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Zeitschrift

Breast Cancer Research

Breast Cancer Research 1/2017

Ausgabe 1/2017

Inhaltsverzeichnis ( 134 Artikel )

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Mammographic texture and risk of breast cancer by tumor type and estrogen receptor status

Serghei Malkov, John A. Shepherd, Christopher G. Scott, Rulla M. Tamimi, Lin Ma, Kimberly A. Bertrand, Fergus Couch, Matthew R. Jensen, Amir P. Mahmoudzadeh, Bo Fan, Aaron Norman, Kathleen R. Brandt, V. Shane Pankratz, Celine M. Vachon, Karla Kerlikowske

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis

Josee-Lyne Ethier, Danielle Desautels, Arnoud Templeton, Prakesh S. Shah, Eitan Amir

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

18FDG-PET/CT for predicting the outcome in ER+/HER2- breast cancer patients: comparison of clinicopathological parameters and PET image-derived indices including tumor texture analysis

David Groheux, Antoine Martineau, Luis Teixeira, Marc Espié, Patricia de Cremoux, Philippe Bertheau, Pascal Merlet, Charles Lemarignier

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

CCL2-driven inflammation increases mammary gland stromal density and cancer susceptibility in a transgenic mouse model

Xuan Sun, Danielle J. Glynn, Leigh J. Hodson, Cecilia Huo, Kara Britt, Erik W. Thompson, Lucy Woolford, Andreas Evdokiou, Jeffrey W. Pollard, Sarah A. Robertson, Wendy V. Ingman

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Chun-Yu Liu, Ling-Ming Tseng, Jung-Chen Su, Kung-Chi Chang, Pei-Yi Chu, Wei-Tien Tai, Chung-Wai Shiau, Kuen-Feng Chen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Reproductive factors and the risk of triple-negative breast cancer in white women and African-American women: a pooled analysis

Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Lei Duan, Yani Lu, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Jane Sullivan-Halley, Dennis M. Deapen, Michael F. Press, Leslie Bernstein

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

Vandna Shah, Salpie Nowinski, Dina Levi, Irek Shinomiya, Narda Kebaier Ep Chaabouni, Cheryl Gillett, Anita Grigoriadis, Trevor A. Graham, Rebecca Roylance, Michael A. Simpson, Sarah E. Pinder, Elinor J. Sawyer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

Maeve Mullooly, Hannah P. Yang, Roni T. Falk, Sarah J. Nyante, Renata Cora, Ruth M. Pfeiffer, Derek C. Radisky, Daniel W. Visscher, Lynn C. Hartmann, Jodi M. Carter, Amy C. Degnim, Frank Z. Stanczyk, Jonine D. Figueroa, Montserrat Garcia-Closas, Jolanta Lissowska, Melissa A. Troester, Stephen M. Hewitt, Louise A. Brinton, Mark E. Sherman, Gretchen L. Gierach

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells

Craig E. Barcus, Kathleen A. O’Leary, Jennifer L. Brockman, Debra E. Rugowski, Yuming Liu, Nancy Garcia, Menggang Yu, Patricia J. Keely, Kevin W. Eliceiri, Linda A. Schuler

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Parity, hormones and breast cancer subtypes - results from a large nested case-control study in a national screening program

Merete Ellingjord-Dale, Linda Vos, Steinar Tretli, Solveig Hofvind, Isabel dos-Santos-Silva, Giske Ursin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Prevalence of preterm, low birthweight, and small for gestational age delivery after breast cancer diagnosis: a population-based study

Kristin Zeneé Black, Hazel B. Nichols, Eugenia Eng, Diane Louise Rowley

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Non-invasive optical spectroscopic monitoring of breast development during puberty

Lothar Lilge, Mary Beth Terry, Jane Walter, Dushanthi Pinnaduwage, Gord Glendon, Danielle Hanna, Mai-Liis Tammemagi, Angela Bradbury, Saundra Buys, Mary Daly, Esther M. John, Julia A. Knight, Irene L. Andrulis

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Childhood body size and pubertal timing in relation to adult mammographic density phenotype

Minouk J. Schoemaker, Michael E. Jones, Steven Allen, Jean Hoare, Alan Ashworth, Mitch Dowsett, Anthony J. Swerdlow

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Insulin-like growth factor 1 receptor activation promotes mammary gland tumor development by increasing glycolysis and promoting biomass production

Bas ter Braak, Christine L. Siezen, Joo S. Lee, Pooja Rao, Charlotte Voorhoeve, Eytan Ruppin, Jan Willem van der Laan, Bob van de Water

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer

Xin Zhang, Dong Ren, Ling Guo, Lan Wang, Shu Wu, Chuyong Lin, Liping Ye, Jinrong Zhu, Jun Li, Libing Song, Huanxin Lin, Zhenyu He

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer

Giampaolo Bianchini, Astrid Kiermaier, Giulia Valeria Bianchi, Young-Hyuck Im, Tadeusz Pienkowski, Mei-Ching Liu, Ling-Ming Tseng, Mitch Dowsett, Lila Zabaglo, Sarah Kirk, Tania Szado, Jennifer Eng-Wong, Lukas C. Amler, Pinuccia Valagussa, Luca Gianni

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Zhi Hu, Jian-Hua Mao, Christina Curtis, Ge Huang, Shenda Gu, Laura Heiser, Marc E. Lenburg, James E. Korkola, Nora Bayani, Shamith Samarajiwa, Jose A. Seoane, Mark A. Dane, Amanda Esch, Heidi S. Feiler, Nicholas J. Wang, Mary Ann Hardwicke, Sylvie Laquerre, Jeff Jackson, Kenneth W. Wood, Barbara Weber, Paul T. Spellman, Samuel Aparicio, Richard Wooster, Carlos Caldas, Joe W. Gray

