BMC Cancer

Nutrition therapy with high intensity interval training to improve prostate cancer-related fatigue in men on androgen deprivation therapy: a study protocol

• Open Access
• Study protocol

Brenton J. Baguley, Tina L. Skinner, Michael D. Leveritt, Olivia R. L. Wright

Waiting time for cancer treatment and mental health among patients with newly diagnosed esophageal or gastric cancer: a nationwide cohort study

• Open Access
• Research article

Huan Song, Fang Fang, Unnur Valdimarsdóttir, Donghao Lu, Therese M.-L. Andersson, Christina Hultman, Weimin Ye, Lars Lundell, Jan Johansson, Magnus Nilsson, Mats Lindblad

Analysis of cellular and molecular antitumor effects upon inhibition of SATB1 in glioblastoma cells

• Open Access
• Research article

Anja Frömberg, Michael Rabe, Henry Oppermann, Frank Gaunitz, Achim Aigner

Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration

• Open Access
• Research article

Khayal Al-Khayal, Ahmed Alafeefy, Mansoor-Ali Vaali-Mohammed, Amer Mahmood, Ahmed Zubaidi, Omar Al-Obeed, Zahid Khan, Maha Abdulla, Rehan Ahmad

Which symptoms are linked to a delayed presentation among melanoma patients? A retrospective study

• Open Access
• Research article

Sally Jane O’Shea, Zoe Rogers, Fiona Warburton, Amanda J. Ramirez, Julia A. Newton-Bishop, Lindsay J. L. Forbes

Perioperative changes in osteopontin and TGFβ1 plasma levels and their prognostic impact for radiotherapy in head and neck cancer

• Open Access
• Research article

Bülent Polat, Philipp Kaiser, Gisela Wohlleben, Thomas Gehrke, Agmal Scherzad, Matthias Scheich, Uwe Malzahn, Thomas Fischer, Dirk Vordermark, Michael Flentje

Biopsy of breast cancer metastases: patient characteristics and survival

• Open Access
• Research article

Shlomit Strulov Shachar, Tanya Mashiach, Georgeta Fried, Karen Drumea, Noa Shafran, Hyman B. Muss, Gil Bar-Sela

Prognostic values of EORTC QLQ-C30 and QLQ-HCC18 index-scores in patients with hepatocellular carcinoma – clinical application of health-related quality-of-life data

• Open Access
• Research article

Leung Li, Frankie KF Mo, Stephen L Chan, Edwin P Hui, Nelson SL Tang, Jane Koh, Linda KS Leung, Annette NY Poon, Joyce Hui, Cheuk M Chu, Kit F Lee, Brigette BY Ma, Paul BS Lai, Anthony TC Chan, Simon CH Yu, Winnie Yeo

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

• Open Access
• Research article

Gabriela Gremel, Dijana Djureinovic, Marjut Niinivirta, Alexander Laird, Oscar Ljungqvist, Henrik Johannesson, Julia Bergman, Per-Henrik Edqvist, Sanjay Navani, Naila Khan, Tushar Patil, Åsa Sivertsson, Mathias Uhlén, David J. Harrison, Gustav J. Ullenhag, Grant D. Stewart, Fredrik Pontén

Molecular chess? Hallmarks of anti-cancer drug resistance

• Open Access
• Review

Ian A. Cree, Peter Charlton

PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells

• Open Access
• Research article

Pinki Nandi, Gannareddy V. Girish, Mousumi Majumder, Xiping Xin, Elena Tutunea-Fatan, Peeyush K. Lala

Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1

• Open Access
• Research article

Messaouda Merzoug-Larabi, Caroline Spasojevic, Marianne Eymard, Caroline Hugonin, Christian Auclair, Manale Karam

Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA

• Open Access
• Research article

Nishitha Thumallapally, Ahmed Meshref, Mohammed Mousa, Terenig Terjanian

Expansion of the Milan criteria without any sacrifice: combination of the Hangzhou criteria with the pre-transplant platelet-to-lymphocyte ratio

• Open Access
• Research article

Weiliang Xia, Qinghong Ke, Hua Guo, Weilin Wang, Min Zhang, Yan Shen, Jian Wu, Xiao Xu, Sheng Yan, Jun Yu, Mangli Zhang, Shusen Zheng

A case report of primary unilateral adrenal NK/T cell lymphoma: good clinical outcome with trimodality treatment

• Open Access
• Case report

Liu Hu, Weimin Xu, Mingwei Wang, Pan Wang, Guang Han, Chi Lin

Sorafenib versus sunitinib as first-line treatment agents in Chinese patients with metastatic renal cell carcinoma: the largest multicenter retrospective analysis of survival and prognostic factors

• Open Access
• Research article

Hai-Liang Zhang, Xi-Nan Sheng, Xue-Song Li, Hong-Kai Wang, Zhi-Hong Chi, Zhi-Song He, Ding-Wei Ye, Jun Guo

Case report: whole exome sequencing of primary cardiac angiosarcoma highlights potential for targeted therapies

• Open Access
• Case report

Leah Zhrebker, Irene Cherni, Lara M. Gross, Margaret M. Hinshelwood, Merrick Reese, Jessica Aldrich, Joseph M. Guileyardo, William C. Roberts, David Craig, Daniel D. Von Hoff, Robert G. Mennel, John D. Carpten

Therapeutic vaccine targeting Epstein-Barr virus latent protein, LMP1, suppresses LMP1-expressing tumor growth and metastasis in vivo

• Open Access
• Research article

Mei-Chun Lin, Yong-Chong Lin, Syue-Ting Chen, Tai-Horng Young, Pei-Jen Lou

Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections

• Open Access
• Research article

Karen Marie Juul Sørensen, Theresa Meldgaard, Connie Jenning Melchjorsen, Agla J. Fridriksdottir, Henrik Pedersen, Ole William Petersen, Peter Kristensen

Growth, progression and chromosome instability of Neuroblastoma: a new scenario of tumorigenesis?

• Open Access
• Debate

Gian Paolo Tonini

Functional significance of CD105-positive cells in papillary renal cell carcinoma

• Open Access
• Research article

Damian Matak, Klaudia K. Brodaczewska, Cezary Szczylik, Irena Koch, Adam Myszczyszyn, Monika Lipiec, Slawomir Lewicki, Lukasz Szymanski, Robert Zdanowski, Anna M. Czarnecka

Lung adenocarcinoma expressing receptor for advanced glycation end-products with primary systemic AL amyloidosis: a case report and literature review

• Open Access
• Case report

Shouichi Okamoto, Shinsaku Togo, Ichiro Nagata, Kazue Shimizu, Yoshika Koinuma, Yukiko Namba, Jun Ito, Toshimasa Uekusa, Kazuhisa Takahashi

Establishing a xenograft mouse model of peritoneal dissemination of gastric cancer with organ invasion and fibrosis

• Open Access
• Research article

Mitsuyoshi Okazaki, Sachio Fushida, Shinichi Harada, Tomoya Tsukada, Jun Kinoshita, Katsunobu Oyama, Tomoharu Miyashita, Itasu Ninomiya, Tetsuo Ohta

Association between telomere length and the risk of colorectal cancer: a meta-analysis of observational studies

• Open Access
• Research article

Cho Naing, Kyan Aung, Pei Kuan Lai, Joon Wah Mak

Prognostic relevance of lactate dehydrogenase in advanced pancreatic ductal adenocarcinoma patients

• Open Access
• Research article

Yuanyuan Xiao, Wen Chen, Zhihui Xie, Zhenyi Shao, Hua Xie, Guoyou Qin, Naiqing Zhao

Intraperitoneal cisplatin and doxorubicin as maintenance chemotherapy for unresectable ovarian cancer: a case report

• Open Access
• Case report

Clemens B. Tempfer, Franziska Hartmann, Ziad Hilal, Günther A. Rezniczek

Biological toxicities as surrogate markers of efficacy in patients treated with mTOR inhibitors for metastatic renal cell carcinoma

• Open Access
• Research article

M. Jebali, R. Elaidi, M. Brizard, J. Fouque, C. Takouchop, B. Sabatier, S. Oudard, J. Medioni

Prognostic significance of Ki67 in Chinese women diagnosed with ER+/HER2− breast cancers by the 2015 St. Gallen consensus classification

• Open Access
• Research article

Yue Hu, Ran Gu, Jinghua Zhao, Yaping Yang, Fengtao Liu, Liang Jin, Kai Chen, Haixia Jia, Hongli Wang, Qiang Liu, Fengxi Su, Weijuan Jia

Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report

• Open Access
• Case report

Heidi M. Namløs, Olga Zaikova, Bodil Bjerkehagen, Daniel Vodák, Eivind Hovig, Ola Myklebost, Kjetil Boye, Leonardo A. Meza-Zepeda

A matched-pair study comparing whole-brain irradiation alone to radiosurgery or fractionated stereotactic radiotherapy alone in patients irradiated for up to three brain metastases

• Open Access
• Research article

Dirk Rades, Stefan Janssen, Liesa Dziggel, Oliver Blanck, Amira Bajrovic, Theo Veninga, Steven E. Schild

Parity and bladder cancer risk: a dose-response meta-analysis

• Open Access
• Research article

Yunjin Bai, Xiaoming Wang, Yubo Yang, Yin Tang, Jia Wang, Ping Han

Differential long-term stability of microRNAs and RNU6B snRNA in 12–20 year old archived formalin-fixed paraffin-embedded specimens

• Open Access
• Research article

Sarah B. Peskoe, John R. Barber, Qizhi Zheng, Alan K. Meeker, Angelo M. De Marzo, Elizabeth A. Platz, Shawn E. Lupold

miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway

• Open Access
• Research article

Kengo Kuroda, Tomokazu Fukuda, Marija Krstic-Demonacos, Constantinos Demonacos, Kazuhiko Okumura, Hiroshi Isogai, Miwa Hayashi, Kazuki Saito, Emiko Isogai

Cryptotanshinone activates AMPK-TSC2 axis leading to inhibition of mTORC1 signaling in cancer cells

• Open Access
• Research article

Wenxing Chen, Yanhong Pan, Siliang Wang, Yuping Liu, Guangying Chen, Liang Zhou, Wenting Ni, Aiyun Wang, Yin Lu

Chemotherapy-induced Sinusoidal Injury (CSI) score: a novel histologic assessment of chemotherapy-related hepatic sinusoidal injury in patients with colorectal liver metastasis

• Open Access
• Research article

Heather L. Stevenson, Mariana M. Prats, Eizaburo Sasatomi

Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma

• Open Access
• Research article

Ken Hatogai, Satoshi Fujii, Takashi Kojima, Hiroyuki Daiko, Toshihiko Doi, Atsushi Ohtsu, Atsushi Ochiai, Yuichi Takiguchi, Takayuki Yoshino

Pancreatic neuroendocrine tumor with metastasis to the spleen: a case report

• Open Access
• Case report

Yasunaru Sakuma, Yoshikazu Yasuda, Naohiro Sata, Yoshinori Hosoya, Atsushi Shimizu, Hirofumi Fujii, Daisuke Matsubara, Noriyuki Fukushima, Atsushi Miki, Misato Maeno, Alan Kawarai Lefor

Retrospective study of RAS/PIK3CA/BRAF tumor mutations as predictors of response to first-line chemotherapy with bevacizumab in metastatic colorectal cancer patients

• Open Access
• Research article

Izuma Nakayama, Eiji Shinozaki, Tomohiro Matsushima, Takeru Wakatsuki, Mariko Ogura, Takashi Ichimura, Masato Ozaka, Daisuke Takahari, Mitsukuni Suenaga, Keisho Chin, Nobuyuki Mizunuma, Kensei Yamaguchi

The acceleration of glucose accumulation in renal cell carcinoma assessed by FDG PET/CT demonstrated acquisition of resistance to tyrosine kinase inhibitor therapy

• Open Access
• Research article

Noboru Nakaigawa, Keiichi Kondo, Daiki Ueno, Kazuhiro Namura, Kazuhide Makiyama, Kazuki Kobayashi, Koichi Shioi, Ichiro Ikeda, Takeshi Kishida, Tomohiro Kaneta, Ryogo Minamimoto, Ukihide Tateishi, Tomio Inoue, Masahiro Yao

Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma

• Open Access
• Research article

Xiaoyan Han, Lijuan Wang, Hongfei Shi, Gaofeng Zheng, Jingsong He, Wenjun Wu, Jimin Shi, Guoqing Wei, Weiyan Zheng, Jie Sun, He Huang, Zhen Cai

Early life socioeconomic environment and mammographic breast density

• Open Access
• Research article

Parisa Tehranifar, Barbara A. Cohn, Julie D. Flom, Angeline Protacio, Piera Cirillo, L. H. Lumey, Karin B. Michels, Mary Beth Terry

The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases

• Open Access
• Research article

Xia Deng, Zhen Zheng, Baochai Lin, Huafang Su, Hanbin Chen, Shaoran Fei, Zhenghua Fei, Lihao Zhao, Xiance Jin, Cong-Ying Xie

Swallowing interventions for the treatment of dysphagia after head and neck cancer: a systematic review of behavioural strategies used to promote patient adherence to swallowing exercises

• Open Access
• Research article

Roganie Govender, Christina H. Smith, Stuart A. Taylor, Helen Barratt, Benjamin Gardner

Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer

• Open Access
• Research article

Simone Brandt, Eleftherios P. Samartzis, Anne-Katrin Zimmermann, Daniel Fink, Holger Moch, Aurelia Noske, Konstantin J. Dedes

The miR-34a-5p promotes the multi-chemoresistance of osteosarcoma via repression of the AGTR1 gene

• Open Access
• Research article

Youguang Pu, Fangfang Zhao, Yinpeng Li, Mingda Cui, Haiyan Wang, Xianghui Meng, Shanbao Cai

MALAT1 promoted invasiveness of gastric adenocarcinoma

• Open Access
• Research article

Na Keum Lee, Jung Hwa Lee, Cristina Ivan, Hui Ling, Xinna Zhang, Chan Hyuk Park, George A. Calin, Sang Kil Lee

Incidence of solitary pulmonary nodules in Northeastern France: a population-based study in five regions

• Open Access
• Research article

Émilie Marrer, Damien Jolly, Patrick Arveux, Catherine Lejeune, Marie-Christine Woronoff-Lemsi, Jérémie Jégu, Francis Guillemin, Michel Velten

Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer

• Open Access
• Research article

Jesper Andreas Palshof, Estrid Vilma Solyom Høgdall, Tim Svenstrup Poulsen, Dorte Linnemann, Benny Vittrup Jensen, Per Pfeiffer, Line Schmidt Tarpgaard, Nils Brünner, Jan Stenvang, Mette Yilmaz, Dorte Lisbet Nielsen

Evaluation of the cytotoxicity of the Bithionol - cisplatin combination in a panel of human ovarian cancer cell lines

• Open Access
• Research article

Vijayalakshmi N. Ayyagari, Tsung-han Jeff Hsieh, Paula L. Diaz-Sylvester, Laurent Brard

Delta-like 4/Notch signaling promotes Apc Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms

• Open Access
• Research article

Marina Badenes, Alexandre Trindade, Hugo Pissarra, Luís Lopes-da-Costa, António Duarte

Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer

• Open Access
• Research article

Maria Laura Pati, John R. Hornick, Mauro Niso, Francesco Berardi, Dirk Spitzer, Carmen Abate, William Hawkins

Genomic pathways modulated by Twist in breast cancer

• Open Access
• Research article

Farhad Vesuna, Yehudit Bergman, Venu Raman

Detection of circulating tumor cells with CK20 RT-PCR is an independent negative prognostic marker in colon cancer patients – a prospective study

• Open Access
• Research article

Sebastian Hinz, Alexander Hendricks, Amke Wittig, Clemens Schafmayer, Jürgen Tepel, Holger Kalthoff, Thomas Becker, Christian Röder

Narrow band imaging versus lugol chromoendoscopy to diagnose squamous cell carcinoma of the esophagus: a systematic review and meta-analysis

• Open Access
• Research article

Flavio Hiroshi Ananias Morita, Wanderley Marques Bernardo, Edson Ide, Rodrigo Silva Paula Rocha, Julio Cesar Martins Aquino, Mauricio Kazuyoshi Minata, Kendi Yamazaki, Sergio Barbosa Marques, Paulo Sakai, Eduardo Guimarães Hourneaux de Moura

Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells

• Open Access
• Research article

Peiju Qiu, Siwen Wang, Ming Liu, He Ma, Xuan Zeng, Meng Zhang, Lingling Xu, Yidi Cui, Huixin Xu, Yang Tang, Yanli He, Lijuan Zhang

D-dimer is an essential accompaniment of circulating tumor cells in gastric cancer

• Open Access
• Research article

Dongmei Diao, Yao Cheng, Yongchun Song, Hao Zhang, Zhangjian Zhou, Chengxue Dang

Incidence of Venous Thromboembolism in cancer patients treated with Cisplatin based chemotherapy — a cohort study

• Open Access
• Research article

Muhammad Nauman Zahir, Quratulain Shaikh, Munira Shabbir-Moosajee, Adnan Abdul Jabbar

Microvascular invasion has limited clinical values in hepatocellular carcinoma patients at Barcelona Clinic Liver Cancer (BCLC) stages 0 or B

• Open Access
• Research article

Cheng Huang, Xiao-Dong Zhu, Yuan Ji, Guang-Yu Ding, Guo-Ming Shi, Ying-Hao Shen, Jian Zhou, Jia Fan, Hui-Chuan Sun

Risk factors for aspiration pneumonia after definitive chemoradiotherapy or bio-radiotherapy for locally advanced head and neck cancer: a monocentric case control study

• Open Access
• Research article

Sadayuki Kawai, Tomoya Yokota, Yusuke Onozawa, Satoshi Hamauchi, Akira Fukutomi, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Akiko Todaka, Takahiro Tsushima, Yukio Yoshida, Yosuke Kito, Keita Mori, Hirofumi Yasui

High expression of micro RNA-135A in hepatocellular carcinoma is associated with recurrence within 12 months after resection

• Open Access
• Research article

Johann von Felden, Denise Heim, Kornelius Schulze, Till Krech, Florian Ewald, Björn Nashan, Ansgar W. Lohse, Henning Wege

Evaluation of the ablation margin of hepatocellular carcinoma using CEUS-CT/MR image fusion in a phantom model and in patients

• Open Access
• Research article

Kai Li, Zhongzhen Su, Erjiao Xu, Qiannan Huang, Qingjing Zeng, Rongqin Zheng

Prognostic histological factors in patients with esophageal squamous cell carcinoma after preoperative chemoradiation followed by surgery

• Open Access
• Research article

Cheng-Che Tu, Po-Kuei Hsu, Ling-I Chien, Wan-Chen Liu, Chien-Sheng Huang, Chih-Cheng Hsieh, Han-Shui Hsu, Yu-Chung Wu

Genetic polymorphisms of SCN9A are associated with oxaliplatin-induced neuropathy

• Open Access
• Research article

María Sereno, Gerardo Gutiérrez-Gutiérrez, Juan Moreno Rubio, María Apellániz-Ruiz, Lara Sánchez-Barroso, Enrique Casado, Sandra Falagan, Miriam López-Gómez, María Merino, César Gómez-Raposo, Nuria Rodriguez-Salas, Francisco Zambrana Tébar, Cristina Rodríguez-Antona

Race and BMI modify associations of calcium and vitamin D intake with prostate cancer

• Open Access
• Research article

Ken Batai, Adam B. Murphy, Maria Ruden, Jennifer Newsome, Ebony Shah, Michael A. Dixon, Elizabeth T. Jacobs, Courtney M. P. Hollowell, Chiledum Ahaghotu, Rick A. Kittles

Stepwise addition of genetic changes correlated with histological change from “well-differentiated” to “sarcomatoid” phenotypes: a case report

• Open Access
• Case report

Taichiro Goto, Yosuke Hirotsu, Hitoshi Mochizuki, Takahiro Nakagomi, Toshio Oyama, Kenji Amemiya, Masao Omata

Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing – a case report

• Open Access
• Case report

Nadejda Valtcheva, Franziska M. Lang, Aurelia Noske, Eleftherios P. Samartzis, Anna-Maria Schmidt, Elisa Bellini, Daniel Fink, Holger Moch, Markus Rechsteiner, Konstantin J. Dedes, Peter J. Wild

Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

• Open Access
• Research article

Sridhar Murahari, Aimee L. Jalkanen, Samuel K. Kulp, Ching-Shih Chen, Jaime F. Modiano, Cheryl A. London, William C. Kisseberth

Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

• Open Access
• Research article

Shalini V. Rao, Guri Solum, Barbara Niederdorfer, Kristin G. Nørsett, Geir Bjørkøy, Liv Thommesen

Low glycemic index diet, exercise and vitamin D to reduce breast cancer recurrence (DEDiCa): design of a clinical trial

• Open Access
• Study protocol

Livia S.A. Augustin, Massimo Libra, Anna Crispo, Maria Grimaldi, Michele De Laurentiis, Massimo Rinaldo, Massimiliano D’Aiuto, Francesca Catalano, Giuseppe Banna, Francesco Ferrau’, Rosalba Rossello, Diego Serraino, Ettore Bidoli, Samuele Massarut, Guglielmo Thomas, Davide Gatti, Ernesta Cavalcanti, Monica Pinto, Gabriele Riccardi, Edward Vidgen, Cyril W.C. Kendall, David J.A. Jenkins, Gennaro Ciliberto, Maurizio Montella

Prognostic value of CC-chemokine receptor seven expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor

• Open Access
• Research article

Yu Xia, Li Liu, Ying Xiong, Qi Bai, Jiajun Wang, Wei Xi, Yang Qu, Jiejie Xu, Jianming Guo

Erratum to: Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer

• Open Access
• Erratum

Wendy Demark-Wahnefried, Jeffery W. Nix, Gary R. Hunter, Soroush Rais-Bahrami, Renee A. Desmond, Balu Chacko, Casey D. Morrow, Maria Azrad, Andrew D. Frugé, Yuko Tsuruta, Travis Ptacek, Scott A. Tully, Roanne Segal, William E. Grizzle

Primary neuroendocrine breast carcinomas are associated with poor local control despite favourable biological profile: a retrospective clinical study

• Open Access
• Research article

Nelli Roininen, Sari Takala, Kirsi-Maria Haapasaari, Arja Jukkola-Vuorinen, Johanna Mattson, Päivi Heikkilä, Peeter Karihtala

Neovascularization of hepatocellular carcinoma in a nude mouse orthotopic liver cancer model: a morphological study using X-ray in-line phase-contrast imaging

• Open Access
• Research article

Beilei Li, Yiqiu Zhang, Weizhong Wu, Guohao Du, Liang Cai, Hongcheng Shi, Shaoliang Chen

An increase in physical activity after colorectal cancer surgery is associated with improved recovery of physical functioning: a prospective cohort study

• Open Access
• Research article

Moniek van Zutphen, Renate M. Winkels, Fränzel J. B. van Duijnhoven, Suzanne A. van Harten-Gerritsen, Dieuwertje E. G. Kok, Peter van Duijvendijk, Henk K. van Halteren, Bibi M. E. Hansson, Flip M. Kruyt, Ernst J. Spillenaar Bilgen, Johannes H. W. de Wilt, Jaap J. Dronkers, Ellen Kampman

The feasibility and advantage of uniportal video-assisted thoracoscopic surgery (VATS) in pulmonary lobectomy

• Open Access
• Research article

Linlin Wang, Dabei Liu, Jibin Lu, Suning Zhang, Xueying Yang

Upregulation of the proto-oncogene Bmi-1 predicts a poor prognosis in pediatric acute lymphoblastic leukemia

• Open Access
• Research article

Hong-Xia Peng, Xiao-Dan Liu, Zi-Yan Luo, Xiao-Hong Zhang, Xue-Qun Luo, Xiao Chen, Hua Jiang, Ling Xu

An approach to forecast human cancer by profiling microRNA expressions from NGS data

• Open Access
• Research Article

A. Salim, R. Amjesh, S. S. Vinod Chandra

Lung cells support osteosarcoma cell migration and survival

• Open Access
• Research article

Shibing Yu, Mitchell Stephen Fourman, Adel Mahjoub, Jonathan Brendan Mandell, Jared Anthony Crasto, Nicholas Giuseppe Greco, Kurt Richard Weiss

A non-invasive tool for detecting cervical cancer odor by trained scent dogs

• Open Access
• Research article

Héctor Guerrero-Flores, Teresa Apresa-García, Ónix Garay-Villar, Alejandro Sánchez-Pérez, David Flores-Villegas, Artfy Bandera-Calderón, Raúl García-Palacios, Teresita Rojas-Sánchez, Pablo Romero-Morelos, Verónica Sánchez-Albor, Osvaldo Mata, Víctor Arana-Conejo, Jesús Badillo-Romero, Keiko Taniguchi, Daniel Marrero-Rodríguez, Mónica Mendoza-Rodríguez, Miriam Rodríguez-Esquivel, Víctor Huerta-Padilla, Andrea Martínez-Castillo, Irma Hernández-Gallardo, Ricardo López-Romero, Cindy Bandala, Juan Rosales-Guevara, Mauricio Salcedo

Adjuvant radiotherapy improves cause specific survival in stage II, not stage III mucinous carcinoma of the rectum

• Open Access
• Research article

Qingguo Li, Yaqi Li, Weixing Dai, Sheng Wang, Ye Xu, Xinxiang Li, Sanjun Cai

Study protocol of the TIRED study: a randomised controlled trial comparing either graded exercise therapy for severe fatigue or cognitive behaviour therapy with usual care in patients with incurable cancer

• Open Access
• Study protocol

Hanneke Poort, Constans A. H. H. V. M. Verhagen, Marlies E. W. J. Peters, Martine M. Goedendorp, A. Rogier T. Donders, Maria T. E. Hopman, Maria W. G. Nijhuis-van der Sanden, Thea Berends, Gijs Bleijenberg, Hans Knoop

Life situation and psychosocial care of adolescent and young adult (AYA) cancer patients – study protocol of a 12-month prospective longitudinal study

• Open Access
• Study protocol

Katja Leuteritz, Michael Friedrich, Erik Nowe, Annekathrin Sender, Yve Stöbel-Richter, Kristina Geue

The Norwegian dietary guidelines and colorectal cancer survival (CRC-NORDIET) study: a food-based multicentre randomized controlled trial

• Open Access
• Study protocol

Hege Berg Henriksen, Hanna Ræder, Siv Kjølsrud Bøhn, Ingvild Paur, Ane Sørlie Kværner, Siv Åshild Billington, Morten Tandberg Eriksen, Gro Wiedsvang, Iris Erlund, Arne Færden, Marit Bragelien Veierød, Manuela Zucknick, Sigbjørn Smeland, Rune Blomhoff

Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort

• Open Access
• Research article

Robert A. Vierkant, Amy C. Degnim, Derek C. Radisky, Daniel W. Visscher, Ethan P. Heinzen, Ryan D. Frank, Stacey J. Winham, Marlene H. Frost, Christopher G. Scott, Matthew R. Jensen, Karthik Ghosh, Armando Manduca, Kathleen R. Brandt, Dana H. Whaley, Lynn C. Hartmann, Celine M. Vachon

Cancers of unknown primary diagnosed during hospitalization: a population-based study

• Open Access
• Research article

William Jones, Gwen Allardice, Iona Scott, Karin Oien, David Brewster, David S. Morrison

HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation

• Open Access
• Research article

Martin McLaughlin, Holly E. Barker, Aadil A. Khan, Malin Pedersen, Magnus Dillon, David C. Mansfield, Radhika Patel, Joan N. Kyula, Shreerang A. Bhide, Kate L. Newbold, Christopher M. Nutting, Kevin J. Harrington

Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma

• Open Access
• Research article

Hoon Hur, In-Hye Ham, Dakeun Lee, Hyejin Jin, Kristina Y. Aguilera, Hye Jeong Oh, Sang-Uk Han, Ji Eun Kwon, Young-Bae Kim, Ke Ding, Rolf A. Brekken

The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo

• Open Access
• Research article

Nicole Lavender, Jinming Yang, Sheau-Chiann Chen, Jiqing Sai, C. Andrew Johnson, Philip Owens, Gregory D. Ayers, Ann Richmond

BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study

• Open Access
• Research article

Shingo Miyamoto, Fusanori Yotsumoto, Taeko Ueda, Tatsuya Fukami, Ayako Sanui, Kohei Miyata, Sung Ouk Nam, Satoshi Fukagawa, Takahiro Katsuta, Miyako Maehara, Haruhiko Kondo, Daisuke Miyahara, Kyoko Shirota, Toshiyuki Yoshizato, Masahide Kuroki, Hiroaki Nishikawa, Keijiro Saku, Yoshio Tsuboi, Kenji Ishitsuka, Yasushi Takamatsu, Kazuo Tamura, Akira Matsunaga, Toru Hachisuga, Shinsuke Nishino, Takashi Odawara, Kazuhiro Maeda, Sadao Manabe, Toyokazu Ishikawa, Yoshinobu Okuno, Minako Ohishi, Tomoya Hikita, Hiroto Mizushima, Ryo Iwamoto, Eisuke Mekada

Higher IGFBP-1 to IGF-1 serum ratio predicts unfavourable survival in patients with nasopharyngeal carcinoma

• Open Access
• Research article

Xinwei Feng, Jianhua Lin, Shan Xing, Wanli Liu, Ge Zhang

Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma

• Open Access
• Research article

Gang Wan, Fangyuan Gao, Jialiang Chen, Yuxin Li, Mingfan Geng, Le Sun, Yao Liu, Huimin Liu, Xue Yang, Rui Wang, Ying Feng, Xianbo Wang

Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines

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Elisa Lázaro-Ibáñez, Taral R. Lunavat, Su Chul Jang, Carmen Escobedo-Lucea, Jorge Oliver-De La Cruz, Pia Siljander, Jan Lötvall, Marjo Yliperttula

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells

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Sergey A. Dyshlovoy, Ramin Madanchi, Jessica Hauschild, Katharina Otte, Winfried H. Alsdorf, Udo Schumacher, Vladimir I. Kalinin, Alexandra S. Silchenko, Sergey A. Avilov, Friedemann Honecker, Valentin A. Stonik, Carsten Bokemeyer, Gunhild von Amsberg

Cancer mortality in former East and West Germany: a story of unification?

