Ausgabe 1/2010
Inhalt (98 Artikel)
Ryanodine receptors contribute to the induction of nociceptive input-evoked long-term potentiation in the rat spinal cord slice
Long-Zhen Cheng, Ning Lü, Yu-Qiu Zhang, Zhi-Qi Zhao
Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model
Liu Si Lan, Yang Jian Ping, Wang Li Na, Jiang Miao, Qiu Qiao Cheng, Ma Zhen Ni, Liu Lei, Li Cai Fang, Ren Chun Guang, Zhou Jin, Li Wei
Effects of Parecoxib and Fentanyl on nociception-induced cortical activity
Yuan-Zhi Peng, Xiao-Xi Li, Ying-Wei Wang
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity
Clive Gentry, Natalie Stoakley, David A Andersson, Stuart Bevan
Regulation of AMPA receptors in spinal nociception
Yun Wang, Jing Wu, Zhiguo Wu, Qing Lin, Yun Yue, Li Fang
KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy
Vasiliki Zoga, Takashi Kawano, Mei-Ying Liang, Martin Bienengraeber, Dorothee Weihrauch, Bruce McCallum, Geza Gemes, Quinn Hogan, Constantine Sarantopoulos
Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli
Sukdeb Datta, Koel Chatterjee, Robert H Kline IV, Ronald G Wiley
Trigeminal injury causes kappa opioid-dependent allodynic, glial and immune cell responses in mice
Megumi Aita, Margaret R Byers, Charles Chavkin, Mei Xu
Alteration of primary afferent activity following inferior alveolar nerve transection in rats
Kazuharu Nakagawa, Mamoru Takeda, Yoshiyuki Tsuboi, Masahiro Kondo, Junichi Kitagawa, Shigeji Matsumoto, Azusa Kobayashi, Barry J Sessle, Masamichi Shinoda, Koichi Iwata
Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats
Jeong S Han, Hita Adwanikar, Zhen Li, Guangchen Ji, Volker Neugebauer
Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors
Xiangqi Li, Peyman Sahbaie, Ming Zheng, Jennifer Ritchie, Gary Peltz, Jeffrey S Mogil, J David Clark
Kinin B1 receptors contributes to acute pain following minor surgery in humans
May Hamza, Xiao-Min Wang, Albert Adam, Jaime S Brahim, Janet S Rowan, Gilberto N Carmona, Raymond A Dionne
Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice
Yong Chen, Michael K Boettger, Andreas Reif, Angelika Schmitt, Nurcan Üçeyler, Claudia Sommer
TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats
Steve McGaraughty, Katharine L Chu, Richard J Perner, Stan DiDomenico, Michael E Kort, Philip R Kym
Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice
Lauren E Ta, Allan J Bieber, Susan M Carlton, Charles L Loprinzi, Philip A Low, Anthony J Windebank
Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
Cory C Toth, Nicole M Jedrzejewski, Connie L Ellis, William H Frey II
Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats
João Walter S Silveira, Quintino M Dias, Elaine A Del Bel, Wiliam A Prado
An improved behavioural assay demonstrates that ultrasound vocalizations constitute a reliable indicator of chronic cancer pain and neuropathic pain
Martina Kurejova, Ulrike Nattenmüller, Ullrich Hildebrandt, Deepitha Selvaraj, Sebastian Stösser, Rohini Kuner
Spinal microglial motility is independent of neuronal activity and plasticity in adult mice
Tao Chen, Kohei Koga, Xiang-Yao Li, Min Zhuo
Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation
Nathaniel A Sowa, Meagen K Voss, Mark J Zylka
Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior
Sacha A Malin, Derek C Molliver
Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats
Theresa-Alexandra M Mattioli, Brian Milne, Catherine M Cahill
Inflammation and nerve injury induce expression of pancreatitis-associated protein-II in primary sensory neurons
Shao-Qiu He, Jun-Ru Yao, Fang-Xiong Zhang, Qiong Wang, Lan Bao, Xu Zhang
Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel NaV1.7 produce distinct pain disorders
Xiaoyang Cheng, Sulayman D Dib-Hajj, Lynda Tyrrell, Dowain A Wright, Tanya Z Fischer, Stephen G Waxman
Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons
Stefan K Georgiev, Hidemasa Furue, Hiroshi Baba, Tatsuro Kohno
NR2 subunits and NMDA receptors on lamina II inhibitory and excitatory interneurons of the mouse dorsal horn
Hiroaki Shiokawa, Edward J Kaftan, Amy B MacDermott, Chi-Kun Tong
A key role of the basal ganglia in pain and analgesia - insights gained through human functional imaging
David Borsook, Jaymin Upadhyay, Eric H Chudler, Lino Becerra
p38 mediates mechanical allodynia in a mouse model of type 2 diabetes
Hsinlin T Cheng, Jacqueline R Dauch, Sang Su Oh, John M Hayes, Yu Hong, Eva L Feldman
Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P
Ewan St John Smith, Gregory RC Blass, Gary R Lewin, Thomas J Park
In vivo patch-clamp analysis of response properties of rat primary somatosensory cortical neurons responding to noxious stimulation of the facial skin
Mamoru Takeda, Masayuki Takahashi, Masanori Nasu, Shigeji Matsumoto
Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture
Lucy Vulchanova, Daniel J Schuster, Lalitha R Belur, Maureen S Riedl, Kelly M Podetz-Pedersen, Kelley F Kitto, George L Wilcox, R Scott McIvor, Carolyn A Fairbanks
The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation
Arian Mobascher, Juergen Brinkmeyer, Holger Thiele, Mohammad R Toliat, Michael Steffens, Tracy Warbrick, Francesco Musso, Hans-Joerg Wittsack, Andreas Saleh, Alfons Schnitzler, Georg Winterer
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism
Pavel Gris, Josee Gauthier, Philip Cheng, Dustin G Gibson, Denis Gris, Oskar Laur, John Pierson, Sean Wentworth, Andrea G Nackley, William Maixner, Luda Diatchenko
Hypolocomotion, asymmetrically directed behaviors (licking, lifting, flinching, and shaking) and dynamic weight bearing (gait) changes are not measures of neuropathic pain in mice
Jeffrey S Mogil, Allyson C Graham, Jennifer Ritchie, Sara F Hughes, Jean-Sebastien Austin, Ara Schorscher-Petcu, Dale J Langford, Gary J Bennett
Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability
Mark Estacion, Stephen G Waxman, Sulayman D Dib-Hajj
Hydrogen sulphide induces μ opioid receptor-dependent analgesia in a rodent model of visceral pain
Eleonora Distrutti, Sabrina Cipriani, Barbara Renga, Andrea Mencarelli, Marco Migliorati, Stefano Cianetti, Stefano Fiorucci
Changes in Aβ non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain
Qi Wu, James L Henry
Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord
Yoshikazu Yanagisawa, Hidemasa Furue, Tomoyuki Kawamata, Daisuke Uta, Jun Yamamoto, Shingo Furuse, Toshihiko Katafuchi, Keiji Imoto, Yukihide Iwamoto, Megumu Yoshimura
Thermal nociceptive properties of trigeminal afferent neurons in rats
Jason M Cuellar, Neil A Manering, Mikhail Klukinov, Michael I Nemenov, David C Yeomans
Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: A model of myogenic orofacial pain
Wei Guo, Hu Wang, Shiping Zou, Feng Wei, Ronald Dubner, Ke Ren
Different SNP combinations in the GCH1 gene and use of labor analgesia
Fatimah Dabo, Alfhild Grönbladh, Fred Nyberg, Inger Sundström-Poromaa, Helena Åkerud
Roles of the anterior cingulate cortex and medial thalamus in short-term and long-term aversive information processing
Sin-Chee Chai, Jen-Chuang Kung, Bai-Chuang Shyu
Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin
Mehdi Hossaini, Joost LM Jongen, Karla Biesheuvel, Dietmar Kuhl, Jan C Holstege
Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization?
