittinger, Jasmin Wagner, Andreas Günther

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Clinical and radiological characteristics of patients with late-onset severe restrictive lung defect after hematopoietic stem cell transplantation

Ho Namkoong, Makoto Ishii, Takehiko Mori, Hiroaki Sugiura, Sadatomo Tasaka, Masatoshi Sakurai, Yuya Koda, Jun Kato, Naoki Hasegawa, Shinichiro Okamoto, Tomoko Betsuyaku

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Unmet needs in the treatment of idiopathic pulmonary fibrosis―insights from patient chart review in five European countries

Toby M. Maher, Maria Molina-Molina, Anne-Marie Russell, Francesco Bonella, Stéphane Jouneau, Elena Ripamonti, Judit Axmann, Carlo Vancheri

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The effect of sedation and/or analgesia as rescue treatment during noninvasive positive pressure ventilation in the patients with Interface intolerance after Extubation

Yue-Nan Ni, Ting Wang, He Yu, Bin-Miao Liang, Zong-An Liang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A qualitative study to identify parents’ perceptions of and barriers to asthma management in children from South Asian and White British families

Monica Lakhanpaul, Lorraine Culley, Noelle Robertson, Deborah Bird, Nicky Hudson, Narynder Johal, Melanie McFeeters, Emma Angell, Charlotte Hamlyn-Williams, Nadine Abbas, Logan Manikam, Mark Johnson

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

The efficacy of initial ventilation strategy for adult immunocompromised patients with severe acute hypoxemic respiratory failure: study protocol for a multicentre randomized controlled trial (VENIM)

Tao Wang, Gang Liu, Kun He, Xin Lu, Xianquan Liang, Meng Wang, Rong Zhu, Zongru Li, Feng Chen, Jun Ke, Qingming Lin, Chuanyun Qian, Bo Li, Jie Wei, Jingjun Lv, Li Li, Yanxia Gao, Guofeng Wu, Xiaohong Yu, Weiqin Wei, Ying Deng, Fengping Wang, Hong Zhang, Yun Zheng, Hong Zhan, Jinli Liao, Yingping Tian, Dongqi Yao, Jingsong Zhang, Xufeng Chen, Lishan Yang, Jiali Wu, Yanfen Chai, Songtao Shou, Muming Yu, Xudong Xiang, Dongshan Zhang, Fengying Chen, Xiufeng Xie, Yong Li, Bo Wang, Wenzhong Zhang, Yongli Miao, Michael Eddleston, Jianqiang He, Yong Ma, Shengyong Xu, Yi Li, Huadong Zhu, Xuezhong Yu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between dementia and discharge status in patients hospitalized with pneumonia

Taisuke Jo, Hideo Yasunaga, Yusuke Sasabuchi, Nobuaki Michihata, Kojiro Morita, Yasuhiro Yamauchi, Wakae Hasegawa, Hideyuki Takeshima, Yukiyo Sakamoto, Hiroki Matsui, Kiyohide Fushimi, Takahide Nagase

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation

Pablo Cruces, Sebastián González-Dambrauskas, Julio Quilodrán, Jorge Valenzuela, Javier Martínez, Natalia Rivero, Pablo Arias, Franco Díaz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effectiveness of pulmonary rehabilitation in patients with interstitial lung disease of different etiology: a multicenter prospective study

Roberto Tonelli, Elisabetta Cocconcelli, Barbara Lanini, Isabella Romagnoli, Fabio Florini, Ivana Castaniere, Dario Andrisani, Stefania Cerri, Fabrizio Luppi, Riccardo Fantini, Alessandro Marchioni, Bianca Beghè, Francesco Gigliotti, Enrico M. Clini

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the Commonwealth of Independent States: rationale and design of the CORE study

