BMC Cancer

A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway

• Open Access
• Research article

Yue-Li Sun, Wen-Qi Jiang, Qiu-Yun Luo, Da-Jun Yang, Yu-Chen Cai, Hui-Qiang Huang, Jian Sun

Comorbidity prevalence among cancer patients: a population-based cohort study of four cancers

• Open Access
• Research article

Helen Fowler, Aurelien Belot, Libby Ellis, Camille Maringe, Miguel Angel Luque-Fernandez, Edmund Njeru Njagi, Neal Navani, Diana Sarfati, Bernard Rachet

Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells

• Open Access
• Research article

Marc El Beaino, Jiayong Liu, Amanda R. Wasylishen, Rasoul Pourebrahim, Agata Migut, Bryan J. Bessellieu, Ke Huang, Patrick P. Lin

Phytochemicals inhibit migration of triple negative breast cancer cells by targeting kinase signaling

• Open Access
• Research article

Pradip Shahi Thakuri, Megha Gupta, Sunil Singh, Ramila Joshi, Eric Glasgow, Alexander Lekan, Seema Agarwal, Gary D. Luker, Hossein Tavana

TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

• Open Access
• Research article

Keiichi Akizuki, Masaaki Sekine, Yasunori Kogure, Takuro Kameda, Kotaro Shide, Junji Koya, Ayako Kamiunten, Yoko Kubuki, Yuki Tahira, Tomonori Hidaka, Takumi Kiwaki, Hiroyuki Tanaka, Yuichiro Sato, Hiroaki Kataoka, Keisuke Kataoka, Kazuya Shimoda

Diagnostic value of plasma HSP90α levels for detection of hepatocellular carcinoma

• Open Access
• Research article

Wene Wei, Mengshu Liu, Shufang Ning, Jing Wei, Jianhong Zhong, Jilin Li, Zhengmin Cai, Litu Zhang

Convection-enhanced delivery of temozolomide and whole cell tumor immunizations in GL261 and KR158 experimental mouse gliomas

• Open Access
• Research article

Julio Enríquez Pérez, Jan Kopecky, Edward Visse, Anna Darabi, Peter Siesjö

Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer – study protocol of a prospective, single arm, multicenter phase II trial (RACE IT)

• Open Access
• Study protocol

Sebastian C. Schmid, Florestan J. Koll, Claus Rödel, Philipp Maisch, Andreas Sauter, Franziska Beckert, Anna Seitz, Hubert Kübler, Michael Flentje, Felix Chun, Stephanie E. Combs, Kilian Schiller, Jürgen E. Gschwend, Margitta Retz

A cross sectional study to determine the prevalence of cough and its impact in patients with lung cancer: a patient unmet need

• Open Access
• Research article

Amélie Harle, Alex Molassiotis, Oliver Buffin, Jack Burnham, Jaclyn Smith, Janelle Yorke, Fiona H. Blackhall

Nomogram for predicting the survival of gastric adenocarcinoma patients who receive surgery and chemotherapy

• Open Access
• Research article

Chao-Yang Wang, Jin Yang, Hao Zi, Zhong-Li Zheng, Bing-Hui Li, Yang Wang, Zheng Ge, Guang-Xu Jian, Jun Lyu, Xiao-Dong Li, Xue-Qun Ren

Complete blood count-based inflammatory score (CBCS) is a novel prognostic marker for gastric cancer patients after curative resection

• Open Access
• Research article

Jian-Xian Lin, Jun-Peng Lin, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin, Ruhong Tu, Chao-Hui Zheng, Chang-Ming Huang, Ping Li

Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma

• Open Access
• Research article

Simon Schallenberg, Julian Bork, Ahlem Essakly, Hakan Alakus, Reinhard Buettner, Axel M. Hillmer, Christiane Bruns, Wolfgang Schroeder, Thomas Zander, Heike Loeser, Florian Gebauer, Alexander Quaas

Fast growing angiosarcoma of the right atrium after radiofrequency catheter ablation: a missed diagnosis or misdiagnosis case report

• Open Access
• Case report

Yi Yu, Qunshan Wang, Jian Sun, Jing Zhao, Suyun Chen, Yigang Li

Crizotinib-induced osteitis mimicking bone metastasis in a stage IV ALK-rearranged NSCLC patient: a case report

• Open Access
• Case report

F. Guisier, N. Piton, M. Bellefleur, N. Delberghe, G. Avenel, E. Angot, O. Vittecoq, M. Ould-Slimane, H. Morisse-Pradier, M. Salaun, L. Thiberville

Simultaneous occurrence of invasive pulmonary aspergillosis and diffuse large B-cell lymphoma: case report and literature review

• Open Access
• Case report

Lianyou Shao, Longxiang Jiang, Siyao Wu, Lihua Yu, Liangxing Wang, Xiaoying Huang

Comprehensive assessments and related interventions to enhance the long-term outcomes of child, adolescent and young adult cancer survivors – presentation of the CARE for CAYA-Program study protocol and associated literature review

• Open Access
• Study protocol

J. Salchow, J. Mann, B. Koch, J. von Grundherr, W. Jensen, S. Elmers, L. A. Straub, E. Vettorazzi, G. Escherich, S. Rutkowski, S. Dwinger, C. Bergelt, M. Sokalska-Duhme, S. Bielack, G. Calaminus, K. Baust, C. F. Classen, C. Rössig, J. Faber, H. Faller, I. Hilgendorf, J. Gebauer, T. Langer, M. Metzler, S. Schuster, C. Niemeyer, A. Puzik, D. Reinhardt, U. Dirksen, A. Sander, M. Köhler, J. K. Habermann, C. Bokemeyer, A. Stein

Increased levels of XPA might be the basis of cisplatin resistance in germ cell tumours

• Open Access
• Research article

Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec

AJCC 8th edition prognostic staging provides no better discriminatory ability in prognosis than anatomical staging in triple negative breast cancer

• Open Access
• Research article

Jiehua He, Julia Y. Tsang, Xiaodan Xu, Jibin Li, Mei Li, Xue Chao, Yuanyuan Xu, Rongzhen Luo, Gary M. Tse, Peng Sun

Effect of adjuvant chemotherapy on survival benefit in stage III colon cancer patients stratified by age: a Japanese real-world cohort study

• Open Access
• Research article

Hidetaka Kawamura, Toshitaka Morishima, Akira Sato, Michitaka Honda, Isao Miyashiro

Long-term outcomes of surgical resection for T1b gallbladder cancer: an institutional evaluation

• Open Access
• Research article

Kizuki Yuza, Jun Sakata, Pankaj Prasoon, Yuki Hirose, Taku Ohashi, Koji Toge, Kohei Miura, Masayuki Nagahashi, Takashi Kobayashi, Toshifumi Wakai

Adaptive radiotherapy in locally advanced esophageal cancer with atelectasis: a case report

• Open Access
• Case report

Katsuyuki Sakanaka, Kota Fujii, Takashi Mizowaki

Major differences in follow-up practice of patients with colorectal cancer; results of a national survey in the Netherlands

• Open Access
• Research article

S. M. Qaderi, N. A. T. Wijffels, A. J. A. Bremers, J. H. W. de Wilt

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

• Open Access
• Research article

Talita Diniz Melo-Hanchuk, Mariana Bonjiorno Martins, Lucas Leite Cunha, Fernando Augusto Soares, Laura Sterian Ward, José Vassallo, Jörg Kobarg

Combining therapy with recombinant human endostatin and cytotoxic agents for recurrent disseminated glioblastoma: a retrospective study

• Open Access
• Research article

Jing-jing Ge, Cheng Li, Shao-pei Qi, Feng-jun Xue, Zhi-meng Gao, Chun-jiang Yu, Jun-ping Zhang

Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells

• Open Access
• Research article

Kazushige Yoshida, Masanori Okamoto, Jun Sasaki, Chika Kuroda, Haruka Ishida, Katsuya Ueda, Hirokazu Ideta, Takayuki Kamanaka, Atsushi Sobajima, Takashi Takizawa, Manabu Tanaka, Kaoru Aoki, Takeshi Uemura, Hiroyuki Kato, Hisao Haniu, Naoto Saito

An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer

• Open Access
• Research Article

Qing Wang, Zhijun Wang, Yan Wu, David J. Klinke II

P53, Somatostatin receptor 2a and Chromogranin A immunostaining as prognostic markers in high grade gastroenteropancreatic neuroendocrine neoplasms

• Open Access
• Research article

Kirstine Nielsen, Tina Binderup, Seppo W. Langer, Andreas Kjaer, Pauline Knigge, Veronica Grøndahl, Linea Melchior, Birgitte Federspiel, Ulrich Knigge

Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

• Open Access
• Research article

Ye Yang, Ping Yin Liu, Wei Bao, Song Jun Chen, Fang Su Wu, Ping Ya Zhu

A systematic review reporting quality of radiomics research in neuro-oncology: toward clinical utility and quality improvement using high-dimensional imaging features

• Open Access
• Research article

Ji Eun Park, Ho Sung Kim, Donghyun Kim, Seo Young Park, Jung Youn Kim, Se Jin Cho, Jeong Hoon Kim

Childhood cancer incidence and survival trends in Estonia (1970–2016): a nationwide population-based study

• Open Access
• Research article

Keiu Paapsi, Aleksei Baburin, Sirje Mikkel, Margit Mägi, Kadri Saks, Kaire Innos

Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma

• Open Access
• Research article

Xia Liao, Ge Song, Zihan Xu, Yang Bu, Fan Chang, Fengan Jia, Xuelian Xiao, Xuejiao Ren, Mei Zhang, Qingan Jia

Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling

• Open Access
• Research article

Ji-Gang Zhang, He-Ming Zhou, Xue Zhang, Wan Mu, Juan-Ni Hu, Gao-Lin Liu, Qin Li

Elevated matrix metalloproteinase 7 expression promotes the proliferation, motility and metastasis of tongue squamous cell carcinoma

• Open Access
• Research article

Shuo Yuan, Li-song Lin, Rui-Huan Gan, Li Huang, Xiao-ting Wu, Yong Zhao, Bo-hua Su, Dali Zheng, You-Guang Lu

Young-onset gastric cancer and Epstein–Barr Virus (EBV) – a major player in the pathogenesis?

• Open Access
• Research article

Assaf Moore, Elad Hikri, Tal Goshen-Lago, Tamar Barkan, Sara Morgenstern, Elena Brook, Annett Maderer, Wilfried Roth, Noa Gordon, Hanoch Kashtan, Baruch Brenner, Markus Moehler, Irit Ben Aharon

Prognostic factors of patients with Gliomas – an analysis on 335 patients with Glioblastoma and other forms of Gliomas

• Open Access
• Research article

Jianfeng Liang, Xiaomin Lv, Changyu Lu, Xun Ye, Xiaolin Chen, Jia Fu, Chenghua Luo, Yuanli Zhao

Does chemoradiotherapy benefit elderly patients with esophageal squamous cell cancer? A propensity-score matched analysis on multicenter data (3JECROG R-03A)

• Open Access
• Research article

Mingqiu Chen, Xiaohong Liu, Chun Han, Xin Wang, Yidian Zhao, Qingsong Pang, Xinchen Sun, Gaofeng Li, Kaixian Zhang, Ling Li, Xueying Qiao, Yu Lin, Junqiang Chen, Zefen Xiao

Establishment and validation of a nomogram with intratumoral heterogeneity derived from 18F-FDG PET/CT for predicting individual conditional risk of 5-year recurrence before initial treatment of nasopharyngeal carcinoma

• Open Access
• Research article

Bingxin Gu, Jianping Zhang, Guang Ma, Shaoli Song, Liqun Shi, Yingjian Zhang, Zhongyi Yang

Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report

• Open Access
• Case report

Claire M. Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I. Jodrell

Bacteriocin production by mucosal bacteria in current and previous colorectal neoplasia

• Open Access
• Research article

Darina Kohoutova, Miroslava Forstlova, Paula Moravkova, Jiri Cyrany, Juraj Bosak, David Smajs, Stanislav Rejchrt, Jan Bures

Comprehensive profiling of circular RNA expressions reveals potential diagnostic and prognostic biomarkers in multiple myeloma

• Open Access
• Research article

Fan Zhou, Dongjiao Wang, Wei Wei, Haimin Chen, Haotian Shi, Nian Zhou, Lixia Wu, Rong Peng

GC-PROM: validation of a patient-reported outcomes measure for Chinese patients with gastric cancer

• Open Access
• Research article

Xiaojuan Hu, Fen Zhao, Hongmei Yu, Yanhong Luo, Jinchun Liu, Yanbo Zhang

Correction to: Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects

• Open Access
• Correction

Hongwei Tian, Gang Shi, Guoyou Yang, Junfeng Zhang, Yiming Li, Tao Du, Jianzhou Wang, Fen Xu, Lin Cheng, Xiaomei Zhang, Lei Dai, Xiaolei Chen, Shuang Zhang, Yang Yang, Dechao Yu, Yuquan Wei, Hongxin Deng

Correction to: TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-catenin

• Open Access
• Correction

Yanan Jiang, Jing Zhang, Jimin Zhao, Zhenzhen Li, Hanyong Chen, Yan Qiao, Xinhuan Chen, Kangdong Liu, Ziming Dong

3D visualization ablation planning system assisted microwave ablation for hepatocellular carcinoma (Diameter >3): a precise clinical application

• Open Access
• Research article

Chao An, Xin Li, Min Zhang, Jian Yang, Zhigang Cheng, Xiaoling Yu, Zhiyu Han, Fangyi Liu, Linan Dong, Jie Yu, Ping Liang

Identification of dissociation factors in pancreatic Cancer using a mass spectrometry-based proteomic approach

• Open Access
• Research article

Peng Liu, Lingming Kong, Keke Liang, Yunhao Wu, Haoyi Jin, Bing Song, Xiaodong Tan

IL-1-conferred gene expression pattern in ERα+ BCa and AR+ PCa cells is intrinsic to ERα− BCa and AR− PCa cells and promotes cell survival

• Open Access
• Research article

Afshan F. Nawas, Mohammed Kanchwala, Shayna E. Thomas-Jardin, Haley Dahl, Kelly Daescu, Monica Bautista, Vanessa Anunobi, Ally Wong, Rachel Meade, Ragini Mistry, Nisha Ghatwai, Felix Bayerl, Chao Xing, Nikki A. Delk

Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report

• Open Access
• Case report

Melissa Umphlett, Stephanie Shea, Jessica Tome-Garcia, Yizhou Zhang, Adilia Hormigo, Mary Fowkes, Nadejda M. Tsankova, Raymund L. Yong

Space-time clustering of childhood leukemia in Colombia: a nationwide study

• Open Access
• Research article

Laura Andrea Rodriguez-Villamizar, Marcela Pilar Rojas Díaz, Lizbeth Alexandra Acuña Merchán, Feisar Enrique Moreno-Corzo, Paula Ramírez-Barbosa

Pathological complete response due to a prolonged time interval between preoperative chemoradiation and surgery in locally advanced rectal cancer: analysis from the German StuDoQ|Rectalcarcinoma registry

• Open Access
• Research article

Sven Lichthardt, Johanna Wagner, Stefan Löb, Niels Matthes, Caroline Kastner, Friedrich Anger, Christoph-Thomas Germer, Armin Wiegering

Improving management of comorbidity in patients with colorectal cancer using comprehensive medical assessment: a pilot study

• Open Access
• Research article

Virginia Signal, Christopher Jackson, Louise Signal, Claire Hardie, Kirsten Holst, Marie McLaughlin, Courtney Steele, Diana Sarfati

The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study

• Open Access
• Research article

Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt

Intrafractional vaginal dilation in anal cancer patients undergoing pelvic radiotherapy (DILANA) – a prospective, randomized, 2-armed phase-II-trial

• Open Access
• Study protocol

Nathalie Arians, Matthias Häfner, Johannes Krisam, Kristin Lang, Antje Wark, Stefan A. Koerber, Adriane Hommertgen, Jürgen Debus

Systemic treatment of hormone receptor positive, human epidermal growth factor 2 negative metastatic breast cancer: retrospective analysis from Leeds Cancer Centre

• Open Access
• Research article

Chris Twelves, Sue Cheeseman, Will Sopwith, Matthew Thompson, Majid Riaz, Necibe Ahat-Donker, Melissa Myland, Adam Lee, Raymond Przybysz, Stuart Turner, Geoff Hall, Tim Perren

Hepatocellular carcinoma with hilar bile duct tumor thrombus versus hilar Cholangiocarcinoma on enhanced computed tomography: a diagnostic challenge

• Open Access
• Research article

Xiaoqi Zhou, Jifei Wang, Mimi Tang, Mengqi Huang, Ling Xu, Zhenpeng Peng, Zi-Ping Li, Shi-Ting Feng

Correction to: Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signaling

• Open Access
• Correction

Gisela Nilsson, Marie Kannius-Janson

Systematical identifications of prognostic meaningful lung adenocarcinoma subtypes and the underlying mutational and expressional characters

• Open Access
• Research article

Zhenyang Lv, Ting Lei

Efficacy and safety of self-expanding metallic stent placement followed by neoadjuvant chemotherapy and scheduled surgery for treatment of obstructing left-sided colonic cancer

• Open Access
• Research article

Jia Gang Han, Zhen Jun Wang, Wei Gen Zeng, Yan Bin Wang, Guang Hui Wei, Zhi Wei Zhai, Bao Cheng Zhao, Bing Qiang Yi

Immune classification for the PD-L1 expression and tumour-infiltrating lymphocytes in colorectal adenocarcinoma

• Open Access
• Research article

Byeong-Joo Noh, Jae Young Kwak, Dae-Woon Eom

Prognostic value and clinicopathological characteristics of PD-L1 overexpression in non-Hodgkin lymphoma: a meta-analysis

• Open Access
• Research article

Qiang Zeng, Zhigang Liu, Ting Liu

CT features and quantitative analysis of subsolid nodule lung adenocarcinoma for pathological classification prediction

• Open Access
• Research article

Xiaohu Li, Wei Zhang, Yongqiang Yu, Guihong Zhang, Lifen Zhou, Zongshan Wu, Bin Liu

The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience

• Open Access
• Research article

Zhuo Liu, Shiying Tang, Xiaojun Tian, Hongxian Zhang, Guoliang Wang, Shudong Zhang, Lulin Ma

NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma

• Open Access
• Research article

Chitrangda Srivastava, Khushboo Irshad, Yakhlesh Gupta, Chitra Sarkar, Ashish Suri, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol

Women’s knowledge of and attitudes toward cervical cancer and cervical cancer screening in Zanzibar, Tanzania: a cross-sectional study

• Open Access
• Research article

Qiao Weng, Jie Jiang, Fatma Mrisho Haji, Lamlet Hassan Nondo, Huaijun Zhou

Detection of early adenocarcinoma of the esophagogastric junction by spraying an enzyme-activatable fluorescent probe targeting Dipeptidyl peptidase-IV

• Open Access
• Research article

Keiko Yamamoto, Shunsuke Ohnishi, Takeshi Mizushima, Junichi Kodaira, Masayoshi Ono, Yutaka Hatanaka, Kanako C. Hatanaka, Yugo Kuriki, Mako Kamiya, Nobuyuki Ehira, Keisuke Shinada, Hiroaki Takahashi, Yuichi Shimizu, Yasuteru Urano, Naoya Sakamoto

Key genes with prognostic values in suppression of osteosarcoma metastasis using comprehensive analysis

• Open Access
• Research article

Mi Li, Xin Jin, Hao Li, Gang Wu, Shanshan Wang, Caihong Yang, Sisi Deng

The neurocognitive function change criteria after whole-brain radiation therapy for brain metastasis, in reference to health-related quality of life changes: a prospective observation study

• Open Access
• Research article

Toshimichi Nakano, Hidefumi Aoyama, Hirotake Saito, Satoshi Tanabe, Kensuke Tanaka, Katsuya Maruyama, Tomoya Oshikane, Atsushi Ohta, Eisuke Abe, Motoki Kaidu

Ovarian hyperstimulation closely associated with resumption of follicular growth after chemotherapy during tamoxifen treatment in premenopausal women with breast cancer: a multicenter retrospective cohort study

• Open Access
• Research article

Rena Yamazaki, Masafumi Inokuchi, Satoko Ishikawa, Takuya Ayabe, Hiromitsu Jinno, Takashi Iizuka, Masanori Ono, Subaru Myojo, Soko Uchida, Toshiya Matsuzaki, Akira Tangoku, Masato Kita, Tomoharu Sugie, Hiroshi Fujiwara

Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience

• Open Access
• Research article

Jana Käthe Striefler, Franziska Brandes, Alexander Baur, Berit Maria Pfitzner, David Kaul, Daniel Rau, Anne Dörr, Maren Schmiester, Georgios Koulaxouzidis, Lars Bullinger, Sven Märdian, Anne Flörcken

Superiority of NBI endoscopy to PET/CT scan in detecting esophageal cancer among head and neck cancer patients: a retrospective cohort analysis

• Open Access
• Research article

Hsuan-An Su, Shun-Wen Hsiao, Yu-Chun Hsu, Lien-Yen Wang, Hsu-Heng Yen

Childhood maltreatment as a risk factor for cancer: findings from a population-based survey of Canadian adults

• Open Access
• Research article

Wendy E. Hovdestad, Margot Shields, Amanda Shaw, Lil Tonmyr

Real-world use of chemotherapy for Kaposi’s sarcoma in a large community-based HIV primary care system in Kenya

• Open Access
• Research article

Esther E. Freeman, Naftali Busakhala, Susan Regan, Fredrick Chite Asirwa, Megan Wenger, Divya Seth, Khatiya Chelidze Moon, Aggrey Semeere, Toby Maurer, Kara Wools-Kaloustian, Ingrid Bassett, Jeffrey Martin

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

• Open Access
• Research article

Vahinipriya Manoharan, Eric Hamilton Karunanayake, Kamani Hemamala Tennekoon, Sumadee De Silva, Ahamed Ilyas Ahamed Imthikab, Kanishka De Silva, Preethika Angunawela, Sameera Vishwakula, John Lunec

Comparison of fully-covered vs partially covered self-expanding metallic stents for palliative treatment of inoperable esophageal malignancy: a systematic review and meta-analysis

• Open Access
• Research article

Chunmei Wang, Hua Wei, Yuxia Li

Treatment intensification with hepatic arterial infusion chemotherapy in patients with liver-only colorectal metastases still unresectable after systemic induction chemotherapy – a randomized phase II study -- SULTAN UCGI 30/PRODIGE 53 (NCT03164655)- study protocol

• Open Access
• Study protocol

Alice Boilève, Aline Maillard, Mathilde Wagner, Clarisse Dromain, Christophe Laurent, Eric Dupont Bierre, Samuel Le Sourd, Franck Audemar, Ayhan Ulusakarya, Veronique Guerin-Meyer, Denis Smisth, Veronica Pezzella, Thierry De Baere, Diane Goere, Maximiliano Gelli, Julien Taieb, Valérie Boige

Moderately hypofractionated carbon ion radiotherapy for prostate cancer; a prospective observational study “GUNMA0702”

• Open Access
• Research article

Hidemasa Kawamura, Nobuteru Kubo, Hiro Sato, Tatsuji Mizukami, Hiroyuki Katoh, Hitoshi Ishikawa, Tatsuya Ohno, Hiroshi Matsui, Kazuto Ito, Kazuhiro Suzuki, Takashi Nakano, Kazuhiro Suzuki, Kazuto Ito, Nobuaki Shimizu, Yutaka Takezawa, Junko Hirato, Hitoshi Ishikawa, Hiroshi Matsui, Hiroyuki Katoh, Tatsuya Ohno, Hidemasa Kawamura

Icotinib is as efficacious as gefitinib for brain metastasis of EGFR mutated non-small-cell lung cancer

• Open Access
• Research article

Kejun Liu, Guanming Jiang, Ailing Zhang, Zhuanghua Li, Jun Jia

Prognostic and clinicopathological significance of SNHG6 in human cancers: a meta-analysis

• Open Access
• Research article

Si Zhao, Hanlong Zhu, Ruonan Jiao, Xueru Wu, Guozhong Ji, Xiuhua Zhang

Oncologic outcomes after immediate breast reconstruction following mastectomy: comparison of implant and flap using propensity score matching

• Open Access
• Research article

Jeong Hyun Ha, Ki Yong Hong, Han-Byoel Lee, Hyeong-Gon Moon, Wonshik Han, Dong-Young Noh, Joonho Lim, Sehoon Yoon, Hak Chang, Ung Sik Jin

Incidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study

• Open Access
• Research article

Samantha Ya Lyn Ang, Lester Lee, Angela An Qi See, Ting Yao Ang, Beng Ti Ang, Nicolas Kon Kam King

A web application for the design of multi-arm clinical trials

• Open Access
• Software

Michael J. Grayling, James MS. Wason

MammaPrint guides treatment decisions in breast Cancer: results of the IMPACt trial

• Open Access
• Research article

Hatem Soliman, Varsha Shah, Gordan Srkalovic, Reshma Mahtani, Ellis Levine, Blanche Mavromatis, Jayanthi Srinivasiah, Mohamad Kassar, Robert Gabordi, Rubina Qamar, Sarah Untch, Heather M. Kling, Tina Treece, William Audeh

PDAC-ANN: an artificial neural network to predict pancreatic ductal adenocarcinoma based on gene expression

• Open Access
• Software

Palloma Porto Almeida, Cristina Padre Cardoso, Leandro Martins de Freitas

Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations

• Open Access
• Research article

Roberto Ruiz-Cordero, Junsheng Ma, Abha Khanna, Genevieve Lyons, Waree Rinsurongkawong, Roland Bassett, Ming Guo, Mark J. Routbort, Jianjun Zhang, Ferdinandos Skoulidis, John Heymach, Emily B. Roarty, Zhenya Tang, L. Jeffrey Medeiros, Keyur P. Patel, Rajyalakshmi Luthra, Sinchita Roy-Chowdhuri

Genomic subtyping of liver cancers with prognostic application

• Open Access
• Research article

Zhenggang Wu, Xi Long, Shui Ying Tsang, Taobo Hu, Jian-Feng Yang, Wai Kin Mat, Hongyang Wang, Hong Xue

Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection

• Open Access
• Research article

Manny D. Bacolod, Jianmin Huang, Sarah F. Giardina, Philip B. Feinberg, Aashiq H. Mirza, Alexander Swistel, Steven A. Soper, Francis Barany

Current status of the clinical use of PD-1/PD-L1 inhibitors: a questionnaire survey of oncologists in China

• Open Access
• Research article

Bicheng Zhang, Yuxiao Song, Yang Fu, Bo Zhu, Baocheng Wang, Jun Wang

Correction to: The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study

• Open Access
• Correction

Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt, K. Staehelin, C. Bouchardy, M. Mousavi, J. L. Bulliard, M. Maspoli, M. Mousavi, A. Bordoni, I. Konzelmann, J. L. Bulliard, R. BlancMoya, S. Rohrmann

The influence of radiotherapy techniques on the plan quality and on the risk of secondary tumors in patients with pituitary adenoma

• Open Access
• Research article

Marius Treutwein, Felix Steger, Rainer Loeschel, Oliver Koelbl, Barbara Dobler

Comparing three induction chemotherapy regimens for patients with locoregionally advanced nasopharyngeal carcinoma based on TNM stage and plasma Epstein–Barr virus DNA level

• Open Access
• Research article

Sai-Lan Liu, Xue-Song Sun, Hao-Jun Xie, Qiu-Yan Chen, Huan-Xin Lin, Hu Liang, Yu-Jing Liang, Xiao-Yun Li, Jin-Jie Yan, Chao Lin, Zhen-Chong Yang, Shan-Shan Guo, Li-Ting Liu, Qing-Nan Tang, Yu-Yun Du, Lin-Quan Tang, Ling Guo, Hai-Qiang Mai

Radiotherapy of prostate cancer: impact of treatment characteristics on the incidence of second tumors

• Open Access
• Research article

Milly BUWENGE, Erica SCIROCCO, Francesco DEODATO, Gabriella MACCHIA, Maria NTRETA, Silvia BISELLO, Giambattista SIEPE, Savino CILLA, Anna Rita ALITTO, Vincenzo VALENTINI, Lidia STRIGARI, Alessio G. MORGANTI, Silvia CAMMELLI

Review of metastatic colorectal cancer treatment pathways and early clinical experience of trifluridine/tipiracil in the UK named patient programme

• Open Access
• Research article

Timothy Iveson, Angela M. Carter, Kai-Keen Shiu, Clare Spooner, Daniel Stevens, Saifee Mullamitha

IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer?

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Feier Chen, Meng Qu, Feng Zhang, Zhenyu Tan, Qinghua Xia, Brett D. Hambly, Shisan Bao, Kun Tao

Prediction of patients with a tumor proportion score > 50% who do not respond to first-line monotherapy with pembrolizumab

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Mitsunori Morita, Motohiro Tamiya, Daichi Fujimoto, Akihiro Tamiya, Hidekazu Suzuki, Katsuya Hirano, Yasushi Fukuda, Toshihide Yokoyama, Ryota Kominami, Masaki Kanazu, Junji Uchida, Satoshi Hara, Shuji Yamashita, Hiromi Tomioka

Development of a risk-stratification scoring system for predicting lymphovascular invasion in breast cancer

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Ma-yi-di-li Ni-jia-ti, Di-li-a-re-mu Ai-hai-ti, Ai-si-ka-er-jiang Huo-jia, Pa-li-dan-mu Wu-mai-er, A-bu-du-ke-you-mu-jiang A-bu-li-zi, Yu Shi, Nu-er-a-mi-na Rou-zi, Wen-jing Su, Guo-zhao Dai, Mai-he-mi-ti-jiang Da-mo-la

The prognostic value of neuromedin U in patients with hepatocellular carcinoma

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Qiao Li, Lingyu Han, Shengnan Ruan, Shunli Shen, Qinghua Cao, Xiuqin Cai, Yuan Yan, Baogang Peng, Yunpeng Hua

A decrease in brown adipose tissue activity is associated with weight gain during chemotherapy in early breast cancer patients

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Angeline Ginzac, Bertrand Barres, Marion Chanchou, Emilie Gadéa, Ioana Molnar, Charles Merlin, Bruno Coudert, Emilie Thivat, Xavier Durando

Development and validation of a preoperative nomogram for predicting survival of patients with locally advanced prostate cancer after radical prostatectomy

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Xianghong Zhou, Qingyang Ning, Kun Jin, Tao Zhang, Xuelei Ma

Satisfaction with high-resolution anoscopy for anal cancer screening among men who have sex with men: a cross-sectional survey in Abuja, Nigeria

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Rebecca G. Nowak, Chinedu H. Nnaji, Wuese Dauda, Andrew Mitchell, Oluwole Olaomi, Paul Jibrin, Trevor A. Crowell, Stefan D. Baral, Nicaise Ndembi, Manhattan E. Charurat, Joel M. Palefsky, Søren M. Bentzen, Kevin J. Cullen, Manhattan Charurat, Julie Ake, Sylvia Adebajo, Stefan Baral, Erik Billings, Trevor Crowell, George Eluwa, Charlotte Gaydos, Sosthenes Ketende, Afoke Kokogho, Hongjie Liu, Jennifer Malia, Olumide Makanjuola, Nelson Michael, Nicaise Ndembi, Jean Njab, Rebecca Nowak, Oluwasolape Olawore, Zahra Parker, Sheila Peel, Habib Ramadhani, Merlin Robb, Cristina Rodriguez-Hart, Eric Sanders-Buell, Sodsai Tovanabutra, Erik Volz

Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors

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César Serrano, Ana Vivancos, Antonio López-Pousa, Judit Matito, Francesco M. Mancuso, Claudia Valverde, Sergi Quiroga, Stefania Landolfi, Sandra Castro, Cristina Dopazo, Ana Sebio, Anna C. Virgili, María M. Menso, Javier Martín-Broto, Miriam Sansó, Alfonso García-Valverde, Jordi Rosell, Jonathan A. Fletcher, Suzanne George, Joan Carles, Joaquín Arribas

Predicting the response to neoadjuvant chemotherapy for breast cancer: wavelet transforming radiomics in MRI

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Jiali Zhou, Jinghui Lu, Chen Gao, Jingjing Zeng, Changyu Zhou, Xiaobo Lai, Wenli Cai, Maosheng Xu

Coffee drinking and cancer risk: an umbrella review of meta-analyses of observational studies

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Long-Gang Zhao, Zhuo-Ying Li, Guo-Shan Feng, Xiao-Wei Ji, Yu-Ting Tan, Hong-Lan Li, Marc J. Gunter, Yong-Bing Xiang

Increased plasma concentration of cell-free DNA precedes disease recurrence in children with high-risk neuroblastoma

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Yan Su, Lijun Wang, Chiyi Jiang, Zhixia Yue, Hongjun Fan, Huimin Hong, Chao Duan, Mei Jin, Dawei Zhang, Lihua Qiu, Xianfeng Cheng, Zhong Xu, Xiaoli Ma

Differential significance of molecular subtypes which were classified into EGFR exon 19 deletion on the first line afatinib monotherapy

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Nahomi Tokudome, Yasuhiro Koh, Hiroaki Akamatsu, Daichi Fujimoto, Isamu Okamoto, Kazuhiko Nakagawa, Toyoaki Hida, Fumio Imamura, Satoshi Morita, Nobuyuki Yamamoto

Tumour content ratio matters for detecting epidermal growth factor receptor mutation by cobas test in small biopsies; a retrospective study

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Mariko Kogo, Daichi Fujimoto, Kazutaka Hosoya, Kazuma Nagata, Atsushi Nakagawa, Ryo Tachikawa, Daisuke Yamashita, Yuka Kitamura, Yukihiro Imai, Keisuke Tomii

Bidirectional treatment of peritoneal metastasis with Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) and systemic chemotherapy: a systematic review

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Magnus Ploug, Martin Graversen, Per Pfeiffer, Michael Bau Mortensen

The combination of CTCs and CEA can help guide the management of patients with SPNs suspected of being lung cancer

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Jian Zheng, Xiong Ye, Yanan Liu, Yuxia Zhao, Mudan He, Hui Xiao

Linc01234 promotes cell proliferation and metastasis in oral squamous cell carcinoma via miR-433/PAK4 axis

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Deyu Liu, Xinchun Jian, Pu Xu, Rong Zhu, Yuan Wang

Young-onset colorectal cancer in the North East of Scotland: survival, clinico-pathological features and genetics

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Sarah Perrott, Kirsten Laurie, Kirsten Laws, Annie Johnes, Zosia Miedzybrodzka, Leslie Samuel

Management of patients with early stage lung cancer – why do some patients not receive treatment with curative intent?