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Phase II, randomized, placebo-controlled study of dovitinib in combination with fulvestrant in postmenopausal patients with HR+, HER2− breast cancer that had progressed during or after prior endocrine therapy

Antonino Musolino, Mario Campone, Patrick Neven, Neelima Denduluri, Carlos H. Barrios, Javier Cortes, Kimberly Blackwell, Hatem Soliman, Zsuzsanna Kahan, Hervé Bonnefoi, Matthew Squires, Yong Zhang, Stephanie Deudon, Michael M. Shi, Fabrice André

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Modification of the association between recreational physical activity and survival after breast cancer by promoter methylation in breast cancer-related genes

Lauren E. McCullough, Jia Chen, Yoon Hee Cho, Nikhil K. Khankari, Patrick T. Bradshaw, Alexandra J. White, Susan L. Teitelbaum, Mary Beth Terry, Alfred I. Neugut, Hanina Hibshoosh, Regina M. Santella, Marilie D. Gammon

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Immune profiles of elderly breast cancer patients are altered by chemotherapy and relate to clinical frailty

Jithendra Kini Bailur, Graham Pawelec, Sigrid Hatse, Barbara Brouwers, Ann Smeets, Patrick Neven, Annouschka Laenen, Hans Wildiers, Christopher Shipp

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

EZH2 protein expression in normal breast epithelium and risk of breast cancer: results from the Nurses’ Health Studies

Francisco Beca, Kevin Kensler, Benjamin Glass, Stuart J. Schnitt, Rulla M. Tamimi, Andrew H. Beck

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Circulating gamma-glutamyl transferase and development of specific breast cancer subtypes: findings from the Apolipoprotein Mortality Risk (AMORIS) cohort

Lydia Shackshaft, Mieke Van Hemelrijck, Hans Garmo, Håkan Malmström, Mats Lambe, Niklas Hammar, Göran Walldius, Ingmar Jungner, Wahyu Wulaningsih

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells

Jessalyn M. Ubellacker, Marie-Therese Haider, Molly J. DeCristo, Gloria Allocca, Nicola J. Brown, Daniel P. Silver, Ingunn Holen, Sandra S. McAllister

01.12.2017 | Letter | Ausgabe 1/2017 Open Access

Response to “Lack of association between bovine leukemia virus and breast cancer in Chinese patients”

Gertrude Case Buehring

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms

David J. Lemler, Miranda L. Lynch, Lia Tesfay, Zhiyong Deng, Bibbin T. Paul, Xiaohong Wang, Poornima Hegde, David H. Manz, Suzy V. Torti, Frank M. Torti

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The method of detection of ductal carcinoma in situ has no therapeutic implications: results of a population-based cohort study

Lotte E. Elshof, Michael Schaapveld, Emiel J. Rutgers, Marjanka K. Schmidt, Linda de Munck, Flora E. van Leeuwen, Jelle Wesseling

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer

Jing Xiong, Jiansha Li, Qin Yang, Jun Wang, Tiefen Su, Sheng Zhou

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Anthropometric measures and serum estrogen metabolism in postmenopausal women: the Women’s Health Initiative Observational Study

Hannah Oh, Sally B. Coburn, Charles E. Matthews, Roni T. Falk, Erin S. LeBlanc, Jean Wactawski-Wende, Joshua Sampson, Ruth M. Pfeiffer, Louise A. Brinton, Nicolas Wentzensen, Garnet L. Anderson, JoAnn E. Manson, Chu Chen, Oleg Zaslavsky, Xia Xu, Britton Trabert

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A clinical model for identifying the short-term risk of breast cancer

Mikael Eriksson, Kamila Czene, Yudi Pawitan, Karin Leifland, Hatef Darabi, Per Hall

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry

Logan C. Walker, John F. Pearson, George A. R. Wiggins, Graham G. Giles, John L. Hopper, Melissa C. Southey

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Nighttime eating and breast cancer among Chinese women in Hong Kong

Mengjie Li, Lap Ah Tse, Wing-cheong Chan, Chi-hei Kwok, Siu-lan Leung, Cherry Wu, Wai-cho Yu, Priscilla Ming-yi Lee, Koon-ho Tsang, Sze-hong Law, Roel Vermeulen, Fangyi Gu, Neil E. Caporaso, Ignatius Tak-sun Yu, Feng Wang, Xiaohong Rose Yang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Detecting gene signature activation in breast cancer in an absolute, single-patient manner

E. R. Paquet, R. Lesurf, A. Tofigh, V. Dumeaux, M. T. Hallett

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function

Muge Sarper, Michael D. Allen, Jenny Gomm, Linda Haywood, Julie Decock, Sally Thirkettle, Ahsen Ustaoglu, Shah-Jalal Sarker, John Marshall, Dylan R. Edwards, J. Louise Jones

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Decision making for breast cancer prevention among women at elevated risk

Tasleem J. Padamsee, Celia E. Wills, Lisa D. Yee, Electra D. Paskett

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer

Renée L. Flaherty, Matthew Owen, Aidan Fagan-Murphy, Haya Intabli, David Healy, Anika Patel, Marcus C. Allen, Bhavik A. Patel, Melanie S. Flint

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association between air pollution and mammographic breast density in the Breast Cancer Surveilance Consortium

Lusine Yaghjyan, Robert Arao, Cole Brokamp, Ellen S. O’Meara, Brian L. Sprague, Gabriela Ghita, Patrick Ryan