Yuriy Feshchenko, Liudmyla Iashyna, Damilya Nugmanova, Olga Gyrina, Maryna Polianska, Alexander Markov, Maryna Moibenko, Janina Makarova, Luqman Tariq, Marcelo Horacio S. Pereira, Eljan Mammadbayov, Irada Akhundova, Averyan Vasylyev

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The value of repeat radial-probe endobronchial ultrasound-guided transbronchial biopsy after initial non-diagnostic results in patients with peripheral pulmonary lesions

Chun-Ta Huang, Yi-Ju Tsai, Chao-Chi Ho, Chong-Jen Yu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers

Yunguan Wang, Jaswanth Yella, Jing Chen, Francis X. McCormack, Satish K. Madala, Anil G. Jegga

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Clinical effects of direct hemoperfusion using a polymyxin B-immobilized fiber column in clinically amyopathic dermatomyositis-associated rapidly progressive interstitial pneumonias

Hiroko Okabayashi, Hidenori Ichiyasu, Sayuri Hirooka, Kimitaka Akaike, Keisuke Kojima, Takayuki Jodai, Yasumiko Sakamoto, Hideharu Ideguchi, Shohei Hamada, Chieko Yoshida, Susumu Hirosako, Shinichiro Okamoto, Hirotsugu Kohrogi

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Successful transition from Treprostinil to Selexipag in patient with severe pulmonary arterial hypertension

Asuka Furukawa, Yuichi Tamura, Hiroya Iwahori, Masato Goto, Narutaka Ohashi, Teruo Okabe, Akio Kawamura

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Knowledge gaps in patients with COPD and their proxies

Nienke Nakken, Daisy J. A. Janssen, Esther H. A. van den Bogaart, Jean W. M. Muris, Jan H. Vercoulen, Frank L. Custers, Gerben P. Bootsma, Michiel H. M. Gronenschild, Emiel F. M. Wouters, Martijn A. Spruit

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A rise in mean platelet volume during hospitalization for community-acquired pneumonia predicts poor prognosis: a retrospective observational cohort study

Oleg Gorelik, Irma Tzur, Dana Barchel, Dorit Almoznino-Sarafian, Muhareb Swarka, Ilia Beberashvili, Leonid Feldman, Natan Cohen, Shimon Izhakian

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Antibiotic perturbation of mixed-strain Pseudomonas aeruginosa infection in patients with cystic fibrosis

Anna S. Tai, Laura J. Sherrard, Timothy J. Kidd, Kay A. Ramsay, Cameron Buckley, Melanie Syrmis, Keith Grimwood, Scott C. Bell, David M. Whiley

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Neurally Adjusted Ventilatory Assist (NAVA) or Pressure Support Ventilation (PSV) during spontaneous breathing trials in critically ill patients: a crossover trial

Juliana C. Ferreira, Fabia Diniz-Silva, Henrique T. Moriya, Adriano M. Alencar, Marcelo B. P. Amato, Carlos R. R. Carvalho

01.12.2017 | Study protocol | Ausgabe 1/2017 Open Access

COPD online-rehabilitation versus conventional COPD rehabilitation – rationale and design for a multicenter randomized controlled trial study protocol (CORe trial)

Henrik Hansen, Theresa Bieler, Nina Beyer, Nina Godtfredsen, Thomas Kallemose, Anne Frølich

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Analytical performance of Envisia: a genomic classifier for usual interstitial pneumonia

Yoonha Choi, Jiayi Lu, Zhanzhi Hu, Daniel G. Pankratz, Huimin Jiang, Manqiu Cao, Cristina Marchisano, Jennifer Huiras, Grazyna Fedorowicz, Mei G. Wong, Jessica R. Anderson, Edward Y. Tom, Joshua Babiarz, Urooj Imtiaz, Neil M. Barth, P. Sean Walsh, Giulia C. Kennedy, Jing Huang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Can high-flow nasal cannula reduce the rate of reintubation in adult patients after extubation? A meta-analysis