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Ross Lawrenson, Chunhuan Lao, Leonie Brown, Lucia Moosa, Lynne Chepulis, Rawiri Keenan, Jacquie Kidd, Karen Middleton, Paul Conaglen, Charles de Groot, Denise Aitken, Janice Wong

Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles

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Lixian Oh, Pierre Hainaut, Sandrine Blanchet, Hany Ariffin

Long-term outcomes and significance of preoperative lymphocyte-to-monocyte ratio as a prognostic indicator in patients with invasive pancreatic neoplasms after repeat pancreatectomy

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Shigetsugu Takano, Hideyuki Yoshitomi, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Takashi Mishima, Eri Nakadai, Masaru Miyazaki, Masayuki Ohtsuka

Production of an anti-angiogenic factor sFLT1 is suppressed via promoter hypermethylation of FLT1 gene in choriocarcinoma cells

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Tadashi Sasagawa, Atsushi Jinno-Oue, Takeshi Nagamatsu, Kazuki Morita, Tetsushi Tsuruga, Mayuyo Mori-Uchino, Tomoyuki Fujii, Masabumi Shibuya

Weight before and after a diagnosis of breast cancer or ductal carcinoma in situ: a national Australian survey

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Carolyn Ee, Adele Elizabeth Cave, Dhevaksha Naidoo, Kellie Bilinski, John Boyages

Plasma HER2ECD a promising test for patient prognosis and prediction of response in HER2 positive breast cancer: results of a randomized study - SAKK 22/99

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Serenella Eppenberger-Castori, Dirk Klingbiel, Thomas Ruhstaller, Daniel Dietrich, Daniel Alexander Rufle, Karin Rothgiesser, Olivia Pagani, Beat Thürlimann

A phase I/II study of weekly nab-paclitaxel plus cisplatin in chemotherapy-naïve patients with advanced non-small-cell lung cancer

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Yoshihiro Hattori, Yuko Kono, Shoichi Itoh, Takako Inoue, Yoshiko Urata, Yoshitaka Kawa, Rie Tohnai, Toru Kumagai, Kazumi Nishino, Ryuji Uozumi, Satoshi Morita, Shunichi Negoro, Fumio Imamura, Miyako Satouchi

Early onset neutropenia: a useful predictor of chemosensitivity and favorable prognosis in patients with serous ovarian cancer

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Yijing He, Ting Li, Jue Liu, Qiong Ou, Junlin Zhou

Development of a disease-specific graded prognostic assessment index for the management of sarcoma patients with brain metastases (Sarcoma-GPA)

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Anna Patrikidou, Loic Chaigneau, Nicolas Isambert, Kyriaki Kitikidou, Ryan Shanley, Isabelle Ray-Coquard, Thibaud Valentin, Bettina Malivoir, Maryline Laigre, Jacques-Olivier Bay, Laurence Moureau-Zabotto, Emmanuelle Bompas, Sophie Piperno-Neumann, Nicolas Penel, Thierry Alcindor, Cécile Guillemet, Florence Duffaud, Anne Hügli, Cécile Le Pechoux, Frédéric Dhermain, Jean-Yves Blay, Paul W. Sperduto, Axel Le Cesne

Shear wave elasticity by tracing total nodule showed high reproducibility and concordance with fibrosis in thyroid cancer

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Myung Hi Yoo, Hye Jeong Kim, In Ho Choi, Suyeon Park, Sang Jin Kim, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh

Potential biomarkers of ductal carcinoma in situ progression

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Raquel Spinassé Dettogni, Elaine Stur, Ana Carolina Laus, René Aloísio da Costa Vieira, Márcia Maria Chiquitelli Marques, Iara Viana Vidigal Santana, José Zago Pulido, Laura Fregonassi Ribeiro, Narelle de Jesus Parmanhani, Lidiane Pignaton Agostini, Raquel Silva dos Reis, Eldamária de Vargas Wolfgramm dos Santos, Lyvia Neves Rebello Alves, Fernanda Mariano Garcia, Jéssica Aflávio Santos, Diego do Prado Ventorim, Rui Manuel Reis, Iúri Drumond Louro

Serum levels of soluble programmed death-ligand 1 (sPD-L1) in patients with primary central nervous system diffuse large B-cell lymphoma

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Inju Cho, Hansang Lee, Sang Eun Yoon, Kyung Ju Ryu, Young Hyeh Ko, Won Seog Kim, Seok Jin Kim

EGFR modulates complement activation in head and neck squamous cell carcinoma

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Anas H. A. Abu-Humaidan, Lars Ekblad, Johan Wennerberg, Ole E. Sørensen

Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC) – a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)– the AIO/ CALGP/ ACO- GAIN-trial –

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• Study protocol

Thorsten O. Goetze, Wolf O. Bechstein, Ulli Simone Bankstahl, Tobias Keck, Alfred Königsrainer, Sven A. Lang, Claudia Pauligk, Pompiliu Piso, Arndt Vogel, Salah-Eddin Al-Batran

Short and long-term barriers and facilitators of skin self-examination among individuals diagnosed with melanoma

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Adina Coroiu, Chelsea Moran, Catherine Bergeron, Martin Drapeau, Beatrice Wang, Abbas Kezouh, Jochen Ernst, Gerald Batist, Annett Körner

Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer

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Yuanyuan Shen, Yue Guan, Justin J. Hummel, Chi-Ren Shyu, Jonathan B. Mitchem

Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial

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Anthony C. Nichols, Pencilla Lang, Eitan Prisman, Eric Berthelet, Eric Tran, Sarah Hamilton, Jonn Wu, Kevin Fung, John R. de Almeida, Andrew Bayley, David P. Goldstein, Antoine Eskander, Zain Husain, Houda Bahig, Apostolos Christopoulous, Michael Hier, Khalil Sultanem, Keith Richardson, Alex Mlynarek, Suren Krishnan, Hien Le, John Yoo, S. Danielle MacNeil, Adrian Mendez, Eric Winquist, Nancy Read, Varagur Venkatesan, Sara Kuruvilla, Andrew Warner, Sylvia Mitchell, Martin Corsten, Murali Rajaraman, Stephanie Johnson-Obaseki, Libni Eapen, Michael Odell, Shamir Chandarana, Robyn Banerjee, Joseph Dort, T. Wayne Matthews, Robert Hart, Paul Kerr, Samuel Dowthwaite, Michael Gupta, Han Zhang, Jim Wright, Christina Parker, Bret Wehrli, Keith Kwan, Julie Theurer, David A. Palma

Epigenetic loss of heterozygosity of Apc and an inflammation-associated mutational signature detected in Lrig1+/−-driven murine colonic adenomas

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Jessica L. Preston, Nicholas Stiffler

PD-L1 and CD4 are independent prognostic factors for overall survival in endometrial carcinomas

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Shuang Zhang, Takeo Minaguchi, Chenyang Xu, Nan Qi, Hiroya Itagaki, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Manabu Sakurai, Hiroyuki Ochi, Toyomi Satoh

Correction to: Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR)

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Igor Monsellato, Filippo Alongi, Elisa Bertocchi, Stefania Gori, Giacomo Ruffo, Elisa Cassinotti, Ludovica Baldari, Luigi Boni, Graziano Pernazza, Fabio Pulighe, Carlo De Nisco, Roberto Perinotti, Emilio Morpurgo, Tania Contardo, Enzo Mammano, Ugo Elmore, Roberto Delpini, Riccardo Rosati, Federico Perna, Andrea Coratti, Benedetta Menegatti, Sergio Gentilli, Paolo Baroffio, Piero Buccianti, Riccardo Balestri, Cristina Ceccarelli, Valter Torri, Davide Cavaliere, Leonardo Solaini, Giorgio Ercolani, Elena Traverso, Vittorio Fusco, Maura Rossi, Fabio Priora, G. Numico, Paola Franzone, Sara Orecchia

BRAF mutant colorectal cancer: ErbB2 expression levels as predictive factor for the response to combined BRAF/ErbB inhibitors

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Evelina Miele, Luana Abballe, Gian Paolo Spinelli, Zein Mersini Besharat, Giuseppina Catanzaro, Martina Chiacchiarini, Alessandra Vacca, Agnese Po, Carlo Capalbo, Elisabetta Ferretti

A phase-II/III randomized controlled trial of adjuvant radiotherapy or concurrent chemoradiotherapy after surgery versus surgery alone in patients with stage-IIB/III esophageal squamous cell carcinoma

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• Study protocol

Wenjie Ni, Shufei Yu, Wencheng Zhang, Zefen Xiao, Zongmei Zhou, Dongfu Chen, Qinfu Feng, Jun Liang, Jima Lv, Shugeng Gao, Yousheng Mao, Qi Xue, Kelin Sun, Xiangyang Liu, Dekang Fang, Jian Li, Dali Wang

Disease characteristics and treatment patterns of Chinese patients with metastatic colorectal cancer: a retrospective study using medical records from China

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Ruihua Xu, Wei Wang, Bo Zhu, Xiaoyan Lin, Dong Ma, Lingjun Zhu, Qingchuan Zhao, Yongzhan Nie, Xiaohong Cai, Qi Li, Weijia Fang, Hongyan Li, Ning Wang, Yun Chen, Cike Peng, Honghao Fang, Lin Shen

Predictive value of gamma-glutamyl transpeptidase to lymphocyte count ratio in hepatocellular carcinoma patients with microvascular invasion

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Hongxing Zhang, Yu Zhou, Yicheng Li, Wanying Qin, Yunhua Zi, Yulan Liu, Xiaoying Qiu, Hongyuan Xu, Weijia Liao, Zhaoquan Huang

Rectal aberrant crypt foci (ACF) as a predictor of benign and malignant neoplastic lesions in the large intestine

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Marek Kowalczyk, Marcin Orłowski, Łukasz Klepacki, Krzysztof Zinkiewicz, Waldemar Kurpiewski, Dorota Kaczerska, Wiesław Pesta, Ewa Zieliński, Piotr Siermontowski

Diffusion weighted magnetic resonance imaging (DW-MRI) as a non-invasive, tissue cellularity marker to monitor cancer treatment response

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Frederikke Petrine Fliedner, Trine Bjørnbo Engel, Henrik H. El-Ali, Anders Elias Hansen, Andreas Kjaer

Retrospective analysis of the immunogenic effects of intra-arterial locoregional therapies in hepatocellular carcinoma: a rationale for combining selective internal radiation therapy (SIRT) and immunotherapy

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Ligia Craciun, Roland de Wind, Pieter Demetter, Valerio Lucidi, Ali Bohlok, Sébastien Michiels, Fikri Bouazza, Michael Vouche, Ilario Tancredi, Gontran Verset, Soizic Garaud, Céline Naveaux, Maria Gomez Galdon, Karen Willard Gallo, Alain Hendlisz, Ivan Duran Derijckere, Patrick Flamen, Denis Larsimont, Vincent Donckier

Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database

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Guangfu Hu, Guangxia Hu, Chengjiao Zhang, Xiaoyan Lin, Ming Shan, Yanmin Yu, Yongwei Lu, Ruijie Niu, Hui Ye, Cheng Wang, Cheng Xu

Blood test shows high accuracy in detecting stage I non-small cell lung cancer

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Cherylle Goebel, Christopher L. Louden, Robert Mckenna Jr, Osita Onugha, Andrew Wachtel, Thomas Long

The kinetic profile and clinical implication of SCC-Ag in squamous cervical cancer patients undergoing radical hysterectomy using the Simoa assay: a prospective observational study

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Shuang Ye, Xiaohua Sun, Bin Kang, Fei Wu, Zhong Zheng, Libing Xiang, Mylène Lesénéchal, Fabienne Heskia, Ji Liang, Huijuan Yang

Trajectories of physical activity, from young adulthood to older adulthood, and pancreatic cancer risk; a population-based case-control study in Ontario, Canada

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Jaspreet Sandhu, Vanessa De Rubeis, Michelle Cotterchio, Brendan T. Smith, Lauren E. Griffith, Darren R. Brenner, Ayelet Borgida, Steven Gallinger, Sean Cleary, Laura N. Anderson

Impact of double J stenting or nephrostomy placement during transurethral resection of bladder tumour on the incidence of metachronous upper urinary tract urothelial cancer

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Marie C. Hupe, Lukas Dormayer, Tomasz Ozimek, Julian P. Struck, Martin J. P. Hennig, Melanie Klee, Christoph A. J. von Klot, Markus A. Kuczyk, Axel S. Merseburger, Mario W. Kramer

Integrative analysis of breast cancer profiles in TCGA by TNBC subgrouping reveals novel microRNA-specific clusters, including miR-17-92a, distinguishing basal-like 1 and basal-like 2 TNBC subtypes

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Karel Kalecky, Rebecca Modisette, Samantha Pena, Young-Rae Cho, Joseph Taube

Paravertebral catheter versus EPidural analgesia in Minimally invasive Esophageal resectioN: a randomized controlled multicenter trial (PEPMEN trial)

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B. F. Kingma, W. J. Eshuis, E. M. de Groot, M. L. Feenstra, J. P. Ruurda, S. S. Gisbertz, W. ten Hoope, M. Marsman, J. Hermanides, M. W. Hollmann, C. J. Kalkman, M. D. P. Luyer, G. A. P. Nieuwenhuijzen, H. J. Scholten, M. Buise, M. J. van Det, E. A. Kouwenhoven, F. van der Meer, G. W. J. Frederix, E. Cheong, K. al Naimi, M. I. van Berge Henegouwen, R. van Hillegersberg

miRNA expression profiling of hereditary breast tumors from BRCA1- and BRCA2-germline mutation carriers in Brazil

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Danielle Pessôa-Pereira, Adriane Feijó Evangelista, Rhafaela Lima Causin, René Aloisio da Costa Vieira, Lucas Faria Abrahão-Machado, Iara Viana Vidigal Santana, Vinicius Duval da Silva, Karen Cristina Borba de Souza, Renato José de Oliveira-Silva, Gabriela Carvalho Fernandes, Rui Manuel Reis, Edenir Inêz Palmero, Márcia Maria Chiquitelli Marques

Patterns of recurrence after surgery and efficacy of salvage therapy after recurrence in patients with thoracic esophageal squamous cell carcinoma

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Wenjie Ni, Jinsong Yang, Wei Deng, Zefen Xiao, Zongmei Zhou, Hongxing Zhang, Dongfu Chen, Qinfu Feng, Jun Liang, Jima Lv, Xiaozhen Wang, Xin Wang, Tao Zhang, Nan Bi, Lei Deng, Wenqing Wang

Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer

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Pranabananda Dutta, Lin Zhang, Huijun Zhang, Qin Peng, Phillippe R. Montgrain, Yingxiao Wang, Yuanlin Song, Jinghong Li, Willis X. Li

Nutritional assessment and prognosis of oral cancer patients: a large-scale prospective study

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Xiaodan Bao, Fengqiong Liu, Jing Lin, Qing Chen, Lin Chen, Fa Chen, Jing Wang, Yu Qiu, Bin Shi, Lizhen Pan, Lisong Lin, Baochang He

Stereotactic radiotherapy on brain metastases with recent hemorrhagic signal: STEREO-HBM, a two-step phase 2 trial

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Paul Lesueur, William Kao, Alexandra Leconte, Julien Geffrelot, Justine Lequesne, Joëlle Lacroix, Pierre-Emmanuel Brachet, Ioana Hrab, Philippe Royer, Bénédicte Clarisse, Dinu Stefan

Heterogeneous components of lung adenocarcinomas confer distinct EGFR mutation and PD-L1 expression

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Yiran Cai, Hongbo Wu, Xiaoqin Shi, Yujie Dong, Xiujun Chang, Li Zhang, Lijuan Zhou, Dan Su, Ming Yang

Necessity of prophylactic splenic hilum lymph node clearance for middle and upper third gastric cancer: a network meta-analysis

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Gaozan Zheng, Jinqiang Liu, Yinghao Guo, Fei Wang, Shushang Liu, Guanghui Xu, Man Guo, Xiao Lian, Hongwei Zhang, Fan Feng

Clinicopathological variables influencing overall survival, recurrence and post-recurrence survival in resected stage I non-small-cell lung cancer

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Chengdi Wang, Yuxuan Wu, Jun Shao, Dan Liu, Weimin Li

Temporal changes in gut microbiota profile in children with acute lymphoblastic leukemia prior to commencement-, during-, and post-cessation of chemotherapy

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Ling Ling Chua, Reena Rajasuriar, Yvonne Ai Lian Lim, Yin Ling Woo, P’ng Loke, Hany Ariffin

The institutional learning curve is associated with survival outcomes of robotic radical hysterectomy for early-stage cervical cancer-a retrospective study

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Kyung Jin Eoh, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim

A retrospective analysis on metastatic rate of the internal mammary lymph node and its clinical significance in adjuvant radiotherapy of breast cancer patients

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Li Li, Hongyan Zhang, Linwei Wang, Conghua Xie, Yunfeng Zhou, Yahua Zhong

A panel of protein kinase high expression is associated with postoperative recurrence in cholangiocarcinoma

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Sureerat Padthaisong, Malinee Thanee, Nisana Namwat, Jutarop Phetcharaburanin, Poramate Klanrit, Narong Khuntikeo, Attapol Titapun, Watcharin Loilome

Correlation of skin rash and overall survival in patients with pancreatic cancer treated with gemcitabine and erlotinib – results from a non-interventional multi-center study

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C. Benedikt Westphalen, Tobias Kukiolka, Benjamin Garlipp, Lars Hahn, Martin Fuchs, Peter Malfertheiner, Marcel Reiser, Fabian Kütting, Volker Heinemann, Andreas Beringer, Dirk T. Waldschmidt

Reduced doses of dabrafenib and trametinib combination therapy for BRAF V600E-mutant non-small cell lung cancer prevent rhabdomyolysis and maintain tumor shrinkage: a case report

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Yuta Adachi, Naohiro Yanagimura, Chiaki Suzuki, Sakiko Ootani, Azusa Tanimoto, Akihiro Nishiyama, Kaname Yamashita, Koushiro Ohtsubo, Shinji Takeuchi, Seiji Yano

Risk factors for severe rash with use of vemurafenib alone or in combination with cobimetinib for advanced melanoma: pooled analysis of clinical trials

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Ashley M. Hopkins, Akash D. Rathod, Andrew Rowland, Ganessan Kichenadasse, Michael J. Sorich

Efficacy and safety of bupropion in cancer-related fatigue, a randomized double blind placebo controlled clinical trial

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Ebrahim Salehifar, Saeid Azimi, Ghasem Janbabai, Ehsan Zaboli, Narjes Hendouei, Fatemeh Saghafi, Samaneh Borhani

Syntenin overexpression in human lung cancer tissue and serum is associated with poor prognosis

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Pengyong Luo, Xuli Yang, Shiren Huang, Shu Feng, Zongxing Ou

Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer

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Takaaki Oba, Kazuma Maeno, Daiya Takekoshi, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Ken-ichi Ito

GR, Sgk1, and NDRG1 in esophageal squamous cell carcinoma: their correlation with therapeutic outcome of neoadjuvant chemotherapy

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Shunsuke Ueki, Fumiyoshi Fujishima, Takuro Kumagai, Hirotaka Ishida, Hiroshi Okamoto, Kai Takaya, Chiaki Sato, Yusuke Taniyma, Takashi Kamei, Hironobu Sasano

Malignant mesothelioma of the tunica vaginalis testis: a rare case and review of literature

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• Case report

Mingaile Drevinskaite, Ausvydas Patasius, Lukas Kevlicius, Ugnius Mickys, Giedre Smailyte

Correction to: Comparison of two invitation-based methods for human papillomavirus (HPV) self-sampling with usual care among un- and under-screened Māori, Pacific and Asian women: study protocol for a randomised controlled community trial to examine the effect of self-sampling on participation in cervical-cancer screening

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Naomi Brewer, Karen Bartholomew, Anna Maxwell, Jane Grant, Georgina McPherson, Helen Wihongi, Collette Bromhead, Nina Scott, Sue Crengle, Chris Cunningham, Jeroen Douwes, John D. Potter

Correction to: Low-cost HPV testing and the prevalence of cervical infection in asymptomatic populations in Guatemala

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Hong Lou, Eduardo Gharzouzi, Sarita Polo Guerra, Joël Fokom Domgue, Julie Sawitzke, Guillermo Villagran, Lisa Garland, Joseph F. Boland, Sarah Wagner, Héctor Rosas, Jami Troxler, Heidi McMillen, Bailey Kessing, Enrique Alvirez, Miriam Castillo, Hesler Morales, Victor Argueta, Andert Rosingh, Femke J. H. B. van Aerde-van Nunen, Griselda Lopez, Herbert M. Pinedo, Mark Schiffman, Michael Dean, Roberto Orozco

Multiple m6A RNA methylation modulators promote the malignant progression of hepatocellular carcinoma and affect its clinical prognosis

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Nanfang Qu, Sanyu Qin, Xuemei Zhang, Xiaotong Bo, Zhengchun Liu, Chao Tan, Guiqiong Wen, Haixing Jiang

High thromboembolic event rate in patients with locally advanced oesophageal cancer during neoadjuvant therapy. An exploratory analysis of the prospective, randomised intergroup phase III trial SAKK 75/08

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Martin Fehr, Hanne Hawle, Stefanie Hayoz, Peter Thuss-Patience, Sabina Schacher, Jorge Riera Knorrenschild, Donat Dürr, Wolfram T. Knoefel, Holger Rumpold, Michael Bitzer, Martin Zweifel, Panagiotis Samaras, Ulrich Mey, Marc Küng, Ralph Winterhalder, Wolfgang Eisterer, Viviane Hess, Marie-Aline Gérard, Arnoud Templeton, Michael Stahl, Thomas Ruhstaller

Combination versus single-agent as palliative chemotherapy for gastric cancer

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Jin-Hyuk Choi, Yong Won Choi, Seok Yun Kang, Geum Sook Jeong, Hyun Woo Lee, Seong Hyun Jeong, Joon Seong Park, Mi Sun Ahn, Seung Soo Sheen

Correction to: Resectable pancreatic adenocarcinoma neo-adjuvant FOLF(IRIN)OX-based chemotherapy - a multicenter, non-comparative, randomized, phase II trial (PANACHE01-PRODIGE48 study)

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• Correction

Lilian Schwarz, Dewi Vernerey, Jean-Baptiste Bachet, Jean-Jacques Tuech, Fabienne Portales, Pierre Michel, Antonio Sa Cunha

Physical function in patients newly diagnosed with multiple myeloma; a Danish cohort study

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Rikke Faebo Larsen, Mary Jarden, Lisbeth Rosenbek Minet, Ulf Christian Frølund, Sören Möller, Niels Abildgaard

Bone complications in patients with multiple myeloma in five European countries: a retrospective patient chart review

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María-Victoria Mateos, Leah Fink, Niranchana Koneswaran, Michele Intorcia, Christina Giannopoulou, Daniela Niepel, Michele Cavo

Silica and asbestos exposure at work and the risk of bladder cancer in Canadian men: a population-based case-control study

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Lidija Latifovic, Paul J. Villeneuve, Marie-Élise Parent, Linda Kachuri, Farah McCrate, Ron Dewar, Nancy Kreiger, Donna Turner, Shelley A. Harris

Sarcopenia as a predictor of mortality in women with breast cancer: a meta-analysis and systematic review

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Xiao-Ming Zhang, Qing-Li Dou, Yingchun Zeng, Yunzhi Yang, Andy S. K. Cheng, Wen-Wu Zhang

Clinical significance of peripheral blood and tumor tissue lymphocyte subsets in cervical cancer patients

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Yutuan Wu, Shuang Ye, Shyamal Goswami, Xuan Pei, Libing Xiang, Xiaoming Zhang, Huijuan Yang

Incidence of advanced-stage breast cancer in regular participants of a mammography screening program: a prospective register-based study

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Laura Khil, Jan Heidrich, Ina Wellmann, Vanessa Kääb-Sanyal, Stefanie Weigel, Walter Heindel, Hans-Werner Hense, Oliver Heidinger

Increased PD-1-positive macrophages in the tissue of gastric cancer are closely associated with poor prognosis in gastric cancer patients

• Open Access
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Yusuke Kono, Hiroaki Saito, Wataru Miyauchi, Shota Shimizu, Yuki Murakami, Yuji Shishido, Kozo Miyatani, Tomoyuki Matsunaga, Yoji Fukumoto, Yuji Nakayama, Chiye Sakurai, Kiyotaka Hatsuzawa, Yoshiyuki Fujiwara

Relationship of lymphovascular invasion with lymph node metastasis and prognosis in superficial esophageal carcinoma: systematic review and meta-analysis

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Jinxin Yang, Zhouyi Lu, Lintao Li, Yong Li, Yulong Tan, Dekang Zhang, An Wang

Granulomatosis with polyangiitis in a patient treated with dabrafenib and trametinib for BRAF V600E positive lung adenocarcinoma

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• Case report

Anastasios Dimou, Gregory Barron, Daniel T. Merrick, Jason Kolfenbach, Robert C. Doebele

LncRNA SNHG5 promotes nasopharyngeal carcinoma progression by regulating miR-1179/HMGB3 axis

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Dengtao Liu, Yanpeng Wang, Yigang Zhao, Xiao Gu

Prognostic value of tumor-infiltrating lymphocytes in patients with triple-negative breast cancer: a systematic review and meta-analysis

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Guoxuan Gao, Zihan Wang, Xiang Qu, Zhongtao Zhang

Efficacy of bevacizumab combined with chemotherapy in the treatment of HER2-negative metastatic breast cancer: a network meta-analysis

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Zhengwu Sun, Xiaoyan Lan, Shizhao Xu, Shen Li, Yalin Xi

Lymph node metastasis in young and middle-aged papillary thyroid carcinoma patients: a SEER-based cohort study

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• Database

Yuanchao Liu, Yizeng Wang, Ke Zhao, Dongyang Li, Zuoyu Chen, Ruoyu Jiang, Xiaoning Wang, Xianghui He

Risk factors for aspiration pneumonia during concurrent chemoradiotherapy or bio-radiotherapy for head and neck cancer

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Hiromichi Shirasu, Tomoya Yokota, Satoshi Hamauchi, Yusuke Onozawa, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Keita Mori, Hirofumi Yasui

Serum miRNAs, a potential prognosis marker of loco-regionally advanced nasopharyngeal carcinoma patients treated with CCRT

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Zhimin Zhang, Jiangbiao Huang, Ge Wang, Feng Jin, Jijun Zheng, He Xiao, Lin Lei, Jia Luo, Chuan Chen

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo

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Anna Richter, Sina Sender, Annemarie Lenz, Rico Schwarz, Burkhard Hinz, Gudrun Knuebel, Anett Sekora, Hugo Murua Escobar, Christian Junghanss, Catrin Roolf

Germline BRCA, chemotherapy response scores, and survival in the neoadjuvant treatment of ovarian cancer

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Yong Jae Lee, Hyun-Soo Kim, John Hoon Rim, Jung-Yun Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim, Young Tae Kim

Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study

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Maidina Abudushataer, Noriko Sato, Makiko Mieno, Motoji Sawabe, Masaaki Muramatsu, Tomio Arai

Guy’s cancer cohort – real world evidence for cancer pathways

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C. Moss, A. Haire, F. Cahill, D. Enting, S. Hughes, D. Smith, E. Sawyer, A. Davies, J. Zylstra, K. Haire, A. Rigg, M. Van Hemelrijck

Validation and modification of staging Systems for Poorly Differentiated Pancreatic Neuroendocrine Carcinoma

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Haihong Wang, Zhenyu Lin, Guiling Li, Dejun Zhang, Dandan Yu, Qili Lin, Jing Wang, Ye Zhao, Guoliang Pi, Tao Zhang

Comparison of survival outcomes between radio-chemotherapy and radical hysterectomy with postoperative standard therapy in patients with stage IB1 to IIA2 cervical cancer: long-term oncological outcome analysis in 37 Chinese hospitals

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Ping Liu, Lihong Lin, Yanxiang Kong, Zhifeng Huo, Lin Zhu, Xiaonong Bin, Jinghe Lang, Chunlin Chen

Incidence and time trends of sarcoma (2000–2013): results from the French network of cancer registries (FRANCIM)

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Brice Amadeo, Nicolas Penel, Jean-Michel Coindre, Isabelle Ray-Coquard, Karine Ligier, Patricia Delafosse, Anne-Marie Bouvier, Sandrine Plouvier, Justine Gallet, Aude Lacourt, Gaëlle Coureau, Alain Monnereau, Simone Mathoulin-Pélissier, Emmanuel Desandes

Primary malignant pericardial tumour in Lynch syndrome

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Pasquale Paolisso, Giulia Saturi, Alberto Foà, Maristella Saponara, Margherita Nannini, Maria Abbondanza Pantaleo, Ornella Leone, Daniela Turchetti, Daniele Calistri, Carlo Savini, Davide Pacini, Carmine Pizzi, Nazzareno Galiè

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study

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Hiroomi Takayama, Masayuki Ohta, Yukio Iwashita, Hiroki Uchida, Yuki Shitomi, Kazuhiro Yada, Masafumi Inomata

Utility of magnetic resonance imaging in determining treatment response and local recurrence in nasopharyngeal carcinoma treated curatively

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Katherine Meng, Jeremy Tey, Francis Cho Hao Ho, Hira Asim, Timothy Cheo

Accuracy of detecting residual disease after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma (preSINO trial): a prospective multicenter diagnostic cohort study

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• Study protocol

Xiaobin Zhang, Ben M. Eyck, Yang Yang, Jun Liu, Yin-Kai Chao, Ming-Mo Hou, Tsung-Min Hung, Qingsong Pang, Zhen-Tao Yu, Hongjing Jiang, Simon Law, Ian Wong, Ka-On Lam, Berend J. van der Wilk, Ate van der Gaast, Manon C. W. Spaander, Roelf Valkema, Sjoerd M. Lagarde, Bas P. L. Wijnhoven, J. Jan B. van Lanschot, Zhigang Li

An unusual hematopoietic stem cell transplantation for donor acute lymphoblastic leukemia: a case report

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• Case report

Di Zhou, Ting Xie, Suning Chen, Yipeng Ling, Yueyi Xu, Bing Chen, Jian Ouyang, Yonggong Yang

Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series

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Ryota Tamura, Yukina Morimoto, Kenzo Kosugi, Mizuto Sato, Yumiko Oishi, Ryo Ueda, Ryogo Kikuchi, Hideaki Nagashima, Tetsuro Hikichi, Shinobu Noji, Yutaka Kawakami, Hikaru Sasaki, Kazunari Yoshida, Masahiro Toda

An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

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Ewa Przybytkowski, Thomas Davis, Abdelrahman Hosny, Julia Eismann, Ursula A. Matulonis, Gerburg M. Wulf, Sheida Nabavi

A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol

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• Study protocol

Nicholas F. Brown, Stasya M. Ng, Claire Brooks, Tim Coutts, Jane Holmes, Corran Roberts, Leena Elhussein, Peter Hoskin, Tim Maughan, Sarah Blagden, Paul Mulholland

Identification of potential novel biomarkers to differentiate malignant thyroid nodules with cytological indeterminate

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Dandan Wu, Shudong Hu, Yongzhong Hou, Yingying He, Shubai Liu

Lipid profile and risk of ovarian tumours: a meta-analysis

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Justina Ucheojor Onwuka, Akinkunmi Paul Okekunle, Olaniyi Matthew Olutola, Onoja Matthew Akpa, Rennan Feng

Changes in therapy and survival of metastatic renal cell carcinoma in Estonia

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Hannes Jürgens, Kristiina Ojamaa, Helis Pokker, Kaire Innos, Peeter Padrik

Alteration in the sensitivity to crizotinib by Na+/H+ exchanger regulatory factor 1 is dependent to its subcellular localization in ALK-positive lung cancers

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Fenglian Yang, Mu Hu, Siyuan Chang, Jing Huang, Yang Si, Jinghui Wang, Shan Cheng, Wen G. Jiang

Outcomes of patients with initially locally advanced pancreatic adenocarcinoma who did not benefit from resection: a prospective cohort study

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Jonathan Garnier, Jacques Ewald, Ugo Marchese, Marine Gilabert, Simon Launay, Laurence Moureau-Zabotto, Flora Poizat, Marc Giovannini, Jean-Robert Delpero, Olivier Turrini

Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer

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Kyung Jin Eoh, Hye Min Kim, Jung-Yun Lee, Sunghoon Kim, Sang Wun Kim, Young Tae Kim, Eun Ji Nam

A distinct molecular mutational profile and its clinical impact in essential thrombocythemia and primary myelofibrosis patients

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Uzma Zaidi, Gul Sufaida, Munazza Rashid, Bushra Kaleem, Sidra Maqsood, Samina Naz Mukry, Rifat Zubair Ahmed Khan, Saima Munzir, Munira Borhany, Tahir Sultan Shamsi

Identification of immune cells and mRNA associated with prognosis of gastric cancer

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Mingming Wang, Zedong Li, Yu Peng, Jianyu Fang, Tao Fang, Jiajia Wu, Jun Zhou

Dissociated responses at initial computed tomography evaluation is a good prognostic factor in non-small cell lung cancer patients treated with anti-programmed cell death-1/ligand 1 inhibitors

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Takehiro Tozuka, Satoru Kitazono, Hiroaki Sakamoto, Hiroshi Yoshida, Yoshiaki Amino, Shinya Uematsu, Takahiro Yoshizawa, Tsukasa Hasegawa, Ken Uchibori, Noriko Yanagitani, Atsushi Horiike, Takeshi Horai, Masahiro Seike, Akihiko Gemma, Makoto Nishio

Significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and prognostic nutritional index for predicting clinical outcomes in T1–2 rectal cancer

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Li-jian Xia, Wen Li, Jian-cheng Zhai, Chuan-wang Yan, Jing-bo Chen, Hui Yang

High tumor budding is a strong predictor of poor prognosis in the resected perihilar cholangiocarcinoma patients regardless of neoadjuvant therapy, showing survival similar to those without resection

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Takahiro Ito, Naohisa Kuriyama, Yuji Kozuka, Haruna Komatsubara, Ken Ichikawa, Daisuke Noguchi, Aoi Hayasaki, Tekehiro Fujii, Yusuke Iizawa, Hiroyuki Kato, Akihiro Tanemura, Yasuhiro Murata, Masashi Kishiwada, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Shuji Isaji

Correction to: A reactive oxygen species scoring system predicts cisplatin sensitivity and prognosis in ovarian cancer patients

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Chaoyang Sun, Ensong Guo, Bo Zhou, Wanying Shan, Jia Huang, Danhui Weng, Peng Wu, Changyu Wang, Shixuan Wang, Wei Zhang, Qinglei Gao, Xiaoyan Xu, Beibei Wang, Junbo Hu, Ding Ma, Gang Chen

Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing

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Honghong Zhang, Hongsheng Wang, Xiaowen Qian, Shuai Gao, Jieqi Xia, Junwen Liu, Yanqin Cheng, Jie Man, Xiaowen Zhai

Mutational landscape differences between young-onset and older-onset breast cancer patients

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Nicole E. Mealey, Dylan E. O’Sullivan, Joy Pader, Yibing Ruan, Edwin Wang, May Lynn Quan, Darren R. Brenner

Tumor mutational burden is associated with poor outcomes in diffuse glioma

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Lihong Wang, Jia Ge, Yang Lan, Yu Shi, Ying Luo, Yuhuan Tan, Mei Liang, Song Deng, Xia Zhang, Wenying Wang, Yaoyao Tan, Yuanyuan Xu, Tao Luo

Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma

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Jiangqiao Zhou, Tianyu Wang, Tao Qiu, Zhongbao Chen, Xiaoxiong Ma, Long Zhang, Jilin Zou

Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report

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• Case report

Andrew D. Simmons, Minh Nguyen, Elias Pintus

Prognostic significance of stem cell/ epithelial-mesenchymal transition markers in periampullary/pancreatic cancers: FGFR1 is a promising prognostic marker

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Yosep Chong, Nishant Thakur, Kwang Yeol Paik, Eun Jung Lee, Chang Suk Kang

Elastin is a key factor of tumor development in colorectal cancer

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Jinzhi Li, Xiaoyue Xu, Yanyan Jiang, Nicole G. Hansbro, Philip M. Hansbro, Jincheng Xu, Gang Liu

Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma

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Ratakorn Srisuttee, Areeya Arayataweegool, Patnarin Mahattanasakul, Napadon Tangjaturonrasme, Virachai Kerekhanjanarong, Somboon Keelawat, Apiwat Mutirangura, Nakarin Kitkumthorn

Pazopanib versus sunitinib in Chinese patients with locally advanced or metastatic renal cell carcinoma: pooled subgroup analysis from the randomized, COMPARZ studies

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Xinan Sheng, Jie Jin, Zhisong He, Yiran Huang, Aiping Zhou, Jinwan Wang, Xiubao Ren, Dingwei Ye, Xu Zhang, Shukui Qin, Fangjian Zhou, Binhui Wang, Jun Guo

Adult primary testicular lymphoma: clinical features and survival in a series of patients treated at a high-volume institution in China

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Bo Chen, De-Hong Cao, Li Lai, Jian-Bing Guo, Ze-Yu Chen, Yin Huang, Shi Qiu, Tian-Hai Lin, Yue Gou, Na Ma, Lu Yang, Liang-Ren Liu, Qiang Wei

Correction to: Increased MiR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro

• Open Access
• Correction

Minhua Rong, Gang Chen, Yiwu Dang

HOXB4 promotes the malignant progression of ovarian cancer via DHDDS

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Na Li, Jin-hai Gou, Jiao Xiong, Juan-juan You, Zheng-yu Li

Study protocol: a randomized controlled trial comparing the efficacy of therapist guided internet-delivered cognitive therapy (TG-iConquerFear) with augmented treatment as usual in reducing fear of cancer recurrence in Danish colorectal cancer survivors

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• Study protocol

Johanne Dam Lyhne, Allan ‘ Ben’ Smith, Lisbeth Frostholm, Per Fink, Lars Henrik Jensen

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): dragon II trial

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Maneesh Kumarsing Beeharry, Zhen-Tian Ni, Zhong Yin Yang, Ya Nan Zheng, Run Hua Feng, Wen-Tao Liu, Chao Yan, Xue Xin Yao, Chen Li, Min Yan, Zheng-Gang Zhu

P16 as a marker of carcinoma in effusions and peritoneal washing

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Fabiana Pirani Carneiro, Rivadávio Fernandes Amorim, Marcos de Vasconcelos Carneiro, Tercia Maria Mendes Lousa de Castro, Leonora Maciel de Souza Vianna, Gustavo Henrique Soares Takano, Andersen Charles Daros, Isabela Peres, Selma Aparecida Souza Kuckelhaus, Andrea Barretto Motoyama

Different ODE models of tumor growth can deliver similar results

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• Technical advance

James A. Koziol, Theresa J. Falls, Jan E. Schnitzer

A convolutional neural network-based system to classify patients using FDG PET/CT examinations

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Keisuke Kawauchi, Sho Furuya, Kenji Hirata, Chietsugu Katoh, Osamu Manabe, Kentaro Kobayashi, Shiro Watanabe, Tohru Shiga

Age-related differences in breast cancer mortality according to race/ethnicity, insurance, and socioeconomic status

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Yazmin San Miguel, Scarlett Lin Gomez, James D. Murphy, Richard B. Schwab, Corinne McDaniels-Davidson, Alison J. Canchola, Alfredo A. Molinolo, Jesse N. Nodora, Maria Elena Martinez

Immunological effects of nivolumab immunotherapy in patients with oral cavity squamous cell carcinoma

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Ying Xiong, David M. Neskey, Joshua D. Horton, Chrystal M. Paulos, Hannah M. Knochelmann, Kent E. Armeson, M. Rita I. Young

Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation

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Ronja Morsch, Michael Rose, Angela Maurer, Maria Angela Cassataro, Till Braunschweig, Ruth Knüchel, Thomas-Alexander Vögeli, Thorsten Ecke, Markus Eckstein, Veronika Weyerer, Irene Esposito, Maximilian Ackermann, Günter Niegisch, Nadine T. Gaisa, Michael Rose, Ruth Knüchel, Thorsten Ecke, Nadine T. Gaisa

Study protocol: watchful observation of patients with limited small cell lung cancer instead of the PCI—prospective, multi-center one-arm study

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• Study protocol

Sergiusz Nawrocki, Anna Sugajska

Netupitant/palonosetron (NEPA) and dexamethasone for prevention of emesis in breast cancer patients receiving adjuvant anthracycline plus cyclophosphamide: a multi-cycle, phase II study

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Roberta Caputo, Marina Elena Cazzaniga, Andrea Sbrana, Rosalba Torrisi, Ida Paris, Monica Giordano, Vincenzo Montesarchio, Valentina Guarneri, Laura Amaducci, Domenico Bilancia, Giuseppina Cilenti, Alessandra Fabi, Elena Collovà, Alessio Schirone, Erminio Bonizzoni, Luigi Celio, Sabino De Placido, Michelino De Laurentiis

Huge aneurysmal bone cyst secondary to giant cell tumor of the hand phalanx: a case report and related literature

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• Case report

Mingzhuo Li, Yaokai Gan, Dingwei Shi, Jie Zhao

MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case-control study in a population from North Sardinia

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Matteo Floris, Daria Sanna, Paolo Castiglia, Carlo Putzu, Valeria Sanna, Antonio Pazzola, Maria Rosaria De Miglio, Francesca Sanges, Giovanna Pira, Antonio Azara, Emanuele Lampis, Antonello Serra, Ciriaco Carru, Maristella Steri, Flavia Costanza, Marco Bisail, Maria Rosaria Muroni

Roles of neutrophil/lymphocyte ratio in prognosis and in differentiation of potential beneficiaries in HER2-positive breast cancer with trastuzumab therapy

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Nianhua Ding, Juan Huang, Ningsha Li, Jiaqi Yuan, Shouman Wang, Zhi Xiao

Retraction Note: Correlation of CD44v6 expression with ovarian cancer progression and recurrence

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• Retraction Note

Jun Shi, Zhou Zhou, Wen Di, Ningli Li

MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index

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Hanne Due, Rasmus Froberg Brøndum, Ken H. Young, Martin Bøgsted, Karen Dybkær

Prognostic value of the bone scan index in patients with metastatic castration-resistant prostate cancer: a systematic review and meta-analysis

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Hualin Song, Song Jin, Peng Xiang, Shuai Hu, Jie Jin

Neck lymph node metastasis detection in patients with differentiated thyroid carcinoma (DTC) in long-term follow-up: a 131I-SPECT/CT study

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Angela Spanu, Susanna Nuvoli, Andrea Marongiu, Ilaria Gelo, Luciana Mele, Bastiana Piras, Giuseppe Madeddu

CD3+T-lymphocyte infiltration is an independent prognostic factor for advanced nasopharyngeal carcinoma

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Nasser Al-Rajhi, Hussein Soudy, Shoaib A. Ahmed, Tusneem Elhassan, Shamayel F. Mohammed, Hatim A. Khoja, Hazem Ghebeh

Expression and clinical significance of miR-4516 and miR-21-5p in serum of patients with colorectal cancer

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Xi-Han Jin, Sen Lu, Ai-Fen Wang

Identification of microRNAs and their Endonucleolytic Cleavaged target mRNAs in colorectal cancer

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Fangbin Zhou, Donge Tang, Yong Xu, Huiyan He, Yan Wu, Liewen Lin, Jun Dong, Wenyong Tan, Yong Dai

Clinical characteristics and risk factors of 47 cases with ruptured neuroblastoma in children

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Hong Qin, Shen Yang, Siyu Cai, Qinghua Ren, Wei Han, Wei Yang, Haiyan Cheng, Xiaoli Ma, Huanmin Wang

Clinical features and survival of pregnancy-associated breast cancer: a retrospective study of 203 cases in China

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Bo-yue Han, Xiao-guang Li, Hai-yun Zhao, Xin Hu, Hong Ling

Challenges in the cultural adaptation of the German Myeloma Patient Outcome Scale (MyPOS): an outcome measure to support routine symptom assessment in myeloma care

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Christina Gerlach, Katherine Taylor, Marion Ferner, Markus Munder, Martin Weber, Christina Ramsenthaler

Population-based SEER analysis of survival in colorectal cancer patients with or without resection of lung and liver metastases

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Alexander R. Siebenhüner, Ulrich Güller, Rene Warschkow

European women’s perceptions of the implementation and organisation of risk-based breast cancer screening and prevention: a qualitative study

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Linda Rainey, Daniëlle van der Waal, Anna Jervaeus, Louise S. Donnelly, D. Gareth Evans, Mattias Hammarström, Per Hall, Yvonne Wengström, Mireille J. M. Broeders

Clinicopathologic features and genomic analysis of pulmonary blastomatoid carcinosarcoma

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Jikai Zhao, Chan Xiang, Ruiying Zhao, Ping Guo, Jingjing Zheng, Han Han-Zhang, Keke Yu, Jie Zhang, Yuchen Han

Longitudinal trajectory patterns of plasma albumin and C-reactive protein levels around diagnosis, relapse, bacteraemia, and death of acute myeloid leukaemia patients

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Kim Oren Gradel, Pedro Póvoa, Olav Sivertsen Garvik, Pernille Just Vinholt, Stig Lønberg Nielsen, Thøger Gorm Jensen, Ming Chen, Ram Benny Dessau, Jens Kjølseth Møller, John Eugenio Coia, Pernille Sanberg Ljungdalh, Annmarie Touborg Lassen, Henrik Frederiksen

Comorbidity in lung cancer patients and its association with medical service cost and treatment choice in China

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Ruoxi Ding, Dawei Zhu, Ping He, Yong Ma, Zhishui Chen, Xuefeng Shi

RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

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Heidi G. Parker, Deepika Dhawan, Alex C. Harris, Jose A. Ramos-Vara, Brian W. Davis, Deborah W. Knapp, Elaine A. Ostrander

Change in public awareness of colorectal cancer symptoms following the Be Cancer Alert Campaign in the multi-ethnic population of Malaysia

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Désirée Schliemann, Darishiani Paramasivam, Maznah Dahlui, Christopher R. Cardwell, Saunthari Somasundaram, Nor Saleha Binti Ibrahim Tamin, Conan Donnelly, Tin Tin Su, Michael Donnelly

Risk factor analysis for inaccurate pre-operative MRI staging in rectal cancer

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Zerong Cai, Xiaoyu Xie, Yufeng Chen, Zexian Chen, Wuteng Cao, Khamis Salem Saeed Saad, Yifeng Zou, Ping Lan, Xiaojian Wu

Using digital health to facilitate compliance with standardized pediatric cancer treatment guidelines in Tanzania: protocol for an early-stage effectiveness-implementation hybrid study

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• Study protocol

Lavanya Vasudevan, Kristin Schroeder, Yadurshini Raveendran, Kunal Goel, Christina Makarushka, Nestory Masalu, Leah L. Zullig

Lapatinib in combination with capecitabine versus continued use of trastuzumab in breast cancer patients with trastuzumab-resistance: a retrospective study of a Chinese population

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Fan Yang, Xiang Huang, Chunxiao Sun, Jianbin Li, Biyun Wang, Min Yan, Feng Jin, Haibo Wang, Jin Zhang, Peifen Fu, Tianyu Zeng, Jian Wang, Wei Li, Yongfei Li, Mengzhu Yang, Jun Li, Hao Wu, Ziyi Fu, Yongmei Yin, Zefei Jiang

The first pancreatic neuroendocrine tumor in Li-Fraumeni syndrome: a case report

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• Case report

John G. Aversa, Francine Blumental De Abreu, Sho Yano, Liqiang Xi, Donald W. Hadley, Irini Manoli, Mark Raffeld, Samira M. Sadowski, Naris Nilubol

CD8-positive memory T cells in tumor-draining lymph nodes of patients with breast cancer

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Yasmin Vahidi, Mandana Bagheri, Abbas Ghaderi, Zahra Faghih

Long non-coding RNA AFAP1-AS1 accelerates the progression of melanoma by targeting miR-653-5p/RAI14 axis

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Fei Liu, Lanting Hu, Yi Pei, Ke Zheng, Wei Wang, Shenglong Li, Enduo Qiu, Guanning Shang, Jiaming Zhang, Xiaojing Zhang

Quality of life study of patients with unresectable locally advanced or metastatic pancreatic adenocarcinoma treated with gemcitabine+nab-paclitaxel versus gemcitabine alone: AX-PANC-SY001, a randomized phase-2 study

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Suayib Yalcin, Faysal Dane, Berna Oksuzoglu, Nuriye Yildirim Ozdemir, Abdurrahman Isikdogan, Metin Ozkan, Guzin Gonullu Demirag, Hasan Senol Coskun, Bulent Karabulut, Turkkan Evrensel, Mehmet Ali Ustaoglu, Feyyaz Ozdemir, Hande Turna, Tugba Yavuzsen, Faruk Aykan, Alper Sevinc, Hakan Akbulut, Deniz Yuce, Mutlu Hayran, Saadettin Kilickap

Real-world treatment and survival of patients with advanced non-small cell lung Cancer: a German retrospective data analysis

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Fränce Hardtstock, David Myers, Tracy Li, Diana Cizova, Ulf Maywald, Thomas Wilke, Frank Griesinger

Downregulation of S100 calcium binding protein A12 inhibits the growth of glioma cells

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Chunhe Lu, Jia Liu, Mingze Yao, Lun Li, Guangyu Li

CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A

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Nuo Xu, Fanglei Liu, Shengdi Wu, Maosong Ye, Haiyan Ge, Meiling Zhang, Yuanlin Song, Lin Tong, Jian Zhou, Chunxue Bai

Impact of individual background on the unmet needs of cancer survivors and caregivers – a mixed-methods analysis

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Kaname Watanabe, Kayoko Katayama, Takashi Yoshioka, Hiroto Narimatsu

The A818–6 system as an in-vitro model for studying the role of the transportome in pancreatic cancer

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Doaa Tawfik, Angela Zaccagnino, Alexander Bernt, Monika Szczepanowski, Wolfram Klapper, Albrecht Schwab, Holger Kalthoff, Anna Trauzold

In silico analysis of the immune microenvironment in bladder cancer

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Ye Zhang, De-hua Ou, Dong-wu Zhuang, Ze-feng Zheng, Ming-en Lin

A key genomic signature associated with lymphovascular invasion in head and neck squamous cell carcinoma

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Jian Zhang, Huaming Lin, Huali Jiang, Hualong Jiang, Tao Xie, Baiyao Wang, Xiaoting Huang, Jie Lin, Anan Xu, Rong Li, Jiexia Zhang, Yawei Yuan

Evaluation of cinnamon extract effects on clbB gene expression and biofilm formation in Escherichia coli strains isolated from colon cancer patients

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Faezah Kosari, Mohammad Taheri, Abbas Moradi, Reza Hakimi Alni, Mohammad Yousef Alikhani

Phase II, multi-center, open-label, single-arm clinical trial evaluating the efficacy and safety of Mycophenolate Mofetil in patients with high-grade locally advanced or metastatic osteosarcoma (ESMMO): rationale and design of the ESMMO trial

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• Study protocol

Nut Koonrungsesomboon, Nuttapong Ngamphaiboon, Natavudh Townamchai, Pimpisa Teeyakasem, Chaiyut Charoentum, Pimlak Charoenkwan, Rungrote Natesirinilkul, Lalita Sathitsamitphong, Touch Ativitavas, Parunya Chaiyawat, Jeerawan Klangjorhor, Suradej Hongeng, Dumnoensun Pruksakorn

Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma

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Priya Sriskandarajah, Alexis De Haven Brandon, Kenneth MacLeod, Neil O. Carragher, Vladimir Kirkin, Martin Kaiser, Steven R. Whittaker

Perineural invasion as a prognostic factor for intrahepatic cholangiocarcinoma after curative resection and a potential indication for postoperative chemotherapy: a retrospective cohort study

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Zeyu Zhang, Yufan Zhou, Kuan Hu, Dong Wang, Zhiming Wang, Yun Huang

Searching for novel multimodal treatments in oligometastatic pancreatic cancer

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• Case report

D. M. Filippini, E. Grassi, A. Palloni, R. Carloni, R. Casadei, C. Ricci, C. Serra, G. Ercolani, G. Brandi, M. Di Marco

Stem/progenitor cell marker expression in clear cell renal cell carcinoma: a potential relationship with the immune microenvironment to be explored

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Ju-Yoon Yoon, Craig Gedye, Joshua Paterson, Laurie Ailles

Synergistic enhancement of efficacy of platinum drugs with verteporfin in ovarian cancer cells

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Venkata Ramesh Dasari, David J. Carey, Radhika Gogoi

Value of digital mammography in predicting lymphovascular invasion of breast cancer

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Zhuangsheng Liu, Ruqiong Li, Keming Liang, Junhao Chen, Xiangmeng Chen, Xiaoping Li, Ronggang Li, Xin Zhang, Lilei Yi, Wansheng Long

Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer

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Mercedes Delgado-García, Birgit Weynand, Lourdes Gómez-Izquierdo, María José Hernández, Ángela María Blanco, Mar Varela, Xavier Matias-Guiu, Ernest Nadal, Bélgica Márquez-Lobo, Ana Alarcão, Enrique de Álava, Michele Biscuola

Long-term survival trends in patients with unresectable stage III non-small cell lung cancer receiving chemotherapy and radiation therapy: a SEER cancer registry analysis

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Ryan N. Hansen, Yiduo Zhang, Brian Seal, Kellie Ryan, Candice Yong, Annie Darilay, Scott D. Ramsey

PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma

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Motomasa Furuse, Hiroko Kuwabara, Naokado Ikeda, Yasuhiko Hattori, Tomotsugu Ichikawa, Naoki Kagawa, Kenichiro Kikuta, Sho Tamai, Mitsutoshi Nakada, Toshihiko Wakabayashi, Masahiko Wanibuchi, Toshihiko Kuroiwa, Yoshinobu Hirose, Shin-Ichi Miyatake

Efficacy and safety of concurrent chemoradiotherapy in ECOG 2 patients with locally advanced non-small-cell lung cancer: a subgroup analysis of a randomized phase III trial

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Nan Bi, Lipin Liu, Jun Liang, Shixiu Wu, Ming Chen, Changxing Lv, Lujun Zhao, Anhui Shi, Wei Jiang, Yaping Xu, Zongmei Zhou, Jingbo Wang, Wenqing Wang, Dongfu Chen, Zhouguang Hui, Jima Lv, Hongxing Zhang, Qinfu Feng, Zefen Xiao, Xin Wang, Tao Zhang, Weibo Yin, Junling Li, Jie He, Luhua Wang

Minocycline prevents and repairs the skin disorder associated with afatinib, one of the epidermal growth factor receptor-tyrosine kinase inhibitors for non-small cell lung cancer

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Kazumi Sano, Kazuhiko Nakadate, Kazuhiko Hanada

Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China

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Ruiqing Ma, Bing Wang, Xichao Zhai, Yiyan Lu, Hongbin Xu

Landscape of copy number aberrations in esophageal squamous cell carcinoma from a high endemic region of South Africa

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Jacqueline Brown, Andrzej J. Stepien, Pascale Willem

lncRNA CRNDE promotes the proliferation and metastasis by acting as sponge miR-539-5p to regulate POU2F1 expression in HCC

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Zhixi Li, Gang Wu, Jie Li, Youyu Wang, Xueming Ju, Wenjun Jiang

Patterns of regional lymph node failure of locally advanced hypopharyngeal squamous cell carcinoma after first-line treatment with surgery and/or intensity-modulated radiotherapy

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Dongqing Wang, Shui Yu, Limin Zhai, Jin Xu, Baosheng Li

Racial differences in testicular cancer in the United States: descriptive epidemiology

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Yang Li, Qi Lu, Yu Wang, Shuangge Ma

CD45dimCD34+CD38−CD133+ cells have the potential as leukemic stem cells in acute myeloid leukemia

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Sook-Kyoung Heo, Eui-Kyu Noh, Lan Jeong Ju, Jun Young Sung, Yoo Kyung Jeong, Jaekyung Cheon, Su Jin Koh, Young Joo Min, Yunsuk Choi, Jae-Cheol Jo

Final results from IMPROVE: a randomized, controlled, open-label, two-arm, cross-over phase IV study to determine patients’ preference for everolimus in combination with exemestane or capecitabine in combination with bevacizumab in advanced HR-positive, HER2-negative breast cancer

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Thomas Decker, Ulrike Söling, Antje Hahn, Christoph Maintz, Christian Martin Kurbacher, Ursula Vehling-Kaiser, Dagmar Sent, Peter Klare, Volker Hagen, Marco Chiabudini, Julia Falkenstein, Martin Indorf, Eva Runkel, Karin Potthoff

Dietary factors and risk of mortality among patients with esophageal cancer: a systematic review

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Li-Ping Sun, Lu-Bin Yan, Zhen-Zhen Liu, Wen-Jing Zhao, Cai-Xia Zhang, Yu-Min Chen, Xiang Qian Lao, Xudong Liu

Trends in the epidemiology of young-onset colorectal cancer: a worldwide systematic review

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Khalid Saad El Din, Jonathan M. Loree, Eric C. Sayre, Sharlene Gill, Carl J. Brown, Hallie Dau, Mary A. De Vera

Overexpression of SLC6A1 associates with drug resistance and poor prognosis in prostate cancer

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Chaojiang Chen, Zhiduan Cai, Yangjia Zhuo, Ming Xi, Zhuoyuan Lin, Funeng Jiang, Zezhen Liu, Yueping Wan, Yu Zheng, Jianxin Li, Xing Zhou, Jianguo Zhu, Weide Zhong

The DNA hypermethylation phenotype of colorectal cancer liver metastases resembles that of the primary colorectal cancers

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Stephany Orjuela, Mirco Menigatti, Peter Schraml, Patryk Kambakamba, Mark D. Robinson, Giancarlo Marra

Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material

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• Technical advance

Elisabeth M. P. Steeghs, Leonie I. Kroeze, Bastiaan B. J. Tops, Leon C. van Kempen, Arja ter Elst, Annemiek W. M. Kastner-van Raaij, Sandra J. B. Hendriks-Cornelissen, Mandy J. W. Hermsen, Erik A. M. Jansen, Petra M. Nederlof, Ed Schuuring, Marjolijn J. L. Ligtenberg, Astrid Eijkelenboom

Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis

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Neal Shah, Zhongwei Liu, Rachel M. Tallman, Afroz Mohammad, Samuel A. Sprowls, Pushkar A. Saralkar, Schuyler D. Vickers, Mark V. Pinti, Weimin Gao, Paul R. Lockman

HPV E6 and E7 oncoproteins cooperatively alter the expression of Disc Large 1 polarity protein in epithelial cells

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María Paula Dizanzo, Federico Marziali, Clarisse Brunet Avalos, Marina Bugnon Valdano, Santiago Leiva, Ana Laura Cavatorta, Daniela Gardiol

Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism

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Giselle M. Faria, Igor D. P. Soares, Marcela D’Alincourt Salazar, Marcia R. Amorim, Bruno L. Pessoa, Clovis O. da Fonseca, Thereza Quirico-Santos

Trend of disparity between coastland and inland in medical expenditure burden for rural inpatients with malignant tumor in southeast of China from 2007 to 2016

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Rong Fu, Zheng Lin, Fei He, Yixian Jiang, Zhenquan Zheng, Zhijian Hu

Health behaviors of caregivers of childhood cancer survivors: a cross-sectional study

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In Young Cho, Nack-Gyun Chung, Hee Jo Baek, Ji Won Lee, Ki Woong Sung, Dong Wook Shin, Jung Eun Yoo, Yun-Mi Song

Sequential analysis of transcript expression patterns improves survival prediction in multiple cancers

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Jordan Mandel, Raghunandan Avula, Edward V. Prochownik

Screening differentially expressed genes of pancreatic cancer between Mongolian and Han people using bioinformatics technology

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Jiasheng Xu, Kaili Liao, Zhonghua Fu, Zhenfang Xiong

RIPK1 polymorphisms alter the susceptibility to cervical Cancer among the Uyghur population in China

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Zulipiyamu Tuoheti, Lili Han, Sulaiya Husaiyin, Xiaoxi Liu, Chunhua Ma, Mayinuer Niyazi

Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect

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J. Boegeholz, C. S. Brueggen, C. Pauli, F. Dimitriou, E. Haralambieva, R. Dummer, M. G. Manz, C. C. Widmer

Correction to: Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series

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• Correction

Ryota Tamura, Yukina Morimoto, Kenzo Kosugi, Mizuto Sato, Yumiko Oishi, Ryo Ueda, Ryogo Kikuchi, Hideaki Nagashima, Tetsuro Hikichi, Shinobu Noji, Yutaka Kawakami, Hikaru Sasaki, Kazunari Yoshida, Masahiro Toda

Impact of nuclear YAP1 expression in residual cancer after neoadjuvant chemohormonal therapy with docetaxel for high-risk localized prostate cancer

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Yoshinori Matsuda, Shintaro Narita, Taketoshi Nara, Huang Mingguo, Hiromi Sato, Atsushi Koizumi, Sohei Kanda, Kazuyuki Numakura, Mitsuru Saito, Takamitsu Inoue, Yuko Hiroshima, Hiroshi Nanjo, Shigeru Satoh, Norihiko Tsuchiya, Tomonori Habuchi

Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced oesophageal squamous cell carcinoma: a single-Centre, open-label, randomized, controlled, clinical trial (HCHTOG1903)

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• Study protocol

Hai-Bo Sun, Wen-Qun Xing, Xian-Ben Liu, Yan Zheng, Shu-Jun Yang, Zong-Fei Wang, Shi-Lei Liu, Yu-Feng Ba, Rui-Xiang Zhang, Bao-Xing Liu, Cheng-Cheng Fan, Pei-Nan Chen, Guang-Hui Liang, Yong-Kui Yu, Qi Liu, Hao-Ran Wang, Hao-Miao Li, Zhen-Xuan Li

Real-world comparative effectiveness of second-line ipilimumab for metastatic melanoma: a population-based cohort study in Ontario, Canada

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Wei Fang Dai, Jaclyn M. Beca, Ruth Croxford, Wanrudee Isaranawatchai, Ines B. Menjak, Teresa M. Petrella, Nicole Mittmann, Craig C. Earle, Scott Gavura, Timothy P. Hanna, Kelvin K.W. Chan

INHBA is a prognostic predictor for patients with colon adenocarcinoma

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Xueying Li, Weiming Yu, Chao Liang, Yuan Xu, Miaozun Zhang, Xiaoyun Ding, Xianlei Cai

Gastrointestinal peptides in children before and after hematopoietic stem cell transplantation

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Szymon Skoczeń, Magdalena Rej, Kinga Kwiecińska, Danuta Pietrys, Przemysław J. Tomasik, Małgorzata Wójcik, Wojciech Strojny, Agnieszka Dłużniewska, Katarzyna Klimasz, Kamil Fijorek, Michał Korostyński, Marcin Piechota, Walentyna Balwierz

Computational models applied to metabolomics data hints at the relevance of glutamine metabolism in breast cancer

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Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Elena López-Camacho, Guillermo Prado-Vázquez, Andrea Zapater-Moros, Rocío López-Vacas, Jorge M. Arevalillo, Mariana Díaz-Almirón, Hilario Navarro, Paloma Maín, Enrique Espinosa, Pilar Zamora, Juan Ángel Fresno Vara

Chemotherapy, host response and molecular dynamics in periampullary cancer: the CHAMP study

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Sofie Olsson Hau, Alexandra Petersson, Björn Nodin, Emelie Karnevi, Karolina Boman, Caroline Williamsson, Jakob Eberhard, Karin Leandersson, David Gisselsson, Margareta Heby, Karin Jirström

Sepsis-associated pathways segregate cancer groups

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Himanshu Tripathi, Samanwoy Mukhopadhyay, Saroj Kant Mohapatra

The risks of ubiquinone and β-carotene deficiency and metabolic disorders in patients with oral cancer

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Man-Yee Chan, Bor-Jen Lee, Po-Sheng Chang, Han-Yu Hsiao, Li-Ping Hsu, Chia-Hua Chang, Ping-Ting Lin

Unexpected response to palliative radiotherapy for subcutaneous metastases of an advanced small cell pancreatic neuroendocrine carcinoma: a case report of two different radiation schedules

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• Case report

Maria Paola Ciliberti, Roberta Carbonara, Antonietta Grillo, Anna Maria Leo, Ivan Lolli, Carmela Ostuni, Laura Troiani, Barbara Turi, Simona Vallarelli, Angela Sardaro

The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10

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Xue Yang, Siting Li, Ying Wu, Feng Ge, Ying Chen, Qian Xiong

Identification of CELSR2 as a novel prognostic biomarker for hepatocellular carcinoma

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Mingxing Xu, Shu Zhu, Ruiyun Xu, Nan Lin

Deconvolution of diffuse gastric cancer and the suppression of CD34 on the BALB/c nude mice model

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Seon-Jin Yoon, Jungmin Park, Youngmin Shin, Yuna Choi, Sahng Wook Park, Seok-Gu Kang, Hye Young Son, Yong-Min Huh

All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells

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Wenxiu Yao, Liyang Wang, Huan Huang, Xin Li, Pinjia Wang, Kun Mi, Jia Cheng, Huifen Liu, Cuirong Gu, Lingxiao Huang, Jianming Huang

Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer

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Han Na Kang, Jae-Hwan Kim, A-Young Park, Jae Woo Choi, Sun Min Lim, Jinna Kim, Eun Joo Shin, Min Hee Hong, Kyoung-Ho Pyo, Mi Ran Yun, Dong Hwi Kim, Hanna Lee, Sun Och Yoon, Da Hee Kim, Young Min Park, Hyung Kwon Byeon, Inkyung Jung, Soonmyung Paik, Yoon Woo Koh, Byoung Chul Cho, Hye Ryun Kim

Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression

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Kavitha Mukund, Natalia Syulyukina, Sonia Ramamoorthy, Shankar Subramaniam

Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma

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Bingqi Ma, Huijuan Meng, Ye Tian, Yingying Wang, Tianqiang Song, Ti Zhang, Qiang Wu, Yunlong Cui, Huikai Li, Wei Zhang, Qiang Li

Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency

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Tomoyuki Nakajima, Takeshi Uehara, Mai Iwaya, Yukihiro Kobayashi, Yasuhiro Maruyama, Hiroyoshi Ota

Fertility sparing surgery vs radical surgery for epithelial ovarian cancer: a meta-analysis of overall survival and disease-free survival

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Denghua Liu, Jing Cai, Aiwei Gao, Zehua Wang, Liqiong Cai

Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PRE-HIIT): protocol for a randomized controlled trial

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Gráinne Sheill, Emer Guinan, Linda O’Neill, Charles Normand, Suzanne L. Doyle, Sarah Moore, John Newell, Grainne McDermott, Ronan Ryan, John V. Reynolds, Juliette Hussey

Feasibility of multi-parametric magnetic resonance imaging combined with machine learning in the assessment of necrosis of osteosarcoma after neoadjuvant chemotherapy: a preliminary study

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Bingsheng Huang, Jifei Wang, Meili Sun, Xin Chen, Danyang Xu, Zi-Ping Li, Jinting Ma, Shi-Ting Feng, Zhenhua Gao

3’UTR polymorphism of Thymidylate Synthase gene increased the risk of persistence of pre-neoplastic cervical lesions

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Nayara Nascimento Toledo Silva, Ana Carolina Silva Santos, Verlândia Mendes Nogueira, Cláudia Martins Carneiro, Angélica Alves Lima

Both comorbidity and worse performance status are associated with poorer overall survival after external beam radiotherapy for prostate cancer

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Miikka Lehtonen, Lauri Heiskanen, Petri Reinikainen, Pirkko-Liisa Kellokumpu-Lehtinen

Taxane-induced sensory peripheral neuropathy is associated with an SCN9A single nucleotide polymorphism in Japanese patients

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Yuko Tanabe, Seiji Shiraishi, Kenji Hashimoto, Kazutaka Ikeda, Daisuke Nishizawa, Junko Hasegawa, Akihiko Shimomura, Yukinori Ozaki, Nobuko Tamura, Mayu Yunokawa, Kan Yonemori, Toshimi Takano, Hidetaka Kawabata, Kenji Tamura, Yasuhiro Fujiwara, Chikako Shimizu

Treatment-related changes in neuroendocrine tumors as assessed by textural features derived from 68Ga-DOTATOC PET/MRI with simultaneous acquisition of apparent diffusion coefficient

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Manuel Weber, Lukas Kessler, Benedikt Schaarschmidt, Wolfgang Peter Fendler, Harald Lahner, Gerald Antoch, Lale Umutlu, Ken Herrmann, Christoph Rischpler

Comment on ‘comparison of overall survival and perioperative outcomes of laparoscopic pancreaticoduodenectomy and open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a systematic review and meta-analysis’

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Rui Sun, Yifan Zhang, Zhe Su

Prognostic value of TP53 concurrent mutations for EGFR- TKIs and ALK-TKIs based targeted therapy in advanced non-small cell lung cancer: a meta-analysis

