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Erschienen in:

23.03.2020 | Brachytherapie | CME

Retinoblastom

verfasst von: Prof. Dr. N. Bornfeld, D. Lohmann, N. E. Bechrakis, E. Biewald

Erschienen in: Die Ophthalmologie | Ausgabe 4/2020

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Zusammenfassung

Retinoblastome stellen 6 % aller malignen Tumoren bei Kindern unter einem Alter von 5 Jahren dar, die unbehandelt zu Erblindung der betroffenen Augen und Tod durch Metastasierung führen. Leitsymptome sind Leukokorie und Strabismus, die immer eine Abklärung möglichst innerhalb 1 Woche zum Ausschluss eines Retinoblastoms erfordern. Häufigste Differenzialdiagnosen sind Morbus Coats und PFV („persistent fetal vasculature“) sowie andere intraokulare Tumoren wie insbesondere Astrozytome. Systemische Chemotherapie, ggf. in Kombination mit Laserhyperthermie, lokale Chemotherapie und Brachytherapie sind die wichtigsten Methoden in der bulbuserhaltenden Therapie. Fortgeschrittene Fälle erfordern meist die Enukleation.

https://www.bundesgesundheitsministerium.de/service/begriffe-von-a-z/p/praeimplantationsdiagnostik-pid.html.

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Titel: Retinoblastom
verfasst von: Prof. Dr. N. Bornfeld
D. Lohmann
N. E. Bechrakis
E. Biewald
Publikationsdatum: 23.03.2020
Verlag: Springer Medizin
Schlagwörter: Brachytherapie
Schielen
Schielen
Retinoblastom
Zytostatische Therapie
Strahlentherapie
Retinoblastom
Augenheilkunde
Erschienen in: Die Ophthalmologie / Ausgabe 4/2020
Print ISSN: 2731-720X
Elektronische ISSN: 2731-7218
DOI: https://doi.org/10.1007/s00347-020-01081-x

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