BMC Cancer

AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway

• Open Access
• Research

Bou-Yue Peng, Abhinay Kumar Singh, Chun-Hao Chan, Yue-Hua Deng, Pin-Ying Li, Chun-Wei Su, Chia-Yu Wu, Win-Ping Deng

Differential presence of exons (DPE): sequencing liquid biopsy by NGS. A new method for clustering colorectal Cancer patients

• Open Access
• Research

David Rubio-Mangas, Mariano García-Arranz, Yaima Torres-Rodriguez, Miguel León-Arellano, Javier Suela, Damián García-Olmo

Lymphovascular invasion represents a superior prognostic and predictive pathological factor of the duration of adjuvant chemotherapy for stage III colon cancer patients

• Open Access
• Research

Linjie Zhang, Yuxiang Deng, Songran Liu, Weili Zhang, Zhigang Hong, Zhenhai Lu, Zhizhong Pan, Xiaojun Wu, Jianhong Peng

Feasibility of three times weekly symptom screening in pediatric cancer patients

• Open Access
• Research

Maryann Calligan, Lauren Chakkalackal, Grace Dadzie, Cassandra Tardif-Theriault, Sadie Cook, Emily Vettese, Dilip Soman, Susan Kuczynski, Tal Schechter, L. Lee Dupuis, Lillian Sung

Prognostic significance of inflammatory and nutritional markers in perioperative period for patients with advanced gastric cancer

• Open Access
• Research

Ruolan Zhang, Can Hu, Jiaqing Zhang, Yanqiang Zhang, Li Yuan, Pengcheng Yu, Yi Wang, Zhehan Bao, Mengxuan Cao, Rongwei Ruan, Xiangdong Cheng, Zhiyuan Xu

Afatinib plus osimertinib in the treatment of osimertinib-resistant non-small cell lung carcinoma: a phase I clinical trial

• Open Access
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Satoru Miura, Yasuhiro Koh, Koichi Azuma, Hiroshige Yoshioka, Kenichi Koyama, Shunsuke Teraoka, Hidenobu Ishii, Kayoko Kibata, Yuichi Ozawa, Takaaki Tokito, Jun Oyanagi, Toshio Shimokawa, Takayasu Kurata, Nobuyuki Yamamoto, Hiroshi Tanaka

Clinical characteristics and prognostic factors affecting survival after radical radiotherapy for early and late post-treatment metastatic nasopharyngeal carcinoma

• Open Access
• Research

Guo-Dong Jia, Xue-Song Sun, Xiao-Yun Li, Sai-Lan Liu, Jin-Hao Yang, Qiu-Yan Chen, Li Yuan, Hai-Qiang Mai

Clinical significance of histopathological features of paired recurrent gliomas: a cohort study from a single cancer center

• Open Access
• Research

Cong Li, Shaoyan Xi, Yingshen Chen, Chengcheng Guo, Ji Zhang, Qunying Yang, Jian Wang, Ke Sai, Jing Zeng, Jing Wang, Zhiqiang Zhang, Chao Ke, Zhongping Chen

Postoperative cosmetic outcome of intraoperative radiotherapy in comparison to whole breast radiotherapy in early stage breast cancer; a retrospective cohort study

• Open Access
• Research

Nahid Nafissi, Seyed Mostafa Meshkati Yazd, Reza Shahriarirad, Saba Zangeneh, Sahar Ghorbani, Borna Farazmand, Mohammadreza Karoobi, Hamid Reza Mirzaei

Mesenchymal circulating tumor cells and Ki67: their mutual correlation and prognostic implications in hepatocellular carcinoma

• Open Access
• Research

Xihua Yang, Hanghang Ni, Zhan Lu, Jie Zhang, Qian Zhang, Shangwu Ning, Lunan Qi, Bangde Xiang

Inference of core needle biopsy whole slide images requiring definitive therapy for prostate cancer

• Open Access
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Masayuki Tsuneki, Makoto Abe, Shin Ichihara, Fahdi Kanavati

Correction: Overexpression of CENPL mRNA potentially regulated by miR-340-3p predicts the prognosis of pancreatic cancer patients

• Open Access
• Correction

Zhongyuan Cui, Ling Du, Jielong Wang, Zhongzhuan Li, Jiehong Xu, Shiyu Ou, Dongliang Li, Shasha Li, Hanfang Hu, Gang Chen, Zhixian Wu

PD-L1 is highly expressed in ovarian cancer and associated with cancer stem cells populations expressing CD44 and other stem cell markers

• Open Access
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Kholoud Alwosaibai, Salmah Aalmri, Miral Mashhour, Salim Ghandorah, Abdulraheem Alshangiti, Faisal Azam, Waleed Selwi, Lubna Gharaibeh, Yasser Alatawi, Zainab Alruwaii, Hashem O. Alsaab

The trace that is valuable: serum copper and copper to zinc ratio for survival prediction in younger patients with newly diagnosed acute myeloid leukaemia

• Open Access
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Taotao Li, Liming Shi, Wei Wei, Jiancheng Xu, Qiuju Liu

A delta-radiomic lymph node model using dynamic contrast enhanced MRI for the early prediction of axillary response after neoadjuvant chemotherapy in breast cancer patients

• Open Access
• Research

Shasha Liu, Siyao Du, Si Gao, Yuee Teng, Feng Jin, Lina Zhang

The efficacy of small molecule anti-angiogenic drugs in previously treated Thymic carcinoma

• Open Access
• Research

Yelan Guan, Xiaodong Gu, Jinfei Si, Jing Xiang, Jingwen Wei, Yue Hao, Wenxian Wang, Yan Sun

Should we screen for colorectal cancer in people aged 75 and over? A systematic review - collaborative work of the French geriatric oncology society (SOFOG) and the French federation of digestive oncology (FFCD)

• Open Access
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Lydia Guittet, Valérie Quipourt, Thomas Aparicio, Elisabeth Carola, Jean-François Seitz , Elena Paillaud, Astrid Lievre, Rabia Boulahssass, Carole Vitellius, Leila Bengrine, Florence Canoui-Poitrine, Sylvain Manfredi

Investigating the functional role of SETD6 in lung adenocarcinoma

• Open Access
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Jing Xu, Hui Zhou, Ziling Luo, Jie Chen, Man Liu

Analysis of the expression and prognostic significance of DDK complex in Hepatocarcinoma

• Open Access
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Min Wang, Zu-Hua Qiu, Yu-Zhuo Wang, Bo Lian, Jing-Kun Bai, Yong-Jie Zhou, Hong-Jie Ji

The prognostic significance of tumor-associated neutrophils and circulating neutrophils in glioblastoma (WHO CNS5 classification)

• Open Access
• Research

Xuezhen Wang, Xiaoxia Li, Yufan Wu, Jinsheng Hong, Mingwei Zhang

Patient navigation for colorectal cancer screening in deprived areas: the COLONAV cluster randomized controlled trial

• Open Access
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A. Bourmaud, Y. Benoist, F. Tinquaut, C. Allary, J. Ramone-Louis, M. Oriol, J. Kalecinski, V. Dutertre, N. Lechopier, M. Pommier, S. Rousseau, A. Dumas, P. Amiel, V. Regnier, V. Buthion, F. Chauvin

Implementation of a home-based colorectal cancer screening intervention in Malaysia (CRC-SIM)

• Open Access
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Désirée Schliemann, Kogila Ramanathan, Nor Saleha Binti Ibrahim Tamin, Ciaran O’Neill, Christopher R Cardwell, Roshidi Ismail, Zaid Kassim, Frank Kee, Tin Tin Su, Michael Donnelly

Predictors of surgery choices in women with early-stage breast cancer in China: a retrospective study

• Open Access
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Sijia Huang, Qingmo Yang, Xujuan Zheng, Ka Ming Chow, Junhua Wu, Jiemin Zhu

The anti-estrogen receptor drug, tamoxifen, is selectively Lethal to P-glycoprotein-expressing Multidrug resistant tumor cells

• Open Access
• Research

Rowa Bakadlag, Georgia Limniatis, Gabriel Georges, Elias Georges

Cuproptosis regulatory genes greatly contribute to clinical assessments of hepatocellular carcinoma

• Open Access
• Research

Changwei Ke, Shejiao Dai, Fangshi Xu, Jia Yuan, Shuting Fan, Yang Chen, Longbao Yang, Yong Li

High-dose chemotherapy with stem cell rescue to treat stage III homologous deficient breast cancer: factors influencing clinical implementation

• Open Access
• Research article

Joost G. E. Verbeek, Vincent M. T. de Jong, Hanna M. Wijnja, Agnes Jager, Sabine C. Linn, Valesca P. Retèl, Wim H. van Harten

Effects of peripheral blood leukocyte count and tumor necrosis factor-alpha on early death in acute promyelocytic leukemia

• Open Access
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Jingjing Wen, Fang Xu, Qiaolin Zhou, Lin Shi, Yiping Liu, Jing Yue, Ya Zhang, Xiaogong Liang

EOAI, a ubiquitin-specific peptidase 5 inhibitor, prevents non-small cell lung cancer progression by inducing DNA damage

• Open Access
• Research

Yuanyuan Zheng, Longhao Wang, Xiaoyu Niu, Yongjun Guo, Jiuzhou Zhao, Lifeng Li, Jie Zhao

Neoadjuvant checkpoint blockade in combination with Chemotherapy in patients with tripe-negative breast cancer: exploratory analysis of real-world, multicenter data

• Open Access
• Research

Heran Deng, Liying Wang, Na Wang, Kejin Zhang, Yanxia Zhao, Pengfei Qiu, Xiaowei Qi, Danhua Zhang, Fei Xu, Jieqiong Liu

Merkel cell carcinoma: a forty-year experience at the Peter MacCallum Cancer Centre

• Open Access
• Research

Annie J. Wang, Brendan McCann, William C. L. Soon, Paolo B. De Ieso, Mathias Bressel, Andrew Hui, Margaret Chua, David L. Kok

Recurrence and survival of patients with stage III endometrial cancer after radical surgery followed by adjuvant chemo- or chemoradiotherapy: a systematic review and meta-analysis

• Open Access
• Research

Si-yu Cao, Yu Fan, Yu-fei Zhang, Jia-ying Ruan, Yi Mu, Jin-ke Li

Validation of an anti-α-Gal IgE fluoroenzyme-immunoassay for the screening of patients at risk of severe anaphylaxis to cetuximab

• Open Access
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Julien Serrier, Jean-Baptiste Davy, Benoît Dupont, Bénédicte Clarisse, Jean-Jacques Parienti, Gautier Petit, Kathy Khoy, Yann Ollivier, Radj Gervais, Delphine Mariotte, Brigitte Le Mauff

Cancer incidence in immunocompromised patients: a single-center cohort study

• Open Access
• Research

Sabrina Ilham, Connor Willis, Kibum Kim, Karen C. Chung, Brenda M. Wood, Malinda S. Tan, Chia Jie Tan, Danielle T. Nguyen, Diana I. Brixner, David D. Stenehjem

Upregulation of the c-MYC oncogene and adjacent long noncoding RNAs PVT1 and CCAT1 in esophageal squamous cell carcinoma

• Open Access
• Research

Zahra Roohinejad, Shabbou Bahramian, Fatemeh Tash Shamsabadi, Reza Sahebi, Abolfazl Amini, Davood Sabour, Mohammad Shafiee

The Fast Cognitive Evaluation (FaCE): a screening tool to detect cognitive impairment in patients with cancer

• Open Access
• Research

Amel Baghdadli, Giovanni G. Arcuri, Clarence G. Green, Lynn R. Gauthier, Pierre Gagnon, Bruno Gagnon

Clinical features and lipid metabolism genes as potential biomarkers in advanced lung cancer

• Open Access
• Research

María Merino Salvador, Lara Paula Fernández, Juan Moreno-Rubio, Gonzalo Colmenarejo, Enrique Casado, Ana Ramírez de Molina, María Sereno

Comparison of whole-body 18F-FDG PET/CT and PET/MRI for distant metastases in patients with malignant tumors: a meta-analysis

• Open Access
• Research

Cici Zhang, Zhishan Liang, Wei Liu, Xuwen Zeng, Yuzhen Mo

Rapid and label-free detection of gastrointestinal stromal tumor via a combination of two-photon microscopy and imaging analysis

• Open Access
• Research

Lianhuang Li, Xingxin Huang, Shichao Zhang, Zhenlin Zhan, Deyong Kang, Guoxian Guan, Shuoyu Xu, Yongjian Zhou, Jianxin Chen

Identification and clinical validation of key genes as the potential biomarkers in colorectal adenoma

• Open Access
• Research

Bangting Wang, Jiting Zhang, Xin Wang, Lili Zhao, Yan Wang, Zhining Fan, Li Liu, Wenqing Gao

Correction: Carnitine palmitoyl transferase 1 A is a novel diagnostic and predictive biomarker for breast cancer

• Open Access
• Correction

Zheqiong Tan, Yaru Zou, Man Zhu, Zhenzhao Luo, Tangwei Wu, Chao Zheng, Aqing Xie, Hui Wang, Shiqiang Fang, Shuiyi Liu, Yong Li, Zhongxin Lu

Risk model and factors for prediction of response to neoadjuvant chemotherapy in patients with advanced gastric cancer-a two-center cohort study

• Open Access
• Research

Xian-Wen Liang, Wei-Sheng Xiao, Hao Lei, Qian-Cheng Huag, Yu-Lan Dong, Fang Wang, Wei-Peng Qing

Development of an integrated predictive model for postoperative glioma-related epilepsy using gene-signature and clinical data

• Open Access
• Research

Lianwang Li, Chuanbao Zhang, Zheng Wang, Yinyan Wang, Yuhao Guo, Chong Qi, Gan You, Zhong Zhang, Xing Fan, Tao Jiang

Porphyromonas gingivalis predicts local recurrence after endoscopic submucosal dissection of early esophageal squamous cell carcinoma or precancerous lesion

• Open Access
• Research

She-Gan Gao, Zhi-Peng Qi, Yi-Jun Qi, Ying-Yong Hou, Yi-Wen Liu, Meng-Xiang Li, Bing Li, Di Sun, Qiang Shi, Shi-Lun Cai, Ping-Hong Zhou, Yun-Shi Zhong

Claudin18.2 as a potential therapeutic target for primary ovarian mucinous carcinomas and metastatic ovarian mucinous carcinomas from upper gastrointestinal primary tumours

• Open Access
• Research

Fujun Wang, Yao Yang, Xiuzhen Du, Xiaoying Zhu, Yanjiao Hu, Changyu Lu, Lei Sui, Han Zhao, Kejuan Song, Qin Yao

A meta-validated immune infiltration-related gene model predicts prognosis and immunotherapy sensitivity in HNSCC

• Open Access
• Research

Yinghe Ding, Ling Chu, Qingtai Cao, Hanyu Lei, Xinyu Li, Quan Zhuang

Umbrella review of basket trials testing a drug in tumors with actionable genetic biomarkers

• Open Access
• Research

Alyson Haslam, Timothée Olivier, Jordan Tuia, Vinay Prasad

Primary head and neck cancer cell cultures are susceptible to proliferation of Epstein-Barr virus infected lymphocytes

• Open Access
• Research

Senyao Shao, Lars Uwe Scholtz, Sarah Gendreizig, Laura Martínez-Ruiz, Javier Florido, Germaine Escames, Matthias Schürmann, Carsten Hain, Leonie Hose, Almut Mentz, Pascal Schmidt, Menghang Wang, Peter Goon, Michael Wehmeier, Frank Brasch, Jörn Kalinowski, Felix Oppel, Holger Sudhoff

Trends in overall mortality among US veterans with primary myelofibrosis

• Open Access
• Research

Tsewang Tashi, Jingbo Yu, Shivani Pandya, Christopher Dieyi, Robyn Scherber, Shreekant Parasuraman

Normalization of tumor markers and a clear resection margin affect progression-free survival of patients with unresectable pancreatic cancer who have undergone conversion surgery

• Open Access
• Research

Xiang Li, Xinyuan Liu, Na Lu, Yiwen Chen, Xiaochen Zhang, Chengxiang Guo, Wenbo Xiao, Xing Xue, Ke Sun, Meng Wang, Shunliang Gao, Yan Shen, Min Zhang, Jian Wu, Risheng Que, Jun Yu, Xueli Bai, Tingbo Liang

Metabolic syndrome and its components predict the biochemical recurrence and adverse pathological features of patients following radical prostatectomy: a propensity score matching study

• Open Access
• Research

Zenan Liu, Xuehua Zhu, Jide He, Jian Lu

Neoadjuvant chemotherapy with weekly cisplatin and paclitaxel followed by chemoradiation for locally advanced cervical cancer

• Open Access
• Research

Jing Li, Ya Li, Huafeng Wang, Lifei Shen, Qun Wang, Siqi Shao, Yuhong Shen, Haoping Xu, Hua Liu, Rong Cai, Weiwei Feng

Phosphorylation of TGIF2 represents a therapeutic target that drives EMT and metastasis of lung adenocarcinoma

• Open Access
• Research

Renle Du, Chen Wang, Jingjing Liu, Keyan Wang, Liping Dai, Wenzhi Shen

Prognostic significance of preoperative serum tumor markers in hepatoid adenocarcinoma of stomach (HAS)

• Open Access
• Research

Xuesong Yang, Anqiang Wang, Jialin Li, Kai Zhou, Ke Ji, Xin Ji, Ji Zhang, Xiaojiang Wu, Zhaode Bu

Carboxylated superparamagnetic Fe3O4 nanoparticles modified with 3-amino propanol and their application in magnetic resonance tumor imaging

• Open Access
• Research

Changyuan Wang, Yang Wang, Wangchuan Xiao, Xiaohua Chen, Renfu Li, Zhiyong Shen, Fengchun Lu

Notch3 signaling promotes colorectal tumor growth by enhancing immunosuppressive cells infiltration in the microenvironment

• Open Access
• Research

Kai Huang, Wenwu Luo, Jinmei Fang, Changjun Yu, Guangjie Liu, Xiaodong Yuan, Yun Liu, Wenyong Wu

Comparison of CT derived body composition at the thoracic T4 and T12 with lumbar L3 vertebral levels and their utility in patients with rectal cancer

• Open Access
• Research

Aisha A Arayne, Richard Gartrell, Jing Qiao, Paul N Baird, Justin MC Yeung

Construction and verification of a novel circadian clock related long non-coding RNA model and prediction of treatment for survival prognosis in patients with hepatocellular carcinoma

• Open Access
• Research

Zhen Zhang, Wenhui Gao, Xiaoning Tan, Tianhao Deng, Wanshuang Zhou, Huiying Jian, Puhua Zeng

Detection of pancreatic cancer with two- and three-dimensional radiomic analysis in a nationwide population-based real-world dataset

• Open Access
• Research

Dawei Chang, Po-Ting Chen, Pochuan Wang, Tinghui Wu, Andre Yanchen Yeh, Po-Chang Lee, Yi-Hui Sung, Kao-Lang Liu, Ming-Shiang Wu, Dong Yang, Holger Roth, Wei-Chih Liao, Weichung Wang

Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet

• Open Access
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Suresh R. Giri, Bibhuti Bhoi, Chitrang Trivedi, Akshyaya Rath, Rohan Rathod, Anish Sharma, Ramchandra Ranvir, Shekhar Kadam, Kailash Ingale, Hiren Patel, Abraham Nyska, Mukul R. Jain

Colon and rectal cancer treatment patterns and their associations with clinical, sociodemographic and lifestyle characteristics: analysis of the Australian 45 and Up Study cohort

• Open Access
• Research

Sarsha Yap, Emily He, Sam Egger, David E Goldsbury, Jie-Bin Lew, Preston J Ngo, Joachim Worthington, Hannah Rillstone, John R Zalcberg, Jeff Cuff, Robyn L Ward, Karen Canfell, Eleonora Feletto, Julia Steinberg

Biparametric magnetic resonance imaging-based radiomics features for prediction of lymphovascular invasion in rectal cancer

• Open Access
• Research

Pengfei Tong, Danqi Sun, Guangqiang Chen, Jianming Ni, Yonggang Li

Enhancement of radiation therapy by indoleamine 2,3 dioxygenase 1 inhibition through multimodal mechanisms

• Open Access
• Research

Hiroaki Nozawa, Tetsuro Taira, Hirofumi Sonoda, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Shinya Abe, Soichiro Ishihara

DUPAN-II normalisation as a biological indicator during preoperative chemoradiation therapy for resectable and borderline resectable pancreatic cancer

• Open Access
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Shinichiro Hasegawa, Hidenori Takahashi, Hirofumi Akita, Yosuke Mukai, Manabu Mikamori, Kei Asukai, Daisaku Yamada, Hiroshi Wada, Yoshiaki Fujii, Takahito Sugase, Masaaki Yamamoto, Tomohira Takeoka, Naoki Shinno, Hisashi Hara, Takashi Kanemura, Naotsugu Haraguchi, Junichi Nishimura, Chu Matsuda, Masayoshi Yasui, Takeshi Omori, Hiroshi Miyata, Masayuki Ohue, Osamu Ishikawa, Masato Sakon

Development and validation of nomogram of peritoneal metastasis in gastric cancer based on simplified clinicopathological features and serum tumor markers

• Open Access
• Research

Jia Yang, Hongtao Su, Tao Chen, Xinhua Chen, Hao Chen, Guoxin Li, Jiang Yu

Patient perspectives on considerations, tradeoffs, and experiences with multiple myeloma treatment selection: a qualitative descriptive study

• Open Access
• Research

Carrie Dombeck, Teresa Swezey, Juan Marcos Gonzalez Sepulveda, Bryce B. Reeve, Thomas W. LeBlanc, David Chandler, Amy Corneli

Risk thresholds for patients to switch between daily tablets and biweekly infusions in second-line treatment for advanced hepatocellular carcinoma: a patient preference study

• Open Access
• Research

Neehar D. Parikh, Allicia Girvan, Joshua Coulter, Jonathon Gable, Jiat Ling Poon, Sangmi Kim, Anindya Chatterjee, Marco Boeri

Patterns of staging, treatment, and mortality in gastric, colorectal, and lung cancer among older adults with and without preexisting dementia: a Japanese multicentre cohort study

• Open Access
• Research article

Toshitaka Morishima, Yoshihiro Kuwabara, Mari Kajiwara Saito, Satomi Odani, Haruka Kudo, Mizuki Kato, Kayo Nakata, Isao Miyashiro

Biomarker analysis for patients with pancreatic cancer treated with nanoliposomal irinotecan plus 5-fluorouracil/leucovorin

• Open Access
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Takeshi Kawakami, Akiko Todaka, Kotoe Oshima, Kunihiro Fushiki, Satoshi Hamauchi, Takahiro Tsushima, Tomoya Yokota, Yusuke Onozawa, Hirofumi Yasui, Kentaro Yamazaki

Management and outcomes of adolescent and young adult sarcoma patients: results from the French nationwide database NETSARC

• Open Access
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Pierre Kubicek, Axel Le Cesne, Cyril Lervat, Maud Toulmonde, Christine Chevreau, Florence Duffaud, Louis-Romée Le Nail, Magali Morelle, Nathalie Gaspar, Cécile Vérité, Marie-Pierre Castex, Nicolas Penel, Esma Saada, Sylvain Causeret, François Bertucci, Christophe Perrin, Emmanuelle Bompas, Daniel Orbach, Valérie Laurence, Sophie Piperno-Neumann, Philippe Anract, Maria Rios, Jean-Claude Gentet, Éric Mascard, Stéphanie Pannier, Pascale Blouin, Sébastien Carrère, Loïc Chaigneau, Pauline Soibinet-Oudot, Nadège Corradini, Pascaline Boudou-Rouquette, Jean-Christophe Ruzic, Valérie Lebrun-Ly, Pascale Dubray-Longeras, Sharmini Varatharajah, Céleste Lebbe, Mickaël Ropars, Jean-Emmanuel Kurtz, Cécile Guillemet, Jean-Pierre Lotz, Juliane Berchoud, Grégory Cherrier, Françoise Ducimetière, Claire Chemin, Antoine Italiano, Charles Honoré, Emmanuel Desandes, Jean-Yves Blay, François Gouin, Perrine Marec-Bérard

Correction: Stereotactic ablative radiotherapy or best supportive care in patients with localized pancreatic cancer not receiving chemotherapy and surgery (PANCOSAR): a nationwide multicenter randomized controlled trial according to a TwiCs design

• Open Access
• Correction

D. Doppenberg, M. G. Besselink, C. H. J. van Eijck, M. P. W. Intven, B. Groot Koerkamp, G. Kazemier, H. W. M. van Laarhoven, M. Meijerink, I. Q. Molenaar, J. J. M. E. Nuyttens, R. van Os, H. C. van Santvoort, G. van Tienhoven, H. M. Verkooijen, E. Versteijne, J. W. Wilmink, F. J. Lagerwaard, A. M. E. Bruynzeel

Application of the CDK9 inhibitor FIT-039 for the treatment of KSHV-associated malignancy

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Tetsunori Sakamoto, Masahiko Ajiro, Akira Watanabe, Shingo Matsushima, Keiji Ueda, Masatoshi Hagiwara

Role of antiangiogenic agents in first-line treatment for advanced NSCLC in the era of immunotherapy

• Open Access
• Research article

Lan-Lan Pang, Jia-Di Gan, Yi-Hua Huang, Jun Liao, Wei-Tao Zhuang, Wael-Abdullah-Sultan Ali, Shao-Dong Hong, Li Zhang, Wen-Feng Fang

Two-institution results of Stereotactic Body Radiation Therapy (SBRT) for treating adrenal gland metastases from liver cancer

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Bichun Xu, Xianzhi Zhao, Di Chen, Wenjuan Zhao, Xiaoyan Wang, Changhua Ding, Zhiyong Yuan, Huojun Zhang

Clinical outcomes in patients relapsed/refractory after ≥2 prior lines of therapy for follicular lymphoma: a systematic literature review and meta-analysis

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Steve Kanters, Graeme Ball, Brad Kahl, Adriana Wiesinger, Eve H. Limbrick-Oldfield, Akshay Sudhindra, Julia Thornton Snider, Anik R. Patel

Correction: Effect of chlorhexidine Mouthrinse on prevention of microbial contamination during EBUS-TBNA: a randomized controlled trial

• Open Access
• Correction

Na Young Kim, Jae Hyeon Park, Jimyung Park, Nakwon Kwak, Sun Mi Choi, Young Sik Park, Chang-Hoon Lee, Jaeyoung Cho

Identification and validation of crucial lnc-TRIM28-14 and hub genes promoting gastric cancer peritoneal metastasis

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• Research

Chao Dong, Fujuan Luan, Wenyan Tian, Kaipeng Duan, Tao Chen, Jiayu Ren, Weikang Li, Dongbao Li, Qiaoming Zhi, Jin Zhou

Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer

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Yohei Harada, Akemi Sato, Hideaki Nakamura, Keita Kai, Sho Kitamura, Tomomi Nakamura, Yuki Kurihara, Sadakatsu Ikeda, Eisaburo Sueoka, Shinya Kimura, Naoko Sueoka-Aragane

Risk of seizures in a population of women with BRCA-positive metastatic breast cancer from an electronic health record database in the United States

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Alexander Liede, Wendy Sebby, Ashok Kumar Reddy Miriyala, Ravi Potluri, Debasish Mazumder, Anirban Ghosh, Eros Papademetriou, Ryan Kilpatrick, Jerzy E. Tyczynski

C/EBPβ expression decreases in cervical cancer and leads to tumorigenesis

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Haichen Long, Yangyang Li, Huijuan Wang, Bingxuan Guo, Shuyan Song, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao, Zemin Pan

Mortality and disability-adjusted life years for smoking-attributed cancers from 1990 to 2019 in the north Africa and middle east countries: a systematic analysis for the global burden of disease study 2019

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Leila Rezakhani, Mitra Darbandi, Zahra Khorrami, Shima Rahmati, Fatemeh Khosravi Shadmani

Risk factors of childhood cancer in Armenia: a case-control study

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Manushak Avagyan, Anahit Demirchyan, Lusine Abrahamyan

Comprehensive mastocytosis data analysis from a single center

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Tarık Onur Tiryaki, Sıdıka Gülkan Özkan, Simge Erdem, Aynur Dağlar Aday, İpek Yönal Hindilerden, Aslı Gelincik, Can Baykal, Gülçin Yegen, İbrahim Öner Doğan, Nesimi Büyükbabani, Meliha Nalçacı, Akif Selim Yavuz

Peripheral blood lymphocytes differentiation patterns in responses / outcomes to immune checkpoint blockade therapies in non-small cell lung cancer: a retrospective study

• Open Access
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Xiaoyue Du, Shaodi Wen, Run Shi, Jingwei Xia, Ruotong Wang, Yihan Zhang, Banzhou Pan, Xiaoliu Wu, Wei Zhu, Jifeng Feng, Xin Wang, Bo Shen

A clinicopathological study and survival analysis of 99 breast cancers with HER2/CEP17 ratio ≥ 2.0 and an average HER2 copy number < 4.0 per cell in China

• Open Access
• Research

Shuling Zhou, Hong Lv, Anqi Li, Ming Li, Siyuan Zhong, Hongfen Lu, Xiaoyan Zhou, Qianming Bai, Wentao Yang

MYEOV overexpression induced by demethylation of its promoter contributes to pancreatic cancer progression via activation of the folate cycle/c-Myc/mTORC1 pathway

• Open Access
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Shoichiro Tange, Tomomi Hirano, Masashi Idogawa, Eishu Hirata, Issei Imoto, Takashi Tokino

Tumor micronecrosis predicts poor prognosis of patients with hepatocellular carcinoma after liver transplantation

• Open Access
• Research

Yangyang Wang, Wei Zhang, Hongbin Ge, Xu Han, Jiangchao Wu, Xuqi Sun, Ke Sun, Wanyue Cao, Chao Huang, Jingsong Li, Qi Zhang, Tingbo Liang

IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways

• Open Access
• Research

Wenpeng Cai, Yongfang Ma, Li Song, Niandie Cao, Jiafeng Gao, Shuping Zhou, Xiaolong Tang

Risk stratification and prognostic value of multi-modal MRI-based radiomics for extranodal nasal-type NK/T-cell lymphoma

• Open Access
• Research

Yu-Ting Zhao, Si-Ye Chen, Xin Liu, Yong Yang, Bo Chen, Yong-Wen Song, Hui Fang, Jing Jin, Yue-Ping Liu, Hao Jing, Yuan Tang, Ning Li, Ning-Ning Lu, Shu-Lian Wang, Han Ouyang, Chen Hu, Jin Liu, Zhi Wang, Fan Chen, Lin Yin, Qiu-Zi Zhong, Kuo Men, Jian-Rong Dai, Shu-Nan Qi, Ye-Xiong Li

PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer

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Sherif Mohamed Elsharkawi, Dalal Elkaffash, Pacint Moez, Nour El-Etreby, Eman Sheta, Raghda Saad Zaghloul Taleb

Serum and ascites tumor markers in the diagnostic and prognostic prediction for appendiceal pseudomyxoma peritonei

• Open Access
• Research

Bing Wang, Ruiqing Ma, Benqiang Rao, Hongbin Xu

Spectral CT-based radiomics signature for distinguishing malignant pulmonary nodules from benign

• Open Access
• Research

Hang Xu, Na Zhu, Yong Yue, Yan Guo, Qingyun Wen, Lu Gao, Yang Hou, Jin Shang

Global burden of prostate cancer attributable to smoking among males in 204 countries and territories, 1990–2019

• Open Access
• Research

Hanfei Zhang, Dingping Huang, Yingfeng Zhang, Xia Wang, Jiangtao Wu, Daqing Hong

Exploring the relationships between hormone receptor, HER2 status, and bone involvement in the first distant metastases of in Chinese breast cancer patients who lacked HER2 targeted therapy

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Zhifeng Jia, Muwei Dai, Yuguang Shang, Yue Li, Zhensheng Li

Safety and efficacy of trifluridine/tipiracil in previously treated metastatic colorectal cancer: final results from the phase IIIb single-arm PRECONNECT study by duration of therapy

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Julien Taieb, Timothy Price, Loïck Vidot, Bénédicte Chevallier, Lucjan Wyrwicz, Jean-Baptiste Bachet

Advanced Ann Arbor stage and age over 60 years as prognostic predictors in patients with primary cervical lymphoma: a retrospective cohort study and systematic review

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Lingyun Gao, Xiaoran Chen, Jing Zhao, Anli Xu, Meijuan Liu, Hongna Yu, Shujun Kong, Sijian Li

Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development

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Hongjuan Chai, Chunpeng Pan, Mingyang Zhang, Haizhong Huo, Haiyan Shan, Jugang Wu

MR imaging phenotypes and features associated with pathogenic mutation to predict recurrence or metastasis in breast cancer

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Zhenzhen Shao, Jinpu Yu, Yanan Cheng, Wenjuan Ma, Peifang Liu, Hong Lu

High resolution dermal ultrasound (US) combined with superficial radiation therapy (SRT) versus non-image guided SRT or external beam radiotherapy (XRT) in early-stage epithelial cancer: a comparison of studies

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Lio Yu, Mairead Moloney, Songzhu Zheng, James Rogers

Pre-operative anemia and peri-operative transfusion are associated with poor oncologic outcomes in cancers of the esophagus: potential impact of patient blood management on cancer outcomes

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Joseph P. Connor, Eric Destrampe, Daniel Robbins, Aaron S. Hess, Daniel McCarthy, James Maloney

The optimal minimum lymph node count for carcinoembryonic antigen elevated colon cancer: a population-based study in the SEER set and External set

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Hao Zhang, Chunlin Wang, Yunxiao Liu, Hanqing Hu, Qingchao Tang, Rui Huang, Meng Wang, Guiyu Wang

The prognostic value of the advanced lung cancer inflammation index in patients with gastrointestinal malignancy

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Lilong Zhang, Kailiang Zhao, Tianrui kuang, Kunpeng Wang, Dongqi Chai, Zhendong Qiu, Rongqiang Liu, Wenhong Deng, Weixing Wang

Multi-omics analyses of CD276 in pan-cancer reveals its clinical prognostic value in glioblastoma and other major cancer types

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Lirui Dai, Xuyang Guo, Zhe Xing, Yiran Tao, Wulong Liang, Zimin Shi, Weihua Hu, Shaolong Zhou, Xinjun Wang

Palbociclib plus endocrine therapy in hormone receptor-positive and HER2 negative metastatic breast cancer: a multicenter real-world study in the northwest of China

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Jiao Yang, Bing Zhao, Xiaoling Ling, Donghui Li, Jiuda Zhao, Yonggang Lv, Guangxi Wang, Xinlan Liu, Nanlin Li, Jin Yang

Clinical and genomic features in patients with second primary glioblastoma following first primary renal cell carcinoma

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Guang-Tao Zhang, Qi Liu, Fu-Xing Zuo, Hou-Jie Liu, Song-Quan Wang, Qing Yuan, Ang-Si Liu, Ke Hu, Xiao-Li Meng, Wei-Jia Wang, Hai-Peng Qian, Jing-Hai Wan, Hong-Qing Cai

Novel cuproptosis-related long non-coding RNA signature to predict prognosis in prostate carcinoma

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Xiaofeng Cheng, Zhenhao Zeng, Heng Yang, Yujun Chen, Yifu Liu, Xiaochen Zhou, Cheng Zhang, Gongxian Wang

Combined anti-C1-INH and radiotherapy against glioblastoma

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Emma Liljedahl, Elise Konradsson, Emma Gustafsson, Karolina Förnvik Jonsson, Jill K. Olofsson, Kurt Osther, Crister Ceberg, Henrietta Nittby Redebrandt

Incidence and risk of hypertension associated with PARP inhibitors in cancer patients: a systematic review and meta-analysis

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Xiu Chen, Qinglian Wen, Liqiu Kou, Xiaolu Xie, Jun Li, Yaling Li

Integrated single-cell and bulk RNA sequencing analysis identifies a cancer-associated fibroblast-related gene signature for predicting survival and therapy in gastric cancer

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Zhiyang Zhou, Sixuan Guo, Shuhui Lai, Tao Wang, Yao Du, Junping Deng, Shun Zhang, Ge Gao, Jiangnan Zhang

Protocol for a confirmatory trial of the effectiveness and safety of palliative arterial embolization for painful bone metastases

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Sadamoto Zenda, Yasunori Arai, Shunsuke Sugawara, Yoshitaka Inaba, Kazuki Hashimoto, Kouji Yamamoto, Yusuke Saigusa, Takashi Kawaguchi, Sanae Shimada, Marie Yokoyama, Tempei Miyaji, Tomoka Okano, Naoki Nakamura, Eisuke Kobayashi, Tatsuya Takagi, Yoshihisa Matsumoto, Yosuke Uchitomi, Miyuki Sone

Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma

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Junfeng Li, Jianjie Li, Huifeng Hao, Fangliang Lu, Jia Wang, Menglei Ma, Bo Jia, Minglei Zhuo, Jingjing Wang, Yujia Chi, Xiaoyu Zhai, Yuyan Wang, Meina Wu, Tongtong An, Jun Zhao, Fan Yang, Ziping Wang

Using CT radiomic features based on machine learning models to subtype adrenal adenoma

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Shouliang Qi, Yifan Zuo, Runsheng Chang, Kun Huang, Jing Liu, Zhe Zhang