Yue-Nan Ni, Jian Luo, He Yu, Dan Liu, Bin-Miao Liang, Rong Yao, Zong-An Liang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Efficacy and safety of nasal high-flow oxygen in COPD patients

Helene Vogelsinger, Michael Halank, Silke Braun, Heinrike Wilkens, Thomas Geiser, Sebastian Ott, Armin Stucki, Christian M. Kaehler

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case–control study

Changjiang Xue, Na Wu, Xue Li, Meihua Qiu, Xuqin Du, Qiao Ye

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Combined effects of leaks, respiratory system properties and upper airway patency on the performance of home ventilators: a bench study

Kaixian Zhu, Claudio Rabec, Jésus Gonzalez-Bermejo, Sébastien Hardy, Sami Aouf, Pierre Escourrou, Gabriel Roisman

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Long-term prognosis of chronic cough: a prospective, observational cohort study

Heikki O. Koskela, Anne M. Lätti, Minna K. Purokivi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Clinical significance of cigarette smoking and dust exposure in pulmonary alveolar proteinosis: a Korean national survey

Ji An Hwang, Joo Han Song, Jung Hoon Kim, Man Pyo Chung, Dong Soon Kim, Jin Woo Song, Young Whan Kim, Sun Mi Choi, Seung Ick Cha, Soo Taek Uh, Choon-Sik Park, Sung Hwan Jeong, Yong Bum Park, Hong Lyeol Lee, Jong Wook Shin, Eun Joo Lee, Yangjin Jegal, Hyun Kyung Lee, Jong Sun Park, Moo Suk Park

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of sivelestat sodium in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of randomized controlled trials

Shenglan Pu, Daoxin Wang, Daishun Liu, Yan Zhao, Di Qi, Jing He, Guoqi Zhou

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Elevated Aspergillus-specific antibody levels among HIV infected Ugandans with pulmonary tuberculosis

Richard Kwizera, Rosalind Parkes-Ratanshi, Iain D. Page, Christine Sekaggya-Wiltshire, Joseph Musaazi, Jan Fehr, Barbara Castelnuovo, Andrew Kambugu, David W. Denning

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Detection of pathogens by real-time PCR in adult patients with acute exacerbation of bronchial asthma

Yutaka Yoshii, Kenichiro Shimizu, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hironori Uruga, Shigeo Hanada, Hiroshi Wakui, Shunsuke Minagawa, Hiromichi Hara, Takanori Numata, Keisuke Saito, Jun Araya, Katsutoshi Nakayama, Kazuma Kishi, Kazuyoshi Kuwano

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Medical thoracoscopy for exudative pleural effusion: an eight-year experience from a country with a young population

Merlin Thomas, Wanis H. Ibrahim, Tasleem Raza, Kamran Mushtaq, Adeel Arshad, Mushtaq Ahmed, Salma Taha, Saber Al Sarafandi, Hanfa Karim, Hisham A. Abdul-sattar

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Tracking dyspnea up to supplemental oxygen prescription among patients with pulmonary fibrosis

Amy L. Olson, Bridget Graney, Susan Baird, Tara Churney, Kaitlin Fier, Marjorie Korn, Mark McCormick, David Sprunger, Thomas Vierzba, Frederick S. Wamboldt, Jeffrey J. Swigris

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Physician perspectives on the burden and management of asthma in six countries: The Global Asthma Physician Survey (GAPS)

Kenneth R. Chapman, David Hinds, Peter Piazza, Chantal Raherison, Michael Gibbs, Timm Greulich, Kenneth Gaalswyk, Jiangtao Lin, Mitsuru Adachi, Kourtney J. Davis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Physical activity and activity space in patients with pulmonary fibrosis not prescribed supplemental oxygen

Elisabeth Dowling Root, Bridget Graney, Susan Baird, Tara Churney, Kailtin Fier, Majorie Korn, Mark McCormic, David Sprunger, Tomas Vierzba, Frederick S. Wamboldt, Jeffery J. Swigris