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Daniel Medenwald, Dirk Vordermark, Christian T. Dietzel

A systematic review of geographical differences in management and outcomes for colorectal cancer in Australia

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• Research article

Michael J. Ireland, Sonja March, Fiona Crawford-Williams, Mandy Cassimatis, Joanne F. Aitken, Melissa K. Hyde, Suzanne K. Chambers, Jiandong Sun, Jeff Dunn

The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in lung cancer patients

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Li Zhang, Dan Liu, Lei Li, Dan Pu, Ping Zhou, Yuting Jing, He Yu, Yanwen Wang, Yihan Zhu, Yanqi He, Yalun Li, Shuang Zhao, Zhixin Qiu, Weimin Li

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk

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Liv B. Gansmo, Merete Bjørnslett, Mari Kyllesø Halle, Helga B. Salvesen, Pål Romundstad, Kristian Hveem, Lars Vatten, Anne Dørum, Per E. Lønning, Stian Knappskog

The Women’s wellness after cancer program: a multisite, single-blinded, randomised controlled trial protocol

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• Study protocol

Debra Anderson, Charrlotte Seib, Dian Tjondronegoro, Jane Turner, Leanne Monterosso, Amanda McGuire, Janine Porter-Steele, Wei Song, Patsy Yates, Neil King, Leonie Young, Kate White, Kathryn Lee, Sonj Hall, Mei Krishnasamy, Kathy Wells, Sarah Balaam, Alexandra L. McCarthy

Curcumin decreases malignant characteristics of glioblastoma stem cells via induction of reactive oxygen species

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Zachary C. Gersey, Gregor A. Rodriguez, Eric Barbarite, Anthony Sanchez, Winston M. Walters, Kelechi C. Ohaeto, Ricardo J. Komotar, Regina M. Graham

Optitrain: a randomised controlled exercise trial for women with breast cancer undergoing chemotherapy

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• Study protocol

Y. Wengström, K. A. Bolam, S. Mijwel, C. J. Sundberg, M. Backman, M. Browall, J. Norrbom, H. Rundqvist

Body mass index modifies the relationship between γ-H2AX, a DNA damage biomarker, and pathological complete response in triple-negative breast cancer

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Maddalena Barba, Patrizia Vici, Laura Pizzuti, Luigi Di Lauro, Domenico Sergi, Anna Di Benedetto, Cristiana Ercolani, Francesca Sperati, Irene Terrenato, Claudio Botti, Lucia Mentuccia, Laura Iezzi, Teresa Gamucci, Clara Natoli, Ilio Vitale, Marcella Mottolese, Ruggero De Maria, Marcello Maugeri-Saccà

Stromal alterations in ovarian cancers via wavelength dependent Second Harmonic Generation microscopy and optical scattering

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Karissa B. Tilbury, Kirby R. Campbell, Kevin W. Eliceiri, Sana M. Salih, Manish Patankar, Paul J. Campagnola

Implementing exercise in cancer care: study protocol to evaluate a community-based exercise program for people with cancer

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• Study protocol

Prue Cormie, Stephanie Lamb, Robert U. Newton, Lani Valentine, Sandy McKiernan, Nigel Spry, David Joseph, Dennis R. Taaffe, Christopher M. Doran, Daniel A. Galvão

Microparticles shed from multidrug resistant breast cancer cells provide a parallel survival pathway through immune evasion

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Ritu Jaiswal, Michael S. Johnson, Deep Pokharel, S. Rajeev Krishnan, Mary Bebawy

CLASP2 is involved in the EMT and early progression after transurethral resection of the bladder tumor

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Bisong Zhu, Lin Qi, Sulai Liu, Wentao Liu, Zhenyu Ou, Minfeng Chen, Longfei Liu, Xiongbing Zu, Jun Wang, Yuan Li

Improving adherence to colorectal cancer surveillance guidelines: results of a randomised controlled trial

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Mariko Carey, Robert Sanson-Fisher, Finlay Macrae, Emilie Cameron, David Hill, Catherine D’Este, Christopher Doran

Mechanism of action of trabectedin in desmoplastic small round cell tumor cells

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S. Uboldi, I. Craparotta, G. Colella, E. Ronchetti, L. Beltrame, S. Vicario, S. Marchini, N. Panini, G. Dagrada, F. Bozzi, S. Pilotti, C. M. Galmarini, M. D’Incalci, R. Gatta

Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts

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Lina Leiss, Ercan Mutlu, Anne Øyan, Tao Yan, Oleg Tsinkalovsky, Linda Sleire, Kjell Petersen, Mohummad Aminur Rahman, Mireille Johannessen, Sidhartha S. Mitra, Hege K. Jacobsen, Krishna M. Talasila, Hrvoje Miletic, Inge Jonassen, Xingang Li, Nicolaas H. Brons, Karl-Henning Kalland, Jian Wang, Per Øyvind Enger

microRNA-29c inhibits cell proliferation by targeting NASP in human gastric cancer

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Beiqin Yu, Xuehua Chen, Jianfang Li, Qinlong Gu, Zhenggang Zhu, Chen Li, Liping Su, Bingya Liu

Preliminary stop of the TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC) trial

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• Correspondence

M. M. Koeneman, A. J. Kruse, L. F. S. Kooreman, A. zur Hausen, A. H. N. Hopman, S. J. S. Sep, T. Van Gorp, B. F. M. Slangen, H. J. van Beekhuizen, A. J. M. van de Sande, C. G. Gerestein, H. W. Nijman, R. F. P. M. Kruitwagen

Treatment patterns and survival in an exhaustive French cohort of pazopanib-eligible patients with metastatic soft tissue sarcoma (STS)

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Isabelle Ray-Coquard, Olivier Collard, Françoise Ducimetiere, Mathieu Laramas, Florence Mercier, Nadine Ladarre, Stephanie Manson, Bertrand Tehard, Sébastien Clippe, Jean-Philippe Suchaud, Laetitia Stefani, Jean-Yves Blay

Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design

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• Study protocol

Lisanne S. Rigter, Manon C. W. Spaander, Leon M. Moons, Tanya M. Bisseling, Berthe M. P. Aleman, Jan Paul de Boer, Pieternella J. Lugtenburg, Cecile P. M. Janus, Eefke J. Petersen, Judith M. Roesink, John M. M. Raemaekers, Richard W. M. van der Maazen, Annemieke Cats, Eveline M. A. Bleiker, Petur Snaebjornsson, Beatriz Carvalho, Iris Lansdorp-Vogelaar, Katarzyna Jóźwiak, Hein te Riele, Gerrit A. Meijer, Flora E. van Leeuwen, Monique E. van Leerdam

Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer

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Cong Lin, Christof J. Majoor, Joris J. T. H. Roelofs, Martijn D. de Kruif, Hugo M. Horlings, Keren Borensztajn, C. Arnold Spek

Thyroid fine-needle aspiration biopsy positively correlates with increased diagnosis of thyroid cancer in South Korean patients

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Yoon Jae Cho, Do Young Kim, Eun-Cheol Park, Kyu-Tae Han

Immunohistochemical determination of estrogen and progesterone receptors in breast cancer: relationship with clinicopathologic factors in 302 patients in Ivory Coast

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Ahoua Benjamin Effi, Nguiessan Alphonse Aman, Baumaney Sylvanus Koui, Kouadio Donatien Koffi, Zie Cheick Traoré, Mohamed Kouyate

Molecular stool testing as an alternative for surveillance colonoscopy: a cross-sectional cohort study

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• Study protocol

Meta C. J. van Lanschot, Beatriz Carvalho, Veerle M. H. Coupé, Manon van Engeland, Evelien Dekker, Gerrit A. Meijer

Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

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Ying Xiong, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Qi Bai, Yang Qu, Jiejie Xu, Jianming Guo

Enhanced and long term immunogenicity of a Her-2/neu multi-epitope vaccine conjugated to the carrier CRM197 in conjunction with the adjuvant Montanide

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Joshua Tobias, Joanna Jasinska, Karin Baier, Michael Kundi, Nicholas Ede, Christoph Zielinski, Ursula Wiedermann

Case report: rapid and durable response to PDGFR targeted therapy in a child with refractory multiple infantile myofibromatosis and a heterozygous germline mutation of the PDGFRB gene

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• Case report

Peter Mudry, Ondrej Slaby, Jakub Neradil, Jana Soukalova, Kristyna Melicharkova, Ondrej Rohleder, Marta Jezova, Anna Seehofnerova, Elleni Michu, Renata Veselska, Jaroslav Sterba

Meta-analysis of gene expression in relapsed childhood B-acute lymphoblastic leukemia

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Yock-Ping Chow, Hamidah Alias, Rahman Jamal

Inhibition of glioblastoma dispersal by the MEK inhibitor PD0325901

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Stephen Shannon, Dongxuan Jia, Ildiko Entersz, Paul Beelen, Miao Yu, Christian Carcione, Jonathan Carcione, Aria Mahtabfar, Connan Vaca, Michael Weaver, David Shreiber, Jeffrey D. Zahn, Liping Liu, Hao Lin, Ramsey A. Foty

Supporting adherence to oral anticancer agents: clinical practice and clues to improve care provided by physicians, nurse practitioners, nurses and pharmacists

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Lonneke Timmers, Christel C. L. M. Boons, Mathieu Verbrugghe, Bart J. F. van den Bemt, Ann Van Hecke, Jacqueline G. Hugtenburg

Photodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells

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Laura Marise de Freitas, Rodolfo Bortolozo Serafim, Juliana Ferreira de Sousa, Thaís Fernanda Moreira, Cláudia Tavares dos Santos, Amanda Martins Baviera, Valeria Valente, Christiane Pienna Soares, Carla Raquel Fontana

Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer

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Hans-Peter Sinn, Andreas Schneeweiss, Marius Keller, Kornelia Schlombs, Mark Laible, Julia Seitz, Sotirios Lakis, Elke Veltrup, Peter Altevogt, Sebastian Eidt, Ralph M. Wirtz, Frederik Marmé

Adipokines, insulin resistance, and adiposity as a predictors of metabolic syndrome in child survivors of lymphoma and acute lymphoblastic leukemia of a developing country

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Lourdes Barbosa-Cortés, Mardia López-Alarcón, Juan Manuel Mejía-Aranguré, Miguel Klünder-Klünder, María del Carmen Rodríguez-Zepeda, Hugo Rivera-Márquez, Alan de la Vega-Martínez, Jorge Martin-Trejo, Juan Shum-Luis, Karina Solis-Labastida, Enrique López-Aguilar, Guadalupe Matute-González, Roberto Bernaldez-Rios

Enhanced expression of Vastatin inhibits angiogenesis and prolongs survival in murine orthotopic glioblastoma model

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Yi Li, Jun Li, Yat Ming Woo, Zan Shen, Hong Yao, Yijun Cai, Marie Chia-mi Lin, Wai Sang Poon

First insight into the somatic mutation burden of neurofibromatosis type 2-associated grade I and grade II meningiomas: a case report comprehensive genomic study of two cranial meningiomas with vastly different clinical presentation

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• Case report

Ramita Dewan, Alexander Pemov, Amalia S. Dutra, Evgenia D. Pak, Nancy A. Edwards, Abhik Ray-Chaudhury, Nancy F. Hansen, Settara C. Chandrasekharappa, James C. Mullikin, Ashok R. Asthagiri, John D. Heiss, Douglas R. Stewart, Anand V. Germanwala

Analysis of prognostic factors in patients with newly diagnosed diffuse large B-cell lymphoma and skeletal involvement

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Nicola Lehners, Isabelle Krämer, Maral Saadati, Axel Benner, Anthony D. Ho, Mathias Witzens-Harig

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy

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Jessica Pahle, Lutz Menzel, Nicole Niesler, Dennis Kobelt, Jutta Aumann, Maria Rivera, Wolfgang Walther

The clinical picture of cachexia: a mosaic of different parameters (experience of 503 patients)

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S. Schwarz, O. Prokopchuk, K. Esefeld, S. Gröschel, J. Bachmann, S. Lorenzen, H. Friess, M. Halle, M. E. Martignoni

Clinicopathologic characteristics and prognostic factors for primary spinal epidural lymphoma: report on 36 Chinese patients and review of the literature

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Le Xiong, Ling-Min Liao, Jian-Wu Ding, Zhi-Lin Zhang, An-Wen Liu, Long Huang

Rechallenge and maintenance therapy using cetuximab and chemotherapy administered to a patient with metastatic colorectal cancer

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• Case report

Jian Ma, Quan-liang Yang, Yang Ling

Effect of myeloid differentiation primary response gene 88 on expression profiles of genes during the development and progression of Helicobacter-induced gastric cancer

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Ivonne Lozano-Pope, Arnika Sharma, Michael Matthias, Kelly S. Doran, Marygorret Obonyo

Safety and efficacy of lobaplatin combined with 5-fluorouracil as first-line induction chemotherapy followed by lobaplatin-radiotherapy in locally advanced nasopharyngeal carcinoma: preliminary results of a prospective phase II trial

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Liang-Ru Ke, Wei-Xiong Xia, Wen-Ze Qiu, Xin-Jun Huang, Jing Yang, Ya-Hui Yu, Hu Liang, Guo-Ying Liu, Yan-Fang Ye, Yan-Qun Xiang, Xiang Guo, Xing Lv

CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity

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Zhao-wei Gao, Hui-ping Wang, Fang Lin, Xi Wang, Min Long, Hui-zhong Zhang, Ke Dong

Viral E6 is overexpressed via high viral load in invasive cervical cancer with episomal HPV16

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Die Hong, Jia Liu, Ying Hu, Xiaonan Lu, Baohua Li, Yang Li, Dongxiao Hu, Weiguo Lu, Xing Xie, Xiaodong Cheng

A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients

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Berta Laquente, Jose Lopez-Martin, Donald Richards, Gerald Illerhaus, David Z. Chang, George Kim, Philip Stella, Dirk Richel, Cezary Szcylik, Stefano Cascinu, G. L. Frassineti, Tudor Ciuleanu, Karla Hurt, Scott Hynes, Ji Lin, Aimee Bence Lin, Daniel Von Hoff, Emiliano Calvo

Up-regulation of miR-146a increases the sensitivity of non-small cell lung cancer to DDP by downregulating cyclin J

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Lin Shi, Zhaozhong Xu, Gang Wu, Xiaoting Chen, Yuanyuan Huang, Yanjing Wang, Weiqiang Jiang, Bin Ke

Clinical performance evaluation of a sensitive, rapid low-throughput test for KRAS mutation analysis using formalin-fixed, paraffin-embedded tissue samples

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Christine Weyn, Sofie Van Raemdonck, Robina Dendooven, Vincent Maes, Karen Zwaenepoel, Suzan Lambin, Patrick Pauwels

miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4

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Zheng He, Lianhua Yu, Shiyi Luo, Mingzhen Li, Junbo Li, Qi Li, Yi Sun, Chengbin Wang

Relationships between longitudinal neutrophil to lymphocyte ratios, body weight changes, and overall survival in patients with non-small cell lung cancer

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B. A. Derman, J. N. Macklis, M. S. Azeem, S. Sayidine, S. Basu, M. Batus, F. Esmail, J. A. Borgia, P. Bonomi, M. J. Fidler

Papillary thyroid microcarcinoma: the significance of high risk features

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Nori L. Bradley, Sam M. Wiseman

Myopericytoma occurrence in the liver and stomach space: imaging performance

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Zhihua Chen, Wenjie Liang

Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective cohort study

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Kazumi Komaki, Tetsuro Kusaba, Mai Tanaka, Hiroshi Kado, Yayoi Shiotsu, Masahiro Matsui, Atsushi Shiozaki, Hiroshi Nakano, Takeshi Ishikawa, Hitoshi Fujiwara, Hideyuki Konishi, Yoshito Itoh, Satoaki Matoba, Keiichi Tamagaki

The tumor suppressor RhoBTB1 controls Golgi integrity and breast cancer cell invasion through METTL7B

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Caroline M. McKinnon, Harry Mellor

Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree

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Lorena Fernández-Martínez, José Antonio Villegas, Íñigo Santamaría, Ana S. Pitiot, Marta G. Alvarado, Soledad Fernández, Héctor Torres, Ángeles Paredes, Pilar Blay, Milagros Balbín

Wogonin as a targeted therapeutic agent for EBV (+) lymphoma cells involved in LMP1/NF-κB/miR-155/PU.1 pathway

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Xue Wu, Ping Liu, Haijun Zhang, Yuan Li, Jumah Masoud Mohammad Salmani, Fei Wang, Ke Yang, Rong Fu, Zhewei Chen, Baoan Chen

WD-repeat protein WDR13 is a novel transcriptional regulator of c-Jun and modulates intestinal homeostasis in mice

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Vijay Pratap Singh, Saritha Katta, Satish Kumar

Characterization of BRCA1 and BRCA2 variants in multi-ethnic Asian cohort from a Malaysian case-control study

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Kah Nyin Lai, Weang Kee Ho, In Nee Kang, Peter Choon Eng Kang, Sze Yee Phuah, Shivaani Mariapun, Cheng-Har Yip, Nur Aishah Mohd Taib, Soo-Hwang Teo

Validation of an NGS mutation detection panel for melanoma

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Anne Reiman, Hugh Kikuchi, Daniela Scocchia, Peter Smith, Yee Wah Tsang, David Snead, Ian A Cree

High-dose chemotherapy and autologous stem cell transplantation of patients with multiple myeloma in an outpatient setting

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Katharina Lisenko, Sandra Sauer, Thomas Bruckner, Gerlinde Egerer, Hartmut Goldschmidt, Jens Hillengass, Johann W. Schmier, Sofia Shah, Mathias Witzens-Harig, Anthony D. Ho, Patrick Wuchter

Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report

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• Case report

Yoshiki Tsujii, Yoshito Hayashi, Akira Maekawa, Tetsuji Fujinaga, Kengo Nagai, Shunsuke Yoshii, Akihiko Sakatani, Satoshi Hiyama, Shinichiro Shinzaki, Hideki Iijima, Tetsuo Takehara

The effects of exercise on pain, fatigue, insomnia, and health perceptions in patients with operable advanced stage rectal cancer prior to surgery: a pilot trial

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Jennifer Brunet, Shaunna Burke, Michael P.W. Grocott, Malcolm A. West, Sandy Jack

Early evaluation of sunitinib for the treatment of advanced gastroenteropancreatic neuroendocrine neoplasms via CT imaging: RECIST 1.1 or Choi Criteria?

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Yanji Luo, Jie Chen, Kun Huang, Yuan Lin, Minhu Chen, Ling Xu, Zi-Ping Li, Shi-Ting Feng

Do pre-diagnosis primary care consultation patterns explain deprivation-specific differences in net survival among women with breast cancer? An examination of individually-linked data from the UK West Midlands cancer registry, national screening programme and Clinical Practice Research Datalink

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M. Morris, L. M. Woods, K. Bhaskaran, B. Rachet

Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma

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Reza Bayat Mokhtari, Narges Baluch, Micky Ka Hon Tsui, Sushil Kumar, Tina S. Homayouni, Karen Aitken, Bikul Das, Sylvain Baruchel, Herman Yeger

Expression of SOCS1 and the downstream targets of its putative tumor suppressor functions in prostate cancer

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Martin Chevrier, Diwakar Bobbala, Alberto Villalobos-Hernandez, Md Gulam Musawwir Khan, Sheela Ramanathan, Caroline Saucier, Gerardo Ferbeyre, Sameh Geha, Subburaj Ilangumaran

Testis specific Y-like 5: gene expression, methylation and implications for drug sensitivity in prostate carcinoma

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Senthil R. Kumar, Jeffrey N. Bryan, Magda Esebua, James Amos-Landgraf, Tanner J. May

Life tables for global surveillance of cancer survival (the CONCORD programme): data sources and methods

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Devon Spika, Finian Bannon, Audrey Bonaventure, Laura M Woods, Rhea Harewood, Helena Carreira, Michel P Coleman, Claudia Allemani

Expression of enhancer of zeste homolog 2 correlates with survival outcome in patients with metastatic breast cancer: exploratory study using primary and paired metastatic lesions

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Hitoshi Inari, Nobuyasu Suganuma, Kae Kawachi, Tatsuya Yoshida, Takashi Yamanaka, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Hirotaka Nakayama, Ayumi Yamanaka, Katsuhiko Masudo, Takashi Oshima, Tomoyuki Yokose, Yasushi Rino, Satoru Shimizu, Yohei Miyagi, Munetaka Masuda

Metallothionein 1H (MT1H) functions as a tumor suppressor in hepatocellular carcinoma through regulating Wnt/β-catenin signaling pathway

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Yulong Zheng, Lihua Jiang, Yongxian Hu, Cheng Xiao, Nong Xu, Jianying Zhou, Xinhui Zhou

In search of druggable targets for GBM amino acid metabolism

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Eduard H. Panosyan, Henry J. Lin, Jan Koster, Joseph L. Lasky III

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation

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D. J. Lundon, A. Boland, M. Prencipe, G. Hurley, A O’Neill, E. Kay, S. T. Aherne, P. Doolan, S. F. Madden, M. Clynes, C. Morrissey, J. M. Fitzpatrick, R. W. Watson

A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis

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Joyce Y. Cheng, Taylor C. Brown, Timothy D. Murtha, Adam Stenman, C. Christofer Juhlin, Catharina Larsson, James M. Healy, Manju L. Prasad, Wolfram T. Knoefel, Andreas Krieg, Ute I. Scholl, Reju Korah, Tobias Carling

Cancer-related health behaviours of young people not in education, employment or training (‘NEET’): a cross-sectional study

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Catherine H. Stewart, Philip Berry, Dunja Przulj, Charlene Treanor

Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancer-related fatigue - results of a three-armed pragmatic trial in a comprehensive cohort design

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Matthias Kröz, Marcus Reif, Augustina Glinz, Bettina Berger, Andreas Nikolaou, Roland Zerm, Benno Brinkhaus, Matthias Girke, Arndt Büssing, Christoph Gutenbrunner, Danilo Pranga, Fadime ten Brink, Anette Zander, Annette Weninger, Nina Klara, Mahmud Naghavi, Peter Klug, Andrea Küssmann, Petra Wundram, Michaele Quetz, Sarah Zastrutzki, Dorothea Friemel, Anne Kristin Meyer, Judith Schmotz, Martina Jackmuth, Suzanne Mehrtens, Sarah Zastrutzki, Christian Heckmann, Barbara Trapp, Ursula Heusser, Frederike Rettigand, Elisabeth Rieger, Astrid Didwiszus, Béatrice Gelin-Kröz, Karen Baumhöver-Wegener, Birgit Lindemann, Sonja Steffens, Ramona Beutke

A genetic variant in long non-coding RNA MALAT1 associated with survival outcome among patients with advanced lung adenocarcinoma: a survival cohort analysis

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Jian-Zhong Wang, Jing-Jun Xiang, Li-Ge Wu, Yan-Sen Bai, Zhuo-Wang Chen, Xiang-Qian Yin, Qing Wang, Wen-Hao Guo, Ying Peng, Huan Guo, Ping Xu

Access to principal treatment centres and survival rates for children and young people with cancer in Yorkshire, UK

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Lesley Fairley, Daniel P. Stark, Daniel Yeomanson, Sally E. Kinsey, Adam W. Glaser, Susan V. Picton, Linda Evans, Richard G. Feltbower

Altering calcium influx for selective destruction of breast tumor

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Han-Gang Yu, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, James Coad

miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene

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Floriana Forzati, Marco De Martino, Francesco Esposito, Romina Sepe, Simona Pellecchia, Umberto Malapelle, Gianluca Pellino, Claudio Arra, Alfredo Fusco

The C-reactive protein/albumin ratio, a validated prognostic score, predicts outcome of surgical renal cell carcinoma patients

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Shengjie Guo, Xiaobo He, Qian Chen, Guangwei Yang, Kai Yao, Pei Dong, Yunlin Ye, Dong Chen, Zhiling Zhang, Zike Qin, Zhuowei Liu, Yunfei Xue, Meng Zhang, Ruiwu Liu, Fangjian Zhou, Hui Han

Prevention of liver tumor formation in woodchucks with established hepatocellular carcinoma by treatment with cationic liposome-DNA complexes

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Jeffery Fairman, Katherine H. Liu, Stephan Menne

A phase I dose-escalation study of selumetinib in combination with docetaxel or dacarbazine in patients with advanced solid tumors

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Patricia M. LoRusso, Jeffrey R. Infante, Kevin B. Kim, Howard A. Burris III, Gregory Curt, Ugochi Emeribe, Delyth Clemett, Helen K. Tomkinson, Roger B. Cohen

Is cancer a pure growth curve or does it follow a kinetics of dynamical structural transformation?

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Maraelys Morales González, Javier Antonio González Joa, Luis Enrique Bergues Cabrales, Ana Elisa Bergues Pupo, Baruch Schneider, Suleyman Kondakci, Héctor Manuel Camué Ciria, Juan Bory Reyes, Manuel Verdecia Jarque, Miguel Angel O’Farril Mateus, Tamara Rubio González, Soraida Candida Acosta Brooks, José Luis Hernández Cáceres, Gustavo Victoriano Sierra González

miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis

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Feng Tian, Jian Chen, Shuguo Zheng, Dajiang Li, Xin Zhao, Peng Jiang, Jianwei Li, Shuguang Wang

MEIS1 inhibits clear cell renal cell carcinoma cells proliferation and in vitro invasion or migration

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Jie Zhu, Liang Cui, Axiang Xu, Xiaotao Yin, Fanglong Li, Jiangping Gao

The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice

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Agnieszka Denslow, Marta Switalska, Marcin Nowak, Magdalena Maciejewska, Stefan Chlopicki, Andrzej Marcinek, Jerzy Gebicki, Joanna Wietrzyk

Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo

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Stine S. Jensen, Stine A. Petterson, Bo Halle, Charlotte Aaberg-Jessen, Bjarne W. Kristensen

Cyproterone acetate enhances TRAIL-induced androgen-independent prostate cancer cell apoptosis via up-regulation of death receptor 5

• Open Access
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Linjie Chen, Dennis W. Wolff, Yan Xie, Ming-Fong Lin, Yaping Tu

Stereotactic prostate adaptive radiotherapy utilising kilovoltage intrafraction monitoring: the TROG 15.01 SPARK trial

• Open Access
• Study protocol

Paul Keall, Doan Trang Nguyen, Ricky O’Brien, Jeremy Booth, Peter Greer, Per Poulsen, Val Gebski, Andrew Kneebone, Jarad Martin

Redefining radiotherapy for early-stage breast cancer with single dose ablative treatment: a study protocol

• Open Access
• Study protocol

R. K. Charaghvandi, B. van Asselen, M. E. P. Philippens, H. M. Verkooijen, C. H. van Gils, P. J. van Diest, R. M. Pijnappel, M. G. G. Hobbelink, A. J. Witkamp, T. van Dalen, E. van der Wall, T. C. van Heijst, R. Koelemij, M. van Vulpen, H. J. G. D. van den Bongard

Patients with pathological stage N2 rectal cancer treated with early adjuvant chemotherapy have a lower treatment failure rate

• Open Access
• Research article

Yan-Ru Feng, Jing Jin, Hua Ren, Xin Wang, Shu-Lian Wang, Wei-Hu Wang, Yong-Wen Song, Yue-Ping Liu, Yuan Tang, Ning Li, Xin-Fan Liu, Hui Fang, Zi-Hao Yu, Ye-Xiong Li

Receiver operating characteristic analysis of prediction for gastric cancer development using serum pepsinogen and Helicobacter pylori antibody tests

• Open Access
• Research article

Chisato Hamashima, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane

Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target

• Open Access
• Research article

Cai M. Roberts, Sophia A. Shahin, Joana Loeza, Thanh H. Dellinger, John C. Williams, Carlotta A. Glackin

Radiofrequency ablation for liver metastases in patients with gastric cancer as an alternative to hepatic resection

• Open Access
• Research article

Jin Won Lee, Moon Hyung Choi, Young Joon Lee, Bandar Ali, Han Mo Yoo, Kyo Young Song, Cho Hyun Park

A survey to determine usual care after cancer treatment within the United Kingdom national health service

• Open Access
• Research article

M. Duncan, J. Deane, P. D. White, D. Ridge, R. Roylance, A. Korszun, T. Chalder, K. S. Bhui, M. A. Thaha, L. Bourke, Steph Taylor, Sandra Eldridge, Paul McCrone, Adrienne Morgan, Louise Jones, Gail Eva, John Gribben

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial

• Open Access
• Study protocol

F. M. Sullivan, Eoghan Farmer, Frances S. Mair, Shaun Treweek, Denise Kendrick, Cathy Jackson, Chris Robertson, Andrew Briggs, Colin McCowan, Laura Bedford, Ben Young, Kavita Vedhara, Stephanie Gallant, Roberta Littleford, John Robertson, Herb Sewell, Alistair Dorward, Joseph Sarvesvaran, Stuart Schembri

A multi-center phase II study and biomarker analysis of combined cetuximab and modified FOLFIRI as second-line treatment in patients with metastatic gastric cancer

• Open Access
• Research article

Xin Liu, Weijian Guo, Wen Zhang, Jiliang Yin, Jun Zhang, Xiaodong Zhu, Tianshu Liu, Zhiyu Chen, Biyun Wang, Jianhua Chang, Fangfang Lv, Xiaonan Hong, Huijie Wang, Jialei Wang, Xinmin Zhao, Xianghua Wu, Jin Li

Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo

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Alexandre Trindade, Dusan Djokovic, Joana Gigante, Liliana Mendonça, António Duarte

Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway

• Open Access
• Research article

Michele Joana Alves, Raquel Galvão Figuerêdo, Flavia Figueiredo Azevedo, Diego Alexandre Cavallaro, Nelson Inácio Pinto Neto, Joanna Darck Carola Lima, Emidio Matos-Neto, Katrin Radloff, Daniela Mendes Riccardi, Rodolfo Gonzalez Camargo, Paulo Sérgio Martins De Alcântara, José Pinhata Otoch, Miguel Luiz Batista Junior, Marília Seelaender

Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways

• Open Access
• Research article

Haiyong Wang, Jun Lu, Jian Tang, Shitu Chen, Kuifeng He, Xiaoxia Jiang, Weiqin Jiang, Lisong Teng

Functional analysis of fatty acid binding protein 7 and its effect on fatty acid of renal cell carcinoma cell lines

• Open Access
• Research article

Naohisa Takaoka, Tatsuya Takayama, Seiichiro Ozono

iCanADAPT Early protocol: randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual

• Open Access
• Study protocol

M. J. Murphy, J. M. Newby, P. Butow, L. Kirsten, K. Allison, S. Loughnan, M. A. Price, J. Shaw, H. Shepherd, J. Smith, G. Andrews

Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells

• Open Access
• Research article

Ancély F. dos Santos, Letícia F. Terra, Rosangela A. M. Wailemann, Talita C. Oliveira, Vinícius de Morais Gomes, Marcela Franco Mineiro, Flávia Carla Meotti, Alexandre Bruni-Cardoso, Maurício S. Baptista, Leticia Labriola

Erratum to: Spectrum and frequencies of BRCA1/2 mutations in Bulgarian high risk breast cancer patients

• Open Access
• Erratum

Rumyana Ivanova Dodova, Atanaska Velichkova Mitkova, Daniela Rosenova Dacheva, Lina Basam Hadjo, Alexandrina Ivanova Vlahova, Margarita Stoyanova Taushanova – Hadjieva, Spartak Stoyanov Valev, Marija Mitko Caulevska, Stanislava Dimitrova Popova, Ivan Emilov Popov, Tihomir Iliichev Dikov, Theophil Angelov Sedloev, Atanas Stefanov Ionkov, Konstanta Velinova Timcheva, Svetlana Liubomirova Christova, Ivo Marinov Kremensky, Vanio Ivanov Mitev, Radka Petrova Kaneva

Erratum to: The Women’s wellness after cancer program: a multisite, single-blinded, randomised controlled trial protocol

• Open Access
• Erratum

Debra Anderson, Charrlotte Seib, Dian Tjondronegoro, Jane Turner, Leanne Monterosso, Amanda McGuire, Janine Porter-Steele, Wei Song, Patsy Yates, Neil King, Leonie Young, Kate White, Kathryn Lee, Sonj Hall, Mei Krishnasamy, Kathy Wells, Sarah Balaam, Alexandra L. McCarthy

Objective response to mTOR inhibition in a metastatic collision tumor of the liver composed of melanoma and adenocarcinoma with TSC1 loss: a case report

• Open Access
• Case report

Munveer S. Bhangoo, Jenny Y. Zhou, Siraj M. Ali, Russell Madison, Alexa B. Schrock, Carrie Costantini

Characterizing and prognosticating chronic lymphocytic leukemia in the elderly: prospective evaluation on 455 patients treated in the United States

• Open Access
• Research article

Chadi Nabhan, Anthony Mato, Christopher R. Flowers, David L. Grinblatt, Nicole Lamanna, Mark A. Weiss, Matthew S. Davids, Arlene S. Swern, Shriya Bhushan, Kristen Sullivan, E. Dawn Flick, Pavel Kiselev, Jeff P. Sharman

Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells

• Open Access
• Research article

Yao Huang, David J. Burns, Benjamin E. Rich, Ian A. MacNeil, Abhijit Dandapat, Sajjad M. Soltani, Samantha Myhre, Brian F. Sullivan, Carol A. Lange, Leo T. Furcht, Lance G. Laing

Aprepitant for refractory cutaneous T-cell lymphoma-associated pruritus: 4 cases and a review of the literature

• Open Access
• Case report

Johanna S. Song, Marianne Tawa, Nicole G. Chau, Thomas S. Kupper, Nicole R. LeBoeuf

YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro

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• Research article

Jia Pei Lim, Sukanya Shyamasundar, Jayantha Gunaratne, Olivia Jane Scully, Ken Matsumoto, Boon Huat Bay

Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model

• Open Access
• Research article

Jo-Anne de la Mare, Tamarin Jurgens, Adrienne L. Edkins

Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells

• Open Access
• Research article

Mercè Padró, Raymond J. Louie, Brian V. Lananna, Adam J. Krieg, Luika A. Timmerman, Denise A. Chan

The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures

• Open Access
• Research article

Ravi S. Narayan, Carlos A. Fedrigo, Eelke Brands, Rogier Dik, Lukas J.A. Stalpers, Brigitta G. Baumert, Ben J. Slotman, Bart A. Westerman, Godefridus J. Peters, Peter Sminia

Erratum to: Delta-like 4/Notch signaling promotes Apc Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms

• Open Access
• Erratum

Marina Badenes, Alexandre Trindade, Hugo Pissarra, Luís Lopes-da-Costa, António Duarte

Morphological and phenotypical features of ovarian metastases in breast cancer patients

• Open Access
• Research article

Inge T. A. Peters, Merle A. van der Steen, Bertine W. Huisman, Carina G. J .M. Hilders, Vincent T. H. B. M. Smit, Alexander L. Vahrmeijer, Cornelis F. M. Sier, J. Baptist Trimbos, Peter J. K. Kuppen

Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c

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• Research article

Altay Burak Dalan, Sukru Gulluoglu, Emre Can Tuysuz, Aysegul Kuskucu, Cumhur Kaan Yaltirik, Oguz Ozturk, Ugur Ture, Omer Faruk Bayrak

Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

• Open Access
• Study protocol

Sven van den Bosch, Tim Dijkema, Martina C. Kunze-Busch, Chris H. J. Terhaard, Cornelis P. J. Raaijmakers, Patricia A. H. Doornaert, Frank J. P. Hoebers, Marije R. Vergeer, Bas Kreike, Oda B. Wijers, Wim J. G. Oyen, Johannes H. A. M. Kaanders

Investigating young women’s motivations to engage in early mammography screening in Switzerland: results of a cross-sectional study

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Nanon H. M. Labrie, Ramona Ludolph, Peter J. Schulz

Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging

• Open Access
• Research article

José Angel García-Saenz, Patricia Ayllón, Marion Laig, Daniel Acosta-Eyzaguirre, Marta García-Esquinas, Myriam Montes, Julián Sanz, Miguel Barquín, Fernando Moreno, Vanesa Garcia-Barberan, Eduardo Díaz-Rubio, Trinidad Caldes, Atocha Romero

Prospective phase II trial of everolimus in PIK3CA amplification/mutation and/or PTEN loss patients with advanced solid tumors refractory to standard therapy

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• Research article

Seung Tae Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Won Ki Kang, Ho Yeong Lim

Midkine is a potential novel marker for malignant mesothelioma with different prognostic and diagnostic values from mesothelin

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Guntulu Ak, Yuji Tada, Hideaki Shimada, Selma Metintas, Masaaki Ito, Kenzo Hiroshima, Masatoshi Tagawa, Muzaffer Metintas

A systematic review of prognostic factors at the end of life for people with a hematological malignancy

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Elise Button, Raymond Javan Chan, Shirley Chambers, Jason Butler, Patsy Yates

Characteristics of early-onset hematotoxicity of sunitinib in Japanese patients with renal cell carcinoma

• Open Access
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Renpei Kato, Yoichiro Kato, Tomohiko Matsuura, Mitsugu Kanehira, Ryo Takata, Wataru Obara

u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression

• Open Access
• Research article

S Ciavarella, A Laurenzana, S De Summa, B Pilato, A Chillà, R Lacalamita, C Minoia, F Margheri, A Iacobazzi, A Rana, F Merchionne, G Fibbi, M Del Rosso, A Guarini, S Tommasi, S Serratì

Innovative substance 2250 as a highly promising anti-neoplastic agent in malignant pancreatic carcinoma - in vitro and in vivo

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• Research article

M. Buchholz, B. Majchrzak-Stiller, S. Hahn, D. Vangala, R. W. Pfirrmann, W. Uhl, C. Braumann, A. M. Chromik

Stage IVb thymic carcinoma: patients with lymph node metastases have better prognoses than those with hematogenous metastases

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Yu Yang, Xing-Wen Fan, Hong-Bing Wang, Yin Xu, Dou-Dou Li, Kai-Liang Wu

Design of a randomized controlled trial of physical training and cancer (Phys-Can) – the impact of exercise intensity on cancer related fatigue, quality of life and disease outcome

• Open Access
• Study protocol

Sveinung Berntsen, Neil K Aaronson, Laurien Buffart, Sussanne Börjeson, Ingrid Demmelmaier, Maria Hellbom, Pernille Hojman, Helena Igelström, Birgitta Johansson, Ronnie Pingel, Truls Raastad, Galina Velikova, Pernilla Åsenlöf, Karin Nordin

DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour biopsies

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Diana Cervantes-Madrid, Yvonne Wettergren, Peter Falk, Kent Lundholm, Annika G. Asting

A possible association of baseline serum IL-17A concentrations with progression-free survival of metastatic colorectal cancer patients treated with a bevacizumab-based regimen

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• Research article

Emilie Lereclus, Mira Tout, Alban Girault, Nadine Baroukh, Morgane Caulet, Christophe Borg, Olivier Bouché, David Ternant, Gilles Paintaud, Thierry Lecomte, William Raoul

Malignant acrospiroma: a case report in the era of next generation sequencing

• Open Access
• Case report

Maria Diab, Ali Gabali, Muaiad Kittaneh

ABCG2 is a potential prognostic marker of overall survival in patients with clear cell renal cell carcinoma

• Open Access
• Research article

Haofei Wang, Fangxiu Luo, Zhe Zhu, Zhaoping Xu, Xin Huang, Renyi Ma, Hongchao He, Yu Zhu, Kun Shao, Juping Zhao

Case management to increase quality of life after cancer treatment: a randomized controlled trial

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Nathalie Scherz, Irène Bachmann-Mettler, Corinne Chmiel, Oliver Senn, Nathalie Boss, Katarina Bardheci, Thomas Rosemann

Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion

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Bethan A. Frugtniet, Tracey A. Martin, Lijian Zhang, Wen G. Jiang

Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review

• Open Access
• Case report

Varun V. Varadarajan, Elizabeth K. Pace, Vatsal Patel, Raja Sawhney, Robert J. Amdur, Peter T. Dziegielewski

Can we use gonadotropin plasma concentration as surrogate marker for BMI-related incomplete estrogen suppression in breast cancer patients receiving anastrozole?