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo

Ingunn Holen, Jacob Whitworth, Faith Nutter, Alyson Evans, Hannah K. Brown, Diane V. Lefley, Ivana Barbaric, Mark Jones, Penelope D. Ottewell

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Cancer progression by breast tumors with Pit-1-overexpression is blocked by inhibition of metalloproteinase (MMP)-13

Juan Sendon-Lago, Samuel Seoane, Noemi Eiro, Maria A. Bermudez, Manuel Macia, Tomas Garcia-Caballero, Francisco J. Vizoso, Roman Perez-Fernandez

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Honokiol activates AMP-activated protein kinase in breast cancer cells via LKB1-dependent pathway and inhibits breast carcinogenesis

Arumugam Nagalingam, Jack L. Arbiser, Michael Y. Bonner, Neeraj K. Saxena, Dipali Sharma

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: A novel function for p21 Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion

Meiou Dai, Amal A. Al-Odaini, Ani Arakelian, Shafaat A. Rabbani, Suhad Ali, Jean-Jacques Lebrun

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation

Zhaojia Wu, Siqi Shen, Zhiling Zhang, Weiwei Zhang, Wei Xiao

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer

Yi Fang Lee, Lance David Miller, Xiu Bin Chan, Michael A. Black, Brendan Pang, Chee Wee Ong, Manuel Salto-Tellez, Edison T. Liu, Kartiki V. Desai

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion

Meiou Dai, Amal A. Al-Odaini, Nadège Fils-Aimé, Manuel A. Villatoro, Jimin Guo, Ani Arakelian, Shafaat A. Rabbani, Suhad Ali, Jean Jacques Lebrun

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

Miriam Ragle Aure, Valeria Vitelli, Sandra Jernström, Surendra Kumar, Marit Krohn, Eldri U. Due, Tonje Husby Haukaas, Suvi-Katri Leivonen, Hans Kristian Moen Vollan, Torben Lüders, Einar Rødland, Charles J. Vaske, Wei Zhao, Elen K. Møller, Silje Nord, Guro F. Giskeødegård, Tone Frost Bathen, Carlos Caldas, Trine Tramm, Jan Alsner, Jens Overgaard, Jürgen Geisler, Ida R. K. Bukholm, Bjørn Naume, Ellen Schlichting, Torill Sauer, Gordon B. Mills, Rolf Kåresen, Gunhild M. Mælandsmo, Ole Christian Lingjærde, Arnoldo Frigessi, Vessela N. Kristensen, Anne-Lise Børresen-Dale, Kristine K. Sahlberg, OSBREAC

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Endocrine therapy initiation, discontinuation and adherence and breast imaging among 21-gene recurrence score assay-eligible women under age 65

Suzanne C. O’Neill, Claudine Isaacs, Filipa Lynce, Deena Mary Atieh Graham, Calvin Chao, Vanessa B. Sheppard, Yingjun Zhou, Chunfu Liu, Nandini Selvam, Marc D. Schwartz, Arnold L. Potosky

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Overexpression of syndecan-1, MUC-1, and putative stem cell markers in breast cancer leptomeningeal metastasis: a cerebrospinal fluid flow cytometry study

Iole Cordone, Serena Masi, Valentina Summa, Mariantonia Carosi, Antonello Vidiri, Alessandra Fabi, Alessia Pasquale, Laura Conti, Immacolata Rosito, Carmine Maria Carapella, Veronica Villani, Andrea Pace

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Efficacy and safety of everolimus in combination with trastuzumab and paclitaxel in Asian patients with HER2+ advanced breast cancer in BOLERO-1

Masakazu Toi, Zhimin Shao, Sara Hurvitz, Ling-Ming Tseng, Qingyuan Zhang, Kunwei Shen, Donggeng Liu, Jifeng Feng, Binghe Xu, Xiaojia Wang, Keun Seok Lee, Ting Ying Ng, Antonia Ridolfi, Florence Noel-baron, Francois Ringeisen, Zefei Jiang

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Detecting gene signature activation in breast cancer in an absolute, single-patient manner

E. R. Paquet, R. Lesurf, A. Tofigh, V. Dumeaux, M. T. Hallett

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers

Preeti Putcha, Jiyang Yu, Ruth Rodriguez-Barrueco, Laura Saucedo-Cuevas, Patricia Villagrasa, Eva Murga-Penas, Steven N. Quayle, Min Yang, Veronica Castro, David Llobet-Navas, Daniel Birnbaum, Pascal Finetti, Wendy A. Woodward, François Bertucci, Mary L. Alpaugh, Andrea Califano, Jose Silva

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer

Edward P. Carter, James A. Gopsill, Jennifer. J. Gomm, J. Louise Jones, Richard P. Grose

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Cooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases

Cecilia Choy, Khairul I. Ansari, Josh Neman, Sarah Hsu, Matthew J. Duenas, Hubert Li, Nagarajan Vaidehi, Rahul Jandial

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Regular and low-dose aspirin, other non-steroidal anti-inflammatory medications and prospective risk of HER2-defined breast cancer: the California Teachers Study

Christina A. Clarke, Alison J. Canchola, Lisa M. Moy, Susan L. Neuhausen, Nadia T. Chung, James V. Lacey Jr, Leslie Bernstein

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

TIMELESS contributes to the progression of breast cancer through activation of MYC

Limin Chi, Yujiao Zou, Ling Qin, Weifeng Ma, Yanyan Hao, Yao Tang, Rongcheng Luo, Ziqing Wu

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A phase-I study of lapatinib in combination with foretinib, a c-MET, AXL and vascular endothelial growth factor receptor inhibitor, in human epidermal growth factor receptor 2 (HER-2)-positive metastatic breast cancer