James E Biggs, Van B Lu, Martin J Stebbing, Sridhar Balasubramanyan, Peter A Smith
Characterization of two Runx1-dependent nociceptor differentiation programs necessary for inflammatory versus neuropathic pain
Omar Abdel Samad, Yang Liu, Fu-Chia Yang, Ina Kramer, Silvia Arber, Qiufu Ma
Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior
Karin N Westlund, Mikhail Y Kochukov, Ying Lu, Terry A McNearney
Menthol response and adaptation in nociceptive-like and nonnociceptive-like neurons: role of protein kinases
Ignacio Sarria, Jianguo Gu
Familial hemiplegic migraine CaV2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain
Asha Nair, Manuela Simonetti, Nicol Birsa, Michel D Ferrari, Arn MJM van den Maagdenberg, Rashid Giniatullin, Andrea Nistri, Elsa Fabbretti
Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats
Wen Xu, Yuwei Wu, Yeping Bi, Lei Tan, Yehua Gan, KeWei Wang
Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain. ketamine, astrocytic inhibitor and pain
Xiao-Peng Mei, Wei Wang, Wen Wang, Chao Zhu, Lei Chen, Ting Zhang, Li-Xian Xu, Sheng-Xi Wu, Yun-Qing Li
Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia
Guang Bai, Dong Wei, Shiping Zou, Ke Ren, Ronald Dubner
Facilitation of the inhibitory transmission by gastrin-releasing peptide in the anterior cingulate cortex
XiaoYan Cao, Valentina Mercaldo, Pingyang Li, Long-Jun Wu, Min Zhuo
Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue
Virginia Ip, Johnson J Liu, Julian FB Mercer, Mark J McKeage
Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway
Sandrine M Géranton, Keri K Tochiki, Winnie WY Chiu, Sarah A Stuart, Stephen P Hunt
Nitric oxide is negatively correlated to pain during acute inflammation
May Hamza, Xiao-Min Wang, Tongtong Wu, Jaime S Brahim, Janet S Rowan, Raymond A Dionne
Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping
Meiping Chang, Sarah Smith, Andrew Thorpe, Michael J Barratt, Farzana Karim
Expression of leukotriene receptors in the rat dorsal root ganglion and the effects on pain behaviors
Masamichi Okubo, Hiroki Yamanaka, Kimiko Kobayashi, Tetsuo Fukuoka, Yi Dai, Koichi Noguchi
Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers
H Richard Koerber, Sabrina L McIlwrath, Jeffrey J Lawson, Sacha A Malin, Collene E Anderson, Michael P Jankowski, Brian M Davis
Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity
Kazunori Adachi, Kohei Shimizu, James W Hu, Ikuko Suzuki, Hiroshi Sakagami, Noriaki Koshikawa, Barry J Sessle, Masamichi Shinoda, Makiko Miyamoto, Kuniya Honda, Koichi Iwata
Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model
Mary O Adedoyin, Stefano Vicini, Joseph H Neale
Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones
Vittorio Vellani, Anna M Kinsey, Massimiliano Prandini, Sabine C Hechtfischer, Peter Reeh, Pier C Magherini, Chiara Giacomoni, Peter A McNaughton
In vivo whole-cell patch-clamp recording of sensory synaptic responses of cingulate pyramidal neurons to noxious mechanical stimuli in adult mice
Kohei Koga, Xiangyao Li, Tao Chen, Hendrik W Steenland, Giannina Descalzi, Min Zhuo
Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation
Thiago M Cunha, Jhimmy Talbot, Larissa G Pinto, Silvio M Vieira, Guilherme R Souza, Ana T Guerrero, Fabiane Sonego, Waldiceu A Verri Jr, Dario S Zamboni, Sergio H Ferreira, Fernando Q Cunha