Final analysis of the phase 3 randomized clinical trial comparing HD201 vs. referent trastuzumab in patients with ERBB2-positive breast cancer treated in the neoadjuvant setting

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Xavier Pivot, Alexey Georgievitch Manikhas, Volodymyr Shamrai, Giorgi Dzagnidze, Hwoei Fen Soo Hoo, Viriya Kaewkangsadan, Fausto Petrelli, Cristian Villanueva, Jamie Kim, Sumita Pradhan, Litha Jaison, Peggy Feyaerts, Leonard Kaufman, Marie-Paule Derde, Filip Deforce, David G. Cox

Characterisation of tumour-immune phenotypes and PD-L1 positivity in squamous bladder cancer

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Max Jung, Michael Rose, Ruth Knuechel, Chiara Loeffler, Hannah Muti, Jakob Nikolas Kather, Nadine T. Gaisa

Factors associated with the uptake of clinical breast examination among women of reproductive age in Lesotho: analysis of a national survey

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Agani Afaya, Timothy Tienbia Laari, Abdul Aziz Seidu, Richard Adongo Afaya, Silas Selorm Daniels-Donkor, Vida Nyagre Yakong, Bright Opoku Ahinkorah

Cardiac and obstetric outcomes of pregnancies for women after cardiotoxic therapy in childhood: a single center observational study

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Julius C. Heemelaar, Steffie Heemelaar, Svenja N. Hertel, J. Wouter Jukema, Marieke Sueters, Marloes Louwerens, M. Louisa Antoni

IGF2BP3 overexpression predicts poor prognosis and correlates with immune infiltration in bladder cancer

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Wei Huang, Lizhen Zhu, Haoxuan Huang, Yuanyuan Li, Gongxian Wang, Cheng Zhang

Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

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Alvan Amos, Ning Jiang, Dan Zong, Jiajia Gu, Jiawei Zhou, Li Yin, Xia He, Yong Xu, Lirong Wu

Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma

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Ah-Jung Jeon, Yue-Yang Teo, Karthik Sekar, Shay Lee Chong, Lingyan Wu, Sin-Chi Chew, Jianbin Chen, Raden Indah Kendarsari, Hannah Lai, Wen Huan Ling, Neslihan Arife Kaya, Jia Qi Lim, Adaikalavan Ramasamy, Gokce Oguz, Alexander Yaw-Fui Chung, Chung Yip Chan, Peng-Chung Cheow, Juinn Huar Kam, Krishnakumar Madhavan, Alfred Kow, Iyer Shridhar Ganpathi, Tony Kiat Hon Lim, Wei-Qiang Leow, Shihleone Loong, Tracy Jiezhen Loh, Wei Keat Wan, Gwyneth Shook Ting Soon, Yin Huei Pang, Boon Koon Yoong, Diana Bee-Lan Ong, Jasmine Lim, Vanessa H. de Villa, Rouchelle D.dela Cruz, Rawisak Chanwat, Jidapa Thammasiri, Glenn K. Bonney, Brian K. P. Goh, Greg Tucker-Kellogg, Roger Sik Yin Foo, Pierce K. H. Chow

Multiparameter diagnostic model based on 18F-FDG PET metabolic parameters and clinical variables can differentiate nonmetastatic gallbladder cancer and cholecystitis

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Can Li, Xiaohui Luan, Xiao Bi, Shengxin Chen, Yue Pan, Jingfeng Zhang, Yun Han, Xiaodan Xu, Guanyun Wang, Baixuan Xu

LncRNA WEE2-AS1 is a diagnostic biomarker that predicts poor prognoses in patients with glioma

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Xuqiang Zhu, Di Chen, Yiyu Sun, Shuo Yang, Weiguang Wang, Bing Liu, Peng Gao, Xueyuan Li, Lixin Wu, Siqi Ma, Wenyang Lin, Jiwei Ma, Dongming Yan

Safety and efficacy of Pucotenlimab (HX008) - a humanized immunoglobulin G4 monoclonal antibody in patients with locally advanced or metastatic melanoma: a single-arm, multicenter, phase II study

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Chuanliang Cui, Yu Chen, Zhiguo Luo, Zhengyun Zou, Yu Jiang, Hongming Pan, Qingxia Fan, Jianfu Zhao, Qing Xu, Renbing Jiang, Xuan Wang, Taiyang Ma, Zhen Guo, Lu Si, Zhihong Chi, Xinan Sheng, Yiwei Dou, Qian Tan, Di Wu, Jun Guo

1,5-Anhydroglucitol promotes pre-B acute lymphocytic leukemia progression by driving glycolysis and reactive oxygen species formation

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Huasu Zhu, Huixian Ma, Na Dong, Min Wu, Dong Li, Linghong Liu, Qing Shi, Xiuli Ju

The exploration of B cell maturation antigen expression in plasma cell dyscrasias beyond multiple myeloma

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Yanjie Xu, Xia Mao, Yimei Que, Menglei Xu, Chunhui Li, Varlene Daniela Fernandes Almeida, Di Wang, Chunrui Li

Mean platelet volume/platelet count ratio in combination with tumor markers in colorectal cancer: a retrospective clinical study

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Huan Zhang, Fan Lin, Zhuocai Wang

HELLPAR/RRM2 axis related to HMMR as novel prognostic biomarker in gliomas

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Huaxin Zhu, Jiacong Tan, Xinyi Pan, Hengyang Ouyang, Zhixiong Zhang, Meihua Li, Yeyu Zhao

Early relapse is an adverse prognostic factor for survival outcomes in patients with oral cavity squamous cell carcinoma: results from a nationwide registry study

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Chi-Ying Tsai, Yu-Wen Wen, Shu-Ru Lee, Shu-Hang Ng, Chung-Jan Kang, Li-Yu Lee, Chuen Hsueh, Chien-Yu Lin, Kang-Hsing Fan, Hung-Ming Wang, Chia-Hsun Hsieh, Chih-Hua Yeh, Chih-Hung Lin, Chung-Kan Tsao, Tuan-Jen Fang, Shiang-Fu Huang, Li-Ang Lee, Ku-Hao Fang, Yu-Chien Wang, Wan-Ni Lin, Li-Jen Hsin, Tzu-Chen Yen, Nai-Ming Cheng, Chun-Ta Liao

Sarcopenia as a risk factor of progression-free survival in patients with metastases: a systematic review and meta-analysis

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Lingli Luo, Xiangru Shen, Shuai Fang, Teng Wan, Pan Liu, Peiling Li, Haifeng Tan, Yong Fu, Weiming Guo, Xiaojun Tang

Deep learning-based multifeature integration robustly predicts central lymph node metastasis in papillary thyroid cancer

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Zhongzhi Wang, Limeng Qu, Qitong Chen, Yong Zhou, Hongtao Duan, Baifeng Li, Yao Weng, Juan Su, Wenjun Yi

CD1C is associated with breast cancer prognosis and immune infiltrates

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Xiao Chen, Jianzhong Zhang, Xinhan Lei, Lei Yang, Wanwan Li, Lu Zheng, Shuai Zhang, Yihan Ding, Jianing Shi, Lei Zhang, Jia Li, Tong Tang, WenJun Jia

LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer

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Zhipeng Du, Fangxiao Zhang, Lei Liu, Hui Shen, Tingting Liu, Jing Jin, Nanxi Yu, Zhijie Wan, Hang Wang, Xuguang Hu, Yuanyuan Chen, Jianming Cai

Tumor necrosis factor-α-inducible protein 8-like protein 3 (TIPE3): a novel prognostic factor in colorectal cancer

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Yue Xu, Yong Zhu, Hengbo Xia, Yanan Wang, Lin Li, Hong Wan, Shuping Zhang, Aman Xu, Liecheng Wang, Jiao Gong, Pingping Zhang

Evaluating patient reported outcomes and experiences in a novel proton beam clinic – challenges, activities, and outcomes of the ProtonCare project

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K Sjövall, U Langegård, P Fransson, E Nevo-Ohlsson, I Kristensen, K Ahlberg, B Johansson

Pan-cancer analysis: predictive role of TAP1 in cancer prognosis and response to immunotherapy

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Zewei Tu, Kuangxun Li, Qiankun Ji, Yuyang Huang, Shigang Lv, Jingying Li, Lei Wu, Kai Huang, Xingen Zhu

Preparation of chitosan nanoparticle containing recombinant CD44v antigen and evaluation of its immunization capacity against breast cancer in BALB/c mice

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Elaheh Gheybi, Ahmad Asoodeh, Jafar Amani

Integrated analysis of the relation to tumor immune microenvironment and predicted value of Stonin1 gene for immune checkpoint blockage and targeted treatment in kidney renal clear cell carcinoma

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Axiu Zheng, Jianrong Bai, Yanping Ha, Yaping Yu, Yonghao Fan, Meihua Liang, Yanda Lu, Zhihua Shen, Botao Luo, Wei Jie

Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy

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Cengiz Karacin, Berna Oksuzoglu, Ayşe Demirci, Merve Keskinkılıç, Naziyet Köse Baytemür, Funda Yılmaz, Oğuzhan Selvi, Dilek Erdem, Esin Avşar, Nail Paksoy, Necla Demir, Sema Sezgin Göksu, Sema Türker, Ertuğrul Bayram, Abdüssamet Çelebi, Hatice Yılmaz, Ömer Faruk Kuzu, Seda Kahraman, İvo Gökmen, Abdullah Sakin, Ali Alkan, Erdinç Nayır, Muzaffer Uğraklı, Ömer Acar, İsmail Ertürk, Hacer Demir, Ferit Aslan, Özlem Sönmez, Taner Korkmaz, Özde Melisa Celayir, İbrahim Karadağ, Erkan Kayıkçıoğlu, Teoman Şakalar, İlker Nihat Öktem, Tülay Eren, Enes Erul, Eda Eylemer Mocan, Ziya Kalkan, Nilgün Yıldırım, Yakup Ergün, Baran Akagündüz, Serdar Karakaya, Engin Kut, Fatih Teker, Burçin Çakan Demirel, Kubilay Karaboyun, Elvina Almuradova, Olçun Ümit Ünal, Abdilkerim Oyman, Deniz Işık, Kerem Okutur, Buğra Öztosun, Burcu Belen Gülbağcı, Mehmet Emin Kalender, Elif Şahin, Mustafa Seyyar, Özlem Özdemir, Fatih Selçukbiricik, Metin Kanıtez, İsa Dede, Mahmut Gümüş, Erhan Gökmen, Arzu Yaren, Serkan Menekşe, Senar Ebinç, Sercan Aksoy, Gökşen İnanç İmamoğlu, Mustafa Altınbaş, Bülent Çetin, Başak Oyan Uluç, Özlem Er, Nuri Karadurmuş, Atike Pınar Erdoğan, Mehmet Artaç, Özgür Tanrıverdi, İrfan Çiçin, Mehmet Ali Nahit Şendur, Esin Oktay, İbrahim Vedat Bayoğlu, Semra Paydaş, Adnan Aydıner, Derya Kıvrak Salim, Çağlayan Geredeli, Tuğba Yavuzşen, Mutlu Doğan, İlhan Hacıbekiroğlu

Association between diverticular disease and colorectal cancer: a bidirectional mendelian randomization study

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Yanxi Zhang, Han Zhang, Jinghan Zhu, Yazhou He, Peng Wang, Doudou Li, Xiaozhuan Liu, Wen Jin, Junxi Zhang, Chuan Xu, Zengli Yu, Xin Zhao, Lingling Cui

GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

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Brooke A. Marks, Ilissa M. Pipia, Chinatsu Mukai, Sachi Horibata, Edward J. Rice, Charles G. Danko, Scott A. Coonrod

Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation

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Pan-ling Xu, Chien-shan Cheng, Ting Wang, Shu Dong, Ping Li

Associations of financial toxicity with symptoms and unplanned healthcare utilization among cancer patients taking oral chemotherapy at home: a prospective observational study

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Yongfeng Chen, Zhenxiang Chen, Haiyun Jin, Yanrong Chen, Jinbing Bai, Guifen Fu

Acute promyelocytic leukaemia: population-based study of epidemiology and outcome with ATRA and oral-ATO from 1991 to 2021

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Harinder Gill, Radha Raghupathy, Carmen Y.Y. Lee, Yammy Yung, Hiu-Tung Chu, Michael Y. Ni, Xiao Xiao, Francis P. Flores, Rita Yim, Paul Lee, Lynn Chin, Vivian W.K. Li, Lester Au, Wing-Yan Au, Edmond S.K. Ma, Diwakar Mohan, Cyrus Rustam Kumana, Yok-Lam Kwong

MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study

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Yuri Noda, Mitsuaki Ishida, Ryosuke Yamaka, Yasuhiro Ueno, Tomofumi Sakagami, Takuo Fujisawa, Hiroshi Iwai, Koji Tsuta

Efficacy of PD-1/PD-L1 inhibitors in gastric or gastro-oesophageal junction cancer based on clinical characteristics: a meta-analysis

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Gengwei Huo, Wenjie Liu, Peng Chen

Machine learning-based colorectal cancer prediction using global dietary data

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Hanif Abdul Rahman, Mohammad Ashraf Ottom, Ivo D. Dinov

Identification on surrogating overall survival with progression-free survival of first-line immunochemotherapy in advanced esophageal squamous cell carcinoma—an exploration of surrogate endpoint

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Zewei Zhang, Chunxia Xie, Tiantian Gao, Yuxian Yang, Yong Yang, Lei Zhao

TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma

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Ru Zhu, Yu-Ting Chen, Bo-Wen Wang, Ya-Yan You, Xing-Hua Wang, Hua-Tao Xie, Fa-Gang Jiang, Ming-Chang Zhang

Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma

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Areeba Rehman, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Janeen H. Trembley, Naeem Mahmood Ashraf, Tayyaba Afsar, Ali Almajwal, Nawaf W. Alruwaili, Ali Alshamari, Tariq Nahar Alanezi, Suhail Razak

What have we learnt from the past – would treatment decisions for GEP-NET patients differ between 2012 to 2016 by the new recommendations in 2022?

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Rahel Stiefel, Kuno Lehmann, Thomas Winder, Alexander R. Siebenhüner

Colorectal cancer survivors’ long-term recollections of their illness and therapy up to seven years after enrolment into a randomised controlled clinical trial

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Vinzenz Völkel, Brunhilde Steinger, Michael Koller, Monika Klinkhammer-Schalke, Patricia Lindberg-Scharf

CXCL10 is a prognostic marker for pancreatic adenocarcinoma and tumor microenvironment remodeling

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Yuan Nie, Chao Liu, Qi Liu, Xuan Zhu

Clinical impact of tetracyclines and/or proton pump inhibitors on the efficacy of epidermal growth factor receptor inhibitors in non-small cell lung cancer: a retrospective cohort study

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Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Yu-Hung Kuo, Mann-Jen Hour

Identification of four metabolic subtypes and key prognostic markers in lung adenocarcinoma based on glycolytic and glutaminolytic pathways

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Jinjin Zhang, Xiaopeng Wang, Congkuan Song, Qi Li

Single-copy Snail upregulation causes partial epithelial-mesenchymal transition in colon cancer cells

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Fatima Junaid, Goran Tomic, Richard Kemp, Doug J. Winton

Novel fusion protein PK5-RL-Gal-3C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity

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Xiaoge Gao, Pin Jiang, Xiaohuan Wei, Wei Zhang, Jiwei Zheng, Shishuo Sun, Hong Yao, Xiangye Liu, Qing Zhang

Is prior cancer history a hindrance for non-small cell lung cancer patients to participate in clinical trials?

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Jing-Sheng Cai, Yun Li, Xun Wang

The association of healthy lifestyle index score and the risk of renal cell cancer in the Netherlands cohort study

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Romain Meer, Jeroen van de Pol, Piet A. van den Brandt, Leo J. Schouten

CytoSaLPs score: a promising new tool for the detection and screening of extrauterine high grade serous carcinoma

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Sofia Lekka, Victoria Psomiadou, Theodoros Panoskaltsis, Eleni Tsouma, Natasa Novkovic, Helen Trihia, Olympia Tzaida, Dimitrios Korfias, Panagiotis Giannakas, Christos Iavazzo, Panagiotis Vakas, Nikolaos Vlahos, George Vorgias

Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival

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Maha S. Al-Keilani, Roba Bdeir, Rana I. Elstaty, Mohammad A. Alqudah

Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition

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S. G. Yammine, I. Huybrechts, C. Biessy, L. Dossus, S. Panico, M. J. Sánchez, V. Benetou, R. Turzanski-Fortner, V. Katzke, A. Idahl, G. Skeie, K. Standahl Olsen, A. Tjønneland, J. Halkjaer, S. Colorado-Yohar, A. K. Heath, E. Sonestedt, H. Sartor, M. B. Schulze, D. Palli, M. Crous-Bou, A. Dorronsoro, K. Overvad, A. Barricarte Gurrea, G. Severi, R. C.H. Vermeulen, T. M. Sandanger, R. C. Travis, T. Key, P. Amiano, B. Van Guelpen, M. Johansson, M. Sund, R. Tumino, N. Wareham, C. Sacerdote, V. Krogh, P. Brennan, E. Riboli, E. Weiderpass, M. J. Gunter, V. Chajès

Bioinformatics analysis and experimental validation of cuproptosis-related lncRNA LINC02154 in clear cell renal cell carcinoma

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Junlin Shen, Linhui Wang, Jianbin Bi

The clinicopathological significance of thymic epithelial markers expression in thymoma and thymic carcinoma

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Huiyang Li, Bo Ren, Shili Yu, Hongwen Gao, Ping-Li Sun

Screening and identification of miR-181a-5p in oral squamous cell carcinoma and functional verification in vivo and in vitro

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Guoqiang Xu, Yiyan Yang, Junting Yang, Lanfei Xiao, Xiaotang Wang, Litao Qin, Jiping Gao, Ruijing Xuan, Xiaofen Wu, Zhaoyang Chen, Rui Sun, Guohua Song

Developing a predictive nomogram for colposcopists: a retrospective, multicenter study of cervical precancer identification in China

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Peng Xue, Samuel Seery, Sumeng Wang, Yu Jiang, Youlin Qiao

Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

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Tove Selvin, Malin Berglund, Lena Lenhammar, Malin Jarvius, Peter Nygren, Mårten Fryknäs, Rolf Larsson, Claes R Andersson

Analysis of risk characteristics for metachronous metastasis in different period of nasopharyngeal carcinoma

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Zhaodong Fei, Huiling Hong, Ting Xu, Yiying Xu, Jiawei Chen, Xiufang Qiu, Jianming Ding, Ye Feng, Chaoxiong Huang, Li Li, Mengying Li, Chuanben Chen

Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma

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Alessia Visconti, Niccolò Rossi, Helena Deriš, Karla A Lee, Maja Hanić, Irena Trbojević-Akmačić, Andrew M. Thomas, Laura A. Bolte, Johannes R. Björk, Jahlisa S. Hooiveld-Noeken, Ruth Board, Mark Harland, Julia Newton-Bishop, Mark Harries, Joseph J. Sacco, Paul Lorigan, Heather M. Shaw, Elisabeth G.E. de Vries, Rudolf S.N. Fehrmann, Rinse K. Weersma, Tim D. Spector, Paul Nathan, Geke A. P. Hospers, Peter Sasieni, Veronique Bataille, Gordan Lauc, Mario Falchi

Enhanced antitumor activity of a novel, oral, helper epitope-containing WT1 protein vaccine in a model of murine leukemia

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Hikaru Minagawa, Yoshiko Hashii, Hiroko Nakajima, Fumihiro Fujiki, Soyoko Morimoto, Jun Nakata, Toshiro Shirakawa, Takane Katayama, Akihiro Tsuboi, Keiichi Ozono

Promoter hypermethylation analysis of host genes in cervical intraepithelial neoplasia and cervical cancers on histological cervical specimens

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Liye Shi, Xue Yang, Ling He, Chunying Zheng, Zhen Ren, Juweria Abdisamad Warsame, Suye Suye, Lei Yan, Haiyi Cai, Xiao Xiao, Chun Fu

Cytoplasmic poly(A)-binding protein 1 (PABPC1) is a prognostic biomarker to predict survival in nasopharyngeal carcinoma regardless of chemoradiotherapy

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Feng Ling, Shengen Xu, Xiaochen Li, Xingwang Sun, Wenbo Long

Fibroblast growth factor receptor type 4 as a potential therapeutic target in clear cell renal cell carcinoma

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Takafumi Narisawa, Sei Naito, Hiromi Ito, Osamu Ichiyanagi, Toshihiko Sakurai, Tomoyuki Kato, Norihiko Tsuchiya

An observational study of dose dense chemotherapy with lipegfilgrastim support in early breast cancer

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Ahmed Rashed, Orla M Fitzpatrick, David J Easty, Zac Coyne, Dearbhaile Collins, Victoria Mallet, Maciej Milewski, Keith Egan, Oscar S Breathnach, Liam Grogan, Bryan T Hennessy, Patrick G Morris

Dishevelled 2 regulates cancer cell proliferation and T cell mediated immunity in HER2-positive breast cancer

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Fahmida Rasha, Geetha Priya Boligala, Mingxiao V. Yang, Dalia Martinez-Marin, Isabel Castro-Piedras, Kathryn Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Maribel Castro, Hafiz Khan, Nusrat Jahan, Sharilyn Almodovar, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman

Distribution, dynamic evolution, and clinical outcomes of patients with advanced breast cancer according to HER2 expression

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Qin Shi, Jing Yu, Deyue Liu, Fang Ren, Jiayi Wu, Kunwei Shen

Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy

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Agathe Quesnel, Nathan Coles, Claudio Angione, Priyanka Dey, Tuomo M. Polvikoski, Tiago F. Outeiro, Meez Islam, Ahmad A. Khundakar, Panagiota S. Filippou

Biochemical and pathophysiological improvements in rats with thioacetamide induced-hepatocellular carcinoma using aspirin plus vitamin C

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Rana R. El Sadda, Zahraa R. Elshahawy, Entsar A. Saad

MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR

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Xiaowei Chang, Chang Tian, Yuanyuan Jia, Yu Cai, Pu Yan

FOLFOX regimen after failure of fluorouracil and leucovorin plus nanoliposomal-irinotecan therapy for advanced pancreatic cancer: a retrospective observational study

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Satoshi Kobayashi, Shun Tezuka, Yui Yamachika, Shotaro Tsunoda, Shuhei Nagashima, Yuichiro Tozuka, Taito Fukushima, Manabu Morimoto, Makoto Ueno, Junji Furuse, Shin Maeda

Is obesity a risk factor for melanoma?

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Yuval Arbel, Yifat Arbel, Amichai Kerner, Miryam Kerner

FANCD2 inhibits ferroptosis by regulating the JAK2/STAT3 pathway in osteosarcoma

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Xujun Li, Jiangyi Liu

INTEGRATE II: randomised phase III controlled trials of regorafenib containing regimens versus standard of care in refractory Advanced Gastro-Oesophageal Cancer (AGOC): a study by the Australasian Gastro-Intestinal Trials Group (AGITG)

• Open Access
• Study Protocol

Lyn Ley Lam, Nick Pavlakis, Kohei Shitara, Katrin M. Sjoquist, Andrew J. Martin, Sonia Yip, Yoon-Koo Kang, Yung-Jue Bang, Li-Tzong Chen, Markus Moehler, Tanios Bekaii-Saab, Thierry Alcindor, Christopher J. O’Callaghan, Niall C. Tebbutt, Wendy Hague, Howard Chan, Sun Young Rha, Keun-Wook Lee, Val Gebski, Anthony Jaworski, John Zalcberg, Timothy Price, John Simes, David Goldstein

Identification and verification of a BMPs-related gene signature for osteosarcoma prognosis prediction

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Long Xie, Jiaxing Zeng, Maolin He

ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling – a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial

• Open Access
• Study Protocol

Tina Kringelbach, Martin Højgaard, Kristoffer Rohrberg, Iben Spanggaard, Britt Elmedal Laursen, Morten Ladekarl, Charlotte Aaquist Haslund, Laurine Harsløf, Laila Belcaid, Julie Gehl, Lise Søndergaard, Rikke Løvendahl Eefsen, Karin Holmskov Hansen, Annette Raskov Kodahl, Lars Henrik Jensen, Marianne Ingerslev Holt, Trine Heide Oellegaard, Christina Westmose Yde, Lise Barlebo Ahlborn, Ulrik Lassen

A metabolome-wide case-control study of african american breast cancer patients

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Jiajun Luo, Muhammad G. Kibriya, Hui Chen, Karen Kim, Habibul Ahsan, Olufunmilayo I. Olopade, Christopher S. Olopade, Briseis Aschebrook-Kilfoy, Dezheng Huo

Peripheral immune cell profiling of double-hit lymphoma by mass cytometry

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Tao Lei, Gongqiang Wu, Yongjin Xu, Weihao Zhuang, Jialiang Lu, Shuiyun Han, Yuxin Zhuang, Xiaowu Dong, Haiyan Yang

Characteristics of vasculogenic mimicry and tumour to endothelial transdifferentiation in human glioblastoma: a systematic review

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Kelsey Maddison, Nikola A. Bowden, Moira C. Graves, Paul A. Tooney

Global retrospective analysis of clinician- and patient-reported clinical characteristics and humanistic burden of patients with gastroesophageal cancers on first-line treatment

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Hong Xiao, David Bertwistle, Keerun Khela, Chloe Middleton-Dalby, Jennifer Hall

Colposcopic accuracy in diagnosing squamous intraepithelial lesions: a systematic review and meta-analysis of the International Federation of Cervical Pathology and Colposcopy 2011 terminology

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Dongxu Qin, Anying Bai, Peng Xue, Samuel Seery, Jiaxu Wang, Maria Jose Gonzalez Mendez, Qing Li, Yu Jiang, Youlin Qiao

A novel preoperative inflammation score system established for postoperative prognosis predicting of intrahepatic cholangiocarcinoma

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Jun Fu, Qinjunjie Chen, Zisen Lai, Kongying Lin, Guoxu Fang, Zongren Ding, Yuzhen Gao, Yongyi Zeng

Construction of a radiogenomic association map of pancreatic ductal adenocarcinoma

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Neema Jamshidi, Jayasuriya Senthilvelan, David W. Dawson, Timothy R. Donahue, Michael D. Kuo

Correction: Cytoplasmic poly(A)-binding protein 1 (PABPC1) is a prognostic biomarker to predict survival in nasopharyngeal carcinoma regardless of chemoradiotherapy

• Open Access
• Correction

Feng Ling, Shengen Xu, Xiaochen Li, Xingwang Sun, Wenbo Long

Survival comparison of first-line treatment regimens in patients with braf-mutated advanced colorectal cancer: a multicenter retrospective study

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Qianhao Meng, Jian Zhao, Yuanyuan Yu, Ke Wang, Jing Ren, Chang Xu, Yusheng Wang, Guangyu Wang

Correction: Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy

• Open Access
• Correction

Cengiz Karacin, Berna Oksuzoglu, Ayşe Demirci, Merve Keskinkılıç, Naziyet Köse Baytemür, Funda Yılmaz, Oğuzhan Selvi, Dilek Erdem, Esin Avşar, Nail Paksoy, Necla Demir, Sema Sezgin Göksu, Sema Türker, Ertuğrul Bayram, Abdüssamet Çelebi, Hatice Yılmaz, Ömer Faruk Kuzu, Seda Kahraman, İvo Gökmen, Abdullah Sakin, Ali Alkan, Erdinç Nayır, Muzafer Uğraklı, Ömer Acar, İsmail Ertürk, Hacer Demir, Ferit Aslan, Özlem Sönmez, Taner Korkmaz, Özde Melisa Celayir, İbrahim Karadağ, Erkan Kayıkçıoğlu, Teoman Şakalar, İlker Nihat Öktem, Tülay Eren, Enes Erul, Eda Eylemer Mocan, Ziya Kalkan, Nilgün Yıldırım, Yakup Ergün, Baran Akagündüz, Serdar Karakaya, Engin Kut, Fatih Teker, Burçin Çakan Demirel, Kubilay Karaboyun, Elvina Almuradova, Olçun Ümit Ünal, Abdilkerim Oyman, Deniz Işık, Kerem Okutur, Buğra Öztosun, Burcu Belen Gülbağcı, Mehmet Emin Kalender, Elif Şahin, Mustafa Seyyar, Özlem Özdemir, Fatih Selçukbiricik, Metin Kanıtez, İsa Dede, Mahmut Gümüş, Erhan Gökmen, Arzu Yaren, Serkan Menekşe, Senar Ebinç, Sercan Aksoy, Gökşen İnanç İmamoğlu, Mustafa Altınbaş, Bülent Çetin, Başak Oyan Uluç, Özlem Er, Nuri Karadurmuş, Atike Pınar Erdoğan, Mehmet Artaç, Özgür Tanrıverdi, İrfan Çiçin, Mehmet Ali Nahit Şendur, Esin Oktay, İbrahim Vedat Bayoğlu, Semra Paydaş, Adnan Aydıner, Derya Kıvrak Salim, Çağlayan Geredeli, Tuğba Yavuzşen, Mutlu Doğan, İlhan Hacıbekiroğlu

An integrated strategy for deciding open versus laparoscopic hepatectomy for resectable primary liver cancer

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Yizhen Fu, Zhenyun Yang, Zili Hu, Zhoutian Yang, Jinbin Chen, Juncheng Wang, Zhongguo Zhou, Li Xu, Minshan Chen, Yaojun Zhang

Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy

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Xiashuang Zhao, Yongfeng Wang, Xianglai Jiang, Bangqian Mo, Chenyu Wang, Mingzheng Tang, Yao Rong, Guiqian Zhang, Ming Hu, Hui Cai

Screening of prognosis-related Immune cells and prognostic predictors in Colorectal Cancer Patients

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Shuangshuang Deng, Qiping Zhu, Hongyan Chen, Tianyu Xiao, Yinshen Zhu, Jinli Gao, Qing Li, Yong Gao

One year overall survival of wilms tumor cases and its predictors, among children diagnosed at a teaching hospital in South Western Uganda: a retrospective cohort study

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Eddymond Ekuk, Charles Newton Odongo, Leevan Tibaijuka, Felix Oyania, Walufu Ivan Egesa, Felix Bongomin, Raymond Atwiine, Moses Acan, Martin Situma

Machine learning to predict occult metastatic lymph nodes along the recurrent laryngeal nerves in thoracic esophageal squamous cell carcinoma

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Yiliang Zhang, Longfu Zhang, Bin Li, Ting Ye, Yang Zhang, Yongfu Yu, Yuan Ma, Yihua Sun, Jiaqing Xiang, Yike Li, Haiquan Chen

Optimal therapy for concomitant EGFR and TP53 mutated non-small cell lung cancer: a real-world study

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Haiyan Sun, Peng Ren, Yongzi Chen, Lan Lan, Zhuchen Yan, Yinli Yang, Bin Wang, Cong Wang, Yanwei Li, Ling Li, Yu Zhang, Yanyang Li, Zuolin Wang, Zhanyu Pan, Zhansheng Jiang

Integrated transcriptional analysis reveals macrophage heterogeneity and macrophage-tumor cell interactions in the progression of pancreatic ductal adenocarcinoma

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Kaidi Yang, Tongxin Yang, Jian Yu, Fang Li, Xiang Zhao

Effect of a 1-year tailored exercise program according to cancer trajectories in patients with breast cancer: study protocol for a randomized controlled trial

• Open Access
• Study Protocol

Jiin Ryu, Eun-Young Lee, Jihee Min, Sujin Yeon, Ji-Won Lee, Sang Hui Chu, Hyangkyu Lee, Seung Il Kim, Jee Ye Kim, Seho Park, Justin Y. Jeon

CT texture analysis in predicting treatment response and survival in patients with hepatocellular carcinoma treated with transarterial chemoembolization using random forest models

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He An, Inderjeet Bhatia, Fei Cao, Zilin Huang, Chuanmiao Xie

MicroRNA-125b as a valuable predictive marker for outcome after autologous hematopoietic stem cell transplantation

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Mohammad Rafiee, Fatemeh Amiri, Mohammad Hossein Mohammadi, Abbas Hajifathali

Clinical characteristics and therapeutic effects of checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer

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Li Pang, Mei Xie, Xidong Ma, Aiben Huang, Jialin Song, Jie Yao, Hui Deng, Duchao Zhang, Xuelei Zang, Fangping Ren, Jie Gao, Chongchong Wu, Yuanyong Wang, Xin Zhang, Xinyu Bao, Lei Pan, Xinying Xue

Assessment of Autologous Blood marker localIzation and intraoperative coLonoscopy localIzation in laparoscopic colorecTal cancer surgery (ABILITY): a randomized controlled trial

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• Study protocol

Ke-hui Zhang, Jing-ze Li, Hai-bin Zhang, Ren-hao Hu, Xi-mao Cui, Tao Du, Liang Zheng, Shun Zhang, Chun Song, Mei-dong Xu, Xiao-hua Jiang

Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours

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Birgit S. Geurts, Thomas W. Battaglia, J. Maxime van Berge Henegouwen, Laurien J. Zeverijn, Gijs F. de Wit, Louisa R. Hoes, Hanneke van der Wijngaart, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Frans L. Opdam, Maja J. A. de Jonge, Geert A. Cirkel, Mariette Labots, Ann Hoeben, Emile D. Kerver, Adriaan D. Bins, Frans G.L. Erdkamp, Johan M. van Rooijen, Danny Houtsma, Mathijs P. Hendriks, Jan-Willem B. de Groot, Henk M. W. Verheul, Hans Gelderblom, Emile E. Voest

Intracranial efficacy and safety of furmonertinib 160 mg with or without anti-angiogenic agent in advanced NSCLC patients with BM/LM as salvage therapy

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Ziyi Xu, Xuezhi Hao, Qi Wang, Ke Yang, Junling Li, Puyuan Xing

Raltitrexed enhanced antitumor effect of anlotinib in human esophageal squamous carcinoma cells on proliferation, invasiveness, and apoptosis

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Hongchao Zhen, Jizheng Tian, Guangxin Li, Pengfei Zhao, Ying Zhang, Juanjuan Che, Bangwei Cao

Dyslipidemia is associated with a poor prognosis of breast cancer in patients receiving neoadjuvant chemotherapy

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Youzhao Ma, Minhao Lv, Peng Yuan, Xiuchun Chen, Zhenzhen Liu

Phase II clinical trial of sequential treatment with systemic chemotherapy and intraperitoneal paclitaxel for gastric and gastroesophageal junction peritoneal carcinomatosis - STOPGAP trial

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Maheswari Senthil, Farshid Dayyani

Electrocardiographic and biochemical analysis of anthracycline induced cardiotoxicity in breast cancer patients from Southern Sri Lanka

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Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam, Madappuli Arachchige Chaminda Sri Sampath Fernando, Kamani Ayoma Perera Wijewardana Jayatilaka

Sintilimab Plus Apatinib and Chemotherapy as Second‑/Third-Line treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a prospective, Single-Arm, phase II trial

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Le Zhang, Weixue Wang, Shaohua Ge, Hongli Li, Ming Bai, Jingjing Duan, Yuchong Yang, Tao Ning, Rui Liu, Xia Wang, Zhi Ji, Feixue Wang, Haiyang Zhang, Yi Ba, Ting Deng

Sarcopenia negatively affects postoperative short-term outcomes of patients with non-cirrhosis liver cancer

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Jinhuan Yang, Daojie Wang, Lei Ma, Xuewen An, Zijing Hu, Huili Zhu, Wanqian Zhang, Kaiwen Chen, Jun Ma, Yan Yang, Lijun Wu, Gang Chen, Yi Wang

Incidence trends of oral cavity, oropharyngeal, hypopharyngeal and laryngeal cancers among males in Taiwan, 1980–2019: a population-based cancer registry study

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Yu-Shiun Tsai, Yong-Chen Chen, Tzu-I Chen, Yu-Kwang Lee, Chun-Ju Chiang, San-Lin You, Wan-Lun Hsu, Li-Jen Liao

Development and validation of a survival nomogram and calculator for male patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate and/or enzalutamide

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Takashi Kawahara, Yusuke Saigusa, Shuko Yoneyama, Masashi Kato, Ippei Kojima, Hiroshi Yamada, Osamu Kamihira, Kenichi Tabata, Hideyasu Tsumura, Masatsugu Iwamura, Kazuhide Makiyama, Hiroji Uemura, Yasuhide Miyoshi

Stereotactic ablative body radiotherapy with a central high dose using CyberKnife for metastatic lung tumors

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Kazuhiko Hayashi, Osamu Suzuki, Hiroya Shiomi, Hitoshi Ono, Akira Setoguchi, Masataka Nakai, Erina Nakanishi, Shotaro Tatekawa, Naoko Ose, Takero Hirata, Keisuke Tamari, Yuji Seo, Soichiro Funaki, Fumiaki Isohashi, Shinichi Shimizu, Yasushi Shintani, Kazuhiko Ogawa

Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression

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Sarah A Cain, Bernard Pope, Stefano Mangiola, Theo Mantamadiotis, Katharine J Drummond

Clinicopathological and mutational characteristics of primary double mutant gastrointestinal stromal tumor: a single center study with review of the literature

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Jiaqi Yan, Xin He, Chaoyong Shen, Yan Zou, Huijiao Chen, Yuan Tang