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Kang Qin, Helei Hou, Yu Liang, Xiaochun Zhang

Microarray data analysis on gene and miRNA expression to identify biomarkers in non-small cell lung cancer

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Xiang Jin, Yinghui Guan, Zhen Zhang, Hongyue Wang

Applied anatomy of pelvic lymph nodes and its clinical significance for prostate cancer:a single-center cadaveric study

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Jia-Jun Chen, Zai-Sheng Zhu, Yi-Yi Zhu, Hong-Qi Shi

Retrospective analysis of salvage surgery for local progression of brain metastasis previously treated with stereotactic irradiation: diagnostic contribution, functional outcome, and prognostic factors

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Koichi Mitsuya, Yoko Nakasu, Nakamasa Hayashi, Shoichi Deguchi, Takuma Oishi, Takashi Sugino, Kazuaki Yasui, Hirofumi Ogawa, Tsuyoshi Onoe, Hirofumi Asakura, Hideyuki Harada

Modulation of SIRT3 expression through CDK4/6 enhances the anti-cancer effect of sorafenib in hepatocellular carcinoma cells

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Hanhee Jo, Yusun Park, Taehun Kim, Jisu Kim, Jong Sook Lee, Seon Yoo Kim, Jee-in Chung, Hae yong Ko, Jae-Chul Pyun, Kyung Sik Kim, Misu Lee, Mijin Yun

GRP78 expression in peripheral blood mononuclear cells is a new predictive marker for the benefit of taxanes in breast cancer neoadjuvant treatment

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Annat Raiter, Julia Lipovetzki, Ido Lubin, Rinat Yerushalmi

Hospitalization and definitive radiotherapy in lung cancer: incidence, risk factors and survival impact

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Sarah Z. Hazell, Nicholas Mai, Wei Fu, Chen Hu, Cole Friedes, Alex Negron, Khinh Ranh Voong, Josephine L. Feliciano, Peijin Han, Samantha Myers, Todd R. McNutt, Russell K. Hales

Prevalence and significance of potential drug-drug interactions among cancer patients receiving chemotherapy

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Mohammad Ismail, Sehrash Khan, Fahadullah Khan, Sidra Noor, Hira Sajid, Shazia Yar, Irum Rasheed

TENERGY: multicenter phase II study of Atezolizumab monotherapy following definitive Chemoradiotherapy with 5-FU plus Cisplatin in patients with unresectable locally advanced esophageal squamous cell carcinoma

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• Study protocol

Hideaki Bando, Daisuke Kotani, Takahiro Tsushima, Hiroki Hara, Shigenori Kadowaki, Ken Kato, Keisho Chin, Kensei Yamaguchi, Shun-ichiro Kageyama, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana, Masashi Wakabayashi, Miki Fukutani, Yosuke Togashi, Nozomu Fuse, Hiroyoshi Nishikawa, Takashi Kojima

Cardiovascular disease events within 5 years after a diagnosis of breast cancer

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Benoîte Mery, Antoine Fouilloux, Elise Rowinski, Judith Catella-Chatron, Jean-Baptiste Guichard, Antoine Da Costa, Fabien Tinquaut, N. Magné, Laurent Bertoletti

Retrospective observational study of salvage line ramucirumab monotherapy for patients with advanced gastric cancer

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Sadayuki Kawai, Naoki Fukuda, Shun Yamamoto, Seiichiro Mitani, Katsuhiro Omae, Takeru Wakatsuki, Ken Kato, Shigenori Kadowaki, Daisuke Takahari, Narikazu Boku, Kei Muro, Nozomu Machida

Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib

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Marjut Niinivirta, Maria Georganaki, Gunilla Enblad, Cecilia Lindskog, Anna Dimberg, Gustav J. Ullenhag

Tumor characteristics, treatments, and survival outcomes in prostate cancer patients with a PSA level < 4 ng/ml: a population-based study

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Zhibo Zheng, Zhien Zhou, Weigang Yan, Yi Zhou, Chuyan Chen, Hanzhong Li, Zhigang Ji

Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population

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Chuanyin Li, Yaheng Li, Zhiling Yan, Shuying Dai, Shuyuan Liu, Xia Wang, Jun Wang, Xinwen Zhang, Li Shi, Yufeng Yao

Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial

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Arwa Ali, Monica Dumbrava, Kylie Riddell, Nina Stewart, Robyn Ward, Ahmed K. Ibrahim, Melvin Chin

Clinicopathological and prognostic value of SNHG6 in cancers: a systematic review and a meta-analysis

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Shuo Zhang, Dandan Qiu, Xiaohong Xie, Yong Shen

Cytology cell blocks from malignant pleural effusion are good candidates for PD-L1 detection in advanced NSCLC compared with matched histology samples

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Yinying Zou, Liming Xu, Qiusu Tang, Qihan You, Xiaoling Wang, Wei Ding, Jing Zhao, Guoping Ren

Broadening risk profile in familial colorectal cancer type X; increased risk for five cancer types in the national Danish cohort

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Christina Therkildsen, Maria Rasmussen, Lars Smith-Hansen, Thomas Kallemose, Lars Joachim Lindberg, Mef Nilbert

Plasmacytoma in patients with multiple myeloma: morphology and immunohistochemistry

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Maiia V. Firsova, Larisa P. Mendeleeva, Alla M. Kovrigina, Maxim V. Solovev, Valery G. Savchenko

Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer

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Anne Marie McCarthy, Nitya Pradeep Kumar, Wei He, Susan Regan, Michaela Welch, Beverly Moy, A. John Iafrate, Andrew T. Chan, Aditya Bardia, Katrina Armstrong

Prognostic implications of Fibroblast growth factor receptor 1 (FGFR1) gene amplification and protein overexpression in hypopharyngeal and laryngeal squamous cell carcinoma

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Eun Kyung Kim, Yoon Ah Cho, Yoon Woo Koh, Hyang Ae Shin, Byoung Chul Cho, Sun Och Yoon

Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

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K. Harpelunde Poulsen, J. E. Nielsen, B. Grønkær Toft, U. N. Joensen, L. J. Rasmussen, M. Blomberg Jensen, R. T. Mitchell, A. Juul, E. Rajpert-De Meyts, A. Jørgensen

Altered ARID1A expression in colorectal cancer

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Mehran Erfani, Seyed Vahid Hosseini, Maral Mokhtari, Mozhdeh Zamani, Kamran Tahmasebi, Mahvash Alizadeh Naini, Alireza Taghavi, John M. Carethers, Minoru Koi, Hassan Brim, Pooneh Mokarram, Hassan Ashktorab

Factors influencing quality of life, function, reintegration and participation after musculoskeletal tumour operations

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Wolfram Weschenfelder, Sabine Gast-Froehlich, Christian Spiegel, Matthias Vogt, Gunther O. Hofmann

Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial

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Stefano Kim, Bruno Buecher, Thierry André, Marine Jary, François-Clément Bidard, François Ghiringhelli, Éric François, Julien Taieb, Denis Smith, Christelle de la Fouchardière, Jérôme Desramé, Emmanuelle Samalin, Aurélie Parzy, Nabil Baba-Hamed, Olivier Bouché, David Tougeron, Laëtitia Dahan, Farid El Hajbi, Marion Jacquin, Magali Rebucci-Peixoto, Laurie Spehner, Véronique Vendrely, Dewi Vernerey, Christophe Borg

Low-dose peripheral blood stem cell graft after high-dose chemotherapy - an evaluation of hematopoietic reconstitution

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Sandra Sauer, Petra Pavel, Anita Schmitt, Martin Cremer, Mark Kriegsmann, Thomas Bruckner, Karin Jordan, Patrick Wuchter, Carsten Müller-Tidow, Katharina Kriegsmann

Enhanced antitumor efficacy in colon cancer using EGF functionalized PLGA nanoparticles loaded with 5-Fluorouracil and perfluorocarbon

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Pingping Wu, Qing Zhou, Huayun Zhu, Yan Zhuang, Jun Bao

Higher number of multidisciplinary tumor board meetings per case leads to improved clinical outcome

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Marius Freytag, Ulrich Herrlinger, Stefan Hauser, Franz G. Bauernfeind, Maria A. Gonzalez-Carmona, Jennifer Landsberg, Jens Buermann, Hartmut Vatter, Tobias Holderried, Thorsten Send, Martin Schumacher, Arne Koscielny, Georg Feldmann, Mario Heine, Dirk Skowasch, Niklas Schäfer, Benjamin Funke, Michael Neumann, Ingo G. H. Schmidt-Wolf

EGFR mutation testing and treatment decisions in patients progressing on first- or second-generation epidermal growth factor receptor tyrosine kinase inhibitors

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Anne C. Chiang, Ancilla W. Fernandes, Melissa Pavilack, Jennifer W. Wu, François Laliberté, Mei Sheng Duh, Nabil Chehab, Janakiraman Subramanian

Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer

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Hansong Du, Jia Yang, Ying Zhang

Clinical utility of polyethylene glycol conjugated granulocyte colony-stimulating factor (PEG-G-CSF) for preventing severe neutropenia in metastatic colorectal cancer patients treated with FOLFOXIRI plus bevacizumab: a single-center retrospective study

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Yusuke Kitagawa, Hiroki Osumi, Eiji Shinozaki, Yumiko Ota, Izuma Nakayama, Takeshi Suzuki, Takeru Wakatsuki, Mariko Ogura, Akira Ooki, Daisuke Takahari, Mitsukuni Suenaga, Keisho Chin, Kensei Yamaguchi

Anti-HER2 induced myeloid cell alterations correspond with increasing vascular maturation in a murine model of HER2+ breast cancer

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Meghan J. Bloom, Angela M. Jarrett, Todd A. Triplett, Anum K. Syed, Tessa Davis, Thomas E. Yankeelov, Anna G. Sorace

SIP SMART: a parallel group randomised feasibility trial of a tailored pre-treatment swallowing intervention package compared with usual care for patients with head and neck cancer

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Roganie Govender, Christina H. Smith, Helen Barratt, Benjamin Gardner, Stuart A. Taylor

Pretreatment elevated prognostic nutritional index predicts a favorable prognosis in patients with prostate cancer

• Open Access
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Bin Li, Zheng Lu, Shengzheng Wang, Junqing Hou, Gang Xia, Heng Li, Bo Yin, Wei Lu

Efficacy of PSMA ligand PET-based radiotherapy for recurrent prostate cancer after radical prostatectomy and salvage radiotherapy

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Ann-Kathrin Oehus, Stephanie G. C. Kroeze, Nina-Sophie Schmidt-Hegemann, Marco M. E. Vogel, Simon Kirste, Jessica Becker, Irene A. Burger, Thorsten Derlin, Peter Bartenstein, Matthias Eiber, Michael Mix, Christian la Fougère, Claus Belka, Stephanie E. Combs, Anca-Ligia Grosu, Arndt-Christian Müller, Matthias Guckenberger, Hans Christiansen, Christoph Henkenberens

The neutrophil/lymphocyte ratio as a predictor of successful conversion surgery for stage IV gastric cancer: a retrospective study

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Naohiko Nakamura, Shinichi Kinami, Yasuto Tomita, Takashi Miyata, Hideto Fujita, Hiroyuki Takamura, Nobuhiko Ueda, Takeo Kosaka

Identifying opportunities to support patient-centred care for ductal carcinoma in situ: qualitative interviews with clinicians

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Bryanna B. Nyhof, Frances C. Wright, Nicole J. Look Hong, Gary Groot, Lucy Helyer, Pamela Meiers, May Lynn Quan, Nancy N. Baxter, Robin Urquhart, Rebecca Warburton, Anna R. Gagliardi

Moderate to vigorous physical activity participation associated with better quality of life among breast and colorectal cancer survivors in Korea

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Ji-Hye Park, Dong Hoon Lee, Seung Il Kim, Nam Kyu Kim, Justin Y. Jeon

Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples

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Cleo Keppens, Elisabeth M. C. Dequeker, Etienne Rouleau, Nils ’t Hart, Lukas Bubendorf, Kelly Dufraing, Céline Garrec, Paul Guéguen, Aude Lamy, Antonio Marchetti, Patrick Pauwels, Ales Ryska, Véronique Tack, Luigi Tornillo, Kaat Van Casteren, Jan H. von der Thüsen, Karen Zwaenepoel, Birgit Lissenberg-Witte, Erik Thunnissen, Ed Schuuring

Design of a randomized controlled trial of a partnership-based, needs-tailored self-management support intervention for post-treatment breast cancer survivors

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• Study protocol

Soo Hyun Kim, Yu Hyeon Choe, Ah Reum Han, Gwui Jeong Yeon, Gyeong Hee Lee, Bo Gyeong Lee, Young Up Cho, Seho Park, Moon Hee Lee

Evaluation of the expression levels of BRAFV600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay

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Tien Viet Tran, Kien Xuan Dang, Quynh Huong Pham, Ung Dinh Nguyen, Nhung Thi Trang Trinh, Luong Van Hoang, Son Anh Ho, Ba Van Nguyen, Duc Trong Nguyen, Dung Tuan Trinh, Dung Ngoc Tran, Arto Orpana, Ulf-Håkan Stenman, Jakob Stenman, Tho Huu Ho

Germline whole exome sequencing of a family with appendiceal mucinous tumours presenting with pseudomyxoma peritonei

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Mei Sim Lung, Catherine A. Mitchell, Maria A. Doyle, Andrew C. Lynch, Kylie L. Gorringe, David D. L. Bowtell, Ian G. Campbell, Alison H. Trainer

A phase II study of Osimertinib for patients with radiotherapy-naïve CNS metastasis of non-small cell lung cancer: treatment rationale and protocol design of the OCEAN study (LOGIK 1603/WJOG 9116L)

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• Study protocol

Kazushige Wakuda, Hiroyuki Yamaguchi, Hirotsugu Kenmotsu, Minoru Fukuda, Masafumi Takeshita, Takayuki Suetsugu, Keisuke Kirita, Noriyuki Ebi, Osamu Hataji, Satoru Miura, Kenji Chibana, Isamu Okamoto, Kenichi Yoshimura, Kazuhiko Nakagawa, Nobuyuki Yamamoto, Kenji Sugio

Quantification of the individual risk of each Gleason pattern, including tertiary Gleason pattern 5, after radical prostatectomy: development of the modified Gleason grade grouping (mGGG) model

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Satoru Taguchi, Yukari Uemura, Tetsuya Fujimura, Teppei Morikawa, Akihiro Naito, Taketo Kawai, Motofumi Suzuki, Haruki Kume, Hiroshi Fukuhara

Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma

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Qiongzhen Chen, Jinmeng Li, Xiaoning Yang, Junfeng Ma, Fanghua Gong, Yu Liu

A population-based survey to assess the association between cannabis and quality of life among colorectal cancer survivors

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Susan L. Calcaterra, Andrea N. Burnett-Hartman, J. David Powers, Douglas A. Corley, Carmit M. McMullen, Pamala A. Pawloski, Heather Spencer Feigelson

FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

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Shika Hanif Malgundkar, Ikram Burney, Mansour Al Moundhri, Moza Al Kalbani, Ritu Lakhtakia, Aikou Okamoto, Yahya Tamimi

NAD(P)-dependent steroid dehydrogenase-like is involved in breast cancer cell growth and metastasis

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So-Hyun Yoon, Hoe Suk Kim, Ryong Nam Kim, So-Youn Jung, Bok Sil Hong, Eun Ji Kang, Han-Byoel Lee, Hyeong-Gon Moon, Dong-Young Noh, Wonshik Han

LncRNA SNHG7 promotes the proliferation of nasopharyngeal carcinoma by miR-514a-5p/ELAVL1 axis

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Weiqun Hu, Haolin Li, Shaozhong Wang

MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers

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Nina Gran Egeland, Kristin Jonsdottir, Miriam Ragle Aure, Kristine Sahlberg, Vessela N. Kristensen, Deirdre Cronin-Fenton, Ivar Skaland, Einar Gudlaugsson, Jan P. A. Baak, Emiel A. M. Janssen

The role of SRGN in the survival and immune infiltrates of skin cutaneous melanoma (SKCM) and SKCM-metastasis patients

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Xiaofang Wang, Hui Xiong, Daning Liang, Zhenzhen Chen, Xiqing Li, Kun Zhang

A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

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Kazuhiro Tanaka, Masanori Kawano, Tatsuya Iwasaki, Ichiro Itonaga, Hiroshi Tsumura

Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial

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• Study protocol

Robert Olson, Lindsay Mathews, Mitchell Liu, Devin Schellenberg, Benjamin Mou, Tanya Berrang, Stephen Harrow, Rohann J. M. Correa, Vasudeva Bhat, Howard Pai, Islam Mohamed, Stacy Miller, Famke Schneiders, Joanna Laba, Derek Wilke, Sashendra Senthi, Alexander V. Louie, Anand Swaminath, Anthony Chalmers, Stewart Gaede, Andrew Warner, Tanja D. de Gruijl, Alison Allan, David A. Palma

Cisplatin-based chemotherapy with or without bevacizumab for Chinese postmenopausal women with advanced cervical cancer: a retrospective observational study

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Xiaoli He, Jun Liu, Li Xiao, Mingdong Zhao, Tingting Su, Tiejian Liu, Guowei Han, Yue Wang

The prognostic value of preoperative fibrinogen-to-prealbumin ratio and a novel FFC score in patients with resectable gastric cancer

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Shuli Tang, Lin Lin, Jianan Cheng, Juan Zhao, Qijia Xuan, Jiayue Shao, Yang Zhou, Yanqiao Zhang

Inferring the role of the microbiome on survival in patients treated with immune checkpoint inhibitors: causal modeling, timing, and classes of concomitant medications

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Daniel Spakowicz, Rebecca Hoyd, Mitchell Muniak, Marium Husain, James S. Bassett, Lei Wang, Gabriel Tinoco, Sandip H. Patel, Jarred Burkart, Abdul Miah, Mingjia Li, Andrew Johns, Madison Grogan, David P. Carbone, Claire F. Verschraegen, Kari L. Kendra, Gregory A. Otterson, Lang Li, Carolyn J. Presley, Dwight H. Owen

Impact of the comprehensive geriatric assessment on treatment decision in geriatric oncology

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Sandrine Sourdet, Delphine Brechemier, Zara Steinmeyer, Stephane Gerard, Laurent Balardy

Reduction of cycles of neoadjuvant chemotherapy for advanced epithelial ovarian, fallopian or primary peritoneal cancer (ROCOCO): study protocol for a phase III randomized controlled trial

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• Study protocol

Soo Jin Park, Seung-Hyuk Shim, Yong-Il Ji, Sang-Hoon Kwon, Eun Ji Lee, Maria Lee, Suk Joon Chang, Samina Park, Sang Youn Kim, Sung Jong Lee, Jae-Weon Kim, Ju-Won Roh, San Hui Lee, Taejong Song, Hee Seung Kim

Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling

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Ruey-Shyang Soong, Ravi K. Anchoori, Richard B. S. Roden, Rou-Ling Cho, Yi-Chan Chen, Sheng-Chieh Tseng, Yun-Li Huang, Po-Cheng Liao, Yu-Chiau Shyu

ALDH1A3 serves as a predictor for castration resistance in prostate cancer patients

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Shangqian Wang, Xiang Zhou, Chao Liang, Meiling Bao, Ye Tian, Jundong Zhu, Tongtong Zhang, Jie Yang, Zengjun Wang

Integrated analysis of genome-wide miRNAs and targeted gene expression in esophageal squamous cell carcinoma (ESCC) and relation to prognosis

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Howard Yang, Hua Su, Nan Hu, Chaoyu Wang, Lemin Wang, Carol Giffen, Alisa M. Goldstein, Maxwell P. Lee, Philip R. Taylor

Metastatic breast cancer patient perceptions of somatic tumor genomic testing

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Elizabeth J. Adams, Sarah Asad, Raquel Reinbolt, Katharine A. Collier, Mahmoud Abdel-Rasoul, Susan Gillespie, James L. Chen, Mathew A. Cherian, Anne M. Noonan, Sagar Sardesai, Jeffrey VanDeusen, Robert Wesolowski, Nicole Williams, Charles L. Shapiro, Erin R. Macrae, Robert Pilarski, Amanda E. Toland, Leigha Senter, Bhuvaneswari Ramaswamy, Clara N. Lee, Maryam B. Lustberg, Daniel G. Stover

Construction of an integrated human osteosarcoma database, HOsDb, based on literature mining, microarray analysis, and database retrieval

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Yifu Sun, Lishan Wang, Changkuan Li, Rui Gu, Weidong Zang, Wei Song, Peng Xia

The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer

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Nerina C. van der Merwe, Jaco Oosthuizen, Magdalena Theron, George Chong, William D. Foulkes

Primary surgery versus no surgery in synchronous metastatic breast cancer: patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial

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V. Bjelic-Radisic, F. Fitzal, M. Knauer, G. Steger, D. Egle, R. Greil, P. Schrenk, M. Balic, Ch. Singer, R. Exner, L. Soelkner, Michael Gnant

The efficacy and safety of induction chemotherapy combined with concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients: a systematic review and meta-analysis

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Bi-Cheng Wang, Bo-Ya Xiao, Guo-He Lin, Chang Wang, Quentin Liu

Spatial patterns in prostate Cancer-specific mortality in Pennsylvania using Pennsylvania Cancer registry data, 2004–2014

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Ming Wang, Emily Wasserman, Nathaniel Geyer, Rachel M. Carroll, Shanshan Zhao, Lijun Zhang, Raymond Hohl, Eugene J. Lengerich, Alicia C. McDonald

Development and validation of a five-immune gene prognostic risk model in colon cancer

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Haitao Chen, Jun Luo, Jianchun Guo

Clinical validation of full genotyping CLART® HPV4S assay on SurePath and ThinPrep collected screening samples according to the international guidelines for human papillomavirus test requirements for cervical screening

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Ditte Møller Ejegod, Camilla Lagheden, Ramya Bhatia, Helle Pedersen, Elia Alcañiz Boada, Karin Sundström, Javier Cortés, F. Xavier Bosch Josë, Kate Cuschieri, Joakim Dillner, Jesper Bonde

The effects of combination treatments on drug resistance in chronic myeloid leukaemia: an evaluation of the tyrosine kinase inhibitors axitinib and asciminib

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H. Jonathan G. Lindström, Ran Friedman

Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

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Eric T. Miller, Sungyong You, Radu M. Cadaneanu, Minhyung Kim, Junhee Yoon, Sandy T. Liu, Xinmin Li, Lorna Kwan, Jennelle Hodge, Michael J. Quist, Catherine S. Grasso, Michael S. Lewis, Beatrice S. Knudsen, Michael R. Freeman, Isla P. Garraway

Head and neck cancer patients’ preferences for individualized prognostic information: a focus group study

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Arta Hoesseini, Emilie A. C. Dronkers, Aniel Sewnaik, Jose A. U. Hardillo, Robert J. Baatenburg de Jong, Marinella P. J. Offerman

Colorectal carcinomas with mucinous differentiation are associated with high frequent mutation of KRAS or BRAF mutations, irrespective of quantity of mucinous component

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Xiaodong Li, Katherine Sun, Xiaoyan Liao, Haijuan Gao, Hongfa Zhu, Ruliang Xu

Are cancer patients better off if they participate in clinical trials? A mixed methods study

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Zandra Engelbak Nielsen, Stefan Eriksson, Laurine Bente Schram Harsløf, Suzanne Petri, Gert Helgesson, Margrete Mangset, Tove E. Godskesen

Stereotactic robotic body radiotherapy for patients with oligorecurrent pulmonary metastases

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Patrick Berkovic, Akos Gulyban, Gilles Defraene, Laurie Swenen, David Dechambre, Paul Viet Nguyen, Nicolas Jansen, Carole Mievis, Pierre Lovinfosse, Levente Janvary, Maarten Lambrecht, Gert De Meerleer

Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma

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Deke Jiang, Jiaen Deng, Changzheng Dong, Xiaopin Ma, Qianyi Xiao, Bin Zhou, Chou Yang, Lin Wei, Carly Conran, S. Lilly Zheng, Irene Oi-lin Ng, Long Yu, Jianfeng Xu, Pak C. Sham, Xiaolong Qi, Jinlin Hou, Yuan Ji, Guangwen Cao, Miaoxin Li

Radiosurgery and fractionated stereotactic body radiotherapy for patients with lung oligometastases

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Goda G. Kalinauskaite, Ingeborg I. Tinhofer, Markus M. Kufeld, Anne A. Kluge, Arne A. Grün, Volker V. Budach, Carolin C. Senger, Carmen C. Stromberger

Neoadjuvant chemotherapy followed by curative-intent surgery for perihilar cholangiocarcinoma based on its anatomical resectability classification and lymph node status

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Naohisa Kuriyama, Masanobu Usui, Kazuaki Gyoten, Aoi Hayasaki, Takehiro Fujii, Yusuke Iizawa, Hiroyuki Kato, Yasuhiro Murata, Akihiro Tanemura, Masashi Kishiwada, Hiroyuki Sakurai, Shugo Mizuno, Shuji Isaji

PEACE V – Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM): a study protocol for a randomized controlled phase II trial

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• Study protocol

A. De Bruycker, A. Spiessens, P. Dirix, N. Koutsouvelis, I. Semac, N. Liefhooghe, A. Gomez-Iturriaga, W. Everaerts, F. Otte, A. Papachristofilou, M. Scorsetti, M. Shelan, S. Siva, F. Ameye, M. Guckenberger, R. Heikkilä, P. M. Putora, A. Zapatero, A. Conde-Moreno, F. Couñago, F. Vanhoutte, E. Goetghebeur, D. Reynders, T. Zilli, P. Ost

Clinical characteristics and prognostic factors of Hurthle cell carcinoma: a population based study

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Xingtong Zhou, Zhibo Zheng, Chuyan Chen, Bangbo Zhao, Hongtao Cao, Tianhao Li, Xudong Liu, Weibin Wang, Yongning Li

Mutational spectrum of acquired resistance to reversible versus irreversible EGFR tyrosine kinase inhibitors

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Svenja Wagener-Ryczek, Carina Heydt, Juliane Süptitz, Sebastian Michels, Markus Falk, Christina Alidousty, Jana Fassunke, Michaela Angelika Ihle, Markus Tiemann, Lukas Heukamp, Jürgen Wolf, Reinhard Büttner, Sabine Merkelbach-Bruse

Association of DNA repair gene variants with colorectal cancer: risk, toxicity, and survival

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Hamideh Salimzadeh, Elinor Bexe Lindskog, Bengt Gustavsson, Yvonne Wettergren, David Ljungman

Perioperative imaging in patients treated with resection of brain metastases: a survey by the European Association of Neuro-Oncology (EANO) Youngsters committee

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Barbara Kiesel, Carina M. Thomé, Tobias Weiss, Asgeir S. Jakola, Amélie Darlix, Alessia Pellerino, Julia Furtner, Johannes Kerschbaumer, Christian F. Freyschlag, Wolfgang Wick, Matthias Preusser, Georg Widhalm, Anna S. Berghoff

CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model

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Hidenori Tsukui, Hisanaga Horie, Koji Koinuma, Hideyuki Ohzawa, Yasunaru Sakuma, Yoshinori Hosoya, Hironori Yamaguchi, Kotaro Yoshimura, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama

Cancer incidence attributable to tuberculosis in 2015: global, regional, and national estimates

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Chi Yan Leung, Hsi-Lan Huang, Md. Mizanur Rahman, Shuhei Nomura, Sarah Krull Abe, Eiko Saito, Kenji Shibuya

Gene networks and expression quantitative trait loci associated with adjuvant chemotherapy response in high-grade serous ovarian cancer

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Jihoon Choi, Danai G. Topouza, Anastasiya Tarnouskaya, Sean Nesdoly, Madhuri Koti, Qing Ling Duan

Role of the initial degree of anaemia and treatment model in the prognosis of gastric cancer patients treated by chemotherapy: a retrospective analysis

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Wen-Huan Li, Ji-Yu Zhang, Wen-Hui Liu, Xian-Xian Chen

Rehabilitation strategies following oesophagogastric and Hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomized controlled trial

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Linda O’Neill, Emer Guinan, Suzanne Doyle, Deirdre Connolly, Jacintha O’Sullivan, Annemarie Bennett, Grainne Sheill, Ricardo Segurado, Peter Knapp, Ciaran Fairman, Charles Normand, Justin Geoghegan, Kevin Conlon, John V. Reynolds, Juliette Hussey

Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab

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Hangyu Zhang, Liyun Yuan, Lulu Liu, Cong Yan, Jinming Cheng, Qihan Fu, Zhou Tong, Weiqin Jiang, Yi Zheng, Peng Zhao, Guoqing Zhang, Weijia Fang

Novel methods for in vitro modeling of pancreatic cancer reveal important aspects for successful primary cell culture

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L. Ehlen, J. Arndt, D. Treue, P. Bischoff, F. N. Loch, E. M. Hahn, K. Kotsch, F. Klauschen, K. Beyer, G. A. Margonis, M. E. Kreis, C. Kamphues

Combined endocrine approaches vs endocrine therapy alone as first line treatment in elderly patients with hormone receptor-positive, HER2 negative, advanced breast cancer: to prescribe for the patient or the physician? A meta-analysis of phase II and III randomized clinical trials

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Claudia Omarini, Federico Piacentini, Isabella Sperduti, Monica Barbolini, Chrystel Isca, Angela Toss, Laura Cortesi, Elena Barbieri, Massimo Dominici, Luca Moscetti

Targeted imaging of orthotopic prostate cancer by using clinical transformable photoacoustic molecular probe

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Chen Qiu, Yuanyuan Bai, Tinghui Yin, Xiaoyan Miao, Rongkang Gao, Huichao Zhou, Jie Ren, Liang Song, Chengbo Liu, Hairong Zheng, Rongqin Zheng

Prognostic implication and functional exploration for microRNA-20a as a molecular biomarker of gastrointestinal cancer

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Qiliang Peng, Peifeng Zhao, Yi Shen, Ming Cheng, Yongyou Wu, Yaqun Zhu

Disease-free survival as a surrogate endpoint for overall survival in adjuvant trials of pancreatic cancer: a meta-analysis of 20 randomized controlled trials

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Run-Cong Nie, Xue-Bin Zou, Shu-Qiang Yuan, Ying-Bo Chen, Shi Chen, Yong-Ming Chen, Guo-Ming Chen, Xiao-Jiang Chen, Tian-Qi Luo, Shu-Man Li, Jin-Ling Duan, Yun Wang, Yuan-Fang Li

Prognostic and predictive factors for Taiwanese patients with advanced biliary tract cancer undergoing frontline chemotherapy with gemcitabine and cisplatin: a real-world experience

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Chiao-En Wu, Wen-Chi Chou, Chia-Hsun Hsieh, John Wen-Cheng Chang, Cheng-Yu Lin, Chun-Nan Yeh, Jen-Shi Chen

Clinical value of serum squamous cell carcinoma antigen levels in predicting chemosensitivity, lymph node metastasis, and prognosis in patients with cervical squamous cell carcinoma

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Peng Chen, Liang Jiao, Fang Ren, Dan-Bo Wang

Podoplanin is a useful prognostic marker and indicates better differentiation in lung squamous cell cancer patients? A systematic review and meta-analysis

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Liya Hu, Peng Zhang, Qi Mei, Wei Sun, Lei Zhou, Tiejun Yin

PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer

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Lutfi H. Alfarsi, Rokaya El Ansari, Madeleine L. Craze, Brendah K. Masisi, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

CDX2 expression and perioperative patient serum affects the adhesion properties of cultured colon cancer cells

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Johanne Davidsen, Stine Bull Jessen, Sara Kehlet Watt, Sylvester Larsen, Katja Dahlgaard, Tove Kirkegaard, Ismail Gögenur, Jesper T. Troelsen

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model

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Chidimma Agatha Akpa, Karsten Kleo, Elisabeth Oker, Nancy Tomaszewski, Clemens Messerschmidt, Cristina López, Rabea Wagener, Kathrin Oehl-Huber, Katja Dettmer, Anne Schoeler, Dido Lenze, Peter J. Oefner, Dieter Beule, Reiner Siebert, David Capper, Lora Dimitrova, Michael Hummel

Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells

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Christine Moore, Victoria E. Palau, Rashid Mahboob, Janet Lightner, William Stone, Koyamangalath Krishnan

A competing risk nomogram predicting cause-specific mortality in patients with lung adenosquamous carcinoma

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Xiao Wu, Wenfeng Yu, R. H. Petersen, Hongxu Sheng, Yiqing Wang, Wang Lv, Jian Hu

Quantitative hormone receptor (HR) expression and gene expression analysis in HR+ inflammatory breast cancer (IBC) vs non-IBC

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Toshiaki Iwase, Kenichi Harano, Hiroko Masuda, Kumiko Kida, Kenneth R. Hess, Ying Wang, Luc Dirix, Steven J. Van Laere, Anthony Lucci, Savitri Krishnamurthy, Wendy A. Woodward, Rachel M. Layman, François Bertucci, Naoto T. Ueno

The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

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Mark de Mol, Sabine Visser, Joachim Aerts, Paul Lodder, Nico van Walree, Huub Belderbos, Brenda den Oudsten

Prevalence and correlates of job and insurance problems among young breast cancer survivors within 18 months of diagnosis

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Michelle J. Naughton, Chloe M. Beverly Hery, Sarah A. Janse, Elizabeth Z. Naftalis, Electra D. Paskett, Kimberly J. Van Zee

The combination of methotrexate and cytosine arabinoside in newly diagnosed adult Langerhans cell histiocytosis: a prospective phase II interventional clinical trial

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Xiao Han, Mingqi Ouyang, Minghui Duan, Wei Zhang, Tienan Zhu, Jian Li, Shujie Wang, Daobin Zhou

Roles of DANCR/microRNA-518a-3p/MDMA ceRNA network in the growth and malignant behaviors of colon cancer cells

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Yi Sun, Bin Cao, Jingzhen Zhou

Different regulation of PARP1, PARP2, PARP3 and TRPM2 genes expression in acute myeloid leukemia cells

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Paulina Gil-Kulik, Ewa Dudzińska, Elżbieta Radzikowska-Büchner, Joanna Wawer, Mariusz Jojczuk, Adam Nogalski, Genowefa Anna Wawer, Marcin Feldo, Wojciech Kocki, Maria Cioch, Anna Bogucka-Kocka, Mansur Rahnama, Janusz Kocki

DPD status and fluoropyrimidines-based treatment: high activity matters too

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Emmanuel Chamorey, Eric Francois, Marie-Christine Etienne, Jean-Marc Ferrero, Frederic Peyrade, Emmanuel Barranger, Alexandre Bozec, Rémy Largillier, Ophelie Cassuto, Julien Viotti, Renaud Schiappa, Gérard Milano

Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status

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Ilona Dudka, Elin Thysell, Kristina Lundquist, Henrik Antti, Diego Iglesias-Gato, Amilcar Flores-Morales, Anders Bergh, Pernilla Wikström, Gerhard Gröbner

Physical activity and long-term fatigue among colorectal cancer survivors – a population-based prospective study

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Ruth Elisa Eyl, Melissa S. Y. Thong, Prudence R. Carr, Lina Jansen, Lena Koch-Gallenkamp, Michael Hoffmeister, Jenny Chang-Claude, Hermann Brenner, Volker Arndt

Prognostic model based on the geriatric nutritional risk index and sarcopenia in patients with diffuse large B-cell lymphoma

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Se-Il Go, Hoon-Gu Kim, Myoung Hee Kang, Sungwoo Park, Gyeong-Won Lee

Early prediction of pathologic response to neoadjuvant treatment of breast cancer: use of a cell-loss metric based on serum thymidine kinase 1 and tumour volume

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Bernhard Tribukait

Preoperative SCC-Ag as a predictive marker for the use of adjuvant chemotherapy in cervical squamous cell carcinoma with intermediate-risk factors

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Hong-tao Guo, Xue-han Bi, Ting Lei, Xiao Lv, Guang Yao, Yao Chen, Chang Liu

Stereotactic body radiotherapy (SBRT) in patients with lung metastases - prognostic factors and long-term survival using patient self-reported outcome (PRO)

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Kerstin A. Kessel, Rebekka C. E. Grosser, Kim Melanie Kraus, Hans Hoffmann, Markus Oechsner, Stephanie E. Combs

The role of human papillomavirus genotyping for detecting high-grade intraepithelial neoplasia or cancer in HPV-positive women with normal cytology: a study from a hospital in northeastern China

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Jing Zhang, Deyu Zhang, Zhuo Yang, Xiaobin Wang, Danbo Wang

Multiple HPV 16 infection with two strains: a possible marker of neoplastic progression

• Open Access
• Research article

Maria Teresa Bruno, Guido Scalia, Nazario Cassaro, Sara Boemi

Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer

• Open Access
• Research article

Robert Wesolowski, Andrew Stiff, Dionisia Quiroga, Christopher McQuinn, Zaibo Li, Hiroaki Nitta, Himanshu Savardekar, Brooke Benner, Bhuvaneswari Ramaswamy, Maryam Lustberg, Rachel M. Layman, Erin Macrae, Mahmoud Kassem, Nicole Williams, Sagar Sardesai, Jeffrey VanDeusen, Daniel Stover, Mathew Cherian, Thomas A. Mace, Lianbo Yu, Megan Duggan, William E. Carson III

Comparison of hybrid clones derived from human breast epithelial cells and three different cancer cell lines regarding in vitro cancer stem/ initiating cell properties

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Sera Selina Fahlbusch, Silvia Keil, Jörg T. Epplen, Kurt S. Zänker, Thomas Dittmar

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients

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• Research article

Paula Whitmire, Cassandra R. Rickertsen, Andrea Hawkins-Daarud, Eduardo Carrasco Jr, Julia Lorence, Gustavo De Leon, Lee Curtin, Spencer Bayless, Kamala Clark-Swanson, Noah C. Peeri, Christina Corpuz, Christine Paula Lewis-de los Angeles, Bernard R. Bendok, Luis Gonzalez-Cuyar, Sujay Vora, Maciej M. Mrugala, Leland S. Hu, Lei Wang, Alyx Porter, Priya Kumthekar, Sandra K. Johnston, Kathleen M. Egan, Robert Gatenby, Peter Canoll, Joshua B. Rubin, Kristin R. Swanson

Prognostic and diagnostic value of circRNA expression in colorectal carcinoma: a meta-analysis

• Open Access
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Jinpeng Yuan, Dongming Guo, Xinxin Li, Juntian Chen

Modified FOLFIRINOX as a second-line therapy following gemcitabine plus nab-paclitaxel therapy in metastatic pancreatic cancer

• Open Access
• Research article

Masashi Sawada, Akiyoshi Kasuga, Takafumi Mie, Takaaki Furukawa, Takanobu Taniguchi, Koshiro Fukuda, Yuto Yamada, Tsuyoshi Takeda, Ryo Kanata, Masato Matsuyama, Takashi Sasaki, Masato Ozaka, Naoki Sasahira

The clinical significance of the T2-FLAIR mismatch sign in grade II and III gliomas: a population-based study

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Alba Corell, Sandra Ferreyra Vega, Nickoleta Hoefling, Louise Carstam, Anja Smits, Thomas Olsson Bontell, Isabella M. Björkman-Burtscher, Helena Carén, Asgeir Store Jakola

Association of surgical margins with local recurrence in patients undergoing breast-conserving surgery after neoadjuvant chemotherapy

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Joseph Lin, Kuo-Juei Lin, Yu-Fen Wang, Ling-Hui Huang, Sam Li-Sheng Chen, Dar-Ren Chen

The introduction of risk stratified screening into the NHS breast screening Programme: views from British-Pakistani women

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• Research article

Victoria G. Woof, Helen Ruane, David P. French, Fiona Ulph, Nadeem Qureshi, Nasaim Khan, D. Gareth Evans, Louise S. Donnelly

Incidence of subsequent primary cancers and radiation-induced subsequent primary cancers after low dose-rate brachytherapy monotherapy for prostate cancer in long-term follow-up

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Kristiina Vuolukka, Päivi Auvinen, Jan-Erik Palmgren, Sirpa Aaltomaa, Vesa Kataja

Tumor-associated tissue eosinophilia predicts favorable clinical outcome in solid tumors: a meta-analysis

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Guoming Hu, Shimin Wang, Kefang Zhong, Feng Xu, Liming Huang, Wei Chen, Pu Cheng

Insight into bladder cancer care: study protocol of a large nationwide prospective cohort study (BlaZIB)

• Open Access
• Study protocol

T. M. Ripping, L. A. Kiemeney, L. M. C. van Hoogstraten, J. A. Witjes, K. K. H. Aben, Joost Boormans, Theo de Reijke, Catharina A. Goossens, Sipke Helder, Maarten C. C. M. Hulshof, Geert J. L. H. van Leenders, Annemarie M. van Leliveld, Richard P. Meijer, Sasja Mulder, Ronald I. Nooter, Juus L. Noteboom, Jorg R. Oddens, Tineke J. Smilde, Guus W. J. Vanderbosch, Antoine G. van der Heijden, Michiel S. van der Heijden, Reindert J. A. van Moorselaar, Bas W. G. van Rhijn, Joep G. H. van Roermund, Bart P. Wijsman

A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma

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Guangzhi Wu, Minglei Zhang

Metastasis-directed therapy in castration-refractory prostate cancer (MEDCARE): a non-randomized phase 2 trial

• Open Access
• Study protocol

Charlien Berghen, Steven Joniau, Kato Rans, Gaëtan Devos, Kenneth Poels, Koen Slabbaert, Herlinde Dumez, Maarten Albersen, Karolien Goffin, Karin Haustermans, Gert De Meerleer

Experiences and views of different key stakeholders on the feasibility of treating cancer-related fatigue

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Claudia Canella, Michael Mikolasek, Matthias Rostock, Matthias Guckenberger, Josef Jenewein, Esther Linka, Claudia Six, Sarah Stoll, Roger Stupp, Claudia M. Witt

LRIG1 gene copy number analysis by ddPCR and correlations to clinical factors in breast cancer

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Mahmood Faraz, Andreas Tellström, Christina Edwinsdotter Ardnor, Kjell Grankvist, Lukasz Huminiecki, Björn Tavelin, Roger Henriksson, Håkan Hedman, Ingrid Ljuslinder

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study

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Karolin Bucksch, Silke Zachariae, Stefan Aretz, Reinhard Büttner, Elke Holinski-Feder, Stefanie Holzapfel, Robert Hüneburg, Matthias Kloor, Magnus von Knebel Doeberitz, Monika Morak, Gabriela Möslein, Jacob Nattermann, Claudia Perne, Nils Rahner, Wolff Schmiegel, Karsten Schulmann, Verena Steinke-Lange, Christian P. Strassburg, Deepak B. Vangala, Jürgen Weitz, Markus Loeffler, Christoph Engel

Could venous thromboembolism and major bleeding be indicators of lung cancer mortality? A nationwide database study

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Jennifer Howlett, Eric Benzenine, Jonathan Cottenet, Pascal Foucher, Philippe Fagnoni, Catherine Quantin

Text mining in a literature review of urothelial cancer using topic model

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Hsuan-Jen Lin, Phillip C.-Y. Sheu, Jeffrey J. P. Tsai, Charles C. N. Wang, Che-Yi Chou

Comparison of 99mTc-MIBI scintigraphy, ultrasound, and mammography for the diagnosis of BI-RADS 4 category lesions

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Hongbiao Liu, Hongwei Zhan, Da Sun

Combination of preoperative neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio: a superior prognostic factor of endometrial cancer

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Rong Cong, Fanfei Kong, Jian Ma, Qing Li, Qijun Wu, Xiaoxin Ma

Association of Helicobacter pylori babA2 gene and gastric cancer risk: a meta-analysis

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Marce-Amara Kpoghomou, Jinchen Wang, Tianpei Wang, Guanfu Jin

Achieving objective response in treatment of non-resectable neuroendocrine tumors does not predict longer time to progression compared to achieving stable disease

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Espen Thiis-Evensen, Amalie Christine Poole, Hong-Thien Thi Nguyen, Jon Sponheim

Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer

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Hideaki Tsuyoshi, Makoto Orisaka, Yuko Fujita, Meshach Asare-Werehene, Benjamin K. Tsang, Yoshio Yoshida

CT-based radiomics scores predict response to neoadjuvant chemotherapy and survival in patients with gastric cancer

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Kai-Yu Sun, Hang-Tong Hu, Shu-Ling Chen, Jin-Ning Ye, Guang-Hua Li, Li-Da Chen, Jian-Jun Peng, Shi-Ting Feng, Yu-Jie Yuan, Xun Hou, Hui Wu, Xin Li, Ting-Fan Wu, Wei Wang, Jian-Bo Xu

Independence of HIF1a and androgen signaling pathways in prostate cancer

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Maxine G. B. Tran, Becky A. S. Bibby, Lingjian Yang, Franklin Lo, Anne Y. Warren, Deepa Shukla, Michelle Osborne, James Hadfield, Thomas Carroll, Rory Stark, Helen Scott, Antonio Ramos-Montoya, Charlie Massie, Patrick Maxwell, Catharine M. L. West, Ian G. Mills, David E. Neal

Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer

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Dean C. Singleton, Anne-Lise Dechaume, Pamela M. Murray, William P. Katt, Bruce C. Baguley, Euphemia Y. Leung

The prognostic value of IDO expression in solid tumors: a systematic review and meta-analysis

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Sen Wang, Jia Wu, Han Shen, Junjun Wang

Hyperfunction of CD4 CD25 regulatory T cells in de novo acute myeloid leukemia

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Yuling Wan, Congxiao Zhang, Yingxi Xu, Min Wang, Qing Rao, Haiyan Xing, Zheng Tian, Kejing Tang, Yingchang Mi, Ying Wang, Jianxiang Wang

Elderly women’s experiences of self-sampling for HPV testing

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Ruth S. Hermansson, Matts Olovsson, Catharina Gustavsson, Annika Kristina Lindström

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

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José Ignácio Gonzalez Solari, Eduardo Filippi-Chiela, Emily Salles Pilar, Vitória Nunes, Esteban Alberto Gonzalez, Fabrício Figueiró, Cristiano Feijó Andrade, Fábio Klamt

A novel pancreatic tumour and stellate cell 3D co-culture spheroid model

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K. J. Norberg, X. Liu, C. Fernández Moro, C. Strell, S. Nania, M. Blümel, A. Balboni, B. Bozóky, R. L. Heuchel, J. M. Löhr

Cancer staging in individuals with a severe psychiatric illness: a cross-sectional study using population-based cancer registry data

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Alyson L. Mahar, Paul Kurdyak, Timothy P. Hanna, Natalie G. Coburn, Patti A. Groome

Knowledge, attitudes and practices of South Asian immigrants in developed countries regarding oral cancer: an integrative review

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Nidhi Saraswat, Rona Pillay, Bronwyn Everett, Ajesh George

An isolated vaginal metastasis from intestinal signet ring cell carcinoma: a case report and literature review

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• Case report

Xiao Dan Zhu, Jin Wang, Qin Han You, Tian An Jiang

Frequency of anaplastic lymphoma kinase rearrangements in Moroccan patients with non small cell lung cancer: a multi-institutional national retrospective study

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Hind El yacoubi, Mohamed Lemine Sow, Fouad Kettani, Lamia Gamra, Amina Mestari, Lamia Jabri, Ibrahim Elghissassi, Hassan Errihani

CYP19A1 gene expression in the peripheral blood of Brazilian women with breast cancer relapse

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Maria da Conceição Barros-Oliveira, Danylo Rafhael Costa-Silva, Larysse Cardoso Campos-Verdes, Renato de Oliveira Pereira, Rozirene Araújo Silva, Paulo de Tarso Moura-Borges, Emerson Brandão Sousa, André Luiz Pinho-Sobral, Pedro Vitor Lopes-Costa, Alesse Ribeiro dos Santos, Ione Maria Ribeiro Soares-Lopes, Jackeline Lopes Viana, Mariella de Almeida Melo, Fidelis Manes Neto, Eid Gonçalves Coelho, Maria do Socorro Pires e Cruz, Vladimir Costa-Silva, Luiz Henrique Gebrim, Benedito Borges Da Silva

The structural effect of high intensity ultrasound on peritoneal tissue: a potential vehicle for targeting peritoneal metastases

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Agata Mikolajczyk, Tanja Khosrawipour, Joanna Kulas, Pawel Migdal, Mohamed Arafkas, Jakub Nicpon, Veria Khosrawipour

Discrimination between clinical significant and insignificant prostate cancer with apparent diffusion coefficient – a systematic review and meta analysis

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Hans-Jonas Meyer, Andreas Wienke, Alexey Surov

Prognostic role of alpha-fetoprotein in patients with hepatocellular carcinoma treated with repeat transarterial chemoembolisation

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Gauri Mishra, Anouk Dev, Eldho Paul, Wa Cheung, Jim Koukounaras, Ashu Jhamb, Ben Marginson, Beng Ghee Lim, Paul Simkin, Adina Borsaru, James Burnes, Mark Goodwin, Vivek Ramachandra, Manfred Spanger, John Lubel, Paul Gow, Siddharth Sood, Alexander Thompson, Marno Ryan, Amanda Nicoll, Sally Bell, Ammar Majeed, William Kemp, Stuart K. Roberts

Systematic screening as a tool for individualized rehabilitation following primary breast cancer treatment: study protocol for the ReScreen randomized controlled trial

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• Study protocol

U. Olsson Möller, L. Rydén, M. Malmström

NORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial)

• Open Access
• Study protocol

Antoine Brouquet, Jean-Baptiste Bachet, Florence Huguet, Mehdi Karoui, Pascal Artru, Charles Sabbagh, Jérémie H. Lefèvre, Dewi Vernerey, Christophe Mariette, Eric Vicaut, Stephane Benoist

A scientometric analysis of neuroblastoma research

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Illya Martynov, Jessica Klima-Frysch, Joachim Schoenberger

Perioperative blood transfusion has distinct postsurgical oncologic impact on patients with different stage of hepatocellular carcinoma

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Gui-Xing Chen, Chao-Ying Qi, Wen-Jie Hu, Xiao-Hui Wang, Yun-Peng Hua, Ming Kuang, Bao-Gang Peng, Shao-Qiang Li

Patient and tumour characteristics associated with inclusion in Cancer patient pathways in Norway in 2015–2016

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Yngvar Nilssen, Odd Terje Brustugun, Morten Tandberg Eriksen, Erik Skaaheim Haug, Bjørn Naume, Bjørn Møller

Components of metabolic syndrome in patients with multiple myeloma and smoldering multiple myeloma

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Efrat Markus, Svetlana Trestman, Yael Cohen, Yoel Angel, Yael Sofer, Moshe Mittelman, Irit Avivi, Naftali Stern, Elena Izkhakov

SCDb: an integrated database of stomach cancer

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• Database

Erli Gu, Wei Song, Ajing Liu, Hong Wang

Histologic subtyping affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis

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Francesca Sanges, Matteo Floris, Paolo Cossu-Rocca, Maria R. Muroni, Giovanna Pira, Silvana Anna Maria Urru, Renata Barrocu, Silvano Gallus, Cristina Bosetti, Maurizio D’Incalci, Alessandra Manca, Maria Gabriela Uras, Ricardo Medda, Elisabetta Sollai, Alma Murgia, Dolores Palmas, Francesco Atzori, Angelo Zinellu, Francesca Cambosu, Tiziana Moi, Massimo Ghiani, Vincenzo Marras, Maria Cristina Santona, Luisa Canu, Enrichetta Valle, Maria Giuseppina Sarobba, Daniela Onnis, Anna Asunis, Sergio Cossu, Sandra Orrù, Maria Rosaria De Miglio

A phase II randomized trial of RAdium-223 dichloride and SABR Versus SABR for oligomEtastatic prostate caNcerS (RAVENS)

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• Study protocol

Hamza Hasan, Matthew P. Deek, Ryan Phillips, Robert F. Hobbs, Reem Malek, Noura Radwan, Ana P. Kiess, Shirl Dipasquale, James Huang, Terry Caldwell, Jessica Leitzel, Danielle Wendler, Hao Wang, Elizabeth Thompson, Jonathan Powell, Sara Dudley, Curtiland Deville, Stephen C. Greco, Daniel Y. Song, Theodore L. DeWeese, Michael A. Gorin, Steven P. Rowe, Sam Denmeade, Mark Markowski, Emmanuel S. Antonarakis, Michael A. Carducci, Mario A. Eisenberger, Martin G. Pomper, Kenneth J. Pienta, Channing J. Paller, Phuoc T. Tran

Association between Epstein-Barr virus infection and gastric cancer: a systematic review and meta-analysis

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Ahmad Tavakoli, Seyed Hamidreza Monavari, Farid Solaymani Mohammadi, Seyed Jalal Kiani, Saber Armat, Mohammad Farahmand

Diagnostic and prognostic nomograms for bone metastasis in hepatocellular carcinoma

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Chuan Hu, Jiaxin Yang, Zhangheng Huang, Chuan Liu, Yijun Lin, Yuexin Tong, Zhiyi Fan, Bo Chen, Cailin Wang, Cheng-Liang Zhao

Improving communication between the general practitioner and the oncologist: a key role in coordinating care for patients suffering from cancer

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Vladimir Druel, Laetitia Gimenez, Kim Paricaud, Jean-Pierre Delord, Pascale Grosclaude, Nathalie Boussier, Marie-Eve Rougé Bugat

Augmenting cancer registry data with health survey data with no cases in common: the relationship between pre-diagnosis health behaviour and post-diagnosis survival in oesophageal cancer

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Paul P. Fahey, Andrew Page, Glenn Stone, Thomas Astell-Burt

MassARRAY analysis of twelve cancer related SNPs in esophageal squamous cell carcinoma in J&K, India

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Ruchi Shah, Varun Sharma, Amrita Bhat, Hemender Singh, Indu Sharma, Sonali Verma, Gh. Rasool Bhat, Bhanu Sharma, Divya Bakshi, Rakesh Kumar, Nazir Ahmed Dar

Optimize the dose of oxaliplatin for locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy followed by radical surgery and adjuvant chemotherapy

• Open Access
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Hui Chang, Ya-lan Tao, Wu Jiang, Chen Chen, Shi-liang Liu, Wei-jun Ye, Yuan-hong Gao

Performance of ultrasonography screening for breast cancer: a systematic review and meta-analysis

• Open Access
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Lei Yang, Shengfeng Wang, Liwen Zhang, Chao Sheng, Fengju Song, Ping Wang, Yubei Huang

Craniospinal irradiation(CSI) in patients with leptomeningeal metastases: risk-benefit-profile and development of a prognostic score for decision making in the palliative setting

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Michal Devecka, Marciana Nona Duma, Jan J. Wilkens, Severin Kampfer, Kai Joachim Borm, Stefan Münch, Christoph Straube, Stephanie E. Combs

The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

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Matthew P. Humphries, Stephanie G. Craig, Rafal Kacprzyk, Natalie C. Fisher, Victoria Bingham, Stephen McQuaid, Graeme I. Murray, Damian McManus, Richard C. Turkington, Jacqueline James, Manuel Salto-Tellez

A differential risk assessment and decision model for Transarterial chemoembolization in hepatocellular carcinoma based on hepatic function

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Joon Yeul Nam, A Reum Choe, Dong Hyun Sinn, Jeong-Hoon Lee, Hwi Young Kim, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Jeong Min Lee, Jin Wook Chung, Sun Young Choi, Jeong Kyong Lee, Seung Yon Baek, Hye Ah Lee, Tae Hun Kim, Kwon Yoo

A convenient clinical nomogram for predicting the cancer-specific survival of individual patients with small-intestine adenocarcinoma

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Na Wang, Jin Yang, Jun Lyu, Qingqing Liu, Hairong He, Jie Liu, Li Li, Xuequn Ren, Zhendong Li

Machine-learning based MRI radiomics models for early detection of radiation-induced brain injury in nasopharyngeal carcinoma

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Bin Zhang, Zhouyang Lian, Liming Zhong, Xiao Zhang, Yuhao Dong, Qiuying Chen, Lu Zhang, Xiaokai Mo, Wenhui Huang, Wei Yang, Shuixing Zhang

Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217)

• Open Access
• Study protocol

Joseph Tintelnot, Eray Goekkurt, Mascha Binder, Peter Thuss-Patience, Sylvie Lorenzen, Jorge Riera Knorrenschild, Albrecht Kretzschmar, Thomas Ettrich, Udo Lindig, Lutz Jacobasch, Daniel Pink, Salah-Eddin Al-Batran, Axel Hinke, Susanna Hegewisch-Becker, Sven Nilsson, Carsten Bokemeyer, Alexander Stein

Biomarker roles identification of miR-106 family for predicting the risk and poor survival of colorectal cancer

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Qiliang Peng, Yi Shen, Peifeng Zhao, Ming Cheng, Yaqun Zhu, Bo Xu

Similar response rates and survival with PARP inhibitors for patients with solid tumors harboring somatic versus Germline BRCA mutations: a Meta-analysis and systematic review

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Ghulam Rehman Mohyuddin, Muhammad Aziz, Alec Britt, Lee Wade, Weijing Sun, Joaquina Baranda, Raed Al-Rajabi, Anwaar Saeed, Anup Kasi

Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study

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A. E. Howell, J. W. Robinson, R. E. Wootton, A. McAleenan, S. Tsavachidis, Q. T. Ostrom, M. Bondy, G. Armstrong, C. Relton, P. Haycock, R. M. Martin, J. Zheng, K. M. Kurian

Total DNA methylation as a biomarker of DNA damage and tumor malignancy in intracranial meningiomas

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Anna-Maria Barciszewska

Effect of aspirin on PET parameters in primary non-small cell lung cancer and its relationship with prognosis

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Jinghua Chen, Junxian Xia, Jiacheng Huang, Ruilian Xu

Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma

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Joon Won Yoon, Marilyn Lamm, Christopher Chandler, Philip Iannaccone, David Walterhouse

Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models

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Rayna Rosati, Kailey Oppat, Yanfang Huang, Seongho Kim, Manohar Ratnam

Factors predictive of invasive ductal carcinoma in cases preoperatively diagnosed as ductal carcinoma in situ

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Koji Takada, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Tamami Morisaki, Katsuyuki Takahashi, Hisakazu Fujita, Tsutomu Takashima, Shuhei Tomita, Kosei Hirakawa, Masaichi Ohira

Preoperative clinical characteristics scoring system for differentiating uterine leiomyosarcoma from fibroid

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Guorui Zhang, Xin Yu, Lan Zhu, Qingbo Fan, Honghui Shi, Jinghe Lang

A retrospective study of patient-tailored FOLFIRINOX as a first-line chemotherapy for patients with advanced biliary tract cancer

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Ayhan Ulusakarya, Abdoulaye Karaboué, Oriana Ciacio, Gabriella Pittau, Mazen Haydar, Pamela Biondani, Yusuf Gumus, Amale Chebib, Wathek Almohamad, Pasquale F. Innominato

The molecular pathogenesis of Trichilemmal carcinoma

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Jeong Hyun Ha, Cheol Lee, Kyu Sang Lee, Chang-sik Pak, Choong-Hyun Sun, Youngil Koh, Hak Chang

Clinical significance of prognostic inflammation-based and/or nutritional markers in patients with stage III gastric cancer

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Takahiro Toyokawa, Kazuya Muguruma, Mami Yoshii, Tatsuro Tamura, Katsunobu Sakurai, Naoshi Kubo, Hiroaki Tanaka, Shigeru Lee, Masakazu Yashiro, Masaichi Ohira

Optimal cumulative dose of cisplatin for concurrent chemoradiotherapy among patients with non-metastatic nasopharyngeal carcinoma: a multicenter analysis in Thailand

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Nuttapong Ngamphaiboon, Arunee Dechaphunkul, Jiraporn Setakornnukul, Tanadech Dechaphunkul, Rungarun Jiratrachu, Bhoom Suktitipat, Chuleeporn Jiarpinitnun, Poompis Pattaranutaporn, Pongwut Danchaivijitr

Prostate-specific membrane antigen (PSMA) expression in adenoid cystic carcinoma of the head and neck

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Thomas J. W. Klein Nulent, Matthijs H. Valstar, Laura A. Smit, Ludwig E. Smeele, Nicolaas P. A. Zuithoff, Bart de Keizer, Remco de Bree, Robert J. J. van Es, Stefan M. Willems

Adenocarcinomatous-predominant subtype associated with a better prognosis in adenosquamous lung carcinoma

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Yangli Liu, Ying Zhu, Lihong Bai, Fengjia Chen, Jue Wang, Yubiao Guo

Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma

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Seijiro Koshimune, Mitsuko Kosaka, Nobuhiko Mizuno, Hiromasa Yamamoto, Tomoyuki Miyamoto, Kohta Ebisui, Shinichi Toyooka, Aiji Ohtsuka

RETRACTED ARTICLE: miR-874 inhibits gastric cancer cell proliferation by targeting SPAG9

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Qin Hui Sun, Zong Xiu Yin, Zhi Li, Shu Bo Tian, Hong Chang Wang, Fang Xu Zhang, Le Ping Li, Chun Ning Zheng, Shuai Kong

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

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• Study protocol

Cornelis M. van Tilburg, Ruth Witt, Melanie Heiss, Kristian W. Pajtler, Christoph Plass, Isabel Poschke, Michael Platten, Inga Harting, Oliver Sedlaczek, Angelika Freitag, David Meyrath, Lenka Taylor, Gnana Prakash Balasubramanian, Natalie Jäger, Elke Pfaff, Barbara C. Jones, Till Milde, Stefan M. Pfister, David T. W. Jones, Annette Kopp-Schneider, Olaf Witt

The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments

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Bertin Hoffmann, Tobias Lange, Vera Labitzky, Kristoffer Riecken, Andreas Wree, Udo Schumacher, Gero Wedemann

Expression of tripartite motif-containing 44 and its prognostic and clinicopathological value in human malignancies:a meta-analysis

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Guoliang Xiao, Qiuxi Yang, Ziwei Bao, Haixia Mao, Yi Zhang, Shibu Lin

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

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Katerina Hlozkova, Alena Pecinova, Natividad Alquezar-Artieda, David Pajuelo-Reguera, Marketa Simcikova, Lenka Hovorkova, Katerina Rejlova, Marketa Zaliova, Tomas Mracek, Alexandra Kolenova, Jan Stary, Jan Trka, Julia Starkova

Activity of PD1 inhibitor therapy in advanced sarcoma: a single-center retrospective analysis

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Dionisia Quiroga, David A. Liebner, Jennifer S. Philippon, Sarah Hoffman, Yubo Tan, James L. Chen, Scott Lenobel, Paul E. Wakely Jr, Raphael Pollock, Gabriel Tinoco

Meeting psychosocial needs to improve health: a prospective cohort study

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Austyn Snowden, Jenny Young, Jan Savinc

The patient-level effect of the cost of Cancer care – financial burden in German Cancer patients

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Katja Mehlis, Julian Witte, Bastian Surmann, Matthias Kudlich, Leonidas Apostolidis, Jürgen Walther, Dirk Jäger, Wolfgang Greiner, Eva C. Winkler

A novel nomogram to predict the reliability of estimated glomerular filtration rate formulae in oncology patients

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Yichun Cheng, Liu Huang, Yunfeng Han, Chummun Vanisha, Shuwang Ge, Gang Xu

R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers

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Tomer Boldes, Keren Merenbakh-Lamin, Shani Journo, Eliya Shachar, Doron Lipson, Adva Yeheskel, Metsada Pasmanik-Chor, Tami Rubinek, Ido Wolf

Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) – a phase II prospective randomized multicenter trial (NOA-14, ARO 2015–3, DKTK-ROG)

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• Study protocol

Anca-Ligia Grosu, Lars Frings, Iryna Bentsalo, Oliver Oehlke, Franziska Brenner, Angelika Bilger, Jamina Tara Fennell, Thomas Rothe, Sabine Schneider-Fuchs, Erika Graf, Claudia Schmoor, Jürgen Beck, Gerhild Becker, Michael Bock, Karl Egger, Horst Urbach, Claas Lahmann, Ilinca Popp

The development and validation of a radiomic nomogram for the preoperative prediction of lung adenocarcinoma

• Open Access
• Research article

Qin Liu, Yan Huang, Huai Chen, Yanwen Liu, Ruihong Liang, Qingsi Zeng

A prognostic nomogram for the cancer-specific survival of patients with upper-tract urothelial carcinoma based on the Surveillance, Epidemiology, and End Results Database

• Open Access
• Research article

Chengzhuo Li, Jin Yang, Fengshuo Xu, Didi Han, Shuai Zheng, Rahel Elishilia Kaaya, Shengpeng Wang, Jun Lyu

Immunohistochemical expression of vitamin D receptor and forkhead box P3 in classic Hodgkin lymphoma: correlation with clinical and pathologic findings

• Open Access
• Research article

Gaurav K. Gupta, Tanupriya Agrawal, Monika Pilichowska

Single-institutional outcome-analysis of low-dose stereotactic body radiation therapy (SBRT) of adrenal gland metastases

• Open Access
• Research article

Theresa Voglhuber, Kerstin A. Kessel, Markus Oechsner, Marco M. E. Vogel, Jürgen E. Gschwend, Stephanie E. Combs

Elective neck dissection versus wait-and-see policy in cT1N0 buccal squamous cell carcinoma

• Open Access
• Research article

Qigen Fang, Hua Gao, Qing Gao, Jinlan Sun, Peng Li, Meng Cui, Enxi Zhang, Wenlong Yin, Yuanyuan Dong

The impact of neoadjuvant and adjuvant immunotherapy on the survival of pancreatic cancer patients: a retrospective analysis

• Open Access
• Research article

Saber Amin, Michael Baine, Jane Meza, Chi Lin

Adjuvant VACcination against HPV in surgical treatment of Cervical Intra-epithelial Neoplasia (VACCIN study) a study protocol for a randomised controlled trial

• Open Access
• Study protocol

R. L. O. van de Laar, W. Hofhuis, R. G. Duijnhoven, S. Polinder, W. J. G. Melchers, F. J. van Kemenade, R. L. M. Bekkers, H. J. Van Beekhuizen

Role of high-dose salvage radiotherapy for oligometastases of the localised abdominal/pelvic lymph nodes: a retrospective study

• Open Access
• Research article

Makoto Ito, Takeshi Kodaira, Yutaro Koide, Takahito Okuda, Shinichiro Mizumatsu, Yukihiko Oshima, Arisa Takeuchi, Toshie Mori, Souichirou Abe, Ayumi Asai, Kojiro Suzuki

Albumin-to-alkaline phosphatase ratio serves as a prognostic indicator in unresectable pancreatic ductal adenocarcinoma: a propensity score matching analysis

• Open Access
• Research article

Ke Zhang, Shu Dong, Yan-Hua Jing, Hui-Feng Gao, Lian-Yu Chen, Yong-Qiang Hua, Hao Chen, Zhen Chen

LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target

• Open Access
• Research article

Catharina Hagerling, Mark Owyong, Vaishnavi Sitarama, Chih-Yang Wang, Charlene Lin, Renske J. E. van den Bijgaart, Charlotte D. Koopman, Audrey Brenot, Ankitha Nanjaraj, Fredrik Wärnberg, Karin Jirström, Ophir D. Klein, Zena Werb, Vicki Plaks

A real-time electronic symptom monitoring system for patients after discharge following surgery: a pilot study in cancer-related surgery

• Open Access
• Research article

H. S. Richards, J. M. Blazeby, A. Portal, R. Harding, T. Reed, T. Lander, K. A. Chalmers, R. Carter, R. Singhal, K. Absolom, G. Velikova, K. N. L. Avery

A predictive model for treatment response in patients with locally advanced esophageal squamous cell carcinoma after concurrent chemoradiotherapy: based on SUVmean and NLR

• Open Access
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Chunsheng Wang, Kewei Zhao, Shanliang Hu, Yong Huang, Li Ma, Yipeng Song, Minghuan Li

Prognostic value of lymph node to primary tumor standardized uptake value ratio in unresectable esophageal cancer

• Open Access
• Research article

Po-Jui Chen, Wing-Keen Yap, Yu-Chuan Chang, Chen-Kan Tseng, Yin-Kai Chao, Jason Chia-Hsun Hsieh, Ping-Ching Pai, Ching-Hsin Lee, Chan-Keng Yang, Albert Tsung-Ying Ho, Tsung-Min Hung

Alignment of preferences in the treatment of multiple myeloma – a discrete choice experiment of patient, carer, physician, and nurse preferences

• Open Access
• Research article

Simon J. Fifer, Kerrie-Anne Ho, Sean Lybrand, Laurie J. Axford, Steve Roach

Correlation study between flash dual source CT perfusion imaging and regional lymph node metastasis of non-small cell lung cancer

• Open Access
• Research article

Tingting Huang, Hui Sun, Xianli Luo, Xuemei Zhang, Kaiyuan Jin, Feng Wang, Lv Sun, Nianlan Cheng, Shuo Wu, Qin Lou, Bangguo Li