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• Research article

A. Oberguggenberger, V. Meraner, M. Sztankay, B. Beer, G. Weigel, H. Oberacher, G. Kemmler, T. Czech, B. Holzner, L. Wildt, B. Sperner-Unterweger, M. Daniaux, M. Hubalek

Negative lymph node count is an independent prognostic factor for patients with rectal cancer who received preoperative radiotherapy

• Open Access
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Xinxing Li, Hao Lu, Kai Xu, Haolu Wang, Xiaowen Liang, Zhiqian Hu

Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer

• Open Access
• Research article

Tyler McInnes, Donghui Zou, Dasari S. Rao, Francesca M. Munro, Vicky L. Phillips, John L. McCall, Michael A. Black, Anthony E. Reeve, Parry J. Guilford

Protocol of the PANCALYZE trial: a multicenter, prospective study investigating the tumor biomarkers CXCR4, SMAD4, SOX9 and IFIT3 in patients with resected pancreatic adenocarcinoma to predict the pattern of recurrence of the disease

• Open Access
• Study protocol

Felix C. Popp, Marie Christine Popp, Yue Zhao, Christopher Betzler, Siegfried Kropf, Benjamin Garlipp, Christoph Benckert, Thomas Kalinski, Hans Lippert, Christiane J. Bruns

Amplification and up-regulation of MIR30D was associated with disease progression of cervical squamous cell carcinomas

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You Zhou, Yinghua Hao, Yuxia Li, Ruizhen Li, Ruifang Wu, Shubin Wang, Zhengyu Fang

Distribution of Ki-67 values within HER2 & ER/PgR expression variants of ductal breast cancers as a potential link between IHC features and breast cancer biology

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Sven Kurbel, Branko Dmitrović, Ksenija Marjanović, Damir Vrbanec, Antonije Juretić

Anti-tumor effects of everolimus and metformin are complementary and glucose-dependent in breast cancer cells

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Gerke Ariaans, Mathilde Jalving, Emma Geertruida Elisabeth de Vries, Steven de Jong

Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism

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Marcus W. Stepp, Mark A. Doll, David J. Samuelson, Mary Ann G. Sanders, J. Christopher States, David W. Hein

Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device

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Akira Yamauchi, Masahiro Yamamura, Naoki Katase, Masumi Itadani, Naoko Okada, Kayoko Kobiki, Masafumi Nakamura, Yoshiyuki Yamaguchi, Futoshi Kuribayashi

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

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C. P. Baburajeev, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Daniel J. Mason, Julian E. Fuchs, Andreas Bender, Uri Barash, Israel Vlodavsky, Basappa, Kanchugarakoppal S. Rangappa

Aberrant expression of ALK and EZH2 in Merkel cell carcinoma

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Tuukka Veija, Virve Koljonen, Tom Bohling, Mia Kero, Sakari Knuutila, Virinder Kaur Sarhadi

Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder

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Makito Miyake, Yosuke Morizawa, Shunta Hori, Nagaaki Marugami, Keiji Shimada, Daisuke Gotoh, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Nobumichi Tanaka, Kiyohide Fujimoto

The IGCA staging system is more accurate than AJCC7 system in stratifying survival of patients with gastric cancer in stage III

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Ping Shu, Jing Qin, Kuntang Shen, Weidong Chen, Fenglin Liu, Yong Fang, Xuefei Wang, Hongshan Wang, Zhenbin Shen, Yihong Sun, Xinyu Qin

The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies

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Joanna Trubicka, Tomasz Żemojtel, Jochen Hecht, Katarzyna Falana, Dorota Piekutowska- Abramczuk, Rafał Płoski, Marta Perek-Polnik, Monika Drogosiewicz, Wiesława Grajkowska, Elżbieta Ciara, Elżbieta Moszczyńska, Bożenna Dembowska-Bagińska, Danuta Perek, Krystyna H. Chrzanowska, Małgorzata Krajewska-Walasek, Maria Łastowska

Prognostic value of transforming growth factor-beta in patients with colorectal cancer who undergo surgery: a meta-analysis

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• Research article

Xin-lin Chen, Zhuo-qun Chen, Shui-lian Zhu, Tian-wen Liu, Yi Wen, Yi-sheng Su, Xu-jie Xi, Yue Hu, Lei Lian, Feng-bin Liu

Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue

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• Research article

Bojana Jovanović, Quanhu Sheng, Robert S. Seitz, Kasey D. Lawrence, Stephan W. Morris, Lance R. Thomas, David R. Hout, Brock L. Schweitzer, Yan Guo, Jennifer A. Pietenpol, Brian D. Lehmann

Timing of chemotherapy-induced neutropenia predicts prognosis in metastatic colon cancer patients: a retrospective study in mFOLFOX6 -treated patients

• Open Access
• Research article

Yang Chen, YanRong Wang, Yan Shi, GuangHai Dai

The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902)

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• Research article

Goro Nakayama, Kiyoshi Ishigure, Hiroyuki Yokoyama, Keisuke Uehara, Hiroshi Kojima, Akiharu Ishiyama, Naomi Hayashi, Nao Takano, Norifumi Hattori, Daisuke Kobayashi, Chie Tanaka, Masamichi Hayashi, Mitsuro Kanda, Suguru Yamada, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Tsutomu Fujii, Kenta Murotani, Yuichi Ando, Yasuhiro Kodera

Metastatic polyp of the gallbladder from renal cell carcinoma

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Bor-Uei Shyr, Shih-Chin Chen, Yi-Ming Shyr, Rheun-Chuan Lee, Shin-E Wang

Central nervous system progression in advanced non–small cell lung cancer patients with EGFR mutations in response to first-line treatment with two EGFR-TKIs, gefitinib and erlotinib: a comparative study

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Meng-Xia Li, Hao He, Zhi-Hua Ruan, Yu-Xi Zhu, Rong-Qing Li, Xiao He, Bao-Hua Lan, Zhi-Min Zhang, Guo-Dong Liu, Hua-Liang Xiao, Yan Wu, Bo Zhu, Ge Wang, Zhen-Zhou Yang

Glucose and lipoprotein biomarkers and breast cancer severity using data from the Swedish AMORIS cohort

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Jennifer C Melvin, Hans Garmo, Lars Holmberg, Niklas Hammar, Göran Walldius, Ingmar Jungner, Mats Lambe, Mieke Van Hemelrijck

A prospective comparison of UroVysion FISH and urine cytology in bladder cancer detection

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Hugh J. Lavery, Boriana Zaharieva, Andrew McFaddin, Nyla Heerema, Kamal S. Pohar

Long non-coding RNA XIST regulates PTEN expression by sponging miR-181a and promotes hepatocellular carcinoma progression

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Shuzhen Chang, Binhe Chen, Xiaoyan Wang, Keqin Wu, Yuqiu Sun

Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer

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Tristan Lerbs, Savita Bisht, Sebastian Schölch, Mathieu Pecqueux, Glen Kristiansen, Martin Schneider, Bianca T. Hofmann, Thilo Welsch, Christoph Reissfelder, Nuh N. Rahbari, Johannes Fritzmann, Peter Brossart, Jürgen Weitz, Georg Feldmann, Christoph Kahlert

Myoepithelial carcinoma with RB1 mutation: remarkable chemosensitivity to carcinoma of unknown origin therapy

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• Case report

Timothy M. Hoggard, Evita Henderson-Jackson, Marilyn M. Bui, Jamie Caracciolo, Jamie K. Teer, Sean Yoder, Odion Binitie, Ricardo J. Gonzalez, Andrew S. Brohl, Damon R. Reed

Sidedness is prognostic in locoregional colon cancer: an analysis of 9509 Australian patients

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Daniel Brungs, Morteza Aghmesheh, Paul de Souza, Weng Ng, Wei Chua, Martin Carolan, Philip Clingan, Emma Healey, June Rose, Tameika Tubaro, Marie Ranson

Emerging role of mutations in epigenetic regulators including MLL2 derived from The Cancer Genome Atlas for cervical cancer

• Open Access
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Xia Li

A multicentre randomised controlled trial to evaluate the efficacy, morbidity and functional outcome of endoscopic transanal proctectomy versus laparoscopic proctectomy for low-lying rectal cancer (ETAP-GRECCAR 11 TRIAL): rationale and design

• Open Access
• Study protocol

Bernard Lelong, Cécile de Chaisemartin, Helene Meillat, Sandra Cournier, Jean Marie Boher, Dominique Genre, Mehdi Karoui, Jean Jacques Tuech, Jean Robert Delpero

Optimal treatment and prognostic factors for esthesioneuroblastoma: retrospective analysis of 187 Chinese patients

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Le Xiong, Xiao-Li Zeng, Chang-Kuo Guo, An-Wen Liu, Long Huang

Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73

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• Research article

Xu Yang, Shimin Pei, Huanan Wang, Yipeng Jin, Fang Yu, Bin Zhou, Hong Zhang, Di Zhang, Degui Lin

Cost-effectiveness of response evaluation after chemoradiation in patients with advanced oropharyngeal cancer using 18F–FDG-PET-CT and/or diffusion-weighted MRI

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Marjolein JE Greuter, Charlotte S Schouten, Jonas A Castelijns, Pim de Graaf, Emile FI Comans, Otto S Hoekstra, Remco de Bree, Veerle MH Coupé

Infections and cancer: the “fifty shades of immunity” hypothesis

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• Debate

Camille Jacqueline, Aurélie Tasiemski, Gabriele Sorci, Beata Ujvari, Fatima Maachi, Dorothée Missé, François Renaud, Paul Ewald, Frédéric Thomas, Benjamin Roche

Gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol

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• Study protocol

Charlotte M.C. Oude Ophuis, Lisa B. Koppert, Cécile de Monyé, Carolien H.M. van Deurzen, Senada Koljenović, Alexander C.J. van Akkooi, Cornelis Verhoef, Dirk J. Grünhagen

Weight change during chemotherapy in breast cancer patients: a meta-analysis

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• Research article

M.M.G.A. van den Berg, R.M. Winkels, J.Th.C.M. de Kruif, H.W.M van Laarhoven, M. Visser, J.H.M. de Vries, Y.C. de Vries, E. Kampman

Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

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• Research article

Melanie Spitzwieser, Elisabeth Entfellner, Bettina Werner, Walter Pulverer, Georg Pfeiler, Stefan Hacker, Margit Cichna-Markl

Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression

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• Research article

Marjolaine Ngollo, Andre Lebert, Marine Daures, Gaelle Judes, Khaldoun Rifai, Lucas Dubois, Jean-Louis Kemeny, Frederique Penault-Llorca, Yves-Jean Bignon, Laurent Guy, Dominique Bernard-Gallon

Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials

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• Research article

Mairéad Geraldine McNamara, John Bridgewater, Andre Lopes, Harpreet Wasan, David Malka, Lars Henrik Jensen, Takuji Okusaka, Jennifer J. Knox, Dorothea Wagner, David Cunningham, Jenny Shannon, David Goldstein, Markus Moehler, Tanios Bekaii-Saab, Juan W. Valle

MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study

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• Research article

Yasushi Horimasu, Nobuhisa Ishikawa, Sonosuke Tanaka, Chihiro Hirano, Hiroshi Iwamoto, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori, Nobuoki Kohno

Effect of individualized communication skills training on physicians’ discussion of clinical trials in oncology: results from a randomized controlled trial

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Alexander Wuensch, Tanja Goelz, Gabriele Ihorst, Darcey D. Terris, Hartmut Bertz, Juergen Bengel, Michael Wirsching, Kurt Fritzsche

Adjuvant treatment recommendations for patients with ER-positive/HER2-negative early breast cancer by Swiss tumor boards using the 21-gene recurrence score (SAKK 26/10)

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• Research article

Bernhard C. Pestalozzi, Christoph Tausch, Konstantin J. Dedes, Christoph Rochlitz, Stefan Zimmermann, Roger von Moos, Ralph Winterhalder, Thomas Ruhstaller, Andreas Mueller, Katharina Buser, Markus Borner, Urban Novak, Catrina Uhlmann Nussbaum, Bettina Seifert, Martin Bigler, Vincent Bize, Simona Berardi Vilei, Christoph Rageth, Stefan Aebi

Alpha–fetoprotein elevation in NUT midline carcinoma: a case report

• Open Access
• Case report

Lorenzo D’Ambrosio, Erica Palesandro, Marina Moretti, Giuseppe Pelosi, Alessandra Fabbri, Fabrizio Carnevale Schianca, Massimo Aglietta, Giovanni Grignani

A prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer

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• Research article

Fei Zhao, Yue Zhou, Peng-Fei Ge, Chen-Jun Huang, Yue Yu, Jun Li, Yun-Gang Sun, Yang-Chun Meng, Jian-Xia Xu, Ting Jiang, Zhi-Xuan Zhang, Jin-Peng Sun, Wei Wang

Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer

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Xiangbin Xing, Weibin Cai, Sanmei Ma, Yongfei Wang, Huijuan Shi, Ming Li, Jinxia Jiao, Yang Yang, Longshan Liu, Xiangliang Zhang, Minhu Chen

Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)

• Open Access
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Ting Zhou, Jianhua Zhan, Wenfeng Fang, Yuanyuan Zhao, Yunpeng Yang, Xue Hou, Zhonghan Zhang, Xiaobo He, Yaxiong Zhang, Yan Huang, Li Zhang

Overview of cancer incidence and mortality among people living with HIV/AIDS in British Columbia, Canada: Implications for HAART use and NADM development

• Open Access
• Research article

Connie G. Chiu, Danielle Smith, Kate A. Salters, Wendy Zhang, Steve Kanters, David Milan, Julio S.G. Montaner, Andy Coldman, Robert S. Hogg, Sam M. Wiseman

Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis

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Jing Yu, Lian Liu, Yue Zhang, Jia Wei, Fan Yang

Appraising the holistic value of Lenvatinib for radio-iodine refractory differentiated thyroid cancer: A multi-country study applying pragmatic MCDA

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Monika Wagner, Hanane Khoury, Liga Bennetts, Patrizia Berto, Jenifer Ehreth, Xavier Badia, Mireille Goetghebeur

Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

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Marie K. Kirby, Ryne C. Ramaker, Brian S. Roberts, Brittany N. Lasseigne, David S. Gunther, Todd C. Burwell, Nicholas S. Davis, Zulfiqar G. Gulzar, Devin M. Absher, Sara J. Cooper, James D. Brooks, Richard M. Myers

Evaluation of the association between quantitative mammographic density and breast cancer occurred in different quadrants

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Siwa Chan, Jeon-Hor Chen, Shunshan Li, Rita Chang, Darh-Cherng Yeh, Ruey-Feng Chang, Lee-Ren Yeh, Jessica Kwong, Min-Ying Su

Prognostic value of pretreatment standardized uptake value of F-18-fluorodeoxyglucose PET in patients with gastric cancer: a meta-analysis

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Zhonghua Wu, Junhua Zhao, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Bin Ma, Zhenning Wang

The treatment of primary mediastinal large B-cell lymphoma: a two decades monocentric experience with 98 patients

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Alessandro Broccoli, Beatrice Casadei, Vittorio Stefoni, Cinzia Pellegrini, Federica Quirini, Lorenzo Tonialini, Alice Morigi, Miriam Marangon, Lisa Argnani, Pier Luigi Zinzani

Arsenic treatment increase Aurora-A overexpression through E2F1 activation in bladder cells

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Yu-Ting Kao, Chin-Han Wu, Shan-Ying Wu, Sheng-Hui Lan, Hsiao-Sheng Liu, Ya-Shih Tseng

Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients

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Thomas Urup, Line Mærsk Staunstrup, Signe Regner Michaelsen, Kristoffer Vitting-Seerup, Marc Bennedbæk, Anders Toft, Lars Rønn Olsen, Lars Jønson, Shohreh Issazadeh-Navikas, Helle Broholm, Petra Hamerlik, Hans Skovgaard Poulsen, Ulrik Lassen

Contrast-enhanced US with Perfluorobutane(Sonazoid) used as a surveillance test for Hepatocellular Carcinoma (HCC) in Cirrhosis (SCAN): an exploratory cross-sectional study for a diagnostic trial

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• Study protocol

Ji Hoon Park, Mi-Suk Park, So Jung Lee, Woo Kyoung Jeong, Jae Young Lee, Min Jung Park, Kyunghwa Han, Chung Mo Nam, Seong Ho Park, Kyoung Ho Lee

Prognostic significance of TRAIL-R3 and CCR-2 expression in tumor epithelial cells of patients with early breast cancer

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Vivian Labovsky, Leandro Marcelo Martinez, Kevin Mauro Davies, María de Luján Calcagno, Hernán García-Rivello, Alejandra Wernicke, Leonardo Feldman, Ayelén Matas, María Belén Giorello, Francisco Raúl Borzone, Hosoon Choi, Scott C. Howard, Norma Alejandra Chasseing

Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A

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Masato Chiba, Yosuke Togashi, Eri Bannno, Yoshihisa Kobayashi, Yu Nakamura, Hidetoshi Hayashi, Masato Terashima, Marco A. De Velasco, Kazuko Sakai, Yoshihiko Fujita, Tetsuya Mitsudomi, Kazuto Nishio

Imatinib treatment of poor prognosis mesenchymal-type primary colon cancer: a proof-of-concept study in the preoperative window period (ImPACCT)

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• Study protocol

I. Ubink, H. J. Bloemendal, S. G. Elias, M. A. Brink, M. P. Schwartz, Y. C. W. Holierhoek, P. M. Verheijen, A. W. Boerman, R. H. J. Mathijssen, W. W. J. de Leng, R. A. de Weger, W. M. U. van Grevenstein, M. Koopman, M. P. Lolkema, O. Kranenburg, I. H. M. Borel Rinkes

Prevalence and prognostic implications of psychological distress in patients with gastric cancer

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Gun Min Kim, Seung Jun Kim, Su Kyung Song, Hye Ryun Kim, Beo Deul Kang, Sung Hoon Noh, Hyun Cheol Chung, Kyung Ran Kim, Sun Young Rha

A protocol for a cluster-randomized controlled trial of a self-help psycho-education programme to reduce diagnosis delay in women with breast cancer symptoms in Indonesia

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• Study protocol

Hari Setyowibowo, Marit Sijbrandij, Aulia Iskandarsyah, Joke A. M. Hunfeld, Sawitri S. Sadarjoen, Dharmayanti F. Badudu, Drajat R. Suardi, Jan Passchier

The prognostic value of the preoperative c-reactive protein/albumin ratio in ovarian cancer

• Open Access
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Yubo Liu, Shengfu Chen, Chengyu Zheng, Miao Ding, Lan Zhang, Liangan Wang, Meiqing Xie, Jianhua Zhou

Regular recreational physical activity and risk of head and neck cancer

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Chen-Lin Lin, Wei-Ting Lee, Chun-Yen Ou, Jenn-Ren Hsiao, Cheng-Chih Huang, Jehn-Shyun Huang, Tung-Yiu Wong, Ken-Chung Chen, Sen-Tien Tsai, Sheen-Yie Fang, Tze-Ta Huang, Jiunn-Liang Wu, Yuan-Hua Wu, Wei-Ting Hsueh, Chia-Jui Yen, Yu-Hsuan Lai, Hsiao-Chen Liao, Shang-Yin Wu, Ming-Wei Yang, Forn-Chia Lin, Jang-Yang Chang, Yi-Hui Wang, Ya-Ling Weng, Han-Chien Yang, Yu-Shan Chen, Jeffrey S. Chang

Is adjuvant chemotherapy necessary in pT1N1 gastric cancer?

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Hyun Beak Shin, Ji Yeong An, Seung Hyoung Lee, Yoon Young Choi, Jong Won Kim, Soo Sang Sohn, Sung Hoon Noh

The safety and efficacy of percutaneous intraductal radiofrequency ablation in unresectable malignant biliary obstruction: A single-institution experience

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Wei Cui, Wenzhe Fan, Mingjian Lu, Yingqiang Zhang, Wang Yao, Jiaping Li, Yu Wang

Observation of Zn-photoprotoporphyrin red Autofluorescence in human bronchial cancer using color-fluorescence endoscopy

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Yoshinobu Ohsaki, Takaaki Sasaki, Satoshi Endo, Masahiro Kitada, Shunsuke Okumura, Noriko Hirai, Yoshihiro Kazebayashi, Eri Toyoshima, Yasushi Yamamoto, Kaneyoshi Takeyama, Susumu Nakajima, Isao Sakata

Effect of genetic variants and traits related to glucose metabolism and their interaction with obesity on breast and colorectal cancer risk among postmenopausal women

• Open Access
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Su Yon Jung, Eric M. Sobel, Jeanette C. Papp, Zuo-Feng Zhang

A mobile application of breast cancer e-support program versus routine Care in the treatment of Chinese women with breast cancer undergoing chemotherapy: study protocol for a randomized controlled trial

• Open Access
• Study protocol

Jiemin Zhu, Lyn Ebert, Xiangyu Liu, Sally Wai-Chi Chan

MiR-23b controls ALDH1A1 expression in cervical cancer stem cells

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Weiwen Wang, Yang Li, Na Liu, Yu Gao, Long Li

Distinct immunophenotypes and prognostic factors in renal cell carcinoma with sarcomatoid differentiation: a systematic study of 19 immunohistochemical markers in 42 cases

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Wenjuan Yu, Yuewei Wang, Yanxia Jiang, Wei Zhang, Yujun Li

Potential of extravasated platelet aggregation as a surrogate marker for overall survival in patients with advanced gastric cancer treated with preoperative docetaxel, cisplatin and S-1: a retrospective observational study

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Hiroto Saito, Sachio Fushida, Tomoharu Miyashita, Katsunobu Oyama, Takahisa Yamaguchi, Tomoya Tsukada, Jun Kinoshita, Hidehiro Tajima, Itasu Ninomiya, Tetsuo Ohta

Prognosis and treatment of non-metastatic primary and secondary breast angiosarcoma: a comparative study

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Ming Yin, Wenge Wang, Joseph J. Drabick, Harvey A. Harold

Influence of presence/absence of thyroid gland on the cutoff value for thyroglobulin in lymph-node aspiration to detect metastatic papillary thyroid carcinoma

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Huan Zhao, Yong Wang, Min-jie Wang, Zhi-hui Zhang, Hai-rui Wang, Bing Zhang, Hui-qin Guo

Long-term results of early adjuvant concurrent chemoradiotherapy for high-risk, early stage uterine cervical cancer patients after radical hysterectomy

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Sang-Won Kim, Mison Chun, Hee-Sug Ryu, Suk-Joon Chang, Tae Wook Kong, Young-Taek Oh, Seung Hee Kang

A randomized controlled trial of physical activity, dietary habit, and distress management with the Leadership and Coaching for Health (LEACH) program for disease-free cancer survivors

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Young Ho Yun, Young Ae Kim, Myung Kyung Lee, Jin Ah Sim, Byung-Ho Nam, Sohee Kim, Eun Sook Lee, Dong-Young Noh, Jae-Young Lim, Sung Kim, Si-Young Kim, Chi-Heum Cho, Kyung Hae Jung, Mison Chun, Soon Nam Lee, Kyong Hwa Park, Sohee Park

Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L)

• Open Access
• Study protocol

Stuart A. Taylor, Sue Mallett, Anne Miles, Sandy Beare, Gauraang Bhatnagar, John Bridgewater, Rob Glynne-Jones, Vicky Goh, Ashley M. Groves, Sam M. Janes, Dow Mu Koh, Steve Morris, Alison Morton, Neal Navani, Alf Oliver, Anwar R. Padhani, Shonit Punwani, Andrea G. Rockall, Steve Halligan

Diagnostic value of endoscopic appearance during ductoscopy in patients with pathological nipple discharge

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Ye Han, Jianyi Li, Sijia Han, Shi Jia, Yang Zhang, Wenhai Zhang

A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells

• Open Access
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Jiyoun Yeo, Erin L. Crawford, Xiaolu Zhang, Sadik Khuder, Tian Chen, Albert Levin, Thomas M. Blomquist, James C. Willey

Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study

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Kota Nakamura, Motoyasu Kato, Takehito Shukuya, Keita Mori, Yasuhito Sekimoto, Hiroaki Ihara, Ryota Kanemaru, Ryo Ko, Rina Shibayama, Ken Tajima, Ryo Koyama, Naoko Shimada, Osamu Nagashima, Fumiyuki Takahashi, Shinichi Sasaki, Kazuhisa Takahashi

Immunohistochemical evaluation of epithelial ovarian carcinomas identifies three different expression patterns of the MX35 antigen, NaPi2b

• Open Access
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Kristina Levan, Matin Mehryar, Constantina Mateoiu, Per Albertsson, Tom Bäck, Karin Sundfeldt

Hepatitis B virus infection and active replication promote the formation of vascular invasion in hepatocellular carcinoma

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Xubiao Wei, Nan Li, Shanshan Li, Jie Shi, Weixing Guo, Yaxin Zheng, Shuqun Cheng

MicroRNA-30a regulates cell proliferation and tumor growth of colorectal cancer by targeting CD73

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Minghao Xie, Huabo Qin, Qianxin Luo, Qunsheng Huang, Xiaosheng He, Zihuan Yang, Ping Lan, Lei Lian

The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients

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Kenneth M. K. Mark, Frederick S. Varn, Matthew H. Ung, Feng Qian, Chao Cheng

The repressive effect of miR-148a on Wnt/β-catenin signaling involved in Glabridin-induced anti-angiogenesis in human breast cancer cells

• Open Access
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Juan Mu, Dongmei Zhu, Zhaoxia Shen, Shilong Ning, Yun Liu, Juan Chen, Yuan Li, Zhong Li

Adjuvant radiotherapy after radical cystectomy for patients with muscle invasive bladder cancer: a phase II trial

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• Study protocol

Valérie Fonteyne, Piet Dirix, Sara Junius, Elke Rammant, Piet Ost, Gert De Meerleer, Martijn Swimberghe, Karel Decaestecker

Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways

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Kengo Shimazu, Yuji Tada, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Hideaki Shimada, Kenzo Hiroshima, Takao Namiki, Koichiro Tatsumi, Masatoshi Tagawa

Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas

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Birgitta Lehtinen, Annina Raita, Juha Kesseli, Matti Annala, Kristiina Nordfors, Olli Yli-Harja, Wei Zhang, Tapio Visakorpi, Matti Nykter, Hannu Haapasalo, Kirsi J. Granberg

KRAS mutation analysis of single circulating tumor cells from patients with metastatic colorectal cancer

• Open Access
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Yuurin Kondo, Kazuhiko Hayashi, Kazuyuki Kawakami, Yukari Miwa, Hiroshi Hayashi, Masakazu Yamamoto

Ethnic differences in colon cancer care in the Netherlands: a nationwide registry-based study

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M. Lamkaddem, M. A. G. Elferink, M. C. Seeleman, E. Dekker, C. J. A. Punt, O. Visser, M. L. Essink-Bot

Evaluation for inherited and acquired prothrombotic defects predisposing to symptomatic thromboembolism in children with acute lymphoblastic leukemia: a protocol for a prospective, observational, cohort study

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• Study protocol

Uma H. Athale, Caroline Laverdiere, Trishana Nayiager, Yves-Line Delva, Gary Foster, Lehana Thabane, Anthony KC Chan

Efficacy and safety of rebamipide liquid for chemoradiotherapy-induced oral mucositis in patients with head and neck cancer: a multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II study

• Open Access
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T. Yokota, T. Ogawa, S. Takahashi, K. Okami, T. Fujii, K. Tanaka, S. Iwae, I. Ota, T. Ueda, N. Monden, K. Matsuura, H. Kojima, S. Ueda, K. Sasaki, Y. Fujimoto, Y. Hasegawa, T. Beppu, H. Nishimori, S. Hirano, Y. Naka, Y. Matsushima, M. Fujii, M. Tahara

Interval breast cancer characteristics before, during and after the transition from screen-film to full-field digital screening mammography

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Rob M. G. van Bommel, Roy Weber, Adri C. Voogd, Joost Nederend, Marieke W. J. Louwman, Dick Venderink, Luc J. A. Strobbe, Matthieu J. C. Rutten, Menno L. Plaisier, Paul N. Lohle, Marianne J. H. Hooijen, Vivianne C.G. Tjan-Heijnen, Lucien E. M. Duijm

Gamma-glutamyltransferase activity in exosomes as a potential marker for prostate cancer

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Kyojiro Kawakami, Yasunori Fujita, Yoko Matsuda, Tomio Arai, Kengo Horie, Koji Kameyama, Taku Kato, Koichi Masunaga, Yutaka Kasuya, Masashi Tanaka, Kosuke Mizutani, Takashi Deguchi, Masafumi Ito

Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma

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Shuang Ye, Tiancong He, Shanhui Liang, Xiaojun Chen, Xiaohua Wu, Huijuan Yang, Libing Xiang

Electronic patient self-Reporting of Adverse-events: Patient Information and aDvice (eRAPID): a randomised controlled trial in systemic cancer treatment

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Kate Absolom, Patricia Holch, Lorraine Warrington, Faye Samy, Claire Hulme, Jenny Hewison, Carolyn Morris, Leon Bamforth, Mark Conner, Julia Brown, Galina Velikova

Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells

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Susanne Schüler-Toprak, Christoph Moehle, Maciej Skrzypczak, Olaf Ortmann, Oliver Treeck

Presence of human papillomavirus DNA in breast cancer: a Spanish case-control study

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Silvia Delgado-García, Juan-Carlos Martínez-Escoriza, Alfonso Alba, Tina-Aurora Martín-Bayón, Hortensia Ballester-Galiana, Gloria Peiró, Pablo Caballero, Jose Ponce-Lorenzo

Impact of lymphovascular invasion on lymph node metastasis for patients undergoing radical prostatectomy with negative resection margin

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Yong Jin Kang, Hyun-Soo Kim, Won Sik Jang, Jong Kyou Kwon, Cheol Yong Yoon, Joo Yong Lee, Kang Su Cho, Won Sik Ham, Young Deuk Choi

Transhepatic arterial infusion chemotherapy using a combination of miriplatin and CDDP powder versus miriplatin alone in the treatment of hepatocellular carcinoma: a randomized controlled trial

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Kenya Kamimura, Takeshi Suda, Takeshi Yokoo, Hiroteru Kamimura, Tsutomu Kanefuji, Atsunori Tsuchiya, Masaaki Takamura, Hirokazu Kawai, Nobuo Waguri, Satoshi Yamagiwa, Shuji Terai

Metastatic non-muscle invasive bladder cancer with meningeal carcinomatosis: case report of an unexpected response

• Open Access
• Case report

Diego Teyssonneau, Amaury Daste, Vincent Dousset, Jean-Luc Hoepffner, Alain Ravaud, Marine Gross-Goupil

MDA-MET-conditioned-medium augments the chemoattractant-dependent migration of MDA-MET cells towards hFOB-conditioned medium and increases collagenase activity

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Karis Chin-Quee, Henry J. Donahue

Clinical benefit of adding oxaliplatin to standard neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a meta-analysis

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Francesca De Felice, Ilaria Benevento, Anna Lisa Magnante, Daniela Musio, Nadia Bulzonetti, Rossella Caiazzo, Vincenzo Tombolini

A French national breast and thyroid cancer screening programme for survivors of childhood, adolescent and young adult (CAYA) cancers - DeNaCaPST programme

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Charlotte Demoor-Goldschmidt, Delphine Drui, Isabelle Doutriaux, Gérard Michel, Pascal Auquier, Agnès Dumas, Claire Berger, Valérie Bernier, Sandrine Bohrer, Pierre-Yves Bondiau, Bruno Filhon, Brice Fresneau, Claire Freycon, Dinu Stefan, Sylvie Helfre, Angela Jackson, Christine Kerr, Anne Laprie, Julie Leseur, Marc-André Mahé, Caroline Oudot, Claire Pluchard, Stéphanie Proust, Hélène Sudour-Bonnange, Céline Vigneron, Nathalie Lassau, Martin Schlumberger, Cécile Faure Conter, Florent de Vathaire