Evaluating prognostic value and stage migration effects using a positive lymph node ratio in adenocarcinoma of the esophagogastric junction

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Hajime Kamiya, Shuhei Komatsu, Keiji Nishibeppu, Takuma Ohashi, Hirotaka Konishi, Atsushi Shiozaki, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji

Protocol for the 2ND-STEP study, Japan Clinical Oncology Group study JCOG1802: a randomized phase II trial of second-line treatment for advanced soft tissue sarcoma comparing trabectedin, eribulin and pazopanib

• Open Access
• Study Protocol

Makoto Endo, Tomoko Kataoka, Toshifumi Fujiwara, Satoshi Tsukushi, Masanobu Takahashi, Eisuke Kobayashi, Yoko Yamada, Takaaki Tanaka, Yutaka Nezu, Hiroaki Hiraga, Junji Wasa, Akihito Nagano, Kenji Nakano, Robert Nakayama, Tetsuya Hamada, Masanori Kawano, Tomoaki Torigoe, Akio Sakamoto, Kunihiro Asanuma, Takeshi Morii, Ryunosuke Machida, Yuta Sekino, Haruhiko Fukuda, Yoshinao Oda, Toshifumi Ozaki, Kazuhiro Tanaka

Spatial characterization and quantification of CD40 expression across cancer types

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Katherine M. Bates, Ioannis Vathiotis, Tyler MacNeil, Fahad Shabbir Ahmed, Thazin Nwe Aung, Yuliya Katlinskaya, Sabyasachi Bhattacharya, Amanda Psyrri, Steven Yea, Amanda Parkes, Nooshin Hashemi Sadraei, Siddhartha Roychoudhury, David L. Rimm, Niki Gavrielatou

Characterisation of tumor microenvironment and prevalence of CD274/PD-L1 genetic alterations difference in colorectal Cancer

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Lin Yang, Shousheng Liu, Wenzhuo He, Zhenchong Xiong, Liangping Xia

The hsa_circ_0000276-ceRNA regulatory network and immune infiltration in cervical cancer

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Honglei Zhang, Xiuting Wang, Yaqin Li, Ying Bai, Qi Li, Shuling Wang, Yimiao Wei, Jiarong Li, Songquan Wen, Weihong Zhao

ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies

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Marion Perréard, Romane Florent, Jordane Divoux, Jean-Michel Grellard, Justine Lequesne, Mélanie Briand, Bénédicte Clarisse, Nathalie Rousseau, Esther Lebreton, Brice Dubois, Valentin Harter, Audrey Lasne-Cardon, Julien Drouet, Alisson Johnson, Anne-Laure Le Page, Céline Bazille, Corinne Jeanne, Martin Figeac, Nicolas Goardon, Dominique Vaur, Emmanuel Micault, Maxime Humbert, Juliette Thariat, Emmanuel Babin, Laurent Poulain, Louis-Bastien Weiswald, Vianney Bastit

Impact of oral statin therapy on clinical outcomes in patients with cT1 breast cancer

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Koji Takada, Shinichiro Kashiwagi, Nozomi Iimori, Rika Kouhashi, Akimichi Yabumoto, Wataru Goto, Yuka Asano, Yukie Tauchi, Tamami Morisaki, Kana Ogisawa, Masatsune Shibutani, Hiroaki Tanaka, Kiyoshi Maeda

Controlling Nutritional Status (CONUT) score is a prognostic marker in III-IV NSCLC patients receiving first-line chemotherapy

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Yi Zhang, Fei-Fei Kong, Zheng-Qiu Zhu, Hai-Xia Shan

A novel cuproptosis-related gene model predicts outcomes and treatment responses in pancreatic adenocarcinoma

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Qixian Liu, Ruiyu Li, Huanwen Wu, Zhiyong Liang

Diagnostic value of combining preoperative inflammatory markers ratios with CA199 for patients with early-stage pancreatic cancer

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Yuanlong Gu, Qianjin Hua, Zhipeng Li, Xingli Zhang, Changjie Lou, Yangfen Zhang, Wei Wang, Peiyuan Cai, Juan Zhao

The influence of socioeconomic aspects and hospital case volume on survival in colorectal cancer in Saxony, Germany

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Andreas Bogner, Jürgen Weitz, Daniela Piontek

Clinical significance and immune landscape of a novel ferroptosis-related prognosis signature in osteosarcoma

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Liyu Yang, Jiamei Liu, Shengye Liu

Advancing preclinical cancer models to assess clinically relevant outcomes

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• Editorial

Anna Golebiewska, Ryan C. Fields

Patient-guided dose reduction of tyrosine kinase inhibitors in chronic myeloid leukaemia (RODEO study): study protocol for a prospective, multicentre, single-arm trial

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• Study Protocol

Melissa F Djodikromo, Rosella PMG Hermens, Bart JF van den Bemt, Yolba Smit, Tim M Govers, Charlotte L Bekker, Nicole MA Blijlevens

Analysis of connexin 43, connexin 45 and N-cadherin in the human sertoli cell line FS1 and the human seminoma-like cell line TCam-2 in comparison with human testicular biopsies

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Birte Schulz, Valérie Schumacher, Anaclet Ngezahayo, Daniela Maier-Begandt, Nadine Schadzek, Jochen Wilhelm, Wolfgang Weidner, Adrian Pilatz, Daniela Fietz, Sabine Kliesch, Nadine Schnepel, Nina Hambruch, Kristina Rode, Marion Langeheine, Ralph Brehm

Fragment length profiles of cancer mutations enhance detection of circulating tumor DNA in patients with early-stage hepatocellular carcinoma

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Van-Chu Nguyen, Trong Hieu Nguyen, Thanh Hai Phan, Thanh-Huong Thi Tran, Thu Thuy Thi Pham, Tan Dat Ho, Hue Hanh Thi Nguyen, Minh-Long Duong, Cao Minh Nguyen, Que-Tran Bui Nguyen, Hoai-Phuong Thi Bach, Van-Vu Kim, The-Anh Pham, Bao Toan Nguyen, Thanh Nhan Vo Nguyen, Le Anh Khoa Huynh, Vu Uyen Tran, Thuy Thi Thu Tran, Thanh Dang Nguyen, Dung Thai Bieu Phu, Boi Hoan Huu Phan, Quynh-Tho Thi Nguyen, Dinh-Kiet Truong, Thanh-Thuy Thi Do, Hoai-Nghia Nguyen, Minh-Duy Phan, Hoa Giang, Le Son Tran

Monitoring of T790M in plasma ctDNA of advanced EGFR-mutant NSCLC patients on first- or second-generation tyrosine kinase inhibitors

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Chun-Ta Huang, Chih-An Lin, Te-Jen Su, Ching-Yao Yang, Tzu-Hsiu Tsai, Chia-Lin Hsu, Wei-Yu Liao, Kuan-Yu Chen, Chao-Chi Ho, Chong-Jen Yu

TACE versus TACE + entecavir versus TACE + tenofovir in the treatment of HBV associated hepatocellular carcinoma

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Haohao Lu, Chuansheng Zheng, Bin Xiong, Xiangwen Xia

Prognostic significance of the CRAFITY score in hepatocellular carcinoma treated with immunotherapy: a systematic review and meta-analysis

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Ming Yang, Yilin Pan, Wentao Wang

A novel cuproptosis-related gene signature to predict prognosis in Glioma

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Mengyang Zhang, Xiaobai Liu, Di Wang, Xuelei Ruan, Ping Wang, Libo Liu, Yixue Xue

Impact of glucocorticoids on the efficacy of neoadjuvant chemoradiotherapy and survival of patients with locally advanced rectal cancer: a retrospective study

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Xiaoxue Huang, Zhiyuan Zheng, Bangwei Zeng, Han Xiao, Hao Zheng, Zhuangbin Lin, Jianyuan Song, Anchuan Li, Pan Chi, Yinghong Yang, Benhua Xu, Rong Zheng

Clinicomics-guided distant metastasis prediction in breast cancer via artificial intelligence

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Chao Zhang, Lisha Qi, Jun Cai, Haixiao Wu, Yao Xu, Yile Lin, Zhijun Li, Vladimir P. Chekhonin, Karl Peltzer, Manqing Cao, Zhuming Yin, Xin Wang, Wenjuan Ma

Application value of Ki67 and serum CA125 in the deep myometrial invasion of endometrial adenocarcinoma

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Lin Qin

Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinoma

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Junfeng Huang, Bingqi Hu, Ying Yang, Huanhuan Liu, Xingyu Fan, Jing Zhou, Liwen Chen

Plasma exosome-derived connexin43 as a promising biomarker for melanoma patients

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Yue Shen, Ming Li, Li Liao, Suyue Gao, Yongzhen Wang

Clinical characteristics and prognostic characterization of endometrial carcinoma: a comparative analysis of molecular typing protocols

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Zihui Yang, Xi Yang, Xinyu Liu, Ke Ma, Yi-Ting Meng, Hong-Fang Yin, Jia Wen, Jiang-Hui Yang, Zeng Zhen, Zong-Hao Feng, Qin-Ping Liao

The expression, immune infiltration, prognosis, and experimental validation of OSBPL family genes in liver cancer

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Kunpeng Tian, Yongling Ying, Jingjing Huang, Hao Wu, Chengyue Wei, Liang Li, Longjun Chen, Lichuan Wu

A nomogram based on platelet-to-lymphocyte ratio for predicting pathological complete response of breast cancer after neoadjuvant chemotherapy

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Rulan Ma, Wanzhen Wei, Haixia Ye, Chengxue Dang, Kang Li, Dawei Yuan

RETRACTED ARTICLE: Effect of neoadjuvant chemotherapy combined with arterial chemoembolization on short-term clinical outcome of locally advanced gastric cancer

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Jianguo Yang, Juncai Li, Qican Deng, Zhenzhou Chen, Kuan He, Yajun Chen, Zhongxue Fu

A text-mining approach to study the real-world effectiveness and potentially fatal immune-related adverse events of PD-1 and PD-L1 inhibitors in older patients with stage III/IV non-small cell lung cancer

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Hanieh Abedian Kalkhoran, Juliëtte Zwaveling, Bert N. Storm, Sylvia A. van Laar, Johanneke EA Portielje, Henk Codrington, Dieuwke Luijten, Pepijn Brocken, Egbert F. Smit, Loes E. Visser

Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma

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Masaoki Ito, Yoshihiro Miyata, Kei Kushitani, Daisuke Ueda, Yukio Takeshima, Morihito Okada

Neoadjuvant chemoradiotherapy plus tislelizumab followed by surgery for esophageal carcinoma (CRISEC study): the protocol of a prospective, single-arm, phase II trial

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• Study protocol

Jinsong Yang, Ai Huang, Kunyu Yang, Ke Jiang

Pre-diagnostic anti-EBV antibodies and primary liver cancer risk: a population-based nested case-control study in southern China

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Yun Du, Xia Yu, Ellen T. Chang, Shifeng Lian, Biaohua Wu, Fugui Li, Bing Chu, Kuangrong Wei, Jiyun Zhan, Xuejun Liang, Weimin Ye, Mingfang Ji

Granulocyte-colony stimulating factor does not prevent in vitro cisplatin-induced germ cell reduction in immature human and mouse testis

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• Research article

Gabriele Matilionyte, Grace Forsyth, Jingtao Guo, Michael P. Rimmer, Brian P. Hermann, Richard A. Anderson, Rod T. Mitchell

Relationship between tumor microbiota transcriptional activity and gene expression in breast cancer

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Enuo Liu, Fan Zhang, Tiansheng Xu, Luyi Ye, Sean Si Qian Ma, Zai-Si Ji

Clinical outcomes in patients with solid tumors living in rural and urban areas followed via telemedicine: experience in a highly complex latin american hospital

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Juan Guillermo Restrepo, Juliana Alarcón, Andrés Hernández, Saveria Sangiovanni, Sofía González, Kelly Gallego, Evelyn E. Peña-Zárate, Laura Libreros-Peña, María Fernanda Escobar

Association of neutrophil–lymphocyte ratio with survival in peripheral early-stage non-small cell lung cancer after stereotactic body radiation therapy

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Karen Huang, Sharan Prasad, Sung Jun Ma, Han Yu, Austin J. Iovoli, Mark K. Farrugia, Elizabeth U. Dexter, Todd L. Demmy, Nadia K. Malik, Anurag K. Singh

DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells

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• Research article

Weijing Li, Shuguang Liu, Chanjuan Wang, Lei Cui, Xiaoxi Zhao, Wei Liu, Ruidong Zhang, Zhigang Li

Association of smoking, alcohol, and coffee consumption with the risk of ovarian cancer and prognosis: a mendelian randomization study

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Sicong Liu, Songwei Feng, Furong Du, Ke Zhang, Yang Shen

ctDNA guided adjuvant chemotherapy versus standard of care adjuvant chemotherapy after curative surgery in patients with high risk stage II or stage III colorectal cancer: a multi-centre, prospective, randomised control trial (TRACC Part C)

• Open Access
• Study Protocol

Susanna Slater, Annette Bryant, Hsiang-Chi Chen, Ruwaida Begum, Isma Rana, Maria Aresu, Clare Peckitt, Oleg Zhitkov, Retchel Lazaro-Alcausi, Victoria Borja, Rachel Powell, David Lowery, Michael Hubank, Thereasa Rich, Gayathri Anandappa, Ian Chau, Naureen Starling, David Cunningham

TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression

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Haodong Wang, Huaiping Cui, Xinjun Yang, Lipan Peng

Interaction between PD-L1 and soluble VEGFR1 in glioblastoma-educated macrophages

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Xin Liu, Zhenke Li, Jinxing Sun, Zhijie Zhang, Weiguo Li

Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study

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Yan Wang, Lili Du, Jiexian Jing, Xianwen Zhao, Xing Wang, Shenghuai Hou

Radiomics nomogram for preoperative differentiation of pulmonary mucinous adenocarcinoma from tuberculoma in solitary pulmonary solid nodules

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Junjie Zhang, Ligang Hao, MingWei Qi, Qian Xu, Ning Zhang, Hui Feng, Gaofeng Shi

Feasibility and preliminary efficacy of a virtual reality intervention targeting distress and anxiety in primary brain tumor patients at the time of clinical evaluation: Study protocol for a phase 2 clinical trial

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• Study Protocol

Amanda L. King, Alvina A. Acquaye-Mallory, Elizabeth Vera, Tito Mendoza, Jennifer Reyes, Macy L. Stockdill, Mark R. Gilbert, Terri S. Armstrong

Identification of ZBTB4 as an immunological biomarker that can inhibit the proliferation and invasion of pancreatic cancer

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Zhe Yang, Feiran Chen, Feng Wang, Xiubing Chen, Biaolin Zheng, Xiaomin Liao, Zhejun Deng, Xianxian Ruan, Jing Ning, Qing Li, Haixing Jiang, Shanyu Qin

Comprehensive analyses of A 12-metabolism-associated gene signature and its connection with tumor metastases in clear cell renal cell carcinoma

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Diaoyi Tan, Daojia Miao, Chuanyi Zhao, Jian Shi, Qingyang Lv, Zhiyong Xiong, Hongmei Yang, Xiaoping Zhang

Impact of COVID-19 in patients on active melanoma therapy and with history of melanoma

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Douglas B. Johnson, Michael B. Atkins, Cassandra Hennessy, Trisha Wise-Draper, Hannah Heilman, Joy Awosika, Ziad Bakouny, Chris Labaki, Renee Maria Saliby, Clara Hwang, Sunny R. K. Singh, Nino Balanchivadze, Christopher R. Friese, Leslie A. Fecher, James J. Yoon, Brandon Hayes-Lattin, Mehmet A. Bilen, Cecilia A. Castellano, Gary H. Lyman, Lisa Tachiki, Sumit A. Shah, Michael J. Glover, Daniel B. Flora, Elizabeth Wulff-Burchfield, Anup Kasi, Saqib H. Abbasi, Dimitrios Farmakiotis, Kendra Viera, Elizabeth J. Klein, Lisa B. Weissman, Chinmay Jani, Matthew Puc, Catherine C. Fahey, Daniel Y. Reuben, Sanjay Mishra, Alicia Beeghly-Fadiel, Benjamin French, Jeremy L. Warner, Sonya A. Reid, Alaina J. Brown, Alex Cheng, Sarah Croessmann, Elizabeth J. Davis, Kyle T. Enriquez, Erin A. Gillaspie, Daniel Hausrath, Xuanyi Li, David A. Slosky, Carmen C. Solorzano, Matthew D. Tucker, Karen Vega-Luna, Lucy L. Wang, Trisha M. Wise-Draper, Syed A. Ahmad, Punita Grover, Shuchi Gulati, Jordan Kharofa, Tahir Latif, Michelle Marcum, Davendra P. S. Sohal, Olga Zamulko, Toni K. Choueiri, Jean M. Connors, George D. Demetri, Narjust Duma, Dory A. Freeman, Antonio Giordano, Alicia K. Morgans, Anju Nohria, Renee-Maria Saliby, Andrew L. Schmidt, Eliezer M. Van Allen, Wenxin Xu, Rebecca L. Zon, Shirish M. Gadgeel, Sheela Tejwani, Anne Boldt, Aaron M. Cohen, Shannon McWeeney, Eneida R. Nemecek, Staci P. Williamson, Deepak Ravindranathan, Jerome J. Graber, Petros Grivas, Jessica E. Hawley, Elizabeth T. Loggers, Ryan C. Lynch, Elizabeth S. Nakasone, Michael T. Schweizer, Shaveta Vinayak, Michael J. Wagner, Albert Yeh, Elwyn C. Cabebe, Michael J. Glover, Alokkumar Jha, Ali Raza Khaki, Lidia Schapira, Julie Tsu-Yu Wu, Goetz Kloecker, Barbara B. Logan, Chaitanya Mandapakala, Crosby D. Rock, Panos Arvanitis, Pamela C. Egan, Hina Khan, Adam J. Olszewski, Kendra Vieira, Lisa B. Weissmann, Padmanabh S. Bhatt, Melissa G. Mariano, Carey C. Thomson, Theresa M. Carducci, Karen J. Goldsmith, Susan Van Loon, Mariam Alexander, Sara Matar, Sarah Mushtaq, Keith E. Stockerl-Goldstein, Omar Butt, Mark A. Fiala, Jeffrey P. Henderson, Ryan S. Monahan, Alice Y. Zhou, Philip E. Lammers, Sanjay G. Revankar, Salvatore A. Del Prete, Michael H. Bar, Anthony P. Gulati, K. M. Steve Lo, Suzanne J. Rose, Jamie Stratton, Paul L. Weinstein, Shilpa Gupta, Nathan A. Pennell, Manmeet S. Ahluwalia, Scott J. Dawsey, Christopher A. Lemmon, Amanda Nizam, Nima Sharifi, Claire Hoppenot, Ang Li, Susan Halabi, Hannah Dzimitrowicz, Tian Zhang, Sharad Goyal, Minh-Phuong Huynh-Le, Peter Paul Yu, Jessica M. Clement, Ahmad Daher, Mark E. Dailey, Rawad Elias, Asha Jayaraj, Emily Hsu, Alvaro G. Menendez, Oscar K. Serrano, Melissa K. Accordino, Divaya Bhutani, Dawn Hershman, Matthew A. Ingham, Gary K. Schwartz, Eric H. Bernicker, John F. Deeken, Danielle Shafer, Erika Ruíz-García, Ana Ramirez, Diana Vilar-Compte, Mark A. Lewis, Terence D. Rhodes, David M. Gill, Clarke A. Low, Sandeep H. Mashru, Abdul-Hai Mansoor, Grant C. Lewis, Stephanie J. Smith, Howard A. Zaren, Gayathri Nagaraj, Mojtaba Akhtari, Dan R. Castillo, Eric Lau, Mark E. Reeves, Stephanie Berg, Natalie Knox, Timothy E. O’Connor, Eric B. Durbin, Amit A. Kulkarni, Heather H. Nelson, Zohar Sachs, Rachel P. Rosovsky, Kerry L. Reynolds, Aditya Bardia, Genevieve Boland, Justin F. Gainor, Leyre Zubiri, Thorvardur R. Halfdanarson, Tanios S. Bekaii-Saab, Aakash Desai, Irbaz B. Riaz, Surbhi Shah, Katherine E. Smith, Colt Williams, Nathaniel Bouganim, Arielle Elkrief, Justin Panasci, Donald C. Vinh, Gregory J. Riely, Rimma Belenkaya, John Philip, Bryan Faller, Rana R. McKay, Archana Ajmera, Sharon S. Brouha, Sharon Choi, Albert Hsiao, Seth Kligerman, Taylor K. Nonato, Erin G. Reid Sibel Blau, Sachin R. Jhawar, Daniel Addison, James L. Chen, Margaret E. Gatti-Mays, Vidhya Karivedu, Vidhya Karivedu, Joshua D. Palmer, Daniel G. Stover, Sarah Wall, Nicole O. Williams, Monika Joshi, Hyma V. Polimera, Lauren D. Pomerantz, Marc A. Rovito, Elizabeth A. Griffiths, Pragati G. Advani, Igor Puzanov, Salma K. Jabbour, Christian F. Misdary, Mansi R. Shah, Gerald Batist, Erin Cook, Miriam Santos Dutra, Cristiano Ferrario, Wilson H. Miller Jr., Babar Bashir, Christopher McNair, Sana Z. Mahmood, Vasil Mico, Andrea Verghese Rivera, Natasha C. Edwin, Melissa Smits, Deborah B. Doroshow, Matthew D. Galsky, Michael Wotman, Alyson Fazio, Julie C. Fu, Kathryn E. Huber, Mark H. Sueyoshi, Vadim S. Koshkin, Hala T. Borno, Daniel H. Kwon, Eric J. Small, Sylvia Zhang, Samuel M. Rubinstein, William A. Wood, Tessa M. Andermann, Christopher Jensen, Daniel W. Bowles, Christoper L. Geiger, Lawrence E. Feldman, Kent F. Hoskins, Gerald Gantt Jr., Li C. Liu, Mahir Khan, Ryan H. Nguyen, Mary Pasquinelli, Candice Schwartz, Neeta K. Venepalli, Blanche H. Mavromatis, Ragneel R. Bijjula, Qamar U. Zaman, David M. Aboulafiam, Brett A. Schroeder, Umit Topaloglu, Saif I. Alimohamed, Joan K. Moore, Prakash Peddi, Lane R. Rosen, Briana Barrow McCollough, Navid Hafez, Roy Herbst, Patricia LoRusso, Maryam B. Lustberg, Tyler Masters, Catherine Stratton

CA916798 predicts poor prognosis and promotes Gefitinib resistance for lung adenocarcinoma

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Jian He, Xi Lan, Xiayan Liu, Caixia Deng, Hu Luo, Yan Wang, Ping Kang, Zhijian Sun, Lintao Zhao, Xiangdong Zhou

Exposure to nonanoic acid alters small intestinal neuroendocrine tumor phenotype

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Bilal Almobarak, Vishal Amlani, Linda Inge, Tobias Hofving, Andreas Muth, Ola Nilsson, Martin Johansson, Yvonne Arvidsson, Erik Elias

Tolerability of concurrent external beam radiotherapy and [177Lu]Lu-PSMA-617 for node-positive prostate cancer in treatment naïve patients, phase I study (PROQURE-I trial)

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Esmée C. A. van der Sar, Arthur J. A. T. Braat, Jochem R. N. van der Voort- van Zyp, Betty S. van der Veen, Pim J. van Leeuwen, Daphne M. V. de Vries-Huizing, Jeroen M. A. Hendrikx, Marnix G. E. H. Lam, Wouter V. Vogel

Negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cells and patient prognosis after breast cancer surgery

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Fang Xin Jian, Peng Xiao Bao, Wang Fu Li, Yan Hai Cui, Hang Guan Hong

Efficacy and safety analysis of TACE + sunitinib vs. sunitinib in the treatment of unresectable advanced renal cell carcinoma: a retrospective study

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Haohao Lu, Qing Ye, Chuansheng Zheng, Li Fan, Xiangwen Xia

Protocol for the SEHNeCa randomised clinical trial assesing Supervised Exercise for Head and Neck Cancer patients

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M. Rodriguez-Arietaleanizbeaskoa, E Mojas Ereño, MS Arietaleanizbeaskoa, G. Grandes, A Rodríguez Sánchez, V. Urquijo, I Hernando Alday, M. Dublang, G. Angulo-Garay, J. Cacicedo, Mario Rodriguez-Arietaleanizbeaskoa, Egoitz Mojas Ereño, Maria S. Arietaleanizbeaskoa, Gonzalo Grandes, Arturo Garcia-Alvarez, Aitor Coca, Nere Mendizabal, Olga del Hoyo, Javier García-Escobedo, Ángel Rodríguez Sánchez, Lucía Flores Barrenechea, Rebeca Sánchez, Virginia Urquijo, Luis Barbier Herrero, Goiztidi Díaz-Basterra, Javier Gómez-Suarez, Laura A Calles Romero, Natalia C. Iglesias-Hernandez, Iñigo Hernando Alday, Maddalen Dublang, Lina M. Ramirez-Garcia, Garazi Angulo-Garay, Silvia Dominguez-Martinez, Erreka Gil-Rey, Aitor Martinez-Aguirre, Borja Gutierrez-Santamaria, Jon Cacicedo

Bibliometric analysis of Ewing sarcoma from 1993 to 2022

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Guangtao Han, Ting Liu, Pengde Kang

SAFESTEREO: phase II randomized trial to compare stereotactic radiosurgery with fractionated stereotactic radiosurgery for brain metastases

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J. A. Crouzen, A. L. Petoukhova, M. L. D. Broekman, M. Fiocco, U. J. Fisscher, J. H. Franssen, C. G. M. Gadellaa-van Hooijdonk, M. Kerkhof, M. Kiderlen, M. E. Mast, C. M. van Rij, R. Nandoe Tewarie, M. A. E. van de Sande, P. P. G. van der Toorn, R. Vlasman, M. J. Vos, N. C. M. G. van der Voort van Zyp, R. G. J. Wiggenraad, L. M. Wiltink, J. D. Zindler

Characterization of renal artery variation in patients with clear cell renal cell carcinoma and the predictive value of accessory renal artery in pathological grading of renal cell carcinoma: a retrospective and observational study

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Dingyang Lv, Huiyu Zhou, Fan Cui, Jie Wen, Weibing Shuang

The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma

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Song Tong, Ni Jiang, Jun-Hao Wan, Chong-Rui Chen, Si-Hua Wang, Chuang-Yan Wu, Qiang Guo, Xiao-Yue Xiao, Huan Huang, Ting Zhou

Increased incidence and improved survival in endometrial cancer in Sweden 1960–2014: a population-based registry survey

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Filip Herbst, Paul W. Dickman, Louise Moberg, Thomas Högberg, Christer Borgfeldt

A serum protein signature at the time of Uveal Melanoma diagnosis predicts long-term patient survival

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Christina Herrspiegel, Flavia Plastino, Emma Lardner, Stefan Seregard, Pete A. Williams, Helder André, Gustav Stålhammar

Oncological healthcare providers’ perspectives on appropriate melanoma survivorship care: a qualitative focus group study

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Nadia C. W. Kamminga, Marlies Wakkee, Rianne J. De Bruin, Astrid. A. M. van der Veldt, Arjen Joosse, Suzan W. I. Reeder, Peter W. Plaisier, Tamar Nijsten, Marjolein Lugtenberg

Abdominal fat and muscle distributions in different stages of colorectal cancer

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Jun Han, Xinyang Liu, Min Tang, Fan Yang, Zuoyou Ding, Guohao Wu

NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling

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Shuaijun Ma, Yafan Chen, Penghe Quan, Jingliang Zhang, Shichao Han, Guohui Wang, Ruochen Qi, Xiaoyan Zhang, Fuli Wang, Jianlin Yuan, Xiaojian Yang, Weijing Jia, Weijun Qin

Residual fibroglandular breast tissue after mastectomy is associated with an increased risk of a local recurrence or a new primary breast cancer"

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Christine Deutschmann, Christian F. Singer, Daphne Gschwantler-Kaulich, Georg Pfeiler, Carmen Leser, Pascal A. T. Baltzer, Thomas H. Helbich, Christine Kraus, Ricarda Korbatits, Alaa Marzogi, Paola Clauser

Comparative efficacy of different combinations of acapella, active cycle of breathing technique, and external diaphragmatic pacing in perioperative patients with lung cancer: a randomised controlled trial

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Xiaoxue Chen, Chuanzhen Li, Linjuan Zeng, Tiehua Rong, Peng Lin, Qinglin Wang, Zhixing Guo, Hao Long, Jiudi Zhong

Real-world management and outcomes of older patients with locally advanced esophageal squamous cell carcinoma: a multicenter retrospective study

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Yuki Saito, Yasuo Hamamoto, Kenro Hirata, Makoto Yamasaki, Masaya Watanabe, Tetsuya Abe, Yasuhiro Tsubosa, Yoichi Hamai, Kentaro Murakami, Takeo Bamba, Takako Yoshii, Masahiro Tsuda, Masayuki Watanabe, Masaki Ueno, Yuko Kitagawa

Machine learning integrations develop an antigen-presenting-cells and T-Cells-Infiltration derived LncRNA signature for improving clinical outcomes in hepatocellular carcinoma

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Xiaodong Wang, Ji Chen, Lifan Lin, Yifei Li, Qiqi Tao, Zhichao Lang, Jianjian Zheng, Zhengping Yu

ORC6, a novel prognostic biomarker, correlates with T regulatory cell infiltration in prostate adenocarcinoma: a pan-cancer analysis

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Yuan Lin, Ying Zhang, Zhouting Tuo, Liang Gao, Demao Ding, Liangkuan Bi, Dexin Yu, Zhengmei Lv, Jiani Wang, Xin Chen

Association of novel and conventional obesity indices with colorectal cancer risk in older Chinese: a 14-year follow-up of the Guangzhou Biobank Cohort Study

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Shu Yi Wang, Wei Sen Zhang, Chao Qiang Jiang, Ya Li Jin, Tong Zhu, Feng Zhu, Lin Xu

Peripheral PD-1 and Tim-3 percentages are associated with primary sites and pathological types of peritoneal neoplasms

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Huihui Hu, Jin Zhao, Judong Yuan, Man Zhang

RRM2 and CDC6 are novel effectors of XBP1-mediated endocrine resistance and predictive markers of tamoxifen sensitivity

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David Barua, Afrin Sultana, Md Nahidul Islam, Fergus Cox, Ananya Gupta, Sanjeev Gupta

Clinical efficacy and prognosis analysis of treatment regimens for EGFR mutant non-small cell lung cancer and brain metastasis: a retrospective study

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Huijuan Wang, Ruyue Xing, Mengmeng Li, Mina Zhang, Chunhua Wei, Guowei Zhang, Yuanyuan Niu, Zhiyong Ma, Xiangtao Yan

CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation

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Shiqi Lu, Tong Lu, Jiayu Zhang, Lunbiao Gan, Xinjie Wu, Donghui Han, Keying Zhang, Chao Xu, Shaojie Liu, Weijun Qin, Fa Yang, Weihong Wen

Quantification of mitochondrial cfDNA reveals new perspectives for early diagnosis of colorectal cancer

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Christian Linke, Richard Hunger, Mark Reinwald, Markus Deckert, René Mantke

Aspartate beta-hydroxylase domain containing 1 as a prognostic marker associated with immune infiltration in skin cutaneous melanoma

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Shiquan Sun, Min Deng, Juan Wen, Xiaoyuan Chen, Jiaqi Xu, Yu Liu, Huanhuan Wan, Jin Wang, Leping Yan, Yong He, Yunsheng Xu

Disparities in oesophageal cancer risk by age, sex, and nativity in Kuwait:1980–2019

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Saeed Akhtar, Ahmad Al-Shammari, Mohammad Al-Huraiti , Fouzan Al-Anjery, Salman Al-Sabah, Anjum Memon, Iqbal Siddique

Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers

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Jianjiang Xie, Weishen Yao, Lingxiu Chen, Wenjun Zhu, Qiang Liu, Geng Geng, Jing Fang, Yang Zhao, Li Xiao, Zhenhua Huang, Jing Zhao

Prognostic value of CYFRA 21 − 1 and Ki67 in advanced NSCLC patients with wild-type EGFR

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Tao Li, Qi Xie, Yang-Yang Fang, Yi Sun, Xiao Ming Wang, Zhu Luo, Gui-Ling Yan, Jian-Bo He, Xiao-Qun Zheng

Integrated pancancer analysis reveals the oncogene characteristics and prognostic value of DIP2B in breast cancer

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Chengyang Song, Fangjian Shang, Wei Tu, Xiaodan Liu

Responsiveness and construct validity of EPIC-26, AQoL-6D and SF-6D following treatment in prostate cancer

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Norma B. Bulamu, Christine Mpundu-Kaambwa, Michael O’Callaghan, Billingsley Kaambwa

High expression of TLR3 in triple-negative breast cancer predicts better prognosis—data from the Fudan University Shanghai Cancer Center cohort and tissue microarrays

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Lei Fan, Xin-Yi Sui, Xi Jin, Wen-Juan Zhang, Peng Zhou, Zhi-Ming Shao

Neoadjuvant chemotherapy induces an elevation of tumour apparent diffusion coefficient values in patients with ovarian cancer

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Milja Reijonen, Erikka Holopainen, Otso Arponen, Mervi Könönen, Ritva Vanninen, Maarit Anttila, Hanna Sallinen, Irina Rinta-Kiikka, Auni Lindgren

Associations of combined physical activity and body mass index groups with colorectal cancer survival outcomes

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Caroline Himbert, Jennifer Ose, Biljana Gigic, Richard Viskochil, Kelly Santuci, Tengda Lin, Anjelica Ashworth, Jessica N. Cohan, Courtney L. Scaife, Jolanta Jedrzkiewicz, Victoria Damerell, Katelyn M. Atkins, Jun Gong, Matthew G. Mutch, Corey Bernadt, Seth Felder, Julian Sanchez, Stacey A. Cohen, Mukta K. Krane, Nathan Hinkle, Elizabeth Wood, Anita R. Peoples, Jane C. Figueiredo, Adetunji T. Toriola, Erin M. Siegel, Christopher I. Li, David Shibata, Kenneth Boucher, June L. Round, Alexis B. Ulrich, Martin Schneider, Lyen C. Huang, Sheetal Hardikar, Cornelia M. Ulrich

Comprehensive analysis of ZNF family genes in prognosis, immunity, and treatment of esophageal cancer

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Kunqiao Hong, Qian Yang, Haisen Yin, Na Wei, Wei Wang, Baoping Yu

High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients

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Yasaman Rezaie, Fahimeh Fattahi, Baharnaz Mashinchi, Kambiz Kamyab Hesari, Sahar Montazeri, Elham Kalantari, Zahra Madjd, Leili Saeednejad Zanjani

Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis

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Wenting Tang, Qiong Shao, Zhanwen He, Xu Zhang, Xiaojuan Li, Ruohao Wu

Effectiveness of personalized treatment stage-adjusted digital therapeutics in colorectal cancer: a randomized controlled trial

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Inah Kim, Ji Young Lim, Sun Woo Kim, Dong Wook Shin, Hee Cheol Kim, Yoon Ah Park, Yoon Suk Lee, Jung-Myun Kwak, Seok Ho Kang, Ji Youl Lee, Ji Hye Hwang

Plasma hPG80 (Circulating Progastrin) as a Novel Prognostic Biomarker for early-stage breast cancer in a breast cancer cohort

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Alexandre Prieur, Andrew Harper, Momtafin Khan, Bérengère Vire, Dominique Joubert, Léa Payen, Karen Kopciuk

Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling

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Jian Gao, Jifen Hu, Fang Yu, Chunlin Wang, Danmei Sheng, Wuling Liu, Anling Hu, Kunling Yu, Xiao Xiao, Yi Kuang, Eldad Zacksenhaus, Babu Gajendran, Yaacov Ben-David

KIF2C is a prognostic biomarker associated with immune cell infiltration in breast cancer

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Shanshan Liu, Ziwei Ye, Vivian Weiwen Xue, Qi Sun, Huan Li, Desheng Lu

Does resection after neoadjuvant chemotherapy of docetaxel, oxaliplatin, and S-1 (DOS regimen) benefit for gastric cancer patients with single non-curable factor? a multicenter, prospective cohort study (Neo-REGATTA)

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Yuehong Cui, Yiyi Yu, Song Zheng, Jie’er Ying, Yi’an Du, Yan Wang, Xuefei Wang, Zhenbin Shen, Fenglin Liu, Minzhi Lv, Yihong Sun, Tianshu Liu

Activity and safety of KEES - an oral multi-drug chemo-hormonal metronomic combination regimen in metastatic castration-resistant prostate cancer

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Mustafa Asowed, Nils O Elander, Linn Pettersson, Maria Ekholm, Dimitrios Papantoniou

The potential of PARP as a therapeutic target across pediatric solid malignancies

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Kaylee M. Keller, Joost Koetsier, Linda Schild, Vicky Amo-Addae, Selma Eising, Kim van den Handel, Kimberley Ober, Bianca Koopmans, Anke Essing, Marlinde L. van den Boogaard, Karin P. S. Langenberg, Natalie Jäger, Marcel Kool, Stefan Pfister, M. Emmy M. Dolman, Jan J. Molenaar, Sander R. van Hooff