Stephen K. Chia, Susan L. Ellard, Mihaela Mates, Stephen Welch, Catalin Mihalcioiu, Wilson H. Miller Jr, Karen Gelmon, Caroline Lohrisch, Vikaash Kumar, Sara Taylor, Linda Hagerman, Rachel Goodwin, Tao Wang, Shingo Sakashita, Ming S. Tsao, Elizabeth Eisenhauer, Penelope Bradbury

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®

Zsuzsanna Varga, Annette Lebeau, Hong Bu, Arndt Hartmann, Frederique Penault-Llorca, Elena Guerini-Rocco, Peter Schraml, Fraser Symmans, Robert Stoehr, Xiaodong Teng, Andreas Turzynski, Reinhard von Wasielewski, Claudia Gürtler, Mark Laible, Kornelia Schlombs, Heikki Joensuu, Thomas Keller, Peter Sinn, Ugur Sahin, John Bartlett, Giuseppe Viale

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ

Mansoureh Sameni, Dora Cavallo-Medved, Omar E. Franco, Anita Chalasani, Kyungmin Ji, Neha Aggarwal, Arulselvi Anbalagan, Xuequn Chen, Raymond R. Mattingly, Simon W. Hayward, Bonnie F. Sloane

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Intratumoral and peritumoral radiomics for the pretreatment prediction of pathological complete response to neoadjuvant chemotherapy based on breast DCE-MRI

Nathaniel M. Braman, Maryam Etesami, Prateek Prasanna, Christina Dubchuk, Hannah Gilmore, Pallavi Tiwari, Donna Plecha, Anant Madabhushi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation

Francisco J. Candido dos Reis, Gordon C. Wishart, Ed M. Dicks, David Greenberg, Jem Rashbass, Marjanka K. Schmidt, Alexandra J. van den Broek, Ian O. Ellis, Andrew Green, Emad Rakha, Tom Maishman, Diana M. Eccles, Paul D. P. Pharoah

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Rapid evaporative ionisation mass spectrometry of electrosurgical vapours for the identification of breast pathology: towards an intelligent knife for breast cancer surgery

Edward R. St John, Julia Balog, James S. McKenzie, Merja Rossi, April Covington, Laura Muirhead, Zsolt Bodai, Francesca Rosini, Abigail V. M. Speller, Sami Shousha, Rathi Ramakrishnan, Ara Darzi, Zoltan Takats, Daniel R. Leff

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models

Amir Bahreini, Zheqi Li, Peilu Wang, Kevin M. Levine, Nilgun Tasdemir, Lan Cao, Hazel M. Weir, Shannon L. Puhalla, Nancy E. Davidson, Andrew M. Stern, David Chu, Ben Ho Park, Adrian V. Lee, Steffi Oesterreich

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Age-related terminal duct lobular unit involution in benign tissues from Chinese breast cancer patients with luminal and triple-negative tumors

Changyuan Guo, Hyuna Sung, Shan Zheng, Jennifer Guida, Erni Li, Jing Li, Nan Hu, Joseph Deng, Jonine D. Figueroa, Mark E. Sherman, Gretchen L. Gierach, Ning Lu, Xiaohong R. Yang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis

Zhengyu Jiang, Carolyn M. Slater, Yan Zhou, Karthik Devarajan, Karen J. Ruth, Yueran Li, Kathy Q. Cai, Mary Daly, Xiaowei Chen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data

Giorgio E. M. Melloni, Luca Mazzarella, Loris Bernard, Margherita Bodini, Anna Russo, Lucilla Luzi, Pier Giuseppe Pelicci, Laura Riva

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers

Shoko Vos, Cathy Beatrice Moelans, Paul Joannes van Diest

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Molecular characterization of breast cancer cell lines through multiple omic approaches

Shari E. Smith, Paul Mellor, Alison K. Ward, Stephanie Kendall, Megan McDonald, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Scott Napper, Deborah H. Anderson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Follistatin is a metastasis suppressor in a mouse model of HER2-positive breast cancer

Darcie D. Seachrist, Steven T. Sizemore, Emhonta Johnson, Fadi W. Abdul-Karim, Kristen L. Weber Bonk, Ruth A. Keri

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The effect of volumetric breast density on the risk of screen-detected and interval breast cancers: a cohort study

Johanna O. P. Wanders, Katharina Holland, Nico Karssemeijer, Petra H. M. Peeters, Wouter B. Veldhuis, Ritse M. Mann, Carla H. van Gils

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Tightly controlled MRTF-A activity regulates epithelial differentiation during formation of mammary acini

Anja Seifert, Guido Posern

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pubertal development in girls by breast cancer family history: the LEGACY girls cohort

Mary Beth Terry, Theresa H. M. Keegan, Lauren C. Houghton, Mandy Goldberg, Irene L. Andrulis, Mary B. Daly, Saundra S. Buys, Ying Wei, Alice S. Whittemore, Angeline Protacio, Angela R. Bradbury, Wendy K. Chung, Julia A. Knight, Esther M. John

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Minako Sakurai, Yasuhiro Miki, Kiyoshi Takagi, Takashi Suzuki, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Evaluation of invasive breast cancer samples using a 12-chemokine gene expression score: correlation with clinical outcomes

Sangeetha Prabhakaran, Victoria T. Rizk, Zhenjun Ma, Chia-Ho Cheng, Anders E. Berglund, Dominico Coppola, Farah Khalil, James J. Mulé, Hatem H. Soliman

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

miR-629-3p may serve as a novel biomarker and potential therapeutic target for lung metastases of triple-negative breast cancer

Jin Wang, Cailu Song, Hailin Tang, Chao Zhang, Jun Tang, Xing Li, Bo Chen, Xiaoming Xie