Intraperitoneal injection of thalidomide attenuates bone cancer pain and decreases spinal tumor necrosis factor-α expression in a mouse model
Xiaoping Gu, Yaguo Zheng, Bingxu Ren, Rui Zhang, Fengmei Mei, Juan Zhang, Zhengliang Ma
Expression of inwardly rectifying potassium channels by an inducible adenoviral vector reduced the neuronal hyperexcitability and hyperalgesia produced by chronic compression of the spinal ganglion
Chao Ma, Jason Rosenzweig, Pu Zhang, David C Johns, Robert H LaMotte
Moving towards supraspinal TRPV1 receptors for chronic pain relief
Enza Palazzo, Livio Luongo, Vito de Novellis, Liberato Berrino, Francesco Rossi, Sabatino Maione
Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice
Robert JP Pope, Fiona E Holmes, Niall C Kerr, David Wynick
Aquaporin 1, a potential therapeutic target for migraine with aura
Guang-Yin Xu, Fen Wang, Xinghong Jiang, Jin Tao
Aromatase and 5-alpha reductase gene expression: modulation by pain and morphine treatment in male rats
Anna Maria Aloisi, Ilaria Ceccarelli, Paolo Fiorenzani, Melinda Maddalena, Alessandra Rossi, Valentina Tomei, Giuseppina Sorda, Barbara Danielli, Michele Rovini, Andrea Cappelli, Maurizio Anzini, Antonio Giordano
Inter-strain differences of serotonergic inhibitory pain control in inbred mice
Nina Wijnvoord, Boris Albuquerque, Annett Häussler, Thekla Myrczek, Laura Popp, Irmgard Tegeder
Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn
Paul J Wrigley, Hyo-Jin Jeong, Christopher W Vaughan
Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice
Yuki Orikawa, Hiroki Kato, Koichi Seto, Nobuyoshi Kobayashi, Koji Yoshinaga, Hiroki Hamano, Yuko Hori, Tim Meyer, Mineo Takei
Acupuncture modulates temporal neural responses in wide brain networks: evidence from fMRI study
Lijun Bai, Jie Tian, Chongguang Zhong, Ting Xue, Youbo you, Zhenyu Liu, Peng Chen, Qiyong Gong, Lin Ai, Wei Qin, Jianping Dai, Yijun Liu
Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier
Simon Beggs, Xue Jun Liu, Chun Kwan, Michael W Salter
Inflammatory nociception diminishes dopamine release and increases dopamine D2 receptor mRNA in the rat's insular cortex
Ulises Coffeen, J Manuel Ortega-Legaspi, Patricia de Gortari, Karina Simón-Arceo, Orlando Jaimes, María Isabel Amaya, Francisco Pellicer
Prevention of Paclitaxel-induced allodynia by Minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats
Cui-Cui Liu, Ning Lu, Yu Cui, Tao Yang, Zhi-Qi Zhao, Wen-Jun Xin, Xian-Guo Liu
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain
Jing Zhao, Guanglu Yuan, Cruz M Cendan, Mohammed A Nassar, Malin C Lagerström, Klas Kullander, Isabella Gavazzi, John N Wood
Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine
Jun Nagai, Hitoshi Uchida, Yosuke Matsushita, Ryo yano, Mutsumi Ueda, Masami Niwa, Junken Aoki, Jerold Chun, Hiroshi Ueda
Distinctive response of CNS glial cells in oro-facial pain associated with injury, infection and inflammation
SeungHwan Lee, Yuan Qing Zhao, Alfredo Ribeiro-da-Silva, Ji Zhang
Imaging the functional connectivity of the Periaqueductal Gray during genuine and sham electroacupuncture treatment
Carolyn E Zyloney, Karin Jensen, Ginger Polich, Rita E Loiotile, Alexandra Cheetham, Peter S LaViolette, Peichi Tu, Ted J Kaptchuk, Randy L Gollub, Jian Kong