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pleural plaques in lung cancer screening by low-dose computed tomography: prevalence, association with lung cancer and mortality

Mario Silva, Nicola Sverzellati, Davide Colombi, Gianluca Milanese, Carlo La Vecchia, Carlotta Galeone, Alfonso Marchianò, Ugo Pastorino

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Fever after bronchoscopy: serum procalcitonin enables early diagnosis of post-interventional bacterial infection

Klaus Hackner, Waltraud Riegler, Sabin Handzhiev, Rosemarie Bauer, Jan Veres, Manuela Speiser, Karin Meisinger, Peter Errhalt

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort

Paula Duarte de Oliveira, Fernando César Wehrmeister, Bernardo Lessa Horta, Rogelio Pérez-Padilla, Giovanny Vinícius Araújo de França, Denise P. Gigante, Fernando C. Barros, Ken K. Ong, Emanuella De Lucia Rolfe, Ana Maria Baptista Menezes

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

Roy H. E. Cloots, Selvakumari Sankaranarayanan, Matthew E. Poynter, Els Terwindt, Paul van Dijk, Wouter H. Lamers, S. Eleonore Köhler

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Tobacco-smoking induced GPR15-expressing T cells in blood do not indicate pulmonary damage

Mario Bauer, Beate Fink, Hans-Jürgen Seyfarth, Hubert Wirtz, Armin Frille

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Antibiotic duration and changes in FEV1 are not associated with time until next exacerbation in adult cystic fibrosis: a single center study

Julia C. Espel, Hannah L. Palac, Joanne F. Cullina, Alexandria P. Clarke, Susanna A. McColley, Michelle H. Prickett, Manu Jain

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Different effects of cardiac and diaphragm function assessed by ultrasound on extubation outcomes in difficult-to-wean patients: a cohort study

Ling Luo, Yidan Li, Xiukai Chen, Bing Sun, Wenxiong Li, Wei Gu, Shuo Wang, Song Zhao, Yanwei Lv, Mulei Chen, Jingen Xia, Feng Sui, Xue Mei, Huanzhong Shi, Zhaohui Tong

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

An implantable pump Lenus pro® in the treatment of pulmonary arterial hypertension with intravenous treprostinil

Marcin Kurzyna, Katarzyna Małaczyńska-Rajpold, Andrzej Koteja, Agnieszka Pawlak, Łukasz Chrzanowski, Michał Furdal, Zbigniew Gąsior, Wojciech Jacheć, Bożena Sobkowicz, Justyna Norwa, Tatiana Mularek-Kubzdela, Adam Torbicki

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Regulation of TERRA on telomeric and mitochondrial functions in IPF pathogenesis

Yulin Gao, Jinjin Zhang, Yuxia Liu, Songzi Zhang, Youlei Wang, Bo Liu, Huizhu Liu, Rongrong Li, Changjun Lv, Xiaodong Song

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study

Diana J. Leeming, Inger Byrjalsen, Jannie M. B. Sand, Asger R. Bihlet, Peter Lange, Ruth Thal-Singer, Bruce E. Miller, Morten A. Karsdal, Jørgen Vestbo, The Evaluation of COPD Longitudinally to Identify Surrogate Endpoints (ECLIPSE) study investigators

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in major depression: a observational and retrospective study on 703 subjects

Matthieu Hein, Jean-Pol Lanquart, Gwenolé Loas, Philippe Hubain, Paul Linkowski

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Development and validation of a preoperative prognostic index independent of TNM stage in resected non-small cell lung cancer

Shogo Kumagai, Satoshi Marumo, Machiko Arita, Keiji Yamanashi, Ryota Sumitomo, Yosuke Otake, Tsuyoshi Shoji, Motonari Fukui, Toshiro Katayama, Norihito Okumura, Cheng-Long Huang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The association of N-terminal pro-brain-type natriuretic peptide with hemodynamics and functional capacity in therapy-naive precapillary pulmonary hypertension: results from a cohort study