Paraneoplastic acral vascular syndrome in a patient with metastatic melanoma under immune checkpoint blockade

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• Case report

Thilo Gambichler, Stefanie Strutzmann, Andrea Tannapfel, Laura Susok

Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation

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Christine Lonjou, Francesca Damiola, Monika Moissonnier, Geoffroy Durand, Irina Malakhova, Vladimir Masyakin, Florence Le Calvez-Kelm, Elisabeth Cardis, Graham Byrnes, Ausrele Kesminiene, Fabienne Lesueur

The role of BRCA1-IRIS in the development and progression of triple negative breast cancers in Egypt: possible link to disease early lesion

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Danielle Bogan, Lucio Meile, Ahmed El Bastawisy, Hend F. Yousef, Abdel-Rahman N. Zekri, Abeer A. Bahnassy, Wael M. ElShamy

Characterization of genetic aberrations in a single case of metastatic thymic adenocarcinoma

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Yeonghun Lee, Sehhoon Park, Se-Hoon Lee, Hyunju Lee

Retrospective study of nonmucinous appendiceal adenocarcinomas: role of systemic chemotherapy and cytoreductive surgery

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Marc Uemura, Wei Qiao, Keith Fournier, Jeffrey Morris, Paul Mansfield, Cathy Eng, Richard E Royal, Robert A Wolff, Kanwal Raghav, Gary N Mann, Michael J Overman

Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: final update of the pivotal ERIVANCE BCC study

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Aleksandar Sekulic, Michael R. Migden, Nicole Basset-Seguin, Claus Garbe, Anja Gesierich, Christopher D. Lao, Chris Miller, Laurent Mortier, Dedee F. Murrell, Omid Hamid, Jorge F. Quevedo, Jeannie Hou, Edward McKenna, Natalie Dimier, Sarah Williams, Dirk Schadendorf, Axel Hauschild

PD-L1 expressing circulating tumour cells in head and neck cancers

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• Case report

Arutha Kulasinghe, Chris Perry, Liz Kenny, Majid E. Warkiani, Colleen Nelson, Chamindie Punyadeera

Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma

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Shutaro Yamada, Yoshinori Imura, Takaaki Nakai, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui, Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka

High lymphatic vessel density and presence of lymphovascular invasion both predict poor prognosis in breast cancer

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Song Zhang, Dong Zhang, Mingfu Gong, Li Wen, Cuiwei Liao, Liguang Zou

TUmor-volume to breast-volume RAtio for improving COSmetic results in breast cancer patients (TURACOS); a randomized controlled trial

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M. Lagendijk, E. L. Vos, A. H. J. Koning, M. G. M. Hunink, J. P. Pignol, E. M. L. Corten, C. de Monye, C. H. M. van Deurzen, J. H. van Dam, W. W. Vrijland, C. M. E. Contant, C. Verhoef, W. van Lankeren, L. B. Koppert

Proportion of cancer in a Middle eastern country attributable to established risk factors

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Maya A. Charafeddine, Sara H. Olson, Deborah Mukherji, Sally N. Temraz, Ghassan K. Abou-Alfa, Ali I. Shamseddine

Linking hypoxia, DNA damage and proliferation in multicellular tumor spheroids

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Stephen Riffle, Ram Naresh Pandey, Morgan Albert, Rashmi S. Hegde

Survival rates and predictors of survival among colorectal cancer patients in a Malaysian tertiary hospital

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Bello Arkilla Magaji, Foong Ming Moy, April Camilla Roslani, Chee Wei Law

Cancer incidence among Finnish male cobalt production workers in 1969–2013: a cohort study

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Riitta Sauni, Panu Oksa, Jukka Uitti, Asko Linna, Raimo Kerttula, Eero Pukkala

Validation of the German version of the Mediterranean Diet Adherence Screener (MEDAS) questionnaire

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Katrin Hebestreit, Maryam Yahiaoui-Doktor, Christoph Engel, Walter Vetter, Michael Siniatchkin, Nicole Erickson, Martin Halle, Marion Kiechle, Stephan C. Bischoff

The adaptation of colorectal cancer cells when forming metastases in the liver: expression of associated genes and pathways in a mouse model

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Derya Bocuk, Alexander Wolff, Petra Krause, Gabriela Salinas, Annalen Bleckmann, Christina Hackl, Tim Beissbarth, Sarah Koenig

Cancer risks in a population-based study of 70,570 agricultural workers: results from the Canadian census health and Environment cohort (CanCHEC)

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Linda Kachuri, M. Anne Harris, Jill S. MacLeod, Michael Tjepkema, Paul A. Peters, Paul A. Demers

XLF-mediated NHEJ activity in hepatocellular carcinoma therapy resistance

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Sitian Yang, Xiao Qi Wang

The optimal extent of gastrectomy for middle-third gastric cancer: distal subtotal gastrectomy is superior to total gastrectomy in short-term effect without sacrificing long-term survival

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Xin Ji, Yan Yan, Zhao-De Bu, Zi-Yu Li, Ai-Wen Wu, Lian-Hai Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Shuang-Xi Li, Fei Shan, Zi-Yu Jia, Jia-Fu Ji

The PREgnancy and FERtility (PREFER) study: an Italian multicenter prospective cohort study on fertility preservation and pregnancy issues in young breast cancer patients

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Matteo Lambertini, Paola Anserini, Valeria Fontana, Francesca Poggio, Giuseppina Iacono, Annalisa Abate, Alessia Levaggi, Loredana Miglietta, Claudia Bighin, Sara Giraudi, Alessia D’Alonzo, Eva Blondeaux, Davide Buffi, Francesco Campone, Domenico F. Merlo, Lucia Del Mastro

Anxiety and depression in working-age cancer survivors: a register-based study

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Laura Inhestern, Volker Beierlein, Johanna Christine Bultmann, Birgit Möller, Georg Romer, Uwe Koch, Corinna Bergelt

Barriers and facilitators to smoking cessation in a cancer context: A qualitative study of patient, family and professional views

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Mary Wells, Patricia Aitchison, Fiona Harris, Gozde Ozakinci, Andrew Radley, Linda Bauld, Vikki Entwistle, Alastair Munro, Sally Haw, Bill Culbard, Brian Williams

Hybrid peripheral nerve sheath tumors: report of five cases and detailed review of literature

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• Case report

Nasir Ud Din, Zubair Ahmad, Jamshid Abdul-Ghafar, Rashida Ahmed

Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor – β1 (TGF-β1) and potential effects on migration and invasion

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Synnove Norvoll Magnussen, Elin Hadler-Olsen, Daniela Elena Costea, Eli Berg, Cristiane Cavalcanti Jacobsen, Bente Mortensen, Tuula Salo, Inigo Martinez-Zubiaurre, Jan-Olof Winberg, Lars Uhlin-Hansen, Gunbjorg Svineng

Venous thromboembolism in hospitalized patients receiving chemotherapy for malignancies at Japanese community hospital: prospective observational study

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Hiromitsu Kitayama, Tomohiro Kondo, Junko Sugiyama, Kazutomo Kurimoto, Yasuhiro Nishino, Michiaki Hirayama, Yasushi Tsuji

Notch ligand Delta-like 1 as a novel molecular target in childhood neuroblastoma

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P. Bettinsoli, G. Ferrari-Toninelli, S. A. Bonini, C. Prandelli, M. Memo

Erratum to: Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder

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• Erratum

Makito Miyake, Yosuke Morizawa, Shunta Hori, Nagaaki Marugami, Keiji Shimada, Daisuke Gotoh, Yoshihiro Tatsumi, Yasushi Nakai, Takeshi Inoue, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Nobumichi Tanaka, Kiyohide Fujimoto

Power of PgR expression as a prognostic factor for ER-positive/HER2-negative breast cancer patients at intermediate risk classified by the Ki67 labeling index

• Open Access
• Research article

Sasagu Kurozumi, Hiroshi Matsumoto, Yuji Hayashi, Katsunori Tozuka, Kenichi Inoue, Jun Horiguchi, Izumi Takeyoshi, Tetsunari Oyama, Masafumi Kurosumi

Haemoglobin level increase as an efficacy biomarker during axitinib treatment for metastatic renal cell carcinoma: a retrospective study

• Open Access
• Research article

Alison C. Johnson, Margarida Matias, Helen Boyle, Bernard Escudier, Alicia Molinier, Brigitte Laguerre, Carole Helissey, Pierre-Emmanuel Brachet, Audrey Emmanuelle Dugué, Loic Mourey, Elodie Coquan, Florence Joly

Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis

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• Research article

Virginie Williams, Andrée-Anne Grosset, Natalia Zamorano Cuervo, Yves St-Pierre, Marie-Pierre Sylvestre, Louis Gaboury, Nathalie Grandvaux

Mechanisms of Tanshinone II a inhibits malignant melanoma development through blocking autophagy signal transduction in A375 cell

• Open Access
• Research article

Xiaojing Li, Zhifeng Li, Xianping Li, Baoguo Liu, Zhijun Liu

Use of the QIAGEN GeneReader NGS system for detection of KRAS mutations, validated by the QIAGEN Therascreen PCR kit and alternative NGS platform

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• Research article

Agus Darwanto, Anne-Mette Hein, Sascha Strauss, Yi Kong, Andrew Sheridan, Dan Richards, Eric Lader, Monika Ngowe, Timothy Pelletier, Danielle Adams, Austin Ricker, Nishit Patel, Andreas Kühne, Simon Hughes, Dan Shiffman, Dirk Zimmermann, Kai te Kaat, Thomas Rothmann

Addition of rituximab to CHOP-like chemotherapy in first line treatment of primary mediastinal B-cell lymphoma

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• Research article

K. Lisenko, G. Dingeldein, M. Cremer, M. Kriegsmann, A. D. Ho, M. Rieger, M. Witzens-Harig

Identification of endonuclease domain-containing 1 as a novel tumor suppressor in prostate cancer

• Open Access
• Research article

Jianguang Qiu, Shubin Peng, Jie Si-Tu, Cheng Hu, Wentao Huang, Yunhua Mao, Wenhan Qiu, Ke Li, Dejuan Wang

Oligometastases from prostate cancer: local treatment with stereotactic body radiotherapy (SBRT)

• Open Access
• Research article

Gregor Habl, Christoph Straube, Kilian Schiller, Marciana Nona Duma, Markus Oechsner, Kerstin A. Kessel, Matthias Eiber, Markus Schwaiger, Hubert Kübler, Jürgen E. Gschwend, Stephanie E. Combs

Disparities of time trends and birth cohort effects on invasive breast cancer incidence in Shanghai and Hong Kong pre- and post-menopausal women

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• Research article

Feng Wang, Lap Ah Tse, Wing-cheong Chan, Carol Chi-hei Kwok, Siu-lan Leung, Cherry Wu, Oscar Wai-kong Mang, Roger Kai-cheong Ngan, Mengjie Li, Wai-cho Yu, Koon-ho Tsang, Sze-hong Law, Xiaoping Miao, Chunxiao Wu, Ying Zheng, Fan Wu, Xiaohong R. Yang, Ignatius Tak-sun Yu

First case of B ALL with KMT2A-MAML2 rearrangement: a case report

• Open Access
• Case report

Estelle Menu, Nathalie Beaufils, Fabrice Usseglio, Estelle Balducci, Marina Lafage Pochitaloff, Regis Costello, Jean Gabert

Preoperative cholesterol level as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with cyto-reductive nephrectomy

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Hakmin Lee, Yong June Kim, Eu Chang Hwang, Seok Ho Kang, Sung-Hoo Hong, Jinsoo Chung, Tae Gyun Kwon, Cheol Kwak, Hyeon Hoe Kim, Jong Jin Oh, Sang Chul Lee, Sung Kyu Hong, Sang Eun Lee, Seok-Soo Byun

Time to endoscopic intervention in patients with upper gastrointestinal patients can be improved with pathway provision

• Open Access
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R Singer, P Campbell, C Fernandes, P Statham, D Hochhauser, J Bridgewater

MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis

• Open Access
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Laura Zanotti, Chiara Romani, Laura Tassone, Paola Todeschini, Renata Alessandra Tassi, Elisabetta Bandiera, Giovanna Damia, Francesca Ricci, Laura Ardighieri, Stefano Calza, Sergio Marchini, Luca Beltrame, Germana Tognon, Maurizio D’Incalci, Sergio Pecorelli, Enrico Sartori, Franco Odicino, Antonella Ravaggi, Eliana Bignotti

Insulin-like growth factor 1 receptor affects the survival of primary prostate cancer patients depending on TMPRSS2-ERG status

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Caterina Mancarella, Irene Casanova-Salas, Ana Calatrava, Maria García-Flores, Cecilia Garofalo, Andrea Grilli, José Rubio-Briones, Katia Scotlandi, José Antonio López-Guerrero

Gastric hepatoid adenocarcinoma resulting in a spontaneous gastric perforation: a case report and review of the literature

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• Case report

Junichi Yoshizawa, Satoshi Ishizone, Meguru Ikeyama, Jun Nakayama

The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells

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Brent Voels, Liping Wang, Donald A. Sens, Scott H. Garrett, Ke Zhang, Seema Somji

The role of nature in cancer patients' lives: a systematic review and qualitative meta-synthesis

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Sarah Blaschke

Survival and prognostic factors for survival, cancer specific survival and disease free interval in 239 patients with Hurthle cell carcinoma: a single center experience

• Open Access
• Research article

Branisav Oluic, Ivan Paunovic, Zlatibor Loncar, Vladimir Djukic, Aleksandar Diklic, Milan Jovanovic, Zeljko Garabinovic, Nikola Slijepcevic, Branislav Rovcanin, Dusan Micic, Aleksandar Filipovic, Vladan Zivaljevic

Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy

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• Research article

Akinori Nukui, Akinori Masuda, Hideyuki Abe, Kyoko Arai, Ken-Ichiro Yoshida, Takao Kamai

An increase in long non-coding RNA PANDAR is associated with poor prognosis in clear cell renal cell carcinoma

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• Research article

Yi Xu, Yanyue Tong, Jianyong Zhu, Zhangming Lei, Lijun Wan, Xiuwen Zhu, Feng Ye, Liping Xie

Switch in KRAS mutational status during an unusual course of disease in a patient with advanced pancreatic adenocarcinoma: implications for translational research

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• Case report

Sibylle Baechmann, Steffen Ormanns, Michael Haas, Stephan Kruger, Anna Remold, Dominik Paul Modest, Thomas Kirchner, Andreas Jung, Jens Werner, Volker Heinemann, Stefan Boeck

Prognostic significance of tumor infiltrating immune cells in oral squamous cell carcinoma

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• Research article

Juan Fang, Xiaoxu Li, Da Ma, Xiangqi Liu, Yichen Chen, Yun Wang, Vivian Wai Yan Lui, Juan Xia, Bin Cheng, Zhi Wang

JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells

• Open Access
• Research article

Guobin Tan, Mingning Qiu, Lieqian Chen, Sai Zhang, Longzhi Ke, Jianjun Liu

Phase I/II study of induction chemotherapy using carboplatin plus irinotecan and sequential thoracic radiotherapy (TRT) for elderly patients with limited-disease small-cell lung cancer (LD-SCLC): TORG 0604

• Open Access
• Research article

Yuki Misumi, Hiroaki Okamoto, Jiichiro Sasaki, Noriyuki Masuda, Mari Ishii, Tsuneo Shimokawa, Yukio Hosomi, Yusuke Okuma, Makoto Nagamata, Takashi Ogura, Terufumi Kato, Masafumi Sata, Sakiko Otani, Akira Takakura, Koichi Minato, Yosuke Miura, Takuma Yokoyama, Saori Takata, Katsuhiko Naoki, Koshiro Watanabe

Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration

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Sachi Horibata, Katherine E. Rogers, David Sadegh, Lynne J. Anguish, John L. McElwee, Pragya Shah, Paul R. Thompson, Scott A. Coonrod

Survival and axillary recurrence following sentinel node-positive breast cancer without completion axillary lymph node dissection: the randomized controlled SENOMAC trial

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• Study protocol

Jana de Boniface, Jan Frisell, Yvette Andersson, Leif Bergkvist, Johan Ahlgren, Lisa Rydén, Roger Olofsson Bagge, Malin Sund, Hemming Johansson, Dan Lundstedt, Peer Christiansen, Tove Filtenborg Tvedskov, Birgitte Offersen, Toralf Reimer, Thorsten Kühn, Michalis Kontos, Oreste Gentilini

GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma

• Open Access
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Sheng Zhang, Kang Zhang, Piyou Ji, Xuqing Zheng, Jianbin Jin, Min Feng, Pingguo Liu

Expression of von Hippel–Lindau tumor suppressor protein (pVHL) characteristic of tongue cancer and proliferative lesions in tongue epithelium

• Open Access
• Technical advance

Hisashi Hasegawa, Yoshiaki Kusumi, Takeshi Asakawa, Miyoko Maeda, Toshinori Oinuma, Tohru Furusaka, Takeshi Oshima, Mariko Esumi

Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma

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Nele Kreycy, Christiane Gotzian, Thomas Fleming, Christa Flechtenmacher, Niels Grabe, Peter Plinkert, Jochen Hess, Karim Zaoui

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

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Laurens G. L. Sand, Tessa Buckle, Fijs W. B. van Leeuwen, Willem E. Corver, Alwine B. Kruisselbrink, Aart G. Jochemsen, Pancras C. W. Hogendoorn, Károly Szuhai

Circulating blood levels of IL-6, IFN-γ, and IL-10 as potential diagnostic biomarkers in gastric cancer: a controlled study

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Norma Sánchez-Zauco, Javier Torres, Alejandro Gómez, Margarita Camorlinga-Ponce, Leopoldo Muñoz-Pérez, Roberto Herrera-Goepfert, Rafael Medrano-Guzmán, Silvia Giono-Cerezo, Carmen Maldonado-Bernal

Understanding why cancer patients accept or turn down psycho-oncological support: a prospective observational study including patients’ and clinicians’ perspectives on communication about distress

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Diana Zwahlen, Theresa Tondorf, Sacha Rothschild, Michael T. Koller, Christoph Rochlitz, Alexander Kiss

Calretinin as a blood-based biomarker for mesothelioma

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Georg Johnen, Katarzyna Gawrych, Irina Raiko, Swaantje Casjens, Beate Pesch, Daniel G. Weber, Dirk Taeger, Martin Lehnert, Jens Kollmeier, Torsten Bauer, Arthur W. Musk, Bruce W. S. Robinson, Thomas Brüning, Jenette Creaney

Erratum to: gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol

• Open Access
• Erratum

Charlotte M.C. Oude Ophuis, Lisa B. Koppert, Cécile de Monyé, Carolien H.M. van Deurzen, Senada Koljenović, Alexander C.J. van Akkooi, Cornelis Verhoef, Dirk J. Grünhagen

Combination of Helicobacter pylori infection and the interleukin 8 –251 T > A polymorphism, but not the mannose-binding lectin 2 codon 54 G > A polymorphism, might be a risk factor of gastric cancer

• Open Access
• Research article

Young Woon Chang, Chi Hyuk Oh, Jung-Wook Kim, Jae Won Lee, Mi Ju Park, Jae-Jun Shim, Chang Kyun Lee, Jae-Young Jang, Seok Ho Dong, Hyo Jong Kim, Sung Soo Kim, Byung-Ho Kim

An objective nodal staging system for breast cancer patients undergoing neoadjuvant systemic treatment

• Open Access
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Tae-Kyung Yoo, Jung Min Chang, Hee-Chul Shin, Wonshik Han, Dong-Young Noh, Hyeong-Gon Moon

Single-cell mRNA profiling reveals transcriptional heterogeneity among pancreatic circulating tumour cells

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Morten Lapin, Kjersti Tjensvoll, Satu Oltedal, Milind Javle, Rune Smaaland, Bjørnar Gilje, Oddmund Nordgård

Preoperative Prognostic Nutritional Index is a Significant Predictor of Survival with Bladder Cancer after Radical Cystectomy: a retrospective study

• Open Access
• Research article

Ding Peng, Yan-qing Gong, Han Hao, Zhi-song He, Xue-song Li, Cui-jian Zhang, Li-qun Zhou

Evaluation of treatment response and resistance in metastatic renal cell cancer (mRCC) using integrated 18F–Fluorodeoxyglucose (18F–FDG) positron emission tomography/magnetic resonance imaging (PET/MRI); The REMAP study

• Open Access
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Christian Kelly-Morland, Sarah Rudman, Paul Nathan, Susan Mallett, Giovanni Montana, Gary Cook, Vicky Goh

Treatment patterns and real world clinical outcomes in ER+/HER2- post-menopausal metastatic breast cancer patients in the United States

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Giovanni Zanotti, Matthias Hunger, Julia J Perkins, Ruslan Horblyuk, Monique Martin

Chemotherapy-induced Takotsubo cardiomyopathy, a case report and review of the literature

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• Case report

Matteo Coen, Fabio Rigamonti, Arnaud Roth, Thibaud Koessler

CUL4A overexpression as an independent adverse prognosticator in intrahepatic cholangiocarcinoma

• Open Access
• Research article

Gong -Kai Huang, Ting-Ting Liu, Shao-Wen Weng, Huey-Ling You, Yu-Ching Wei, Chang-Han Chen, Hock-Liew Eng, Wan-Ting Huang

Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

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• Research article

Sophie Sneddon, Ann-Marie Patch, Ian M. Dick, Stephen Kazakoff, John V. Pearson, Nicola Waddell, Richard J. N. Allcock, Robert A. Holt, Bruce W. S. Robinson, Jenette Creaney

A nationwide multi-institutional retrospective study to identify prognostic factors and develop a graded prognostic assessment system for patients with brain metastases from uterine corpus and cervical cancer

• Open Access
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Nakamasa Hayashi, Hideaki Takahashi, Yuzo Hasegawa, Fumi Higuchi, Masamichi Takahashi, Keishi Makino, Masatoshi Takagaki, Jiro Akimoto, Takeshi Okuda, Yoshiko Okita, Koichi Mitsuya, Yasuyuki Hirashima, Yoshitaka Narita, Yoko Nakasu

After accounting for competing causes of death and more advanced stage, do Aboriginal and Torres Strait Islander peoples with cancer still have worse survival? A population-based cohort study in New South Wales

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Hanna E. Tervonen, Richard Walton, Hui You, Deborah Baker, David Roder, David Currow, Sanchia Aranda

Potential mechanisms of resistance to venetoclax and strategies to circumvent it

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Stephen K. Tahir, Morey L. Smith, Paul Hessler, Lisa Roberts Rapp, Kenneth B. Idler, Chang H. Park, Joel D. Leverson, Lloyd T. Lam

Progressive resistance training in head and neck cancer patients during concomitant chemoradiotherapy -- design of the DAHANCA 31 randomized trial

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• Study protocol

Camilla K. Lonkvist, Simon Lønbro, Anders Vinther, Bo Zerahn, Eva Rosenbom, Hanne Primdahl, Pernille Hojman, Julie Gehl

ICORG 10-14: NEOadjuvant trial in Adenocarcinoma of the oEsophagus and oesophagoGastric junction International Study (Neo-AEGIS)

• Open Access
• Study protocol

JV Reynolds, SR Preston, B O’Neill, L Baeksgaard, SM Griffin, C Mariette, S Cuffe, M Cunningham, T Crosby, I Parker, K Hofland, G Hanna, LB Svendsen, CL Donohoe, C Muldoon, D O’Toole, C Johnson, N Ravi, G Jones, AK Corkhill, M Illsley, J Mellor, K Lee, M Dib, V Marchesin, M Cunnane, K Scott, P Lawner, S Warren, S O’Reilly, G O’Dowd, G Leonard, B Hennessy, R Mc Dermott

Most children with cancer are not enrolled on a clinical trial in Canada: a population-based study

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Jason D. Pole, Randy Barber, Rose-Émilie Bergeron, Anne Sophie Carret, David Dix, Ketan Kulkarni, Emilie Martineau, Alicia Randall, David Stammers, Caron Strahlendorf, Douglas R. Strother, Tony H. Truong, Lillian Sung

The prognostic significance of KRAS and BRAF mutation status in Korean colorectal cancer patients

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Daeyoun David Won, Jae Im Lee, In Kyu Lee, Seong-Taek Oh, Eun Sun Jung, Sung Hak Lee

The peripheral monocyte count is associated with the density of tumor-associated macrophages in the tumor microenvironment of colorectal cancer: a retrospective study

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Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Tatsunari Fukuoka, Shigetomi Nakao, Shinji Matsutani, Kosei Hirakawa, Masaichi Ohira

Lipodox® (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx® (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models

• Open Access
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Vinod Burade, Subhas Bhowmick, Kuntal Maiti, Rishit Zalawadia, Harry Ruan, Rajamannar Thennati

Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?

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Christian Arstad, Paulo Refinetti, Annette Torgunrud Kristensen, Karl-Erik Giercksky, Per Olaf Ekstrøm

Phase I study of oral ridaforolimus in combination with paclitaxel and carboplatin in patients with solid tumor cancers

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• Research article

Hye Sook Chon, Sokbom Kang, Jae K. Lee, Sachin M. Apte, Mian M. Shahzad, Irene Williams-Elson, Robert M. Wenham

TRIBE-2: a phase III, randomized, open-label, strategy trial in unresectable metastatic colorectal cancer patients by the GONO group

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• Study protocol

Chiara Cremolini, Federica Marmorino, Fotios Loupakis, Gianluca Masi, Carlotta Antoniotti, Lisa Salvatore, Marta Schirripa, Luca Boni, Vittorina Zagonel, Sara Lonardi, Giuseppe Aprile, Emiliano Tamburini, Vincenzo Ricci, Monica Ronzoni, Filippo Pietrantonio, Chiara Valsuani, Gianluca Tomasello, Alessandro Passardi, Giacomo Allegrini, Samantha Di Donato, Daniele Santini, Alfredo Falcone

Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma

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Chi Wai Yip, Ching Yan Lam, Terence C. W. Poon, Tan To Cheung, Phyllis F. Y. Cheung, Sze Wai Fung, Xiao Qi Wang, Idy C.Y. Leung, Linda W. C. Ng, Chung Mau Lo, George S. W. Tsao, Siu Tim Cheung

Prognostic factors and outcome of Liposarcoma patients: a retrospective evaluation over 15 years

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Carolin Knebel, Ulrich Lenze, Florian Pohlig, Florian Lenze, Norbert Harrasser, Christian Suren, Jonathan Breitenbach, Hans Rechl, Rüdiger von Eisenhart-Rothe, Heinrich M. L. Mühlhofer

Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts

• Open Access
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Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen, Einar K. Rofstad

Pooled safety analyses of ALK-TKI inhibitor in ALK-positive NSCLC

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• Research article

Qian Zhu, Hao Hu, De-Sheng Weng, Xiao-Fei Zhang, Chang-Long Chen, Zi-Qi Zhou, Yan Tang, Jian-Chuan Xia

Internet-based perioperative exercise program in patients with Barrett’s carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial

• Open Access
• Study protocol

Daniel Pfirrmann, Suzan Tug, Oana Brosteanu, Matthias Mehdorn, Martin Busse, Peter P. Grimminger, Florian Lordick, Torben Glatz, Jens Hoeppner, Hauke Lang, Perikles Simon, Ines Gockel

Reduced RCE1 expression predicts poor prognosis of colorectal carcinoma

• Open Access
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Boyun Shi, Xinke Zhou, Lu He, Min Liang, Yuanwei Luo, Peng Jiang

Patterns of venous thromboembolism risk in patients with localized colorectal cancer undergoing adjuvant chemotherapy or active surveillance: an observational cohort study

• Open Access
• Research article

Jakob Michael Riedl, Florian Posch, Angelika Bezan, Joanna Szkandera, Maria Anna Smolle, Thomas Winder, Christopher H. Rossmann, Renate Schaberl-Moser, Martin Pichler, Michael Stotz, Herbert Stöger, Armin Gerger

Effect of transcutaneous electrical stimulation treatment on lower urinary tract symptoms after class III radical hysterectomy in cervical cancer patients: study protocol for a multicentre, randomized controlled trial

• Open Access
• Study protocol

Xiu-Li Sun, Hai-Bo Wang, Zhi-Qi Wang, Ting-ting Cao, Xin Yang, Jing-Song Han, Yang-feng Wu, Kathleen H. Reilly, Jian-Liu Wang

Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters

• Open Access
• Research article

Alison M. McDonnell, Alistair Cook, Bruce W. S. Robinson, Richard A. Lake, Anna K. Nowak

Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors

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Eric Leung, Rob A. Cairns, Naz Chaudary, Ravi N. Vellanki, Tuula Kalliomaki, Eduardo H. Moriyama, Hilda Mujcic, Brian C. Wilson, Bradly G. Wouters, Richard Hill, Michael Milosevic

Prognostic impact of blood and urinary angiogenic factor levels at diagnosis and during treatment in patients with osteosarcoma: a prospective study

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Marie-Dominique Tabone, Laurence Brugières, Sophie Piperno-Neumann, Marie-Ange Selva, Perrine Marec-Bérard, Hélène Pacquement, Cyril Lervat, Nadège Corradini, Jean-Claude Gentet, Rémy Couderc, Aurélie Chevance, Céline Mahier-Ait Oukhatar, Natacha Entz-Werle, Jean-Yves Blay, Marie-Cecile Le Deley

What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group – EWING1

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Ricardo G. Becker, Lauro J. Gregianin, Carlos R. Galia, Reynaldo Jesus-Garcia Filho, Eduardo A. Toller, Gerardo Badell, Suely A. Nakagawa, Alexandre David, André M. Baptista, Eduardo S. Yonamime, Osvaldo A. Serafini, Valter Penna, Julie Francine C. Santos, Algemir L. Brunetto

The dose-response relationship between tobacco smoking and the risk of lymphomas: a case-control study

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Martina Taborelli, Maurizio Montella, Massimo Libra, Rosamaria Tedeschi, Anna Crispo, Maria Grimaldi, Luigino Dal Maso, Diego Serraino, Jerry Polesel

Characterization of MicroRNA-200 pathway in ovarian cancer and serous intraepithelial carcinoma of fallopian tube

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Junzheng Yang, Yilan Zhou, Shu-Kay Ng, Kuan-Chun Huang, Xiaoyan Ni, Pui-Wah Choi, Kathleen Hasselblatt, Michael G. Muto, William R. Welch, Ross S. Berkowitz, Shu-Wing Ng

Breast cancer patient delay in Fukushima, Japan following the 2011 triple disaster: a long-term retrospective study

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Akihiko Ozaki, Shuhei Nomura, Claire Leppold, Masaharu Tsubokura, Tetsuya Tanimoto, Takeru Yokota, Shigehira Saji, Toyoaki Sawano, Manabu Tsukada, Tomohiro Morita, Sae Ochi, Shigeaki Kato, Masahiro Kami, Tsuyoshi Nemoto, Yukio Kanazawa, Hiromichi Ohira

Anaplastic astrocytoma mimicking progressive multifocal leucoencephalopathy: a case report and review of the overlapping syndromes

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• Case report

Ema Kantorová, Michal Bittšanský, Štefan Sivák, Eva Baranovičová, Petra Hnilicová, Vladimír Nosáľ, Daniel Čierny, Kamil Zeleňák, Wolfgang Brück, Egon Kurča

A phase 2 randomized trial to evaluate the impact of a supervised exercise program on cardiotoxicity at 3 months in patients with HER2 overexpressing breast cancer undergoing adjuvant treatment by trastuzumab: design of the CARDAPAC study

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• Study protocol

Quentin Jacquinot, Nathalie Meneveau, Marion Chatot, Franck Bonnetain, Bruno Degano, Malika Bouhaddi, Gilles Dumoulin, Dewi Vernerey, Xavier Pivot, Fabienne Mougin

African-American esophageal squamous cell carcinoma expression profile reveals dysregulation of stress response and detox networks

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• Research article

Hayriye Verda Erkizan, Kory Johnson, Svetlana Ghimbovschi, Deepa Karkera, Gregory Trachiotis, Houtan Adib, Eric P. Hoffman, Robert G. Wadleigh

Strain elastography imaging for early detection and prediction of tumor response to concurrent chemo-radiotherapy in locally advanced cervical cancer: feasibility study

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• Research article

Yan Xu, Lijing Zhu, Baorui Liu, Tong Ru, Huanhuan Wang, Jian He, Song Liu, Xiaofeng Yang, Zhengyang Zhou, Tian Liu

Droplet digital PCR for detection and quantification of circulating tumor DNA in plasma of head and neck cancer patients

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• Research article

Joost H. van Ginkel, Manon M. H. Huibers, Robert J. J. van Es, Remco de Bree, Stefan M. Willems

Personalised informed choice on evidence and controversy on mammography screening: study protocol for a randomized controlled trial

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• Study protocol

Anna Roberto, Cinzia Colombo, Giulia Candiani, Livia Giordano, Paola Mantellini, Eugenio Paci, Roberto Satolli, Mario Valenza, Paola Mosconi

Retinal and vitreous metastases from hepatocholangiocarcinoma

• Open Access
• Case report

Anna Praidou, Sarita Jacob, Luciane Irion, Ramesh Sivaraj, Carl Groenewald, Sarah E. Coupland, Heinrich Heimann

Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis

• Open Access
• Research article

Nhi Huynh, Kai Wang, Mildred Yim, Chelsea J. Dumesny, Mauro S. Sandrin, Graham S. Baldwin, Mehrdad Nikfarjam, Hong He

Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

• Open Access
• Research article

Jin Zheng, Chuize Kong, Xiaoxi Yang, Xiaolu Cui, Xuyong Lin, Zhe Zhang

Utility of the sentinel node concept for detection of lateral pelvic lymph node metastasis in lower rectal cancer

• Open Access
• Research article

Shigehiro Yanagita, Yoshikazu Uenosono, Takaaki Arigami, Yoshiaki Kita, Shinichiro Mori, Shoji Natsugoe

Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma

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• Research article

Anderson H. Webb, Bradley T. Gao, Zachary K. Goldsmith, Andrew S. Irvine, Nabil Saleh, Ryan P. Lee, Justin B. Lendermon, Rajini Bheemreddy, Qiuhua Zhang, Rachel C. Brennan, Dianna Johnson, Jena J. Steinle, Matthew W. Wilson, Vanessa M. Morales-Tirado

HPV and cofactors for invasive cervical cancer in Morocco: a multicentre case-control study

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Mohamed Berraho, Afaf Amarti-Riffi, Mohammed El-Mzibri, Rachid Bezad, Noureddine Benjaafar, Abdelatif Benideer, Noureddine Matar, Zinab Qmichou, Naima Abda, Mohammed Attaleb, Kaoutar Znati, Hind El Fatemi, Karima Bendahhou, Majdouline Obtel, Abdelhai Filali Adib, Simone Mathoulin-Pelissier, Chakib Nejjari

Curative resection by splenectomy for solitary splenic metastasis from early gastric cancer: a case report and literature review

• Open Access
• Case report

Junichi Yoshizawa, Naoki Kubo, Satoshi Ishizone, Fumitoshi Karasawa, Ataru Nakayama

Examination of multiple UGT1A and DPYD polymorphisms has limited ability to predict the toxicity and efficacy of metastatic colorectal cancer treated with irinotecan-based chemotherapy: a retrospective analysis

• Open Access
• Research article

Dan Liu, Jian Li, Jing Gao, Yanyan Li, Rui Yang, Lin Shen

Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers

• Open Access
• Research article

Eli Marie Grindedal, Cecilie Heramb, Inga Karsrud, Sarah Louise Ariansen, Lovise Mæhle, Dag Erik Undlien, Jan Norum, Ellen Schlichting

Cerebellar mutism syndrome in children with brain tumours of the posterior fossa

• Open Access
• Study protocol

Morten Wibroe, Johan Cappelen, Charlotte Castor, Niels Clausen, Pernilla Grillner, Thora Gudrunardottir, Ramneek Gupta, Bengt Gustavsson, Mats Heyman, Stefan Holm, Atte Karppinen, Camilla Klausen, Tuula Lönnqvist, René Mathiasen, Pelle Nilsson, Karsten Nysom, Karin Persson, Olof Rask, Kjeld Schmiegelow, Astrid Sehested, Harald Thomassen, Ingrid Tonning-Olsson, Barbara Zetterqvist, Marianne Juhler

A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model

• Open Access
• Research article

Shih-Hsin Tu, Yi-Chen Hsieh, Li-Chi Huang, Chun-Yu Lin, Kai-Wen Hsu, Wen-Shyang Hsieh, Wei-Ming Chi, Chia-Hwa Lee

The correlation between poor prognosis and increased yes-associated protein 1 expression in keratin 19 expressing hepatocellular carcinomas and cholangiocarcinomas

• Open Access
• Research article

KyuHo Lee, Kyoung-Bun Lee, Hae Yoen Jung, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Ja-June Jang

Acute myeloid leukemia and pregnancy: clinical experience from a single center and a review of the literature

• Open Access
• Research article

Nicola Stefano Fracchiolla, Mariarita Sciumè, Francesco Dambrosi, Francesca Guidotti, Manuela Wally Ossola, Giovanna Chidini, Umberto Gianelli, Daniela Merlo, Agostino Cortelezzi

Erratum to: Solitary plasmacytoma: population-based analysis of survival trends and effect of various treatment modalities in the USA

• Open Access
• Erratum

Nishitha Thumallapally, Ahmed Meshref, Mohammed Mousa, Terenig Terjanian

Within-class differences in cancer risk for sulfonylurea treatments in patients with type 2 diabetes (ZODIAC-55) – a study protocol

• Open Access
• Study protocol

Dennis Schrijnders, Geertruida H. de Bock, Sebastiaan T. Houweling, Kornelis J. J. van Hateren, Klaas H. Groenier, Jeffrey A. Johnson, Henk J. G. Bilo, Nanne Kleefstra, Gijs W. D. Landman

Clinical outcomes of transoral videolaryngoscopic surgery for hypopharyngeal and supraglottic cancer

• Open Access
• Research article

Yorihisa Imanishi, Hiroyuki Ozawa, Koji Sakamoto, Ryoichi Fujii, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Mariko Sekimizu, Fumihiro Ito, Toshiki Tomita, Kaoru Ogawa

Development of a computer-tailored physical activity intervention for prostate and colorectal cancer patients and survivors: OncoActive

• Open Access
• Study protocol

R. H. J. Golsteijn, C. Bolman, E. Volders, D. A. Peels, H. de Vries, L. Lechner

Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration

• Open Access
• Research article

Princy Parsana, Sarah R. Amend, James Hernandez, Kenneth J. Pienta, Alexis Battle

The effect of geriatric intervention in frail elderly patients receiving chemotherapy for colorectal cancer: a randomized trial (GERICO)

• Open Access
• Study protocol

C. M. Lund, K. K. Vistisen, C. Dehlendorff, F. Rønholt, J. S. Johansen, D. L. Nielsen

Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis

• Open Access
• Research article

Xinfang Yu, Wei Li, Zhenkun Xia, Li Xie, Xiaolong Ma, Qi Liang, Lijun Liu, Jian Wang, Xinmin Zhou, Yifeng Yang, Haidan Liu

CMISG1701: a multicenter prospective randomized phase III clinical trial comparing neoadjuvant chemoradiotherapy to neoadjuvant chemotherapy followed by minimally invasive esophagectomy in patients with locally advanced resectable esophageal squamous cell carcinoma (cT3-4aN0-1M0) (NCT03001596)

• Open Access
• Study protocol

Han Tang, Lijie Tan, Yaxing Shen, Hao Wang, Miao Lin, Mingxiang Feng, Songtao Xu, Weigang Guo, Cheng Qian, Tianshu Liu, Zhaochong Zeng, Yingyong Hou, Zhentao Yu, Hongjing Jiang, Zhigang Li, Chun Chen, Changhong Lian, Ming Du, Hecheng Li, Deyao Xie, Jun Yin, Naiqing Zhao, Qun Wang

Prognostic and predictive factors in patients with metastatic or recurrent cervical cancer treated with platinum-based chemotherapy.

• Open Access
• Research article

Sofia Karageorgopoulou, Ioannis D. Kostakis, Maria Gazouli, Sonia Markaki, Marios Papadimitriou, Evangelos Bournakis, Meletios-Athanassios Dimopoulos, Christos A Papadimitriou

E3 ubiquitin ligase, RNF139, inhibits the progression of tongue cancer

• Open Access
• Research article

Lina Wang, Wei Yin, Chun Shi

A phase II randomized trial of Observation versus stereotactic ablative RadiatIon for OLigometastatic prostate CancEr (ORIOLE)

• Open Access
• Study protocol

Noura Radwan, Ryan Phillips, Ashley Ross, Steven P. Rowe, Michael A. Gorin, Emmanuel S. Antonarakis, Curtiland Deville, Stephen Greco, Samuel Denmeade, Channing Paller, Daniel Y. Song, Maximilian Diehn, Hao Wang, Michael Carducci, Kenneth J. Pienta, Martin G. Pomper, Theodore L. DeWeese, Adam Dicker, Mario Eisenberger, Phuoc T. Tran

Robot-assisted radical prostatectomy significantly reduced biochemical recurrence compared to retro pubic radical prostatectomy

• Open Access
• Research article

Tetsuya Fujimura, Hiroshi Fukuhara, Satoru Taguchi, Yuta Yamada, Toru Sugihara, Tohru Nakagawa, Aya Niimi, Haruki Kume, Yasuhiko Igawa, Yukio Homma

Dickkopf-4 is frequently overexpressed in epithelial ovarian carcinoma and promotes tumor invasion

• Open Access
• Research article

Shizhuo Wang, Heng Wei, Shulan Zhang

The role of hormonal therapy in patients with relapsed high-grade ovarian carcinoma: a retrospective series of tamoxifen and letrozole

• Open Access
• Research article

Angela George, Jennifer McLachlan, Nina Tunariu, Chiara Della Pepa, Cristina Migali, Martin Gore, Stan Kaye, Susana Banerjee

Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications

• Open Access
• Research article

Shonan Sho, Colin M. Court, Paul Winograd, Sangjun Lee, Shuang Hou, Thomas G. Graeber, Hsian-Rong Tseng, James S. Tomlinson

miRNome landscape analysis reveals a 30 miRNA core in retinoblastoma

• Open Access
• Research article

Blanca Elena Castro-Magdonel, Manuela Orjuela, Javier Camacho, Adda Jeanette García-Chéquer, Lourdes Cabrera-Muñoz, Stanislaw Sadowinski-Pine, Noé Durán-Figueroa, María de Jesús Orozco-Romero, Ana Claudia Velázquez-Wong, Adriana Hernández-Ángeles, Claudia Hernández-Galván, Citlali Lara-Molina, M. Verónica Ponce-Castañeda

Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08)

• Open Access
• Study protocol

L. M. van Roozendaal, M. L. G. Vane, T. van Dalen, J. A. van der Hage, L. J. A. Strobbe, L. J. Boersma, S. C. Linn, M. B. I. Lobbes, P. M. P. Poortmans, V. C. G. Tjan-Heijnen, K. K. B. T. Van de Vijver, J. de Vries, A. H. Westenberg, A. G. H. Kessels, J. H. W. de Wilt, M. L. Smidt

Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex

• Open Access
• Research article

Louisa M. Salemi, Matthew E. R. Maitland, Eyal R. Yefet, Caroline Schild-Poulter

A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

• Open Access
• Study protocol

Mikkel Bandak, Niels Jørgensen, Anders Juul, Jakob Lauritsen, Michael Kreiberg, Peter Sandor Oturai, Jørn Wulff Helge, Gedske Daugaard

A multicenter survey of first-line treatment patterns and gene aberration test status of patients with unresectable Stage IIIB/IV nonsquamous non-small cell lung cancer in China (CTONG 1506)

• Open Access
• Research article

Qing Zhou, Yong Song, Xin Zhang, Gong-Yan Chen, Dian-Sheng Zhong, Zhuang Yu, Ping Yu, Yi-Ping Zhang, Jian-Hua Chen, Yi Hu, Guo-Sheng Feng, Xia Song, Qiang Shi, Lu Lu Yang, Ping Hai Zhang, Yi-Long Wu

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression

• Open Access
• Research article

Delores J. Grant, Zinan Chen, Lauren E. Howard, Emily Wiggins, Amanda De Hoedt, Adriana C. Vidal, Skyla T. Carney, Jill Squires, Clara E. Magyar, Jiaoti Huang, Stephen J. Freedland

Risk stratification system to predict recurrence of intrahepatic cholangiocarcinoma after hepatic resection

• Open Access
• Research article

Seogsong Jeong, Qingbao Cheng, Lifeng Huang, Jian Wang, Meng Sha, Ying Tong, Lei Xia, Longzhi Han, Zhifeng Xi, Jianjun Zhang, Xiaoni Kong, Jinyang Gu, Qiang Xia

Study protocol: multi-parametric magnetic resonance imaging for therapeutic response prediction in rectal cancer

• Open Access
• Study protocol

Trang Thanh Pham, Gary Liney, Karen Wong, Robba Rai, Mark Lee, Daniel Moses, Christopher Henderson, Michael Lin, Joo-Shik Shin, Michael Bernard Barton

Effects of an interactive mHealth innovation for early detection of patient-reported symptom distress with focus on participatory care: protocol for a study based on prospective, randomised, controlled trials in patients with prostate and breast cancer

• Open Access
• Study protocol

Ann Langius-Eklöf, Marie-Therése Crafoord, Mats Christiansen, Maria Fjell, Kay Sundberg

Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer

• Open Access
• Research article

Eun Young Kim, Ji Ye Jung, Arum Kim, Kwangsoo Kim, Yoon Soo Chang

A comprehensive overview on the surgical management of secondary lymphedema of the upper and lower extremities related to prior oncologic therapies

• Open Access
• Review

Ramon Garza III, Roman Skoracki, Karen Hock, Stephen P. Povoski

CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

• Open Access
• Research article

Olafur Andri Stefansson, Stefan Hermanowicz, Jasper van der Horst, Holmfridur Hilmarsdottir, Zuzanna Staszczak, Jon Gunnlaugur Jonasson, Laufey Tryggvadottir, Thorkell Gudjonsson, Stefan Sigurdsson

Evolution of educational inequalities in site-specific cancer mortality among Belgian men between the 1990s and 2000s using a “fundamental cause” perspective

• Open Access
• Research article

Katrien Vanthomme, Hadewijch Vandenheede, Paulien Hagedoorn, Sylvie Gadeyne

ALK-rearranged lung squamous cell carcinoma responding to alectinib: a case report and review of the literature

• Open Access
• Case report

Nobuaki Mamesaya, Kazuhisa Nakashima, Tateaki Naito, Takashi Nakajima, Masahiro Endo, Toshiaki Takahashi

MALDI-TOF-MS analysis in discovery and identification of serum proteomic patterns of ovarian cancer

• Open Access
• Research article

Agata Swiatly, Agnieszka Horala, Joanna Hajduk, Jan Matysiak, Ewa Nowak-Markwitz, Zenon J. Kokot

Regulation of early growth response 2 expression by secreted frizzled related protein 1

• Open Access
• Research article

Kelly J. Gregory, Stephanie M. Morin, Sallie S. Schneider

The effects of the location of cancer stem cell marker CD133 on the prognosis of hepatocellular carcinoma patients

• Open Access
• Research article

Yao-Li Chen, Ping-Yi Lin, Ying-Zi Ming, Wei-Chieh Huang, Rong-Fu Chen, Po-Ming Chen, Pei-Yi Chu

Multiparametric magnetic resonance imaging in mucosal primary head and neck cancer: a prospective imaging biomarker study

• Open Access
• Study protocol

Christopher N Rumley, Mark T Lee, Lois Holloway, Robba Rai, Myo Min, Dion Forstner, Allan Fowler, Gary Liney

Communication about uncertainty and hope: A randomized controlled trial assessing the efficacy of a communication skills training program for physicians caring for cancer patients

• Open Access
• Study protocol

Yves Libert, Livia Peternelj, Isabelle Bragard, Aurore Liénard, Isabelle Merckaert, Christine Reynaert, Darius Razavi

JMJD2A promotes the Warburg effect and nasopharyngeal carcinoma progression by transactivating LDHA expression

• Open Access
• Research article

Yi Su, Qiu-hong Yu, Xiang-yun Wang, Li-ping Yu, Zong-feng Wang, Ying-chun Cao, Jian-dong Li

High cancer mortality for US-born Latinos: evidence from California and Texas

• Open Access
• Research article

Paulo S. Pinheiro, Karen E. Callahan, Scarlett Lin Gomez, Rafael Marcos-Gragera, Taylor R. Cobb, Aina Roca-Barcelo, Amelie G. Ramirez

Joint quantitative measurement of hTERT mRNA in both peripheral blood and circulating tumor cells of patients with nasopharyngeal carcinoma and its clinical significance

• Open Access
• Research article

Xinsa Fu, Congxiang Shen, Huigang Wang, Fang Chen, Guanxue Li, Zhong Wen

Proteomic characterization of paired non-malignant and malignant African-American prostate epithelial cell lines distinguishes them by structural proteins

• Open Access
• Research article

Jennifer S. Myers, Karin A. Vallega, Jason White, Kaixian Yu, Clayton C. Yates, Qing-Xiang Amy Sang

A novel algorithm for the treatment strategy for advanced epithelial ovarian cancer: consecutive imaging, frailty assessment, and diagnostic laparoscopy

• Open Access
• Research article

Kyung Jin Eoh, Jung Won Yoon, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim

Long-term effects and psychological adjustment: study protocol of a large register-based study on quality of life among survivors of hematological malignancies

• Open Access
• Study protocol

Peter Esser, Katharina Kuba, Heide Götze, Anja Mehnert

Chemoradiation in elderly esophageal cancer patients: rationale and design of a phase I/II multicenter study (OSAGE)

• Open Access
• Study protocol

Stéphanie Servagi-Vernat, Gilles Créhange, Franck Bonnetain, Cécile Mertens, Etienne Brain, Jean François Bosset

Elevated serum CEA levels are associated with the explosive progression of lung adenocarcinoma harboring EGFR mutations

• Open Access
• Research article

Yuan Gao, PingPing Song, Hui Li, Hui Jia, BaiJiang Zhang

Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth

• Open Access
• Research article

Clarissa N. Amaya, Dianne C. Mitchell, Brad A. Bryan

Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways

• Open Access
• Research article

Hongyu Guan, Zejun Guo, Weiwei Liang, Hai Li, Guohong Wei, Lijuan Xu, Haipeng Xiao, Yanbing Li

Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition

• Open Access
• Research article

Chatarina Larsson, Muhammad Akhtar Ali, Tatjana Pandzic, Anders M. Lindroth, Liqun He, Tobias Sjöblom

β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells

• Open Access
• Research article

Evelina Miele, Agnese Po, Federica Begalli, Laura Antonucci, Angela Mastronuzzi, Carlo Efisio Marras, Andrea Carai, Danilo Cucchi, Luana Abballe, Zein Mersini Besharat, Giuseppina Catanzaro, Paola Infante, Lucia Di Marcotullio, Gianluca Canettieri, Enrico De Smaele, Isabella Screpanti, Franco Locatelli, Elisabetta Ferretti

Quantitation of DNA methylation in Epstein-Barr virus–associated nasopharyngeal carcinoma by bisulfite amplicon sequencing

• Open Access
• Research article

Weilin Zhao, Yingxi Mo, Shumin Wang, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Guangwu Huang, Zhe Zhang, Mariko Murata, Kazuhiko Takeuchi

Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

• Open Access
• Research article

Eva Lhuissier, Céline Bazille, Juliette Aury-Landas, Nicolas Girard, Julien Pontin, Martine Boittin, Karim Boumediene, Catherine Baugé

Psychosocial and behavioral impact of breast cancer risk assessed by testing for common risk variants: protocol of a prospective study

• Open Access
• Study protocol

Tatiane Yanes, Bettina Meiser, Mary-Anne Young, Rajneesh Kaur, Gillian Mitchell, Kristine Barlow-Stewart, Tony Roscioli, Jane Halliday, Paul James

Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells

• Open Access
• Research article

Qian Wang, Yu Cheng, Yan Wang, Yibo Fan, Ce Li, Ye Zhang, Yiding Wang, Qian Dong, Yanju Ma, Yue-e Teng, Xiujuan Qu, Yunpeng Liu

Real-life clinical practice results with vinflunine in patients with relapsed platinum-treated metastatic urothelial carcinoma: an Italian multicenter study (MOVIE-GOIRC 01–2014)

• Open Access
• Research article

Rodolfo Passalacqua, Silvia Lazzarelli, Maddalena Donini, Rodolfo Montironi, Rosa Tambaro, Ugo De Giorgi, Sandro Pignata, Raffaella Palumbo, Giovanni Luca Ceresoli, Gianluca Del Conte, Giuseppe Tonini, Franco Morelli, Franco Nolè, Stefano Panni, Ermanno Rondini, Annalisa Guida, Paolo Andrea Zucali, Laura Doni, Elisa Iezzi, Caterina Caminiti

Metformin and longevity (METAL): a window of opportunity study investigating the biological effects of metformin in localised prostate cancer

• Open Access
• Study protocol

Danielle Crawley, Ashish Chandra, Massimo Loda, Cheryl Gillett, Paul Cathcart, Ben Challacombe, Gary Cook, Declan Cahill, Aida Santa Olalla, Fidelma Cahill, Gincy George, Sarah Rudman, Mieke Van Hemelrijck

Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

• Open Access
• Research article

Humair S. Quadri, Taylor J. Aiken, Michael Allgaeuer, Radim Moravec, Sean Altekruse, S. Perwez Hussain, Markku M. Miettinen, Stephen M. Hewitt, Udo Rudloff

Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families

• Open Access
• Research article

Kirsi M. Määttä, Riikka Nurminen, Minna Kankuri-Tammilehto, Anne Kallioniemi, Satu-Leena Laasanen, Johanna Schleutker

Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma

• Open Access
• Research article

Trisha Dwight, Un Na, Edward Kim, Ying Zhu, Anne Louise Richardson, Bruce G. Robinson, Katherine M. Tucker, Anthony J. Gill, Diana E. Benn, Roderick J. Clifton-Bligh, Dennis R. Winge

Assessing the adequacy of lymph node yield for different tumor stages of colon cancer by nodal staging scores

• Open Access
• Research article

Zhenyu Wu, Guoyou Qin, Naiqing Zhao, Huixun Jia, Xueying Zheng

A randomized phase II study of paclitaxel alone versus paclitaxel plus sorafenib in second- and third-line treatment of patients with HER2-negative metastatic breast cancer (PASO)

• Open Access
• Research article

Thomas Decker, Friedrich Overkamp, Siegfried Rösel, Arnd Nusch, Thomas Göhler, Martin Indorf, Jörg Sahlmann, Tanja Trarbach

Whole brain radiotherapy versus stereotactic radiosurgery for 4–10 brain metastases: a phase III randomised multicentre trial

• Open Access
• Study protocol

Jaap D. Zindler, Anna M. E. Bruynzeel, Daniëlle B. P. Eekers, Coen W. Hurkmans, Ans Swinnen, Philippe Lambin

Association between the XRCC1 polymorphisms and clinical outcomes of advanced NSCLC treated with platinum-based chemotherapy: a meta-analysis based on the PRISMA statement

• Open Access
• Research article

Dan-Juan Li, Dong Xiao

Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy

• Open Access
• Research article

Vienna Ludovini, Cinzia Antognelli, Antonio Rulli, Jennifer Foglietta, Lorenza Pistola, Rulli Eliana, Irene Floriani, Giuseppe Nocentini, Francesca Romana Tofanetti, Simonetta Piattoni, Elisa Minenza, Vincenzo Nicola Talesa, Angelo Sidoni, Maurizio Tonato, Lucio Crinò, Stefania Gori

Vaginal metastasis as the initial presentation of leiomyosarcoma: a case report

• Open Access
• Case report

Cecilia Villalaín-González, Álvaro Tejerizo-García, Patricia Lopez-Garcia, Gregorio López-González, Ma. Reyes Oliver-Perez, Jesús S. Jiménez-López

Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer

• Open Access
• Research article

Frank Jacobsen, Billurvan Taskin, Nathaniel Melling, Charlotte Sauer, Corinna Wittmer, Claudia Hube-Magg, Martina Kluth, Ronald Simon, Dirk Pehrke, Burkhard Beyer, Thomas Steuber, Imke Thederan, Guido Sauter, Thorsten Schlomm, Waldemar Wilczak, Katharina Möller, Sören A. Weidemann, Susanne Burdak-Rothkamm

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas

• Open Access
• Study protocol

Matthew H. G. Katz, Fang-Shu Ou, Joseph M. Herman, Syed A. Ahmad, Brian Wolpin, Robert Marsh, Spencer Behr, Qian Shi, Michael Chuong, Lawrence H. Schwartz, Wendy Frankel, Eric Collisson, Eugene J. Koay, JoLeen M. Hubbard, James L. Leenstra, Jeffrey Meyerhardt, Eileen O’Reilly

Prognostic value of total tumor volume in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

• Open Access
• Research article

Shao-Bo Liang, Jian-Jian Teng, Xue-Feng Hu, Xing-Li Yang, Min Luo, Xiao-Na Fang, Dong-Sheng Liu, Yong Chen, Li-Wu Fu

Successful treatment with anti-programmed-death-1 antibody in a relapsed natural killer/T-cell lymphoma patient with multi-line resistance: a case report

• Open Access
• Case report

Jianping Lai, Peng Xu, Xiaoliu Jiang, Shan Zhou, Anwen Liu

PUREAIR protocol: randomized controlled trial of intensive pulmonary rehabilitation versus standard care in patients undergoing surgical resection for lung cancer

• Open Access
• Study protocol

Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Besa Kopliku, Cristian Rapicetta, Roberto Piro, Roberta Bardelli, Patricia Filipa Sobral Rebelo, Carla Galeone, Giorgio Sgarbi, Filippo Lococo, Massimiliano Paci, Tommaso Ricchetti, Silvio Cavuto, Domenico Franco Merlo, Sara Tenconi

Randomized controlled trial of S-1 maintenance therapy in metastatic esophagogastric cancer – the multinational MATEO study

• Open Access
• Study protocol

Georg-Martin Haag, Gertraud Stocker, Julia Quidde, Dirk Jaeger, Florian Lordick

Outcome and toxicity of radical radiotherapy or concurrent Chemoradiotherapy for elderly cervical cancer women

• Open Access
• Research article

Weiping Wang, Xiaorong Hou, Junfang Yan, Jie Shen, Xin Lian, Shuai Sun, Zhikai Liu, Qingyu Meng, Dunhuang Wang, Mei Zhao, Jie Qiu, Ke Hu, Fuquan Zhang

Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients

• Open Access
• Research article

Li Wang, Sarrah E. Widatalla, Diva S. Whalen, Josiah Ochieng, Amos M. Sakwe

Succinate dehydrogenase deficiency in a PDGFRA mutated GIST

• Open Access
• Research article

Martin G. Belinsky, Kathy Q. Cai, Yan Zhou, Biao Luo, Jianming Pei, Lori Rink, Margaret von Mehren

Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization

• Open Access
• Research article

Lin Wang, Xiaozhong Li, Louxin Zhang, Qiang Gao

Lymphocyte count or percentage: which can better predict the prognosis of advanced cancer patients following palliative care?

• Open Access
• Research article

Weiwei Zhao, Peng Wang, Huixun Jia, Menglei Chen, Xiaoli Gu, Minghui Liu, Zhe Zhang, Wenwu Cheng, Zhenyu Wu

Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells

• Open Access
• Research article

Daria Gauck, Silvia Keil, Bernd Niggemann, Kurt S. Zänker, Thomas Dittmar

Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses

• Open Access
• Technical advance

Averey D. Strong, Richard L. Daniels

Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease

• Open Access
• Research article

Jing Li, Ni-ya Ning, Qun-xian Rao, Rong Chen, Li-juan Wang, Zhong-qiu Lin

Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile

• Open Access
• Research article

Priscilla Brebi, Carmen Gloria Ili, Alejandra Andana, Doris Menzel, Jaime Lopez, Pablo Guzman, Angelica Melo, Kurt Buchegger, Juan C. Roa

Novel approaches to the prediction, diagnosis and treatment of cardiac late effects in survivors of childhood cancer: a multi-centre observational study

• Open Access
• Study protocol

Amy Skitch, Seema Mital, Luc Mertens, Peter Liu, Paul Kantor, Lars Grosse-Wortmann, Cedric Manlhiot, Mark Greenberg, Paul C Nathan

Complete surgical resection improves outcome in INRG high-risk patients with localized neuroblastoma older than 18 months

• Open Access
• Research article

Janina Fischer, Alexandra Pohl, Ruth Volland, Barbara Hero, Martin Dübbers, Grigore Cernaianu, Frank Berthold, Dietrich von Schweinitz, Thorsten Simon

Clinicopathological features and prognostic validity of WHO grading classification of SI-NENs

• Open Access
• Research article

Luohai Chen, Lin Zhou, Meng Zhang, Liang Shang, Panpan Zhang, Wei Wang, Cheng Fang, Jingnan Li, Tianming Xu, Huangying Tan, Pan Zhang, Meng Qiu, Xianjun Yu, Kaizhou Jin, Ye Chen, Huishan Chen, Rong Lin, Qin Zhang, Lin Shen, Minhu Chen, Jie Li, Leping Li, Jie Chen

Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study

• Open Access
• Research article

Johannes Baur, Tjark-Ole Büntemeyer, Felix Megerle, Timo Deutschbein, Christine Spitzweg, Marcus Quinkler, Peter Nawroth, Matthias Kroiss, Christoph-Thomas Germer, Martin Fassnacht, Ulrich Steger

The clonal evolution of two distinct T315I-positive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: a case report

• Open Access
• Case report

Caterina De Benedittis, Cristina Papayannidis, Claudia Venturi, Maria Chiara Abbenante, Stefania Paolini, Sarah Parisi, Chiara Sartor, Michele Cavo, Giovanni Martinelli, Simona Soverini

Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional study

• Open Access
• Research article

Carolina Guiriguet, Guillem Pera, Antoni Castells, Pere Toran, Jaume Grau, Irene Rivero, Andrea Buron, Francesc Macià, Carmen Vela-Vallespín, Mercedes Vilarrubí-Estrella, Mercedes Marzo-Castillejo

A pilot evaluation of magnetic resonance imaging characteristics seen with solid papillary carcinomas of the breast in 4 patients

• Open Access
• Research article

Lina Zhang, Ling Zhuang, Chang Shi, Yanwei Miao, Weisheng Zhang, Qingwei Song, Jianyun Kang, Zhijin Lang, Xuegang Xin, Ailian Liu, Jiani Hu

Pirfenidone as salvage treatment for refractory bleomycin-induced lung injury: a case report of seminoma

• Open Access
• Case report

Koji Sakamoto, Satoru Ito, Naozumi Hashimoto, Yoshinori Hasegawa

Levels of activated platelet-derived microvesicles in patients with soft tissue sarcoma correlate with an increased risk of venous thromboembolism

• Open Access
• Research article

A. Fricke, P. V. Ullrich, A. F. V. Cimniak, C. Becherer, M. Follo, J. Heinz, J. Scholber, G. W. Herget, O. Hauschild, U. A. Wittel, G. B. Stark, H. Bannasch, D. Braig, S. U. Eisenhardt

Hedgehog inhibitor sonidegib potentiates 177Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude mice

• Open Access
• Research article

Johan Spetz, Britta Langen, Nils Rudqvist, Toshima Z. Parris, Khalil Helou, Ola Nilsson, Eva Forssell-Aronsson

The cost-effectiveness of active surveillance compared to watchful waiting and radical prostatectomy for low risk localised prostate cancer

• Open Access
• Research article

Chunhuan Lao, Richard Edlin, Paul Rouse, Charis Brown, Michael Holmes, Peter Gilling, Ross Lawrenson

Squamous differentiation in patients with superficial bladder urothelial carcinoma is associated with high risk of recurrence and poor survival

• Open Access
• Research article

Gang Li, Jianpeng Yu, Hualin Song, Shimiao Zhu, Libin Sun, Zhiqun Shang, Yuanjie Niu

High prevalence of co-infection between human papillomavirus (HPV) 51 and 52 in Mexican population

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Jazbet Gallegos-Bolaños, Jessica Alejandra Rivera-Domínguez, José Miguel Presno-Bernal, Rodolfo Daniel Cervantes-Villagrana

Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivo

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Maciej Tarnowski, Marta Tkacz, Katarzyna Zgutka, Joanna Bujak, Patrycja Kopytko, Andrzej Pawlik

The effect of Nullomer-derived peptides 9R, 9S1R and 124R on the NCI-60 panel and normal cell lines

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Abdelkrim Alileche, Greg Hampikian

An analysis of 97 previously diagnosed de novo adult acute erythroid leukemia patients following the 2016 revision to World Health Organization classification

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Shaowei Qiu, Erlie Jiang, Hui Wei, Dong Lin, Guangji Zhang, Shuning Wei, Chunlin Zhou, Kaiqi Liu, Ying Wang, Bingcheng Liu, Yuntao Liu, Benfa Gong, Xiaoyuan Gong, Sizhou Feng, Yingchang Mi, Mingzhe Han, Jianxiang Wang

Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification

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Doo-Yi Oh, Kyungsoo Jung, Ji-Young Song, Seokhwi Kim, Sang Shin, Yong-Jun Kwon, Ensel Oh, Woong-Yang Park, Sang Yong Song, Yoon-La Choi

Prognostic significance of BRAF and NRAS mutations in melanoma: a German study from routine care

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Markus V. Heppt, Timo Siepmann, Jutta Engel, Gabriele Schubert-Fritschle, Renate Eckel, Laura Mirlach, Thomas Kirchner, Andreas Jung, Anja Gesierich, Thomas Ruzicka, Michael J. Flaig, Carola Berking

Oncological outcomes in an Australian cohort according to the new prostate cancer grading groupings

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K. R. Beckmann, A. D. Vincent, M. E. O’Callaghan, P. Cohen, S. Chang, M. Borg, S. M. Evans, D. M. Roder, K. L. Moretti

A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress

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Khaoula Ben Younes, Simon Body, Élodie Costé, Pierre-Julien Viailly, Hadjer Miloudi, Clémence Coudre, Fabrice Jardin, Fatma Ben Aissa-Fennira, Brigitte Sola

Angiopoietin-1 deficiency increases tumor metastasis in mice

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Iacovos P. Michael, Martina Orebrand, Marta Lima, Beatriz Pereira, Olga Volpert, Susan E. Quaggin, Marie Jeansson

A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells

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Zhor Senhaji Mouhri, Elliot Goodfellow, Bertrand Jean-Claude

Palliative external beam radiotherapy for the treatment of tumor bleeding in inoperable advanced gastric cancer

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Yun Hee Lee, Jeong Won Lee, Hong Seok Jang

Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer

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A. K. Pedersen, J. Mendes Lopes de Melo, N. Mørup, K. Tritsaris, S. F. Pedersen

Reducing the socioeconomic gradient in uptake of the NHS bowel cancer screening Programme using a simplified supplementary information leaflet: a cluster-randomised trial

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Samuel G. Smith, Jane Wardle, Wendy Atkin, Rosalind Raine, Lesley M. McGregor, Gemma Vart, Steve Morris, Stephen W. Duffy, Susan Moss, Allan Hackshaw, Stephen Halloran, Ines Kralj-Hans, Rosemary Howe, Julia Snowball, Graham Handley, Richard F. Logan, Sandra Rainbow, Steve Smith, Mary Thomas, Nicholas Counsell, Christian von Wagner

Prognostic value of pretreatment serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ratio and gamma glutamyltransferase (GGT) in patients with esophageal squamous cell carcinoma