Prevalence, trends and distribution of lifestyle cancer risk factors in Uganda: a 20-year systematic review

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Annet Nakaganda, Immaculate Mbarusha, Angela Spencer, Lesley Patterson, Isla Gemmell, Andrew Jones, Arpana Verma

Incidence, survival comparison, and novel prognostic evaluation approaches for stage iii-iv pulmonary large cell neuroendocrine carcinoma and small cell lung cancer

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Liling Huang, Yu Feng, Tongji Xie, Haohua Zhu, Le Tang, Yuankai Shi

ATM depletion induces proteasomal degradation of FANCD2 and sensitizes neuroblastoma cells to PARP inhibitors

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Sultana Parvin, Jesmin Akter, Hisanori Takenobu, Yutaka Katai, Shunpei Satoh, Ryu Okada, Masayuki Haruta, Kyosuke Mukae, Tomoko Wada, Miki Ohira, Kiyohiro Ando, Takehiko Kamijo

Risk factors for cancer of unknown primary: a literature review

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Karlijn E. P. E. Hermans, Fatemeh Kazemzadeh, Caroline Loef, Rob L. H. Jansen, Iris D. Nagtegaal, Piet A. van den Brandt, Leo J. Schouten

Aberrant methylation in neurofunctional gene serves as a hallmark of tumorigenesis and progression in colorectal cancer

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Xuan Li, Du Cai, Yaoyi Huang, Yumo Xie, Dingcheng Shen, Ze Yuan, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Huichuan Yu, Xiaolin Wang

Clinical benefit of subsequent chemotherapy after drug-induced interstitial lung disease in pancreatic cancer patients: a multicenter retrospective study from Japan

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Hiroki Irie, Rei Suzuki, Yoshinori Okubo, Hiroyuki Asama, Naoki Konno, Yuki Noguchi, Ko Watanabe, Goro Shibukawa, Hidemichi Imamura, Tadayuki Takagi, Mitsuru Sugimoto, Yuki Sato, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Takumi Yanagita, Takuto Hikichi, Hiromasa Ohira

Time trends in survival and causes of death in multiple myeloma: a population-based study from Germany

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Christine Eisfeld, Hiltraud Kajüter, Lennart Möller, Ina Wellmann, Evgenii Shumilov, Andreas Stang

First-line atezolizumab/durvalumab plus platinum–etoposide combined with radiotherapy in extensive-stage small-cell lung cancer

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Lijuan Li, Dan Yang, Yanmei Min, Anyan Liao, Jing Zhao, Leilei Jiang, Xin Dong, Wei Deng, Huiming Yu, Rong Yu, Jun Zhao, Anhui Shi

Clinical and prognostic significance of perioperative change in red cell distribution width in patients with esophageal squamous cell carcinoma

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Peng Zhang, Sheng Wang, Jun-zhou Wu, Qian Song

Efficacy and safety of transurethral resection of bladder tumour combined with chemotherapy and immunotherapy in bladder-sparing therapy in patients with T1 high-grade or T2 bladder cancer: a protocol for a randomized controlled trial

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Xiangwei Yang, Shiqiang Zhang, Yajiao Cui, Yamei Li, Xinyue Song, Jun Pang

Whole-exome mutational landscape and molecular marker study in mucinous and clear cell ovarian cancer cell lines 3AO and ES2

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Jianxiong Li, Huaguo Liang, Wentao Xiao, Peng Wei, Hongmei Chen, Zexin Chen, Ruihui Yang, Huan Jiang, Yongli Zhang

Elemental profiles in distant tissues during tumor progression

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Samella Salles, Rebecca Salles, Mauro S. G. Pavão, Simone C. Cardoso, Mariana P. Stelling

Identification of hub genes and pathways in lung metastatic colorectal cancer

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Wei Dai, Caiyao Guo, Yu Wang, Yumei Li, Renjian Xie, Junhong Wu, Baole Yao, Dong Xie, Ling He, Yingying Li, Hao Huang, Yun Wang, Shenglan Liu

Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study

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Qiang Huang, Feiran Li, Mengyou Ji, Lan Lin, Chunyan Hu

Efficacy of adjuvant TACE on the prognosis of patients with HCC after hepatectomy: a multicenter propensity score matching from China

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Zhao Wu, Lifeng Cui, Junlin Qian, Laihui Luo, Shuju Tu, Fei Cheng, Lebin Yuan, WenJian Zhang, Wei Lin, Hongtao Tang, Xiaodong Li, Hui Li, Yang Zhang, Jisheng Zhu, Yong Li, Yuanpeng Xiong, Zemin Hu, Peng Peng, Yongzhu He, Liping Liu, Kun He, Wei Shen

Clinical markers of immunotherapy outcomes in advanced sarcoma

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Marium Husain, Dionisia Quiroga, Han Gil Kim, Scott Lenobel, Menglin Xu, Hans Iwenofu, James L. Chen, Claire Verschraegen, David Liebner, Gabriel Tinoco

A prospective cohort study on active surveillance after neoadjuvant chemoradiotherapy for esophageal cancer: protocol of Surgery As Needed for Oesophageal cancer-2

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Charlène J. van der Zijden, Sjoerd M. Lagarde, Merel Hermus, Leonieke W. Kranenburg, J. Jan B. van Lanschot, Bianca Mostert, Joost J. M. E. Nuyttens, Lindsey Oudijk, Pieter C. van der Sluis, Manon C. W. Spaander, Maria J. Valkema, Roelf Valkema, Bas P. L. Wijnhoven, Jan Willem T. Dekker, Willem E. Fiets, Hendrik H. Hartgrink, Wouter L. Hazen, Ewout A. Kouwenhoven, Grard A. P. Nieuwenhuijzen, Camiel Rosman, Johanna W. van Sandick, Meindert N. Sosef, Edwin S. van der Zaag

Pan-cancer analysis and experimental validation of DTL as a potential diagnosis, prognosis and immunotherapy biomarker

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Yumei Tang, Ye Lei, Peng Gao, Junting Jia, Huijun Du, Qitong Wang, Zhixin Yan, Chen Zhang, Guojun Liang, Yanfeng Wang, Weijun Ma, Nianzeng Xing, Le Cheng, Laifeng Ren

HOXA9 gene promotor methylation and copy number variation of SOX2 and HV2 genes in cell free DNA: A potential diagnostic panel for non-small cell lung cancer

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Abla Abou-Zeid, Doaa Hashad, Ayman Baess, Mai Mosaad, Eman Tayae

Association of progesterone receptor status with 21-gene recurrence score and survival among patients with estrogen receptor-positive breast cancer

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Sung Jun Ma, Jasmin Gill, Keerti Yendamuri, Udit Chatterjee, Olivia Waldman, Cynthia Dunne-Jaffe, Fatemeh Fekrmandi, Rohil Shekher, Austin Iovoli, Song Yao, Oluwadamilola T. Oladeru, Anurag K. Singh

Safety, efficacy and pharmacokinetics of BPI-9016M in c-MET overexpression or MET exon 14 skipping mutation patients with locally advanced or metastatic non-small-cell lung cancer: a phase Ib study

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Xingsheng Hu, Xinge Cui, Ziping Wang, Yunpeng Liu, Ying Luo, Wei Zhong, Hui Zhao, Mengxing Yao, Da Jiang, Mingxia Wang, Minjiang Chen, Xin Zheng, Lieming Ding, Yang Wang, Xiaobin Yuan, Pengxiang Wu, Bei Hu, Xiaohong Han, Yuankai Shi

Utility of AMACR immunohistochemical staining in differentiating Arias-Stella reaction from clear cell carcinoma of ovary and endometrium

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Fatemeh Nili, Masoumeh Sadri, Fereshteh Ameli

Intrathecal chemotherapy combined with systemic therapy in patients with refractory leptomeningeal metastasis of non-small cell lung cancer: a retrospective study

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Tao Zhou, Shaofeng Zhu, Qiang Xiong, Jiongli Gan, Jianping Wei, Jing Cai, Anwen Liu

Sex and gender differences in treatment intention, quality of life and performance status in the first 100 patients with periampullary cancer enrolled in the CHAMP study

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Sofie Olsson Hau, Caroline Williamsson, Bodil Andersson, Jakob Eberhard, Karin Jirström

SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway

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Kun Shang, Nina Ma, Juanjuan Che, Huihui Li, Jiexuan Hu, Haolin Sun, Bangwei Cao

Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer

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Jie Yu, Qi Sun, Yi Hui, Jinping Xu, Pancheng Shi, Yu Chen, Yunzhao Chen

Predictors and characteristics of Rib fracture following SBRT for lung tumors

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Michael P. Carducci, Baskaran Sundaram, Benjamin A. Greenberger, Maria Werner-Wasik, Gregory C. Kane

Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort

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Eva Grundmann, Alessandra Curioni-Fontecedro, Emanuel Christ, Alexander R. Siebenhüner

Increased prevalence of the founder BRCA1 c.5309G>T and recurrent BRCA2 c.1310_1313delAAGA mutations in breast cancer families from Northerstern region of Morocco: evidence of geographical specificity and high relevance for genetic counseling

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Rahma Melki, Marouane Melloul, Souria Aissaoui, Tijani EL Harroudi, Noureddine Boukhatem

Automated Breast Ultrasound (ABUS)-based radiomics nomogram: an individualized tool for predicting axillary lymph node tumor burden in patients with early breast cancer

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Yu Chen, Yongwei Xie, Bo Li, Hua Shao, Ziyue Na, Qiucheng Wang, Hui Jing

Cervical cancer survival prediction by machine learning algorithms: a systematic review

• Open Access
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Milad Rahimi, Atieh Akbari, Farkhondeh Asadi, Hassan Emami

Effects of preoperative albumin-to-globulin ratio on overall survival and quality of life in esophageal cell squamous carcinoma patients: a prospective cohort study

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Juwei Zhang, Zheng Lin, Jinsong Zhou, Yue Huang, Siting Chen, Yuan Deng, Minglian Qiu, Yuanmei Chen, Zhijian Hu

Eta polycaprolactone (ε-PCL) implants appear to cause a partial differentiation of breast cancer lung metastasis in a murine model

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Benjamin Benzon, Sandra Marijan, Matij Pervan, Vedrana Čikeš Čulić

Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol)

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• Study Protocol

Emilie Thivat, Mélanie Casile, Juliette Moreau, Ioana Molnar, Sandrine Dufort, Khalide Seddik, Géraldine Le Duc, Olivier De Beaumont, Markus Loeffler, Xavier Durando, Julian Biau

Real-life experiences with CAR T-cell therapy with idecabtagene vicleucel (ide-cel) for triple-class exposed relapsed/refractory multiple myeloma patients

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Dilara Akhoundova Sanoyan, Katja Seipel, Ulrike Bacher, Marie-Noelle Kronig, Naomi Porret, Gertrud Wiedemann, Michael Daskalakis, Thomas Pabst

The V protein in oncolytic Newcastle disease virus promotes HepG2 hepatoma cell proliferation at the single-cell level

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Zhili Chu, Sihui Yang, Qianru Li, Jianing Shang, Zilong Ren, Feng Ren

Carbohydrate quality indices and colorectal cancer risk: a case-control study

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Masoud Amini Kahrizsangi, Zohreh Ebrahimi, Zainab Shateri, Fatemeh Mansouri, Ali Zangene, Milad Rajabzadeh-Dehkordi, Mehran Nouri, Bahram Rashidkhani

“What I wanted to do was build myself back up and prepare”: qualitative findings from the PERCEPT trial of prehabilitation during autologous stem cell transplantation in myeloma

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Orla McCourt, Abigail Fisher, Joanne Land, Gita Ramdharry, Anna L Roberts, Georgios Bekris, Kwee Yong

The epidemiology of multiple primary cancers in Belgium (2004–2017): Incidence, proportion, risk, stage and impact on relative survival estimates

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Gilles Macq, Geert Silversmit, Freija Verdoodt, Liesbet Van Eycken

Symptom management care pathway adaptation process and specific adaptation decisions

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Emily Vettese, Farha Sherani, Allison A. King, Lolie Yu, Catherine Aftandilian, Christina Baggott, Vibhuti Agarwal, Ramamoorthy Nagasubramanian, Kara M. Kelly, David R. Freyer, Etan Orgel, Scott M. Bradfield, Wade Kyono, Michael Roth, Lisa M. Klesges, Melissa Beauchemin, Allison Grimes, George Tomlinson, L. Lee Dupuis, Lillian Sung

The Effect of immunonutrition in patients undergoing pancreaticoduodenectomy: a systematic review and meta-analysis

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Yinyin Fan, Nianxing Li, Jing Zhang, Qiaomei Fu, Yudong Qiu, Yan Chen

Overall survival in patients with advanced non-small cell lung cancer with KRAS G12C mutation with or without STK11 and/or KEAP1 mutations in a real-world setting

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Cristina Julian, Navdeep Pal, Anda Gershon, Marie Evangelista, Hans Purkey, Peter Lambert, Zhen Shi, Qing Zhang

Chidamide enhances cytotoxicity of doxorubicin by promoting autophagy and apoptosis in breast cancer

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Jieqing Li

Efficacy of curcumin for amelioration of radiotherapy-induced oral mucositis: a preliminary randomized controlled clinical trial

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Vahid Ramezani, Shiva Ghadirian, Masoud Shabani, Mohammad Ali Boroumand, Reza Daneshvar, Fatemeh Saghafi

Identification of immunotherapy-related lncRNA signature for predicting prognosis, immunotherapy responses and drug candidates in bladder cancer

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Pengyu Hui, Feng Ni, Liang Zheng, Lei Jia, Zhe Wang

Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels

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Takahiro Arasawa, Takaki Hiwasa, Akiko Kagaya, Tetsuro Maruyama, Masaya Uesato, Masayuki Kano, Sohei Kobayashi, Hirotaka Takizawa, Katsuro Iwase, Fumio Nomura, Kazuyuki Matsushita, Hisahiro Matsubara

Protocol of the OPTIMAL study: Optimization of polypharmacy in geriatric oncology - A randomized controlled trial

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• Study Protocol

Ben Schöttker, Li-Ju Chen, Reiner Caspari, Hermann Brenner

PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy

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Heli J. Sistonen, Taru Ilmarinen, Timo Atula, Katri Aro, Jukka Schildt, Antti Markkola

Correction: Novel fusion protein PK5-RL-Gal-3 C inhibits hepatocellular carcinoma via anti-angiogenesis and cytotoxicity

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• Correction

Xiaoge Gao, Pin Jiang, Xiaohuan Wei, Wei Zhang, Jiwei Zheng, Shishuo Sun, Hong Yao, Xiangye Liu, Qing Zhang

Improved uptake and survival with systemic treatments for metastatic non-small cell lung cancer: younger versus older adults

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Bonnie Leung, Aria Shokoohi, Zamzam Al-Hashami, Sara Moore, Alexandra Pender, Selina K. Wong, Ying Wang, Jonn Wu, Cheryl Ho

Risk factors for the development of severe breast cancer-related lymphedema: a retrospective cohort study

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Xiaozhen Liu, Kewang Sun, Hongjian Yang, Lingli Xia, Kefeng Lu, Xuli Meng, Yongfeng Li

The use of Lutetium-177 PSMA radioligand therapy with high dose rate brachytherapy for locally recurrent prostate cancer after previous definitive radiation therapy: a randomized, single-institution, phase I/II study (ROADSTER).

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• Study Protocol

Lucas C. Mendez, Aneesh Dhar, David Laidley, Madeleine Moussa, Jose A. Gomez, Joseph Chin, T-Y Lee, Jonathan D. Thiessen, Douglas Hoover, Kathleen Surrey, Joelle Helou, Vikram Velker, Rohann J. Correa, David D’Souza, Jane Bayani, Glenn Bauman

Highly sensitive droplet digital PCR for detection of RET fusion in papillary thyroid cancer

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Mengke Chen, Junyu Xue, Ye Sang, Wenting Jiang, Weiman He, Shubin Hong, Weiming Lv, Haipeng Xiao, Rengyun Liu

AC010883.5 promotes cell proliferation, invasion, migration, and epithelial-to-mesenchymal transition in cervical cancer by modulating the MAPK signaling pathway

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Qiyu Gan, Xia Huang, Wenrong Zhao, Hui Liu, Yan Xu, Xiaohua Zhang, Jingxin Cheng, Rui Chen

Develop and validate a radiomics space-time model to predict the pathological complete response in patients undergoing neoadjuvant treatment of rectal cancer: an artificial intelligence model study based on machine learning

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Jiaxuan Peng, Wei Wang, Hui Jin, Xue Qin, Jie Hou, Zhang Yang, Zhenyu Shu

Correction to: DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells

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• Correction

Weijing Li, Shuguang Liu, Chanjuan Wang, Lei Cui, Xiaoxi Zhao, Wei Liu, Ruidong Zhang, Zhigang Li

Tumor-infiltrating CD36+CD8+T cells determine exhausted tumor microenvironment and correlate with inferior response to chemotherapy in non-small cell lung cancer

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Yong-Qiang Ao, Jian Gao, Ling-Xian Zhang, Jie Deng, Shuai Wang, Miao Lin, Hai-Kun Wang, Jian-Yong Ding, Jia-Hao Jiang

Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays

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Nicola Bassi, Henrikke Nilsen Hovland, Kashif Rasheed, Elisabeth Jarhelle, Nikara Pedersen, Eunice Kabanyana Mchaina, Sara Marie Engelsvold Bakkan, Nina Iversen, Hildegunn Høberg-Vetti, Bjørn Ivar Haukanes, Per Morten Knappskog, Ingvild Aukrust, Elisabet Ognedal, Marijke Van Ghelue

An exploratory cross-sectional study of the effects of ongoing relationships with accompanying patients on cancer care experience, self-efficacy, and psychological distress

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Marie-Pascale Pomey, Monica Iliescu Nelea, Louise Normandin, Cécile Vialaron, Karine Bouchard, Marie-Andrée Côté, Maria Alejandra Rodriguez Duarte, Djahanchah Philip Ghadiri, Israël Fortin, Danielle Charpentier, Mélanie Lavoie-Tremblay, Nicolas Fernandez, Antoine Boivin, Michel Dorval, Mado Desforges, Catherine Régis, Isabelle Ganache, Lynda Bélanger, Zeev Rosberger, Michel Alain Danino, Jean-François Pelletier, Thi Trinh Thuc Vu, Michèle de Guise

Prognostic significance of lymphovascular invasion in patients with pT1b esophageal squamous cell carcinoma

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Linxiu Liu, Hua Lin, Guihua Shen, Yong Liu, Xiumin Qin, Yanling Yuan, Bingzhi Wang, Liyan Xue

Expression characteristics and their functional role of IGFBP gene family in pan-cancer

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Yingnan Liu, Shixuan Shen, Ziwei Yan, Lirong Yan, Hanxi Ding, Ang Wang, Qian Xu, Liping Sun, Yuan Yuan

Single-cell transcriptome analysis profiles the expression features of TMEM173 in BM cells of high-risk B-cell acute lymphoblastic leukemia

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Yiqing Cai, Xiaomin Chen, Tiange Lu, Zhuoya Yu, Shunfeng Hu, Jiarui Liu, Xiangxiang Zhou, Xin Wang

Meta-analysis of Osteopontin splice variants in cancer

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Yu An, Gulimirerouzi Fnu, Changchun Xie, Georg F. Weber

Altered expression of anti-apoptotic protein Api5 affects breast tumorigenesis

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Abhijith Kuttanamkuzhi, Debiprasad Panda, Radhika Malaviya, Gautami Gaidhani, Mayurika Lahiri

Aspirin or statin use in relation to survival after surgery for esophageal cancer: a population-based cohort study

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Dag Holmberg, Eivind Gottlieb-Vedi, Jakob Hedberg, Mats Lindblad, Fredrik Mattsson, Jesper Lagergren

SNRPD1 conveys prognostic value on breast cancer survival and is required for anthracycline sensitivity

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Xiaofeng Dai, Linhan Cai, Zhifa Zhang, Jitian Li

High leukocyte mitochondrial DNA copy number contributes to poor prognosis in breast cancer patients

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Wenzhe Zhang, Songping Lin, Bangwei Zeng, Xiaobin Chen, Lili Chen, Minyan Chen, Wenhui Guo, Yuxiang Lin, Liuwen Yu, Jialin Hou, Yan Li, Shengmei Li, Xuan Jin, Weifeng Cai, Kun Zhang, Qian Nie, Hanxi Chen, Jing Li, Peng He, Qindong Cai, Yibin Qiu, Chuan Wang, Fangmeng Fu

Chemotherapy and targeted therapy for advanced biliary tract cancers: an umbrella review

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Yaoqun Wang, Ningyuan Wen, Shaofeng Wang, Guilin Nie, Yuan Tian, Jiong Lu, Bei Li

A phase 2 study of stereotactic body radiation therapy for squamous cell carcinoma of the head and neck (SHINE): a single arm clinical trial protocol

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• Study protocol

Justin Lee, Nhu Tram Nguyen, James Wright, Ka-Kit David Yeung, Stephen Sagar, Do-Hoon Kim, Orest Ostapiak, Lilian Doerwald-Munoz, Timothy Whelan

Impact of pharmacogenomic DPYD variant guided dosing on toxicity in patients receiving fluoropyrimidines for gastrointestinal cancers in a high-volume tertiary centre

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David K. Lau, Caroline Fong, Faten Arouri, Lillian Cortez, Hannah Katifi, Reyes Gonzalez-Exposito, Muhammad Bilal Razzaq, Su Li, Aislinn Macklin-Doherty, Monica Arenas Hernandez, Michael Hubank, Charlotte Fribbens, David Watkins, Sheela Rao, Ian Chau, David Cunningham, Naureen Starling

99mTc-MAA accumulation within tumor in preoperative lung perfusion SPECT/CT associated with occult lymph node metastasis in patients with clinically N0 non-small cell lung cancer

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Vanessa Murad, Minseok Suh, Hongyoon Choi, Gi Jeong Cheon, Kwon Joong Na, Young Tae Kim

Correction: Characteristics and outcomes of patients with RET-fusion positive non-small lung cancer in real-world practice in the United States

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Lisa M. Hess, Yimei Han, Yajun Emily Zhu, Naleen Raj Bhandari, Anthony Sireci

Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer

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Marta Wagner, Maciej Sobczyński, Monika Jasek, Konrad Pawełczyk, Irena Porębska, Piotr Kuśnierczyk, Andrzej Wiśniewski

The impact of PIK3CA mutations and PTEN expression on the effect of neoadjuvant therapy for postmenopausal luminal breast cancer patients

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Shouko Hayama, Rikiya Nakamura, Takayuki Ishige, Takafumi Sangai, Masahiro Sakakibara, Hiroshi Fujimoto, Emi Ishigami, Takahito Masuda, Ayako Nakagawa, Ryotaro Teranaka, Satoshi Ota, Sakae Itoga, Naohito Yamamoto, Takeshi Nagashima, Masayuki Otsuka

Dose prediction of organs at risk in patients with cervical cancer receiving brachytherapy using needle insertion based on a neural network method

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Huai-wen Zhang, Xiao-ming Zhong, Zhen-hua Zhang, Hao-wen Pang

Retraction Note: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

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• Retraction Note

Xue Hou, Run Gong, Jianhua Zhan, Ting Zhou, Yuxiang Ma, Yuanyuan Zhao, Yaxiong Zhang, Gang Chen, Zhonghan Zhang, Shuxiang Ma, Xi Chen, Fangfang Gao, Shaodong Hong, Fan Luo, Wenfeng Fang, Yunpeng Yang, Yan Huang, Likun Chen, Haoxian Yang, Li Zhang

Esculetin releases maturation arrest and induces terminal differentiation in leukemic blast cells by altering the Wnt signaling axes

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Ankit Mathur, Aman Gangwar, Daman Saluja

Liquid-liquid phase separation throws novel insights into treatment strategies for skin cutaneous melanoma

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Jianlan Liu, Shengbin Pei, Pengpeng Zhang, Keyu Jiang, Binlin Luo, Zuoqiong Hou, Gang Yao, Jian Tang

Clinical significance of serum-derived exosomal PD-L1 expression in patients with advanced pancreatic cancer

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Se Jun Park, Ju Yeon Park, Kabsoo Shin, Tae Ho Hong, MyungAh Lee, Younghoon Kim, In-Ho Kim

Feasibility of implementing a supervised telehealth exercise intervention in frail survivors of hematopoietic cell transplantation: a pilot randomized trial

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Kyuwan Lee, Justin Shamunee, Lanie Lindenfeld, Elizabeth Ross, Lindsey Hageman, Mina S. Sedrak, F. Lennie Wong, Ryotaro Nakamura, Stephen J. Forman, Smita Bhatia, Saro H. Armenian

Colorectal cancer screening completion by patients due or overdue for screening after reminders: a retrospective study

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Abdillahi M. Ahmed, Michael W. Bacchus, Stacy G. Beal, Katherine N. Huber, Ji-Hyun Lee, Jing Zhao, Thomas J. George, Maryam Sattari

CAA-derived IL-6 induced M2 macrophage polarization by activating STAT3

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Chongru Zhao, Ning Zeng, Xiaomei Zhou, Yufang Tan, Yichen Wang, Jun Zhang, Yiping Wu, Qi Zhang

A non-inferiority randomized phase III trial of standard immunotherapy by checkpoint inhibitors vs. reduced dose intensity in responding patients with metastatic cancer: the MOIO protocol study

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• Study Protocol

Gwenaelle Gravis, Patricia Marino, Daniel Olive, Frederique Penault-LLorca, Jean-Pierre Delord, Clotilde Simon, Assia Lamrani-Ghaouti, Renaud Sabatier, Joseph Ciccolini, Jean-Marie Boher

Laparoscopic versus open surgery for perihilar cholangiocarcinoma: a multicenter propensity score analysis of short- term outcomes

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Min Wang, Tingting Qin, Hang Zhang, Jingdong Li, Xiaxing Deng, Yuhua Zhang, Wenxing Zhao, Ying Fan, Dewei Li, Xuemin Chen, Yechen Feng, Siwei Zhu, Zhongqiang Xing, Guangsheng Yu, Jian Xu, Junjie Xie, Changwei Dou, Hongqin Ma, Gangshan Liu, Yue Shao, Weibo Chen, Jun Liu, Jianhua Liu, Xinmin Yin, Renyi Qin

Urinary tract infection after radiation therapy or radical prostatectomy on the prognosis of patients with prostate cancer: a population-based study

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Jihye Hyun, Moon Soo Ha, Seung Young Oh, Jong Hyun Tae, Byung Hoon Chi, In Ho Chang, Tae-Hyoung Kim, Soon Chul Myung, Tuan Thanh Nguyen, Jung Hoon Kim, Jin Wook Kim, Yong Seong Lee, Jooyoung Lee, Se Young Choi

Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

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Alaa Ibrahem Youssef, Gehad Mahmoud Khaled, Asma Amleh

Association between type of drinking water and upper gastrointestinal cancer incidence in the Linxian General Population

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Huan Yang, Jian-bing Wang, Xiao-kun Wang, Jin-hu Fan, You-lin Qiao

Radical prostatectomy versus external beam radiotherapy with androgen deprivation therapy for high-risk prostate cancer: a systematic review

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Berdine L. Heesterman, Katja K. H. Aben, Igle Jan de Jong, Floris J. Pos, Olga L. van der Hel

PTEN-negative endometrial cancer cells protect their genome through enhanced DDB2 expression associated with augmented nucleotide excision repair

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Fathima Hameed J S, Anjali Devarajan, Devu Priya M S, Ahel Bhattacharyya, Mayur Balkrishna Shirude, Debasree Dutta, Parimal Karmakar, Ananda Mukherjee

Neoadjuvant Chemoradiation for Rectal Cancer Achieves Satisfactory Tumour Regression and Local Recurrence – Result of a Dedicated Multi-disciplinary Approach from a South Asian Centre

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Raeed Deen, Dileepa S Ediriweera, Suchintha Thillakaratne, Janaki Hewavissenthi, Sumudu K Kumarage, Pramodh C. Chandrasinghe

Efficacy of aluminum chloride in severe regorafenib-associated hand-foot skin reactions: a single-arm trial

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Aya Nishizawa, Eiji Shinozaki, Takeru Wakatsuki, Takahiro Satoh, Naoya Yamazaki, Shunsuke Oyamada, Keisuke Ariyoshi, Kota Kihara, Masahiro Tsuboi, Kensei Yamaguchi

Tissue proteome analysis for profiling proteins associated with lymph node metastasis in gallbladder cancer

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Vaishali Jain, Javed Akhtar, Ratna Priya, Puja Sakhuja, Surbhi Goyal, Anil Kumar Agarwal, Vivek Ghose, Ravindra Varma Polisetty, Ravi Sirdeshmukh, Fouzia Siraj, Poonam Gautam

Elevated LILRB1 expression predicts poor prognosis and is associated with tumor immune infiltration in patients with glioma

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Renheng Zou, Xunlong Zhong, Kairong Liang, Cheng Zhi, Danmin Chen, Zhichao Xu, Jingbai Zhang, Degui Liao, Miaoling Lai, Yuhao Weng, Huaidong Peng, Xiao Pang, Yunxiang Ji, Yanbin Ke, Hongri Zhang, Zhaotao Wang, Yezhong Wang

Identification of SPRYD4 as a tumour suppressor predicts prognosis and correlates with immune infiltration in cholangiocarcinoma

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Zuyi Ma, Tiange Xie, Jia Sun, Jianchun Yu, Shanzhou Huang, Qi Zhou, Binglu Li

Risk of cervical intraepithelial neoplasia grade 2 or worse in women aged ≥ 69 referred to colposcopy due to an HPV-positive screening test

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Berit B. Booth, Mette Tranberg, Line W. Gustafson, Anne G. Christiansen, Helle Lapirtis, Lisa M. Krogh, Ina Marie D. Hjorth, Anne Hammer

Prognostic role of CD74, CD10 and Ki-67 immunohistochemical expression in patients with diffuse malignant peritoneal mesothelioma: a retrospective study

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Yufei Liang, Chunying Li, Yingying Liu, Liang Tian, Dongliang Yang

Association between sexual behaviour and head and neck cancer in the French West Indies: a case-control study based on an Afro-Caribbean population

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Aviane Auguste, Stanie Gaete, Léah Michineau, Cécile Herrmann-Storck, Clarisse Joachim, Suzy Duflo, Jacqueline Deloumeaux, Danièle Luce

Identifies KCTD5 as a novel cancer biomarker associated with programmed cell death and chemotherapy drug sensitivity

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Yuan-Xiang Shi, Jian-Hua Yan, Wen Liu, Jun Deng

Model-based assessment of combination therapies – ranking of radiosensitizing agents in oncology

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Marcus Baaz, Tim Cardilin, Floriane Lignet, Astrid Zimmermann, Samer El Bawab, Johan Gabrielsson, Mats Jirstrand

Tumor residue in patients with stage II–IVA nasopharyngeal carcinoma who received intensity-modulated radiation therapy: development and validation of a prediction nomogram integrating postradiotherapy plasma Epstein–Barr virus deoxyribonucleic acid, clinical stage, and radiotherapy dose

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Ying-Ying Huang, Jia-Yu Zhou, Ze-Jiang Zhan, Liang-Ru Ke, Wei-Xiong Xia, Xun Cao, Zhuo-Chen Cai, Ying Deng, Xi Chen, Lu-Lu Zhang, Hao-Yang Huang, Xiang Guo, Xing Lv

Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

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Xinyi Chen, Mu Yang, Lu Wang, Yuan Wang, Jingyao Tu, Xiao Zhou, Xianglin Yuan

Integrated analysis of circulating and tissue proteomes reveals that fibronectin 1 is a potential biomarker in papillary thyroid cancer

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Guochao Ye, Xiaomei Zhang, Mansheng Li, Zixiang Lin, Yongcan Xu, Haoru Dong, Jie Zhou, Jiaqi Zhang, Sheng Wang, Yunping Zhu, Xiaobo Yu, Xu Qian

A real-world study of Afatinib plus ramucirumab in treatment-naïve, EGFR-mutated, non–small cell lung cancer

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Chun-Yao Huang, Hui-Li Huang, Chou-Chin Lan, Yi-Chih Huang, Yao-Kuang Wu

Circulating microRNAs as diagnostic biomarkers for melanoma: a systematic review and meta-analysis

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Nan Wu, Hongyan Sun, Qian Sun, Fangqing Zhang, Lingli Ma, Yue Hu, Xianling Cong

Proteogenomic characterization of ferroptosis regulators reveals therapeutic potential in glioblastoma

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Xinzhuang Wang, Hong Zhang, Mingchu Zhang, Xuezhi Zhang, Wenbin Mao, Ming Gao

Radiographic and α-fetoprotein response predict pathologic complete response to immunotherapy plus a TKI in hepatocellular carcinoma: a multicenter study

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Cheng Huang, Xiao-Dong Zhu, Ying-Hao Shen, Bin Xu, Dong Wu, Yuan Ji, Ling-Li Chen, Tian-Qiang Song, Wei Zhang, Zhi-Ming Zeng, Hua-Sheng Huang, Kui Wang, Lan-Qing Huang, Yong-Jun Chen, Yu-Chen Yang, Le-Du Zhou, Guo Long, Hai-Tao Zhao, Yun-Chao Wang, Ning-Ling Ge, Yi Chen, Chang-Jun Tan, Jian Zhou, Jia Fan, Hui-Chuan Sun

High expression of PPFIA1 in human esophageal squamous cell carcinoma correlates with tumor metastasis and poor prognosis

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Yongyin Gao, Lizhao Guan, Ran Jia, Wanyi Xiao, Youming Han, Yue Li, Peng Tang, Zhentao Yu, Hongdian Zhang

Biliary drainage combined with simultaneous 125I seed strand brachytherapy for the treatment of hilar cholangiocarcinoma

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Chengzhi Zhang, Mengyao Song, Zhanguo Sun, Yi Fang, Yiming Liu, Kaihao Xu, Xinwei Han, Dechao Jiao

Prediction of pathologic complete response after single-dose MR-guided partial breast irradiation in low-risk breast cancer patients: the ABLATIVE-2 trial—a study protocol

• Open Access
• Study Protocol

Yasmin A. Civil, Arlene L. Oei, Katya M. Duvivier, Nina Bijker, Philip Meijnen, Lorraine Donkers, Sonja Verheijen, Zdenko van Kesteren, Miguel A. Palacios, Laura J. Schijf, Ellis Barbé, Inge R. H. M. Konings, C. Willemien Menke -van der Houven van Oordt, Paulien G. Westhoff, Hanneke J. M. Meijer, Gwen M. P. Diepenhorst, Victor Thijssen, Florent Mouliere, Berend J. Slotman, Susanne van der Velde, H. J. G. Desirée van den Bongard

ZDHHC15 promotes glioma malignancy and acts as a novel prognostic biomarker for patients with glioma

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Zhen-Yuan Liu, Tian Lan, Feng Tang, Yong-Ze He, Jin-Sheng Liu, Jin-Zhou Yang, Xi Chen, Ze-Fen Wang, Zhi-Qiang Li

Treatment of FIGO 2018 stage IIIC cervical cancer with different local tumor factors

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Yanna Ye, Zhiqiang Li, Shan Kang, Yongxiu Yang, Bin Ling, Li Wang, Jilong Yao, Pengfei Li, Xueqin Wang, Shipeng Gong, Huijian Fan, Yanxiang Kong, Yuye Cao, Jinghe Lang, Ping Liu, Chunlin Chen

The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer

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Yuchong Yang, Yao Lu, Hui Tan, Ming Bai, Xia Wang, Shaohua Ge, Tao Ning, Le Zhang, Jingjing Duan, Yansha Sun, Rui Liu, Hongli Li, Yi Ba, Ting Deng

JMJD2A participates in cytoskeletal remodeling to regulate castration-resistant prostate cancer docetaxel resistance

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Xiang Cai, Xi Duan, Tielong Tang, Shu Cui, Tao Wu

MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer

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Taiji Hamada, Michiyo Higashi, Seiya Yokoyama, Toshiaki Akahane, Masanori Hisaoka, Hirotsugu Noguchi, Tatsuhiko Furukawa, Akihide Tanimoto

Association between use of antihypertensive drugs and the risk of cancer: a population-based cohort study in Shanghai

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Suna Wang, Li Xie, Jianlin Zhuang, Ying Qian, Guanglu Zhang, Xiaowei Quan, Lei Li, Herbert Yu, Weituo Zhang, Wensui Zhao, Biyun Qian

Caprylic Acid (FFA C8:0) promotes the progression of prostate cancer by up-regulating G protein-coupled receptor 84/ Krüppel-like factor 7

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• Research article

Xue Li, Chenggang Yuan, Bingqi Yang, Huai Pang, Wei Li, Menghuan Li, Yihan Tang, Dingling Ma, Jianxin Xie, Jingzhou Wang, Jun Zhang

Behavioral activation for depression in patients with advanced cancer: study protocol for a multicenter randomized controlled trial

• Open Access
• Study Protocol

Takatoshi Hirayama, Yuko Ogawa, Asao Ogawa, Emi Igarashi, Saaya Soejima, Kotone Hata, Yusuke Utsumi, Yuki Mashiko, Kyoka Ogata, Ayako Kayano, Yuko Yanai, Shin-ichi Suzuki