T. M. Berghaus, J. Kutsch, C. Faul, W. von Scheidt, M. Schwaiblmair

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The pleural fluid lactate dehydrogenase/adenosine deaminase ratio differentiates between tuberculous and parapneumonic pleural effusions

Jinlin Wang, Jun Liu, Xiaohong Xie, Panxiao Shen, Jianxing He, Yunxiang Zeng

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effects of treatment changes on asthma phenotype prevalence and airway neutrophil function

Collin R. Brooks, Christine J. Van Dalen, Elizabeth Harding, Ian F. Hermans, Jeroen Douwes

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The lung microbiome in patients with pneumocystosis

J. Kehrmann, B. Veckollari, D. Schmidt, O. Schildgen, V. Schildgen, N. Wagner, M. Zeschnigk, L. Klein-Hitpass, O. Witzke, J. Buer, J. Steinmann

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study

Yuriy Feshchenko, Liudmyla Iashyna, Damilya Nugmanova, Olga Gyrina, Maryna Polianska, Alexander Markov, Maryna Moibenko, Janina Makarova, Luqman Tariq, Marcelo Horacio S. Pereira, Eljan Mammadbayov, Irada Akhundova, Averyan Vasylyev

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: Effect of inhaled corticosteroid particle size on asthma efficacy and safety outcomes: a systematic literature review and meta-analysis

Céline El Baou, Rachael L. DiSantostefano, Rafael Alfonso-Cristancho, Elizabeth A. Suarez, David Stempel, Mark L. Everard, Neil Barnes

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Case report: continued treatment with alectinib is possible for patients with lung adenocarcinoma with drug-induced interstitial lung disease

Tatsuya Nitawaki, Yoshihiko Sakata, Kodai Kawamura, Kazuya Ichikado

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Identification of the lipid biomarkers from plasma in idiopathic pulmonary fibrosis by Lipidomics

Feng Yan, Zhensong Wen, Rui Wang, Wenling Luo, Yufeng Du, Wenjun Wang, Xianyang Chen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Feasibility of tissue re-biopsy in non-small cell lung cancers resistant to previous epidermal growth factor receptor tyrosine kinase inhibitor therapies

Sakurako Uozu, Kazuyoshi Imaizumi, Teppei Yamaguchi, Yasuhiro Goto, Kenji Kawada, Tomoyuki Minezawa, Takuya Okamura, Ken Akao, Masamichi Hayashi, Sumito Isogai, Mitsushi Okazawa, Naozumi Hashimoto, Yoshinori Hasegawa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A simple prediction tool for inhaled corticosteroid response in asthmatic children

Yi-Fan Wu, Ming-Wei Su, Bor-Luen Chiang, Yao-Hsu Yang, Ching-Hui Tsai, Yungling L. Lee

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The incidence and risk factors of asymptomatic primary spontaneous pneumothorax detected during health check-ups

Akihisa Mitani, Yukichika Hakamata, Megumi Hosoi, Masafumi Horie, Yoko Murano, Akira Saito, Shintaro Yanagimoto, Shoji Tsuji, Kazuhiko Yamamoto, Takahide Nagase

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of rapid investigation clinic on timeliness of lung cancer diagnosis and treatment

Nicole Ezer, Asma Navasakulpong, Kevin Schwartzman, Linda Ofiara, Anne V. Gonzalez

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Access to affordable medicines and diagnostic tests for asthma and COPD in sub Saharan Africa: the Ugandan perspective

Davis Kibirige, Leaticia Kampiire, David Atuhe, Raymond Mwebaze, Winceslaus Katagira, Winters Muttamba, Rebecca Nantanda, William Worodria, Bruce Kirenga

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Diagnostic value of interleukins for tuberculous pleural effusion: a systematic review and meta-analysis