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

MicroRNA-200c and microRNA- 141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

Guangxin Zhang, Wei Zhang, Bingjin Li, Erica Stringer-Reasor, Chengjing Chu, Liyan Sun, Sejong Bae, Dongquan Chen, Shi Wei, Kenneth Jiao, Wei-Hsiung Yang, Ranji Cui, Runhua Liu, Lizhong Wang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis

Meghan Morrison Joly, Michelle M. Williams, Donna J. Hicks, Bayley Jones, Violeta Sanchez, Christian D. Young, Dos D. Sarbassov, William J. Muller, Dana Brantley-Sieders, Rebecca S. Cook

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Neoadjuvant radiotherapy of early-stage breast cancer and long-term disease-free survival

Jan Poleszczuk, Kimberly Luddy, Lu Chen, Jae K. Lee, Louis B. Harrison, Brian J. Czerniecki, Hatem Soliman, Heiko Enderling

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours

Mira M. Shenouda, Amy Gillgrass, Tina Nham, Richard Hogg, Amanda J. Lee, Marianne V. Chew, Mahsa Shafaei, Craig Aarts, Dean A. Lee, John Hassell, Anita Bane, Sukhbinder Dhesy-Thind, Ali A. Ashkar

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Maternal intake of high n-6 polyunsaturated fatty acid diet during pregnancy causes transgenerational increase in mammary cancer risk in mice

Nguyen M. Nguyen, Fabia de Oliveira Andrade, Lu Jin, Xiyuan Zhang, Madisa Macon, M. Idalia Cruz, Carlos Benitez, Bryan Wehrenberg, Chao Yin, Xiao Wang, Jianhua Xuan, Sonia de Assis, Leena Hilakivi-Clarke

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The footprint of the ageing stroma in older patients with breast cancer

Barbara Brouwers, Debora Fumagalli, Sylvain Brohee, Sigrid Hatse, Olivier Govaere, Giuseppe Floris, Kathleen Van den Eynde, Yacine Bareche, Patrick Schöffski, Ann Smeets, Patrick Neven, Diether Lambrechts, Christos Sotiriou, Hans Wildiers

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis

Igor Bado, Fotis Nikolos, Gayani Rajapaksa, Wanfu Wu, Jessica Castaneda, Savitri Krishnamurthy, Paul Webb, Jan-Åke Gustafsson, Christoforos Thomas

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Intratumoral and peritumoral radiomics for the pretreatment prediction of pathological complete response to neoadjuvant chemotherapy based on breast DCE-MRI

Nathaniel M. Braman, Maryam Etesami, Prateek Prasanna, Christina Dubchuk, Hannah Gilmore, Pallavi Tiwari, Donna Plecha, Anant Madabhushi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

Kevin C. Johnson, E. Andres Houseman, Jessica E. King, Brock C. Christensen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Early pregnancy sex steroids during primiparous pregnancies and maternal breast cancer: a nested case–control study in the Northern Sweden Maternity Cohort

Renée T. Fortner, Eglé Tolockiene, Helena Schock, Husam Oda, Hans-Åke Lakso, Göran Hallmans, Rudolf Kaaks, Paolo Toniolo, Anne Zeleniuch-Jacquotte, Kjell Grankvist, Eva Lundin

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population

Anne S. Reiner, Charles F. Lynch, Julia S. Sisti, Esther M. John, Jennifer D. Brooks, Leslie Bernstein, Julia A. Knight, Li Hsu, Patrick Concannon, Lene Mellemkjær, Marc Tischkowitz, Robert W. Haile, Ronglai Shen, Kathleen E. Malone, Meghan Woods, Xiaolin Liang, Monica Morrow, Jonine L. Bernstein, on behalf of WECARE Study Collaborative Group

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Body size in early life and risk of breast cancer

Md. Shajedur Rahman Shawon, Mikael Eriksson, Jingmei Li

01.12.2017 | Editorial | Ausgabe 1/2017 Open Access

Consistency, now what?

Mary Beth Terry

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin

H. J. Hugo, N. P. A. D. Gunasinghe, B. G. Hollier, T. Tanaka, T. Blick, A. Toh, P. Hill, C. Gilles, M. Waltham, E. W. Thompson

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies

Sinead Toomey, Alexander J. Eustace, Joanna Fay, Katherine M. Sheehan, Aoife Carr, Malgorzata Milewska, Stephen F. Madden, Ausra Teiserskiene, Elaine W. Kay, Norma O’Donovan, William Gallagher, Liam Grogan, Oscar Breathnach, Janice Walshe, Catherine Kelly, Brian Moulton, M. John Kennedy, Guiseppe Gullo, Arnold D. Hill, Colm Power, Deirdre Duke, Niamh Hambly, John Crown, Bryan T. Hennessy

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

AKT1low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer

Sheheryar Kabraji, Xavier Solé, Ying Huang, Clyde Bango, Michaela Bowden, Aditya Bardia, Dennis Sgroi, Massimo Loda, Sridhar Ramaswamy

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer

Komal Jhaveri, Rui Wang, Eleonora Teplinsky, Sarat Chandarlapaty, David Solit, Karen Cadoo, James Speyer, Gabriella D’Andrea, Sylvia Adams, Sujata Patil, Sofia Haque, Tara O’Neill, Kent Friedman, Francisco J. Esteva, Clifford Hudis, Shanu Modi

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade

Janet L. Martin, Sohel M. Julovi, Mike Z. Lin, Hasanthi C. de Silva, Frances M. Boyle, Robert C. Baxter