Mediators and moderators of the effect of the game changers for cervical cancer prevention intervention on cervical cancer screening among previously unscreened social network members in Uganda

• Open Access
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Joseph KB Matovu, Glenn J. Wagner, Margrethe Juncker, Eve Namisango, Kathryn Bouskill, Sylvia Nakami, Jolly Beyeza-Kashesya, Emmanuel Luyirika, Rhoda K. Wanyenze

A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer

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Chuanzhong Huang, Ling Wang, Huijing Chen, Wankai Fu, Lingdong Shao, Dongmei Zhou, Junxin Wu, Yunbin Ye

Genome instability-related LINC02577, LINC01133 and AC107464.2 are lncRNA prognostic markers correlated with immune microenvironment in pancreatic adenocarcinoma

• Open Access
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Yinjiang Zhang, Yao Wang, Xu He, Rongfei Yao, Lu Fan, Linyi Zhao, Binan Lu, Zongran Pang

Development and validation of a radiopathomic model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer patients

• Open Access
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Jieqiu Zhang, Qi Wu, Wei Yin, Lu Yang, Bo Xiao, Jianmei Wang, Xiaopeng Yao

Prognostic value of preoperative hematological markers in patients with glioblastoma multiforme and construction of random survival forest model

• Open Access
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Xiaozong Duan, Bo Yang, Chengbin Zhao, Boran Tie, Lei Cao, Yuyuan Gao

Serum fatty acid profiles in breast cancer patients following treatment

• Open Access
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Alicja Pakiet, Agata Jędrzejewska, Katarzyna Duzowska, Alina Wacławska, Patrycja Jabłońska, Jacek Zieliński, Adriana Mika, Tomasz Śledziński, Ewa Słomińska

Tumor–stroma ratio predicts prognosis and PD-L1 expression in hepatocellular carcinoma

• Open Access
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Dong Wang, Jia Luo, YiMing Tao

Biological evaluation of novel gemcitabine analog in patient-derived xenograft models of pancreatic cancer

• Open Access
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Andriana Inkoom, Nkafu Bechem Ndemazie, Taylor Smith, Esther Frimpong, Raviteja Bulusu, Rosemary Poku, Xue Zhu, Bo Han, Jose Trevino, Edward Agyare

Hepatic passaging of NRAS-mutant melanoma influences adhesive properties and metastatic pattern

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Bianca Dietsch, Céline Weller, Carsten Sticht, Carolina de la Torre, Martin Kramer, Sergij Goerdt, Cyrill Géraud, Sebastian A. Wohlfeil

Low plasma PD-L1 levels, early tumor onset and absence of peritoneal carcinomatosis improve prognosis of women with advanced high-grade serous ovarian cancer

• Open Access
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Daniele Fanale, Chiara Brando, Lidia Rita Corsini, Sofia Cutaia, Mariano Catello Di Donna, Ugo Randazzo, Clarissa Filorizzo, Chiara Lisanti, Luigi Magrin, Vittorio Gurrera, Raffaella Romano, Alessandra Dimino, Tancredi Didier Bazan Russo, Daniel Olive, Salvatore Vieni, Gianni Pantuso, Antonio Giordano, Vito Chiantera, Antonio Russo, Viviana Bazan, Juan Lucio Iovanna

An exploratory study for tuft cells in the breast and their relevance in triple-negative breast cancer: the possible relationship of SOX9

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Yosuke Yamada, Ronald Simon, Kosuke Iwane, Yuki Nakanishi, Yasuhide Takeuchi, Akihiko Yoshizawa, Masahiro Takada, Masakazu Toi, Hironori Haga, Alexander Marx, Guido Sauter

The impact of the COVID-19 pandemic restrictions on the health care utilization of cancer patients

• Open Access
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Nico Schneider, Bernhard Strauss, Jutta Hübner, Christian Keinki, Florian Brandt, Sabine Rubai, Uwe Altmann

ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer

• Open Access
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Litong Yao, Yuwei Li, Siyuan Li, Mozhi Wang, Hongyi Cao, Ling Xu, Yingying Xu

A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines

• Open Access
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Brihget Sicairos, Shorna Alam, Yuchun Du

Cost-effectiveness of first-line immunotherapy combinations with or without chemotherapy for advanced non–small cell lung cancer: a modelling approach

• Open Access
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Wen Hui, Ruomeng Song, Hongyu Tao, Zhixiang Gao, Min Zhu, Mingyue Zhang, Huazhang Wu, Daichen Gong, Xiyan Zhang, Yuanyi Cai

Clinical activity of pembrolizumab with or without chemotherapy in advanced pulmonary large-cell and large-cell neuroendocrine carcinomas: a multicenter retrospective cohort study

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Lianxi Song, Fei Zhou, Tian Xu, Liang Zeng, Qing Xia, Zhan Wang, Li Deng, Yizhi Li, Haoyue Qin, Huan Yan, Zhe Huang, Jinye Mi, Qinqin Xu, Nong Yang, Caicun Zhou, Yongchang Zhang

ACSL4 serves as a novel prognostic biomarker correlated with immune infiltration in Cholangiocarcinoma

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Shuochen Liu, Shilong Fan, Yirui Wang, Ruixiang Chen, Ziyi Wang, Yaodong Zhang, Wangjie Jiang, Yananlan Chen, Xiao Xu, Yue Yu, Changxian Li, Xiangcheng Li

Progressive resolution optimizer (PRO) predominates over photon optimizer (PO) in sparing of spinal cord for spine SABR VMAT plans

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Sangjun Son, So-Yeon Park

Treatment benefit of upfront autologous stem cell transplantation for newly diagnosed multiple myeloma: a systematic review and meta-analysis

• Open Access
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Chi-Maw Lin, Lih-Chyun Chang, Wen-Yi Shau, Chi-Ling Chen, Chi-Yuan Yao, Feng-Ming Tien

PD-L1 stimulation can promote proliferation and survival of leukemic cells by influencing glucose and fatty acid metabolism in acute myeloid leukemia

• Open Access
• Research article

Mojdeh Soltani, Mustafa Ghanadian, Behrooz Ghezelbash, Abolfazl Shokouhi, Andrey A. Zamyatnin Jr, Alexandr V. Bazhin, Mazdak Ganjalikhani-Hakemi

Post-progression treatment in cancer randomized trials: a cross-sectional study of trials leading to FDA approval and published trials between 2018 and 2020

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Timothée Olivier, Alyson Haslam, Vinay Prasad

A randomized trial to evaluate the effects of a supervised exercise program on insomnia in patients with non-metastatic breast cancer undergoing chemotherapy: design of the FATSOMCAN study

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Chloé Drozd, Elsa Curtit, Quentin Jacquinot, Charlène Marquine, Laura Mansi, Loïc Chaigneau, Erion Dobi, Julien Viot, Guillaume Meynard, Marie-Justine Paillard, Morgan Goujon, Pauline Roux, Dewi Vernerey, Valérie Gillet, Hubert Bourdin, Silvio Galli, Nathalie Meneveau, Fabienne Mougin

Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial

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Shinya Abe, Kazushige Kawai, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Hiroyuki Matsuzaki, Yuzo Nagai, Yuichiro Yoshioka, Takahide Shinagawa, Hirofumi Sonoda, Yoko Yamamoto, Koji Oba, Soichiro Ishihara

Development and validation of a selenium metabolism regulators associated prognostic model for hepatocellular carcinoma

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Huishan Sun, Junyu Long, Bangyou Zuo, Yiran Li, Yu Song, Minghang Yu, Ziyu Xun, Yanyu Wang, Xi Wang, Xinting Sang, Haitao Zhao

Perineural invasion affects prognosis of patients undergoing colorectal cancer surgery: a propensity score matching analysis

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Le Qin, Yixin Heng, Shenghe Deng, Junnan Gu, Fuwei Mao, Yifan Xue, Zhenxing Jiang, Jun Wang, Denglong Cheng, Ke Wu, Yinghao Cao, Kailin Cai

Experiences of patients on cancer treatment regarding decentralization of oncology services at a tertiary hospital in the Eastern Cape

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Lumkile Wilmot Jojo, Nonyaniso Trustina Nkutu

Comprehensive transcriptomic analyses identify KDM genes-related subtypes with different TME infiltrates in gastric cancer

• Open Access
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Haichao Zhang, Haoran Wang, Li Ye, Suyun Bao, Ruijia Zhang, Ji Che, Wenqin Luo, Cheng Yu, Wei Wang

LncRNA-PVT1 was identified as a key regulator for TMZ resistance and STAT-related pathway in glioma

• Open Access
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Yusheng Chen, Fengjin Ma, Zhe Zhang, Yang Guo, Hanwei Shen, Hang Chen

Biliary-enteric reconstruction in laparoscopic radical resection of hilar cholangiocarcinoma: a single-center retrospective cohort study

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Wenzheng Liu, Fei Xiong, Guanhua Wu, Qi Wang, Bing Wang, Yongjun Chen

Joint effect of human papillomavirus exposure, smoking and alcohol on risk of oral squamous cell carcinoma

• Open Access
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Zheng Yang, Peng Sun, Kristina R. Dahlstrom, Neil Gross, Guojun Li

Clinical benefit of pembrolizumab in treatment of first line non-small cell lung cancer: a systematic review and meta-analysis of clinical characteristics

• Open Access
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Wenjie Liu, Gengwei Huo, Peng Chen

Estrogen receptor beta expression in triple negative breast cancers is not associated with recurrence or survival

• Open Access
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Elena A. Takano, Melissa M. Younes, Katie Meehan, Lisa Spalding, Max Yan, Prue Allan, Stephen B. Fox, Andy Redfern, David Clouston, Graham G. Giles, Elizabeth L. Christie, Robin L. Anderson, Magnus Zethoven, Kelly-Anne Phillips, Kylie Gorringe, Kara L. Britt

Multi-vendor evaluation of artificial intelligence as an independent reader for double reading in breast cancer screening on 275,900 mammograms

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Nisha Sharma, Annie Y. Ng, Jonathan J. James, Galvin Khara, Éva Ambrózay, Christopher C. Austin, Gábor Forrai, Georgia Fox, Ben Glocker, Andreas Heindl, Edit Karpati, Tobias M. Rijken, Vignesh Venkataraman, Joseph E. Yearsley, Peter D. Kecskemethy

Correction: Shikonin inhibits cancer cell cycling by targeting Cdc25s

• Open Access
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Shoude Zhang, Qiang Gao, Wei Li, Luwei Zhu, Qianhan Shang, Shuo Feng, Junmei Jia, Qiangqiang Jia, Shuo Shen, Zhanhai Su

Correction: Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

• Open Access
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Alvan Amos, Ning Jiang, Dan Zong, Jiajia Gu, Jiawei Zhou, Li Yin, Xia He, Yong Xu, Lirong Wu

Apatinib plus etoposide in pretreated patients with advanced triple-negative breast cancer: a phase II trial

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Mengru Cao, Hailing Lu, Shi Yan, Hui Pang, Lichun Sun, Chunhong Li, Xuesong Chen, Wei Liu, Jing Hu, Jian Huang, Ying Xing, Ningzhi Zhang, Yingqi Chen, Ting He, Danni Zhao, Yuanyuan Sun, Lin Zhao, Xiaomeng Liu, Li Cai

CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer

• Open Access
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Danhua Xu, Xu Liu, Shouyu Ke, Yixian Guo, Chunchao Zhu, Hui Cao

Real-world practice of conversion surgery for unresectable hepatocellular carcinoma - a single center data of 26 consecutive patients

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Bo Zhang, Xuetao Shi, Kai Cui, Zhongchao Li, Lei Li, Zhaogang Liu, Chengsheng Zhang, Pengfei Sun, Jingtao Zhong, Zhicheng Sun, Zhibin Chang, Zhao Ma, Alex Gordon-Weeks, Mingming Li, Lei Zhao

Cancer incidence and mortality in Brunei Darussalam, 2011 to 2020

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Elvynna Leong, Sok King Ong, Khairil Azhar Si-Ramlee, Lin Naing

Effects of neoadjuvant radiochemotherapy for anorectal function in locally advanced rectal cancer patients: a study protocol for a prospective, observational, controlled, multicentre study

• Open Access
• Study Protocol

Jie Shi, Yi-Kan Cheng, Fang He, Jian Zheng, Yun-Long Wang, Xiang-Bo Wan, Hong-Cheng Lin, Xin-Juan Fan

Analysis of stromal PDGFR-β and α-SMA expression and their clinical relevance in brain metastases of breast cancer patients

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Md Rashedunnabi Akanda, Eun-Jung Ahn, Yeong Jin Kim, S M Abdus Salam, Myung-Giun Noh, Tae-Kyu Lee, Sung Sun Kim, Kyung-Hwa Lee, Kyung-Sub Moon

Delay in diagnosis and associated factors among children with cancer admitted at pediatric oncology ward, University of Gondar comprehensive specialized hospital, Ethiopia: a retrospective cross-sectional study

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Yimenu Gardie, Mulugeta Wassie, Seid Wodajo, Mastewal Giza, Mulugeta Ayalew, Yihenew Sewale, Zelalem Feleke, Melkamu Tilahun Dessie

Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC)

• Open Access
• Study protocol

Linde Kehmann, Marie-Luise Berres, Maria Gonzalez-Carmona, Dominik P. Modest, Raphael Mohr, Alexander Wree, Marino Venerito, Christian Strassburg, Verena Keitel, Christian Trautwein, Tom Luedde, Christoph Roderburg

Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation

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Xueyan Cao, Yang Yang, Wei Zhou, Yue Wang, Xue Wang, Xianxiu Ge, Fei Wang, Fangfang Zhou, Xueting Deng, Lin Miao

Cervical cancer screening utilization and its predictors among women in bench Sheko Zone, Southwest Ethiopia: using health belief model

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Alemayehu Sayih Belay, Wondwossen Niguse Asmare, Aychew Kassie

Fusobacterium nucleatum-derived small extracellular vesicles facilitate tumor growth and metastasis via TLR4 in breast cancer

• Open Access
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Guiqiu Li, Yan Sun, Yu Huang, Jie Lian, Shaoyuan Wu, Dixian Luo, Hui Gong

Efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic therapy for the unresectable hepatocellular carcinoma and the benefit for hepatitis B virus etiology subgroup: a systematic review and meta-analysis of randomized controlled trials

• Open Access
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Danxue Huang, Liyuan Ke, Hongxia Cui, Su Li

Circulating tumor cells (CTCs) and hTERT gene expression in CTCs for radiotherapy effect with lung cancer

• Open Access
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Ying Xu, Xue Ren, Tong Jiang, Shuang Lv, Kuanke Gao, Yunen Liu, Ying Yan

Outcome and prognostic factors of CBF pediatric AML patients with t(8;21) differ from patients with inv(16)

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Kun-yin Qiu, Xiong-yu Liao, Yang Li, Ke Huang, Hong-gui Xu, Jian-pei Fang, Dun-hua Zhou

CT radiomics features of meso-esophageal fat in predicting overall survival of patients with locally advanced esophageal squamous cell carcinoma treated by definitive chemoradiotherapy

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Shuo Yan, Fei-Ping Li, Lian Jian, Hai-Tao Zhu, Bo Zhao, Xiao-Ting Li, Yan-Jie Shi, Ying-Shi Sun

ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer

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Ryo Kanai, Takeshi Uehara, Takahiro Yoshizawa, Masato Kamakura, Tomoyuki Nakajima, Yasuhiro Kinugawa, Mai Iwaya, Shiho Asaka, Masato Kitazawa, Tadanobu Nagaya, Hiroyoshi Ota

CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth

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Yihua Lin, Yiling Zhao, Minggui Chen, Zishuo Li, Qiao Liu, Jian Chen, Yi Ding, Chunyong Ding, Ye Ding, Cuiling Qi, Lingyun Zheng, Jiangchao Li, Rongxin Zhang, Jia Zhou, Lijing Wang, Qian-Qian Zhang

ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway

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Hao Yang, Kerstin Huebner, Chuanpit Hampel, Katharina Erlenbach-Wuensch, Selva Babu Selvamani, Vikas Shukla, Carol I. Geppert, Arndt Hartmann, Vijayalakshmi Mahadevan, Regine Schneider-Stock

Clinical research of the value of high-risk CTV setting on intensity-modulated radiotherapy for stage IIB-IVA cervical cancer

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Yuqi Jiang, Jing Wang, Peng Jiang, Xiang Wang, Lei Zhang, Yongchun Zhang

Survival differences between patients with de novo and relapsed/progressed advanced non-small cell lung cancer without epidermal growth factor receptor mutations or anaplastic lymphoma kinase rearrangements

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Byeong-Chan Oh, Ae-Ryeo Cho, Jin Hyun Nam, So-Young Yang, Min Ji Kim, Sun-Hong Kwon, Eui-Kyung Lee

Optimal sequencing of the first- and second-line target therapies in metastatic renal cell carcinoma: based on nationally representative data analysis from the Korean National Health Insurance System

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Dong Hyuk Kang, Joo Yong Lee, Yunhee Lee, U-Syn Ha

Is metabolism the magic bullet for targeted cancer therapy?

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• Editorial

Marija Trajkovic-Arsic, Elavarasan Subramani

Developing a nomogram for preoperative prediction of cervical cancer lymph node metastasis by multiplex immunofluorescence

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Jiangchun Wu, Qinhao Guo, Jun Zhu, Yong Wu, Simin Wang, Siyuan Liang, Xingzhu Ju, Xiaohua Wu

Dynamic changes of phenotype and function of natural killer cells in peripheral blood before and after thermal ablation of hepatitis B associated hepatocellular carcinoma and their correlation with tumor recurrence

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Hai-Yan Wang, Xiong-Wei Cui, Yong-Hong Zhang, Yu Chen, Ning-Ning Lu, Li Bai, Zhong-Ping Duan

Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1

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Fumiya Ito, Katsuhiro Kato, Izumi Yanatori, Yuki Maeda, Toyoaki Murohara, Shinya Toyokuni

Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing

• Open Access
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Danh D. Truong, Salah-Eddine Lamhamedi-Cherradi, Robert W. Porter, Sandhya Krishnan, Jyothishmathi Swaminathan, Amber Gibson, Alexander J. Lazar, J. Andrew Livingston, Vidya Gopalakrishnan, Nancy Gordon, Najat C. Daw, Nicholas E. Navin, Richard Gorlick, Joseph A. Ludwig

Hsp90 is a potential risk factor for ovarian cancer prognosis: an evidence of a Chinese clinical center

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Cancan Duan, KuoKuo Li, Xiaohua Pan, Zhaolian Wei, Lan Xiao

Thrombopoietin receptor agonist antibody for treating chemotherapy-induced thrombocytopenia

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Jiwon Shin, Min-Jung Kim, Xingguo Quan, Ji Woong Kim, Sukmook Lee, SaeGwang Park, Jee-Yeong Jeong, Kyungmoo Yea

Lactate metabolism-related genes to predict the clinical outcome and molecular characteristics of endometrial cancer

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Rui Shi, Haojia Li, Sitian Wei, Zhicheng Yu, Jun Zhang, Qi Zhang, Ting Zhou, Yuwei Yao, Qian Zhang, Tangansu Zhang, Hongbo Wang

Correlation between overall survival and quality of life in colon cancer patients with chemotherapy

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Yasuko Murakawa, Kazunori Ootsuka, Jun Kusaka, Kou Miura

Treatment of supraglottic squamous cell carcinoma with advanced technologies: observational prospective evaluation of oncological outcomes, functional outcomes, quality of life and cost-effectiveness (SUPRA-QoL)

• Open Access
• Study Protocol

S. Hassid, B. Krug, S. Deheneffe, J-F. Daisne, G. Delahaut, G. Lawson, R. Crott, S. Van der Vorst

Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling

• Open Access
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Sydney A. Pascetta, Sarah M. Kirsh, Makenna Cameron, James Uniacke

Characterization of immune checkpoints expression and lymphocyte densities of iranian breast cancer patients; the co-expression status and clinicopathological associates

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Mohammadhossein Pournabee, Mahsa Keshavarz-Fathi, Pooyesh Esmaeili, Pouya Mahdavi Sharif, Fatemeh Nili, Behnaz Jahanbin

The potential of high-order features of routine blood test in predicting the prognosis of non-small cell lung cancer

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Liping Luo, Yubo Tan, Shixuan Zhao, Man Yang, Yurou Che, Kezhen Li, Jieke Liu, Huaichao Luo, Wenjun Jiang, Yongjie Li, Weidong Wang

The impact and outcomes of cancer-macrophage fusion

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Mengtao Li, John R. Basile, Sanjay Mallya, Yi-Ling Lin

How frail is frail in oncology studies? A scoping review

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James A. Fletcher, Benignus Logan, Natasha Reid, Emily H. Gordon, Rahul Ladwa, Ruth E. Hubbard

A cisplatin conjugate with tumor cell specificity exhibits antitumor effects in renal cancer models

• Open Access
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Stefan Mrdenovic, Yanping Wang, Lijuan Yin, Gina Chia-Yi Chu, Yan Ou, Michael S. Lewis, Marija Heffer, Edwin M. Posadas, Haiyen E. Zhau, Leland W. K. Chung, Mouad Edderkaoui, Stephen J. Pandol, Ruoxiang Wang, Yi Zhang

A qualitative study examining newly diagnosed breast cancer patients’ experiences of participating in the Alberta Moving Beyond Breast Cancer (AMBER) prospective cohort study

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Lynn Corcoran, Christine M. Friedenreich, Margaret L. McNeely, Nicole S. Culos-Reed, Gordon Bell, Leanne Dickau, Kerry S. Courneya, Jeff K. Vallance

High HSPB1 expression predicts poor clinical outcomes and correlates with breast cancer metastasis

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Qin Huo, Juan Wang, Ni Xie

ABPEPserver: a web application for documentation and analysis of substitutants

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• Database

Abhijeet Pataskar, Jasmine Montenegro Navarro, Reuven Agami

Oral cavity and oropharyngeal carcinoma disparities in age and survival in Indigenous and non-Indigenous populations of Queensland

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Abdulrahman Sakeen Alkandari, Jemmi Ching Ying Ho, Siu Wai Choi, Peter Thomson

Optimizing identification of consensus molecular subtypes in muscle-invasive bladder cancer: a comparison of two sequencing methods and gene sets using FFPE specimens

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Florestan J. Koll, Claudia Döring, Csilla Olah, Tibor Szarvas, Jens Köllermann, Benedikt Hoeh, Felix K.-H. Chun, Henning Reis, Peter J. Wild

The pretherapeutic systemic inflammation score is a prognostic predictor for elderly patients with oesophageal cancer: a case control study

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Chunyue Huang, Mengyao Wang, Liwen Chen, Hongmei Wang, Donglan Huang, Jianjun Shi, Weijun Zhang, Yunhong Tian, Yujia Zhu

Incidence, survival, and associated factors estimation in osteosarcoma patients with lung metastasis: a single-center experience of 11 years in Tianjin, China

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Chao Zhang, Haixiao Wu, Guijun Xu, Yao Xu, Wenjuan Ma, Zhijun Li, Jin Zhang

FAP, CD10, and GPR77-labeled CAFs cause neoadjuvant chemotherapy resistance by inducing EMT and CSC in gastric cancer

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Zehua Zhao, Yanmei Zhu

Benefit finding in men affected by prostate cancer prior to and following radical prostatectomy – a cross-sectional study with a stratified sample

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Matthias Jahnen, Patrick Bayer, Valentin H. Meissner, Stefan Schiele, Helga Schulwitz, Jürgen E. Gschwend, Kathleen Herkommer, Andreas Dinkel

Prognostic role of E2F1 gene expression in human cancer: a meta-analysis

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Jingjing Li, Wen Bi, Fang Lu, Bei Pan, Mengqiu Xiong, Lubanga Nasifu, Zhenlin Nie, Bangshun He

Prognostic factors, oncological treatment and outcomes of uterine sarcoma: 10 years’ clinical experience from a tertiary care center in Pakistan

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Saqib Raza Khan, Salman Muhammad Soomar, Tamana Asghari, Arsalan Ahmed, Munira Shabbir Moosajee

MicroRNA-188-5p inhibits hepatocellular carcinoma proliferation and migration by targeting forkhead box N2

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Yan-hui Wu, Bin Yu, Jiang-min Zhou, Xue-han Shen, Wei-xun Chen, Xi Ai, Chao Leng, Bin-yong Liang, Ya-jie Shao

Interaction of lncRNAs with mTOR in colorectal cancer: a systematic review

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Marziyeh Sadat Moslehian, Roya Shabkhizan, Mohammad Reza Asadi, Ahad Bazmani, Mahdi Mahdipour, Sanya Haiaty, Reza Rahbarghazi, Ebrahim Sakhinia

S100A8, S100A9 and S100A8/A9 heterodimer as novel cachexigenic factors for pancreatic cancer-induced cachexia

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Wei-Chih Liao, Chih-Ta Chen, You-Shu Tsai, Xin-Ya Wang, Yen-Tzu Chang, Ming-Shiang Wu, Lu-Ping Chow

MMR gene patterns evaluation provides novel insights for personalized immunotherapy compared to neoadjuvant chemotherapy in lung adenocarcinama

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Liangliang Cai, Hujia Hua, Xingyu Jiang, Xintian Xu, Hua Bai, Li Qian, Jianchun Duan

Ninety-degree angled collimator: a dosimetric study related to dynamic intensity-modulated radiotherapy in patients with endometrial carcinoma

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Alparslan Serarslan, Yalçın Daştan, Telat Aksu, Rana Elif Yıldız, Bilge Gürsel, Deniz Meydan, Nilgün Özbek Okumuş

AQP8 promotes glioma proliferation and growth, possibly through the ROS/PTEN/AKT signaling pathway

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Zhang Hao, Sheng Huajun, Guo Zhen, Xing Yu, Liu Qian, Cai Ziling, Shen Zihao, Xia Qingqian, Zhu Shujuan

Clinical outcomes of intraluminal Iodine-125 seed strand brachytherapy and percutaneous nephrostomy in patients with ureteral carcinoma

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Yonghua Bi, Dechao Jiao, Jianhao Zhang, Yang Wang, Mengdan Su, Jianzhuang Ren, Xinwei Han

Size and number of lymph nodes were risk factors of recurrence in stage II colorectal cancer

• Open Access
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Shanyou Tong, Menglei Li, Yichao Bao, Long Zhang, Ping Lu, Tong Tong, Junjie Peng

Interleukin-24-mediated antitumor effects against human glioblastoma via upregulation of P38 MAPK and endogenous TRAIL-induced apoptosis and LC3-II activation-dependent autophagy

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Seyedeh Maliheh Babazadeh, Mohammad Reza Zolfaghari, Mohsen Zargar, Kazem Baesi, Sayed Younes Hosseini, Amir Ghaemi

The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study

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Ying E., Qian Yu, Tao Sun, Hang Xue, Xue-rong Zhao, Hua-chuan Zheng

EBV antibody and gastric cancer risk: a population-based nested case-control study in southern China

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Yun Du, Xia Yu, Ellen T. Chang, Li Yin, Shifeng Lian, Biaohua Wu, Fugui Li, Zhiheng Liang, Yumei Zeng, Bing Chu, Kuangrong Wei, Jiyun Zhan, Xuejun Liang, Weimin Ye, Mingfang Ji

Analyzing molecular typing and clinical application of immunogenic cell death-related genes in hepatocellular carcinoma

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Cai-Feng Lin, Zhi-Wen Chen, Feng-Ping Kang, Jian-Fei Hu, Long Huang, Cheng-Yu Liao, Jian-Lin Lai, Yi Huang, Zu-Wei Wang, Yi-Feng Tian, Shi Chen

Log odds of positive lymph nodes as a novel prognostic predictor for gastric cancer: a systematic review and meta-analysis

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Yiding Li, Guiling Wu, Jinqiang Liu, Yujie Zhang, Wanli Yang, Xiaoqian Wang, Lili Duan, Liaoran Niu, Junfeng Chen, Wei Zhou, Weili Han, Jing Wang, Helun Zhong, Gang Ji, Daiming Fan, Liu Hong

Transcriptomic and functional analysis of ANGPTL4 overexpression in pancreatic cancer nominates targets that reverse chemoresistance

• Open Access
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Emily R. Gordon, Carter A. Wright, Mikayla James, Sara J. Cooper

Characterization of stemness features and construction of a stemness subtype classifier to predict survival and treatment responses in lung squamous cell carcinoma

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Jinzhi Lai, Xinyi Lin, Huangna Zheng, Bilan Xie, Deqiang Fu

Expression and regulatory network of E3 ubiquitin ligase NEDD4 family in cancers

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Liangzi Cao, Hao Li, Xiaofang Liu, Yubang Wang, Bowen Zheng, Chengzhong Xing, Naijin Zhang, Jingwei Liu

Prognostic value of IDH2R140 and IDH2R172 mutations in patients with acute myeloid leukemia: a systematic review and meta-analysis

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Yao Qin, Kai Shen, Ting Liu, Hongbing Ma

Pan-cancer analysis of TASL: a novel immune infiltration-related biomarker for tumor prognosis and immunotherapy response prediction

• Open Access
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Huanyu Li, Xiaoyu Sun, Yanyun Zhao, Changzhu Zhang, Kai Jiang, Jie Ren, Lijuan Xing, Miao He

Two machine learning-based nomogram to predict risk and prognostic factors for liver metastasis from pancreatic neuroendocrine tumors: a multicenter study

• Open Access
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Jianbo Li, Long Huang, Chengyu Liao, Guozhong Liu, Yifeng Tian, Shi Chen

Prognostic value of tumor necrosis based on the evaluation of frequency in invasive breast cancer

• Open Access
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Jianhua Chen, Zhijun Li, Zhonghua Han, Deyong Kang, Jianli Ma, Yu Yi, Fangmeng Fu, Wenhui Guo, Liqin Zheng, Gangqin Xi, Jiajia He, Lida Qiu, Lianhuang Li, Qingyuan Zhang, Chuan Wang, Jianxin Chen

Adult breast, lung, pancreatic, upper and lower gastrointestinal cancer patients with hospitalized venous thromboembolism in the national French hospital discharge database

• Open Access
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F. Couturaud, I. Mahé, J. Schmidt, J-C. Gleize, T. Lafon, A. Saighi, F. Sedjelmaci, L. Bertoletti, P. Mismetti

An eHealth symptom and complication management program for cancer patients with newly created ostomies and their caregivers (Alliance): a pilot feasibility randomized trial

• Open Access
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Shenmeng Xu, Xianming Tan, Chunxuan Ma, Rebecca S. McElyea, Karl Shieh, Angela M. Stover, Angela Smith, Karyn Stitzenberg, Ethan Basch, Lixin Song

Cancer-specific survival in patients with cholangiocarcinoma after radical surgery: a Novel, dynamic nomogram based on clinicopathological features and serum markers

• Open Access
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Shurui Zhou, Yue Zhao, Yanzong Lu, Weiling Liang, Jianmin Ruan, Lijun Lin, Haoming Lin, Kaihong Huang

An integrated model for prognosis in vulvar squamous cell carcinoma

• Open Access
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Tao Zhang, Yingfan Zhu, Jie Luo, Juanqing Li, Shuang Niu, Hao Chen, Feng Zhou

Relationship between SUVmax on 18F-FDG PET and PD-L1 expression in liver metastasis lesions after colon radical operation

• Open Access
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Yan Qiao, Xiaomeng Li, Yongquan Hu, Pu Guo, Hengchao Liu, Hong Sun

Clinical implications of micro lymph node metastasis for patients with gastric cancer

• Open Access
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Yuan Tian, Yue Pang, Pei-Gang Yang, Hong-Hai Guo, Yang Liu, Ze Zhang, Ping-An Ding, Tao Zheng, Yong Li, Li-Qiao Fan, Zhi-Dong Zhang, Dong Wang, Xue-Feng Zhao, Bi-Bo Tan, Yu Liu, Qun Zhao

Predicting acute radiation dermatitis in breast cancer: a prospective cohort study

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Yuxiu Xie, Ting Hu, Renwang Chen, Haiyan Chang, Qiong Wang, Jing Cheng

Real-world effectiveness of third-line cabazitaxel in patients with metastatic castration-resistant prostate cancer: CARD-like analysis of data from a post-marketing surveillance in Japan

• Open Access
• Research

Hideyasu Matsuyama, Nobuaki Matsubara, Hirotaka Kazama, Takeshi Seto, Yoshinori Sunaga, Kazuhiro Suzuki

The CHASIT study: sequential chemo-immunotherapy in patients with locally advanced urothelial cancer – a non-randomized phase II clinical trial

• Open Access
• Study Protocol

V. C. Rutten, Y. Salhi, G. J. Robbrecht, R. de Wit, G. J.L.H. van Leenders, T. C.M. Zuiverloon, J. L. Boormans

Lung cancer multi-omics digital human avatars for integrating precision medicine into clinical practice: the LANTERN study

• Open Access
• Study Protocol

Filippo Lococo, Luca Boldrini, Charles-Davies Diepriye, Jessica Evangelista, Camilla Nero, Sara Flamini, Angelo Minucci, Elisa De Paolis, Emanuele Vita, Alfredo Cesario, Salvatore Annunziata, Maria Lucia Calcagni, Marco Chiappetta, Alessandra Cancellieri, Anna Rita Larici, Giuseppe Cicchetti, Esther G.C. Troost, Róza Ádány, Núria Farré, Ece Öztürk, Dominique Van Doorne, Fausto Leoncini, Andrea Urbani, Rocco Trisolini, Emilio Bria, Alessandro Giordano, Guido Rindi, Evis Sala, Giampaolo Tortora, Vincenzo Valentini, Stefania Boccia, Stefano Margaritora, Giovanni Scambia

HYpofractionated, dose-redistributed RAdiotherapy with protons and photons to combat radiation-induced immunosuppression in head and neck squamous cell carcinoma: study protocol of the phase I HYDRA trial

• Open Access
• Study Protocol

Joris B. W. Elbers, Pascal A. Gunsch, Reno Debets, Stijn Keereweer, Esther van Meerten, Jaap Zindler, Yvette van Norden, Mischa S. Hoogeman, Gerda M. Verduijn, Michiel Kroesen, Remi A. Nout

Retraction Note: BCORL1 is an independent prognostic marker and contributes to cell migration and invasion in human hepatocellular carcinoma

• Open Access
• Retraction Note

Guozhi Yin, Zhikui Liu, Yufeng Wang, Changwei Dou, Chao Li, Wei Yang, Yingmin Yao, Qingguang Liu, Kangsheng Tu

The INFINITY study protocol: a retrospective cohort study on decision making and clinical impact of biomarker-driven precision oncology in routine clinical practice

• Open Access
• Study protocol

Uwe M. Martens, Jan Schröder, Fee Bengsch, Ludger Sellmann, Sabine Busies, Stefanie Frank-Gleich, Matthias Zaiss, Thomas Decker, Andreas Schneeweiss, Martin Schuler, Sina Grebhardt, Stefan Zacharias, Norbert Marschner, Benjamin Kasenda, Karin Potthoff, Corinne Vannier

Use of Bevacizumab in recurrent glioblastoma: a scoping review and evidence map

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Minjie Fu, Zhirui Zhou, Xiao Huang, Zhenchao Chen, Licheng Zhang, Jinsen Zhang, Wei Hua, Ying Mao

Risk of retinal vein occlusion in colorectal cancer patients receiving anti-vascular endothelial growth factors – a population-based cohort study

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Wan-Ju Annabelle Lee, Wei-Pang Chung, Shih-Chieh Shao, Edward Chia-Cheng Lai, Yi-Chen Chen, Chung-Han Ho

A multi-centre randomized controlled trial investigating Consolidation Chemotherapy with and without oxaliplatin in distal rectal cancer and Watch & Wait

• Open Access
• Study protocol

Angelita Habr-Gama, Guilherme Pagin São Julião, Cinthia D. Ortega, Bruna Borba Vailati, Sergio Araujo, Thiago Jorge, Jorge Sabbaga, Gustavo L. Rossi, Renata D’Alpino, Fabio Roberto Kater, Patricia Bailão Aguilar, Adrian Mattacheo, Rodrigo Oliva Perez

Combination of alpha-fetoprotein and neutrophil-to-lymphocyte ratio to predict treatment response and survival outcomes of patients with unresectable hepatocellular carcinoma treated with immune checkpoint inhibitors

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Hong-Fei Zhu, Jin-Kai Feng, Yan-Jun Xiang, Kang Wang, Li-Ping Zhou, Zong-Han Liu, Yu-Qiang Cheng, Jie Shi, Wei-Xing Guo, Shu-Qun Cheng

Establishment and validation of a nomogram based on coagulation parameters to predict the prognosis of pancreatic cancer

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Peng Yunpeng, Yin Lingdi, Zhu Xiaole, Huang Dongya, Hu Le, Lu Zipeng, Zhang Kai, Hou Chaoqun, Miao Yi, Guo Feng, Li Qiang

Characterization and clinical verification of immune-related genes in hepatocellular carcinoma to aid prognosis evaluation and immunotherapy

• Open Access
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Jialin Qu, Fenghao Sun, Yichen Hou, Haoran Qi, Xiaorong Sun, Ligang Xing