Weekly paclitaxel plus ramucirumab versus weekly nab-paclitaxel plus ramucirumab for unresectable advanced or recurrent gastric cancer with peritoneal dissemination refractory to first-line therapy—the P-SELECT trial (WJOG10617G)—a randomised phase II trial by the West Japan Oncology Group

• Open Access
• Study protocol

Kenro Hirata, Yasuo Hamamoto, Masahiko Ando, Chiyo K. Imamura, Kenichi Yoshimura, Kentaro Yamazaki, Shuichi Hironaka, Kei Muro

Viral infection and glioma: a meta-analysis of prognosis

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Zehao Cai, Shoubo Yang, Xiaoyan Li, Feng Chen, Wenbin Li

Longer-term recurrence rate after low versus high dose radioiodine ablation for differentiated thyroid Cancer in low and intermediate risk patients: a meta-analysis

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I. Vardarli, F. Weidemann, M. Aboukoura, K. Herrmann, I. Binse, R. Görges

Association of type 2 diabetes mellitus and antidiabetic medication with risk of prostate cancer: a population-based case-control study

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E. Lin, Hans Garmo, Mieke Van Hemelrijck, Jan Adolfsson, Pär Stattin, Björn Zethelius, Danielle Crawley

Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

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Jennifer L. S. Willoughby, Kelly George, Mark P. Roberto, Hang Gyeong Chin, Patrick Stoiber, Hyunjin Shin, Chandra Sekhar Pedamallu, Scott E. Schaus, Kevin Fitzgerald, Jagesh Shah, Ulla Hansen

Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment

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Guan-hua Hu, Yi-fei Cheng, Ai-dong Lu, Yu Wang, Ying-xi Zuo, Chen-hua Yan, Jun Wu, Yu-qian Sun, Pan Suo, Yu-hong Chen, Huan Chen, Yue-ping Jia, Kai-yan Liu, Wei Han, Lan-ping Xu, Le-ping Zhang, Xiao-jun Huang

Cerebrospinal fluid cytokines in metastatic group 3 and 4 medulloblastoma

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Sharon Y. Y. Low, Nurfahanah Bte Syed Sulaiman, Enrica E. K. Tan, Lee Ping Ng, Chik Hong Kuick, Kenneth T. E. Chang, Phua Hwee Tang, Ru Xin Wong, Wen Shen Looi, David C. Y. Low, Wan Tew Seow

Altered staining patterns and expression level of Engrailed-2 in benign prostatic hyperplasia and prostate Cancer predict prostatic disease progression

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Qi Li, Yibo Shi, Rigai Sa, Jun Hao, Jinhao Hu, Mulun Xiao, Chaoliang Wang, Liang Yan, Baoping Qiao, Guoxun Chen

Impact of liver fibrosis score on prognosis after common therapies for intrahepatic cholangiocarcinoma: a propensity score matching analysis

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Jian Xi Zhang, Peipei Li, Zhibin Chen, Huogui Lin, Zhezhen Cai, Weijia Liao, Zirong Pan

Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial

• Open Access
• Study protocol

Relinde I. Y. Lieverse, Evert J. Van Limbergen, Cary J. G. Oberije, Esther G. C. Troost, Sine R. Hadrup, Anne-Marie C. Dingemans, Lizza E. L. Hendriks, Franziska Eckert, Crispin Hiley, Christophe Dooms, Yolande Lievens, Monique C. de Jong, Johan Bussink, Xavier Geets, Vincenzo Valentini, Giuliano Elia, Dario Neri, Charlotte Billiet, Amir Abdollahi, David Pasquier, Pierre Boisselier, Ala Yaromina, Dirk De Ruysscher, Ludwig J. Dubois, Philippe Lambin

A prognostic model based on cell-cycle control predicts outcome of breast cancer patients

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Heli Repo, Eliisa Löyttyniemi, Samu Kurki, Lila Kallio, Teijo Kuopio, Kati Talvinen, Pauliina Kronqvist

Implementation of a nurse-led self-management support intervention for patients with cancer-related pain: a cluster randomized phase-IV study with a stepped wedge design (EvANtiPain)

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Silvia Raphaelis, Florian Frommlet, Hanna Mayer, Antje Koller

Evaluation of adverse effects of chemotherapy regimens of 5-fluoropyrimidines derivatives and their association with DPYD polymorphisms in colorectal cancer patients

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Reza Negarandeh, Ebrahim Salehifar, Fatemeh Saghafi, Hossein Jalali, Ghasem Janbabaei, Mohammad Javad Abdhaghighi, Anahita Nosrati

Black patients referred to a lung cancer screening program experience lower rates of screening and longer time to follow-up

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Michael Lake, Christine S. Shusted, Hee-Soon Juon, Russell K. McIntire, Charnita Zeigler-Johnson, Nathaniel R. Evans, Gregory C. Kane, Julie A. Barta

Establishment of a serological molecular model for the early diagnosis and progression monitoring of bone metastasis in lung cancer

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Xiaoyan Teng, Lirong Wei, Liming Han, Daliu Min, Yuzhen Du

Cervical cancer screening in rural Ethiopia: a cross- sectional knowledge, attitude and practice study

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Friederike Ruddies, Muluken Gizaw, Brhanu Teka, Sarah Thies, Andreas Wienke, Andreas M. Kaufmann, Tamrat Abebe, Adamu Addissie, Eva Johanna Kantelhardt

Differentiation of suprasellar meningiomas from non-functioning pituitary macroadenomas by 18F-FDG and 13N-Ammonia PET/CT

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Lei Ding, Fangling Zhang, Qiao He, Zhoulei Li, Xinchong Shi, Ruocheng Li, Xiangsong Zhang

Multi-nanolayer drug delivery using radiofrequency plasma technology

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Iman Al Dybiat, Alibi Baitukha, Cynthia Pimpie, Rachid Kaci, Marc Pocard, Farzaneh Arefi Khonsari, Massoud Mirshahi

The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation

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Maria E. Morrissey, Róisín Byrne, Celina Nulty, Niamh H. McCabe, Niamh Lynam-Lennon, Clare T. Butler, Susan Kennedy, Dermot O’Toole, John Larkin, Paul McCormick, Brian Mehigan, Mary-Clare Cathcart, Joanne Lysaght, John V. Reynolds, Elizabeth J. Ryan, Margaret R. Dunne, Jacintha O’Sullivan

A comparative study of long interspersed element-1 protein immunoreactivity in cutaneous malignancies

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Mohammad Ali Zolfaghari, Abbas Karimi, Elham Kalantari, Alireza Korourian, Alireza Ghanadan, Kambiz Kamyab, Nafiseh Esmaili, Amir Nader Emami Razavi, Zahra Madjd

Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study

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Takumi Hasegawa, Tomoya Iga, Daisuke Takeda, Rika Amano, Izumi Saito, Yasumasa Kakei, Junya Kusumoto, Akira Kimoto, Akiko Sakakibara, Masaya Akashi

Immune characterization of metastatic colorectal cancer patients post reovirus administration

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Ruwan Parakrama, Elisha Fogel, Carol Chandy, Titto Augustine, Matt Coffey, Lydia Tesfa, Sanjay Goel, Radhashree Maitra

What are the benefits and harms of risk stratified screening as part of the NHS breast screening Programme? Study protocol for a multi-site non-randomised comparison of BC-predict versus usual screening (NCT04359420)

• Open Access
• Study protocol

David P. French, Susan Astley, Adam R. Brentnall, Jack Cuzick, Richard Dobrashian, Stephen W. Duffy, Louise S. Gorman, Elaine F. Harkness, Fiona Harrison, Michelle Harvie, Anthony Howell, Andrew Jerrison, Matthew Machin, Anthony J. Maxwell, Lorna McWilliams, Katherine Payne, Nadeem Qureshi, Helen Ruane, Sarah Sampson, Paula Stavrinos, Emma Thorpe, Fiona Ulph, Tjeerd van Staa, Victoria Woof, D. Gareth Evans

Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma

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Da Hyun Kang, Sung Soo Jung, Min-Kyung Yeo, Da Hye Lee, Geon Yoo, Sang Yeon Cho, In-Jae Oh, Ju-Ock Kim, Hee Sun Park, Chaeuk Chung, Jeong Eun Lee

Immune landscape of human prostate cancer: immune evasion mechanisms and biomarkers for personalized immunotherapy

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Mayassa J. Bou-Dargham, Linlin Sha, Qing-Xiang Amy Sang, Jinfeng Zhang

The effect of pericolic lymph nodes metastasis beyond 10 cm proximal to the tumor on patients with rectal cancer

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Xuyang Yang, Erliang Zheng, Lina Ye, Chaoyang Gu, Tao Hu, Dan Jiang, Du He, Bing Wu, Qinbing Wu, Tinghan Yang, Mingtian Wei, Wenjian Meng, Xiangbing Deng, Ziqiang Wang, Zongguang Zhou

Study protocol of the HYPER-LIV01 trial: a multicenter phase II, prospective and randomized study comparing simultaneous portal and hepatic vein embolization to portal vein embolization for hypertrophy of the future liver remnant before major hepatectomy for colo-rectal liver metastases

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• Study protocol

Emmanuel Deshayes, Lauranne Piron, Antoine Bouvier, Bruno Lapuyade, Emilie Lermite, Laurent Vervueren, Christophe Laurent, Jean-Baptiste Pinaquy, Patrick Chevallier, Anthony Dohan, Agnès Rode, Christian Sengel, Chloé Guillot, François Quenet, Boris Guiu

Prognostic characterization of OAS1/OAS2/OAS3/OASL in breast cancer

• Open Access
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Yujie Zhang, Chaoran Yu

Plasma omega-3 polyunsaturated fatty acids and recurrence of endometrial cancer

• Open Access
• Research article

Peiqin Li, Boer Shan, Keyu Jia, Fan Hu, Ying Xiao, Jusheng Zheng, Yu-Tang Gao, Huaying Wang, Ying Gao

Self-identity, lived experiences, and challenges of breast, cervical, and prostate cancer survivorship in Mexico: a qualitative study

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Felicia Marie Knaul, Svetlana V. Doubova, María Cecilia Gonzalez Robledo, Alessandra Durstine, Gabriela Sophia Pages, Felicia Casanova, Hector Arreola-Ornelas

Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study

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Stefanie Zorn, Janine Ehret, Rebecca Schäuble, Beate Rautenberg, Gabriele Ihorst, Hartmut Bertz, Paul Urbain, Anna Raynor

Diagnosis of triple negative breast cancer based on radiomics signatures extracted from preoperative contrast-enhanced chest computed tomography

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Qingliang Feng, Qiang Hu, Yan Liu, Tao Yang, Ziyi Yin

RETRACTED ARTICLE: The microRNA-130a-5p/RUNX2/STK32A network modulates tumor invasive and metastatic potential in non-small cell lung cancer

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Fang Ma, Yangchun Xie, Yiyu Lei, Zengshuyu Kuang, Xianling Liu

Prognostic value of circulating tumor cells detected with the CellSearch system in esophageal cancer patients: a systematic review and meta-analysis

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Yiding Li, Guiling Wu, Wanli Yang, Xiaoqian Wang, Lili Duan, Liaoran Niu, Yujie Zhang, Jinqiang Liu, Liu Hong, Daiming Fan

Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

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Zhiyang Peng, Qing Guan, Jianfei Luo, Wenhong Deng, Jiasheng Liu, Ruicheng Yan, Weixing Wang

Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells

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Qian Pu, Yan-rong Lv, Ke Dong, Wen-wen Geng, Hai-dong Gao

Prognostic significance of branched-chain amino acid transferase 1 and CD133 in triple-negative breast cancer

• Open Access
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Yu Song, Bin Zhao, Yali Xu, Xinyu Ren, Yan Lin, Liangrui Zhou, Qiang Sun

Immune-related genes in tumor-specific CD4+ and CD8+ T cells in colon cancer

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Xi Yang, Wei Wu, Yuefen Pan, Qing Zhou, Jiamin Xu, Shuwen Han

Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemia

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Chao Guo, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li, Ya-yue Gao

Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas

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Jan Rehkaemper, Michael Korenkov, Alexander Quaas, Josef Rueschoff, Aylin Pamuk, Thomas Zander, Axel M. Hillmer, Reinhard Buettner, Arnulf Heinrich Hoelscher, Christiane Josephine Bruns, Heike Loeser, Hakan Alakus, Birgid Schoemig-Markiefka

DNA methylation signatures of Prostate Cancer in peripheral T-cells

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Ali Mehdi, David Cheishvili, Ani Arakelian, Tarek A. Bismar, Moshe Szyf, Shafaat A. Rabbani

Does increased body mass index lead to elevated prostate cancer risk? It depends on waist circumference

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Jin Bong Choi, Jun-Pyo Myong, Yunhee Lee, Inah Kim, Jung Ho Kim, Sung-Hoo Hong, U-Syn Ha

Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma

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Rami Mäkelä, Antti Arjonen, Ville Härmä, Nina Rintanen, Lauri Paasonen, Tobias Paprotka, Kerstin Rönsch, Teijo Kuopio, Juha Kononen, Juha K. Rantala

Permanent iodine-125 brachytherapy for patients with progressive or recurrent high-grade gliomas

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Congxiao Wang, Shifeng Liu, Lijing Peng, Kaixian Zhang, Wei Li, Hao Zhang, Ying Luan, Peishun Li, Xiaokun Hu

Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer

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Erdem Altunel, Roham S. Roghani, Kai-Yuan Chen, So Young Kim, Shannon McCall, Kathryn E. Ware, Xiling Shen, Jason A. Somarelli, David S. Hsu

Correction to: Comparison of minimally invasive Ivor Lewis esophagectomy and left transthoracic esophagectomy in esophageal squamous cell carcinoma patients: a propensity score-matched analysis

• Open Access
• Correction

Qi Wang, Zixiang Wu, Tianwei Zhan, Shuai Fang, Sai Zhang, Gang Shen, Ming Wu

Nutritional status according to the mini nutritional assessment (MNA)® as potential prognostic factor for health and treatment outcomes in patients with cancer – a systematic review

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G. Torbahn, T. Strauss, C. C. Sieber, E. Kiesswetter, D. Volkert

Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer

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Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes, Han-Gang Yu

Imaging features and prognostic value of 18F-FDG PET/CT detection of soft-tissue metastasis from lung cancer: a retrospective study

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Tingting Xu, Xinyi Zhang, Shumao Zhang, Chunfeng Liu, Wenhui Fu, Chengrun Zeng, Yue Chen

MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma

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Pierre-Antoine Bissey, Mona Teng, Jacqueline H. Law, Wei Shi, Jeff P. Bruce, Valentin Petit, Sai W. Tsao, Kenneth W. Yip, Fei-Fei Liu

Prediction of lymph node metastasis by tumor-infiltrating lymphocytes in T1 breast cancer

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Koji Takada, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Rika Kouhashi, Akimichi Yabumoto, Tamami Morisaki, Masatsune Shibutani, Tsutomu Takashima, Hisakazu Fujita, Kosei Hirakawa, Masaichi Ohira

Cost-effectiveness analysis of proton beam therapy for treatment decision making in paranasal sinus and nasal cavity cancers in China

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Guo Li, Bo Qiu, Yi-Xiang Huang, Jerome Doyen, Pierre-Yves Bondiau, Karen Benezery, Yun-Fei Xia, Chao-Nan Qian

Integration of genomics, metagenomics, and metabolomics to identify interplay between susceptibility alleles and microbiota in adenoma initiation

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Jacob E. Moskowitz, Anthony G. Doran, Zhentian Lei, Susheel B. Busi, Marcia L. Hart, Craig L. Franklin, Lloyd W. Sumner, Thomas M. Keane, James M. Amos-Landgraf

Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies

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Junyi Wang, Yaning Cai, Fangfang Yu, Zhiguang Ping, Li Liu

High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma

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Yanfen Feng, Shumei Yan, Yuhua Huang, Qitao Huang, Fang Wang, Yiyan Lei

Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia

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I-Ming Kuo, Jih-Jong Lee, Yu-Shan Wang, Hsin-Chien Chiang, Cheng-Chung Huang, Pei-Jong Hsieh, Winston Han, Chiao-Hsu Ke, Albert T. C. Liao, Chen-Si Lin

Prevalence and incidence of cancer related lymphedema in low and middle-income countries: a systematic review and meta-analysis

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Eric Torgbenu, Tim Luckett, Mark A. Buhagiar, Sungwon Chang, Jane L. Phillips

An agent-based model of prostate Cancer bone metastasis progression and response to Radium223

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Stefano Casarin, Eleonora Dondossola

MAGE-A4, NY-ESO-1 and SAGE mRNA expression rates and co-expression relationships in solid tumours

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Mikiya Ishihara, Shinichi Kageyama, Yoshihiro Miyahara, Takeshi Ishikawa, Shugo Ueda, Norihito Soga, Hiroaki Naota, Katsumi Mukai, Naozumi Harada, Hiroaki Ikeda, Hiroshi Shiku

Tumor necrosis as a poor prognostic predictor on postoperative survival of patients with solitary small hepatocellular carcinoma

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Yi-hong Ling, Jie-wei Chen, Shi-hong Wen, Chao-yun Huang, Peng Li, Liang-he Lu, Jie Mei, Shao-hua Li, Wei Wei, Mu-yan Cai, Rong-ping Guo

Nomograms that predict the survival of patients with adenocarcinoma in villous adenoma of the colorectum: a SEER-based study

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Chao-Tao Tang, Ling Zeng, Jing Yang, Chunyan Zeng, Youxiang Chen

Cardio-toxicity among patients with sarcoma: a cardio-oncology registry

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Sivan Shamai, Zach Rozenbaum, Ofer Merimsky, Matthew Derakhshesh, Yonatan Moshkovits, Joshua Arnold, Yan Topilsky, Yaron Arbel, Michal Laufer-Perl

Sparing the hippocampus and the hypothalamic- pituitary region during whole brain radiotherapy: a volumetric modulated arc therapy planning study

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P. Mehta, S. Janssen, F. B. Fahlbusch, S. M. Schmid, J. Gebauer, F. Cremers, C. Ziemann, M. Tartz, D. Rades

Texture analysis of MR images to identify the differentiated degree in hepatocellular carcinoma: a retrospective study

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Mengmeng Feng, Mengchao Zhang, Yuanqing Liu, Nan Jiang, Qian Meng, Jia Wang, Ziyun Yao, Wenjuan Gan, Hui Dai

Analytical evaluation of the clonoSEQ Assay for establishing measurable (minimal) residual disease in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple myeloma

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Travers Ching, Megan E. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter, Jeffrey M. Tracy, Michelle S. Steen, Ryan P. Brown, Srivatsa Venkatasubbarao, Nicholas K. Akers, Marissa Vignali, Martin E. Moorhead, Drew Watson, Ryan O. Emerson, Tobias P. Mann, B. Melina Cimler, Pamela L. Swatkowski, Ilan R. Kirsch, Charles Sang, Harlan S. Robins, Bryan Howie, Anna Sherwood

Impact of breath-hold level on positional error aligned by stent/Lipiodol in Hepatobiliary radiotherapy with breath-hold respiratory control

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Tzu-Jie Huang, Yun Tien, Jian-Kuen Wu, Wen-Tao Huang, Jason Chia-Hsien Cheng

Postoperative adjuvant treatment strategy for hepatocellular carcinoma with microvascular invasion: a non-randomized interventional clinical study

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Liming Wang, Weihu Wang, Weiqi Rong, Zhuo Li, Fan Wu, Yunhe Liu, Yiling Zheng, Kai Zhang, Tana Siqin, Mei Liu, Bo Chen, Jianxiong Wu

Sterile, abscess-like cerebral lesion during trastuzumab therapy after HER2 status switch in a triple negative breast cancer patient: a case report and literature review

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• Case report

Tamás Mezei, Melinda Hajdu, Gábor Czigléczki, Gábor Lotz, Judit Kocsis, Janina Kulka, Anna Horváth

Impact of the faecal immunochemical test on colorectal cancer survival

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María Angeles Gutierrez-Stampa, Vanessa Aguilar, Cristina Sarasqueta, Joaquín Cubiella, Isabel Portillo, Luis Bujanda

Synergisms of genome and metabolism stabilizing antitumor therapy (GMSAT) in human breast and colon cancer cell lines: a novel approach to screen for synergism

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Jérôme Ruhnau, Jonas Parczyk, Kerstin Danker, Britta Eickholt, Andreas Klein

The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis

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Miao Wan, Xianggui Luo, Juan Wang, Louis. B Mvogo Ndzana, Chen Chang, Zhenfen Li, Jianglin Zhang

Etoposide-mediated interleukin-8 secretion from bone marrow stromal cells induces hematopoietic stem cell mobilization

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Ka-Won Kang, Seung-Jin Lee, Ji Hye Kim, Byung-Hyun Lee, Seok Jin Kim, Yong Park, Byung Soo Kim

PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets

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Siying He, Wenjie Du, Menglan Li, Ming Yan, Fang Zheng

Fluctuating expression of miR-584 in primary and high-grade gastric cancer

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Laleh Ebrahimi Ghahnavieh, Hossein Tabatabaeian, Zhaleh Ebrahimi Ghahnavieh, Mohammad Amin Honardoost, Mansoureh Azadeh, Mohamad Moazeni Bistgani, Kamran Ghaedi

Design and methods of a national, multicenter, randomized and controlled trial to assess the efficacy of a physical activity program to improve health-related quality of life and reduce fatigue in women with metastatic breast cancer: ABLE02 trial

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• Study protocol

Lidia Delrieu, Amélie Anota, Olivier Trédan, Damien Freyssenet, Aurélia Maire, Brice Canada, Baptiste Fournier, Olivia Febvey-Combes, Frank Pilleul, Amine Bouhamama, Christophe Caux, Florence Joly, Béatrice Fervers, Vincent Pialoux, David Pérol, Olivia Pérol

Incidence, prevalence, mortality, and causes of death in Waldenström macroglobulinemia: a nationwide, population-based cohort study

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Seri Jeong, Seom Gim Kong, Da Jung Kim, Sangjin Lee, Ho Sup Lee

The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma

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Marcela García, Maria Belen Palma, Jerome Verine, Santiago Miriuka, Ana M. Inda, Ana L. Errecalde, François Desgrandchamps, Edgardo D. Carosella, Diana Tronik-Le Roux

Sarcoma epidemiology and cancer-related hospitalisation in Western Australia from 1982 to 2016: a descriptive study using linked administrative data

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Cameron M. Wright, Georgia Halkett, Richard Carey Smith, Rachael Moorin

NR2F2 plays a major role in insulin-induced epithelial-mesenchymal transition in breast cancer cells

• Open Access
• Research article

Baili Xia, Lijun Hou, Huan Kang, Wenhui Chang, Yi Liu, Yanli Zhang, Yi Ding

Starvation stress attenuates the miRNA-target interaction in suppressing breast cancer cell proliferation

• Open Access
• Research article

Jinhui Lü, Chuyi Zhang, Junyi Han, Zhen Xu, Yuan Li, Lixiao Zhen, Qian Zhao, Yuefan Guo, Zhaohui Wang, Evelyne Bischof, Zuoren Yu

Oncolytic vaccinia virus GLV-1h68 exhibits profound antitumoral activities in cell lines originating from neuroendocrine neoplasms

• Open Access
• Research article

Linus D. Kloker, Susanne Berchtold, Irina Smirnow, Julia Beil, Andreas Krieg, Bence Sipos, Ulrich M. Lauer

The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun

• Open Access
• Research article

Hayaa Moeed Alhuthali, Tracey D. Bradshaw, Kuan-Hon Lim, Toh-Seok Kam, Claire H. Seedhouse

A refractory case of CDK4-amplified spinal astrocytoma achieving complete response upon treatment with a Palbociclib-based regimen:a case report

• Open Access
• Case report

Jietao Lin, Ling Yu, Yuanfeng Fu, Hanrui Chen, Xinting Zheng, Shutang Wang, Chan Gao, Yang Cao, Lizhu Lin

Head & neck acinar cell carcinoma: a population-based study using the seer registry

• Open Access
• Research article

Feiluore Yibulayin, Lei Feng, Meng Wang, Meng-meng Lu, Yuan Luo, Hui Liu, Zhi-cheng Yang, Alimujiang Wushou

CCL18-NIR1 promotes oral cancer cell growth and metastasis by activating the JAK2/STAT3 signaling pathway

• Open Access
• Research article

Xiao Jiang, Zhijie Huang, Xiang Sun, Xianghuai Zheng, Jingpeng Liu, Jun Shen, Bo Jia, Haiyun Luo, Zhaoyi Mai, Guodong Chen, Jianjiang Zhao

Meta-analysis examining overall survival in patients with pancreatic cancer treated with second-line 5-fluorouracil and oxaliplatin-based therapy after failing first-line gemcitabine-containing therapy: effect of performance status and comparison with other regimens

• Open Access
• Research article

Zev A. Wainberg, Kynan Feeney, Myung Ah Lee, Andrés Muñoz, Antonio Cubillo Gracián, Sara Lonardi, Baek-Yeol Ryoo, Annie Hung, Yong Lin, Johanna Bendell, J. Randolph Hecht

Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells

• Open Access
• Research article

Shu-Ting Pan, Ji Zhou, Fang Yang, Shu-Feng Zhou, Tao Ren

Design of the PROstate cancer follow-up care in Secondary and Primary hEalth Care study (PROSPEC): a randomized controlled trial to evaluate the effectiveness of primary care-based follow-up of localized prostate cancer survivors

• Open Access
• Study protocol

Barbara M. Wollersheim, Kristel M. van Asselt, Henk G. van der Poel, Henk C. P. M. van Weert, Michael Hauptmann, Valesca P. Retèl, Neil K. Aaronson, Lonneke V. van de Poll-Franse, Annelies H. Boekhout

Study protocol for an open-label, single-arm, phase Ib/II study of combination of toripalimab, nab-paclitaxel, and gemcitabine as the first-line treatment for patients with unresectable pancreatic ductal adenocarcinoma

• Open Access
• Study protocol

Lin Shui, Ke Cheng, Xiaofen Li, Pixian Shui, Xiaohan Zhou, Jian Li, Cheng Yi, Dan Cao

Thyroid cancer in Ecuador

• Open Access
• Correspondence

Enrique López Gavilanez, Noemí Bautista Litardo, Manuel Navarro Chávez, Mario Hernández Bonilla, Angel Segale Bajaña

Relationship between aspirin use of esophageal, gastric and colorectal cancer patient survival: a meta-analysis

• Open Access
• Research article

Ju-Li Lin, Jian-Xian Lin, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin, Chang-Ming Huang

Sentinel node theory helps tracking of primary lesions of cancers of unknown primary

• Open Access
• Research article

Yilin Shao, Xin Liu, Silong Hu, Yingjian Zhang, Wentao Li, Xiaoyan Zhou, Qifeng Wang, Yifeng Hou, Yong Chen, Yanli Wang, Yaohui Wang, Zhiguo Luo, Xichun Hu

Farnesoid X receptor as marker of osteotropism of breast cancers through its role in the osteomimetism of tumor cells

• Open Access
• Research article

L. Absil, F. Journé, D. Larsimont, J. J. Body, L. Tafforeau, D. Nonclercq

Challenges for cancer patients returning home during SARS-COV-19 pandemic after medical tourism - a consensus report by the emirates oncology task force

• Open Access
• Review

Humaid O. Al-Shamsi, Ibrahim Abu-Gheida, Shabeeha K. Rana, Neil Nijhawan, Ahmed S. Abdulsamad, Sadir Alrawi, Mohamed Abuhaleeqa, Taleb M. Almansoori, Thamir Alkasab, Essa M. Aleassa, Martine C. McManus

Adjuvant Transarterial chemoembolization does not influence recurrence-free or overall survival in patients with combined hepatocellular carcinoma and Cholangiocarcinoma after curative resection: a propensity score matching analysis

• Open Access
• Research article

Wei-Ren Liu, Meng-Xin Tian, Chen-Yang Tao, Zheng Tang, Yu-Fu Zhou, Shu-Shu Song, Xi-Fei Jiang, Han Wang, Pei-Yun Zhou, Wei-Feng Qu, Yuan Fang, Zhen-Bin Ding, Jian Zhou, Jia Fan, Ying-Hong Shi

Gynaecological cancer in Caribbean women: data from the French population-based cancer registries of Martinique, Guadeloupe and French Guiana (2007–2014)

• Open Access
• Research article

Clarisse Joachim, Jacqueline Véronique-Baudin, Laure Desroziers, Édouard Chatignoux, Sophie Belliardo, Juliette Plenet, Jonathan Macni, Stephen Ulric-Gervaise, Jessica Peruvien, Bernard Bhakkan-Mambir, Jacqueline Deloumeaux

Evaluation of MiR-1908-3p as a novel serum biomarker for breast cancer and analysis its oncogenic function and target genes

• Open Access
• Research article

Youzhi Zhu, Qingshui Wang, Yun Xia, Xiaoxue Xiong, Shuyun Weng, Huizhen Ni, Yan Ye, Ling Chen, Junyu Lin, Yajuan Chen, Haitao Niu, Xiangjin Chen, Yao Lin

Cost-effectiveness analysis of repeated self-sampling for HPV testing in primary cervical screening: a randomized study

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• Research article

Riina Aarnio, Ellinor Östensson, Matts Olovsson, Inger Gustavsson, Ulf Gyllensten

Management of medically inoperable and tyrosine kinase inhibitor-naïve early-stage lung adenocarcinoma with epidermal growth factor receptor mutations: a retrospective multi-institutional analysis

• Open Access
• Research article

Yuemei Sun, Mengwan Wu, Mingxiu Zhou, Xing Luo, Yan Guo, Hansong Bai, Zican Zhang, Wei Tian, Xiaoshan Wang, Yifeng Bai, Xueqiang Zhu, Haixia Pan, Ying Deng, Honglin Hu, Jianling Xia, Xinbao Hao, Liangfu Han, Min Wei, Yingyi Liu, Ming Zeng

IMMUNEPOTENT CRP induces DAMPS release and ROS-dependent autophagosome formation in HeLa and MCF-7 cells

• Open Access
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Ana Carolina Martínez-Torres, Alejandra Reyes-Ruiz, Kenny Misael Calvillo-Rodriguez, Karla Maria Alvarez-Valadez, Ashanti C. Uscanga-Palomeque, Reyes S. Tamez-Guerra, Cristina Rodríguez-Padilla

Fibroadenoma versus phyllodes tumor: a vexing problem revisited!