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance

Vasiliki Pelekanou, Daniel E. Carvajal-Hausdorf, Mehmet Altan, Brad Wasserman, Cristobal Carvajal-Hausdorf, Hallie Wimberly, Jason Brown, Donald Lannin, Lajos Pusztai, David L. Rimm

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Concurrent antitumor and bone-protective effects of everolimus in osteotropic breast cancer

Andrew J. Browne, Marie L. Kubasch, Andy Göbel, Peyman Hadji, David Chen, Martina Rauner, Friedrich Stölzel, Lorenz C. Hofbauer, Tilman D. Rachner

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Selinexor (KPT-330) demonstrates anti-tumor efficacy in preclinical models of triple-negative breast cancer

Natalia Paez Arango, Erkan Yuca, Ming Zhao, Kurt W. Evans, Stephen Scott, Charissa Kim, Ana Maria Gonzalez-Angulo, Filip Janku, Naoto T. Ueno, Debu Tripathy, Argun Akcakanat, Aung Naing, Funda Meric-Bernstam

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

White blood cell DNA methylation and risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)

Susan R. Sturgeon, J. Richard Pilsner, Kathleen F. Arcaro, Kaoru Ikuma, Haotian Wu, Soon-Mi Kim, Nayha Chopra-Tandon, Adam R. Karpf, Regina G. Ziegler, Catherine Schairer, Raji Balasubramanian, David A. Reckhow

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion

Sisi Qin, James N. Ingle, Mohan Liu, Jia Yu, D. Lawrence Wickerham, Michiaki Kubo, Richard M. Weinshilboum, Liewei Wang

01.12.2017 | Meeting report | Ausgabe 1/2017 Open Access

The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Katrin E. Wiese, Romain J. Amante, Maria dM. Vivanco, Mohamed Bentires-Alj, Richard D. Iggo

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Combining quantitative and qualitative breast density measures to assess breast cancer risk

Karla Kerlikowske, Lin Ma, Christopher G. Scott, Amir P. Mahmoudzadeh, Matthew R. Jensen, Brian L. Sprague, Louise M. Henderson, V. Shane Pankratz, Steven R. Cummings, Diana L. Miglioretti, Celine M. Vachon, John A. Shepherd

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Assessment of the prognostic role of a 94-single nucleotide polymorphisms risk score in early breast cancer in the SIGNAL/PHARE prospective cohort: no correlation with clinico-pathological characteristics and outcomes

Elsa Curtit, Xavier Pivot, Julie Henriques, Sophie Paget-Bailly, Pierre Fumoleau, Maria Rios, Hervé Bonnefoi, Thomas Bachelot, Patrick Soulié, Christelle Jouannaud, Hugues Bourgeois, Thierry Petit, Isabelle Tennevet, David Assouline, Marie-Christine Mathieu, Jean-Philippe Jacquin, Sandrine Lavau-Denes, Ariane Darut-Jouve, Jean-Marc Ferrero, Carole Tarpin, Christelle Lévy, Valérie Delecroix, Véronique Trillet-Lenoir, Oana Cojocarasu, Jérôme Meunier, Jean-Yves Pierga, Pierre Kerbrat, Céline Faure-Mercier, Hélène Blanché, Mourad Sahbatou, Anne Boland, Delphine Bacq, Céline Besse, Gilles Thomas, Jean-François Deleuze, Iris Pauporté, Gilles Romieu, David G. Cox

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting

Tesa M. Severson, Denise M. Wolf, Christina Yau, Justine Peeters, Diederik Wehkam, Philip C. Schouten, Suet-Feung Chin, Ian J. Majewski, Magali Michaut, Astrid Bosma, Bernard Pereira, Tycho Bismeijer, Lodewyk Wessels, Carlos Caldas, René Bernards, Iris M. Simon, Annuska M. Glas, Sabine Linn, Laura van ‘t Veer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Tissue-based associations of mammographic breast density with breast stem cell markers

Lusine Yaghjyan, Ethan Stoll, Karthik Ghosh, Christopher G. Scott, Matthew R. Jensen, Kathleen R. Brandt, Daniel Visscher, Celine M. Vachon

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Association of pre-chemotherapy peripheral blood pro-inflammatory and coagulation factors with reduced relative dose intensity in women with breast cancer

Yuan Yuan, Nilesh Vora, Can-Lan Sun, Daneng Li, Enrique Soto-Perez-de-Celis, Joanne Mortimer, The-hang Luu, George Somlo, James Waisman, David Smith, Joseph Chao, Vani Katheria, Timothy Synold, Vivi Tran, Shu Mi, Abrahm Levi, Anait Arsenyan, Jennifer Choi, Laura Zavala, Susan Yost, Arti Hurria

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Pathobiology of the 129:Stat1 −/− mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotype

Hidetoshi Mori, Jane Q. Chen, Robert D. Cardiff, Zsófia Pénzváltó, Neil E. Hubbard, Louis Schuetter, Russell C. Hovey, Josephine F. Trott, Alexander D. Borowsky

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Breast Tissue Organisation and its Association with Breast Cancer Risk

Maya Alsheh Ali, Kamila Czene, Louise Eriksson, Per Hall, Keith Humphreys

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

SPEN, a new player in primary cilia formation and cell migration in breast cancer

Stéphanie Légaré, Catherine Chabot, Mark Basik

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation

Michelle M. Williams, David B. Vaught, Meghan Morrison Joly, Donna J. Hicks, Violeta Sanchez, Philip Owens, Bushra Rahman, David L. Elion, Justin M. Balko, Rebecca S. Cook

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Contrast-enhanced spectral mammography in neoadjuvant chemotherapy monitoring: a comparison with breast magnetic resonance imaging