Ni Zeng, Chun Wan, Jiangyu Qin, Yanqiu Wu, Ting Yang, Yongchun Shen, Fuqiang Wen, Lei Chen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The impacts of baseline ventilator parameters on hospital mortality in acute respiratory distress syndrome treated with venovenous extracorporeal membrane oxygenation: a retrospective cohort study

Meng-Yu Wu, Yu-Sheng Chang, Chung-Chi Huang, Tzu-I Wu, Pyng-Jing Lin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The role of sleepiness on arterial stiffness improvement after CPAP therapy in males with obstructive sleep apnea: a prospective cohort study

Maria Alexandra Mineiro, Pedro Marques da Silva, Marta Alves, Ana Luísa Papoila, Maria João Marques Gomes, João Cardoso

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prevalence and etiologies of pulmonary hypertension in Africa: a systematic review and meta-analysis

Jean Joel Bigna, Jean Jacques Noubiap, Jobert Richie Nansseu, Leopold Ndemnge Aminde

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Virtual bronchoscopic navigation without X-ray fluoroscopy to diagnose peripheral pulmonary lesions: a randomized trial

Fumihiro Asano, Takashi Ishida, Naofumi Shinagawa, Noriaki Sukoh, Masaki Anzai, Kenya Kanazawa, Akifumi Tsuzuku, Satoshi Morita

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Multiple breath washout testing in adults with pulmonary disease and healthy controls – can fewer measurements eventually be more?

Frederik Trinkmann, Johannes Götzmann, Daniel Saur, Michele Schroeter, Katharina Roth, Ksenija Stach, Martin Borggrefe, Joachim Saur, Ibrahim Akin, Julia D. Michels

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Dosimetrically administered nebulized morphine for breathlessness in very severe chronic obstructive pulmonary disease: a randomized, controlled trial

Piotr Janowiak, Małgorzata Krajnik, Zygmunt Podolec, Tomasz Bandurski, Iwona Damps-Konstańska, Piotr Sobański, David C. Currow, Ewa Jassem

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Estimating prevalence of chronic obstructive pulmonary disease in the Southern Cone of Latin America: how different spirometric criteria may affect disease burden and health policies

Edgardo Sobrino, Vilma E. Irazola, Laura Gutierrez, Chung-Shiuan Chen, Fernando Lanas, Matías Calandrelli, Jacqueline Ponzo, Nora Mores, Pamela Serón, Allison Lee, Jiang He, Adolfo L. Rubinstein

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pulmonary exacerbations and clinical outcomes in a longitudinal cohort of infants and preschool children with cystic fibrosis

Jordana E. Hoppe, Brandie D. Wagner, Scott D. Sagel, Frank J. Accurso, Edith T. Zemanick

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Gene expression analysis in asthma using a targeted multiplex array

Christopher D. Pascoe, Ma’en Obeidat, Bryna A. Arsenault, Yunlong Nie, Stephanie Warner, Dorota Stefanowicz, Samuel J. Wadsworth, Jeremy A. Hirota, S. Jasemine Yang, Delbert R. Dorscheid, Chris Carlsten, Tillie L. Hackett, Chun Y. Seow, Peter D. Paré

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between high-density lipoprotein cholesterol level and pulmonary function in healthy Korean adolescents: the JS high school study

Ji Hye Park, Seyeon Mun, Dong Phil Choi, Joo Young Lee, Hyeon Chang Kim

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway

Di Gui, Zhimin Cui, Lin Zhang, Chang Yu, Dan Yao, Min Xu, Mayun Chen, Peiliang Wu, Guoping Li, Liangxing Wang, Xiaoying Huang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Determinants of excessive daytime sleepiness in two First Nation communities

Ina van der Spuy, Chandima P. Karunanayake, James A. Dosman, Kathleen McMullin, Gaungming Zhao, Sylvia Abonyi, Donna C. Rennie, Joshua Lawson, Shelley Kirychuk, Judith MacDonald, Laurie Jimmy, Niels Koehncke, Vivian R. Ramsden, Mark Fenton, Gregory P. Marchildon, Malcolm King, Punam Pahwa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: a systematic meta-analysis