Eukaryotic initiation factor 4 A-3 promotes glioblastoma growth and invasion through the Notch1-dependent pathway

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Lei Wei, Mika Pan, Qiulan Jiang, Beiquan Hu, Jianyi Zhao, Chun Zou, Liechun Chen, Chunhai Tang, Donghua Zou

Molecular and clinical characterization of PTRF in glioma via 1,022 samples

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Si Sun, Changlin Yang, Kuanyu Wang, Ruoyu Huang, Ke-nan Zhang, Yanwei Liu, Zhi Cao, Zheng Zhao, Tao Jiang

A randomized phase II study of full dose gemcitabine versus reduced dose gemcitabine and nab-paclitaxel in vulnerable patients with non-resectable pancreatic cancer (DPCG-01)

• Open Access
• Study Protocol

Louise Skau Rasmussen, Stine B. Winther, Inna M. Chen, Britta Weber, Lise Ventzel, Gabor Liposits, Julia Sidenius Johansen, Sönke Detlefsen, Ida Egendal, Susy Shim, Signe Christensen, Per Pfeiffer, Morten Ladekarl

Treatment decisions and the use of MEK inhibitors for children with neurofibromatosis type 1-related plexiform neurofibromas

• Open Access
• Review

Amy E. Armstrong, Allan J. Belzberg, John R. Crawford, Angela C. Hirbe, Zhihong J. Wang

Personalized follow-up of circulating DNA in resected stage III/IV melanoma: PERCIMEL multicentric prospective study protocol

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• Study Protocol

Lionnel Geoffrois, Alexandre Harlé, Nassim Sahki, Aleksandra Sikanja, Florence Granel-Brocard, Alice Hervieu, Laurent Mortier, Géraldine Jeudy, Catherine Michel, Charlée Nardin, Cécile Huin-Schohn, Jean-Louis Merlin

Metabolic syndrome and the risk of severe cancer events: a longitudinal study in Japanese workers

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Dong Van Hoang, Yosuke Inoue, Ami Fukunaga, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Hiroko Okazaki, Makoto Yamamoto, Toshiaki Miyamoto, Naoki Gommori, Takeshi Kochi, Taiki Shirasaka, Masafumi Eguchi, Takayuki Ogasawara, Kenya Yamamoto, Maki Konishi, Nobumi Katayama, Isamu Kabe, Seitaro Dohi, Tetsuya Mizoue

Nomogram for predicting survival in patients with advanced hepatocellular carcinoma treated with PD-1 inhibitors: incorporating pre-treatment and post-treatment clinical parameters

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Guhe Jia, Lupeng Qiu, Hongye Zheng, Boyu Qin, Zhuoya Sun, Yangyang Shao, Zizhong Yang, Jiakang Shao, Yuxin Zhou, Shunchang Jiao

MicroRNA-5195-3p mediated malignant biological behaviour of insulin-resistant liver cancer cells via SOX9 and TPM4

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Jing Yan, Bei Xie, Ye Tian, Wenqin An, Zhiheng Peng, Zhuan Liu, Jing Li, Linjing Li

Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis

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Zahra Maleki, Mohebat Vali, Hossein-Ali Nikbakht, Soheil Hassanipour, Aida Kouhi, Saman Sedighi, Roya Farokhi, Haleh Ghaem

Galectin-1 promotes gastric cancer peritoneal metastasis through peritoneal fibrosis

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Xianhe Shen, Huilan Liu, Haihua Zhou, Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Rongrong Dou, Fuxing Liu, Xiaolan You

Comprehensive analysis identifies cuproptosis-related gene DLAT as a potential prognostic and immunological biomarker in pancreatic adenocarcinoma

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Xiaoling Zhang, Yuxin Zhou, Jiahe Hu, Xuefeng Yu, Haitao Xu, Zhichang Ba, Haoxin Zhang, Yanan Sun, Rongfang Wang, Xinlian Du, Ruishu Mou, Xuedong Li, Jiuxin Zhu, Rui Xie

Ramucirumab plus irinotecan / leucovorin / 5-FU versus ramucirumab plus paclitaxel in patients with advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed one prior line of palliative chemotherapy: the phase II/III RAMIRIS study (AIO-STO-0415)

• Open Access
• Study protocol

Sylvie Lorenzen, Alix Schwarz, Claudia Pauligk, Eray Goekkurt, Gertraud Stocker, Jorge Riera Knorrenschild, Gerald Illerhaus, Tobias Dechow, Markus Moehler, Jean-Charles Moulin, Daniel Pink, Michael Stahl, Marina Schaaf, Thorsten Oliver Goetze, Salah-Eddin Al-Batran

A body shape index (ABSI) is associated inversely with post-menopausal progesterone-receptor-negative breast cancer risk in a large European cohort

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Sofia Christakoudi, Konstantinos K. Tsilidis, Laure Dossus, Sabina Rinaldi, Elisabete Weiderpass, Christian S. Antoniussen, Christina C. Dahm, Anne Tjønneland, Lene Mellemkjær, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Giovanna Masala, Sara Grioni, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Anne M. May, Evelyn M. Monninkhof, J. Ramón Quirós, Catalina Bonet, Maria-Jose Sánchez, Pilar Amiano, María-Dolores Chirlaque, Marcela Guevara, Ann H. Rosendahl, Tanja Stocks, Aurora Perez-Cornago, Sandar Tin Tin, Alicia K. Heath, Elom K. Aglago, Laia Peruchet-Noray, Heinz Freisling, Elio Riboli

The epidemiology of haematological cancers in Sarawak, Malaysia (1996 to 2015)

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Jew Win Kuan, Anselm Ting Su, Mastulu Wahab, Abdullah Hamdan, Jamilah Hashim, Andrew Kiyu, Choo Huck Ooi

Primary non-response to antiviral therapy affects the prognosis of hepatitis B virus-related hepatocellular carcinoma

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Peng Wang, Xinhui Wang, Xiaoli Liu, Fengna Yan, Huiwen Yan, Dongdong Zhou, Lihua Yu, Xianbo Wang, Zhiyun Yang

Safety and effectiveness of pembrolizumab monotherapy in Japanese patients with unresectable urothelial carcinoma: a nation-wide post-marketing surveillance

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Hiroyuki Nishiyama, Yu Tanaka, Masahiro Hamada, Masahiko Ozaki, Toshihiko Minegishi, Yuichiro Ito, Shinichiroh Maekawa, Nobuyuki Yamamoto

Hemoglobinopathies, merozoite surface protein-2 gene polymorphisms, and acquisition of Epstein Barr virus among infants in Western Kenya

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Perez K. Olewe, Shehu Shagari Awandu, Elly O. Munde, Samuel B. Anyona, Evans Raballah, Asito S. Amolo, Sidney Ogola, Erick Ndenga, Clinton O. Onyango, Rosemary Rochford, Douglas J. Perkins, Collins Ouma

Treatment patterns of targeted and nontargeted therapies and survival effects in patients with locally advanced head and neck cancer in Taiwan

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Szu-Han Hu, Ming-Yii Huang, Chung-Yu Chen, Hui-Min Hsieh

Survival outcomes and prognostic factors for first-line abiraterone acetate or enzalutamide in patients with metastatic castration-resistant prostate cancer

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Chi-Shin Tseng, Jui-Han Yang, Shi-Wei Huang, Yu-Jen Wang, Chung-Hsin Chen, Yeong-Shiau Pu, Jason Chia-Hsien Cheng, Chao-Yuan Huang

E-cadherin expression in the tumor microenvironment of advanced epidermal growth factor receptor-mutant lung adenocarcinoma and the association with prognosis

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Yu-Ping Chang, Gong-Kai Huang, Yung-Che Chen, Kuo-Tung Huang, Yu-Mu Chen, Chiung-Yu Lin, Chao-Cheng Huang, Meng-Chih Lin, Chin-Chou Wang

A randomized controlled trial using surgical gloves to prevent chemotherapy-induced peripheral neuropathy by paclitaxel in breast cancer patients (AIUR trial)

• Open Access
• Study Protocol

Young-Joon Kang, Chang Ik Yoon, Yun-Jung Yang, Jong Min Baek, Yong-Seok Kim, Ye Won Jeon, Jiyoung Rhu, Jae Pak Yi, Dooreh Kim, Se Jeong Oh

Mastectomy with Reconstruction Including Robotic Endoscopic Surgery (MARRES): a prospective cohort study of the Korea Robot-Endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG) and Korean Breast Cancer Study Group (KBCSG)

• Open Access
• Study protocol

Jai Min Ryu, Jeea Lee, Jeeyeon Lee, BeomSeok Ko, Joo Heung Kim, Hyukjai Shin, Hyung Seok Park

Association of pre-treatment lymphocyte-monocyte ratio with survival outcome in patients with head and neck cancer treated with chemoradiation

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Brian Yu, Sung Jun Ma, Michael Khan, Jasmin Gill, Austin Iovoli, Fatemeh Fekrmandi, Mark K. Farrugia, Kimberly Wooten, Vishal Gupta, Ryan McSpadden, Moni A. Kuriakose, Michael R. Markiewicz, Ayham Al-Afif, Wesley L. Hicks Jr., Mukund Seshadri, Andrew D. Ray, Elizabeth A. Repasky, Anurag K. Singh

PSMD8 can serve as potential biomarker and therapeutic target of the PSMD family in ovarian cancer: based on bioinformatics analysis and in vitro validation

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Xiao Li, Xinru Li, Yuexin Hu, Ouxuan Liu, Yuxuan Wang, Siting Li, Qing Yang, Bei Lin

Prognostic models for upper urinary tract urothelial carcinoma patients after radical nephroureterectomy based on a novel systemic immune-inflammation score with machine learning

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Jianyong Liu, Pengjie Wu, Shicong Lai, Jianye Wang, Huimin Hou, Yaoguang Zhang

Characterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer

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Carolin Schimmelpfennig, Michael Rade, Susanne Füssel, Dennis Löffler, Conny Blumert, Catharina Bertram, Angelika Borkowetz, Dominik J. Otto, Sven-Holger Puppel, Pia Hönscheid, Ulrich Sommer, Gustavo B. Baretton, Ulrike Köhl, Manfred Wirth, Christian Thomas, Friedemann Horn, Markus Kreuz, Kristin Reiche

Malnutrition and visceral obesity predicted adverse short-term and long-term outcomes in patients undergoing proctectomy for rectal cancer

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Chong-Jun Zhou, Yi Lin, Jie-Yu Liu, Zhong-Lin Wang, Xi-Yi Chen, Chen-Guo Zheng

Photon and Proton irradiation in Patient-derived, Three-Dimensional Soft Tissue Sarcoma Models

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Siyer Roohani, Jürgen Loskutov, Jens Heufelder, Felix Ehret, Lena Wedeken, Manuela Regenbrecht, Rica Sauer, Daniel Zips, Andrea Denker, Antonia M. Joussen, Christian R. A. Regenbrecht, David Kaul

Post-therapeutic circulating tumor cell-associated white blood cell clusters predict poor survival in patients with advanced driver gene-negative non-small cell lung cancer

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Ying Wang, Yanxia Liu, Zhiyun Zhang, Baohua Lu, Yuan Gao, Li Tong, Mingming Hu, Peter Ping Lin, Baolan Li, Tongmei Zhang

Tumor necrosis is an underappreciated histopathologic factor in the grading of chondrosarcoma

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Alexander L. Lazarides, Bijan Abar, Bruce Leckey, John T. Martin, Evelyna G. Kliassov, Brian E. Brigman, William C. Eward, Diana M. Cardona, Julia D. Visgauss

Predictive model for long-term weight recovery after gastrectomy for gastric cancer: an introduction to a web calculator

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Chul-Hyo Jeon, Ki Bum Park, Sojung Kim, Ho Seok Seo, Kyo Young Song, Han Hong Lee

Protocol for a prospective study evaluating circulating tumour cells status to predict radical prostatectomy treatment failure in localised prostate cancer patients (C-ProMeta-1)

• Open Access
• Study Protocol

Tarek Al-Hammouri, Ricardo Almeida-Magana, Rachel Lawrence, Tom Duffy, Laura White, Edwina Burke, Sakunthala Kudahetti, Justin Collins, Prabhakar Rajan, Daniel Berney, Rhian Gabe, Greg Shaw, Yong-Jie Lu

Correction: Invasion inhibition in pancreatic cancer using the oral iron chelating agent deferasirox

• Open Access
• Correction

Shogo Amano, Seiji Kaino, Shuhei Shinoda, Hirofumi Harima, Toshihiko Matsumoto, Koichi Fujisawa, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Isao Sakaida

Analysis of m7G-Related signatures in the tumour immune microenvironment and identification of clinical prognostic regulators in breast cancer

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Qinghua Huang, Jianlan Mo, Huawei Yang, Yinan Ji, Rong Huang, Yan Liu, You Pan

Interferon-induced transmembrane protein 3 in hepatocellular carcinoma patients

• Open Access
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Rania M. Bondok, Lamiaa A. Barakat, Alyaa R. Elsergany, Nancy Mahsoub, Maivel H. Ghattas

Impact of polypharmacy and comorbidity on survival and systemic parenteral treatment administration in a cohort of hospitalized lung-cancer patients

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Hélène Pluchart, Sébastien Bailly, Sébastien Chanoine, Denis Moro-Sibilot, Pierrick Bedouch, Anne-Claire Toffart

Expression profiles and functional prediction of histone acetyltransferases of the MYST family in kidney renal clear cell carcinoma

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Fan Liang, Xiangke Li, Xiaoman Shen, Runlei Yang, Chuan Chen

Unmet supportive care needs of breast cancer survivors: a systematic scoping review

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Rongrong Fan, Lili Wang, Xiaofan Bu, Wenxiu Wang, Jing Zhu

Fan beam CT-guided online adaptive external radiotherapy of uterine cervical cancer: a dosimetric evaluation

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Haibo Peng, Jie Zhang, Ningyue Xu, Yangang Zhou, Huigang Tan, Tao Ren

SLC25A32 promotes malignant progression of glioblastoma by activating PI3K-AKT signaling pathway

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Zhiwei Xue, Jiwei Wang, Zide Wang, Junzhi Liu, Jiangli Zhao, Xuchen Liu, Yan Zhang, Guowei Liu, Zhimin Zhao, Wenjie Li, Qing Zhang, Xingang Li, Bin Huang, Xinyu Wang

Decision-analytic evaluation of the comparative effectiveness and cost-effectiveness of strategies to prevent breast and ovarian cancer in German women with BRCA-1/2 mutations

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Lára R. Hallsson, Gaby Sroczynski, Jutta Engel, Uwe Siebert

Analysis of mRNA-miRNA interaction network reveals the role of CAFs-derived exosomes in the immune regulation of oral squamous cell carcinoma

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Wei-Zhou Wang, Xue Cao, Li Bian, Yue Gao, Ming Yu, Yi-Ting Li, Jian-Guo Xu, Yang-Hao Wang, He-Feng Yang, Ding-Yun You, Yong-Wen He

Neoadjuvant chemotherapy with modified FOLFOXIRI for locally advanced rectal cancer to transform effectively EMVI and MRF from positive to negative: results of a long-term single center phase 2 clinical trial

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Wen Zhang, Haitao Zhou, Jun Jiang, Yuelu Zhu, Shuangmei Zou, Liming Jiang, Yuan Tang, Jianwei Liang, Yongkun Sun, Zhichao Jiang, Wang Qu, Ying Li, Aiping Zhou

Integrated analysis of intratumoral biomarker and tumor-associated macrophage to improve the prognosis prediction in cancer patients

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Ming-Da Wang, Hao Xiang, Tian-Yu Hong, Abudurexiti Mierxiati, Fei-Hu Yan, Ling Zhang, Chao Wang

High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist

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Bingwei Ma, Xingchun Wang, Hui Ren, Yingying Li, Haijiao Zhang, Muqing Yang, Jiyu Li

A novel nomogram based on cell cycle-related genes for predicting overall survival in early-onset colorectal cancer

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Meijuan Xiang, Yuan Gao, Yue Zhou, Muqing Wang, Xueqing Yao

Integrated bioinformatics analysis and experimental validation reveal ISG20 as a novel prognostic indicator expressed on M2 macrophage in glioma

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Yaojun Peng, Hongyu Liu, Qiyan Wu, Lingxiong Wang, Yanju Yu, Fan Yin, Cong Feng, Xuewen Ren, Tianyi Liu, Ling Chen, Haiyan Zhu

Prognostic value of pre-therapeutic nutritional risk factors in elderly patients with locally advanced esophageal squamous cell carcinoma receiving definitive chemoradiotherapy or radiotherapy

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Jianjian Qiu, Jun Yang, Yilin Yu, Zhiping Wang, Hancui Lin, Dongmei Ke, Hongying Zheng, Jiancheng Li, Qiwei Yao

The trends in death of primary liver cancer caused by specific etiologies worldwide: results from the Global Burden of Disease Study 2019 and implications for liver cancer management

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Yongzhi Li, Zejin Ou, Danfeng Yu, Huan He, Liting Zheng, Jiaqi Chen, Caiyun Chen, Hushen Xiong, Qing Chen

Upregulation of dihydropyrimidinase-like 3 (DPYSL3) protein predicts poor prognosis in urothelial carcinoma

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Peir-In Liang, Hong-Yue Lai, Ti-Chun Chan, Wei-Ming Li, Chung-Hsi Hsing, Steven K. Huang, Kun-Lin Hsieh, Wen-Hsin Tseng, Tzu-Ju Chen, Wan-Shan Li, Huan-Da Chen, Yu-Hsuan Kuo, Chien-Feng Li

TACE sequential MWA guided by cone-beam computed tomography in the treatment of small hepatocellular carcinoma under the hepatic dome

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Zhaonan Li, Kaihao Xu, Xueliang Zhou, Dechao Jiao, Xinwei Han

The coagulation-related genes for prognosis and tumor microenvironment in pancreatic ductal adenocarcinoma

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Di Wang, Song-ping Cui, Qing Chen, Zhang-yong Ren, Shao-cheng Lyu, Xin Zhao, Ren Lang

Morusin shows potent antitumor activity for melanoma through apoptosis induction and proliferation inhibition

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Wei Liu, Yacong Ji, Feng Wang, Chongyang Li, Shaomin Shi, Ruochen Liu, Qian Li, Leiyang Guo, Yaling Liu, Hongjuan Cui

Treatment patterns and outcomes of patients with metastatic non-small cell lung cancer in five European countries: a real-world evidence survey

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Hollie Bailey, Adam Lee, Laura Eccles, Yong Yuan, Helen Burlison, Cameron Forshaw, Nebibe Varol

Aspartoacylase promotes the process of tumour development and is associated with immune infiltrates in gastric cancer

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Yalin Han, Xuning Wang, Maolin Xu, Zhipeng Teng, Rui Qin, Guodong Tan, Peng Li, Peng Sun, Hongyi Liu, Li Chen, Baoqing Jia

Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

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Iliana K. Kerzeli, Alexandros Kostakis, Polat Türker, Per-Uno Malmström, Tammer Hemdan, Artur Mezheyeuski, Douglas G. Ward, Richard T. Bryan, Ulrika Segersten, Martin Lord, Sara M. Mangsbo

Persistence to extended adjuvant endocrine therapy following Breast Cancer Index (BCI) testing in women with early-stage hormone receptor-positive (HR +) breast cancer

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• Research article

Julia Foldi, Anastasia Tsagianni, Max Salganik, Catherine A. Schnabel, Adam Brufsky, G. J. van Londen, Lajos Pusztai, Tara Sanft

FAM13A polymorphisms are associated with a specific susceptibility to clinical progression of oral cancer in alcohol drinkers

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Ming-Ju Hsieh, Yu-Sheng Lo, Yun-Jung Tsai, Hsin-Yu Ho, Chia-Chieh Lin, Yi-Ching Chuang, Shu-Hui Lin, Mu-Kuan Chen

An analysis of clinical characteristics and prognosis of endometrioid ovarian cancer based on the SEER database and two centers in China

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Shuangfeng Chen, Huaiwu Lu, Shan Jiang, Min Li, Haiyan Weng, Jing Zhu, Tianjiao Zhang, Yingying Wang, Weidong Zhao, Dabao Wu, Zhen Shen, Zhenye Yang, Ying Zhou

Prolonged usage of fosaprepitant for prevention of delayed chemotherapy-induced nausea and vomiting(CINV) in patients receiving highly emetogenic chemotherapy

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Ai Gao, Shasha Guan, Yinjuan Sun, Lingling Wang, Fanlu Meng, Xia Liu, Liyan Gu, Guo Li, Diansheng Zhong, Linlin Zhang

CA125 Levels in BRCA mutation carriers – a retrospective single center cohort study

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P Gebhart, CF Singer, D Gschwantler-Kaulich

RETRACTED ARTICLE: Upregulation of hsa_circ_0002003 promotes hepatocellular carcinoma progression

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Lisha Zhou, Qianwen Wang, Jun Hou, Xiangwei Wu, Lianghai Wang, Xueling Chen

Retraction Note: Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects

• Open Access
• Retraction Note

Hongwei Tian, Gang Shi, Guoyou Yang, Junfeng Zhang, Yiming Li, Tao Du, Jianzhou Wang, Fen Xu, Lin Cheng, Xiaomei Zhang, Lei Dai, Xiaolei Chen, Shuang Zhang, Yang Yang, Dechao Yu, Yuquan Wei, Hongxin Deng

Genomic landscapes of ovarian clear cell carcinoma from latin countries reveal aberrations linked to survival and progression

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Mariana de Paiva Batista, Martín Roffé, Ignacio Romero, José Antonio López-Guerrero, Carmen Illueca, Raquel Lopez, Alexandre André Balieiro Anastácio da Costa, Louise De Brot, Juan Pablo Molina, Laura Barboza, Fernanda Maris Peria, Fernando Chaud, Ana Silvia Gouvêa Yamada, Andres Poveda, Eduardo Magalhães Rego

A simple and available measurement of onco-sEV dsDNA to protein ratio as a potential tumor marker

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Yifan Sun, Miao Li, Xiaoshan Zhang, Dongjie Xu, Jie Wu, Xinrui Gu, Adeel Khan, Han Shen, Zhiyang Li

Association between insulin resistance and cardiac remodeling in HER2-positive breast cancer patients: a real-world study

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Yunjing Shi, Zeping Qiu, Jing Yu, Zhuojin Li, Sha Hua, Yanjia Chen, Xiaosong Chen, Kunwei Shen, Wei Jin

The role of heavy metals in the development of colorectal cancer

• Open Access
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Yongsheng Li, Jingwei Lou, Shaozhong Hong, Dengfeng Hou, Yandong Lv, Zhiqiang Guo, Kai Wang, Yue Xu, Yufeng Zhai, Hongzhou Liu

Optimized screening of DNA methylation sites combined with gene expression analysis to identify diagnostic markers of colorectal cancer

• Open Access
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Zhen Ye, Guangle Song, Jianwei Liang, Shuying Yi, Yuqi Gao, Hanming Jiang

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

• Open Access
• Research article

Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T. P. Verwiel, Douwe F. M. van der Leest, Lennart Kester, Jan J. Molenaar, Jules Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B. J. Tops, Frank C. P. Holstege, Patrick Kemmeren, Jayne Y. Hehir-Kwa

Pan-cancer analysis of whole-genome doubling and its association with patient prognosis

• Open Access
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Chie Kikutake, Mikita Suyama

Development and validation of prognostic nomograms based on De Ritis ratio and clinicopathological features for patients with stage II/III colorectal cancer

• Open Access
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Jinming Fu, Fenqi Du, Tian Tian, Hao Huang, Lei Zhang, Dapeng Li, Yupeng Liu, Ding Zhang, Lijing Gao, Ting Zheng, Yanlong Liu, Yashuang Zhao

Prediction of residual disease using circulating DNA detection after potentiated radiotherapy for locally advanced head and neck cancer (NeckTAR): a study protocol for a prospective, multicentre trial

• Open Access
• Study Protocol

Angeline Ginzac, Marie-Céleste Ferreira, Anne Cayre, Clément Bouvet, Julian Biau, Ioana Molnar, Nicolas Saroul, Nathalie Pham-Dang, Xavier Durando, Maureen Bernadach

Metabolic syndrome score as an indicator in a predictive nomogram for lymph node metastasis in endometrial cancer

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Xuan Feng, Xing Chen Li, Xiao Yang, Yuan Cheng, Yang Yang Dong, Jing Yuan Wang, Jing Yi Zhou, Jian Liu Wang

Family resilience and its influencing factors among advanced cancer patients and their family caregivers: a multilevel modeling analysis

• Open Access
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Panpan Cui, Jiaoxia Shi, Shifeng Li, Mikiyas Amare Getu, Ruibo Wang, Changying Chen

Triple modal treatment comprising with proton beam radiation, hyperthermia, and gemcitabine/nab-paclitaxel for locally advanced pancreatic cancer: a phase I/II study protocol (TT-LAP trial)

• Open Access
• Study protocol

Osamu Shimomura, Masato Endo, Hirokazu Makishima, Takeshi Yamada, Shinji Hashimoto, Haruko Numajiri, Yoshihiro Miyazaki, Manami Doi, Kinji Furuya, Kazuhiro Takahashi, Toshikazu Moriwaki, Naoyuki Hasegawa, Yoshiyuki Yamamoto, Yusuke Niisato, Mariko Kobayashi, Masashi Mizumoto, Kei Nakai, Takashi Saito, Sodai Hoshiai, Tsukasa Saida, Bryan J. Mathis, Kensaku Mori, Takahito Nakajima, Kiichiro Tsuchiya, Hideyuki Sakurai, Tatsuya Oda

Importance of endocrine treatment adherence and persistence in breast cancer survivorship: a systematic review

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Finn Magnus Eliassen, Vibeke Blåfjelldal, Thomas Helland, Cathrine Fonnesbech Hjorth, Kari Hølland, Lise Lode, Bjørn-Erik Bertelsen, Emiel A. M. Janssen, Gunnar Mellgren, Jan Terje Kvaløy, Håvard Søiland, Tone Hoel Lende

IL-8-induced CXCR2 down-regulation in circulating monocytes in hepatocellular carcinoma is partially dependent on MAGL

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Chong Zhong Liu, Xing Bao Liu, Jun Sun, Chao Qun Yu, Jing Chun Yao, Zhong Liu, Jing Cheng Hao

The impact of COVID-19 on national program of colorectal cancer screening in Tehran, Iran: a multicenter study

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Amir Sadeghi, Hamid Asadzadeh Aghdaei, Mohammad Amin Khalafi, Ehsan Nazemalhosseini-Mojarad, Pardis Ketabi Moghadam, Mohammad-Reza Sohrabi

GBAP1 functions as a tumor promotor in hepatocellular carcinoma via the PI3K/AKT pathway

• Open Access
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Rong Chen, Meng Zhao, Yanli An, Dongfang Liu, Qiusha Tang

Developing tumor-specific PRO-CTCAE item sets: analysis of a cross-sectional survey in three German outpatient cancer centers

• Open Access
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Maximilian Günther, Leopold Hentschel, Markus Schuler, Theresa Müller, Katharina Schütte, Yon-Dschun Ko, Ingo Schmidt-Wolf, Ulrich Jaehde

Expression of NEAT1 can be used as a predictor for Dex resistance in multiple myeloma patients

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Yuyue Ren, Yijun Liu, Wanting He, Weiwei Zhao, Jiaqi Pan, Haiyan Gao, Yuying Li, Ying Zhang, Wei Wang

Treatment compliance among adult cervical cancer patients receiving care at Uganda cancer institute, Uganda: a retrospective data review

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Josephine Irene Najjemba, Regina Ndagire, Pius Mulamira, Solomon Kibudde, Catherine Nassozi Lwanira

Promoting physical activity through supervised vs motivational behavior change interventions in breast cancer survivors on aromatase inhibitors (PAC-WOMAN): protocol for a 3-arm pragmatic randomized controlled trial

• Open Access
• Study Protocol

Eliana V. Carraça, Bruno Rodrigues, Sofia Franco, Inês Nobre, Flávio Jerónimo, Vítor Ilharco, Fernanda Gabriel, Leonor Ribeiro, António L. Palmeira, Marlene N. Silva

Assessing awareness of blood cancer symptoms and barriers to symptomatic presentation: measure development and results from a population survey in the UK

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Laura Boswell, Jenny Harris, Athena Ip, Jessica Russell, Georgia B Black, Katriina L Whitaker

Single-organ pulmonary metastasis is a favorable prognostic factor in metastatic colorectal cancer patients treated with FOLFIRI and vascular endothelial growth factor inhibitors

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Koshiro Fukuda, Hiroki Osumi, Koichiro Yoshino, Izuma Nakayama, Shota Fukuoka, Mariko Ogura, Takeru Wakatsuki, Akira Ooki, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi, Eiji Shinozaki

Efficacy and safety of atezolizumab plus bevacizumab treatment for advanced hepatocellular carcinoma in the real world: a single-arm meta-analysis

• Open Access
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Xiaoqiang Gao, Rui Zhao, Huaxing Ma, Shi Zuo

Retraction Note: A synthetic dsRNA, as a TLR3 pathwaysynergist, combined with sorafenib suppresses HCC in vitro and in vivo

• Open Access
• Retraction Note

Yu-Yin Xu, Li Chen, Gui-Lan Wang, Jia-Ming Zhou, Yi-Xin Zhang, Yin-Ze Wei, Yuan-Yuan Zhu, Jing Qin

S100A family is a group of immune markers associated with poor prognosis and immune cell infiltration in hepatocellular carcinoma

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Yuchen Qi, Yujing Zhang, Jianwen Li, Mengting Cai, Bo Zhang, Zhangtao Yu, Yuhang Li, Junkai Huang, Xu Chen, Yinghui Song, Sulai Liu

Deep learning–based radiomic nomograms for predicting Ki67 expression in prostate cancer

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Shuitang Deng, Jingfeng Ding, Hui Wang, Guoqun Mao, Jing Sun, Jinwen Hu, Xiandi Zhu, Yougen Cheng, Genghuan Ni, Weiqun Ao

A phase II study of gemcitabine and docetaxel combination in relapsed metastatic or unresectable locally advanced synovial sarcoma

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Ghazal Tansir, Sameer Rastogi, Akash Kumar, Adarsh Barwad, Asit R. Mridha, Ekta Dhamija, Shamim A. Shamim, Sushma Bhatnagar, Sandeep Bhoriwal

The impact of sarcopenia on the outcome of patients with left-sided colon and rectal cancer after curative surgery

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Qi Li, Tailai An, Jianbin Wu, Weiqi Lu, Yan Wang, Jia Li, Lina Yang, Yiqi Chen, Lizhu Lin, Zhenjiang Yang

An integrative bioinformatics investigation and experimental validation of chromobox family in diffuse large B-cell lymphoma

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Fenling Zhou, Lu Chen, Peng Lu, Yuli Cao, Cuilan Deng, Gexiu Liu

Use of period analysis to provide a timely assessment of 5-year relative survival for pancreatic cancer patients from Taizhou, eastern China

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Ye Lu, Min He, Liyou Lian, Huijun Lei, Yongran Cheng, Liangyou Wang, Tianhui Chen, Jinfei Chen

The association between prescription drugs and colorectal cancer prognosis: a nationwide cohort study using a medication-wide association study

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Hyeong-Taek Woo, Seung-Yong Jeong, Aesun Shin

Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis

• Open Access
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Xihua Mao, Chioma Omeogu, Shama Karanth, Ashwini Joshi, Clare Meernik, Lauren Wilson, Amy Clark, April Deveaux, Chunyan He, Tisha Johnson, Karen Barton, Samantha Kaplan, Tomi Akinyemiju

The effect of specimen processing time on HER2 expression in gastric cancer and esophagogastric junction cancer: a single-center retrospective observational study

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Yoshitomo Yanagimoto, Hiroshi Imamura, Shiro Adachi, Kazuki Odagiri, Tomono Kawase, Masafumi Yamashita, Hiroshi Takeyama, Yozo Suzuki, Masakazu Ikenaga, Junzo Shimizu, Naohiro Tomita, Keizo Dono

Associations between detectable circulating tumor DNA and tumor glucose uptake measured by 18F-FDG PET/CT in early-stage non-small cell lung cancer

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• Research

Anine Larsen Ottestad, Håkon Johansen, Tarje Onsøien Halvorsen, Hong Yan Dai, Sissel Gyrid Freim Wahl, Elisabeth Fritzke Emdal, Bjørn Henning Grønberg

Identifying important microbial and genomic biomarkers for differentiating right- versus left-sided colorectal cancer using random forest models

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Tyler Kolisnik, Arielle Kae Sulit, Sebastian Schmeier, Frank Frizelle, Rachel Purcell, Adam Smith, Olin Silander

The PRO-RCC study: a long-term PROspective Renal Cell Carcinoma cohort in the Netherlands, providing an infrastructure for ‘Trial within Cohorts’ study designs

• Open Access
• Study Protocol

Hilin Yildirim, Christiaan V Widdershoven, Maureen JB Aarts, Axel Bex, Haiko J Bloemendal, Deirdre M Bochove-Overgaauw, Paul Hamberg, Karin H Herbschleb, Tom van der Hulle, Brunolf W Lagerveld, Martijn GH van Oijen, Sjoukje F Oosting, Johannes V van Thienen, Astrid AM van der Veldt, Hans M Westgeest, Evelijn E Zeijdner, Katja KH Aben, Corina van den Hurk, Patricia J Zondervan, Adriaan D Bins

Immune regulation and prognosis indicating ability of a newly constructed multi-genes containing signature in clear cell renal cell carcinoma

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Ziwei Gui, Juan Du, Nan Wu, Ningning Shen, Zhiqing Yang, Huijun Yang, Xuzhi Wang, Na Zhao, Zixin Zeng, Rong Wei, Wenxia Ma, Chen Wang

Next-generation sequencing reveals mitogenome diversity in plasma extracellular vesicles from colorectal cancer patients

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• Research article

Tonje Bjørnetrø, Paula A. Bousquet, Kathrine Røe Redalen, Anne-Marie Siebke Trøseid, Torben Lüders, Espen Stang, Adriana M. Sanabria, Christin Johansen, Anniken Jørlo Fuglestad, Christian Kersten, Sebastian Meltzer, Anne Hansen Ree

Valero’s host index is useful in predicting radiation-induced trismus and osteoradionecrosis of the jaw risks in locally advanced nasopharyngeal carcinoma patients

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Erkan Topkan, Efsun Somay, Busra Yilmaz, Berrin Pehlivan, Ugur Selek

RUNX3 regulates the susceptibility against EGFR-targeted non-small cell lung cancer therapy using 47Sc-conjugated cetuximab

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Da-Mi Kim, So-Young Lee, Jae-Cheong Lim, Eun-Ha Cho, Ul-Jae Park

Failure to follow up abnormal test results associated with cervical cancer in primary and ambulatory care: a systematic review

• Open Access
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Javiera Martinez-Gutierrez, Sophie Chima, Lucy Boyd, Asma Sherwani, Allison Drosdowsky, Napin Karnchanachari, Vivien Luong, Jeanette C. Reece, Jon Emery

An extensive study of potential inhibitors of extracellular vesicles release in triple-negative breast cancer

• Open Access
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Niamh McNamee, Mariadelva Catalano, Anindya Mukhopadhya, Lorraine O’Driscoll

Management of metastatic melanoma in Texas: disparities in the utilization of immunotherapy following the regulatory approval of immune checkpoint inhibitors

• Open Access
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Olajumoke A. Olateju, Zhen Zeng, J. Douglas Thornton, Osaro Mgbere, Ekere James Essien

HER2-low breast cancer: evolution of HER2 expression from primary tumor to distant metastases

• Open Access
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Mengyuan Cai, Ming Li, Hong Lv, Shuling Zhou, Xiaoli Xu, Ruohong Shui, Wentao Yang

Percutaneous transhepatic cholangial drainage or antibiotic therapy worsens response to immunotherapy in advanced cholangiocarcinoma

• Open Access
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Qingyu Huang, Fuhao Wang, Xiang Zhang, Jing Liu, Xue Dou, Rui Feng, Kunli Zhu, Shumei Jiang, Yun Zhang, Jinbo Yue

Risk factors for postoperative recurrence in patients with stage II colorectal cancer

• Open Access
• Research article

Zhi-Zhong Xiong, Ming-Hao Xie, Xian-Zhe Li, Long-Yang Jin, Feng-Xiang Zhang, Shi Yin, Hua-Xian Chen, Lei Lian

Common driver mutations and programmed death-ligand 1 expression in advanced non-small cell lung cancer in smokers and never smokers

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Chong Kin LIAM, Chian Yih YEW, Yong Kek PANG, Chee Kuan WONG, Mau Ern POH, Jiunn Liang TAN, Chun Ian SOO, Thian Chee LOH, Ka Kiat CHIN, Vijayan MUNUSAMY, Yong Sheng LIAM, Nur Husna IBRAHIM

A necroptosis-related gene signature to predict prognosis and immune features in hepatocellular carcinoma

• Open Access
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Kai Zhang, Jinpeng Li, Enwu Yuan

Immune inactivation by VISTA predicts clinical outcome and therapeutic benefit in muscle-invasive bladder cancer

• Open Access
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Wandi Li, Zhaopei Liu, Kaifeng Jin, Fei Shao, Han Zeng, Yiwei Wang, Yu Zhu, Le Xu, Zewei Wang, Yuan Chang, Weijuan Zhang