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Hao Huang, Xue-Ping Wang, Xiao-Hui Li, Hao Chen, Xin Zheng, Jian-Hua Lin, Ting Kang, Lin Zhang, Pei-Song Chen

Endogenous controls of gene expression in N-methyl-N-nitrosourea-induced T-cell lymphoma in p53-deficient mice

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Xi Wu, Susu Liu, Jianjun Lyu, Shuya Zhou, Yanwei Yang, Chenfei Wang, Wenda Gu, Qin Zuo, Baowen Li, Changfa Fan

Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition

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Lucia Sommerova, Eva Ondrouskova, Borivoj Vojtesek, Roman Hrstka

Phase I dose-escalation study of pazopanib combined with bevacizumab in patients with metastatic renal cell carcinoma or other advanced tumors

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Sylvie Négrier, David Pérol, Rastislav Bahleda, Antoine Hollebecque, Etienne Chatelut, Helen Boyle, Philippe Cassier, Séverine Metzger, Ellen Blanc, Jean-Charles Soria, Bernard Escudier

Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

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• Study protocol

Stine Braendegaard Winther, Pia Österlund, Åke Berglund, Bengt Glimelius, Camilla Qvortrup, Halfdan Sorbye, Per Pfeiffer

Impact of new generation hormone-therapy on cognitive function in elderly patients treated for a metastatic prostate cancer: Cog-Pro trial protocol

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• Study protocol

Marie Lange, Heidi Laviec, Hélène Castel, Natacha Heutte, Alexandra Leconte, Isabelle Léger, Bénédicte Giffard, Aurélie Capel, Martine Dubois, Bénédicte Clarisse, Elodie Coquan, Frédéric Di Fiore, Sophie Gouérant, Philippe Bartélémy, Laure Pierard, Karim Fizazi, Florence Joly

Identification of cancer risk and associated behaviour: implications for social marketing campaigns for cancer prevention

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Rebecca Kippen, Erica James, Bernadette Ward, Penny Buykx, Ardel Shamsullah, Wendy Watson, Kathy Chapman

RNA-transfection of γ/δ T cells with a chimeric antigen receptor or an α/β T-cell receptor: a safer alternative to genetically engineered α/β T cells for the immunotherapy of melanoma

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Dennis C. Harrer, Bianca Simon, Shin-ichiro Fujii, Kanako Shimizu, Ugur Uslu, Gerold Schuler, Kerstin F. Gerer, Stefanie Hoyer, Jan Dörrie, Niels Schaft

Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) study: design of a randomized controlled trial

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• Study protocol

Jonna K. van Vulpen, Peter D. Siersema, Richard van Hillegersberg, Grard A. P. Nieuwenhuijzen, Ewout A. Kouwenhoven, Richard P. R. Groenendijk, Donald L. van der Peet, Eric J. Hazebroek, Camiel Rosman, Carlo C. G. Schippers, Elles Steenhagen, Petra H. M. Peeters, Anne M. May

Down-regulation of the tumour suppressor κ-opioid receptor predicts poor prognosis in hepatocellular carcinoma patients

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Dongtai Chen, Yonghua Chen, Yan Yan, Jiahao Pan, Wei Xing, Qiang Li, Weian Zeng

BiClamp® vessel-sealing device for open hepatic resection of malignant and benign liver tumours: a single-institution experience

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Yi-jun Zhao, Da-chen Zhou, Fu-bao Liu, Hong-chuan Zhao, Guo-bin Wang, Xiao-ping Geng

EMX2 gene expression predicts liver metastasis and survival in colorectal cancer

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Berk Aykut, Markus Ochs, Praveen Radhakrishnan, Adrian Brill, Hermine Höcker, Sandra Schwarz, Daniel Weissinger, Roland Kehm, Yakup Kulu, Alexis Ulrich, Martin Schneider

Active smoking and risk of breast cancer in a Danish nurse cohort study

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Zorana Jovanovic Andersen, Jeanette Therming Jørgensen, Randi Grøn, Elvira Vaclavik Brauner, Elsebeth Lynge

Prognostic impact of a new score using neutrophil-to-lymphocyte ratios in the serum and malignant pleural effusion in lung cancer patients

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Yong Seok Lee, Hae-Seong Nam, Jun Hyeok Lim, Jung Soo Kim, Yeonsook Moon, Jae Hwa Cho, Jeong-Seon Ryu, Seung Min Kwak, Hong Lyeol Lee

Prognostic significance of the total number of harvested lymph nodes for lymph node-negative gastric cancer patients

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Xin Ji, Zhao-De Bu, Zi-Yu Li, Ai-Wen Wu, Lian-Hai Zhang, Ji Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Shuang-Xi Li, Fei Shan, Zi-Yu Jia, Jia-Fu Ji

Ageing, exposure to pollution, and interactions between climate change and local seasons as oxidant conditions predicting incident hematologic malignancy at KINSHASA University clinics, Democratic Republic of CONGO (DRC)

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Mireille Solange Nganga Nkanga, Benjamin Longo-Mbenza, Oladele Vincent Adeniyi, Jacques Bikaula Ngwidiwo, Antoine Lufimbo Katawandja, Paul Roger Beia Kazadi, Alain Nganga Nzonzila

A parallel-group randomized clinical trial of individually tailored, multidisciplinary, palliative rehabilitation for patients with newly diagnosed advanced cancer: the Pal-Rehab study protocol

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Lise Nottelmann, Mogens Groenvold, Tove Bahn Vejlgaard, Morten Aagaard Petersen, Lars Henrik Jensen

Development of nomograms to predict axillary lymph node status in breast cancer patients

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Kai Chen, Jieqiong Liu, Shunrong Li, Lisa Jacobs

Vitamin D supplementation in cutaneous malignant melanoma outcome (ViDMe): a randomized controlled trial

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J. De Smedt, S. Van Kelst, V. Boecxstaens, M. Stas, K. Bogaerts, D. Vanderschueren, C. Aura, K. Vandenberghe, D. Lambrechts, P. Wolter, O. Bechter, A. Nikkels, T. Strobbe, G. Emri, V. Marasigan, M. Garmyn

Are heart toxicities in breast cancer patients important for radiation oncologists? A practice pattern survey in German speaking countries

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Marciana Nona Duma, Stefan Münch, Markus Oechsner, Stephanie Elisabeth Combs

The feasibility and benefit of a brief psychosocial intervention in addition to early palliative care in patients with advanced cancer to reduce depressive symptoms: a pilot randomized controlled clinical trial

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Thamires Monteiro do Carmo, Bianca Sakamoto Ribeiro Paiva, Cleyton Zanardo de Oliveira, Maria Salete de Angelis Nascimento, Carlos Eduardo Paiva

Clinical decision-making and health-related quality of life during first-line and maintenance therapy in patients with advanced non-small cell lung cancer (NSCLC): findings from a real-world setting

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Monika Sztankay, Johannes Maria Giesinger, August Zabernigg, Elisabeth Krempler, Georg Pall, Wolfgang Hilbe, Otto Burghuber, Maximilian Hochmair, Gerhard Rumpold, Stephan Doering, Bernhard Holzner

Country and regional variations in purchase prices for essential cancer medications

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Raphael E. Cuomo, Robert L. Seidman, Tim K. Mackey

Concurrent chemoradiotherapy with or without cetuximab for stage II to IVb nasopharyngeal carcinoma: a case–control study

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Yang Li, Qiu-Yan Chen, Lin-Quan Tang, Li-Ting Liu, Shan-Shan Guo, Ling Guo, Hao-Yuan Mo, Ming-Yuan Chen, Xiang Guo, Ka-Jia Cao, Chao-Nan Qian, Mu-Shen Zeng, Jin-Xin Bei, Jian-Yong Shao, Ying Sun, Jing Tan, Shuai Chen, Jun Ma, Chong Zhao, Hai-Qiang Mai

Predictors of high healthcare costs in elderly patients with liver cancer in end-of-life: a longitudinal population-based study

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Jui-Kun Chiang, Yee-Hsin Kao

Erratum to: Identification of endonuclease domain-containing 1 as a novel tumor suppressor in prostate cancer

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• Erratum

Jianguang Qiu, Shubin Peng, Jie Si-Tu, Cheng Hu, Wentao Huang, Yunhua Mao, Wenhan Qiu, Ke Li, Dejuan Wang

Childhood cancer incidence by ethnic group in England, 2001–2007: a descriptive epidemiological study

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Shameq Sayeed, Isobel Barnes, Raghib Ali

Skeletal muscle depletion during chemotherapy has a large impact on physical function in elderly Japanese patients with advanced non–small-cell lung cancer

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Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori, Kazuhisa Nakashima, Masahiro Endo, Katsuhiro Omae, Keita Mori, Nobuyuki Yamamoto, Akira Tanuma, Toshiaki Takahashi

Urokinase-type plasminogen activator receptor (uPAR), tissue factor (TF) and epidermal growth factor receptor (EGFR): tumor expression patterns and prognostic value in oral cancer

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Anders Christensen, Katalin Kiss, Giedrius Lelkaitis, Karina Juhl, Morten Persson, Birgitte Wittenborg Charabi, Jann Mortensen, Julie Lyng Forman, Anne Lyngholm Sørensen, David Hebbelstrup Jensen, Andreas Kjaer, Christian von Buchwald

Comparison of PSA value at last follow-up of patients who underwent low-dose rate brachytherapy and intensity-modulated radiation therapy for prostate cancer

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Nobumichi Tanaka, Isao Asakawa, Yasushi Nakai, Makito Miyake, Satoshi Anai, Tomomi Fujii, Masatoshi Hasegawa, Noboru Konishi, Kiyohide Fujimoto

Docetaxel, Cisplatin, and 5-fluorouracil (DCF) chemotherapy in the treatment of metastatic or unresectable locally recurrent anal squamous cell carcinoma: a phase II study of French interdisciplinary GERCOR and FFCD groups (Epitopes-HPV02 study)

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Stefano Kim, Marine Jary, Thierry André, Véronique Vendrely, Bruno Buecher, Eric François, François-Clément Bidard, Sarah Dumont, Emmanuelle Samalin, Didier Peiffert, Simon Pernot, Nabil Baba-Hamed, Farid El Hajbi, Olivier Bouché, Jérôme Desrame, Aurélie Parzy, Mustapha Zoubir, Christophe Louvet, Jean-Baptiste Bachet, Thierry Nguyen, Meher Ben Abdelghani, Denis Smith, Christelle De La Fouchardière, Thomas Aparicio, Jaafar Bennouna, Jean-Marc Gornet, Marion Jacquin, Franck Bonnetain, Christophe Borg

The social and behavioral influences (SBI) study: study design and rationale for studying the effects of race and activation on cancer pain management

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Cezanne M. Elias, Cleveland G. Shields, Jennifer J. Griggs, Kevin Fiscella, Sharon L. Christ, Joseph Colbert, Stephen G. Henry, Beth G. Hoh, Haslyn E. R. Hunte, Mary Marshall, Supriya Gupta Mohile, Sandy Plumb, Mohamedtaki A. Tejani, Alison Venuti, Ronald M. Epstein

A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol

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• Study protocol

Jacek Hajda, Monika Lehmann, Ottheinz Krebs, Meinhard Kieser, Karsten Geletneky, Dirk Jäger, Michael Dahm, Bernard Huber, Tilman Schöning, Oliver Sedlaczek, Albrecht Stenzinger, Niels Halama, Volker Daniel, Barbara Leuchs, Assia Angelova, Jean Rommelaere, Christine E. Engeland, Christoph Springfeld, Guy Ungerechts

Population-based colorectal cancer screening programmes using a faecal immunochemical test: should faecal haemoglobin cut-offs differ by age and sex?

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Eunate Arana-Arri, Isabel Idigoras, Begoña Uranga, Raquel Pérez, Ana Irurzun, Iñaki Gutiérrez-Ibarluzea, Callum G. Fraser, Isabel Portillo, José Luis Hurtado, Carmen de No, Carlos Enciso, Maite Escalante, Begoña Atarés, José Javier Aguirre, Esther Pereda, Edurne Marañón, Pedro Otazua, María Fernández, José Francisco Egido, Eva Zapata, Leire Zubiaurre, Juana Mari Rodríguez, Pedro Esteban Sampedro, Marisa Goyeneche, José María Arrinda, Mari Luz Jauregui, Marta Gómez, Marta Saiz, Luis Bujanda, Inés Gil, Isabel Montalvo, José Miguel Larzabal, Maddi Garmendia, Fernando Izquierdo, Francisco Javier Fernández, Iago Rodríguez, Alain Huerta, Eduardo de Miguel, Inmaculada Barredo, Fidencio Bao, Anaiansi Hernández, Isabel Rodriguez, María José Fernández-Landa, María Imaz, Angel Calderón, Francisco Polo, Nagore Arbide, Gaspar Lantarón, Cristina Quesada, Itziar Marzana, Enrique Ojembarrena, Haritz Cortés, Iñaki Casado, Manuel Zaballa, Mar Ramírez, Amaia Aperribay, Cristian Amezaga, Lorea Martínez-Indart, Iraide Indart, Ariane Imaz-Ayo, Natale Imaz-Ayo, María José Fernández-Landa, Marta de la Cruz, Joseba Bidaurrazaga, Nerea Muniozguren, Nerea Larrañaga, Covadonga Audicana, Isabel Bilbao, José Luis Bilbao, Eduardo Millán, Saloa Unanue, Nere Mendizábal, Carlos Saiz, Santiago Rodríguez

Temporal influence of endocrine therapy with tamoxifen and chemotherapy on nutritional risk and obesity in breast cancer patients

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Mariana Tavares Miranda Lima, Kamila Pires de Carvalho, Fernanda Silva Mazzutti, Marcelo de Almeida Maia, Paula Philbert Lajolo Canto, Carlos Eduardo Paiva, Yara Cristina de Paiva Maia

Rare triad of periampullary carcinoid, duodenal gastrointestinal stromal tumor and plexiform neurofibroma at hepatic hilum in neurofibromatosis type 1: a case report

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• Case report

Nihed Abdessayed, Rahul Gupta, Sarra Mestiri, Ahlem Bdioui, Mounir Trimech, Moncef Mokni

Distinct preoperative clinical features predict four histopathological subtypes of high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum

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Takuma Ohsuga, Ken Yamaguchi, Aki Kido, Ryusuke Murakami, Kaoru Abiko, Junzo Hamanishi, Eiji Kondoh, Tsukasa Baba, Ikuo Konishi, Noriomi Matsumura

Adherence and feasibility of 2 treatment schedules of S-1 as adjuvant chemotherapy for patients with completely resected advanced lung cancer: a multicenter randomized controlled trial

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Yoshinobu Hata, Takaharu Kiribayashi, Kazuma Kishi, Makoto Nagashima, Takefumi Nakayama, Shingo Ikeda, Mitsutaka Kadokura, Yuichi Ozeki, Hajime Otsuka, Yoshitaka Murakami, Keigo Takagi, Akira Iyoda

Propensity score matching analysis of a phase II study on simultaneous modulated accelerated radiation therapy using helical tomotherapy for nasopharyngeal carcinomas

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Lei Du, Xin-Xin Zhang, Lin-Chun Feng, Bao-Lin Qu, Jing Chen, Jun Yang, Hai-Xia Liu, Shou-Ping Xu, Chuan-Bin Xie, Lin Ma

Prognostic significance of E-cadherin and N-cadherin expression in Gliomas

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Myung-Giun Noh, Se-Jeong Oh, Eun-Jung Ahn, Yeong-Jin Kim, Tae-Young Jung, Shin Jung, Kyung-Keun Kim, Jae-Hyuk Lee, Kyung-Hwa Lee, Kyung-Sub Moon

Presence of immune cells, low tumor proliferation and wild type BRAF mutation status is associated with a favourable clinical outcome in stage III cutaneous melanoma

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Johan Falkenius, Hemming Johansson, Rainer Tuominen, Marianne Frostvik Stolt, Johan Hansson, Suzanne Egyhazi Brage

Prostate cancer-specific survival among warfarin users in the Finnish Randomized Study of Screening for Prostate Cancer

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Pete T. T. Kinnunen, Teemu J. Murtola, Kirsi Talala, Kimmo Taari, Teuvo L. J. Tammela, Anssi Auvinen

Prognosis and treatment of FOLFOX therapy related interstitial pneumonia: a plea for multimodal immune modulating therapy in the respiratory insufficient patient

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• Case report

Annick De Weerdt, Amélie Dendooven, Annemie Snoeckx, Jan Pen, Martin Lammens, Philippe G. Jorens

Cancer incidence in eastern Morocco: cancer patterns and incidence trends, 2005–2012

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Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, Meryem Ouarzane, Redouane Boulouiz, Mohammed Bellaoui

Tumoral LINE-1 hypomethylation is associated with poor survival of patients with intrahepatic cholangiocarcinoma

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Seorin Jeong, Kyoungbun Lee, Xianyu Wen, Younghoon Kim, Nam-Yun Cho, Ja-June Jang, Gyeong Hoon Kang

Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer

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Yuji Yamashita, Shin Nishiumi, Seishi Kono, Shintaro Takao, Takeshi Azuma, Masaru Yoshida

Is neuron-specific enolase useful for diagnosing malignant pleural effusions? evidence from a validation study and meta-analysis

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Jing Zhu, Mei Feng, Liqun Liang, Ni Zeng, Chun Wan, Ting Yang, Yongchun Shen, Fuqiang Wen

D-dimer levels and cerebral infarction in critically ill cancer patients

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Jeong-Am Ryu, Oh Young Bang, Geun-Ho Lee

EGFR copy number alterations in primary tumors, metastatic lymph nodes, and recurrent and multiple primary tumors in oral cavity squamous cell carcinoma

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Shiang-Fu Huang, Huei-Tzu Chien, Sou-De Cheng, Wen-Yu Chuang, Chun-Ta Liao, Hung-Ming Wang

VEGFR2 regulates endothelial differentiation of colon cancer cells

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Zhiyong Liu, Lisha Qi, Yixian Li, Xiulan Zhao, Baocun Sun

Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential

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Jessica G. Tong, Yudith Ramos Valdes, Milani Sivapragasam, John W. Barrett, John C. Bell, David Stojdl, Gabriel E. DiMattia, Trevor G. Shepherd

Innovative dressing and securement of tunneled central venous access devices in pediatrics: a pilot randomized controlled trial

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Amanda J. Ullman, Tricia Kleidon, Victoria Gibson, Craig A. McBride, Gabor Mihala, Marie Cooke, Claire M. Rickard

Divergent trends in lung cancer incidence by gender, age and histological type in Estonia: a nationwide population-based study

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Tiiu Aareleid, Mari-Liis Zimmermann, Aleksei Baburin, Kaire Innos

Cancer-related risk factors and incidence of major cancers by race, gender and region; analysis of the NIH-AARP diet and health study

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Tomi Akinyemiju, Howard Wiener, Maria Pisu

Chemoradiotherapy versus surgery followed by postoperative radiotherapy in tonsil cancer: Korean Radiation Oncology Group (KROG) study

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Sanghyuk Song, Hong-Gyun Wu, Chang Geol Lee, Ki Chang Keum, Mi Sun Kim, Yong Chan Ahn, Dongryul Oh, Hyo Jung Park, Sang-Wook Lee, Geumju Park, Sung Ho Moon, Kwan Ho Cho, Yeon-Sil Kim, Yongkyun Won, Young-Taek Oh, Won-Taek Kim, Jae-Uk Jeong

Self-reported sexual health: Breast cancer survivors compared to women from the general population – an observational study

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Anne Oberguggenberger, Caroline Martini, Nathalie Huber, Lesley Fallowfield, Michael Hubalek, Martin Daniaux, Barbara Sperner-Unterweger, Bernhard Holzner, Monika Sztankay, Eva Gamper, Verena Meraner

Factors related with colorectal and stomach cancer screening practice among disease-free lung cancer survivors in Korea

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Sang Min Park, Jongmog Lee, Young Ae Kim, Yoon Jung Chang, Moon Soo Kim, Young Mog Shim, Jae Ill Zo, Young Ho Yun

LINE-1 hypermethylation in white blood cell DNA is associated with high-grade cervical intraepithelial neoplasia

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Martina Barchitta, Annalisa Quattrocchi, Andrea Maugeri, Carolina Canto, Nadia La Rosa, Maria Antonietta Cantarella, Giuseppa Spampinato, Aurora Scalisi, Antonella Agodi

Comprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy

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Talal Hilal, Mary Nakazawa, Jacob Hodskins, John L. Villano, Aju Mathew, Guarav Goel, Lars Wagner, Susanne M. Arnold, Philip DeSimone, Lowell B. Anthony, Peter J. Hosein

Development of quality indicators for non-small cell lung cancer care: a first step toward assessing and improving quality of cancer care in China

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Xinyu Wang, Shaofei Su, Shouyi Li, Han Bao, Meiqi Zhang, Dan Liu, Hao Jiang, Jiaying Wang, Meina Liu

Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer

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Shinichiro Kashiwagi, Wakaba Fukushima, Yuka Asano, Wataru Goto, Koji Takada, Satoru Noda, Tsutomu Takashima, Naoyoshi Onoda, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira

NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity

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Qijiong Li, Xiaofeng Liu, Kemin Jin, Min Lu, Chunfeng Zhang, Xiaojuan Du, Baocai Xing

Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis

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Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Yan Wang, Thomas H. Y. Leung, Stephanie S. Liu, Annie N. Y. Cheung, Hextan Y. S. Ngan

Down-regulation of miRNA-148a and miRNA-625-3p in colorectal cancer is associated with tumor budding

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Edita Baltruskeviciene, Diana Schveigert, Vaidotas Stankevicius, Ugnius Mickys, Tadas Zvirblis, Jaroslav Bublevic, Kestutis Suziedelis, Eduardas Aleknavicius

Effectiveness of PIVKA-II in the detection of hepatocellular carcinoma based on real-world clinical data

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Rentao Yu, Zhaoxia Tan, Xiaomei Xiang, Yunjie Dan, Guohong Deng

A change in the study evaluation paradigm reveals that larynx preservation compromises survival in T4 laryngeal cancer patients

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Gerhard Dyckhoff, Peter K. Plinkert, Heribert Ramroth

Downregulation of GPR155 as a prognostic factor after curative resection of hepatocellular carcinoma

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Shinichi Umeda, Mitsuro Kanda, Hiroyuki Sugimoto, Haruyoshi Tanaka, Masamichi Hayashi, Suguru Yamada, Tsutomu Fujii, Hideki Takami, Yukiko Niwa, Naoki Iwata, Chie Tanaka, Daisuke Kobayashi, Michitaka Fujiwara, Yasuhiro Kodera

Updating vital status by tracking in the community among patients with epidemic Kaposi sarcoma who are lost to follow-up in sub-Saharan Africa

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Aggrey Semeere, Esther Freeman, Megan Wenger, David Glidden, Mwebesa Bwana, Micheal Kanyesigye, Fredrick Chite Asirwa, Elyne Rotich, Naftali Busakhala, Emmanuel Oga, Elima Jedy-Agba, Vivian Kwaghe, Kenneth Iregbu, Clement Adebamowo, Antoine Jaquet, Francois Dabis, Sam Phiri, Julia Bohlius, Matthias Egger, Constantin T. Yiannoutsos, Kara Wools-Kaloustian, Jeffrey Martin

Uncommon presentation of a rare tumour - incidental finding in an asymptomatic patient: case report and comprehensive review of the literature on intrapericardial solitary fibrous tumours

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• Case report

Csilla Czimbalmos, Ibolya Csecs, Miklos Polos, Elektra Bartha, Nikolette Szucs, Attila Toth, Pal Maurovich-Horvat, David Becker, Zoltan Sapi, Zoltan Szabolcs, Bela Merkely, Hajnalka Vago

Adjuvant chemotherapy versus chemoradiotherapy for small cell lung cancer with lymph node metastasis: a retrospective observational study with use of a national database in Japan

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Hirokazu Urushiyama, Taisuke Jo, Hideo Yasunaga, Yasuhiro Yamauchi, Hiroki Matsui, Wakae Hasegawa, Hideyuki Takeshima, Yoshihisa Hiraishi, Akihisa Mitani, Kiyohide Fushimi, Takahide Nagase

Association between self-perception of aging, view of cancer and health of older patients in oncology: a one-year longitudinal study

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Sarah Schroyen, Pierre Missotten, Guy Jerusalem, M. Van den Akker, F. Buntinx, Stéphane Adam

Role of adjuvant chemotherapy in locally advanced rectal cancer with ypT0-3N0 after preoperative chemoradiation therapy and surgery

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Chang Gon Kim, Joong Bae Ahn, Sang Joon Shin, Seung Hoon Beom, Su Jin Heo, Hyung Soon Park, Jee Hung Kim, Eun Ah Choe, Woong Sub Koom, Hyuk Hur, Byung Soh Min, Nam Kyu Kim, Hoguen Kim, Chan Kim, Inkyung Jung, Minkyu Jung

Trends in risk classification and primary therapy of Japanese patients with prostate cancer in Nara urological research and treatment group (NURTG) – comparison between 2004–2006, 2007–2009, and 2010–2012

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Nobumichi Tanaka, Yasushi Nakai, Makito Miyake, Satoshi Anai, Takeshi Inoue, Tomomi Fujii, Noboru Konishi, Kiyohide Fujimoto

Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133+/EpCAM+ phenotype: a promising target for preventing progression of TNBC

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Federica Brugnoli, Silvia Grassilli, Paola Lanuti, Marco Marchisio, Yasamin Al-Qassab, Federica Vezzali, Silvano Capitani, Valeria Bertagnolo

Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma

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Basile Tessier-Cloutier, Steve E. Kalloger, Mohammad Al-Kandari, Katy Milne, Dongxia Gao, Brad H. Nelson, Daniel J. Renouf, Brandon S. Sheffield, David F. Schaeffer

3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation

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Xiaoli Peng, Hui Chang, Junli Chen, Qianyong Zhang, Xiaoping Yu, Mantian Mi

CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population

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Sanna Hallamies, Liisa M. Pelttari, Paula Poikonen-Saksela, Antti Jekunen, Arja Jukkola-Vuorinen, Päivi Auvinen, Carl Blomqvist, Kristiina Aittomäki, Johanna Mattson, Heli Nevanlinna

Stress alters the expression of cancer-related genes in the prostate

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Ivan E. Flores, Jorge A. Sierra-Fonseca, Olinamyr Davalos, Luis A. Saenz, Maria M. Castellanos, Jaidee K. Zavala, Kristin L. Gosselink

Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes

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Suguru Yamauchi, Boya Zhong, Kiyoko Kawamura, Shan Yang, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa

A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America

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Benedito Mauro Rossi, Edenir Inêz Palmero, Francisco López-Kostner, Carlos Sarroca, Carlos Alberto Vaccaro, Florencia Spirandelli, Patricia Ashton-Prolla, Yenni Rodriguez, Henrique de Campos Reis Galvão, Rui Manuel Reis, André Escremim de Paula, Luis Gustavo Capochin Romagnolo, Karin Alvarez, Adriana Della Valle, Florencia Neffa, Pablo German Kalfayan, Enrique Spirandelli, Sergio Chialina, Melva Gutiérrez Angulo, Maria del Carmen Castro-Mujica, Julio Sanchez de Monte, Richard Quispe, Sabrina Daniela da Silva, Norma Teresa Rossi, Claudia Barletta-Carrillo, Susana Revollo, Ximena Taborga, L. Lena Morillas, Hélène Tubeuf, Erika Maria Monteiro-Santos, Tamara Alejandra Piñero, Constantino Dominguez-Barrera, Patrik Wernhoff, Alexandra Martins, Eivind Hovig, Pål Møller, Mev Dominguez-Valentin

The association between smoking and breast cancer characteristics and outcome

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Hadar Goldvaser, Omer Gal, Shulamith Rizel, Daniel Hendler, Victoria Neiman, Tzippy Shochat, Aaron Sulkes, Baruch Brenner, Rinat Yerushalmi

Circadian disruption promotes tumor growth by anabolic host metabolism; experimental evidence in a rat model

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Natalí N. Guerrero-Vargas, Raful Navarro-Espíndola, Mara A. Guzmán-Ruíz, María del Carmen Basualdo, Estefania Espitia-Bautista, Ana López-Bago, Ricardo Lascurain, Cinthya Córdoba-Manilla, Ruud M. Buijs, Carolina Escobar

ERp29 controls invasion and metastasis of gastric carcinoma by inhibition of epithelial-mesenchymal transition via PI3K/Aktsignaling pathway

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Jianxin Ye, Jinsheng Huang, Jie Xu, Qiang Huang, Jinzhou Wang, Wenjing Zhong, Xinjian Lin, Yun Li, Xu Lin

Prognostic consequences of implementing cancer patient pathways in Denmark: a comparative cohort study of symptomatic cancer patients in primary care

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Henry Jensen, Marie Louise Tørring, Peter Vedsted

Development and external validation of nomograms to predict the risk of skeletal metastasis at the time of diagnosis and skeletal metastasis-free survival in nasopharyngeal carcinoma

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Lin Yang, Liangping Xia, Yan Wang, Shasha He, Haiyang Chen, Shaobo Liang, Peijian Peng, Shaodong Hong, Yong Chen

The values of neutrophil-lymphocyte ratio and/or prostate-specific antigen in discriminating real Gleason score ≥ 7 prostate cancer from group of biopsy-based Gleason score ≤ 6

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Hanfeng Wang, Liangyou Gu, Yongjie Wu, Dan Feng, Junyao Duan, Xiaocong Wang, Yong Huang, Shengpan Wu, Jianwen Chen, Guangda Luo, Xu Zhang

Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells

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Håkon Reikvam, Randi Hovland, Rakel Brendsdal Forthun, Sigrid Erdal, Bjørn Tore Gjertsen, Hanne Fredly, Øystein Bruserud

Positive regulation of prostate cancer cell growth by lipid droplet forming and processing enzymes DGAT1 and ABHD5

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Ranjana Mitra, Thuc T. Le, Priyatham Gorjala, Oscar B. Goodman Jr.