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Santosh Tummidi, Kanchan Kothari, Mona Agnihotri, Leena Naik, Prashant Sood

Real-world efficacy and safety of two doses of cabazitaxel (20 or 25 mg/m2) in patients with castration-resistant prostate cancer: results of a Japanese post-marketing surveillance study

• Open Access
• Research article

Hideyasu Matsuyama, Nobuaki Matsubara, Hirotaka Kazama, Takeshi Seto, Shoko Tsukube, Kazuhiro Suzuki

Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib

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Lea Bornemann, Marc Schuster, Saskia Schmitz, Charlyn Sobczak, Clara Bessen, Simon F. Merz, Karl-Heinz Jöckel, Thomas Haverkamp, Matthias Gunzer, Joachim R. Göthert

Global targetome analysis reveals critical role of miR-29a in pancreatic stellate cell mediated regulation of PDAC tumor microenvironment

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Shatovisha Dey, Sheng Liu, Tricia D. Factora, Solaema Taleb, Primavera Riverahernandez, Lata Udari, Xiaoling Zhong, Jun Wan, Janaiah Kota

A single-arm confirmatory trial of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma: Japan Clinical Oncology Group study (JCOG1605, JCOG-PCAS protocol)

• Open Access
• Study protocol

Kohei Oashi, Taro Shibata, Kenjiro Namikawa, Akira Takahashi, Kenji Yokota, Eiji Nakano, Yukiko Teramoto, Arata Tsutsumida, Taku Maeda, Naoya Yamazaki

Pyrotinib with trastuzumab and aromatase inhibitors as first-line treatment for HER2 positive and hormone receptor positive metastatic or locally advanced breast cancer: study protocol of a randomized controlled trial

• Open Access
• Study protocol

Changjun Wang, Yan Lin, Yidong Zhou, Feng Mao, Hanjiang Zhu, Jinghong Guan, Xiaohui Zhang, Songjie Shen, Xin Huang, Chang Chen, Ru Yao, Jialin Zhao, Qiang Sun

The relationship between retroperitoneal lymphadenectomy and survival in advanced ovarian cancer patients

• Open Access
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Chenyan Fang, Yingli Zhang, Lingqin Zhao, Xi Chen, Liang Xia, Ping Zhang

Exercise as a diagnostic and therapeutic tool for preventing cardiovascular morbidity in breast cancer patients– the BReast cancer EXercise InTervention (BREXIT) trial protocol

• Open Access
• Study protocol

Stephen J. Foulkes, Erin J. Howden, Yoland Antill, Sherene Loi, Agus Salim, Mark J. Haykowsky, Robin M. Daly, Steve F. Fraser, Andre La Gerche

Correlation between immune-related adverse events and prognosis in patients with various cancers treated with anti PD-1 antibody

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Hiroshi Matsuoka, Takahiro Hayashi, Karen Takigami, Kazuyoshi Imaizumi, Ryoichi Shiroki, Naoki Ohmiya, Kazumitsu Sugiura, Kenji Kawada, Akira Sawaki, Koutaro Maeda, Yousuke Ando, Ichiro Uyama

Prospective study of oncologic outcomes after laparoscopic modified complete mesocolic excision for non-metastatic right colon cancer (PIONEER study): study protocol of a multicentre single-arm trial

• Open Access
• Study protocol

Seung Yoon Yang, Min Jung Kim, Bong-Hyeon Kye, Yoon Dae Han, Min Soo Cho, Seung-Yong Jeong, Hyeon-Min Cho, Hyunki Kim, Gyeong Hoon Kang, Seung Ho Song, Jun Seok Park, Ji-Seon Kim, Soo Yeun Park, Jin Kim, Byung Soh Min

Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with non-squamous non-small cell lung cancer in New Zealand

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Phyu Sin Aye, Sandar Tin Tin, Mark James McKeage, Prashannata Khwaounjoo, Alana Cavadino, J. Mark Elwood

LncRNA MEG3 rs3087918 was associated with a decreased breast cancer risk in a Chinese population: a case-control study

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Yi Zheng, Meng Wang, Shuqian Wang, Peng Xu, Yujiao Deng, Shuai Lin, Na Li, Kang Liu, Yuyao Zhu, Zhen Zhai, Ying Wu, Zhijun Dai, Gaixia Zhu

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis

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Jordana Maria Azevedo Martins, Silvia Helena Rabelo-Santos, Maria Cristina do Amaral Westin, Luiz Carlos Zeferino

Transcriptomic insight into salinomycin mechanisms in breast cancer cell lines: synergistic effects with dasatinib and induction of estrogen receptor β

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Vanessa Bellat, Alice Verchère, Sally A. Ashe, Benedict Law

Clinicopathological significance and prognosis of long noncoding RNA SNHG16 expression in human cancers: a meta-analysis

• Open Access
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Ruonan Jiao, Wei Jiang, Xin Wei, Mengpei Zhang, Si Zhao, Guangming Huang

A prospective, randomized study of Toremifene vs. tamoxifen for the treatment of premenopausal breast cancer: safety and genital symptom analysis

• Open Access
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Jin Hong, Jiahui Huang, Lili Shen, Siji Zhu, Weiqi Gao, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen

Comparison of adenocarcinoma and adenosquamous carcinoma prognoses in Chinese patients with FIGO stage IB-IIA cervical cancer following radical surgery

• Open Access
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Xiaojing Zhang, Zunfu Lv, Xiaoxian Xu, Zhuomin Yin, Hanmei Lou

Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy

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Qingyuan Feng, Xuzhao Bian, Xuan Liu, Ying Wang, Huiting Zhou, Xiaojing Ma, Chunju Quan, Yi Yao, Zhongliang Zheng

A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database

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Bo Jia, Qiwen Zheng, Jingjing Wang, Hongyan Sun, Jun Zhao, Meina Wu, Tongtong An, Yuyan Wang, Minglei Zhuo, Jianjie Li, Xue Yang, Jia Zhong, Hanxiao Chen, Yujia Chi, Xiaoyu Zhai, Ziping Wang

Distribution pattern and prognosis of metastatic lymph nodes in cervical posterior to level V in nasopharyngeal carcinoma patients

• Open Access
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Chaoyang Jiang, Hui Gao, Ling Zhang, Hua Li, Tao Zhang, Ji Ma, Bisheng Liu

Network-based identification of biomarkers for colon adenocarcinoma

• Open Access
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Fuyan Hu, Qing Wang, Zhiyuan Yang, Zeng Zhang, Xiaoping Liu

Short-term outcomes of robotic- versus laparoscopic-assisted Total Gastrectomy for advanced gastric Cancer: a propensity score matching study

• Open Access
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Changdong Yang, Yan Shi, Shaohui Xie, Jun Chen, Yongliang Zhao, Feng Qian, Yingxue Hao, Bo Tang, Peiwu Yu

Treatment patterns and health outcomes in metastatic renal cell carcinoma patients treated with targeted systemic therapies in the UK

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Robert Hawkins, Kate Fife, Michael Hurst, Meng Wang, Niroshini Naicker, Sarah Nolasco, Tim Eisen, Athena Matakidou, Jason Gordon

The prognosis of hepatoid adenocarcinoma of the stomach: a propensity score-based analysis

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Kai Zhou, Anqiang Wang, Sheng Ao, Jiahui Chen, Ke Ji, Qifei He, Xin Ji, Xiaojiang Wu, Ji Zhang, Zhongwu Li, Zhaode Bu, Jiafu Ji

The predominant expression of cancer stem cell marker ALDH1A3 in tumor infiltrative area is associated with shorter overall survival of human glioblastoma

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Chao Gan, Daniela Pierscianek, Nicolai El Hindy, Yahya Ahmadipour, Kathy Keyvani, Ulrich Sure, Yuan Zhu

Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells

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Fengyu Zhang, Ruilai Liu, Haishi Zhang, Cheng Liu, Chunfang Liu, Yuan Lu

The prognostic values of m6A RNA methylation regulators in uveal melanoma

• Open Access
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Jing Tang, Qi Wan, Jianqun Lu

Effect of neoadjuvant therapy on breast cancer biomarker profile

• Open Access
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Laura Rey-Vargas, Juan Carlos Mejía-Henao, María Carolina Sanabria-Salas, Silvia J. Serrano-Gomez

Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer

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Maryam Soleimani Dodaran, Simone Borgoni, Emre Sofyalı, Pernette J. Verschure, Stefan Wiemann, Perry D. Moerland, Antoine H. C. van Kampen

Three-year outcome after transanal versus laparoscopic total mesorectal excision in locally advanced rectal cancer: a multicenter comparative analysis

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F. B. de Lacy, S. X. Roodbeen, J. Ríos, J. van Laarhoven, A. Otero-Piñeiro, R. Bravo, T. Visser, R. van Poppel, S. Valverde, R. Hompes, C. Sietses, A. Castells, W. A. Bemelman, P. J. Tanis, A. M. Lacy

Therapeutic effect of dual CAR-T targeting PDL1 and MUC16 antigens on ovarian cancer cells in mice

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Tong Li, Jiandong Wang

Clinical characteristics and prognosis of anal squamous cell carcinoma: a retrospective audit of 144 patients from 11 cancer hospitals in southern China

• Open Access
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Yong Lu, Xiaohao Wang, Peiyang Li, Tao Zhang, Jiaming Zhou, Yufeng Ren, Yi Ding, Haihua Peng, Qichun Wei, Kaiyun You, Jason J. Ong, Christopher K. Fairley, Andrew E. Grulich, Meijin Huang, Yuanhong Gao, Huachun Zou

Risk stratified breast cancer screening: UK healthcare policy decision-making stakeholders’ views on a low-risk breast screening pathway

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Lorna McWilliams, Victoria G. Woof, Louise S. Donnelly, Anthony Howell, D. Gareth Evans, David P. French

RETRACTED ARTICLE: Invasion inhibition in pancreatic cancer using the oral iron chelating agent deferasirox

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Shogo Amano, Seiji Kaino, Shuhei Shinoda, Hirofumi Harima, Toshihiko Matsumoto, Koichi Fujisawa, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Isao Sakaida

LINC00511 as a prognostic biomarker for human cancers: a systematic review and meta-analysis

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Yannick Luther Agbana, Manzama-Esso Abi, Yueli Ni, Guohang Xiong, Jing Chen, Fang Yun, Zihan Yi, Qiao Zhang, Zhe Yang, Yingmin Kuang, Yuechun Zhu

AtezoTRIBE: a randomised phase II study of FOLFOXIRI plus bevacizumab alone or in combination with atezolizumab as initial therapy for patients with unresectable metastatic colorectal cancer

• Open Access
• Study protocol

Carlotta Antoniotti, Beatrice Borelli, Daniele Rossini, Filippo Pietrantonio, Federica Morano, Lisa Salvatore, Sara Lonardi, Federica Marmorino, Stefano Tamberi, Salvatore Corallo, Giampaolo Tortora, Francesca Bergamo, Di Stefano Brunella, Alessandra Boccaccino, Elisa Grassi, Patrizia Racca, Emiliano Tamburini, Giuseppe Aprile, Roberto Moretto, Luca Boni, Alfredo Falcone, Chiara Cremolini

Efficacy and safety of nivolumab for advanced gastric cancer patients with poor performance statuses

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Toshihiko Matsumoto, Yosuke Yamamoto, Yusuke Kuriona, Ukyo Okazaki, Shogo Kimura, Kou Miura, Takao Tsuduki, Takanori Watanabe, Yusuke Mastumoto, Masahiro Takatani

A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

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Khayal Al-Khayal, Mansoor-Ali Vaali-Mohammed, Mohammed Elwatidy, Thamer Bin Traiki, Omar Al-Obeed, Mohammad Azam, Zahid Khan, Maha Abdulla, Rehan Ahmad

Differential associations of proinflammatory and anti-inflammatory cytokines with depression severity from noncancer status to breast cancer course and subsequent chemotherapy

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Bor-Show Tzang, Vincent Chin-Hung Chen, Ching-Chuan Hsieh, Wen-Ke Wang, Yi-Ping Weng, Hsing-Ying Ho, Ya-Ting Hsu, Han-Pin Hsaio, Jun-Cheng Weng, Yi-Lung Chen

Protocol of the QUATTRO-II study: a multicenter randomized phase II study comparing CAPOXIRI plus bevacizumab with FOLFOXIRI plus bevacizumab as a first-line treatment in patients with metastatic colorectal cancer

• Open Access
• Study protocol

Masaaki Miyo, Takeshi Kato, Takayuki Yoshino, Takeharu Yamanaka, Hideaki Bando, Hironaga Satake, Kentaro Yamazaki, Hiroya Taniguchi, Eiji Oki, Masahito Kotaka, Koji Oba, Yoshinori Miyata, Kei Muro, Yoshito Komatsu, Hideo Baba, Akihito Tsuji

A prospective feasibility study of one-year administration of adjuvant S-1 therapy for resected biliary tract cancer in a multi-institutional trial (Tokyo Study Group for Biliary Cancer: TOSBIC01)

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Osamu Itano, Yusuke Takemura, Norihiro Kishida, Eiji Tamagawa, Hiroharu Shinozaki, Ken Ikeda, Hidejiro Urakami, Shigenori Ei, Shigeo Hayatsu, Keiichi Suzuki, Tadayuki Sakuragawa, Masatsugu Ishii, Masaya Shito, Koichi Aiura, Hiroto Fujisaki, Kiminori Takano, Junichi Matsui, Takuya Minagawa, Masahiro Shinoda, Minoru Kitago, Yuta Abe, Hiroshi Yagi, Go Oshima, Shutaro Hori, Yuko Kitagawa

Effect of diabetes mellitus on survival in patients with gallbladder Cancer: a systematic review and meta-analysis

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Chen Jing, Zhengyi Wang, Xue Fu

Detection of genes mutations in cerebrospinal fluid circulating tumor DNA from neoplastic meningitis patients using next generation sequencing

• Open Access
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Yue Zhao, Jun Ying He, Jun Zhao Cui, Zi-Qi Meng, Yue Li Zou, Xiao Su Guo, Xin Chen, Xueliang Wang, Li-Tian Yan, Wei Xin Han, Chunyan Li, Li Guo, Hui Bu

Preoperative fibrinogen-to-albumin ratio, a potential prognostic factor for patients with stage IB-IIA cervical cancer

• Open Access
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Qiang An, Wei Liu, Yujia Yang, Bing Yang

A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility

• Open Access
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Justina Ucheojor Onwuka, Dapeng Li, Yupeng Liu, Hao Huang, Jing Xu, Ying Liu, Yuanyuan Zhang, Yashuang Zhao

Cancer cases and deaths attributable to lifestyle risk factors in Chile

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Leandro F. M. Rezende, Eliana Murata, Beatriz Giannichi, Luciana Yuki Tomita, Gabriela Arantes Wagner, Zila M. Sanchez, Carlos Celis-Morales, Gerson Ferrari

Efficient mutation screening for cervical cancers from circulating tumor DNA in blood

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Sun-Young Lee, Dong-Kyu Chae, Sung-Hun Lee, Yohan Lim, Jahyun An, Chang Hoon Chae, Byung Chul Kim, Jong Bhak, Dan Bolser, Dong-Hyu Cho

Low dose environmental radon exposure and breast tumor gene expression

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Cheng Peng, Natalie DuPre, Trang VoPham, Yujing J. Heng, Gabrielle M. Baker, Christopher A. Rubadue, Kimberly Glass, Abhijeet Sonawane, Oana Zeleznik, Peter Kraft, Susan E. Hankinson, A. Heather Eliassen, Jaime E. Hart, Francine Laden, Rulla M. Tamimi

Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review

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Achraf El Asri, Btissame Zarrouq, Khaoula El Kinany, Laila Bouguenouch, Karim Ouldim, Karima El Rhazi

The support and information needs of adolescents and young adults with cancer when active treatment ends

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Sarah Lea, Ana Martins, Lorna A. Fern, Matthew Bassett, Maria Cable, Gary Doig, Sue Morgan, Louise Soanes, Michael Whelan, Rachel M. Taylor

Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma

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Zhichao Tian, Fan Zhang, Po Li, Jiaqiang Wang, Jinpo Yang, Peng Zhang, Weitao Yao, Xin Wang

Risk factors of metachronous brain metastasis in patients with EGFR-mutated advanced non-small cell lung cancer

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Wen Ouyang, Jing Yu, Yan Zhou, Jing Hu, Zhao huang, Junhong Zhang, Conghua Xie

Is thyroid excision mandatory with laryngectomy in carcinoma larynx?

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Surendra Singh Baghel, Pawan Singhal, Namita Verma, Ritu Sehra, Rajeev Yadav, Sunita Agarwal, Man Prakash Sharma, D. P. Gupta

Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC)

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• Study protocol

Lara Bußmann, Simon Laban, Claus Wittekindt, Carmen Stromberger, Silke Tribius, Nikolaus Möckelmann, Arne Böttcher, Christian Stephan Betz, Jens Peter Klussmann, Volker Budach, Adrian Muenscher, Chia-Jung Busch

Assessment of the results and hematological side effects of 3D conformal and IMRT/ARC therapies delivered during craniospinal irradiation of childhood tumors with a follow-up period of five years

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Zoltán Lőcsei, Róbert Farkas, Kornélia Borbásné Farkas, Klára Sebestyén, Zsolt Sebestyén, Zoltán Musch, Ágnes Vojcek, Noémi Benedek, László Mangel, Gábor Ottóffy

Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer

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Andy Göbel, Valentina M. Zinna, Stefania Dell’Endice, Nikolai Jaschke, Jan Dominik Kuhlmann, Pauline Wimberger, Tilman D. Rachner

Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?

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Steffen M. Heckl, Marie Pellinghaus, Hans-Michael Behrens, Sandra Krüger, Stefan Schreiber, Christoph Röcken

Comprehensive analysis of spread through air spaces in lung adenocarcinoma and squamous cell carcinoma using the 8th edition AJCC/UICC staging system

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Meng Jia, Shili Yu, Jiaqi Yu, Yuemin Li, Hongwen Gao, Ping-Li Sun

Liquid-based cytology for the detection of cervical intraepithelial lesions in Jimma town, Ethiopia

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Getnet Tesfaw, Yesuf Ahmed, Lealem Gedefaw, Lamessa Dube, Samson Godu, Kirubel Eshetu, Mesfin Nigussie, Haftamu Hailekiros, Moses Joloba, Gelila Goba, Alemseged Abdissa

Clinical characteristics of hyperprogressive disease in NSCLC after treatment with immune checkpoint inhibitor: a systematic review and meta-analysis

• Open Access
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Yan Chen, Junjie Hu, Fangfang Bu, Haiping Zhang, Ke Fei, Peng Zhang

Dietary Approaches to Stop Hypertension (DASH) diets and breast cancer among women: a case control study

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Zeinab Heidari, Elahe Mohammadi, Vahideh Aghamohammadi, Saba Jalali, Arezoo Rezazadeh, Fatemeh Sedaghat, Mojan Assadi, Bahram Rashidkhani

Both p53 codon 72 Arg/Arg and pro/Arg genotypes in glioblastoma multiforme are associated with a better prognosis in bevacizumab treatment

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Chiung-Chyi Shen, Wen-Yu Cheng, Chung-Hsin Lee, Xue-Jun Dai, Ming-Tsang Chiao, Yea-Jiuen Liang, Wan-Yu Hsieh, Tsuo-Fei Mao, Guo-Shi Lin, Shou-Ren Chen, Bai-Shuan Liu, Jun-Peng Chen

Multiple formin proteins participate in glioblastoma migration

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Vanina D. Heuser, Aida Kiviniemi, Laura Lehtinen, Sune Munthe, Bjarne Winther Kristensen, Jussi P. Posti, Jussi O. T. Sipilä, Ville Vuorinen, Olli Carpén, Maria Gardberg

Study protocol of the Aerobic exercise and CogniTIVe functioning in women with breAsT cancEr (ACTIVATE) trial: a two-arm, two-centre randomized controlled trial

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• Study protocol

Jennifer Brunet, Meagan Barrett-Bernstein, Kendra Zadravec, Monica Taljaard, Nathalie LeVasseur, Amirrtha Srikanthan, Kelcey A. Bland, Barbara Collins, Julia W. Y. Kam, Todd C. Handy, Sherri Hayden, Christine Simmons, Andra M. Smith, Naznin Virji-Babul, Kristin L. Campbell

Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness

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Melanie Lindenberg, Valesca Retèl, Maartje Rohaan, Joost van den Berg, John Haanen, Wim van Harten

Methylation of WT1, CA10 in peripheral blood leukocyte is associated with breast cancer risk: a case-control study

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Anqi Ge, Song Gao, Yupeng Liu, Hui Zhang, Xuan Wang, Lei Zhang, Da Pang, Yashuang Zhao

Novel bioinformatic classification system for genetic signatures identification in diffuse large B-cell lymphoma

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Wei Zhang, Li Yang, Yu’ Qi Guan, Ke’ Feng Shen, Mei’ Lan Zhang, Hao’ Dong Cai, Jia’ Chen Wang, Ying Wang, Liang Huang, Yang Cao, Na Wang, Xiao’ Hong Tan, Ken He Young, Min Xiao, Jian’ Feng Zhou

Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis

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Izhar S. Batth, Qing Meng, Qi Wang, Keila E. Torres, Jared Burks, Jing Wang, Richard Gorlick, Shulin Li

Value of peri-operative chemotherapy in patients with CINSARC high-risk localized grade 1 or 2 soft tissue sarcoma: study protocol of the target selection phase III CHIC-STS trial

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• Study protocol

Thomas Filleron, Sophie Le Guellec, Christine Chevreau, Bastien Cabarrou, Tom Lesluyes, Sabrina Lodin, Angélique Massoubre, Muriel Mounier, Muriel Poublanc, Frédéric Chibon, Thibaud Valentin

Risk adapted approach: How to treat splenic marginal zone lymphoma in resource-poor settings? - The real-life experience of a Brazilian cancer treatment center

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Luís Alberto de Pádua Covas Lage, Felipe Faganelli Caboclo dos Santos, Débora Levy, Frederico Rafael Moreira, Samuel Campanelli Freitas Couto, Hebert Fabrício Culler, Renata de Oliveira Costa, Vanderson Rocha, Juliana Pereira

Evaluation of radioactive 125I seed implantation for the treatment of refractory malignant tumours based on a CT-guided 3D template-assisted technique: efficacy and safety

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Guang Sheng Zhao, Song Liu, Liang Yang, Chuang Li, Ruo Yu Wang, Jun Zhou, Yue Wei Zhang

Risk of second primary malignancy in adults with pulmonary high-grade neuroendocrine carcinoma (HGNEC)

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• Database

Xiaomin Wu, Xiaojing Zhang, Leilei Tao, Ping Chen

Identification of a protein signature for predicting overall survival of hepatocellular carcinoma: a study based on data mining

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Zeng-hong Wu, Dong-liang Yang

Technology-enabled activation of skin cancer screening for hematopoietic cell transplantation survivors and their primary care providers (TEACH)

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Saro H. Armenian, Lanie Lindenfeld, Aleksi Iukuridze, Meagan Echevarria, Samantha Bebel, Catherine Coleman, Ryotaro Nakamura, Farah Abdullah, Badri Modi, Kevin C. Oeffinger, Karen M. Emmons, Ashfaq A. Marghoob, Alan C. Geller

Sexual dysfunction and fertility-related distress in young adults with cancer over 5 years following diagnosis: study protocol of the Fex-Can Cohort study

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• Study protocol

L. Wettergren, L. Ljungman, C. Micaux Obol, L. E. Eriksson, C. Lampic

Clinical impact of PSMA PET/CT in primary prostate cancer compared to conventional nodal and distant staging: a retrospective single center study

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Maarten L. Donswijk, Pim J. van Leeuwen, Erik Vegt, Zing Cheung, Stijn W. T. P. J. Heijmink, Henk G. van der Poel, Marcel P. M. Stokkel

Antagonists of the serotonin receptor 5A target human breast tumor initiating cells

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William D. Gwynne, Mirza S. Shakeel, Adele Girgis-Gabardo, Kwang H. Kim, Emily Ford, Anna Dvorkin-Gheva, Craig Aarts, Methvin Isaac, Rima Al-awar, John A. Hassell

Association of MTHFR C677T polymorphism with severity and localization of chronic atrophic gastritis patients without Helicobacter pylori infection: a case control study

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Siya Kong, Feng Ye, Yini Dang, Yifei Hua, Guoxin Zhang

Smoking cessation and survival among people diagnosed with non-metastatic cancer

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Tracey E. Barnett, Yan Lu, Aaron W. Gehr, Bassam Ghabach, Rohit P. Ojha

Clinical outcomes of immune checkpoint inhibitors for patients with recurrent or metastatic head and neck cancer: real-world data in Korea

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Hyera Kim, Minsuk Kwon, Binnari Kim, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Keunchil Park, Myung-Ju Ahn

Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers

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João Lobo, Ad J. M. Gillis, Annette van den Berg, Leendert H. J. Looijenga

UGT1A1 polymorphism has a prognostic effect in patients with stage IB or II uterine cervical cancer and one or no metastatic pelvic nodes receiving irinotecan chemotherapy: a retrospective study

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Hideki Matsuoka, Ryusuke Murakami, Kaoru Abiko, Ken Yamaguchi, Akihito Horie, Junzo Hamanishi, Tsukasa Baba, Masaki Mandai

A multicenter prospective phase II study of postoperative hypofractionated stereotactic body radiotherapy (SBRT) in the treatment of early-stage oropharyngeal and oral cavity cancers with high risk margins: the STEREO POSTOP GORTEC 2017-03 trial

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• Study protocol

Julian Biau, Emilie Thivat, Corinne Millardet, Nicolas Saroul, Nathalie Pham-Dang, Ioana Molnar, Bruno Pereira, Xavier Durando, Jean Bourhis, Michel Lapeyre

The presence of tumour-infiltrating lymphocytes (TILs) and the ratios between different subsets serve as prognostic factors in advanced hypopharyngeal squamous cell carcinoma

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Jie Wang, Shu Tian, Ji Sun, Jiahao Zhang, Lan Lin, Chunyan Hu

Prognostic value of platelet recovery degree before and after achieving minimal residual disease negative complete remission in acute myeloid leukemia patients

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Yang Wang, Hua Wang, Weida Wang, Wenjian Liu, Nawei Liu, Shuang Liu, Yue Lu

Does hypothyroidism increase the risk of breast cancer: evidence from a meta-analysis

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Bolin Wang, Zhong Lu, Yan Huang, Ruobao Li, Tao Lin

A prospective, single-arm, phase II clinical trial of intraoperative radiotherapy using a low-energy X-ray source for local advanced Laryngocarcinoma (ILAL): a study protocol

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• Study protocol

Yining Yang, Li Li, Yongzhe Zheng, Qingfeng Liu, Xianfeng Wei, Xinyuan Gong, Wei Wang, Peng Lin

A single-center, randomized, non-inferiority study evaluating seroma formation after mastectomy combined with flap fixation with or without suction drainage: protocol for the Seroma reduction and drAin fRee mAstectomy (SARA) trial

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Lisa de Rooij, Sander M. J. van Kuijk, Els R. M. van Haaren, Alfred Janssen, Yvonne L. J. Vissers, Geerard L. Beets, James van Bastelaar

Correction to: Permanent iodine-125 brachytherapy for patients with progressive or recurrent high-grade gliomas

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• Correction

Congxiao Wang, Shifeng Liu, Lijing Peng, Kaixian Zhang, Wei Li, Hao Zhang, Ying Luan, Peishun Li, Xiaokun Hu

Education level as a predictor of survival in patients with multiple myeloma

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Limei Xu, Xiuju Wang, Xueyi Pan, Xiaotao Wang, Qing Wang, Bingyi Wu, Jiahui Cai, Ying Zhao, Lijuan Chen, Wuping Li, Juan Li

The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models

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Julian Ramelow, Christopher D. Brooks, Li Gao, Abeer A. Almiman, Terence M. Williams, Miguel A. Villalona-Calero, Wenrui Duan

Protocol of the VICTORIA study: personalized vitamin D supplementation for reducing or preventing fatigue and enhancing quality of life of patients with colorectal tumor - randomized intervention trial

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Ben Schöttker, Sabine Kuznia, Dana Clarissa Laetsch, David Czock, Annette Kopp-Schneider, Reiner Caspari, Hermann Brenner

OncoPDSS: an evidence-based clinical decision support system for oncology pharmacotherapy at the individual level

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• Software

Quan Xu, Jin-Cheng Zhai, Cai-Qin Huo, Yang Li, Xue-Jiao Dong, Dong-Fang Li, Ru-Dan Huang, Chuang Shen, Yu-Jun Chang, Xi-Ling Zeng, Fan-Lin Meng, Fang Yang, Wan-Ling Zhang, Sheng-Nan Zhang, Yi-Ming Zhou, Zhi Zhang

USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

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Wenjing Diao, Qisang Guo, Caiying Zhu, Yu Song, Hua Feng, Yuankui Cao, Ming Du, Huifen Chen

Prophylactic antibiotic treatment with TMP-SMX decreased the incidence of interstitial pneumonia in patients with B-cell lymphoma on chemotherapy

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Cong Li, Fangxiao Lu, Tao Lei, Haifeng Yu, Xi Chen, Shuailing Peng, Shuiyun Han, Haiyan Yang

Immunotherapy and associated immune-related adverse events at a large UK centre: a mixed methods study

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Liz Jamieson, Martin D. Forster, Kam Zaki, Sanjena Mithra, Heena Alli, Anne O’Connor, Apini Patel, Ian C. K. Wong, Pinkie Chambers

Diagnostic accuracy of contrast-enhanced diffusion-weighted MRI for liver metastases of pancreatic cancer: towards adequate staging and follow-up of pancreatic cancer – DIA-PANC study: study protocol for an international, multicenter, diagnostic trial

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G. Litjens, D. M. Rivière, E. J. M. van Geenen, S. A. Radema, L. A. A. Brosens, M. Prokop, C. J. H. M. van Laarhoven, J. J. Hermans

Androgen Receptor mRNA levels determine the prognosis in triple-negative breast cancer patients

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Sindhu Govindan, Mallikarjuna Siraganahalli Eswaraiah, Chetana Basavaraj, Manjula Adinarayan, Satish Sankaran, Manjiri Bakre

Prognosis of pregnancy-associated breast cancer: a meta-analysis

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Chunchun Shao, Zhigang Yu, Juan Xiao, Liyuan Liu, Fanzhen Hong, Yuan Zhang, Hongying Jia

Screening of BRCA1/2 genes mutations and copy number variations in patients with high risk for hereditary breast and ovarian cancer syndrome (HBOC)

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Fatima Zahra El Ansari, Farah Jouali, Nabila Marchoudi, Mohcine Mechita Bennani, Naima Nourouti Ghailani, Amina Barakat, Jamal Fekkak

Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment

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Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Aurélie Bertaut, Emilie Rederstorff, Francois Ghiringhelli

LINC00992 contributes to the oncogenic phenotypes in prostate cancer via targeting miR-3935 and augmenting GOLM1 expression

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Jianheng Chen, Xiaodong Liu, Kunbin Ke, Jianan Zou, Zhan Gao, Tomonori Habuchi, Xuezhen Yang

Neutrophil to lymphocyte ratio, not platelet to lymphocyte or lymphocyte to monocyte ratio, is predictive of patient survival after resection of early-stage pancreatic ductal adenocarcinoma

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David T. Pointer Jr., David Roife, Benjamin D. Powers, Gilbert Murimwa, Sameh Elessawy, Zachary J. Thompson, Michael J. Schell, Pamela J. Hodul, Jose M. Pimiento, Jason B. Fleming, Mokenge P. Malafa

Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

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Zaid H. Maayah, Shingo Takahara, Abrar S. Alam, Mourad Ferdaoussi, Gopinath Sutendra, Ayman O. S. El-Kadi, John R. Mackey, Edith Pituskin, D. Ian Paterson, Jason R. B. Dyck

Premature mortality of gastrointestinal cancer in Iran: trends and projections 2001–2030

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Fatemeh Khosravi Shadmani, Farshad Farzadfar, Moein Yoosefi, Kamyar Mansori, Reza Khosravi Shadman, Aliakbar Haghdoost

Increasing of malignancy of breast cancer cells after cryopreservation: molecular detection and activation of angiogenesis after CAM-xenotransplantation

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Xinxin Du, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Peter Mallmann, Yuanguang Meng, Vladimir Isachenko

When to call it off: defining transplant candidacy limits in liver donor liver transplantation for hepatocellular carcinoma

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Abu Bakar Hafeez Bhatti, Ammal Imran Qureshi, Rizmi Tahir, Faisal Saud Dar, Nusrat Yar Khan, Haseeb Haider Zia, Shahzad Riyaz, Atif Rana

Adjuvant chemotherapy in average-risk adult medulloblastoma patients improves survival: a long term study

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E. Franceschi, S. Minichillo, A. Mura, A. Tosoni, M. Mascarin, C. Tomasello, S. Bartolini, A. A. Brandes

Tumor expression of miR-448 is a prognostic marker in oral squamous cell carcinoma

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Hui Wei, Kang Yu, Yongheng Liu, Lili Li, Guowen Wang

Impact on quality of life 3 years after diagnosis of prostate cancer patients below 75 at diagnosis: an observational case-control study

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Nadine Houédé, Xavier Rébillard, Sophie Bouvet, Sarah Kabani, Pascale Fabbro-Peray, Brigitte Trétarre, Florence Ménégaux

Quality of life and psychological distress during cancer: a prospective observational study involving young breast cancer female patients

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Barbara Muzzatti, Francesca Bomben, Cristiana Flaiban, Marika Piccinin, Maria Antonietta Annunziata

Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

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Cristina Sarasqueta, Mª Victoria Zunzunegui, José María Enríquez Navascues, Arrate Querejeta, Carlos Placer, Amaia Perales, Nerea Gonzalez, Urko Aguirre, Marisa Baré, Antonio Escobar, José María Quintana, Jose María Quintana López, Marisa Baré Mañas, Maximino Redondo Bautista, Eduardo Briones Pérez de la Blanca, Nerea Fernández de Larrea Baz, Cristina Sarasqueta Eizaguirre, Antonio Escobar Martínez, Francisco Rivas Ruiz, Maria M. Morales-Suárez-Varela, Juan Antonio Blasco Amaro, Isabel del Cura González, Inmaculada Arostegui Madariaga, Amaia Bilbao González, Nerea González Hernández, Susana García-Gutiérrez, Iratxe Lafuente Guerrero, Urko Aguirre Larracoechea, Miren Orive Calzada, Josune Martin Corral, Ane Antón-Ladislao, Núria Torà, Marina Pont, María Purificación Martínez del Prado, Alberto Loizate Totorikaguena, Ignacio Zabalza Estévez, José Errasti Alustiza, Antonio Z. Gimeno García, Santiago Lázaro Aramburu, Mercè Comas Serrano, Jose María Enríquez Navascues, Carlos Placer Galán, Amaia Perales Antón, Iñaki Urkidi Valmaña, Jose María Erro Azkárate, Enrique Cormenzana Lizarribar, Adelaida Lacasta Muñoa, Pep Piera Pibernat, Elena Campano Cuevas, Ana Isabel Sotelo Gómez, Segundo Gómez-Abril, F. Medina-Cano, Julia Alcaide, Arturo Del Rey-Moreno, Manuel Jesús Alcántara, Rafael Campo, Alex Casalots, Carles Pericay, Maria José Gil, Miquel Pera, Pablo Collera, Josep Alfons Espinàs, Mercedes Martínez, Mireia Espallargues, Caridad Almazán, Paula Dujovne Lindenbaum, José María Fernández-Cebrián, Rocío Anula Fernández, Julio Mayol Martínez, Ramón Cantero Cid, Héctor Guadalajara Labajo, María Alexandra Heras Garceau, Damián García Olmo, Mariel Morey Montalvo

Safety and efficacy of sintilimab combined with oxaliplatin/capecitabine as first-line treatment in patients with locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma in a phase Ib clinical trial

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Haiping Jiang, Yulong Zheng, Jiong Qian, Chenyu Mao, Xin Xu, Ning Li, Cheng Xiao, Huan Wang, Lisong Teng, Hui Zhou, Shuyan Wang, Donglei Zhu, Bo Peng, Lin Shen, Nong Xu

Influence of tumor location on short- and long-term outcomes after laparoscopic surgery for rectal cancer: a propensity score matched cohort study

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Hong Yang, Zhendan Yao, Ming Cui, Jiadi Xing, Chenghai Zhang, Nan Zhang, Maoxing Liu, Kai Xu, Fei Tan, Xiangqian Su

Log odds of positive lymph nodes is prognostically equivalent to lymph node ratio in non-metastatic colon cancer

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Ali Riaz Baqar, Simon Wilkins, Wei Wang, Karen Oliva, Paul McMurrick

Value of artificial ascites to assist thermal ablation of liver cancer adjacent to the gastrointestinal tract in patients with previous abdominal surgery

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Qiannan Huang, Jianguo Li, Qingjing Zeng, Lei Tan, Rongqin Zheng, Xuqi He, Kai Li

Ipilimumab plus nivolumab and chemoradiotherapy followed by surgery in patients with resectable and borderline resectable T3-4N0–1 non-small cell lung cancer: the INCREASE trial

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• Study protocol

Chris Dickhoff, Suresh Senan, Famke L. Schneiders, Joris Veltman, Sayed Hashemi, Johannes M. A. Daniels, Marieke Fransen, David J. Heineman, Teodora Radonic, Peter M. van de Ven, Imke H. Bartelink, Lilian J. Meijboom, Juan J. Garcia-Vallejo, Daniela E. Oprea-Lager, Tanja D. de Gruijl, Idris Bahce

Tumor burden of persistent disease in patients with differentiated thyroid cancer: correlation with postoperative risk-stratification and impact on outcome

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Renaud Ciappuccini, Natacha Heutte, Audrey Lasne-Cardon, Virginie Saguet-Rysanek, Camille Leroy, Véronique Le Hénaff, Dominique Vaur, Emmanuel Babin, Stéphane Bardet

Prognostic value of S1PR1 and its correlation with immune infiltrates in breast and lung cancers

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Limei Zhong, Linling Xie, Zhiyong Yang, Lijuan Li, Shaohua Song, Donglin Cao, Yufeng Liu

Quantified MRI and 25OH-VitD3 can be used as effective biomarkers for patients with neoadjuvant chemotherapy-induced liver injury in CRCLM?

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Qian Wang, Feng Ye, Peiqing Ma, Yiqun Che, Weilan Guo, Dong Yan, Xinming Zhao

Supporting the patients with advanced cancer and their family caregivers: what are their palliative care needs?