Yanting Zhu, Xin Yan, Cui Zhai, Lan Yang, Manxiang Li

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

Jingzhu Lv, Xiaoyan He, Hongtao Wang, Zhaohua Wang, Gabriel T. Kelly, Xiaojing Wang, Yin Chen, Ting Wang, Zhongqing Qian

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Napsin A levels in epithelial lining fluid as a diagnostic biomarker of primary lung adenocarcinoma

Akifumi Uchida, Takuya Samukawa, Tomohiro Kumamoto, Masahiro Ohshige, Kazuhito Hatanaka, Yoshihiro Nakamura, Keiko Mizuno, Ikkou Higashimoto, Masami Sato, Hiromasa Inoue

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Antibiotics for treatment of acute exacerbation of chronic obstructive pulmonary disease: a network meta-analysis

Hai-Lin Zhang, Min Tan, Ai-Min Qiu, Zhang Tao, Chang-Hui Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

NKX2–1 expression as a prognostic marker in early-stage non-small-cell lung cancer

Jorge Moisés, Alfons Navarro, Sandra Santasusagna, Nuria Viñolas, Laureano Molins, José Ramirez, Jeisson Osorio, Adela Saco, Joan Josep Castellano, Carmen Muñoz, Sara Morales, Mariano Monzó, Ramón María Marrades

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of chronic Pseudomonas aeruginosa infection on health-related quality of life in Mycobacterium avium complex lung disease

Hirofumi Kamata, Takanori Asakura, Shoji Suzuki, Ho Namkoong, Kazuma Yagi, Yohei Funatsu, Satoshi Okamori, Shunsuke Uno, Yoshifumi Uwamino, Hiroshi Fujiwara, Tomoyasu Nishimura, Makoto Ishii, Tomoko Betsuyaku, Naoki Hasegawa

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Long non-coding RNA MALAT1 protects preterm infants with bronchopulmonary dysplasia by inhibiting cell apoptosis

Cheng Cai, Jiajun Qiu, Gang Qiu, Yihuan Chen, Zhijun Song, Juan Li, Xiaohui Gong

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Potential benefit of bosentan therapy in borderline or less severe pulmonary hypertension secondary to idiopathic pulmonary fibrosis—an interim analysis of results from a prospective, single-center, randomized, parallel-group study

Yosuke Tanaka, Mitsunori Hino, Akihiko Gemma

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients with acute respiratory failure: a systematic review and meta-analysis of randomized controlled trials

Youfeng Zhu, Haiyan Yin, Rui Zhang, Jianrui Wei

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Delay in diagnosis of pulmonary tuberculosis in low-and middle-income settings: systematic review and meta-analysis

Fentabil Getnet, Meaza Demissie, Nega Assefa, Bizatu Mengistie, Alemayehu Worku

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

A case of herbicide-induced acute fibrinous and organizing pneumonia?

Shengsong Chen, Hong Zhou, Lingling Yu, Bo Tong, Zuke Xiao, Sisi Fan

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome: validation in US and Korean cohorts

Jinkyeong Park, Maria Pabon, Augustine M. K. Choi, Ilias I. Siempos, Laura E. Fredenburgh, Rebecca M. Baron, Kyeongman Jeon, Chi Ryang Chung, Jeong Hoon Yang, Chi-Min Park, Gee Young Suh

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between ATM gene polymorphisms, lung cancer susceptibility and radiation-induced pneumonitis: a meta-analysis

Zhipeng Yan, Xiang Tong, Yao Ma, Sitong Liu, Lingjing Yang, Xin Yang, Xue Yang, Min Bai, Hong Fan

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial

Mario H. Vargas, Rosangela Del-Razo-Rodríguez, Amando López-García, José Luis Lezana-Fernández, Jaime Chávez, María E. Y. Furuya, Juan Carlos Marín-Santana