Reduced ovarian reserve in young early breast cancer patients: preliminary data from a prospective cohort trial

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Antonia Wenners, Jana Grambach, Juliane Koss, Nicolai Maass, Walter Jonat, Andreas Schmutzler, Christoph Mundhenke

Extranodal natural killer/T-cell lymphoma in Malawi: a report of three cases

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Tamiwe Tomoka, Eric Powers, Toon van der Gronde, Amy Amuquandoh, Bal Mukunda Dhungel, Coxcilly Kampani, Steve Kamiza, Nathan D. Montgomery, Yuri Fedoriw, Satish Gopal

Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer

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Annelies Gonnissen, Sofie Isebaert, Christiaan Perneel, Chad M. McKee, Clare Verrill, Richard J. Bryant, Filip Van Utterbeeck, Evelyne Lerut, Karin Haustermans, Ruth J. Muschel

Testosterone inhibits the growth of prostate cancer xenografts in nude mice

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Weitao Song, Vikram Soni, Samit Soni, Mohit Khera

IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer

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Yann Neuzillet, Elodie Chapeaublanc, Clémentine Krucker, Leanne De Koning, Thierry Lebret, François Radvanyi, Isabelle Bernard-Pierrot

New use of low-dose aspirin and risk of colorectal cancer by stage at diagnosis: a nested case–control study in UK general practice

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Luis A. García Rodríguez, Montse Soriano-Gabarró, Susan Bromley, Angel Lanas, Lucía Cea Soriano

Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors

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Charles-André Philip, Ido Laskov, Marie-Claude Beauchamp, Maud Marques, Oreekha Amin, Joanna Bitharas, Roy Kessous, Liron Kogan, Tahira Baloch, Walter H. Gotlieb, Amber Yasmeen

Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment

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Yang An, Shuzhen Wang, Songlin Li, Lulu Zhang, Dayong Wang, Haojie Wang, Shibai Zhu, Wan Zhu, Yongqiang Li, Wenwu Chen, Shaoping Ji, Xiangqian Guo

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis

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Azhar R. Hussain, Abdul Khalid Siraj, Maqbool Ahmed, Rong Bu, Poyil Pratheeshkumar, Alanood M. Alrashed, Zeeshan Qadri, Dahish Ajarim, Fouad Al-Dayel, Shaham Beg, Khawla S. Al-Kuraya

BRCA2 carriers with male breast cancer show elevated tumour methylation

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Siddhartha Deb, Kylie L. Gorringe, Jia-Min B. Pang, David J. Byrne, Elena A. Takano, kConFab Investigators, Alexander Dobrovic, Stephen B. Fox

Involvement of DPP9 in gene fusions in serous ovarian carcinoma

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Marianne Lislerud Smebye, Antonio Agostini, Bjarne Johannessen, Jim Thorsen, Ben Davidson, Claes Göran Tropé, Sverre Heim, Rolf Inge Skotheim, Francesca Micci

Neutrophil-lymphocyte ratio complements volumetric staging as prognostic factor in patients treated with definitive radiotherapy for oropharyngeal cancer

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Cédric Panje, Oliver Riesterer, Christoph Glanzmann, Gabriela Studer

Integrator complex subunit 6 (INTS6) inhibits hepatocellular carcinoma growth by Wnt pathway and serve as a prognostic marker

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Ka Yin Lui, Hui Zhao, Chunhui Qiu, Chuo Li, Zhigang Zhang, Haoran Peng, Rongdang Fu, Hu-an Chen, Min-qiang Lu

The safety and efficacy of transarterial chemoembolization combined with sorafenib and sorafenib mono-therapy in patients with BCLC stage B/C hepatocellular carcinoma

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Fei-Xiang Wu, Jie Chen, Tao Bai, Shao-Liang Zhu, Tian-Bo Yang, Lu-Nan Qi, Ling Zou, Zi-Hui Li, Jia-Zhou Ye, Le-Qun Li

A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer

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Kerry Lynn Reynolds, Philippe L. Bedard, Se-Hoon Lee, Chia-Chi Lin, Josep Tabernero, Maria Alsina, Ezra Cohen, José Baselga, George Blumenschein Jr, Donna M. Graham, Ignacio Garrido-Laguna, Dejan Juric, Sunil Sharma, Ravi Salgia, Abdelkader Seroutou, Xianbin Tian, Rose Fernandez, Alex Morozov, Qing Sheng, Thiruvamoor Ramkumar, Angela Zubel, Yung-Jue Bang

Can you un-ring the bell? A qualitative study of how affect influences cancer screening decisions

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S. Michelle Driedger, Gary Annable, Melissa Brouwers, Donna Turner, Ryan Maier

FOXP3 Is a HCC suppressor gene and Acts through regulating the TGF-β/Smad2/3 signaling pathway

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Jie-Yi Shi, Li-Jie Ma, Ji-Wei Zhang, Meng Duan, Zhen-Bin Ding, Liu-Xiao Yang, Ya Cao, Jian Zhou, Jia Fan, Xiaoming Zhang, Ying-Jun Zhao, Xiao-Ying Wang, Qiang Gao

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter study

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Bernies van der Hiel, John B.A.G. Haanen, Marcel P.M. Stokkel, Daniel S. Peeper, Connie R. Jimenez, Jos H. Beijnen, Bart A. van de Wiel, Ronald Boellaard, Alfons J.M. van den Eertwegh

Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells

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Anja Reithmeier, Elena Panizza, Michael Krumpel, Lukas M. Orre, Rui M. M. Branca, Janne Lehtiö, Barbro Ek-Rylander, Göran Andersson

The outcome of prostate cancer patients treated with curative intent strongly depends on survival after metastatic progression

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Mariarosa Pascale, Che Ngwa Azinwi, Barbara Marongiu, Gianfranco Pesce, Flavio Stoffel, Enrico Roggero

Analysis of B7-H4 expression in metastatic pleural adenocarcinoma and therapeutic potential of its antagonists

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Cheng Chen, Qiu-Xia Qu, Fang Xie, Wei-Dong Zhu, Ye-Han Zhu, Jian-An Huang

Access to clinical trials among oncology patients: results of a cross sectional survey

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Mariko Carey, Allison W. Boyes, Rochelle Smits, Jamie Bryant, Amy Waller, Ian Olver

Aesthetic principles access thyroidectomy produces the best cosmetic outcomes as assessed using the patient and observer scar assessment scale

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Xiao Ma, Qi-jun Xia, Guojun Li, Tian-xiao Wang, Qin Li

The suppressive role of miR-542-5p in NSCLC: the evidence from clinical data and in vivo validation using a chick chorioallantoic membrane model

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Rong-quan He, Xiao-jiao Li, Lu Liang, You Xie, Dian-zhong Luo, Jie Ma, Zhi-gang Peng, Xiao-hua Hu, Gang Chen

Follow-up care after treatment for prostate cancer: protocol for an evaluation of a nurse-led supported self-management and remote surveillance programme

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Jane Frankland, Hazel Brodie, Deborah Cooke, Claire Foster, Rebecca Foster, Heather Gage, Jake Jordan, Ines Mesa-Eguiagaray, Ruth Pickering, Alison Richardson

Association between tumour infiltrating lymphocytes, histotype and clinical outcome in epithelial ovarian cancer

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Fiona R. James, Mercedes Jiminez-Linan, Jennifer Alsop, Marie Mack, Honglin Song, James D. Brenton, Paul D. P. Pharoah, H. Raza Ali

MiR-9, miR-21, and miR-155 as potential biomarkers for HPV positive and negative cervical cancer

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Sunyoung Park, Kiyoon Eom, Jungho Kim, Hyeeun Bang, Hye-young Wang, Sungwoo Ahn, Geehyuk Kim, Hyoungsoon Jang, Sunghyun Kim, Dongsup Lee, Kwang Hwa Park, Hyeyoung Lee

Descriptive characteristics of prostate cancer in patients with a history of primary male breast cancer – a SEER analysis

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Nikita Abhyankar, Kent F. Hoskins, Michael R. Abern, Gregory S. Calip

Intravital imaging of metastasis in adult Zebrafish

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David C. Benjamin, Richard O. Hynes

Clusterin modulates transdifferentiation of non-small-cell lung cancer

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Runsen Jin, Xingshi Chen, Dingpei Han, Xiaoying Luo, Hecheng Li

Assessment of Ki67 and uPA/PAI-1 expression in intermediate-risk early stage breast cancers

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Elise Deluche, Laurence Venat-Bouvet, Sophie Leobon, Veronique Fermeaux, Joelle Mollard, Nadira Saidi, Isabelle Jammet, Yves Aubard, Nicole Tubiana-Mathieu

Benefits of home-based multidisciplinary exercise and supportive care in inoperable non-small cell lung cancer – protocol for a phase II randomised controlled trial

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Lara Edbrooke, Sanchia Aranda, Catherine L. Granger, Christine F. McDonald, Mei Krishnasamy, Linda Mileshkin, Louis Irving, Sabine Braat, Ross A. Clark, Ian Gordon, Linda Denehy

TrueNTH sexual recovery study protocol: a multi-institutional collaborative approach to developing and testing a web-based intervention for couples coping with the side-effects of prostate cancer treatment in a randomized controlled trial

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D. Wittmann, A. Mehta, L. Northouse, R. Dunn, T. Braun, A. Duby, L. An, L. Arab, R. Bangs, S. Bober, J. Brandon, M. Coward, M. Dunn, M. Galbraith, M. Garcia, J. Giblin, M. Glode, B. Koontz, A. Lowe, S. Mitchell, J. Mulhall, C. Nelson, K. Paich, C. Saigal, T. Skolarus, J. Stanford, T. Walsh, C. E. Pollack

Whole-lesion apparent diffusion coefficient histogram analysis: significance in T and N staging of gastric cancers

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Song Liu, Yujuan Zhang, Ling Chen, Wenxian Guan, Yue Guan, Yun Ge, Jian He, Zhengyang Zhou

Correction to: Tumor-suppressive effects of atelocollagen-conjugated hsa-miR-520d-5p on un-differentiated cancer cells in a mouse xenograft model

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Yoshitaka Ishihara, Satoshi Tsuno, Satoshi Kuwamoto, Taro Yamashita, Yusuke Endo, Keigo Miura, Yugo Miura, Takemasa Sato, Junichi Hasegawa, Norimasa Miura

Correction to: iCanADAPT early protocol: randomised controlled trial (RCT) of clinician supervised transdiagnostic internet-delivered cognitive behaviour therapy (iCBT) for depression and/or anxiety in early stage cancer survivors -vs- treatment as usual

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M. J. Murphy, J. M. Newby, P. Butow, L. Kirsten, K. Allison, S. Loughnan, M. A. Price, J. Shaw, H. Shepherd, J. Smith, G. Andrews

Correction to: Hospital discharges for fever and neutropenia in pediatric cancer patients: United States, 2009

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Emily L. Mueller, Kelly J. Walkovich, Rajen Mody, Achamyeleh Gebremariam, Matthew M. Davis

Correction to: Circulating blood levels of IL-6, IFN-γ, and IL-10 as potential diagnostic biomarkers in gastric cancer: a controlled study

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Norma Sánchez-Zauco, Javier Torres, Alejandro Gómez, Margarita Camorlinga-Ponce, Leopoldo Muñoz-Pérez, Roberto Herrera-Goepfert, Rafael Medrano-Guzmán, Silvia Giono-Cerezo, Carmen Maldonado-Bernal

Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer

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Han Hee Lee, Sung Hak Lee, Kyo Young Song, Sae Jung Na, Joo Hyun O, Jae Myung Park, Eun Sun Jung, Myung-Gyu Choi, Cho Hyun Park

Respiratory-gated (4D) contrast-enhanced FDG PET-CT for radiotherapy planning of lower oesophageal carcinoma: feasibility and impact on planning target volume

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Andrew Scarsbrook, Gillian Ward, Patrick Murray, Rebecca Goody, Karen Marshall, Garry McDermott, Robin Prestwich, Ganesh Radhakrishna

Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers

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Samantha S. Dykes, Joshua J. Steffan, James A. Cardelli

MiR-216b inhibits cell proliferation by targeting FOXM1 in cervical cancer cells and is associated with better prognosis

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Shanyang He, Bing Liao, Yalan Deng, Chang Su, Jiuling Tuo, Jun Liu, Shuzhong Yao, Lin Xu

Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study)

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Hiromichi Matsuoka, Junji Tsurutani, Yasutaka Chiba, Yoshihiko Fujita, Masato Terashima, Takeshi Yoshida, Kiyohiro Sakai, Yoichi Otake, Atsuko Koyama, Kazuto Nishio, Kazuhiko Nakagawa

Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin

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Silje Haukali Omland, Erika Elgstrand Wettergren, Sarah Mollerup, Maria Asplund, Tobias Mourier, Anders Johannes Hansen, Robert Gniadecki

Productivity losses and public finance burden attributable to breast cancer in Poland, 2010–2014

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Błażej Łyszczarz, Ewelina Nojszewska

Enzalutamide versus abiraterone as a first-line endocrine therapy for castration-resistant prostate cancer (ENABLE study for PCa): a study protocol for a multicenter randomized phase III trial

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Kouji Izumi, Atsushi Mizokami, Mikio Namiki, Shogo Inoue, Nobumichi Tanaka, Yuko Yoshio, Kei Ishibashi, Manabu Kamiyama, Noriyasu Kawai, Hideki Enokida, Takashi Shima, Shizuko Takahara

The prognostic value of pretreatment tumor apparent diffusion coefficient values in nasopharyngeal carcinoma

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Dan-Fang Yan, Wen-Bao Zhang, Shan-Bao Ke, Feng Zhao, Sen-Xiang Yan, Qi-Dong Wang, Li-Song Teng

Dilemmas in a pregnant woman with myelofibrosis secondary to signet ring adenocarcinoma: a case report

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Pujun Guan, Zihang Chen, Li Zhang, Ling Pan

The XRCC 1 DNA repair gene modifies the environmental risk of stomach cancer: a hospital-based matched case-control study

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Nuntiput Putthanachote, Supannee Promthet, Cameron Hurst, Krittika Suwanrungruang, Peechanika Chopjitt, Surapon Wiangnon, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Tony Hsiu-Hsi Chen

Higher educational attainment associated with reduced likelihood of abnormal cervical lesions among Zambian women - a cross sectional study

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Twaambo Euphemia Hamoonga, Rosemary Ndonyo Likwa, Patrick Musonda, Charles Michelo

Cancer incidence in Germany attributable to human papillomavirus in 2013

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Nina Buttmann-Schweiger, Yvonne Deleré, Stefanie J. Klug, Klaus Kraywinkel

A single-arm phase II study of nab-paclitaxel for patients with chemorefractory non-small cell lung cancer

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Hisashi Tanaka, Kageaki Taima, Takeshi Morimoto, Yoshihito Tanaka, Masamichi Itoga, Kunihiko Nakamura, Akihito Hayashi, Mika Kumagai, Hideo Yasugahira, Megumi Mikuniya, Koichi Okudera, Shingo Takanashi, Sadatomo Tasaka

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

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Wayne J. Aston, Danika E. Hope, Anna K. Nowak, Bruce W. Robinson, Richard A. Lake, W. Joost Lesterhuis

Personalized treatment of women with early breast cancer: a risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and Adjuvant!Online

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Beate Jahn, Ursula Rochau, Christina Kurzthaler, Michael Hubalek, Rebecca Miksad, Gaby Sroczynski, Mike Paulden, Marvin Bundo, David Stenehjem, Diana Brixner, Murray Krahn, Uwe Siebert

Methodological study to evaluate the psychometric properties of FACIT-CD in a sample of Brazilian women with cervical intraepithelial neoplasia

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Cristiane Menezes Sirna Fregnani, José Humberto Tavares Guerreiro Fregnani, Adhemar Longatto-Filho

The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database

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Long Thanh Tran, Hang Thi Minh Lai, Chihaya Koriyama, Futoshi Uwatoko, Suminori Akiba

Epidemiology of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL) among a cohort of HIV-infected and uninfected Ghanaian women

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Dorcas Obiri-Yeboah, Patrick K. Akakpo, Mohamed Mutocheluh, Emmanuel Adjei-Danso, Gloria Allornuvor, Daniel Amoako-Sakyi, Yaw Adu-Sarkodie, Philippe Mayaud

Societal preferences for adjuvant melanoma health states: UK and Australia

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Mark R. Middleton, Michael B. Atkins, Kaitlan Amos, Peter Feng Wang, Srividya Kotapati, Javier Sabater, Kathleen Beusterien

Clinicopathological and prognostic significance of programmed death ligand-1 expression in breast cancer: a meta-analysis

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Hye Min Kim, Jinae Lee, Ja Seung Koo

Cost-effectiveness analysis of XELOX versus XELOX plus bevacizumab for metastatic colorectal cancer in a public hospital school

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Andrea Queiróz Ungari, Leonardo Régis Leira Pereira, Altacílio Aparecido Nunes, Fernanda Maris Peria

Validity of self-reported breast cancer characteristics in a nationwide cohort of women with a family history of breast cancer

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Aimee A. D’Aloisio, Hazel B. Nichols, M. Elizabeth Hodgson, Sandra L. Deming-Halverson, Dale P. Sandler

Exercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses

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George A. Kelley, Kristi S. Kelley

Isolation and characterization of three new anti-proliferative Sesquiterpenes from Polygonum barbatum and their mechanism via apoptotic pathway

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Umar Farooq, Sadia Naz, Binte Zehra, Ajmal Khan, Syed Abid Ali, Ayaz Ahmed, Rizwana Sarwar, Syed Majid Bukhari, Abdur Rauf, Izhar Ahmad, Yahia Nasser Mabkhot

18F- FDG PET/CT helps differentiate autoimmune pancreatitis from pancreatic cancer

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Jian Zhang, Guorong Jia, Changjing Zuo, Ningyang Jia, Hui Wang

Whether intermediate-risk stage 1A, grade 1/2, endometrioid endometrial cancer patients with lesions larger than 2 cm warrant lymph node dissection?

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Menghan Zhu, Nan Jia, Feifei Huang, Xiaoxia Liu, Yuqing Zhao, Xiang Tao, Wei Jiang, Qin Li, Weiwei Feng

The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review

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Ian A. Cree, Lesley Uttley, Helen Buckley Woods, Hugh Kikuchi, Anne Reiman, Susan Harnan, Becky L. Whiteman, Sian Taylor Philips, Michael Messenger, Angela Cox, Dawn Teare, Orla Sheils, Jacqui Shaw

GRcalculator: an online tool for calculating and mining dose–response data

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Nicholas A. Clark, Marc Hafner, Michal Kouril, Elizabeth H. Williams, Jeremy L. Muhlich, Marcin Pilarczyk, Mario Niepel, Peter K. Sorger, Mario Medvedovic

The relative risk of second primary cancers in Austria’s western states: a retrospective cohort study

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Oliver Preyer, Nicole Concin, Andreas Obermair, Hans Concin, Hanno Ulmer, Willi Oberaigner

Psychological distress, chronic conditions and quality of life in elderly hematologic cancer patients: study protocol of a prospective study

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Norbert Köhler, Anja Mehnert, Heide Götze

Postdiagnostic physical activity, sleep duration, and TV watching and all-cause mortality among long-term colorectal cancer survivors: a prospective cohort study

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Ilka Ratjen, Clemens Schafmayer, Romina di Giuseppe, Sabina Waniek, Sandra Plachta-Danielzik, Manja Koch, Greta Burmeister, Ute Nöthlings, Jochen Hampe, Sabrina Schlesinger, Wolfgang Lieb

Skip metastasis in papillary thyroid carcinoma is difficult to predict in clinical practice

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Xilin Nie, Zhou Tan, Minghua Ge

Diabetes and risk of cancer incidence: results from a population-based cohort study in northern Italy

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Paola Ballotari, Massimo Vicentini, Valeria Manicardi, Marco Gallo, Sofia Chiatamone Ranieri, Marina Greci, Paolo Giorgi Rossi

Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia

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Maggie Kirkman, Kate Young, Susan Evans, Jeremy Millar, Jane Fisher, Danielle Mazza, Rasa Ruseckaite

PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival

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Heli Repo, Natalia Gurvits, Eliisa Löyttyniemi, Marjukka Nykänen, Minnamaija Lintunen, Henna Karra, Samu Kurki, Teijo Kuopio, Kati Talvinen, Mirva Söderström, Pauliina Kronqvist

Oral primary care: an analysis of its impact on the incidence and mortality rates of oral cancer

• Open Access
• Research article

Thiago Augusto Hernandes Rocha, Erika Bárbara Abreu Fonseca Thomaz, Núbia Cristina da Silva, Rejane Christine de Sousa Queiroz, Marta Rovery de Souza, Allan Claudius Queiroz Barbosa, Elaine Thumé, João Victor Muniz Rocha, Viviane Alvares, Dante Grapiuna de Almeida, João Ricardo Nickenig Vissoci, Catherine Ann Staton, Luiz Augusto Facchini

Identifying factors associated with the direction and significance of microRNA tumor-normal expression differences in colorectal cancer

• Open Access
• Research article

John R. Stevens, Jennifer S. Herrick, Roger K. Wolff, Martha L. Slattery

Non-invasively predicting differentiation of pancreatic cancer through comparative serum metabonomic profiling

• Open Access
• Research article

Shi Wen, Bohan Zhan, Jianghua Feng, Weize Hu, Xianchao Lin, Jianxi Bai, Heguang Huang

Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform

• Open Access
• Technical advance

Henriette L. Lanz, Anthony Saleh, Bart Kramer, Junmei Cairns, Chee Ping Ng, Jia Yu, Sebastiaan J. Trietsch, Thomas Hankemeier, Jos Joore, Paul Vulto, Richard Weinshilboum, Liewei Wang

Incorporating 18FDG-PET-defined pelvic active bone marrow in the automatic treatment planning process of anal cancer patients undergoing chemo-radiation

• Open Access
• Technical advance

Pierfrancesco Franco, Christian Fiandra, Francesca Arcadipane, Elisabetta Trino, Francesca Romana Giglioli, Riccardo Ragona, Umberto Ricardi

Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

• Open Access
• Research article

Katharina Gohr, Alexandra Hamacher, Laura H. Engelke, Matthias U. Kassack

A modified endoscopic submucosal dissection for a superficial hypopharyngeal cancer: a case report and technical discussion

• Open Access
• Case report

Lianjun Di, Kuang-I Fu, Rui Xie, Xinglong Wu, Youfeng Li, Huichao Wu, Biguang Tuo

Prospective study of 11C–methionine PET for distinguishing between recurrent brain metastases and radiation necrosis: limitations of diagnostic accuracy and long-term results of salvage treatment

• Open Access
• Research article

Shoji Yomo, Kazuhiro Oguchi

Transcatheter arterial chemoembolization plus sorafenib versus transcatheter arterial chemoembolization alone to treat advanced hepatocellular carcinoma: a meta-analysis

• Open Access
• Research article

Rong Cai, Rongfeng Song, Pengfei Pang, Yan Yan, Yifeng Liao, Cuiling Zhou, Shuncong Wang, Xiuling Zhou, Huaping Wang, Hongyu Zhang, Huanhuan Sun, Haiqing Ma

Oncology practitioners’ perspectives and practice patterns of post-treatment cancer survivorship care in the Asia-Pacific region: results from the STEP study

• Open Access
• Research article

Raymond Javan Chan, Patsy Yates, Qiuping Li, Hiroko Komatsu, Violeta Lopez, Myat Thandar, Selva Titus Chacko, Winnie Kwok Wei So, Kanaungnit Pongthavornkamol, Myungsun Yi, Pongpak Pittayapan, Jesson Butcon, David Wyld, Alex Molassiotis

Long intergenic non-protein-coding RNA 1567 (LINC01567) acts as a “sponge” against microRNA-93 in regulating the proliferation and tumorigenesis of human colon cancer stem cells

• Open Access
• Research article

Xiaofeng Yu, Lin Mi, Jie Dong, Jian Zou

Treatment of gastrointestinal stromal tumours in paediatric and young adult patients with sunitinib: a multicentre case series

• Open Access
• Research article

Piotr Rutkowski, Heather Magnan, Alexander J. Chou, Charlotte Benson

Constitutional mutation in CDKN2A is associated with long term survivorship in multiple myeloma: a case report

• Open Access
• Case report

Vallari Shah, Kevin D. Boyd, Richard S. Houlston, Martin F. Kaiser

Transcription factor E2F1 promotes EMT by regulating ZEB2 in small cell lung cancer

• Open Access
• Research article

Tingting Wang, Xufang Chen, Weiwei Qiao, Lijun Kong, Daqing Sun, Zunling Li

Synchronous occurrence of hereditary gastric adenocarcinoma, gastrointestinal stromal tumor, and esophageal small cell and squamous carcinoma in situ: an extremely rare case report

• Open Access
• Case report

Huijie Fan, Pei Lu, Li Xu, Yanru Qin, Jing Li

Carbon ion radiotherapy for 80 years or older patients with hepatocellular carcinoma

• Open Access
• Research article

Shintaro Shiba, Takanori Abe, Kei Shibuya, Hiroyuki Katoh, Yoshinori Koyama, Hirohumi Shimada, Satoru Kakizaki, Ken Shirabe, Hiroyuki Kuwano, Tatsuya Ohno, Takashi Nakano

Trastuzumab resumption after extremely severe cardiotoxicity in metastatic breast cancer patient: a case report

• Open Access
• Case report

Santino Minichillo, Ilaria Gallelli, Elena Barbieri, Marta Cubelli, Daniela Rubino, Sara Quercia, Massimo Dall’Olio, Claudio Rapezzi, Claudio Zamagni

microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer

• Open Access
• Research article

Hidekazu Takahashi, Masanobu Takahashi, Shinobu Ohnuma, Michiaki Unno, Yuki Yoshino, Kota Ouchi, Shin Takahashi, Yasuhide Yamada, Hideki Shimodaira, Chikashi Ishioka

Does hair dye use really increase the risk of prostate cancer?

• Open Access
• Correspondence

Bang-Ping Jiann

Prognostic and clinicopathological significance of circulating tumor cells detected by RT-PCR in non-metastatic colorectal cancer: a meta-analysis and systematic review

• Open Access
• Research article

Chaogang Yang, Kun Zou, Liang Zheng, Bin Xiong

Seropositivity to herpes simplex virus type 2, but not type 1 is associated with cervical cancer: NHANES (1999–2014)

• Open Access
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Sen Li, Xi Wen

Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer

• Open Access
• Research article

Melissa Quintero, Douglas Adamoski, Larissa Menezes dos Reis, Carolline Fernanda Rodrigues Ascenção, Krishina Ratna Sousa de Oliveira, Kaliandra de Almeida Gonçalves, Marília Meira Dias, Marcelo Falsarella Carazzolle, Sandra Martha Gomes Dias

MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours

• Open Access
• Research article

Malgorzata Bulkowska, Agata Rybicka, Kerem Mert Senses, Katarzyna Ulewicz, Katarzyna Witt, Joanna Szymanska, Bartlomiej Taciak, Robert Klopfleisch, Eva Hellmén, Izabella Dolka, Ali O. Gure, Joanna Mucha, Mariusz Mikow, Slawomir Gizinski, Magdalena Krol

A novel chemotherapeutic sensitivity-testing system based on collagen gel droplet embedded 3D–culture methods for hepatocellular carcinoma

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• Research article

Jun Hou, Zhixian Hong, Fan Feng, Yantao Chai, Yunkai Zhang, Qiyu Jiang, Yan Hu, Shunquan Wu, Yingsong Wu, Xunian Gao, Qiong Chen, Yong Wan, Jingfeng Bi, Zheng Zhang

Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients

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Edgars Endzeliņš, Andreas Berger, Vita Melne, Cristina Bajo-Santos, Kristīne Soboļevska, Artūrs Ābols, Marta Rodriguez, Daiga Šantare, Anastasija Rudņickiha, Vilnis Lietuvietis, Alicia Llorente, Aija Linē

Alterations in PGC1α expression levels are involved in colorectal cancer risk: a qualitative systematic review

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Jéssica Alonso-Molero, Carmen González-Donquiles, Tania Fernández-Villa, Fernanda de Souza-Teixeira, Laura Vilorio-Marqués, Antonio J. Molina, Vicente Martín

Pneumatosis cystoides intestinalis associated with sunitinib and a literature review

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• Case report

Yong Suk Lee, Jae Joon Han, Si-Young Kim, Chi Hoon Maeng

Comparison of different therapeutic strategies for complete hydatidiform mole in women at least 40 years old: a retrospective cohort study

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Peng Zhao, Qinqing Chen, Weiguo Lu

Barriers to HPV self-sampling and cytology among low-income indigenous women in rural areas of a middle-income setting: a qualitative study

• Open Access
• Research article

Betania Allen-Leigh, Patricia Uribe-Zúñiga, Leith León-Maldonado, Brandon J. Brown, Attila Lörincz, Jorge Salmeron, Eduardo Lazcano-Ponce

Successful pregnancy without disease progression of radioiodine refractory papillary thyroid carcinoma: a case report

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• Case report

Yuchen Jin, Min Liu, Lingxiao Cheng, Libo Chen

Ablation of epidermal RXRα in cooperation with activated CDK4 and oncogenic NRAS generates spontaneous and acute neonatal UVB induced malignant metastatic melanomas

• Open Access
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Sharmeen Chagani, Rong Wang, Evan L. Carpenter, Christiane V. Löhr, Gitali Ganguli-Indra, Arup K. Indra

Diagnostic and prognostic value of CEA, CA19–9, AFP and CA125 for early gastric cancer

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Fan Feng, Yangzi Tian, Guanghui Xu, Zhen Liu, Shushang Liu, Gaozan Zheng, Man Guo, Xiao Lian, Daiming Fan, Hongwei Zhang

Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing

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Soundararajan Krishnaswamy, Abdul Khader Mohammed, Gyanendra Tripathi, Majed S. Alokail, Nasser M. Al-Daghri

Prevalence and associated factors of medication non-adherence in hematological-oncological patients in their home situation

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Linda Bouwman, Corien M. Eeltink, Otto Visser, Jeroen J. W. M. Janssen, Jolanda M. Maaskant

Optimal interval of endoscopic screening based on stage distributions of detected gastric cancers

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Chisato Hamashima, Rintaro Narisawa, Kazuei Ogoshi, Toshiyuki Kato, Kazutaka Fujita

Perceived stigmatization and its impact on quality of life - results from a large register-based study including breast, colon, prostate and lung cancer patients

• Open Access
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J. Ernst, A. Mehnert, A. Dietz, B. Hornemann, P. Esser

RAM score is an effective predictor for early mortality and recurrence after hepatectomy for hepatocellular carcinoma

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Heng-Yuan Hsu, Ming-Chin Yu, Chao-Wei Lee, Hsin-I Tsai, Chang-Mu Sung, Chun-Wei Chen, Shu-Wei Huang, Cheng-Yu Lin, Wen-Juei Jeng, Wei-Chen Lee, Miin-Fu Chen

TP53 Arg72 as a favorable prognostic factor for Chinese diffuse large B-cell lymphoma patients treated with CHOP

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Yalu Liu, Xiaogan Wang, Ning Ding, Lan Mi, Lingyan Ping, Xuan Jin, Jiao Li, Yan Xie, Zhitao Ying, Weiping Liu, Chen Zhang, Lijuan Deng, Yuqin Song, Jun Zhu

The preoperative neutrophil to lymphocyte ratio is a superior indicator of prognosis compared with other inflammatory biomarkers in resectable colorectal cancer

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Yongxi Song, Yuchong Yang, Peng Gao, Xiaowan Chen, Dehao Yu, Yingying Xu, Junhua Zhao, Zhenning Wang

miR-17-5p suppresses cell proliferation and invasion by targeting ETV1 in triple-negative breast cancer

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Jie Li, Yuanhui Lai, Jieyi Ma, Yue Liu, Jiong Bi, Longjuan Zhang, Lianzhou Chen, Chen Yao, Weiming Lv, Guangqi Chang, Shenming Wang, Mao Ouyang, Wenjian Wang

Contrast-enhanced ultrasound of small cell carcinoma in urinary bladder: a case report and review of literature

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• Case report

Meixiang Zhang, Chengcheng Niu, Ming Zhang, Qinghai Peng, Minzhi Ouyang

Venous thromboembolism and mortality in breast cancer: cohort study with systematic review and meta-analysis

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Umair T. Khan, Alex J. Walker, Sadaf Baig, Tim R. Card, Cliona C. Kirwan, Matthew J. Grainge

Thoracoscopic and hand assisted laparoscopic esophagectomy with radical lymph node dissection for esophageal squamous cell carcinoma in the left lateral decubitus position: a single center retrospective analysis of 654 patients

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Masahiko Murakami, Koji Otsuka, Satoru Goto, Tomotake Ariyoshi, Takeshi Yamashita, Takeshi Aoki

YRNA expression predicts survival in bladder cancer patients

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Yuri Tolkach, Anna Franziska Stahl, Eva-Maria Niehoff, Chenming Zhao, Glen Kristiansen, Stefan Cajetan Müller, Jörg Ellinger

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1

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Priscila Daniele Ramos Cirilo, Luciana Nogueira de Sousa Andrade, Bruna Renata Silva Corrêa, Mei Qiao, Tatiane Katsue Furuya, Roger Chammas, Luiz Otavio Ferraz Penalva

Genomic determinants of long-term cardiometabolic complications in childhood acute lymphoblastic leukemia survivors

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Jade England, Simon Drouin, Patrick Beaulieu, Pascal St-Onge, Maja Krajinovic, Caroline Laverdière, Emile Levy, Valérie Marcil, Daniel Sinnett

Feasibility of structured endurance training and Mediterranean diet in BRCA1 and BRCA2 mutation carriers – an interventional randomized controlled multicenter trial (LIBRE-1)

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Marion Kiechle, Ricarda Dukatz, Maryam Yahiaoui-Doktor, Anika Berling, Maryam Basrai, Vera Staiger, Uwe Niederberger, Nicole Marter, Jacqueline Lammert, Sabine Grill, Katharina Pfeifer, Kerstin Rhiem, Rita K. Schmutzler, Matthias Laudes, Michael Siniatchkin, Martin Halle, Stephan C. Bischoff, Christoph Engel

Safety and efficacy of abiraterone acetate in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: an Italian multicenter “real life” study

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Luca Cindolo, Clara Natoli, Cosimo De Nunzio, Michele De Tursi, Maurizio Valeriani, Silvana Giacinti, Salvatore Micali, Mino Rizzo, Giampaolo Bianchi, Eugenio Martorana, Marcello Scarcia, Giuseppe Mario Ludovico, Pierluigi Bove, Anastasia Laudisi, Oscar Selvaggio, Giuseppe Carrieri, Maida Bada, Pietro Castellan, Stefano Boccasile, Pasquale Ditonno, Paolo Chiodini, Paolo Verze, Vincenzo Mirone, Luigi Schips

Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer

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Paulo Roberto Stevanato Filho, Samuel Aguiar Júnior, Maria Dirlei Begnami, Hellen Kuasne, Ranyell Matheus Spencer, Wilson Toshihiko Nakagawa, Tiago Santoro Bezerra, Bruna Catin Kupper, Renata Maymi Takahashi, Mateus Barros Filho, Silvia Regina Rogatto, Ademar Lopes

Association between gene expression profile of the primary tumor and chemotherapy response of metastatic breast cancer

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Cemile Dilara Savci-Heijink, Hans Halfwerk, Jan Koster, Marc Joan Van de Vijver

CAISMOV24, a new human low-grade serous ovarian carcinoma cell line

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Rodrigo Fernandes da Silva, Daniela Maira Cardozo, Gisele Olinto Libanio Rodrigues, Caroline Natânia de Souza-Araújo, Natacha Azussa Migita, Liliana Aparecida Lucci de Angelo Andrade, Sophie Derchain, José Andrés Yunes, Fernando Guimarães

Diet and endometrial cancer: a focus on the role of fruit and vegetable intake, Mediterranean diet and dietary inflammatory index in the endometrial cancer risk

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Fulvio Ricceri, Maria Teresa Giraudo, Francesca Fasanelli, Dario Milanese, Veronica Sciannameo, Laura Fiorini, Carlotta Sacerdote

The association of polymorphic markers Arg399Gln of XRCC1 gene, Arg72Pro of TP53 gene and T309G of MDM2 gene with breast cancer in Kyrgyz females

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Jainagul Isakova, Elnura Talaibekova, Nazira Aldasheva, Denis Vinnikov, Almaz Aldashev

Gene expression signatures of neuroendocrine prostate cancer and primary small cell prostatic carcinoma

• Open Access
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Harrison K. Tsai, Jonathan Lehrer, Mohammed Alshalalfa, Nicholas Erho, Elai Davicioni, Tamara L. Lotan

Meta-analysis comparing laparoscopic versus open resection for gastric gastrointestinal stromal tumors larger than 5 cm

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• Research article

Xiao Lian, Fan Feng, Man Guo, Lei Cai, Zhen Liu, Shushang Liu, Shuao Xiao, Gaozan Zheng, Guanghui Xu, Hongwei Zhang

Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma

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Cliff I. Oduor, Yasin Kaymaz, Kiprotich Chelimo, Juliana A. Otieno, John Michael Ong’echa, Ann M. Moormann, Jeffrey A. Bailey

Perioperative blood transfusion does not affect recurrence-free and overall survivals after curative resection for intrahepatic cholangiocarcinoma: a propensity score matching analysis

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Pei-Yun Zhou, Zheng Tang, Wei-Ren Liu, Meng-Xin Tian, Lei Jin, Xi-Fei Jiang, Han Wang, Chen-Yang Tao, Zhen-Bin Ding, Yuan-Fei Peng, Shuang-Jian Qiu, Zhi Dai, Jian Zhou, Jia Fan, Ying-Hong Shi

Effects of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs on the incidence of recurrent colorectal adenomas: a systematic review with meta-analysis and trial sequential analysis of randomized clinical trials

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Sajesh K. Veettil, Kean Ghee Lim, Siew Mooi Ching, Surasak Saokaew, Pochamana Phisalprapa, Nathorn Chaiyakunapruk

Preoperative T staging using CT colonography with multiplanar reconstruction for very low rectal cancer

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Dai Shida, Gen Iinuma, Akira Komono, Hiroki Ochiai, Shunsuke Tsukamoto, Mototaka Miyake, Yukihide Kanemitsu

Analysis of factors influencing molecular testing at diagnostic of colorectal cancer

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Quentin Thiebault, Gautier Defossez, Lucie Karayan-Tapon, Pierre Ingrand, Christine Silvain, David Tougeron

Bidirectional alteration of Cav-1 expression is associated with mitogenic conversion of its function in gastric tumor progression

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• Research article

Byung-Kyu Ryu, Min-Goo Lee, Nam-Hoon Kim, Kil Yeon Lee, Shin-Ju Oh, Jung-Rock Moon, Hyo Jong Kim, Sung-Gil Chi

DETECT I & DETECT II: a study protocol for a prospective multicentre observational study to validate the UroMark assay for the detection of bladder cancer from urinary cells

• Open Access
• Study protocol

Wei Shen Tan, Andrew Feber, Liqin Dong, Rachael Sarpong, Sheida Rezaee, Simon Rodney, Pramit Khetrapal, Patricia de Winter, Frelyn Ocampo, Rumana Jalil, Norman R. Williams, Chris Brew-Graves, John D. Kelly

In response to Fogarty et al. and why adjuvant whole brain radiotherapy is not recommended routinely

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• Correspondence

Mark B. Pinkham, Arjun Sahgal, Andrew P. Pullar, Matthew C. Foote

Risk factors associated with the progression and metastases of hindgut neuroendocrine tumors: a retrospective study

• Open Access
• Research article

Yoichiro Okubo, Rika Kasajima, Masaki Suzuki, Yohei Miyagi, Osamu Motohashi, Manabu Shiozawa, Emi Yoshioka, Kota Washimi, Kae Kawachi, Yoichi Kameda, Tomoyuki Yokose

Renal failure during chemotherapy: renal biopsy for assessing subacute nephrotoxicity of pemetrexed

• Open Access
• Case report

Maureen Assayag, Philippe Rouvier, Marion Gauthier, Ghania Costel, Philippe Cluzel, Lucile Mercadal, Gilbert Deray, Corinne Isnard Bagnis

Cytoreductive surgery and Hyperthermic intra-operative peritoneal chemotherapy with Cisplatin for gastric peritoneal Carcinomatosis Monocentric phase-2 nonrandomized prospective clinical trial

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• Research article

Baki Topal, Karel Demey, Halit Topal, Joris Jaekers, Eric Van Cutsem, Vincent Vandecaveye, Xavier Sagaert, Hans Prenen

Process quality of decision-making in multidisciplinary cancer team meetings: a structured observational study

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• Research article

Pola Hahlweg, Sarah Didi, Levente Kriston, Martin Härter, Yvonne Nestoriuc, Isabelle Scholl

Cost-effectiveness analysis of the introduction of S-1 therapy for first-line metastatic breast cancer treatment in Japan: results from the randomized phase III SELECT BC trial

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Takeru Shiroiwa, Takashi Fukuda, Kojiro Shimozuma, Mitsuko Mouri, Yasuhiro Hagiwara, Takuya Kawahara, Shozo Ohsumi, Yasuo Hozumi, Yoshiaki Sagara, Yasuo Ohashi, Hirofumi Mukai

Survival time following resection of intracranial metastases from NSCLC-development and validation of a novel nomogram

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• Research article

Xiaoyu Ji, Yingjie Zhuang, Xiangye Yin, Qiong Zhan, Xinli Zhou, Xiaohua Liang

Sorafenib treatment for papillary thyroid carcinoma with diffuse lung metastases in a child with autism spectrum disorder: a case report

• Open Access
• Case report

Yousuke Higuchi, Takayuki Motoki, Hisashi Ishida, Kiichiro Kanamitsu, Kana Washio, Takanori Oyama, Takuo Noda, Yasuko Tsurumaru, Ayumi Okada, Hirokazu Tsukahara, Akira Shimada

A qualitative study on Singaporean women’s views towards breast cancer screening and Single Nucleotide Polymorphisms (SNPs) gene testing to guide personalised screening strategies

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Xin Yi Wong, Kok Joon Chong, Janine A. van Til, Hwee Lin Wee

Does anthracycline-based chemotherapy in pregnant women with cancer offer safe cardiac and neurodevelopmental outcomes for the developing fetus?