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Gek Phin Chua, Grace Su Yin Pang, Alethlea Chung Pheng Yee, Patricia Soek Hui Neo, Siqin Zhou, Cindy Lim, Yin Yee Wong, Debra Limin Qu, Fang Ting Pan, Grace Meijuan Yang

Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases

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Na Li, Jinhai Gou, Lin Li, Xiu Ming, Ting Wenyi Hu, Zhengyu Li

The efficacy of a leukotriene receptor antagonist in the treatment of human rectal aberrant crypt foci: a nonrandomized, open-label, controlled trial

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Takuma Higurashi, Jun Arimoto, Keiichi Ashikari, Tomohiro Takatsu, Noboru Misawa, Tsutomu Yoshihara, Tetsuya Matsuura, Akiko Fuyuki, Hidenori Ohkubo, Atsushi Nakajima

Identification of an autophagy-related gene signature that can improve prognosis of hepatocellular carcinoma patients

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Xingxing Huo, Jian Qi, Kaiquan Huang, Su Bu, Wei Yao, Ying Chen, Jinfu Nie

Identifying predictive biomarkers of CIMAvaxEGF success in non–small cell lung cancer patients

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Patricia Lorenzo-Luaces, Lizet Sanchez, Danay Saavedra, Tania Crombet, Wim Van der Elst, Ariel Alonso, Geert Molenberghs, Agustin Lage

An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types

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Wai Hoong Chang, Alvina G. Lai

Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

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Md Gulam Musawwir Khan, Amit Ghosh, Bhavesh Variya, Madanraj Appiya Santharam, Awais Ullah Ihsan, Sheela Ramanathan, Subburaj Ilangumaran

PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

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Verena Weigert, Tina Jost, Markus Hecht, Ilka Knippertz, Lucie Heinzerling, Rainer Fietkau, Luitpold V. Distel

Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study

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• Study protocol

I. van den Berg, S. van de Weerd, J. M. L. Roodhart, G. R. Vink, R. R. J. Coebergh van den Braak, C. R. Jimenez, S. G. Elias, D. van Vliet, M. Koelink, E. Hong, W. M. U. van Grevenstein, M. G. H. van Oijen, R. G. H. Beets-Tan, J. H. J. M. van Krieken, J. N. M. IJzermans, J. P. Medema, M. Koopman

Comparison of overall survival of gastric neoplasms containing neuroendocrine carcinoma components with gastric adenocarcinoma: a propensity score matching study

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Jiahui Chen, Anqiang Wang, Ke Ji, Zhaode Bu, Jiafu Ji

Survival predictors of metastatic angiosarcomas: a surveillance, epidemiology, and end results program population-based retrospective study

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Shihong Ren, Yucheng Wang, Zhan Wang, Jinxiang Shao, Zhaoming Ye

Long-term sexual functioning in germ-cell tumor survivors

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M. Chovanec, L. Vasilkova, L. Petrikova, J. Obertova, P. Palacka, K. Rejlekova, Z. Sycova-Mila, K. Kalavska, D. Svetlovska, B. Mladosievicova, J. Mardiak, M. Mego

Long term outcome of anastomotic leakage in patients undergoing low anterior resection for rectal cancer

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Alice Artus, Nicolas Tabchouri, Othman Iskander, Nicolas Michot, Olivier Muller, Urs Giger-Pabst, Pascal Bourlier, Céline Bourbao-Tournois, Aurore Kraemer-Bucur, Thierry Lecomte, Ephrem Salamé, Mehdi Ouaissi

The CARDIA-trial protocol: a multinational, prospective, randomized, clinical trial comparing transthoracic esophagectomy with transhiatal extended gastrectomy in adenocarcinoma of the gastroesophageal junction (GEJ) type II

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• Study protocol

Jessica M. Leers, Laura Knepper, Arjen van der Veen, Wolfgang Schröder, Hans Fuchs, Petra Schiller, Martin Hellmich, Ulrike Zettelmeyer, Lodewijk A. A. Brosens, Alexander Quaas, Jelle P. Ruurda, Richard van Hillegersberg, Christiane J. Bruns

A ten-gene signature-based risk assessment model predicts the prognosis of lung adenocarcinoma

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Hanliang Jiang, Shan Xu, Chunhua Chen

Randomized double-blind clinical trial comparing safety and efficacy of the biosimilar BCD-022 with reference trastuzumab

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Sergey M. Alexeev, Andrey V. Khorinko, Guzel Z. Mukhametshina, Konstantin G. Shelepen, Olga N. Burdaeva, Sergey A. Kulik, Chiradoni Thugappa Satheesh, Kirti Srivastava, Mummaneni Vikranth, Fedor Kryukov, Anastasia N. Paltusova, Mariya S. Shustova, Roman A. Ivanov

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

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Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux

Pneumonitis after radiotherapy for lung cancer (PARALUC): an interventional study to create a symptom-based scoring system for identification of patients developing radiation pneumonitis

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Dirk Rades, Elisa Marie Werner, Esther Glatzel, Marie-Christine Eggert, Denise Olbrich, Soeren Tvilsted, Sabine Bohnet

Height as a risk factor in meningioma: a study of 2 million Israeli adolescents

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Matan Ben-Zion Berliner, Lior Haim Katz, Estela Derazne, Hagai Levine, Lital Keinan-Boker, Alexandra Benouaich-Amiel, Omer Gal, Andrew A Kanner, Yosef Laviv, Asaf Honig, Tali Siegal, Jacob Mandel, Gilad Twig, Shlomit Yust-Katz

The impact of high-intensity interval training exercise on breast cancer survivors: a pilot study to explore fitness, cardiac regulation and biomarkers of the stress systems

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Kellie Toohey, Kate Pumpa, Andrew McKune, Julie Cooke, Marijke Welvaert, Joseph Northey, Clare Quinlan, Stuart Semple

Association between adipokines and thyroid carcinoma: a meta-analysis of case-control studies

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Junyu Zhao, Jing Wen, Shengnan Wang, Jinming Yao, Lin Liao, Jianjun Dong

MEIS1 promotes expression of stem cell markers in esophageal squamous cell carcinoma

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Selma Zargari, Shabnam Negahban Khameneh, Abolfazl Rad, Mohammad Mahdi Forghanifard

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study

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S. J. Schraa, K. L. van Rooijen, D. E. W. van der Kruijssen, C. Rubio Alarcón, J. Phallen, M. Sausen, J. Simmons, V. M. H. Coupé, W. M. U. van Grevenstein, S. Elias, H. M. Verkooijen, M. M. Laclé, L. J. W. Bosch, D. van den Broek, G. A. Meijer, V. E. Velculescu, R. J. A. Fijneman, G. R. Vink, M. Koopman, Mich S. Dunker, Martijn F. Lutke Holzik, Ronald Hoekstra, Dirkje W. Sommeijer, Jarmila D. W. van der Bilt, Esther C. J. Consten, Geert A. Cirkel, Thijs A. Burghgraef, Emma M. van der Schans, Peter Nieboer, Ron C. Rietbroek, Jan Willem T. Dekker, Arjan J. Verschoor, Koen A. K. Talsma, Rebecca P. M. Brosens, Helgi H. Helgason, Andreas W. K. S. Marinelli, Ignace H. J. T. de Hingh, Corina N. Oldenhuis, Jan Jansen, Henk K. van Halteren, Hein B. A. C. Stockmann, Aart Beeker, Koop Bosscha, Hans F. M. Pruijt, Leontine E. A. M. M. Spierings, Liselot B. J. Valkenburg-Van Iersel, Wouter J. Vles, Felix E. de Jongh, Hester van Cruijsen, Joost T. Heikens, David D. E. Zimmerman, Robert J. van Alphen, Anandi H. W. Schiphorst, Lobke L. van Leeuwen-Snoeks, Jeroen F. J. Vogelaar, Natascha A. J. B. Peters

Clinical effects of curcumin in enhancing cancer therapy: A systematic review

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Kamran Mansouri, Shna Rasoulpoor, Alireza Daneshkhah, Soroush Abolfathi, Nader Salari, Masoud Mohammadi, Shabnam Rasoulpoor, Shervin Shabani

Effectiveness of the AJCC 8th edition staging system for selecting patients with T1–2N1 breast cancer for post-mastectomy radiotherapy: a joint analysis of 1986 patients from two institutions

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Shulian Wang, Ge Wen, Yu Tang, Yong Yang, Hao Jing, Jianyang Wang, Jianghu Zhang, Xuran Zhao, Guangyi Sun, Jing Jin, Yongwen Song, Yueping Liu, Hui Fang, Yujing Zhang, Yexiong Li

Nomogram model for predicting cause-specific mortality in patients with stage I small-cell lung cancer: a competing risk analysis

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Jianjie Li, Qiwen Zheng, Xinghui Zhao, Jun Zhao, Tongtong An, Meina Wu, Yuyan Wang, Minglei Zhuo, Jia Zhong, Xue Yang, Bo Jia, Hanxiao Chen, Zhi Dong, Jingjing Wang, Yujia Chi, Xiaoyu Zhai, Ziping Wang

OTX1 exerts an oncogenic role and is negatively regulated by miR129-5p in laryngeal squamous cell carcinoma

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Xiu-Ping Tu, Hao Li, Liang-Si Chen, Xiao-Ning Luo, Zhong-Ming Lu, Si-Yi Zhang, Shao-Hua Chen

Monitoring and evaluation of breast cancer screening programmes: selecting candidate performance indicators

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Sergei Muratov, Carlos Canelo-Aybar, Jean-Eric Tarride, Pablo Alonso-Coello, Nadya Dimitrova, Bettina Borisch, Xavier Castells, Stephen W. Duffy, Patricia Fitzpatrick, Markus Follmann, Livia Giordano, Solveig Hofvind, Annette Lebeau, Cecily Quinn, Alberto Torresin, Claudia Vialli, Sabine Siesling, Antonio Ponti, Paolo Giorgi Rossi, Holger Schünemann, Lennarth Nyström, Mireille Broeders, Mariangela Autelitano, Edoardo Colzani, Jan Daneš, Axel Gräwingholt, Lydia Ioannidou-Mouzaka, Susan Knox, Miranda Langendam, Helen McGarrigle, Elsa Pérez Gómez, Ruben van Engen, Sue Warman, Kenneth Young, Cary van Landsveld-Verhoeven, Donata Lerda, Zuleika Saz-Parkinson, Elena Parmelli, Annett Janusch-Roi

HPV infection related immune infiltration gene associated therapeutic strategy and clinical outcome in HNSCC

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Hao Zeng, Xindi Song, Jianrui Ji, Linyan Chen, Qimeng Liao, Xuelei Ma

Prognostic significance of autophagy-related genes within esophageal carcinoma

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Chongxiang Chen, Siliang Chen, Huijiao Cao, Jiaojiao Wang, Tianmeng Wen, Xiaochun Hu, Huan Li

Outcomes of treatment with CHOP and EPOCH in patients with HIV associated NHL in a low resource setting

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Clement D. Okello, Abrahams Omoding, Henry Ddungu, Yusuf Mulumba, Jackson Orem

Differentiating the lung lesions using Intravoxel incoherent motion diffusion-weighted imaging: a meta-analysis

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Jianye Liang, Jing Li, Zhipeng Li, Tiebao Meng, Jieting Chen, Weimei Ma, Shen Chen, Xie Li, Yaopan Wu, Ni He

Sphingomyelin(d35:1) as a novel predictor for lung adenocarcinoma recurrence after a radical surgery: a case-control study

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Yusuke Takanashi, Kazuhito Funai, Shumpei Sato, Akikazu Kawase, Hong Tao, Yutaka Takahashi, Haruhiko Sugimura, Mitsutoshi Setou, Tomoaki Kahyo, Norihiko Shiiya

Protocol for expanded indications of endoscopic submucosal dissection for early gastric cancer in China: a multicenter, ambispective, observational, open-cohort study

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Zhi Zheng, Jie Yin, Ziyu Li, Yingjiang Ye, Bo Wei, Xin Wang, Yantao Tian, Mengyi Li, Qian Zhang, Na Zeng, Rui Xu, Guangyong Chen, Jie Zhang, Peng Li, Jun Cai, Hongwei Yao, Jun Zhang, Zhongtao Zhang, Shutian Zhang

Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells

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Ko Igarashi, Yoshihiro Yui, Kenta Watanabe, Jun Kumai, Yasuko Nishizawa, Chisato Miyaura, Masaki Inada, Satoru Sasagawa

Endothelial activation and stress index (EASIX) is a reliable predictor for overall survival in patients with multiple myeloma

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Ga-Young Song, Sung-Hoon Jung, Kihyun Kim, Seok Jin Kim, Sang Eun Yoon, Ho Sup Lee, Mihee Kim, Seo-Yeon Ahn, Jae-Sook Ahn, Deok-Hwan Yang, Hyeoung-Joon Kim, Je-Jung Lee

Post-diagnostic antipsychotic use and cancer mortality: a population based cohort study

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Blánaid M. Hicks, John Busby, Ken Mills, Francis A. O’Neil, Stuart A. McIntosh, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R. Cardwell

The CanMoRe trial – evaluating the effects of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer: the study protocol of a randomised controlled trial

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Andrea Porserud, Patrik Karlsson, Elisabeth Rydwik, Markus Aly, Lars Henningsohn, Malin Nygren-Bonnier, Maria Hagströmer

Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial

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Farastuk Bozorgmehr, Inn Chung, Petros Christopoulos, Johannes Krisam, Marc A. Schneider, Lena Brückner, Daniel Wilhelm Mueller, Michael Thomas, Stefan Rieken

Is opium use associated with an increased risk of lung cancer? A case-control study

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Ahmad Naghibzadeh-Tahami, Maryam Marzban, Vahid Yazdi-Feyzabadi, Shahryar Dabiri, Shokrollah Mohseni, Reza Abbasi Rayeni, Mitra Samareh Fekri, Mohammad Hasan Larizadeh, Behnaz Karimpour, Narges Khanjani

Effectiveness of intravitreal chemotherapy-assisted endoresection in monocular patients with group D retinoblastoma

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Xiling Yu, Xueke Li, Yue Xing, Siduo Lu, Silvia Tanumiharjo, Jin Ma

The impact of order with radiation therapy in stage IIIA pathologic N2 NSCLC patients: a population-based study

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Hongxia Duan, Long Liang, Shuanshuan Xie, Changhui Wang

Outcomes of prior cervical cytology and HR-HPV testing in women subsequently diagnosed with CIN1, CIN2/3, and invasive cervical cancer: a 4-year routine clinical experience after implementation of systematic training and quality control programs

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Dongman Zhao, Liran Zhang, Fengxiang Xie, Dezhi Peng, Jie Wei, Lingbo Jiang, Shoudu Zhang, Debo Qi

Epidemiological features and survival outcomes in patients with malignant pulmonary blastoma: a US population-based analysis

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Xiang Bu, Jing Liu, Linyan Wei, Xiqiang Wang, Mingwei Chen

Effect of microwave ablation treatment of hepatic malignancies on serum cytokine levels

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Jing Zhao, Qiang Li, Merlin Muktiali, Bingjie Ren, Yingxi Hu, Dapeng Li, Zhi Li, Daoming Li, Yufeng Xie, Min Tao, Rongrui Liang

Treatment strategy and outcomes in locally advanced head and neck squamous cell carcinoma: a nationwide retrospective cohort study (KCSG HN13–01)

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Yun-Gyoo Lee, Eun Joo Kang, Bhumsuk Keam, Jin-Hyuk Choi, Jin-Soo Kim, Keon Uk Park, Kyoung Eun Lee, Jung Hye Kwon, Keun-Wook Lee, Min Kyoung Kim, Hee Kyung Ahn, Seong Hoon Shin, Hye Ryun Kim, Sung-Bae Kim, Hwan Jung Yun

Comprehensive analysis of prognostic tumor microenvironment-related genes in osteosarcoma patients

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Chuan Hu, Chuan Liu, Shaoqi Tian, Yuanhe Wang, Rui Shen, Huili Rao, Jianyi Li, Xu Yang, Bo Chen, Lin Ye

Tissue mechanics and expression of TROP2 in oral squamous cell carcinoma with varying differentiation

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Baoping Zhang, Shuting Gao, Ruiping Li, Yiting Li, Rui Cao, Jingyang Cheng, Yumeng Guo, Errui Wang, Ying Huang, Kailiang Zhang

DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation

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Xuemin Xue, Wenting Huang, Tian Qiu, Lei Guo, Jianming Ying, Ning Lv

Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma

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Dieter H. Heiland, Robin Ohle, Debora Cipriani, Pamela Franco, Daniel Delev, Simon P. Behriger, Elias Kellner, Gergana Petrova, Nicolas Neidert, Irina Mader, Mateo Fariña Nuñez, Horst Urbach, Roman Sankowski, Jürgen Beck, Oliver Schnell

Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients

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Fred K. Tabung, Anne Noonan, Dong Hoon Lee, Mingyang Song, Steven K. Clinton, Daniel Spakowicz, Kana Wu, En Cheng, Jeffrey A. Meyerhardt, Charles S. Fuchs, Edward L. Giovannucci

Parental occupational exposure to pesticides and risk of childhood cancer in Switzerland: a census-based cohort study

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Astrid Coste, Helen D. Bailey, Mutlu Kartal-Kaess, Raffaele Renella, Aurélie Berthet, Ben D. Spycher

A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer

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Clinton L. Cario, Emmalyn Chen, Lancelote Leong, Nima C. Emami, Karen Lopez, Imelda Tenggara, Jeffry P. Simko, Terence W. Friedlander, Patricia S. Li, Pamela L. Paris, Peter R. Carroll, John S. Witte

Interleukin-8 is not a predictive biomarker for the development of the acute promyelocytic leukemia differentiation syndrome

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Luciana Yamamoto de Almeida, Diego Antonio Pereira-Martins, Ana Sílvia Gouvêa Lima, Márcia Sueli Baggio, Luisa Corrêa de Araujo Koury, Ana Paula Lange, Sarah Cristina Bassi, Priscila Santos Scheucher, Eduardo Magalhães Rego

Phase II study on first-line treatment of NIVolumab in combination with folfoxiri/bevacizumab in patients with Advanced COloRectal cancer RAS or BRAF mutated – NIVACOR trial (GOIRC-03-2018)

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Angela Damato, Francesco Iachetta, Lorenzo Antonuzzo, Guglielmo Nasti, Francesca Bergamo, Roberto Bordonaro, Evaristo Maiello, Alberto Zaniboni, Giuseppe Tonini, Alessandra Romagnani, Annalisa Berselli, Nicola Normanno, Carmine Pinto

Clinical benefit of immune checkpoint inhibitors approved by US Food and Drug Administration

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Fei Liang, Sheng Zhang, Qin Wang, Wenfeng Li

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target

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Kumar Saurabh, Parag P. Shah, Mark A. Doll, Leah J. Siskind, Levi J. Beverly

Pro-cathepsin D as a diagnostic marker in differentiating malignant from benign pleural effusion: a retrospective cohort study

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Hayoung Choi, Yousang Ko, Chang Youl Lee

Raised CA19–9 and CEA have prognostic relevance in gallbladder carcinoma

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Ashish Sachan, Sundeep Singh Saluja, Phani Kumar Nekarakanti, Nimisha, Bhawna Mahajan, Hirdaya H. Nag, Pramod K. Mishra

Prophylactic chemotherapeutic hyperthermic intraperitoneal perfusion reduces peritoneal metastasis in gastric cancer: a retrospective clinical study

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Lucheng Zhu, Zhizheng Xu, Yajun Wu, Pengyuan Liu, Jianing Qian, Shuhuan Yu, Bing Xia, Jianjun Lai, Shenglin Ma, Zhibing Wu

A predictive nomogram for lymph node metastasis of incidental gallbladder cancer: a SEER population-based study

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Yingnan Yang, Zhuolong Tu, Huajie Cai, Bingren Hu, Chentao Ye, Jinfu Tu

Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations

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Oscar Arrieta, Rodrigo Catalán, Silvia Guzmán-Vazquez, Feliciano Barrón, Luis Lara-Mejía, Herman Soto-Molina, Maritza Ramos-Ramírez, Diana Flores-Estrada, Jaime de la Garza

Racial differences in 5-year relative survival rates of cervical cancer by stage at diagnosis, between African American (black) and white women, living in the state of Alabama, USA

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Ehsan Abdalla, Roberta Troy, Souleymane Fall, Isra Elhussin, Oyoyo Egiebor-Aiwan, David Nganwa

Short-course radiation followed by mFOLFOX-6 plus avelumab for locally-advanced rectal adenocarcinoma

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Ali Shamseddine, Youssef H. Zeidan, Malek Kreidieh, Ibrahim Khalifeh, Rim Turfa, Joseph Kattan, Deborah Mukherji, Sally Temraz, Kholoud Alqasem, Rula Amarin, Tala Al Awabdeh, Samer Deeba, Faek Jamali, Issa Mohamad, Mousa Elkhaldi, Faiez Daoud, Mahmoud Al Masri, Ali Dabous, Ahmad Hushki, Omar Jaber, Clement Khoury, Ziad El Husseini, Maya Charafeddine, Monita Al Darazi, Fady Geara

Dose-dense TPF induction chemotherapy for locally advanced head and neck cancer: a phase II study

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Ching-Yun Hsieh, Ming-Yuh Lein, Shih-Neng Yang, Yao-Ching Wang, Yin-Jun Lin, Chen-Yuan Lin, Chun-Hung Hua, Ming-Hsul Tsai, Ching-Chan Lin

Calculating the overall survival probability in patients with cervical cancer: a nomogram and decision curve analysis-based study

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Guilan Xie, Ruiqi Wang, Li Shang, Cuifang Qi, Liren Yang, Liyan Huang, Wenfang Yang, Mei Chun Chung

Correction to: A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

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Khayal Al-Khayal, Mansoor-Ali Vaali-Mohammed, Mohammed Elwatidy, Thamer Bin Traiki, Omar Al-Obeed, Mohammad Azam, Zahid Khan, Maha Abdulla, Rehan Ahmad

Alteration of plasma metabolites associated with chemoradiosensitivity in esophageal squamous cell carcinoma via untargeted metabolomics approach

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Yaowen Zhang, Jianpo Wang, Ningtao Dai, Peng Han, Jian Li, Jiangman Zhao, Weilan Yuan, Jiahuan Zhou, Fuyou Zhou

The efficacy of etanercept as anti-breast cancer treatment is attenuated by residing macrophages

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Elnaz Shirmohammadi, Seyed-Esmaeil Sadat Ebrahimi, Amir Farshchi, Mona Salimi

Prognostic analysis of patients with non-small cell lung cancer harboring exon 19 or 21 mutation in the epidermal growth factor gene and brain metastases

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Jing Wang, Zhiyan Liu, Qingsong Pang, Tian Zhang, Xi Chen, Puchun Er, Yuwen Wang, Ping Wang, Jun Wang

Long non-coding RNA SNHG3 promotes breast cancer cell proliferation and metastasis by binding to microRNA-154-3p and activating the notch signaling pathway

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Hongnan Jiang, Xiaojun Li, Wei Wang, Honglin Dong

SNHG17 drives malignant behaviors in astrocytoma by targeting miR-876-5p/ERLIN2 axis

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Fengping Du, Qian Hou

WDHD1 facilitates G1 checkpoint abrogation in HPV E7 expressing cells by modulating GCN5

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Yunying Zhou, Fengyan Pei, Mingyu Ji, Fang Zhang, Yingshuo Sun, Qianqian Zhao, Xiao Wang, Yatian Hong, Juanjuan Tian, Yunshan Wang, Jason J. Chen

LINC00649 underexpression is an adverse prognostic marker in acute myeloid leukemia

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Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li

Myxoid stroma is associated with postoperative relapse in patients with stage II colon cancer

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Takashi Okuyama, Shinichi Sameshima, Emiko Takeshita, Takashi Mitsui, Takuji Noro, Yuko Ono, Tamaki Noie, Shinichi Ban, Masatoshi Oya

Cell-in-cell phenomenon associates with aggressive characteristics and cancer-related mortality in early oral tongue cancer

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Alhadi Almangush, Antti A. Mäkitie, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Pentti Nieminen, Ricardo D. Coletta, Tuula Salo, Ilmo Leivo

Metastatic renal cell carcinoma patients of T4 stage who are in status of N1 stage or older than 76 years cannot benefit from cytoreductive nephrectomy

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Zhao Zhang, Hongliang Wu, Tong Yang, Yaohai Wu, Nengwang Yu, Zhonghua Xu

Promotion of the occurrence of endometrioid carcinoma by S100 calcium binding protein P

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Dan Zhang, Xiuying Chen, Hexia Xia, Lu Wang, Hongbo Zhao, Bufang Xu, Aijun Zhang, Wei Zhang

Lifetime survival and medical costs of lung cancer: a semi-parametric estimation from South Korea

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Hae-Young Park, Jinseub Hwang, Do-Hyang Kim, Soo Min Jeon, Sun Ha Choi, Jin-Won Kwon

Patient and physician factors associated with Oncotype DX and adjuvant chemotherapy utilization for breast cancer patients in New Hampshire, 2010–2016

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Thomas M. Schwedhelm, Judy R. Rees, Tracy Onega, Ronnie J. Zipkin, Andrew Schaefer, Maria O. Celaya, Erika L. Moen

Impact of smoking amount on clinicopathological features and survival in non-small cell lung cancer

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Woo Ho Ban, Chang Dong Yeo, Solji Han, Hye Seon Kang, Chan Kwon Park, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee, Sung Kyoung Kim

Survival analysis of patients with stage T2a and T2b perihilar cholangiocarcinoma treated with radical resection

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Jian Zhao, Wei Zhang, Jun Zhang, Yi Zhang, Wen-Jie Ma, Si-Yun Liu, Fu-Yu Li, Bin Song

Interconnectivity between molecular subtypes and tumor stage in colorectal cancer

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R. R. J. Coebergh van den Braak, S. ten Hoorn, A. M. Sieuwerts, J. B. Tuynman, M. Smid, S. M. Wilting, J. W. M. Martens, C. J. A. Punt, J. A. Foekens, J. P. Medema, J. N. M. IJzermans, L. Vermeulen

Young age increases the risk of lymph-node metastasis in patients with muscle-invasive bladder urothelial carcinoma

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Zijian Tian, Lingfeng Meng, Xin Wang, Tongxiang Diao, Maolin Hu, Miao Wang, Ming Liu, Jianye Wang

WeChat app-based reinforced education improves the quality of opioid titration treatment of cancer-related pain in outpatients: a randomized control study

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Zhiyou Peng, Lin Li, Yuan Chen, Zhiying Feng, Xiangming Fang

ERCC6L promotes the progression of hepatocellular carcinoma through activating PI3K/AKT and NF-κB signaling pathway

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Han Chen, Hengxiao Wang, Xiqiao Yu, Shuping Zhou, Yueying Zhang, Zhaopeng Wang, Shuhong Huang, Zhaoxia Wang

Worse treatment response to neoadjuvant chemoradiotherapy in young patients with locally advanced rectal cancer

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Yiyi Zhang, Liangliang Yan, Yong Wu, Meifang Xu, Xing Liu, Guoxian Guan

Real-world patient-reported outcomes of women receiving initial endocrine-based therapy for HR+/HER2− advanced breast cancer in five European countries

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Alison Davie, Gebra Cuyun Carter, Alex Rider, James Pike, Katie Lewis, Abigail Bailey, Gregory L. Price, Francois Ringeisen, Xavier Pivot

Bayesian copy number detection and association in large-scale studies

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Stephen Cristiano, David McKean, Jacob Carey, Paige Bracci, Paul Brennan, Michael Chou, Mengmeng Du, Steven Gallinger, Michael G. Goggins, Manal M. Hassan, Rayjean J. Hung, Robert C. Kurtz, Donghui Li, Lingeng Lu, Rachel Neale, Sara Olson, Gloria Petersen, Kari G. Rabe, Jack Fu, Harvey Risch, Gary L. Rosner, Ingo Ruczinski, Alison P. Klein, Robert B. Scharpf

Identification of a novel subgroup of endometrial cancer patients with loss of thyroid hormone receptor beta expression and improved survival

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Daniel G. Piqué, John M. Greally, Jessica C. Mar

Magnitude and associated factors of VIA positive test results for cervical cancer screening among refugee women aged 25–49 years in North Ethiopia

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Gebretsadik Hailemariam, Hailay Gebreyesus, Tewolde Wubayehu, Tsgehana Gebregyorgis, Kidanemariam Gebrecherkos, Mebrahtu Teweldemedhin, Manaye Kifle

Contribution of BRCA1 and BRCA2 germline mutations to early onset breast cancer: a series from north of Morocco

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Joaira Bakkach, Mohamed Mansouri, Touria Derkaoui, Ali Loudiyi, ElMostafa El Fahime, Amina Barakat, Naima Ghailani Nourouti, Jaime Martinez De Villarreal, Carlos Cortijo Bringas, Mohcine Bennani Mechita

Lgr5 and stem/progenitor gene expression in gastric/gastroesophageal junction carcinoma – significance of potentially retained stemness

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Ju-Yoon Yoon, Christine Brezden-Masley, Catherine J. Streutker

MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population

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Divya Bakshi, Ashna Nagpal, Varun Sharma, Indu Sharma, Ruchi Shah, Bhanu Sharma, Amrita Bhat, Sonali Verma, Gh. Rasool Bhat, Deepak Abrol, Rahul Sharma, Samantha Vaishnavi, Rakesh Kumar

Biplane transrectal ultrasonography plus ultrasonic elastosonography and contrast-enhanced ultrasonography in T staging of rectal cancer

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Yanru Feng, Chanjuan Peng, Yuan Zhu, Luying Liu

Bioinformatic analysis reveals hub genes and pathways that promote melanoma metastasis

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Wenxing Su, Yi Guan, Biao Huang, Juanjuan Wang, Yuqian Wei, Ying Zhao, Qingqing Jiao, Jiang Ji, Daojiang Yu, Longjiang Xu

Identification of a metabolism-related gene expression prognostic model in endometrial carcinoma patients

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Pinping Jiang, Wei Sun, Ningmei Shen, Xiaohao Huang, Shilong Fu

Nomogram for individually predicting overall survival in rectal neuroendocrine tumours

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Xingyu Feng, Gengzhou Wei, Wei Wang, Yu Zhang, Yujie Zeng, Minhu Chen, Ye Chen, Jie Chen, Zhiwei Zhou, Yong Li

Homeobox proteins are potential biomarkers and therapeutic targets in gastric cancer: a systematic review and meta-analysis

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Xiao Jin, Lu Dai, Yilan Ma, Jiayan Wang, Haihao Yan, Ye Jin, Xiaojuan Zhu, Zheng Liu

Antithrombin use and mortality in patients with stage IV solid tumor-associated disseminated intravascular coagulation: a nationwide observational study in Japan

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Kohei Taniguchi, Hiroyuki Ohbe, Kazuma Yamakawa, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga

Efficacy of combination-chemotherapy with pirarubicin, ifosfamide, and etoposide for soft tissue sarcoma: a single-institution retrospective analysis

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Shiro Saito, Hisaki Aiba, Satoshi Yamada, Hideki Okamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Takanobu Otsuka, Hideki Murakami

1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression

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Luiz Henrique Gomes Matheus, Stephanie Vanin Dalmazzo, Rodrigo Barbosa Oliveira Brito, Lucas Alves Pereira, Robson José de Almeida, Cleber Pinto Camacho, Humberto Dellê

High BANCR expression is associated with worse prognosis in human malignant carcinomas: an updated systematic review and meta-analysis

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Shixu Fang, Zhou Liu, Qiang Guo, Cheng Chen, Xixian Ke, Gang Xu

Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development

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Jennifer S. Davis, Preeti Kanikarla-Marie, Mihai Gagea, Patrick L. Yu, Dexing Fang, Manu Sebastian, Peiying Yang, Ernest Hawk, Roderick Dashwood, Lenard M. Lichtenberger, David Menter, Scott Kopetz

5α-reductase inhibitors impact prognosis of urothelial carcinoma

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Chien-Sheng Wang, Ching-Chia Li, Yung-Shun Juan, Wen-Jeng Wu, Hsiang-Ying Lee

Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients

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Nerymar Ortiz-Otero, Jocelyn R. Marshall, Bradley Lash, Michael R. King

Clinical characteristics and outcome of pediatric patients diagnosed with Langerhans cell histiocytosis in pediatric hematology and oncology centers in Poland

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Anna Raciborska, Katarzyna Bilska, Jadwiga Węcławek-Tompol, Olga Gryniewicz-Kwiatkowska, Małgorzata Hnatko-Kołacz, Joanna Stefanowicz, Anna Pieczonka, Katarzyna Jankowska, Filip Pierelejewski, Tomasz Ociepa, Grażyna Sobol-Milejska, Katarzyna Muszyńska-Rosłan, Olga Michoń, Wanda Badowska, Monika Radwańska, Katarzyna Drabko

Cost-effectiveness analysis comparing companion diagnostic tests for EGFR, ALK, and ROS1 versus next-generation sequencing (NGS) in advanced adenocarcinoma lung cancer patients

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Luciene Schluckebier, Rosangela Caetano, Osvaldo Ulises Garay, Giuliana T. Montenegro, Marcelo Custodio, Veronica Aran, Carlos Gil Ferreira

Monofrequency electrical impedance mammography (EIM) diagnostic system in breast cancer screening

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Blanca Murillo-Ortiz, Abraham Hernández-Ramírez, Talia Rivera-Villanueva, David Suárez-García, Mario Murguía-Pérez, Sandra Martínez-Garza, Allyson Rodríguez-Penin, Rosario Romero-Coripuna, Xiomara Midory López-Partida

Salvage chemoradiation therapy for recurrence after radical surgery or palliative surgery in esophageal cancer patients: a prospective, multicenter clinical trial protocol

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Xiao Chang, Lei Deng, Wenjie Ni, Chen Li, Weiming Han, Lin-rui Gao, Shijia Wang, Zongmei Zhou, Dongfu Chen, Qinfu Feng, Jun Liang, Nan Bi, Jima Lv, Shugeng Gao, Yousheng Mao, Qi Xue, Zefen Xiao

ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer

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Yu-Chen Cai, Hang Yang, Ke-Feng Wang, Tan-Huan Chen, Wen-Qi Jiang, Yan-Xia Shi

Upregulated expression of LncRNA nicotinamide nucleotide transhydrogenase antisense RNA 1 is correlated with unfavorable clinical outcomes in cancers

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Chenghao Zhang, Xiaolei Ren, Zhongyue Liu, Chao Tu

From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

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Zhishan Chen, Wanqing Wen, Qiuyin Cai, Jirong Long, Ying Wang, Weiqiang Lin, Xiao-ou Shu, Wei Zheng, Xingyi Guo

Anti-proliferative activity of A. Oxyphylla and its bioactive constituent nootkatone in colorectal cancer cells

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