"First pain" in humans: convergent and specific forebrain responses
Dagfinn A Matre, Luis Hernandez-Garcia, Tuan D Tran, Kenneth L Casey
Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
Uma Anand, William R Otto, Praveen Anand
Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain
Naoki Kusunose, Satoru Koyanagi, Kengo Hamamura, Naoya Matsunaga, Miyako Yoshida, Takahiro Uchida, Makoto Tsuda, Kazuhide Inoue, Shigehiro Ohdo
Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
Anna-Karin Persson, Joel A Black, Andreas Gasser, Xiaoyang Cheng, Tanya Z Fischer, Stephen G Waxman
Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCϵ pathway in dorsal root ganglion neurons
Hai-Li Pan, Yu-Qiu Zhang, Zhi-Qi Zhao
PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects
Patrycja Kleczkowska, Piotr Kosson, Steven Ballet, Isabelle Van den Eynde, Yuko Tsuda, Dirk Tourwé, Andrzej W Lipkowski
Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain
Joseph R Ghilardi, Katie T Freeman, Juan M Jimenez-Andrade, William G Mantyh, Aaron P Bloom, Michael A Kuskowski, Patrick W Mantyh
ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain
Wei-Guang Li, Ye Yu, Zhu-Dan Zhang, Hui Cao, Tian-Le Xu
Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus
Giovanni Villa, Stefania Ceruti, Matteo Zanardelli, Giulia Magni, Luc Jasmin, Peter T Ohara, Maria P Abbracchio
Blocking spinal CCR2 with AZ889 reversed hyperalgesia in a model of neuropathic pain
Alexandre Serrano, Michel Paré, Fraser McIntosh, Steven JR Elmes, Giovanni Martino, Claudia Jomphe, Etienne Lessard, Paola MC Lembo, François Vaillancourt, Martin N Perkins, Chang Qing Cao
Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis
Ryan J Cady, Jeffery J Hirst, Paul L Durham
Potentiation of excitatory transmission in substantia gelatinosa neurons of rat spinal cord by inhibition of estrogen receptor alpha
Yan-Qing Zhong, Kai-Cheng Li, Xu Zhang
Pain-related increase of excitatory transmission and decrease of inhibitory transmission in the central nucleus of the amygdala are mediated by mGluR1
Wenjie Ren, Volker Neugebauer
Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates
Kendall Mitchell, Brian D Bates, Jason M Keller, Matthew Lopez, Lindsey Scholl, Julia Navarro, Nicholas Madian, Gal Haspel, Michael I Nemenov, Michael J Iadarola
DREAM regulates BDNF-dependent spinal sensitization
Ivan Rivera-Arconada, Tomaso Benedet, Carolina Roza, Begoña Torres, Jorge Barrio, Agnieszka Krzyzanowska, Carlos Avendaño, Britt Mellström, José A Lopez-Garcia, José R Naranjo
Abnormal nociception and opiate sensitivity of STOP null mice exhibiting elevated levels of the endogenous alkaloid morphine
Alexandre Charlet, Arnaud H Muller, Alexis Laux, Véronique Kemmel, Annie Schweitzer, Jean-Christophe Deloulme, Denise Stuber, François Delalande, Enrica Bianchi, Alain Van Dorsselaer, Dominique Aunis, Annie Andrieux, Pierrick Poisbeau, Yannick Goumon
Analgesic effect of highly reversible ω-conotoxin FVIA on N-type Ca2+ channels
Seungkyu Lee, Yoonji Kim, Seung Keun Back, Hee Woo Choi, Ju Yeon Lee, Hyun Ho Jung, Jae Ha Ryu, Hong Won Suh, Heung Sik Na, Hyun Jeong Kim, Hyewhon Rhim, Jae Il Kim
Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitization
Christine Andres, Sonja Meyer, Olayinka A Dina, Jon D Levine, Tim Hucho