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• Debate

Marialuisa Framarino-dei-Malatesta, Paolo Sammartino, Angela Napoli

Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report

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• Case report

Yukinori Ozaki, Junichi Shindoh, Yuji Miura, Hiromichi Nakajima, Ryosuke Oki, Miyuki Uchiyama, Jun Masuda, Keiichi Kinowaki, Chihiro Kondoh, Yuko Tanabe, Tsuyoshi Tanaka, Shusuke Haruta, Masaki Ueno, Shigehisa Kitano, Takeshi Fujii, Harushi Udagawa, Toshimi Takano

In vitro characterization of CD133lo cancer stem cells in Retinoblastoma Y79 cell line

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• Research article

Rohini M. Nair, Murali MS. Balla, Imran Khan, Ravi Kiran Reddy Kalathur, Paturu Kondaiah, Geeta K. Vemuganti

Treatment recommendations within the leeway of clinical guidelines: A qualitative interview study on oncologists’ clinical deliberation

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• Research article

I. Otte, S. Salloch, A. Reinacher-Schick, J. Vollmann

Stereotactic body radiotherapy (SBRT) for locally advanced intrahepatic and extrahepatic cholangiocarcinoma

• Open Access
• Research article

Eleni Gkika, Lukas Hallauer, Simon Kirste, Sonja Adebahr, Nico Bartl, Hannes Philipp Neeff, Ralph Fritsch, Volker Brass, Ursula Nestle, Anca Ligia Grosu, Thomas Baptist Brunner

Polymorphisms in ADH1B and ALDH2 genes associated with the increased risk of gastric cancer in West Bengal, India

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• Research article

Sudakshina Ghosh, Biswabandhu Bankura, Soumee Ghosh, Makhan Lal Saha, Arup Kumar Pattanayak, Souvik Ghatak, Manalee Guha, Senthil Kumar Nachimuthu, Chinmoy Kumar Panda, Suvendu Maji, Subrata Chakraborty, Biswanath Maity, Madhusudan Das

The risk and survival outcome of subsequent primary colorectal cancer after the first primary colorectal cancer: cases from 1973 to 2012

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• Research article

Jiao Yang, Xianglin L. Du, Shuting Li, Yinying Wu, Meng Lv, Danfeng Dong, Lingxiao Zhang, Zheling Chen, Biyuan Wang, Fan Wang, Yanwei Shen, Enxiao Li, Min Yi, Jin Yang

King’s Health Partners’ Prostate Cancer Biobank (KHP PCaBB)

• Open Access
• Database

S. R. Saifuddin, W. Devlies, A. Santaolalla, F. Cahill, G. George, D. Enting, S. Rudman, P. Cathcart, B. Challacombe, P. Dasgupta, C. Galustian, A. Chandra, S. Chowdhury, C. Gillett, M. Van Hemelrijck

The ANDROMEDA prospective cohort study: predictive value of combined criteria to tailor breast cancer screening and new opportunities from circulating markers: study protocol

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• Study protocol

Livia Giordano, Federica Gallo, Elisabetta Petracci, Giovanna Chiorino, Nereo Segnan, Caterina Anatrone, Franca Artuso, Marcella Beraudi, Denise Casella, Matilde Ceresa, Francesca Di Stefano, Marta Dotti, Simona Feira, Alfonso Frigerio, Francesca Garena, Pamela Giubilato, Maria Piera Mano, Vincenzo Marra, Andrea Menardi, Andrea Ortale, Stefania Pelosin, Andrea Pezzana, Sabina Pitarella, Antonio Ponti, Francesca Saba, Viviana Vergini, Piera Vicari, Salad Heddine Ayoubi, Alessandra Debianchi, Elisabetta Favettini, Ilaria Gregnanin, Lorella Iacazio, Maurizia Mello-Grand, Paola Ostano, Pietro Presti

Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients

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• Research article

Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Aiko Sueta, Mai Tomiguchi, Keiichi Murakami, Yoko Omoto, Hirotaka Iwase

Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer

• Open Access
• Research article

Mingshan Liu, Yang Liu, Jiabo Di, Zhe Su, Hong Yang, Beihai Jiang, Zaozao Wang, Meng Zhuang, Fan Bai, Xiangqian Su

Patient- and treatment-related risk factors associated with neck muscle spasm in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy

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• Research article

Lu-Lu Zhang, Guan-Qun Zhou, Zhen-Yu Qi, Xiao-Jun He, Jia-Xiang Li, Ling-Long Tang, Yan-Ping Mao, Ai-Hua Lin, Jun Ma, Ying Sun

Intermediate PSA half-life after neoadjuvant hormone therapy predicts reduced risk of castration-resistant prostate cancer development after radical prostatectomy

• Open Access
• Research article

Yong Jin Kang, Won Sik Jang, Jong Kyou Kwon, Cheol Yong Yoon, Joo Yong Lee, Won Sik Ham, Young Deuk Choi

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

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• Research article

Doreen Huebner, Christiane Rieger, Ralf Bergmann, Martin Ullrich, Sebastian Meister, Marieta Toma, Ralf Wiedemuth, Achim Temme, Vladimir Novotny, Manfred P. Wirth, Michael Bachmann, Jens Pietzsch, Susanne Fuessel

Estimating the value of point-of-care HPV testing in three low- and middle-income countries: a modeling study

• Open Access
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Nicole G. Campos, Vivien Tsu, Jose Jeronimo, Mercy Mvundura, Jane J. Kim

Prevalence and types of high-risk human papillomaviruses in head and neck cancers from Bangladesh

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• Research article

Mushfiq H. Shaikh, Aminul I. Khan, Anwar Sadat, Ahmed H. Chowdhury, Shahed A. Jinnah, Vinod Gopalan, Alfred K. Lam, Daniel T. W. Clarke, Nigel A. J. McMillan, Newell W. Johnson

Smoking and alcohol cessation intervention in relation to radical cystectomy: a qualitative study of cancer patients’ experiences

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• Research article

Susanne Vahr Lauridsen, Thordis Thomsen, Gudrun Kaldan, Line Noes Lydom, Hanne Tønnesen

The enablers, barriers and preferences of accessing radiation therapy facilities in the rural developed world – a systematic review

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Sandra C. Thompson, Shelley Cheetham, Siddhartha Baxi

Sertad1 antagonizes iASPP function by hindering its entrance into nuclei to interact with P53 in leukemic cells

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• Research article

Shaowei Qiu, Shuang Liu, Tengteng Yu, Jing Yu, Min Wang, Qing Rao, Haiyan Xing, Kejing Tang, Yinchang Mi, Jianxiang Wang

Subjective cognitive impairment and brain structural networks in Chinese gynaecological cancer survivors compared with age-matched controls: a cross-sectional study

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• Research article

Yingchun Zeng, Andy S. K. Cheng, Ting Song, Xiujie Sheng, Yang Zhang, Xiangyu Liu, Chetwyn C. H. Chan

Serum albumin level as a potential marker for deciding chemotherapy or best supportive care in elderly, advanced non-small cell lung cancer patients with poor performance status

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• Research article

Satoshi Ikeda, Hiroshige Yoshioka, Satoshi Ikeo, Mitsunori Morita, Naoyuki Sone, Takashi Niwa, Akihiro Nishiyama, Toshihide Yokoyama, Akimasa Sekine, Takashi Ogura, Tadashi Ishida

Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review

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J. Han van Krieken, George Kafatos, James Bennett, Laurent Mineur, Jiří Tomášek, Etienne Rouleau, Pavel Fabian, Giovanna De Maglio, Pilar García-Alfonso, Giuseppe Aprile, Parijan Parkar, Gerald Downey, Gaston Demonty, Jörg Trojan

Robust expression of tumor suppressor miRNA’s let-7 and miR-195 detected in plasma of Saudi female breast cancer patients

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Amal Qattan, Haya Intabli, Wafa Alkhayal, Chafica Eltabache, Taher Tweigieri, Suad Bin Amer

Unfavorable impact of cancer cachexia on activity of daily living and need for inpatient care in elderly patients with advanced non-small-cell lung cancer in Japan: a prospective longitudinal observational study

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Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori, Kazuhisa Nakashima, Masahiro Endo, Katsuhiro Omae, Keita Mori, Nobuyuki Yamamoto, Akira Tanuma, Toshiaki Takahashi

Thymoma with acute gastric volvulus: a case report

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• Case report

Ailing Liu, Xin Gao, Lin Zhao

Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling

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Govindasamy-Muralidharan Karthik, Mattias Rantalainen, Gustav Stålhammar, John Lövrot, Ikram Ullah, Amjad Alkodsi, Ran Ma, Lena Wedlund, Johan Lindberg, Jan Frisell, Jonas Bergh, Johan Hartman

Isolation and characterization of a new naturally immortalized human breast carcinoma cell line, KAIMRC1

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Rizwan Ali, Nosaibah Samman, Hajar Al Zahrani, Atef Nehdi, Sabhi Rahman, Abdul Latif Khan, Mohamed Al Balwi, Lolwah Abdullah Alriyees, Manal Alzaid, Ahmed Al Askar, Mohamed Boudjelal

Immunohistochemistry defined subtypes of breast cancer in 678 Sudanese and Eritrean women; hospitals based case series

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Asmerom Tesfamariam Sengal, Nada Suliman Haj-Mukhtar, Ahmed Mohammed Elhaj, Shahinaz Bedri, Eva Johanna Kantelhardt, Ahmed A. Mohamedani

MicroRNA profile in HBV-induced infection and hepatocellular carcinoma

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Guanyu Wang, Fulu Dong, Zhiyao Xu, Sherven Sharma, Xiaotong Hu, Dafang Chen, Lumin Zhang, Jinping Zhang, Qinghua Dong

Assessing the outcomes of HIV-infected persons receiving treatment for Kaposi sarcoma in Conakry-Guinea

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Cavin E. Bekolo, Mohamed M. Soumah, Ousseni W. Tiemtore, Abdourahimi Diallo, Joseph-Desire Yuma, Letizia Di Stefano, Carol Metcalf, Mohamed Cisse

Partnering around cancer clinical trials (PACCT): study protocol for a randomized trial of a patient and physician communication intervention to increase minority accrual to prostate cancer clinical trials

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• Study protocol

Susan Eggly, Lauren M. Hamel, Elisabeth Heath, Mark A. Manning, Terrance L. Albrecht, Ellen Barton, Mark Wojda, Tanina Foster, Michael Carducci, Dina Lansey, Ting Wang, Rehab Abdallah, Narineh Abrahamian, Seongho Kim, Nicole Senft, Louis A. Penner

Prevalence of incidental breast cancer and precursor lesions in autopsy studies: a systematic review and meta-analysis

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Elizabeth T. Thomas, Chris Del Mar, Paul Glasziou, Gordon Wright, Alexandra Barratt, Katy J. L. Bell

Characteristics and outcome in patients with non-specific symptoms and signs of cancer referred to a fast track cancer patient pathway; a retrospective cohort study

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Sara Falk Jørgensen, Pernille Ravn, Søren Thorsen, Signe Westring Worm

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

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Monika Bauden, Theresa Kristl, Agata Sasor, Bodil Andersson, György Marko-Varga, Roland Andersson, Daniel Ansari

EpCAM expression in squamous cell carcinoma of the uterine cervix detected by monoclonal antibody to the membrane-proximal part of EpCAM

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Warangkana Chantima, Charin Thepthai, Pornsuk Cheunsuchon, Tararaj Dharakul

Prediction of postoperative inflammatory complications after esophageal cancer surgery based on early changes in the C-reactive protein level in patients who received perioperative steroid therapy and enhanced recovery after surgery care: a retrospective analysis

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Kazuki Kano, Toru Aoyama, Tetsushi Nakajima, Yukio Maezawa, Tsutomu Hayashi, Takanobu Yamada, Tsutomu Sato, Takashi Oshima, Yasushi Rino, Munetaka Masuda, Haruhiko Cho, Takaki Yoshikawa, Takashi Ogata

Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway

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Panpan Zhou, Chunling Wang, Zebin Hu, Wenruo Chen, Wentao Qi, Aike Li

Influences on anticipated time to ovarian cancer symptom presentation in women at increased risk compared to population risk of ovarian cancer

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Stephanie Smits, Jacky Boivin, Usha Menon, Kate Brain

Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma

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Wenting Huang, Xuemin Xue, Ling Shan, Tian Qiu, Lei Guo, Jianming Ying, Ning Lu

Google as a cancer control tool in Queensland

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Xiaodong Huang, Peter Baade, Danny R. Youlden, Philippa H. Youl, Wenbiao Hu, Michael G. Kimlin

Routine blood tests and probability of cancer in patients referred with non-specific serious symptoms: a cohort study

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Esben Næser, Henrik Møller, Ulrich Fredberg, Jan Frystyk, Peter Vedsted

High-precision radiotherapy of motor deficits due to metastatic spinal cord compression (PRE-MODE): a multicenter phase 2 study

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• Study protocol

Dirk Rades, Jon Cacicedo, Antonio J. Conde-Moreno, Claudia Doemer, Jürgen Dunst, Darejan Lomidze, Barbara Segedin, Denise Olbrich, Niels Henrik Holländer

Efficacy and safety of eribulin in patients with locally advanced or metastatic breast cancer not meeting trial eligibility criteria: a retrospective study

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Sakura Iizumi, Tatsunori Shimoi, Natsuko Tsushita, Seiko Bun, Akihiko Shimomura, Emi Noguchi, Makoto Kodaira, Mayu Yunokawa, Kan Yonemori, Chikako Shimizu, Yasuhiro Fujiwara, Kenji Tamura

Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer

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Aleksandra M. Ochnik, Robert C. Baxter

Comparison of the association of mammographic density and clinical factors with ductal carcinoma in situ versus invasive ductal breast cancer in Korean women

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Hyeonyoung Ko, Jinyoung Shin, Jeong Eon Lee, Seok Jin Nam, Tuong Linh Nguyen, John Llewelyn Hopper, Yun-Mi Song

A partially supervised physical activity program for adult and adolescent survivors of childhood cancer (SURfit): study design of a randomized controlled trial [NCT02730767]

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Corina S. Rueegg, Susi Kriemler, Simeon J. Zuercher, Christina Schindera, Andrea Renner, Helge Hebestreit, Christian Meier, Prisca Eser, Nicolas X. von der Weid

Relevance of matrix metalloproteases in non-small cell lung cancer diagnosis

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Sonia Blanco-Prieto, Leticia Barcia-Castro, María Páez de la Cadena, Francisco Javier Rodríguez-Berrocal, Lorena Vázquez-Iglesias, María Isabel Botana-Rial, Alberto Fernández-Villar, Loretta De Chiara

Incidence of breast cancer in Chinese women exposed to the 1959–1961 great Chinese famine

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Dandan He, Yuan Fang, Marc J. Gunter, Dongli Xu, Yanping Zhao, Jie Zhou, Hong Fang, Wang Hong Xu

Concordance of FDG PET/CT metabolic tumour volume versus DW-MRI functional tumour volume with T2-weighted anatomical tumour volume in cervical cancer

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Alta Y. T. Lai, Jose A. U. Perucho, Xiaopei Xu, Edward S. Hui, Elaine Y. P. Lee

Study protocol for a cluster-randomized trial to compare human papillomavirus based cervical cancer screening in community-health campaigns versus health facilities in western Kenya

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• Study protocol

Megan J. Huchko, James G. Kahn, Jennifer S. Smith, Robert A. Hiatt, Craig R. Cohen, Elizabeth Bukusi

Decreased expression of the β2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

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Aitor Benedicto, Joana Marquez, Alba Herrero, Elvira Olaso, Elzbieta Kolaczkowska, Beatriz Arteta

Overexpression of Cullin7 is associated with hepatocellular carcinoma progression and pathogenesis

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Jun An, Zhigang Zhang, Zhiyong Liu, Ruizhi Wang, Dayang Hui, Yi Jin

Radiomics based analysis to predict local control and survival in hepatocellular carcinoma patients treated with volumetric modulated arc therapy

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Luca Cozzi, Nicola Dinapoli, Antonella Fogliata, Wei-Chung Hsu, Giacomo Reggiori, Francesca Lobefalo, Margarita Kirienko, Martina Sollini, Davide Franceschini, Tiziana Comito, Ciro Franzese, Marta Scorsetti, Po-Ming Wang

Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages

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Daifeng Wang, John D. Haley, Patricia Thompson

Leukocytoclastic vasculitis complicating cisplatin + radiation treatment for laryngeal cancer: a case report

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• Case report

Júlia Coelho França Quintanilha, Marília Berlofa Visacri, Laís Sampaio Amaral, Carmen Silvia Passos Lima, Maria Letícia Cintra, Patricia Moriel

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

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Thao N. D. Pham, Bethany E. Perez White, Huiping Zhao, Fariborz Mortazavi, Debra A. Tonetti

Low level laser therapy (Photobiomodulation therapy) for breast cancer-related lymphedema: a systematic review

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G. David Baxter, Lizhou Liu, Simone Petrich, Angela Spontelli Gisselman, Cathy Chapple, Juanita J. Anders, Steve Tumilty

CCL5-CCR5 interactions modulate metabolic events during tumor onset to promote tumorigenesis

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Darrin Gao, Lisa H. Cazares, Eleanor N. Fish

Cross sectional study of serum selenium concentration and esophageal squamous dysplasia in western Kenya

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Natalie R. Pritchett, Stephen L. Burgert, Gwen A. Murphy, John D. Brockman, Russell E. White, Justus Lando, Robert Chepkwony, Mark D. Topazian, Christian C. Abnet, Sanford M. Dawsey, Michael M. Mwachiro

A systematic review of test accuracy studies evaluating molecular micro-satellite instability testing for the detection of individuals with lynch syndrome

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Helen Coelho, Tracey Jones-Hughes, Tristan Snowsill, Simon Briscoe, Nicola Huxley, Ian M. Frayling, Chris Hyde

Study protocol of HGCSG1404 SNOW study: a phase I/II trial of combined chemotherapy of S-1, nab-paclitaxel and oxaliplatin administered biweekly to patients with advanced gastric cancer

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• Study protocol

Yasuyuki Kawamoto, Yoshito Komatsu, Satoshi Yuki, Kentaro Sawada, Tetsuhito Muranaka, Kazuaki Harada, Hiroshi Nakatsumi, Hiraku Fukushima, Atsushi Ishiguro, Masayoshi Dazai, Kazuteru Hatanaka, Michio Nakamura, Ichiro Iwanaga, Minoru Uebayashi, Susumu Sogabe, Yoshimitsu Kobayashi, Takuto Miyagishima, Kota Ono, Naoya Sakamoto, Yuh Sakata

Effect of siRNA-silencing of SALL2 gene on growth, migration and invasion of human ovarian carcinoma A2780 cells

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Fang Miao, Xueshan Zhang, Yanning Cao, Yue Wang, Xiaoshu Zhang

The prognosis of invasive micropapillary carcinoma compared with invasive ductal carcinoma in the breast: a meta-analysis

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Yun Wu, Ning Zhang, Qifeng Yang

Prediction of 5–year overall survival in cervical cancer patients treated with radical hysterectomy using computational intelligence methods

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Bogdan Obrzut, Maciej Kusy, Andrzej Semczuk, Marzanna Obrzut, Jacek Kluska

Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients

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Guo-dong Cao, Ke Chen, Bo Chen, Mao-ming Xiong

High blood glucose levels are associated with higher risk of colon cancer in men: a cohort study

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Alexandra Vulcan, Jonas Manjer, Bodil Ohlsson

Prevalence and characteristics of hereditary non-polyposis colorectal cancer (HNPCC) syndrome in immigrant Asian colorectal cancer patients

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Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang, Yiqing Xu

A network-based predictive gene-expression signature for adjuvant chemotherapy benefit in stage II colorectal cancer

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Bangrong Cao, Liping Luo, Lin Feng, Shiqi Ma, Tingqing Chen, Yuan Ren, Xiao Zha, Shujun Cheng, Kaitai Zhang, Changmin Chen

Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

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Simone Keller, Julia Kneissl, Verena Grabher-Meier, Stefan Heindl, Jan Hasenauer, Dieter Maier, Julian Mattes, Peter Winter, Birgit Luber

p53R2 as a novel prognostic biomarker in nasopharyngeal carcinoma

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Jiewei Chen, Shuman Li, Yongbo Xiao, Xuan Zou, Xinke Zhang, Mingshu Zhu, Muyan Cai, Dan Xie

Development of mobile technologies for the prevention of cervical cancer in Santiago, Chile study protocol: a randomized controlled trial

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• Study protocol

McKenzie C. Momany, Javiera Martinez-Gutierrez, Mauricio Soto, Daniel Capurro, Francis Ciampi, Beti Thompson, Klaus Puschel

Family history of prostate and colorectal cancer and risk of colorectal cancer in the Women’s health initiative

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Jennifer L. Beebe-Dimmer, Cecilia Yee, Electra Paskett, Ann G. Schwartz, Dorothy Lane, Nynikka R. A. Palmer, Cathryn H. Bock, Rami Nassir, Michael S. Simon

First-decade patient with colorectal cancer carrying both germline and somatic mutations in APC gene

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• Case report

Yung-Sung Yeh, Yu-Tang Chang, Cheng-Jen Ma, Ching-Wen Huang, Hsiang-Lin Tsai, Yi-Ting Chen, Jaw-Yuan Wang

Shifting cancer care towards Multidisciplinarity: the cancer center certification program of the German cancer society

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• Debate

Christoph Kowalski, Ullrich Graeven, Christof von Kalle, Hauke Lang, Matthias W. Beckmann, Jens-Uwe Blohmer, Martin Burchardt, Michael Ehrenfeld, Jan Fichtner, Stephan Grabbe, Hans Hoffmann, Heinrich Iro, Stefan Post, Anton Scharl, Uwe Schlegel, Thomas Seufferlein, Walter Stummer, Dieter Ukena, Julia Ferencz, Simone Wesselmann

Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells

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Juan Du, Hui-rong Shi, Fang Ren, Jing-lu Wang, Qing-hua Wu, Xia Li, Rui-tao Zhang

Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens

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John F. Seymour, Hartmut Döhner, Aleksandra Butrym, Agnieszka Wierzbowska, Dominik Selleslag, Jun Ho Jang, Rajat Kumar, James Cavenagh, Andre C. Schuh, Anna Candoni, Christian Récher, Irwindeep Sandhu, Teresa Bernal del Castillo, Haifa Kathrin Al-Ali, Jose Falantes, Richard M. Stone, Mark D. Minden, Jerry Weaver, Steve Songer, C. L. Beach, Hervé Dombret

Pancreatic schwannoma: a case report and an updated 40-year review of the literature yielding 68 cases

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• Case report

Yuntong Ma, Bingqi Shen, Yingmei Jia, Yanji Luo, Yisu Tian, Zhi Dong, Wei Chen, Zi-Ping Li, Shi-Ting Feng

Prognostic significance of RBP2-H1 variant of JARID1B in melanoma

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Łukasz Kuźbicki, Dariusz Lange, Agata Stanek-Widera, Barbara W. Chwirot

Overexpression of p53R2 is associated with poor prognosis in lung sarcomatoid carcinoma

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Jiewei Chen, Yongbo Xiao, Xiaoyan Cai, Jun Liu, Keming Chen, Xinke Zhang

Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites

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Tomi Akinyemiju, Justin Xavier Moore, Suzanne Judd, Susan Lakoski, Michael Goodman, Monika M. Safford, Maria Pisu

High mobility group box 1 promotes sorafenib resistance in HepG2 cells and in vivo

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Yinzong Xiao, Lunquan Sun, Yongming Fu, Yan Huang, Rongrong Zhou, Xingwang Hu, Pengcheng Zhou, Jun Quan, Ning Li, Xue-Gong Fan

Transcriptome analysis of genes associated with breast cancer cell motility in response to Artemisinin treatment

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Kanchan Kumari, Sunita Keshari, Debomita Sengupta, Surendra C. Sabat, Sandip K. Mishra

Mammographic density and risk of breast cancer by tumor characteristics: a case-control study

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Kavitha Krishnan, Laura Baglietto, Jennifer Stone, Catriona McLean, Melissa C. Southey, Dallas R. English, Graham G. Giles, John L. Hopper

Perceptions of colorectal cancer screening and recommendation behaviors among physicians in Korea

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Hye Young Shin, Mina Suh, Boyoung Park, Jae Kwan Jun, Kui Son Choi

Comprehensive analysis of differentially expressed genes associated with PLK1 in bladder cancer

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Zhe Zhang, Guojun Zhang, Zhipeng Gao, Shiguang Li, Zeliang Li, Jianbin Bi, Xiankui Liu, Zhenhua Li, Chuize Kong

Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissues

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Qin Tang, Qi Wang, Qiong Zhang, Sheng-Yan Lin, Yanhong Zhu, Xiangliang Yang, An-Yuan Guo

Association between changes in body fat and disease progression after breast cancer surgery is moderated by menopausal status

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Li-Ni Liu, Yung-Chang Lin, Christine Miaskowski, Shin-Cheh Chen, Mei-Ling Chen

Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ζ

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Liang Song, Ewan M. McNeil, Ann-Marie Ritchie, Katy R. Astell, Charlie Gourley, David W. Melton

Process evaluation of health fairs promoting cancer screenings

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Cam Escoffery, Shuting Liang, Kirsten Rodgers, Regine Haardoerfer, Grace Hennessy, Kendra Gilbertson, Natalia I. Heredia, Leticia A. Gatus, Maria E. Fernandez

Photosensitive lichenoid skin reaction to capecitabine

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• Case report

Rena A. Shah, Daniel D. Bennett, Mark E. Burkard

Evaluation of plasma brain-derived neurotrophic factor levels and self-perceived cognitive impairment post-chemotherapy: a longitudinal study

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Terence Ng, Ying Yun Lee, Jung-woo Chae, Angie Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Raymond C. H. Ng, Pat Pak Yan Chu, Chiea Chuen Khor, Han Kiat Ho, Alexandre Chan

Predominance of girls with cancer in families with multiple childhood cancer cases

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Karl-Johan Stjernfelt, Kristoffer von Stedingk, Thomas Wiebe, Lars Hjorth, Håkan Olsson, Ingrid Øra

Effects of interactions between common genetic variants and smoking on colorectal cancer

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Nan Song, Aesun Shin, Hye Soo Jung, Jae Hwan Oh, Jeongseon Kim

Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study

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Tomoyuki Hayashi, Taro Yamashita, Takeshi Terashima, Tsuyoshi Suda, Hikari Okada, Yoshiro Asahina, Takehiro Hayashi, Yasumasa Hara, Kouki Nio, Hajime Sunagozaka, Hajime Takatori, Kuniaki Arai, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Shuichi Kaneko

Risk of second primary cancers in cancer patients treated with cisplatin: a systematic review and meta-analysis of randomized studies

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Fei Liang, Sheng Zhang, Hongxi Xue, Qiang Chen

Cervical cytology and human papillomavirus among asymptomatic healthy volunteers in Vientiane, Lao PDR

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Reika Takamatsu, Viengvansay Nabandith, Vatsana Pholsena, Phouthasone Mounthisone, Katsu Nakasone, Kentarou Ohtake, Naoki Yoshimi

Clinical baseline and prognostic difference of platelet lymphocyte ratio (PLR) in right-sided and let-sided colon cancers

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Lin Yang, Wenzhuo He, Pengfei Kong, Chang Jiang, Qiong Yang, Qiankun Xie, Liang Ping Xia

Dysregulation of Sirtuin 2 (SIRT2) and histone H3K18 acetylation pathways associates with adverse prostate cancer outcomes

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Shivashankar Damodaran, Nathan Damaschke, Joseph Gawdzik, Bing Yang, Cedric Shi, Glenn O. Allen, Wei Huang, John Denu, David Jarrard

Isoprenaline/β2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis

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Yanjie Lu, Qian Xu, Yanzhen Zuo, Lei Liu, Shaochen Liu, Lei Chen, Kang Wang, Yuntao Lei, Xiangyang Zhao, Yuhong Li

A metastatic invasive mole arising from iatrogenic uterus perforation

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• Case report

Yuanming Shen, Xiaoyun Wan, Xing Xie

Comparison of biannual ultrasonography and annual non-contrast liver magnetic resonance imaging as surveillance tools for hepatocellular carcinoma in patients with liver cirrhosis (MAGNUS-HCC): a study protocol

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• Study protocol

Hyun A Kim, Kyung Ah Kim, Joon-Il Choi, Jeong Min Lee, Chang Hee Lee, Tae Wook Kang, Young-Mi Ku, Su Lim Lee, Yang Shin Park, Jeong Hee Yoon, Seong Hyun Kim, Moon Hyung Choi

Bone marrow-derived mesenchymal stem cells induced by inflammatory cytokines produce angiogenetic factors and promote prostate cancer growth

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Ke-Qin Yang, Yan Liu, Qing-Hua Huang, Ning Mo, Qing-Yun Zhang, Qing-Gui Meng, Ji-Wen Cheng

Elevation of tumour markers TGF-β, M2-PK, OV-6 and AFP in hepatocellular carcinoma (HCC)-induced rats and their suppression by microalgae Chlorella vulgaris

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Khaizurin Tajul Arifin, Suhaniza Sulaiman, Suhana Md Saad, Hanafi Ahmad Damanhuri, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof

Utilization and efficacy of second-line targeted therapy in metastatic renal cell carcinoma: data from a national registry

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Radek Lakomy, Alexandr Poprach, Zbynek Bortlicek, Bohuslav Melichar, Renata Chloupkova, Rostislav Vyzula, Milada Zemanova, Katerina Kopeckova, Marek Svoboda, Ondrej Slaby, Igor Kiss, Hana Studentova, Jaroslav Juracek, Ondrej Fiala, Jindrich Kopecky, Jindrich Finek, Ladislav Dusek, Karel Hejduk, Tomas Buchler

N-glycosylation of serum proteins for the assessment of patients with IgD multiple myeloma

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