Valentina Iotti, Sara Ravaioli, Rita Vacondio, Chiara Coriani, Sabrina Caffarri, Roberto Sghedoni, Andrea Nitrosi, Moira Ragazzi, Elisa Gasparini, Cristina Masini, Giancarlo Bisagni, Giuseppe Falco, Guglielmo Ferrari, Luca Braglia, Alberto Del Prato, Ivana Malavolti, Vladimiro Ginocchi, Pierpaolo Pattacini

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors

Imke H. Bartelink, Brendan Prideaux, Gregor Krings, Lisa Wilmes, Pei Rong Evelyn Lee, Pan Bo, Byron Hann, Jean-Philippe Coppé, Diane Heditsian, Lamorna Swigart-Brown, Ella F. Jones, Sergey Magnitsky, Ron J Keizer, Niels de Vries, Hilde Rosing, Nela Pawlowska, Scott Thomas, Mallika Dhawan, Rahul Aggarwal, Pamela N. Munster, Laura J. Esserman, Weiming Ruan, Alan H. B. Wu, Douglas Yee, Véronique Dartois, Radojka M. Savic, Denise M. Wolf, Laura van ’t Veer

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Alcohol consumption and breast tumor gene expression

Jun Wang, Yujing J. Heng, A. Heather Eliassen, Rulla M. Tamimi, Aditi Hazra, Vincent J. Carey, Christine B. Ambrosone, Victor P. de Andrade, Adam Brufsky, Fergus J. Couch, Tari A. King, Francesmary Modugno, Celine M. Vachon, David J. Hunter, Andrew H. Beck, Susan E. Hankinson

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Effect of neoadjuvant chemotherapy on tumor-infiltrating lymphocytes and PD-L1 expression in breast cancer and its clinical significance

Vasiliki Pelekanou, Daniel E. Carvajal-Hausdorf, Mehmet Altan, Brad Wasserman, Cristobal Carvajal-Hausdorf, Hallie Wimberly, Jason Brown, Donald Lannin, Lajos Pusztai, David L. Rimm

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers

Tomas Baldassarre, Peter Truesdell, Andrew W. Craig

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

Cheng-Fen Tu, Meng-Ying Wu, Yuh-Charn Lin, Reiji Kannagi, Ruey-Bing Yang

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

Stephan Bernhardt, Michaela Bayerlová, Martina Vetter, Astrid Wachter, Devina Mitra, Volker Hanf, Tilmann Lantzsch, Christoph Uleer, Susanne Peschel, Jutta John, Jörg Buchmann, Edith Weigert, Karl-Friedrich Bürrig, Christoph Thomssen, Ulrike Korf, Tim Beissbarth, Stefan Wiemann, Eva Johanna Kantelhardt

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study

Katherine Lawler, Efterpi Papouli, Cristina Naceur-Lombardelli, Anca Mera, Kayleigh Ougham, Andrew Tutt, Siker Kimbung, Ingrid Hedenfalk, Jun Zhan, Hongquan Zhang, Richard Buus, Mitch Dowsett, Tony Ng, Sarah E. Pinder, Peter Parker, Lars Holmberg, Cheryl E. Gillett, Anita Grigoriadis, Arnie Purushotham

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

A novel and fully automated mammographic texture analysis for risk prediction: results from two case-control studies

Chao Wang, Adam R. Brentnall, Jack Cuzick, Elaine F. Harkness, D. Gareth Evans, Susan Astley

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Roles of BCCIP deficiency in mammary tumorigenesis

Roberto Droz-Rosario, Huimei Lu, Jingmei Liu, Ning-Ang Liu, Shridar Ganesan, Bing Xia, Bruce G. Haffty, Zhiyuan Shen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Addition of T2-guided optical tomography improves noncontrast breast magnetic resonance imaging diagnosis

Jinchao Feng, Junqing Xu, Shudong Jiang, Hong Yin, Yan Zhao, Jiang Gui, Ke Wang, Xiuhua Lv, Fang Ren, Brian W. Pogue, Keith D. Paulsen

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

Smoking and risk of breast cancer in the Generations Study cohort

Michael E. Jones, Minouk J. Schoemaker, Lauren B. Wright, Alan Ashworth, Anthony J. Swerdlow

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study

Olivier Brouckaert, Anja Rudolph, Annouschka Laenen, Renske Keeman, Manjeet K. Bolla, Qin Wang, Adelheid Soubry, Hans Wildiers, Irene L. Andrulis, Volker Arndt, Matthias W. Beckmann, Javier Benitez, Carl Blomqvist, Stig E. Bojesen, Hiltrud Brauch, Paul Brennan, Hermann Brenner, Georgia Chenevix-Trench, Ji-Yeob Choi, Sten Cornelissen, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mikael Eriksson, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Graham G. Giles, Anna González-Neira, Pascal Guénel, Per Hall, Antoinette Hollestelle, John L. Hopper, Hidemi Ito, Michael Jones, Daehee Kang, Julia A. Knight, Veli-Matti Kosma, Jingmei Li, Annika Lindblom, Jenna Lilyquist, Artitaya Lophatananon, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Keitaro Matsuo, Kenneth Muir, Heli Nevanlinna, Paolo Peterlongo, Katri Pylkäs, Suleeporn Saajrang, Caroline Seynaeve, Chen-Yang Shen, Xiao-Ou Shu, Melissa C. Southey, Anthony Swerdlow, Soo-Hwang Teo, Rob A. E. M. Tollenaar, Thérèse Truong, Chiu-chen Tseng, Alexandra J. van den Broek, Carolien H. M. van Deurzen, Robert Winqvist, Anna H. Wu, Cheng Har Yip, Jyh-Cherng Yu, Wei Zheng, Roger L. Milne, Paul D. P. Pharoah, Douglas F. Easton, Marjanka K. Schmidt, Montserrat Garcia-Closas, Jenny Chang-Claude, Diether Lambrechts, Patrick Neven, kConFab