Glioma angiogenesis is boosted by ELK3 activating the HIF-1/VEGF-A signaling axis

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Mou Yueyang, Hu Yaqin, Xue Guolian, Zhao Wenjian, Jiao Yang, Li Chen, Cao Haiyan, Chao Min, Deng Jianping, Dai Penggao, Zhu Hongli, Wang Liang

Efficacy of second-line chemotherapy or immune checkpoint inhibitors for patients with a prolonged objective response (≥ 6 months) after first-line therapy for recurrent or metastatic head and neck squamous cell carcinoma: a retrospective study

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Agathe Vienne, Laetitia Collet, Thomas Chevalier, Christian Borel, Magalie Tardy, Florence Huguet, Sandrine Richard, Sebastien Salas, Esma Saada-Bouzid, Jerome Fayette, Amaury Daste

Factors associated with health-related quality of life in a cohort of cancer survivors in New Jersey

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Sharon Manne, Katie Devine, Shawna Hudson, Deborah Kashy, Denalee O’Malley, Lisa E. Paddock, Elisa V. Bandera, Adana A. M. Llanos, Angela Fong, Neetu Singh, Sara Frederick, Andrew M. Evens

A population-based cohort study on changes in breast, lung and colorectal cancer incidence and mortality among non-Western immigrant women

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Maarit Lamminmäki, Aku Leivonen, Sirpa Heinävaara, Mari Nygård, Giske Ursin, Suzanne Campbell, Hrefna Stefansdóttir, Elli Hirvonen, Salla Toikkanen, Ilse Merete Munk Vejborg, Sisse Helle Njor, Tytti Sarkeala

Retraction Note: Hsa_circ_0005379 regulates malignant behavior of oral squamous cell carcinoma through the EGFR pathway

• Open Access
• Retraction Note

Wen Su, Yufan Wang, Feng Wang, Shuai Sun, Minghua Li, Yuehong Shen, Hongyu Yang

The QUILT study: quilting sutures in patients undergoing breast cancer surgery: a stepped wedge cluster randomized trial study

• Open Access
• Study protocol

L. J. van Zeelst, B. ten Wolde, J. D. J. Plate, J. H. Volders, R.R.J.P. van Eekeren, A. Doeksen, M. L. Hoven-Gondrie, A. F. T. Olieman, Y. E. A. van Riet, A. P. Schouten van der Velden, S. Vijfhuize, H. H. G. Witjes, J. H. W. de Wilt, L. J. A. Strobbe

MicroRNA-191 regulates oral squamous cell carcinoma cells growth by targeting PLCD1 via the Wnt/β-catenin signaling pathway

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Zekun Wang, Wenzhao Guan, Yufeng Ma, Xuedong Zhou, Guohua Song, Jianing Wei, Chenyang Wang

High NANOG expression correlates with worse patients’ survival in esophageal adenocarcinoma

• Open Access
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Karl Knipper, Alexander I. Damanakis, Su Ir Lyu, Adrian Georg Simon, Isabell Wahler, Christiane J. Bruns, Wolfgang Schröder, Thomas Schmidt, Alexander Quaas

Serum brain-derived neurotrophic factor (BDNF) as predictors of childhood neuroblastoma relapse

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Xilin Xiong, Meiling Zeng, Xiaomin Peng, Chuchu Feng, Chunmou Li, Wenjun Weng, Yang Li

Elevated FAM134B expression induces radiation-sensitive in hepatocellular carcinoma

• Open Access
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Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu, Heping Li

SNHG1 opposes quiescence and promotes docetaxel sensitivity in prostate cancer

• Open Access
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Steven P. Zielske, Wei Chen, Kristina G. Ibrahim, Frank C. Cackowski

Prognostic value of EBV DNA and platelet-to-lymphocyte ratio in patients with non-metastatic nasopharyngeal carcinoma: a retrospective study

• Open Access
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Huan Dong, Zichong Huang, Dong Yang, Zhiru Li, Heqing Huang, Zhen Meng, Yutao Qin, Min Kang

Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family

• Open Access
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Li-Hui Wang, Bo Cao, Yun-Long Li, Bao-Ping Qiao

Combining perineural invasion with staging improve the prognostic accuracy in colorectal cancer: a retrospective cohort study

• Open Access
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Bin Zhang, Yanyun Lin, Chao Wang, Zexian Chen, Tianze Huang, Hao Chen, Guannan Wang, Ping Lan, Xiaowen He, Xiaosheng He

Sintilimab plus bevacizumab and CapeOx (BBCAPX) on first-line treatment in patients with RAS mutant, microsatellite stable, metastatic colorectal cancer: study protocol of a randomized, open-label, multicentric study

• Open Access
• Study Protocol

Xuefeng Fang, Chenhan Zhong, Shanshan Weng, Hanguang Hu, Jian Wang, Qian Xiao, Jianwei Wang, Lifeng Sun, Dong Xu, Xiujun Liao, Caixia Dong, Suzhan Zhang, Jun Li, Kefeng Ding, Ying Yuan

Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma

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Yize Zhang, Xue Liang, Qinghai Lian, Liwen Liu, Baoyu Zhang, Zihui Dong, Kunpeng Liu

Persistent high levels of carcinoembryonic antigen after tumor resection are associated with poorer survival outcomes in patients with resected colon cancer

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Wendy R. Muñoz-Montaño, Horacio N. López-Basave, Alison Castillo-Morales, Carolina Castillo-Morales, Karen Sánchez-Trejo, Rodrigo Catalán, Consuelo Díaz-Romero, Leonardo S. Lino-Silva, Andrea Maliachi-Díaz, Erika Ruiz-García, Marytere Herrera-Martínez, German Calderillo-Ruíz

RFID trial: localization of non-palpable breast lesions using radiofrequency identification tags or wire

• Open Access
• Study protocol

Hugo Veyssiere, Margot Dressaire, Raphaël Pete, Céleste Pinard, Ioana Molnar, Catherine Abrial, Angeline Ginzac, Xavier Durando, Marielle Tekath

Nanoparticle delivery of TFOs is a novel targeted therapy for HER2 amplified breast cancer

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Xiaojing Yang, Yi Xu, Jie Fu, Zan Shen

Predictive and prognostic markers from endoscopic ultrasound with biopsies during definitive chemoradiation therapy in esophageal squamous cell carcinoma

• Open Access
• Research

Qingwu Du, Xiaoyue Wu, Kunning Zhang, Fuliang Cao, Gang Zhao, Xiaoying Wei, Zhoubo Guo, Yang Li, Jie Dong, Tian Zhang, Wencheng Zhang, Ping Wang, Xi Chen, Qingsong Pang

Intra-abdominal infection after tumor surgery: tigecycline combined with β-lactam antibiotics versus tigecycline alone

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Xinfeng Cai, Hongxia Yan, Wenjun Zhang, Wei Zhao, Lei Zhang, Xu Wang, Xinjing Wu, Zhiying Hao, Jinlin Guo

Vaginal microbiome community state types and high-risk human papillomaviruses in cervical precancer and cancer in North-central Nigeria

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Jonah Musa, Mamoudou Maiga, Stefan J. Green, Francis A. Magaji, Ali J. Maryam, Mark Okolo, Chuwang J. Nyam, Nanma T. Cosmas, Olugbenga A. Silas, Godwin E. Imade, Yinan Zheng, Brian T. Joyce, Brehima Diakite, Imran Morhason-Bello, Chad J. Achenbach, Atiene S. Sagay, Innocent A.O. Ujah, Robert L. Murphy, Lifang Hou, Supriya Dinesh Mehta

Knockdown of RBM15 inhibits tumor progression and the JAK-STAT signaling pathway in cervical cancer

• Open Access
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Chunnian Zhang, Liqin Gu, Juan Xiao, Feng Jin

Correction: Associations between detectable circulating tumor DNA and tumor glucose uptake measured by 18F-FDG PET/CT in early-stage non-small cell lung cancer

• Open Access
• Correction

Anine Larsen Ottestad, Håkon Johansen, Tarje Onsøien Halvorsen, Hong Yan Dai, Sissel Gyrid Freim Wahl, Elisabeth Fritzke Emdal, Bjørn Henning Grønberg

SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy

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Xiaobin Zheng, Jing Lin, Jiani Xiong, Yanfang Guan, Bin Lan, Yi Li, Xuan Gao, Zhaodong Fei, Lisha Chen, Lizhu Chen, Ling Chen, Gang Chen, Zengqing Guo, Xin Yi, Weiguo Cao, Xinghao Ai, Chengzhi Zhou, Xiaofeng Li, Jun Zhao, Xiangtao Yan, Qitao Yu, Lu Si, Yu Chen, Chuanben Chen

Understanding the contribution of lifestyle in breast cancer risk prediction: a systematic review of models applicable to Europe

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Elly Mertens, Antonio Barrenechea-Pulache, Diana Sagastume, Maria Salve Vasquez, Stefanie Vandevijvere, José L. Peñalvo

Six polymorphisms in the lncRNA H19 gene and the risk of cancer: a systematic review and meta-analysis

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Maoquan Yang, Mingwei Zhang, Qiong Wang, Xiaojing Guo, Peizhen Geng, Jinhua Gu, Wansheng Ji, Li Zhang

Patient-derived organoids for precision oncology: a platform to facilitate clinical decision making

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Swati Chitrangi, Pooja Vaity, Aishwarya Jamdar, Shweta Bhatt

RETRACTED ARTICLE: KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis

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Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-Jin Kim, Jacob E. Till, Jong Hyun Kim, Sara H. Keshavjee, Sandra Ryeom, Sam S. Yoon

Hepatic arterial infusion in combination with systemic chemotherapy in patients with hepatic metastasis from colorectal cancer: a randomized phase II study – (NCT05103020) – study protocol

• Open Access
• Study protocol

Ji Su Kim, Hyunwook Kim, Seo Young Lee, Yoon Dae Han, Kichang Han, Byung Soh Min, Man-Deuk Kim, Jong Yun Won, Seung-Hoon Beom, Sang Joon Shin, Han Sang Kim, Dai Hoon Han, Joong Bae Ahn

Comprehensive analysis of the clinical and biological significances of cholesterol metabolism in lower-grade gliomas

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Rui Tao, Ruoyu Huang, Jingchen Yang, Jiangfei Wang, Kuanyu Wang

Ultrasound-stimulated microbubbles enhancement of fractionated radiation for tumor treatment

• Open Access
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Deepa Sharma, Evan McNabb, Niki Law, Aaron Cumal, Gregory J Czarnota

A novel PEGylated form of granulocyte colony-stimulating factor, mecapegfilgrastim, for peripheral blood stem cell mobilization in patients with hematologic malignancies

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Jingjing Wen, Qiaolin Zhou, Lin Shi, Fang Xu, Yiping Liu, Jing Su, Ya Zhang, Wen Qu, Jing Yue

Pararespiratory and paradigestive lymph node metastases in esophageal squamous cell carcinoma: predicting survival and refining the N staging system

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Dong Tian, Kai-Yuan Jiang, Yu-Shang Yang, Hao-Ji Yan, Rui-Xuan Yu, Heng Huang, Shun-Hai Jian, Hai-Ning Zhou, Hong-Ying Wen, Long-Qi Chen

JMJD6 functions as an oncogene and is associated with poor prognosis in esophageal squamous cell carcinoma

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Honggang Liu, Menglong Jiang, Fenghui Ma, Jiapei Qin, Xin Zhou, Liqun Xu, Xiaolong Yan, Tao Jiang

Correction: Predictive and prognostic markers from endoscopic ultrasound with biopsies during definitive chemoradiation therapy in esophageal squamous cell carcinoma

• Open Access
• Correction

Qingwu Du, Xiaoyue Wu, Kunning Zhang, Fuliang Cao, Gang Zhao, Xiaoying Wei, Zhoubo Guo, Yang Li, Jie Dong, Tian Zhang, Wencheng Zhang, Ping Wang, Xi Chen, Qingsong Pang

Predicting survival for patients with mesothelioma: development of the PLACE prognostic model

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Yuan Zhang, Nan Li, Ran Li, Yumei Gu, Xiaofang Liu, Shu Zhang

Characterization of a novel peptide mined from the Red Sea brine pools and modified to enhance its anticancer activity

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Youssef T. Abdou, Sheri M. Saleeb, Khaled M. A. Abdel-Raouf, Mohamed Allam, Mustafa Adel, Asma Amleh

Impact of COVID-19 control on lung, breast, and colorectal pathological cancer diagnoses. A comparison between the Netherlands, Aotearoa New Zealand, and Northern Ireland

• Open Access
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Helen Mitchell, Jennifer Mclean, Anna T Gavin, Otto Visser, Elinor Millar, Tessa Luff, Damien Bennett

Maintaining quality of life and care for cancer survivors experiencing disaster disruptions: a review of the literature

• Open Access
• Review

Yoshiko Kitamura, Hisao Nakai

Efficacy and safety of PEG-rhG-CSF versus rhG-CSF in preventing chemotherapy-induced-neutropenia in early-stage breast cancer patients

• Open Access
• Research

Yantao Jiang, Ju Zhang, Jianxin Zhong, Hao Liao, Jiayang Zhang, Yaxin Liu, Yuehua Liang, Huiping Li

Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1

• Open Access
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Sewoong Lee, Eunjeong Kang, Unju Lee, Sayeon Cho

The association of serum IL-33/ST2 expression with hepatocellular carcinoma

• Open Access
• Research

Xiaolan Pan, Jinfeng Liu, Meiqin Li, Yihua Liang, Zhimin Liu, Ming Lao, Min Fang

How breast cancer therapies impact body image – real-world data from a prospective cohort study collecting patient-reported outcomes

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Melissa Afshar-Bakshloo, Sarah Albers, Chiara Richter, Ottilia Berninger, Jens-Uwe Blohmer, Robert Roehle, Dorothee Speiser, Maria Margarete Karsten

Preoperative serum bilirubin is an independent prognostic factor for curatively resected esophageal squamous cell carcinoma

• Open Access
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Xiancong Huang, Yang Chen, Huan Yang, Ruting Wang, Zhongjian Chen

Clinical value of circulating tumor cells and hematological parameters in 617 Chinese patients with colorectal cancer: retrospective analysis

• Open Access
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Yuhao He, Xinxin He, Yubo Zhou, Shanshan Luo

A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer

• Open Access
• Research

Ernest Nadal, Mansoor Saleh, Santiago Ponce Aix, Maria Ochoa-de-Olza, Sandip Pravin Patel, Scott Antonia, Yumin Zhao, Ivelina Gueorguieva, Michael Man, Shawn T. Estrem, Jiangang Liu, Emin Avsar, Wen Hong Lin, Karim A. Benhadji, Leena Gandhi, Susan C. Guba, Inmaculada Ales Diaz

Hypofractionated stereotactic radiotherapy (HFSRT) versus single fraction stereotactic radiosurgery (SRS) to the resection cavity of brain metastases after surgical resection (SATURNUS): study protocol for a randomized phase III trial

• Open Access
• Study protocol

Maria Waltenberger, Denise Bernhardt, Christian Diehl, Jens Gempt, Bernhard Meyer, Christoph Straube, Benedikt Wiestler, Jan J. Wilkens, Claus Zimmer, Stephanie E. Combs

Evaluation of the interest to combine a CD4 Th1-inducer cancer vaccine derived from telomerase and atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma: a randomized non-comparative phase II study (TERTIO – PRODIGE 82)

• Open Access
• Study Protocol

Angélique Vienot, Marion Jacquin, Magali Rebucci-Peixoto, Dimitri Pureur, François Ghiringhelli, Eric Assenat, Pascal Hammel, Olivier Rosmorduc, Morgane Stouvenot, Manon Allaire, Mohamed Bouattour, Hélène Regnault, Serge Fratte, Eric Raymond, Emilie Soularue, Stéphanie Husson-Wetzel, Vincent Di Martino, Allison Muller, Anne-Laure Clairet, Christine Fagnoni-Legat, Olivier Adotevi, Aurélia Meurisse, Dewi Vernerey, Christophe Borg

Parallel administration of nanoliposomal irinotecan and levo-leucovorin for pancreatic cancer

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Ryoji Takada, Kenji Ikezawa, Takuo Yamai, Ko Watsuji, Yusuke Seiki, Yasuharu Kawamoto, Takeru Hirao, Sena Higashi, Makiko Urabe, Yugo Kai, Tasuku Nakabori, Hiroyuki Uehara, Michiyo Kotani, Toshinari Yagi, Miho Kimura, Keisuke Nozaki, Mari Takagi, Kazuyoshi Ohkawa

Network Evolution Model-based prediction of tumor mutation burden from radiomic-clinical features in endometrial cancers

• Open Access
• Research

Qing Tan, Qian Wang, Suoqin Jin, Fuling Zhou, Xiufen Zou

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

• Open Access
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Chia-Hung Chien, Chien-Cheng Lai, Jian-Ying Chuang, Jui-Mei Chu, Chan-Chuan Liu, Kwang-Yu Chang

Consensus guidelines for the management of HR-positive HER2/neu negative early breast cancer in India, SAARC region and other LMIC by DELPHI survey method

• Open Access
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Purvish Parikh, Govind Babu, Randeep Singh, Vamshi Krishna, Amit Bhatt, Indu Bansal, Senthil Rajappa, Tarini Prasad Sahoo, Shyam Aggarwal, Ajay Bapna, Ghanshyam Biswas, SP Somashekhar, Jyoti Bajpai, Vashishtha Maniar, Sharad Desai, T Raja, Goura Kishor Rath

Development and validation of prognostic nomogram for T1-3N0M0 non-small cell lung cancer after curative resection

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Weijian Mei, Wang Yao, Zhengbo Song, Wenjie Jiao, Lianxin Zhu, Qinghua Huang, Chaolun An, Jianguang Shi, Guiping Yu, Pingli Sun, Yinbin Zhang, Jianfei Shen, Chunwei Xu, Han Yang, Qian Wang, Zhihua Zhu

TUBA1C is a potential new prognostic biomarker and promotes bladder urothelial carcinoma progression by regulating the cell cycle

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Yi Jiang, Chao Zhu, Haoxuan Huang, Gaomin Huang, Bin Fu, Xiaoqing Xi

Salidroside regulates tumor microenvironment of non-small cell lung cancer via Hsp70/Stub1/Foxp3 pathway in Tregs

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Zexin Wen, Tong Liu, Yanli Zhang, Qiujuan Yue, Hang Meng, Yijie He, Yi Yang, Minghao Li, Jianwen Zheng, Wei Lin

A nomogram for predicting lateral lymph node metastasis in cN0 unifocal papillary thyroid microcarcinoma

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Hui Huang, Siyuan Xu, Song Ni, Xiaolei Wang, Shaoyan Liu

Rational application of EGFR-TKI adjuvant therapy in patients with completely resected stage IB-IIIA EGFR-mutant NSCLC: a systematic review and meta-analysis of 11 randomized controlled trials

• Open Access
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Shu-Ling Zhang, Xiao-Fang Yi, Le-Tian Huang, Li Sun, Jie-Tao Ma, Cheng-Bo Han

A nomogram prediction model for the TP53mut subtype in endometrial cancer based on preoperative noninvasive parameters

• Open Access
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Wei Wang, Xiaoting Li, Yunong Gao, Hong Zheng, Min Gao

A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation

• Open Access
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Hira Javaid, Alessandro Barberis, Olga Chervova, Isar Nassiri, Vitaly Voloshin, Yusuke Sato, Seishi Ogawa, Benjamin Fairfax, Francesca Buffa, Timothy C. Humphrey

Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer

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Mariam Al-Omari, Tareq Al-Omari, Nesreen Batainah, Khaled Al-Qauod, Beata Olejnicka, Sabina Janciauskiene

Detection of Human cytomegalovirus UL55 Gene and IE/E Protein Expression in Colorectal Cancer Patients in Egypt

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May Raouf, Ahmed A. Sabry, Mahinour A. Ragab, Samar El Achy, Amira Amer

Involved site radiation therapy in stage I-III nasopharyngeal carcinoma with limited lymph node burden (ISRT-NPC) or elective region irradiation: a study protocol for a multicenter non-inferiority randomized controlled phase III clinical trial

• Open Access
• Study protocol

Yang Liu, Yaqian Han, Feng Liu, Desheng Hu, Zhijian Chen, Peiguo Wang, Jingao Li, Jiyong Qin, Feng Jin, Yexiong Li, Jingbo Wang, Junlin Yi

A novel metabolic subtype with S100A7 high expression represents poor prognosis and immuno-suppressive tumor microenvironment in bladder cancer

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Yun Cai, Yifei Cheng, Ziyu Wang, Lu Li, Zhengtao Qian, Wei Xia, Weiwei Yu

Randomised phase II trial of trifluridine/tipiracil (FTD/TPI) plus ramucirumab (RAM) versus trifluridine/tipiracil for previously treated patients with advanced gastric or esophagogastric junction adenocarcinoma (RETRIEVE study, WJOG15822G)

• Open Access
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Naoki Takahashi, Hiroki Hara, Kengo Nagashima, Kenro Hirata, Toshiki Masuishi, Toshihiko Matsumoto, Hisato Kawakami, Kentaro Yamazaki, Shuichi Hironaka, Narikazu Boku, Kei Muro

Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

• Open Access
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Jinna Li, Qing Guo, Rui Xing

Perioperative or adjuvant mFOLFIRINOX for resectable pancreatic cancer (PREOPANC-3): study protocol for a multicenter randomized controlled trial

• Open Access
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J. L. van Dam, E. M. M. Verkolf, E. N. Dekker, B. A. Bonsing, S. O. Bratlie, L. A. A. Brosens, O. R. Busch, L. M. J. W. van Driel, C. H. J. van Eijck, S. Feshtali, P. Ghorbani, D. J. A. de Groot, J. W. B. de Groot, B. C. M. Haberkorn, I. H. de Hingh, B. van der Holt, T. M. Karsten, M. B. van der Kolk, K. J. Labori, M. S. L. Liem, O. J. L. Loosveld, I. Q. Molenaar, M. B. Polée, H. C. van Santvoort, J. de Vos – Geelen, M. L. Wumkes, G. van Tienhoven, M. Y. V. Homs, M. G. Besselink, J. W. Wilmink, B. Groot Koerkamp

Sintilimab plus nab-paclitaxel as second-line treatment for advanced biliary tract cancer: study protocol for an investigator-initiated phase 2 trial (NapaSinti trial)

• Open Access
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Nan Zhou, Xiaofen Li, Yu Yang, Sirui Tan, Shunyu Zhang, Qiyue Huang, Hongfeng Gou

Predictive power of PEN-3 cultural model in cervical cancer screening among women: a cross- sectional study in South of Iran

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Sara Dadipoor, Azin Alavi, Zainab Kader, Shokrollah Mohseni, Hadi Eshaghi Sani Kakhaki, Nahid Shahabi

Cetuximab as first-line treatment for metastatic colorectal cancer (mCRC): a model-based economic evaluation in Indonesia setting

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Septiara Putri, Siti Rizny F. Saldi, Levina Chandra Khoe, Ery Setiawan, Amila Megraini, Benjarin Santatiwongchai, Ryan R. Nugraha, Vetty Y. Permanasari, Mardiati Nadjib, Sudigdo Sastroasmoro, Armansyah Armansyah

BYL719 reverses gefitinib-resistance induced by PI3K/AKT activation in non-small cell lung cancer cells

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Yaya Yu, Zhenzhen Xiao, Chenjing Lei, Changju Ma, Lina Ding, Qing Tang, Yihan He, Yadong Chen, Xuesong Chang, Yanjuan Zhu, Haibo Zhang

Systematic analysis of histone acetylation regulators across human cancers

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Congkuan Song, Xinfei Liu, Weichen Lin, Kai Lai, Shize Pan, Zilong Lu, Donghang Li, Ning Li, Qing Geng

Total neoadjuvant therapy with short-course radiotherapy Versus long-course neoadjuvant chemoradiotherapy in Locally Advanced Rectal cancer, Korean trial (TV-LARK trial): study protocol of a multicentre randomized controlled trial

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• Study Protocol

Min Jung Kim, Dae Won Lee, Hyun-Cheol Kang, Ji Won Park, Seung-Bum Ryoo, Sae-Won Han, Kyung Su Kim, Eui Kyu Chie, Jae Hwan Oh, Woon Kyung Jeong, Byoung Hyuck Kim, Eun Mi Nam, Seung-Yong Jeong

Prognostic and immune infiltrative biomarkers of CENPO in pan–cancer and its relationship with lung adenocarcinoma cell proliferation and metastasis

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Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv, Wanbo Shen, Hui Li, Linghan Tian, Zongling Fan, Yanling Li, Yan wang, Feng Li, Yan Chen

Impact of web application support versus standard management on adherence with adjuvant hormone therapy in patients treated for breast cancer: the WEBAPPAC study

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François Gernier, Jean-Michel Grellard, Charlotte Dupont, Hervé Castel, Marie Fernette, François Lahaye, Rose-Marie Charles, Tiphaine Leroux, Céline Ory, Audrey Faveyrial, Adeline Morel, George Emile, Christelle Levy, Carine Segura, Djelila Allouache, Alison Johnson, Julien Geffrelot, Katharina Gunzer, Anaïs Lelaidier, Gilles Girault, Coraline Dubot-poitelon, Chankannira San, Justine Lequesne, Bénédicte Clarisse

ExPert ConsEnsus on the management of Advanced clear-cell RenaL celL carcinoma: INDIAn Perspective (PEARL-INDIA)

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Tarini Prasad Sahoo, Chirag Desai, Shyam Agarwal, Amit Rauthan, Boman Dhabhar, Ghanshyam Biswas, Sandeep Batra, Rajat Saha, Arun Philip, Vijay Agarwal, Palanki Satya Dattatreya, PN Mohapatra, Chetan Deshmukh, Sagar Bhagat, Saiprasad Patil, Hanmant Barkate

Extended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer

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Anna Öfverholm, Therese Törngren, Anna Rosén, Brita Arver, Zakaria Einbeigi, Karin Haraldsson, Anne Kinhult Ståhlbom, Ekaterina Kuchinskaya, Annika Lindblom, Beatrice Melin, Ylva Paulsson-Karlsson, Marie Stenmark-Askmalm, Emma Tham, Anna von Wachenfeldt, Anders Kvist, Åke Borg, Hans Ehrencrona

Overall survival of patients with thyroid cancer in Martinique (2008–2018)

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Lyvio Lin, Thierry Almont, Murielle Beaubrun, Jonathan Macni, Aimée Pierre-Louis, Audrey Zabulon, Ciprian Draganescu, Lucien Lin, Nadia Sabbah, Moustapha Drame, Jacqueline Veronique-Baudin, Clarisse Joachim

Correction: Thoracic radiotherapy plus Durvalumab in elderly and/or frail NSCLC stage III patients unfit for chemotherapy - employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy: study protocol of the TRADE-hypo trial

• Open Access
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Farastuk Bozorgmehr, Inn Chung, Petros Christopoulos, Johannes Krisam, Marc A. Schneider, Lena Brückner, Daniel Wilhelm Mueller, Michael Thomas, Stefan Rieken

Mechanism of prognostic marker SPOCK3 affecting malignant progression of prostate cancer and construction of prognostic model

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Jiawen Luo, Cong Lai, Xiaoting Xu, Juanyi Shi, Jintao Hu, Kaixuan Guo, Yelisudan Mulati, Yunfei Xiao, Degeng Kong, Cheng Liu, Kewei Xu

Radiotherapy in bone sarcoma: the quest for better treatment option

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Marie-Anaïs Locquet, Mehdi Brahmi, Jean-Yves Blay, Aurélie Dutour

AGR2 and FOXA1 as prognostic markers in ER-positive breast cancer

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Meng Zhou, Xing-li Gan, Yue-xiang Ren, Qian-xin Chen, Yuan-zhong Yang, Zi-jin Weng, Xiao-fang Zhang, Jie-xia Guan, Lu-ying Tang, Ze-fang Ren

Acceptability of prehabilitation for cancer surgery: a multi-perspective qualitative investigation of patient and ‘clinician’ experiences

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Rachael Powell, Amy Davies, Kirsty Rowlinson-Groves, David P French, John Moore, Zoe Merchant

A real-world disproportionality analysis of Rucaparib: Post-marketing Pharmacovigilance Data

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Qilin Zhang, Yiling Ding, Yamin Shu, Jing Chen

First-line induction chemotherapy with high-dose methotrexate versus teniposide in patients with newly diagnosed primary central nervous system lymphoma: a retrospective, multicenter cohort study

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Kaili Zhong, Yanyan Shi, Yuhuan Gao, Huilai Zhang, Mingzhi Zhang, Qiaohua Zhang, Xinan Cen, Mei Xue, Yan Qin, Yu Zhao, Liling Zhang, Rong Liang, Ningju Wang, Yan Xie, Yu Yang, Aichun Liu, Huizheng Bao, Jingwen Wang, Baoping Cao, Wei Zhang, Weijing Zhang

Prehabilitation in the lung cancer pathway: a scoping review

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Kelly Wade-Mcbane, Alex King, Catherine Urch, Julian Jeyasingh-Jacob, Andrew Milne, Clair Le Boutillier

Treatment with anticancer drugs for advanced pancreatic cancer: a systematic review

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Josefina Salazar, Javier Bracchiglione, Olga Savall-Esteve, Alba Antequera, David Bottaro-Parra, Marta Gutiérrez-Valencia, Susana Martínez-Peralta, Carles Pericay, Ariadna Tibau, Xavier Bonfill, Roberto Acosta-Dighero, Ariadna Auladell-Rispau, Yahveth Cantero-Fortiz, Edgar Hernandez, Juan Irassar, Adriana-G Meade, Pamela Meinardi, Angela Merchán-Galvis, Nicolas Meza, María Jesús Quintana, Carolina Requeijo, Gerardo Rodriguez-Grijalva, Karla Salas-Gama, Marilina Santero, Olga Savall-Esteve, Anna Selva, Ivan Solà, Gerard Urrútia

CRISPR-Cas9 identifies growth-related subtypes of glioblastoma with therapeutical significance through cell line knockdown

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Nannan Zhao, Siyuan Weng, Zaoqu Liu, Hui Xu, Yuqin Ren, Chunguang Guo, Long Liu, Zhenyu Zhang, Yuchen Ji, Xinwei Han

Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells

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Erika Naakka, Wafa Wahbi, Riia Tiikkaja, Krista Juurikka, Toni Sandvik, Petri Koivunen, Timo Autio, Jukka Tikanto, Janne Väisänen, Hannu Tuominen, Anne Talvensaari-Mattila, Ahmed Al-Samadi, Rabah Soliymani, Pirjo Åström, Maija Risteli, Tuula Salo

Preoperative sarcopenia combined with prognostic nutritional index predicts long-term prognosis of radical gastrectomy with advanced gastric cancer: a comprehensive analysis of two-center study

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Yubo Han, Ju Wu, Rui Ji, Hao Tan, Simiao Tian, Jiajun Yin, Jian Xu, Xi Chen, Wenfei Liu, Hongzhang Cui

Necroptosis-related LncRNAs in skin cutaneous melanoma: evaluating prognosis, predicting immunity, and guiding therapy

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Jianlan Liu, Binlin Luo, Pengpeng Zhang, Keyu Jiang, Zuoqiong Hou, Xiaojian Cao, Jian Tang

Efficacy and safety of fluzoparib combined with anlotinib in extensive stage small cell lung cancer after first-line platinum-based chemotherapy: a multi-center, single-arm prospective phase II clinical study (STAMP study)

• Open Access
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Deyu Li, Zhangzhou Huang, Jiangming Zhong, Li Lin, Guifeng Zhang, Wu Zhuang, Zhenhua Liu

Defining aggressive prostate cancer: a geospatial perspective

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Daniel Wiese, Tesla D. DuBois, Kristen A. Sorice, Carolyn Y. Fang, Camille Ragin, Mary B. Daly, Adam C. Reese, Kevin A. Henry, Shannon M. Lynch

Serum lncRNA THRIL predicts benign and malignant pulmonary nodules and promotes the progression of pulmonary malignancies

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Xinyu Chen, Xianji Zhu, Wenjun Yan, Luan Wang, Dongming Xue, Shouying Zhu, Jiajun Pan, Yufeng Li, Qixiang Zhao, Dong Han

Addressing cancer care in low- to middle-income countries: a call for sustainable innovations and impactful research

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• Editorial

D. Cristina Stefan, Shenglan Tang

Effect of cumulative radiation exposure from Coronary catheterization on lung cancer mortality

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Jin Liu, Shiqun Chen, Yang Zhou, Xueyan Zheng, Ruilin Meng, Ning Tan, Yong Liu

Alcohol consumption and cancer incidence in women: interaction with smoking, body mass index and menopausal hormone therapy

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Sarah Floud, Carol Hermon, Rachel F Simpson, Gillian K Reeves

RETRACTED ARTICLE: Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma

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Yu Zhang, Tianyi Zhang, Yingdong Zhao, Hongdi Wu, Qiang Zhen, Suwei Zhu, Shaoshuai Hou

3D-based strain analysis and cardiotoxicity detection in cancer patients received chemotherapy

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Muhammad Azzam, Mohammad Wasef, Hani Khalaf, Ahmed Al-Habbaa

Changing patterns of nasopharyngeal carcinoma incidence in Hong Kong: a 30-year analysis and future projections

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Xiaoyan Wang, Haifeng Sun, Linchang Li, Zhenhai Gan, Xiaoming Wu, Jianqiang Du

Targeting sphingolipid metabolism with the sphingosine kinase inhibitor SKI-II overcomes hypoxia-induced chemotherapy resistance in glioblastoma cells: effects on cell death, self-renewal, and invasion

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Nadia Sousa, Carsten Geiß, Laura Bindila, Ingo Lieberwirth, Ella Kim, Anne Régnier-Vigouroux

An artificial intelligence-based ecological index for prognostic evaluation of colorectal cancer

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Qicong Chen, Ming Cai, Xinjuan Fan, Wenbin Liu, Gang Fang, Su Yao, Yao Xu, Qian Li, Yingnan Zhao, Ke Zhao, Zaiyi Liu, Zhihua Chen

Efficacy and safety of venetoclax combined with hypomethylating agents for relapse of acute myeloid leukemia and myelodysplastic syndrome post allogeneic hematopoietic stem cell transplantation: a systematic review and meta-analysis

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Yufeng Du, Chunhong Li, Zhijia Zhao, Yikun Liu, Chengtao Zhang, Jinsong Yan

Anaplastic lymphoma kinase overexpression enhances aggressive phenotypic characteristics of endometrial carcinoma

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Ako Yokoi, Yusaku Nakamura, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Mayu Nakagawa, Yu Ishibashi, Takashi Ito, Kensuke Ohhigata, Youhei Harada, Naomi Fukagawa, Makoto Saegusa

Receipt of mastectomy and adjuvant radiotherapy following breast conserving surgery (BCS) in New Zealand women with BCS-eligible breast cancer, 2010–2015: an observational study focusing on ethnic differences

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Karen Bartholomew, Mazin Ghafel, Sandar Tin Tin, Phyu S Aye, J Mark Elwood, Claire Hardie, Nina Scott, Jacquie Kidd, Reena Ramsaroop, Ian Campbell

Age-adjusted high-dose chemotherapy followed by autologous stem cell transplantation or conventional chemotherapy with R-MP as first-line treatment in elderly primary CNS lymphoma patients – the randomized phase III PRIMA-CNS trial

• Open Access
• Study Protocol

Lisa K Isbell, Roswitha Uibeleisen, Alexander Friedl, Elvira Burger, Tatja Dopatka, Florian Scherer, Andras Orban, Eliza Lauer, Natalie Malenica, Inna Semenova, Annika Vreden, Elke Valk, Julia Wendler, Simone Neumaier, Heidi Fricker, Abed Al Hadi El Rabih, Cora Gloggengießer, Daniela Hilbig, Sabine Bleul, Joachim Weis, Dennis Gmehlin, Matthias Backenstrass, Sebastian Wirtz, Gabriele Ihorst, Jürgen Finke, Gerald Illerhaus, Elisabeth Schorb

Correction: Patient-derived organoids for precision oncology: a platform to facilitate clinical decision making

• Open Access
• Correction

Swati Chitrangi, Pooja Vaity, Aishwarya Jamdar, Shweta Bhatt

Correction: Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells

• Open Access
• Correction

Christian Koch, Nina Charlotte Fischer, Malte Puchert, Jürgen Engele

The efficacy of adjuvant chemotherapy for older adults with stage II/III gastric cancer: a retrospective cohort study

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Yu-Hsuan Shih, Hsin-Chen Lin, Po-Wei Liao, Cheng-Wei Chou, Cheng-Hsien Lin, Chiann-Yi Hsu, Chieh-Lin Jerry Teng, Feng-Hsu Wu, Shao-Ciao Luo, Shao-Hsuan Kao

Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol

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• Study protocol

Daan Andel, Marnix G. E. H. Lam, Joep de Bruijne, Maarten L. J. Smits, Arthur J. A. T. Braat, Adriaan Moelker, Erik Vegt, Simeon J. S. Ruiter, Walter Noordzij, Gianluca Grazi, Giulio E. Vallati, Roel J. Bennink, Otto M. van Delden, Onno W. Kranenburg, Jan N. M. Ijzermans, Maarten W. Nijkamp, Joris I. Erdmann, Rosa Sciuto, Jeroen Hagendoorn, Inne H. M. Borel Rinkes