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Airway administration of corticosteroids for prevention of bronchopulmonary dysplasia in premature infants: a meta-analysis with trial sequential analysis

Zhi-Qun Zhang, Ying Zhong, Xian-Mei Huang, Li-Zhong Du

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Rates and risk factors associated with hospitalization for pneumonia with ICU admission among adults

Aaron D. Storms, Jufu Chen, Lisa A. Jackson, James D. Nordin, Allison L. Naleway, Jason M. Glanz, Steven J. Jacobsen, Eric S. Weintraub, Nicola P. Klein, Paul M. Gargiullo, Alicia M. Fry

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A cluster analysis of chronic obstructive pulmonary disease in dusty areas cohort identified three subgroups

Suhyun Kim, Myoung-Nam Lim, Yoonki Hong, Seon-Sook Han, Seung-Joon Lee, Woo Jin Kim

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association analysis of ILVBL gene polymorphisms with aspirin-exacerbated respiratory disease in asthma

Hun Soo Chang, Jong Sook Park, Ho Sung Lee, Jiwon Lyu, Ji-Hye Son, Inseon S. Choi, Hyoung Doo Shin, Choon-Sik Park

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Legionella pneumonia due to non-Legionella pneumophila serogroup 1: usefulness of the six-point scoring system

Akihiro Ito, Tadashi Ishida, Yasuyoshi Washio, Akio Yamazaki, Hiromasa Tachibana

01.12.2017 | Debate | Ausgabe 1/2017 Open Access

Lung ultrasonography to diagnose community-acquired pneumonia in children

Nicola Principi, Andrea Esposito, Caterina Giannitto, Susanna Esposito

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Implication of species change of Nontuberculous Mycobacteria during or after treatment

Jong Sik Lee, Jong Hyuk Lee, Soon Ho Yoon, Taek Soo Kim, Moon-Woo Seong, Sung Koo Han, Jae-Joon Yim

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study

Bing Liu, Zhaohui Wan, Baowei Sheng, Yong Lin, Tian Fu, Qingdi Zeng, Congcong Qi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association of physical activity with lung function in lung-healthy German adults: results from the KORA FF4 study

Agnes Luzak, Stefan Karrasch, Barbara Thorand, Dennis Nowak, Rolf Holle, Annette Peters, Holger Schulz

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Riociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study

Vallerie V. McLaughlin, Pavel Jansa, Jens E. Nielsen-Kudsk, Michael Halank, Gérald Simonneau, Ekkehard Grünig, Silvia Ulrich, Stephan Rosenkranz, Miguel A. Gómez Sánchez, Tomás Pulido, Joanna Pepke-Zaba, Joan Albert Barberá, Marius M. Hoeper, Jean-Luc Vachiéry, Irene Lang, Francine Carvalho, Christian Meier, Katharina Mueller, Sylvia Nikkho, Andrea M. D’Armini

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Case report: atypical presentation of vancomycin induced DRESS syndrome: a case report and review of the literature

Olivia Wilcox, Mohamed Hassanein, John Armstrong, Nader Kassis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Plasma levels of alarmin HNPs 1–3 associate with lung dysfunction after cardiac surgery in children

XiWang Liu, QiXing Chen, YuJia Luo, YaoQin Hu, DengMing Lai, XiaoLe Zhang, XiangHong Zhang, JianGen Yu, XiangMing Fang, Qiang Shu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Adjunctive corticosteroid therapy for inpatients with Mycoplasma pneumoniae pneumonia

Masato Tashiro, Kiyohide Fushimi, Kei Kawano, Takahiro Takazono, Tomomi Saijo, Kazuko Yamamoto, Shintaro Kurihara, Yoshifumi Imamura, Taiga Miyazaki, Katsunori Yanagihara, Hiroshi Mukae, Koichi Izumikawa

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