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up

Hege O. Ohnstad, Elin Borgen, Ragnhild S. Falk, Tonje G. Lien, Marit Aaserud, My Anh T. Sveli, Jon A. Kyte, Vessela N. Kristensen, Gry A. Geitvik, Ellen Schlichting, Erik A. Wist, Therese Sørlie, Hege G. Russnes, Bjørn Naume

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells

Derek F. Amanatullah, John S. Tamaresis, Pauline Chu, Michael H. Bachmann, Nhat M. Hoang, Deborah Collyar, Aaron T. Mayer, Robert B. West, William J. Maloney, Christopher H. Contag, Bonnie L. King

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells

Robert Hromas, Hyun-Suk Kim, Gurjit Sidhu, Elizabeth Williamson, Aruna Jaiswal, Taylor A. Totterdale, Jocelyn Nole, Suk-Hee Lee, Jac A. Nickoloff, Kimi Y. Kong

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Serum thymidine kinase 1 activity as a pharmacodynamic marker of cyclin-dependent kinase 4/6 inhibition in patients with early-stage breast cancer receiving neoadjuvant palbociclib

Nusayba Bagegni, Shana Thomas, Ning Liu, Jingqin Luo, Jeremy Hoog, Donald W. Northfelt, Matthew P. Goetz, Andres Forero, Mattias Bergqvist, Jakob Karen, Magnus Neumüller, Edward M. Suh, Zhanfang Guo, Kiran Vij, Souzan Sanati, Matthew Ellis, Cynthia X. Ma

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Residential particulate matter and distance to roadways in relation to mammographic density: results from the Nurses’ Health Studies

Natalie C. DuPre, Jaime E. Hart, Kimberly A. Bertrand, Peter Kraft, Francine Laden, Rulla M. Tamimi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

Thomas Helland, Nina Henne, Ersilia Bifulco, Bjørn Naume, Elin Borgen, Vessela N. Kristensen, Jan T. Kvaløy, Timothy L. Lash, Grethe I. G. Alnæs, Ron H. van Schaik, Emiel A. M. Janssen, Steinar Hustad, Ernst A. Lien, Gunnar Mellgren, Håvard Søiland

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Influence of breast compression pressure on the performance of population-based mammography screening

Katharina Holland, Ioannis Sechopoulos, Ritse M. Mann, Gerard J. den Heeten, Carla H. van Gils, Nico Karssemeijer

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events

Lucy C. de Jong, Simone Cree, Vanessa Lattimore, George A. R. Wiggins, Amanda B. Spurdle, Allison Miller, Martin A. Kennedy, Logan C. Walker, kConFab Investigators

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity

Tamara Chamberlin, Joseph V. D’Amato, Lisa M. Arendt

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment

Ernestina M. De Francesco, Andrew H. Sims, Marcello Maggiolini, Federica Sotgia, Michael P. Lisanti, Robert B. Clarke

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study

Jia Yu, Bo Qin, Ann M. Moyer, Jason P. Sinnwell, Kevin J. Thompson, John A. Copland III, Laura A. Marlow, James L. Miller, Ping Yin, Bowen Gao, Katherine Minter-Dykhouse, Xiaojia Tang, Sarah A. McLaughlin, Alvaro Moreno-Aspitia, Anthony Schweitzer, Yan Lu, Jason Hubbard, Donald W. Northfelt, Richard J. Gray, Katie Hunt, Amy L. Conners, Vera J. Suman, Krishna R. Kalari, James N. Ingle, Zhenkun Lou, Daniel W. Visscher, Richard Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Liewei Wang

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Race-associated biological differences among luminal A and basal-like breast cancers in the Carolina Breast Cancer Study

Humberto Parada Jr, Xuezheng Sun, Jodie M. Fleming, ClarLynda R. Williams-DeVane, Erin L. Kirk, Linnea T. Olsson, Charles M. Perou, Andrew F. Olshan, Melissa A. Troester

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Phosphoproteomics reveals network rewiring to a pro-adhesion state in annexin-1-deficient mammary epithelial cells

Asfa Alli-Shaik, Sheena Wee, Lina H. K. Lim, Jayantha Gunaratne

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer

Hao-Yi Li, Jui-Lin Liang, Yao-Lung Kuo, Hao-Hsien Lee, Marcus J. Calkins, Hong-Tai Chang, Forn-Chia Lin, Yu-Chia Chen, Tai-I Hsu, Michael Hsiao, Luo-Ping Ger, Pei-Jung Lu

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Association between mammographic breast density and histologic features of benign breast disease

Karthik Ghosh, Robert A. Vierkant, Ryan D. Frank, Stacey Winham, Daniel W. Visscher, Vernon S. Pankratz, Christopher G. Scott, Kathleen Brandt, Mark E. Sherman, Derek C. Radisky, Marlene H. Frost, Lynn C. Hartmann, Amy C. Degnim, Celine M. Vachon

01.12.2017 | Research Article | Ausgabe 1/2017 Open Access

Use of prescription drugs and risk of postoperative red blood cell transfusion in breast cancer patients: a Danish population-based cohort study

Anne Marie L. Thomsen, Alma B. Pedersen, Nickolaj R. Kristensen, Bjarne Kuno Møller, Christian Erikstrup, Peer M. Christiansen, Mette Nørgaard, Deirdre Cronin-Fenton

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