Estimating cancer incidence in Uganda: a feasibility study for periodic cancer surveillance research in resource limited settings

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Annet Nakaganda, Angela Spencer, Jackson Orem, Collins Mpamani, Henry Wabinga, Sarah Nambooze, Gertrude N. Kiwanuka, Raymond Atwine, Isla Gemmell, Andrew Jones, Arpana Verma

Tumor microenvironment characterization in colorectal cancer to identify prognostic and immunotherapy genes signature

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Xian-wen Guo, Rong-e Lei, Qing-nan Zhou, Guo Zhang, Bang-li Hu, Yun-xiao Liang

Pain and its interference with daily living in relation to cancer: a comparative population-based study of 16,053 cancer survivors and 106,345 people without cancer

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• Research article

Grace Joshy, Saman Khalatbari-Soltani, Kay Soga, Phyllis Butow, Rebekah Laidsaar-Powell, Bogda Koczwara, Nicole M. Rankin, Sinan Brown, Marianne Weber, Carolyn Mazariego, Paul Grogan, John Stubbs, Stefan Thottunkal, Karen Canfell, Fiona M. Blyth, Emily Banks

Inhibiting PRMT5 induces DNA damage and increases anti-proliferative activity of Niraparib, a PARP inhibitor, in models of breast and ovarian cancer

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Shane O’Brien, Michael Butticello, Christine Thompson, Boris Wilson, Anastasia Wyce, Vivek Mahajan, Ryan Kruger, Helai Mohammad, Andy Fedoriw

A novel super-enhancer-related gene signature predicts prognosis and immune microenvironment for breast cancer

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Qing Wu, Xuan Tao, Yang Luo, Shiyao Zheng, Nan Lin, Xianhe Xie

Neo-train: study protocol and feasibility results for a two-arm randomized controlled trial investigating the effect of supervised exercise during neoadjuvant chemotherapy on tumour response in patients with breast cancer

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• Study Protocol

Eva Kjeldsted, Gunn Ammitzbøll, Lars Bo Jørgensen, Alexey Lodin, Rasmus Dahlin Bojesen, Silvia Gonzalez Ceballos, Susanne Rosthøj, Anne-Vibeke Lænkholm, Søren T. Skou, Sandy Jack, Julie Gehl, Susanne Oksbjerg Dalton

Skeletal muscle index is associated with long term outcomes after lobectomy for non-small cell lung cancer

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Yeshwanth Vedire, Lindsay Nitsche, Madeline Tiadjeri, Victor McCutcheon, Jack Hall, Joseph Barbi, Sai Yendamuri, Andrew D. Ray

NEXUS trial: a multicenter phase II clinical study evaluating the efficacy and safety of the perioperative use of encorafenib, binimetinib, and cetuximab in patients with previously untreated surgically resectable BRAF V600E mutant colorectal oligometastases

• Open Access
• Study Protocol

Shin Kobayashi, Hideaki Bando, Akinobu Taketomi, Takeshi Takamoto, Eiji Shinozaki, Manabu Shiozawa, Hiroki Hara, Kentaro Yamazaki, Koji Komori, Nobuhisa Matsuhashi, Takeshi Kato, Yoshinori Kagawa, Mitsuru Yokota, Eiji Oki, Keigo Komine, Shinichiro Takahashi, Masashi Wakabayashi, Takayuki Yoshino

Protocol of the RACB study: a multicenter, single-arm, prospective study to evaluate the efficacy of resection of initially unresectable hepatocellular carcinoma with atezolizumab combined with bevacizumab

• Open Access
• Study Protocol

Masayuki Okuno, Takamichi Ishii, Akihiko Ichida, Akihiko Soyama, Nobuyuki Takemura, Seiko Hirono, Susumu Eguchi, Kiyoshi Hasegawa, Yasuharu Sasaki, Kohei Uemura, Norihiro Kokudo, Etsuro Hatano

Randomized phase II trial of MRI-guided salvage radiotherapy for prostate cancer in 4 weeks versus 2 weeks (SHORTER)

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• Study Protocol

Ariel E. Marciscano, Sydney Wolfe, Xi Kathy Zhou, Christopher E. Barbieri, Silvia C. Formenti, Jim C. Hu, Ana M. Molina, David M. Nanus, Jones T. Nauseef, Douglas S. Scherr, Cora N. Sternberg, Scott T. Tagawa, Himanshu Nagar

Association of meat consumption with the risk of gastrointestinal cancers: a systematic review and meta-analysis

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Yan Di, Lei Ding, Luying Gao, Hongyan Huang

TP53 mutation prevalence in normal airway epithelium as a biomarker for lung cancer risk

• Open Access
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Daniel J. Craig, Erin L. Crawford, Heidi Chen, Eric L. Grogan, Steven A. Deppen, Thomas Morrison, Sanja L. Antic, Pierre P. Massion, James C. Willey

Comparing biweekly single-dose actinomycin D with multiday methotrexate therapy for low-risk gestational trophoblastic neoplasia (FIGO Score 0–4): study protocol for a prospective, multicentre, randomized trial

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• Study protocol

Fang Jiang, Ming-yi Mao, Yang Xiang, Xin Lu, Chong-li Guan, Lan-zhou Jiao, Xi-Run Wan, Feng-Zhi Feng, Tong Ren, Jun-Jun Yang, Jun Zhao

Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study

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Xin Min, Zheng Zhang, Yanwei Chen, Shuangshuang Zhao, Jingwen Ge, Huajiao Zhao, Yun Cai, Hui Chen, Jun Shao, Yanfei Jing, Baoding Chen

Comparison of clinical outcomes among cancer patients treated in and out of clinical trials

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Jose A. Carreno Duenas, Natalia Sanchez P., Carlos E. Bonilla

Predictive value of prognostic nutritional index (PNI) in recurrent or unresectable hepatocellular carcinoma received anti-PD1 therapy

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Xindan Kang, Jing Wang, Xue Kang, Li Bai

Study protocol for a multicenter randomised controlled trial on the (cost)effectiveness of biopsy combined with same-session MR-guided LITT versus biopsy alone in patients with primary irresectable glioblastoma (EMITT trial)

• Open Access
• Study Protocol

Céline L.G. Neutel, Ilaria Viozzi, Christiaan G. Overduin, Anne Rijpma, Janneke P.C. Grutters, Gerjon Hannink, Pieter van Eijsden, Pierre A. Robe, Maroeska M. Rovers, Mark ter Laan

Exosomal ACADM sensitizes gemcitabine-resistance through modulating fatty acid metabolism and ferroptosis in pancreatic cancer

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Yuhan Yang, Haitao Gu, Kundong Zhang, Zengya Guo, Xiaofeng Wang, Qingyun Wei, Ling Weng, Xuan Han, Yan Lv, Meng Cao, Peng Cao, Chen Huang, Zhengjun Qiu

A neoadjuvant therapy compatible prognostic staging for resected pancreatic ductal adenocarcinoma

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Lingyu Zhu, Shuo Shen, Huan Wang, Guoxiao Zhang, Xiaoyi Yin, Xiaohan Shi, Suizhi Gao, Jiawei Han, Yiwei Ren, Jian Wang, Hui Jiang, Shiwei Guo, Gang Jin

Network meta-analysis of first-line immune checkpoint inhibitor therapy in advanced non-squamous non-small cell lung cancer patients with PD-L1 expression ≥ 50%

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Wei Chen, Jiayi Chen, Lin Zhang, Sheng Cheng, Junxian Yu

Neoadjuvant immunotherapy and chemotherapy regimens for the treatment of high-risk, early-stage triple-negative breast cancer: a systematic review and network meta-analysis

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Javier Cortes, Amin Haiderali, Min Huang, Wilbur Pan, Peter Schmid, Katherine G. Akers, Julie E. Park, Andrew M. Frederickson, Peter A. Fasching, Joyce O’Shaughnessy

Pan-cancer analysis identifies SPEN mutation as a predictive biomarker with the efficacy of immunotherapy

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Ya-Dong Li, Hao Huang, Zheng-Ju Ren, Ye Yuan, Hao Wu, Chuan Liu

Prevalence of subclinical lung cancer detected at autopsy: a systematic review

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Asha Bonney, Kayo Togawa, Michelle Ng, Michael Christie, Kwun M Fong, Henry Marshall, Katharine See, Cameron Patrick, Daniel Steinfort, Renee Manser

Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis

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Chao Zhang, Jun Wang, Haixiao Wu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Artem V. Bukharov, Andrey D. Kaprin, Xu Guo, Zheng Liu

Propensity score-matched analysis comparing hippocampus-avoidance whole-brain radiotherapy plus simultaneous integrated boost with hippocampus‑avoidance whole-brain radiotherapy alone for multiple brain metastases-a retrospective study in multiple institutions

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Xiaoliang Wang, Jinping Chen, Zhanquan Lei, Haihong Chen, Yufang Zhang, Gang Liu, Shaomin Li, Zhenhua Zheng, Hui Wang

Interaction analysis of high-risk pathological features on adjuvant chemotherapy survival benefit in stage II colon cancer patients: a multi-center, retrospective study

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Kexuan Li, Fuqiang Zhao, Yuchen Guo, Qingbin Wu, Shuangling Luo, Junling Zhang, Heli Li, Shidong Hu, Bin Wu, Guole Lin, Huizhong Qiu, Beizhan Niu, Xiyu Sun, Lai Xu, Junyang Lu, Xiaohui Du, Zheng Wang, Xin Wang, Liang Kang, Ziqiang Wang, Quan Wang, Qian Liu, Yi Xiao

Assessing cancer in people with profound and multiple disabilities

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Daniel Satgé, Motoi Nishi, Brigitte Trétarre

Kappa statistic considerations in evaluating inter-rater reliability between two raters: which, when and context matters

• Open Access
• Matters Arising

Ming Li, Qian Gao, Tianfei Yu

Correlation of toxicities and efficacies of pemetrexed with clinical factors and single-nucleotide polymorphisms: a prospective observational study

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Yuichiro Takeda, Go Naka, Yuki Katsuya, Konomi Kobayashi, Manabu Suzuki, Masao Hashimoto, Satoshi Hirano, Yukari Uemura

Clinical perspectives and outcomes of the giant breast phyllodes tumor and sarcoma: a real-world retrospective study

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Naiquan Liu, Ye Kang, Ningxin Qu, Chenhui Kong, Ye Han

Identification of novel tumor-associated antigens and evaluation of a panel of autoantibodies in detecting oral cancer

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Weihong Xie, Guiying Sun, Junfen Xia, Huili Chen, Chen Wang, Juan Lin, Peng Wang

The antitumor effect of oncolytic respiratory syncytial virus via the tumor necrosis factor-alpha induction and ROS-bax-mediated mechanisms

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Mehdi Samadi, Talat Mokhtari-Azad, Ahmad Nejati, Zahra Norooz-Babaei, Abbas Rahimi Foroushani, Mohammad Reza Haghshenas, Fatemeh Adjaminejad, Hedieh Zargaran, Vahid Salimi, Amir Ghaemi

Cuproptosis related gene PDHB is identified as a biomarker inversely associated with the progression of clear cell renal cell carcinoma

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Hu Wang, Zhan Yang, Xingyu He, Fengran Guo, Hao Sun, Sen Xu, Chao Xu, Zhu Wang, Hongzhuang Wen, Zhihai Teng, Yaxuan Wang, Zhenwei Han

CDK4/6 inhibitors, PI3K/mTOR inhibitors, and HDAC inhibitors as second-line treatments for hormone receptor-positive, HER2-negative advanced breast cancer: a network meta-analysis

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Danyang Ji, Yang Luo, Jiayu Wang, Shanshan Chen, Bo Lan, Fei Ma, Binghe Xu, Ying Fan

A co-formulation of interferons alpha2b and gamma distinctively targets cell cycle in the glioblastoma-derived cell line U-87MG

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Jamilet Miranda, Dania Vázquez-Blomquist, Ricardo Bringas, Jorge Fernandez-de-Cossio, Daniel Palenzuela, Lidia I. Novoa, Iraldo Bello-Rivero

BRCA genes as candidates for colorectal cancer genetic testing panel: systematic review and meta-analysis

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Zhewen Feng, Xiaobao Yang, Mingwei Tian, Na Zeng, Zhigang Bai, Wei Deng, Yanyan Zhao, Jianru Guo, Yingchi Yang, Zhongtao Zhang, Yun Yang

Circ_0021350 plays an oncogene role by regulating miR-1207-3p/PIK3R3 in glioblastoma

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Cheng Tan, Jun Wei, Zhaohui Li, Nan Tian, Zhengming Wang, Guan Wang, Liang Han, Yu Tian

Factors associated with adherence to provider referrals for lung cancer screening with low dose computed tomography before and during COVID-19 pandemic

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Jiang Li, Cheryl D. Stults, Su-Ying Liang, Meghan Martinez

Real-world comparison of pembrolizumab and nivolumab in advanced hepatocellular carcinoma

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Yen-Hao Chen, Ching-Hua Tsai, Yen-Yang Chen, Chih-Chi Wang, Jing-Houng Wang, Chao-Hung Hung, Yuan-Hung Kuo

BCL7B, a SWI/SNF complex subunit, orchestrates cancer immunity and stemness

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Sayaka Higuchi, Yuji Suehiro, Luna Izuhara, Sawako Yoshina, Akira Hirasawa, Shohei Mitani

Baseline serum tumor markers predict the survival of patients with advanced non-small cell lung cancer receiving first-line immunotherapy: a multicenter retrospective study

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Jian Huang, Yi Xiao, Yubin Zhou, Huiyin Deng, Zihao Yuan, Longyan Dong, Jun Lan, Xiane Li, Gaijiao Liu, Hao Hu, Shaohong Huang, Xiongwen Yang

Automated breast volume scanner based Radiomics for non-invasively prediction of lymphovascular invasion status in breast cancer

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Yue Li, Xiaomin Wu, Yueqiong Yan, Ping Zhou

Public and patient involvement: a survey on knowledge, experience and opinions among researchers within a precision oncology European project

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Paola Mosconi, Cinzia Colombo, Pasquale Paletta, Laura Gangeri, Chiara Pellegrini, Elena Garralda, Rosalba Miceli, Cinzia Brunelli, Irene Braña, Jordi Rodon, Guillermo Villacampa, Anna Pedrola, Rodrigo Dienstmann, Bianca Pont, Júlia Lostes, Alejandro Piris, Elena Chavarria, Xenia Villalobos, Berta Colldeforns, Raquel Pérez-López, Paolo Nuciforo, David Tamborero, Janne Lehtiö, Ali Razzak, Maria Pernemalm, Markus Jonsson, Maan Rachid, Jorrit Boekel, Luigi de Petris, Christina Von Gertten, Helena Bäckvall, Maria Von Witting, Xiaobing He, Richard Baird, Thomas Jaki, Duncan Jodrell, Gary Doherty, Simon Pacey, Rebecca Bradley, Ferida Gallagher, Ramona Woitek, Emma Beddowes, Shubha Anand, Katherine Honan, Haiyan Zheng, Pavel Mozgunov, Nikos Demetris, Kate Donoghue, Kenneth Seamon, Lorena Escudero, Melanie Burton, Otso Arponen, Stefan Fröhling, Richard Schlenk, Petra Oberrauch, Anett Molnar, Manuel Störzel, Klaus Maier-Hein, Oliver Sedlaczek, Heinz-Peter Schlemmer, Peter Horak, Marco Nolden, Simon Kreutzfeldt, Michael Schlander, Philipp Schader, Muchadeyi Muchandifung, Jennifer Wessely, Frans Opdam, Regina Beets-Tan, Zuhir Bodalal, Ruud Weijer, Giovanni Apolone, Giovanni Scoazec, Claudio Vernieri, Rita Leporati, Luca Agnelli, Andrea Vingiani, Mikol Antioco, Silvia Damian, Matteo Duca, Filippo De Braud, Andrea Villa, Sara Alfieri, Arnauld Forest, Laura Lauden, Marc Deloger, Yohan Loriot, Emma Pailler, Paul Fitzpatrick, André Freitas, Ciara Dwan, Donna Graham, Hannah Frost, Leanna Goodwin, Alex Bogatu, Oskar Wysocki, Magdalena Wysocka, Sjoerd van Hagen, Bas Leenknegt, Sander Rodenburg, Elena Garcia, Pim van Nierop, Mirko Orsini, Marco Monari, Marco Pacchioni, Emma Mescoli, Enrico Calanchi

Mucinous tubular and spindle cell carcinoma of the kidney: a report of seven cases

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Chunxiang Ling, Ru Tan, Jiamei Li, Jizhen Feng

Comparative efficacy and safety of different combinations of three CDK4/6 inhibitors with endocrine therapies in HR+/HER-2 − metastatic or advanced breast cancer patients: a network meta-analysis

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Yiyuan Liu, Jinyao Wu, Zeqi Ji, Lingzhi Chen, Juan Zou, Jiehua Zheng, Weixun Lin, Jiehui Cai, Yaokun Chen, Daitian Zheng, Yexi Chen, Zhiyang Li

PD-L1 protein expression by Combined Positive Score (CPS) in patients with muscle invasive or advanced urothelial carcinoma: a single institution experience

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Sarah Nasr, Fadi G. Haddad, Joseph Khazen, Joseph Kattan, Viviane Trak-Smayra

MALAT1-regulated gene expression profiling in lung cancer cell lines

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Jungwook Roh, Boseong Kim, Mijung Im, Wonyi Jang, Yeonsoo Chae, JiHoon Kang, BuHyun Youn, Wanyeon Kim

Exploring the prognostic significance of PKCε variants in cervical cancer

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Sameen Zafar, Khushbukhat Khan, Yasmin Badshah, Kanza Shahid, Janeen H. Trembley, Amna Hafeez, Naeem Mahmood Ashraf, Hamid Arslan, Maria Shabbir, Tayyaba Afsar, Ali Almajwal, Suhail Razak

Clinical trials in cancer screening, prevention and early diagnosis (SPED): a systematic mapping review

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Emma L. O’Dowd, Samuel W. D. Merriel, Vinton W. T. Cheng, Sam Khan, Lynne M. Howells, Dipesh P. Gopal, Elizabeth A. Roundhill, Paul M. Brennan, Philip A. J. Crosbie, Richard D. Neal, Karen Brown, Emma J. Crosbie, David R. Baldwin

circFNDC3B promotes esophageal squamous cell carcinoma progression by targeting MYO5A via miR-370-3p/miR-136-5p

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Dan Song, Ziqi Ye, Fangyu Chen, Liangliang Zhan, Xinchen Sun

Occult lymph node metastasis is not a favorable factor for resected NSCLC patients

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Jing-Sheng Cai, Fan Yang, Xun Wang

Cost-effectiveness analysis of pembrolizumab in combination with chemotherapy compared with chemotherapy alone as first-line treatment for patients with advanced biliary tract cancer in China

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Zhiwei Zheng, Ling Fang, Hongfu Cai

Wilms’ tumour gene 1 (WT1) enhances non-small cell lung cancer malignancy and is inhibited by microRNA-498-5p

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Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang, Yixuan Wang, Wang Shen, Lingling Zu, Fanrong Meng, Xuexia Zhou

TET2 inhibits the proliferation and metastasis of lung adenocarcinoma cells via activation of the cGAS-STING signalling pathway

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Gui Cheng, Jun Wu, Mei Ji, Wenwei Hu, Changping Wu, Jingting Jiang

Renin-angiotensin system inhibitors improve the survival of cholangiocarcinoma: a propensity score-matched cohort study

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Xiao-Xu Zhu, Jian-Hui Li, Peng Fang, Xiao-Fei Qu, Li-Jian Liang, Jia-Ming Lai, Xiao-Yu Yin

Effect of asciminib and vitamin K2 on Abelson tyrosine-kinase-inhibitor-resistant chronic myelogenous leukemia cells

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Seiichi Okabe, Akihiko Gotoh

Using RegGAN to generate synthetic CT images from CBCT images acquired with different linear accelerators

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Zhenkai Li, Qingxian Zhang, Haodong Li, Lingke Kong, Huadong Wang, Benzhe Liang, Mingming Chen, Xiaohang Qin, Yong Yin, Zhenjiang Li

Clinical application of real-time PET/CT guided targeted retroperitoneal masses biopsy in diagnosing malignant tumors

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Xiaomin Li, Wanchun Zhang

Regulatory T cell frequency in peripheral blood of women with advanced cervical Cancer including women living with HIV

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Devamani Chetty-Sebastian, Alain G. Assounga

Impact of media compositions and culture systems on the immunophenotypes of patient-derived breast cancer cells

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Seungyeon Ryu, So-Hyun Yoon, Junhyuk Song, Yoonjung Choi, Sangeun Lee, Moonjou Baek, Han-Byoel Lee, Sook Young Jeon, Sangyong Jon, Daeyoup Lee, Hoe Suk Kim, Wonshik Han

The CA125 level postoperative change rule and its prognostic significance in patients with resectable pancreatic cancer

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Xin Luo, Xianchao Lin, Ronggui Lin, Yuanyuan Yang, Congfei Wang, Haizong Fang, Heguang Huang, Fengchun Lu

Ultrasonography characteristics of cystic components in primary salivary gland tumors

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AngAng Ding, Huan Lv, Jinye Cao, Xin Wang, Ping Xiong

Osteoblastic bone reaction in non-small cell lung cancer harboring epidermal growth factor receptor mutation treated with osimertinib

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Kensuke Kanaoka, Hiromitsu Sumikawa, Shunsuke Oyamada, Akihiro Tamiya, Yuji Inagaki, Yoshihiko Taniguchi, Keiko Nakao, Yoshinobu Matsuda, Kyoichi Okishio

Reduced expression of phosphorylated ataxia-telangiectasia mutated gene is related to poor prognosis and gemcitabine chemoresistance in pancreatic cancer

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Jingyu Xun, Hideo Ohtsuka, Katsuya Hirose, Daisuke Douchi, Shun Nakayama, Masaharu Ishida, Takayuki Miura, Kyohei Ariake, Masamichi Mizuma, Kei Nakagawa, Takanori Morikawa, Toru Furukawa, Michiaki Unno

Effects of blended learning training for oncology physicians to advise their patients about complementary and integrative therapies: results from the multicenter cluster-randomized KOKON-KTO trial

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Stefanie M. Helmer, Alizé A. Rogge, Ryan King, Claudia Canella, Daniel Pach, Claudia M. Witt

Systematic analysis of RNASET2 gene as a potential prognostic and immunological biomarker in clear cell renal cell carcinoma

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Yifu Liu, Zhicheng Zhang, Ping Xi, Ru Chen, Xiaofeng Cheng, Ji Liu, Qiqi Zhu, Yechen Nie, Ting Sun, Binbin Gong, Siyuan Wang

Towards patient-led follow-up after curative surgical resection of stage I, II and III colorectal cancer (DISTANCE-trial): a study protocol for a stepped-wedge cluster-randomised trial

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• Study Protocol

Hidde Swartjes, Seyed M. Qaderi, Steven Teerenstra, Jose A. E. Custers, Marloes A. G. Elferink, Bob J. van Wely, Jacobus W. A. Burger, Wilhelmina M. U. van Grevenstein, Peter van Duijvendijk, Emiel G. G. Verdaasdonk, Marnix A. J. de Roos, Veerle M. H. Coupé, Geraldine R. Vink, Cornelis Verhoef, Johannes H. W. de Wilt

The risk of acute kidney injury in colorectal cancer survivors: an english population-based matched cohort study

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Kirsty Andresen, Helena Carreira, Helen Strongman, Helen I. McDonald, Sara Benitez-Majano, Kathryn E. Mansfield, Dorothea Nitsch, Laurie A. Tomlinson, Krishnan Bhaskaran

Analysis of myosin genes in HNSCC and identify MYL1 as a specific poor prognostic biomarker, promotes tumor metastasis and correlates with tumor immune infiltration in HNSCC

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Ce Li, Rui Guan, Wenming Li, Dongmin Wei, Shengda Cao, Fen Chang, Qun Wei, Ran Wei, Long Chen, Chenyang Xu, Kainan Wu, Dapeng Lei

Impact of estrogen receptor expression level on response to neoadjuvant chemotherapy and prognosis in HER2-negative breast cancers

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Hai-long Chen, Feng-bo Huang, Qiang Chen, Yong-chuan Deng

Association between IL-10 gene polymorphisms (− 1082 A/G, -819 T/C, -592 A/C) and hepatocellular carcinoma: a meta-analysis and trial sequential analysis

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Teresa Tan Yen Mei, Htar Htar Aung, Wong Siew Tung, Cho Naing

MicroRNA 29a therapy for CEACAM6-expressing lung adenocarcinoma

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Seung-Myoung Son, Jieun Yun, Dong-Wook Kim, Young-Suk Jung, Sang-Bae Han, Yong Hee Lee, Hye Sook Han, Chang Gok Woo, Ho-Chang Lee, Ok-Jun Lee

Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications

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Linfeng Chen, Qiming Tang, Keying Zhang, Qianyang Huang, Yun Ding, Bo Jin, Szumam Liu, KuoYuan Hwa, C. James Chou, Yani Zhang, Sheeno Thyparambil, Weili Liao, Zhi Han, Richard Mortensen, James Schilling, Zhen Li, Robert Heaton, Lu Tian, Harvey J. Cohen, Karl G. Sylvester, Rebecca C. Arent, Xinyang Zhao, Doff B. McElhinney, Yumei Wu, Wenpei Bai, Xuefeng B. Ling

Impact of CD40 gene polymorphisms on the risk of cervical squamous cell carcinoma: a case-control study

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Manning Zhu, Xiaoying Li, Yanan Feng, Tianshuang Jia, Songxue Li, Liping Gong, Shuang Dong, Xianchao Kong, Litao Sun

Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

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Shan Enfang, Cao Yi-nan, Zhang Yang, Chen Wen, Ren Xurui, Zhu Shanjie, Xi Xueru, Mu Shuai, Ma Mian, Zhi Tongle, Li Xianwen

A real-world study comparing perioperative chemotherapy and EGFR-tyrosine kinase inhibitors for treatment of resected stage III EGFR-mutant adenocarcinoma

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Chieh-Lung Chen, Sing-Ting Wang, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia, Wen-Chien Cheng, Hung-Jen Chen

Radiomic features from multiparametric magnetic resonance imaging predict molecular subgroups of pediatric low-grade gliomas

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Zhen Liu, Xuanke Hong, Linglong Wang, Zeyu Ma, Fangzhan Guan, Weiwei Wang, Yuning Qiu, Xueping Zhang, Wenchao Duan, Minkai Wang, Chen Sun, Yuanshen Zhao, Jingxian Duan, Qiuchang Sun, Lin Liu, Lei Ding, Yuchen Ji, Dongming Yan, Xianzhi Liu, Jingliang Cheng, Zhenyu Zhang, Zhi-Cheng Li, Jing Yan

Seizure control by adding on other anti-seizure medication on seizure during levetiracetam administration in patients with glioma-related epilepsy

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Etsuko Yamamoto Hattori, Yoshiki Arakawa, Yohei Mineharu, Keiko Furukawa, Yukinori Terada, Yukihiro Yamao, Masahiro Tanji, Takayuki Kikuchi, Susumu Miyamoto

Anatomic versus non-anatomic resection for early-stage intrahepatic cholangiocarcinoma: a propensity score matching and stabilized inverse probability of treatment weighting analysis

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Qiao Ke, Lei Wang, Ziguo Lin, Hongzhi Liu, Jianying Lou, Shuguo Zheng, Xinyu Bi, Jianming Wang, Wei Guo, Fuyu Li, Jian Wang, Yamin Zheng, Jingdong Li, Shi Cheng, Weiping Zhou, Jingfeng Liu, Yongyi Zeng

Clinical implications and immune features of CENPN in breast cancer

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Zhengwei Gui, Yao Tian, Tianyao Yu, Shiyang Liu, Chenguang Liu, Lin Zhang

German mammography screening program: program sensitivity between 2010 and 2016 estimated based on German health claims data

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Franziska Heinze, Jonas Czwikla, Miriam Heinig, Ingo Langner, Ulrike Haug

Increased TCP11 gene expression can inhibit the proliferation, migration and promote apoptosis of cervical cancer cells

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Fang Wang, Shuyan Song, Bingxuan Guo, Yangyang Li, Huijuan Wang, Shaowei Fu, Luyue Wang, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao, Zemin Pan

Causal associations between gut microbiota and urological tumors: a two-sample mendelian randomization study

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Wang Mingdong, Gao Xiang, Quan Yongjun, Wang Mingshuai, Ping Hao

The course of health-related quality of life after the diagnosis of childhood cancer: a national cohort study

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Marloes van Gorp, Elin Irestorm, Jos W. R. Twisk, Natasja Dors, Annelies Mavinkurve-Groothuis, Antoinette Y. N. Schouten van Meeteren, Judith de Bont, Esther M. M. van den Bergh, Wietske van de Peppel van der Meer, Laura R. Beek, Femke K. Aarsen, Nienke Streefkerk, Raphaele R. L. van Litsenburg, Martha A. Grootenhuis

Association between pancreatic cancer and diabetes: insights from a retrospective cohort study

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Fakhrddine Amri, Chifaa Belkhayat, Asmae yeznasni, Hajar Koulali, Rachid Jabi, Abdelkrim Zazour, Naima Abda, Mohammed Bouziane, Zahi Ismaili, Ghizlane Kharrasse

Potential of miR-181a-5p and miR-630 as clinical biomarkers in NSCLC

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Julija Simiene, Daiva Dabkeviciene, Diana Stanciute, Rimvile Prokarenkaite, Valerija Jablonskiene, Renatas Askinis, Kamile Normantaite, Saulius Cicenas, Kestutis Suziedelis

Predicting the outcomes of hepatocellular carcinoma downstaging with the use of clinical and radiomics features

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Si-Yuan Wang, Kai Sun, Shuo Jin, Kai-Yu Wang, Nan Jiang, Si-Qiao Shan, Qian Lu, Guo-Yue Lv, Jia-Hong Dong

Integrative analysis of the prognostic value and immune microenvironment of mitophagy-related signature for multiple myeloma

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Yachun Jia, Rui Liu, Luyi Shi, Yuandong Feng, Linlin Zhang, Ni Guo, Aili He, Guangyao Kong

Value of biplane transrectal ultrasonography plus micro-flow imaging in preoperative T staging and rectal cancer diagnosis in combination with CEA/CA199 and MRI

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Qin Xia, Wei Cheng, Jie Bi, An-Ping Ren, Xiao Chen, Tao Li

Alternating electric fields can improve chemotherapy treatment efficacy in blood cancer cell U937 (non-adherent cells)

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Elham Homami, Bahram Goliaei, Seyed Peyman Shariatpanahi, Zahra Habibi-Kelishomi

An exploratory study of cell stiffness as a mechanical label-free biomarker across multiple musculoskeletal sarcoma cells

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Cyril Daniel, Frank Traub, Saskia Sachsenmaier, Rosa Riester, Moritz Mederake, Christian Konrads, Marina Danalache

Developing an evaluation indicators of health literacy for cervical cancer among Chinese women: a modified Delphi method study

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Chanchan He, Chenyang Pei, Jing Ma

Establishment of a new prognostic risk model of GNG7 pathway-related molecules in clear cell renal cell carcinoma based on immunomodulators

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Jun Zheng, Weili Zhang, Junyong Zhang

Radiotherapy versus low-dose tamoxifen following breast-conserving surgery for low-risk and estrogen receptor-positive breast ductal carcinoma in situ: an international open-label randomized non-inferiority trial (TBCC-ARO DCIS Trial)

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• Study Protocol

Sung-Hsin Kuo, Ling-Ming Tseng, Shou-Tung Chen, Yasuaki Sagara, Yuan-Ching Chang, Hsien-Tang Yeh, Yao-Lung Kuo, Chih-Chiang Hung, Tzu-Pin Lu, Yi-Hsuan Lee, Masakazu Toi, Chiun-Sheng Huang

Acute and early-onset cardiotoxicity in children and adolescents with cancer: a systematic review

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Theodorus W. Kouwenberg, Elvira C. van Dalen, Elizabeth A. M. Feijen, Stejara A. Netea, Melissa Bolier, Martijn G. Slieker, Firdaus A. A. Mohamed Hoesein, Leontien C. M. Kremer, Heynric B. Grotenhuis, Annelies M. C. Mavinkurve-Groothuis

Impact of the COVID-19 pandemic on women living with and beyond breast cancer: a qualitative study of women’s experiences and how they varied by social determinants of health

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Charlotte Myers, Catherine Waldron, Kathleen Bennett, Caitriona Cahir

Exploratory study of an anti-PD-L1/TGF-β antibody, TQB2858, in patients with refractory or recurrent osteosarcoma and alveolar soft part sarcoma: a report from Chinese sarcoma study group (TQB2858-Ib-02)

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Lu Xie, Xin Liang, Jie Xu, Xin Sun, Kuisheng Liu, Kunkun Sun, Yuan Li, Xiaodong Tang, Xianan Li, Xing Zhan, Xiaohui Niu, Wei Guo

Genetic analysis of oligo-recurrence breast cancer: correlation with clinical outcomes

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Kuikui Jiang, Danyang Zhou, Fei Xu, Wen Xia, Qiufan Zheng, Qianyi Lu, Rongzhen Luo, Ruoxi Hong, Shusen Wang

Excellent survival in relapsed stage I testicular cancer

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Philip Speicher, Christian D. Fankhauser, Anja Lorch, Davide Ardizzone, Simon Helnwein, Dennis Hoch, Thomas Hermanns, Jörg Beyer, Dilara Akhoundova

The prognostic significance of histologic variant on survival outcomes in patients with metastatic urothelial carcinoma receiving immune checkpoint inhibitor therapy

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Tsung-Han Tsai, Po-Jung Su, Shih-Yu Huang, Ming-Chun Kuo, Chang-Ting Lin, Chia-Che Wu, Hao-Lun Luo, Chien-Hsu Chen, Chih-Chi Chou, Ting-Ting Liu, Chun-Chieh Huang, Kai-Lung Tsai, Yu-Li Su

Development and validation of a risk model with variables related to non-small cell lung cancer in patients with pulmonary nodules: a retrospective study

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Zufang Liao, Rongjiong Zheng, Ni Li, Guofeng Shao

Improved clinical outcomes in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus atezolizumab and bevacizumab: a bicentric retrospective study

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Fei Cao, Changsheng Shi, Guofu Zhang, Jun Luo, Jiaping Zheng, Weiyuan Hao

Associations between telomere attrition, genetic variants in telomere maintenance genes, and non-small cell lung cancer risk in the Jammu and Kashmir population of North India

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Gh. Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q. Sadida, Sara K. Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A. Macha, Ammira S. Alshabeeb Akil, Ajaz A. Bhat, Rakesh Kumar

Surveillance and treatment of primary hepatocellular carcinoma (aka. STOP HCC): protocol for a prospective cohort study of high-risk patients for HCC using GALAD-score

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• Study protocol

Thai Ngoc Truong, Trang Ngoc Doan Pham, Long Bao Hoang, Van Thi Nguyen, Hang Viet Dao, Diem Vu Bich Dao, Saleh Alessy, Hien Ba Pham, Thuy Thi Thu Pham, Linh Duc Duy Nguyen, Khue Nguyen, Faisal Abaalkhail, Mohammed Manal, Mohammad Mawardi, May AlZahrani, Khalid Alswat, Hamdan Alghamdi, Faisal M. Sanai, Mohammed Amir Siddiqui, Nam Hai Nguyen, Dhananjay Vaidya, Hai Thanh Phan, Philip J. Johnson, Saleh A. Alqahtani, Doan Y Dao

Time trend of pancreatic cancer mortality in the Western Pacific Region: age-period-cohort analysis from 1990 to 2019 and forecasting for 2044

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Wenkai Jiang, Caifei Xiang, Yan Du, Xiao Li, Xin Li, Wence Zhou

Treatment sequences and prognostic/predictive factors in metastatic pancreatic ductal adenocarcinoma: univariate and multivariate analyses of a real-world study in Europe

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Julien Taieb, Thomas Seufferlein, Michele Reni, Daniel H. Palmer, John A. Bridgewater, Antonio Cubillo, Gerald W. Prager, Alice Vermeire, Fabienne Hédouin-Biville, Zhaoyang Teng, Teresa Macarulla

Expression signature and prognostic value of CREC gene family in human colorectal cancer

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Junya Ning, Min Liu, Jing Shen, Deping Wang, Lijuan Gao, Huiyu Li, Jimin Cao

An EMT-related genes signature as a prognostic biomarker for patients with endometrial cancer

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Yonghui Yu, Yiwen Zhang, Zhi Li, Yongshun Dong, Hongmei Huang, Binyao Yang, Eryong Zhao, Yongxiu Chen, Lei Yang, Jiachun Lu, Fuman Qiu

Association between surgical extent and recurrence in unilateral intermediate- to high-risk papillary thyroid cancer

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Siyuan Xu, Hui Huang, Huilei Dong, Xiaolei Wang, Zhengang Xu, Shaoyan Liu, Jie Liu

Recognising socio-cultural barriers while seeking early detection services for breast cancer: a study from a Universal Health Coverage setting in India

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