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European Child & Adolescent Psychiatry

Erschienen in:

01.07.2007 | EDITORIAL

Co-existence of tic disorders and attention-deficit/hyperactivity disorder-recent advances in understanding and treatment

verfasst von: Prof. Dr. Aribert Rothenberger, Veit Roessner, Tobias Banaschewski, James F. Leckman

Erschienen in: European Child & Adolescent Psychiatry | Sonderheft 1/2007

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Abstract

In daily clinical practice of child psychiatry tic disorders (TD) and attention-deficit/hyperactivity disorder (ADHD) as well as their co-existence are common and need careful evidence-based approaches in differential diagnostics and treatment choice. Hence, their relationship at different levels (e.g., psychopathology, neuropsychology, neurobiology, treatment) needs to be elucidated in more detail. The articles of this supplement deal with this subject. It is unclear if TD + ADHD represents an own clinical entity and which component (TD vs. ADHD) is most important in case of co-existence with respect to accompanying problems like emotional or cognitive disturbances. This editorial gives a short overview of the essential research topics concerning TD + ADHD and shows where (in this ECAP supplement and other literature) empirically based answers can be found. Probably, the identification of separate or common “endophenotypes” for TD-only, ADHD-only and for TD + ADHD would help to sort out the complexities and this supplement may nurture such a perspective of future research for a better understanding and treatment of youths with TD + ADHD and their families.

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Banaschewski T, Neale BM, Rothenberger A, Roessner V (2007) Comorbidity of tic disorders and ADHD – conceptual and methodological considerations. Eur Child Adolesc Psychiatry 16(Suppl 1):I/5–I/14

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10.

Döpfner M, Roessner V, Rothenberger A (2007) Tic-Störungen. Göttingen, Hogrefe. (in press)

11.

Erenberg G (2005) The relationship between Tourette syndrome, attention deficit hyperactivity disorder, and stimulant medication: a critical review. Semin Pediatr Neurol 12:217–221PubMedCrossRef

12.

Freeman R and the Tourette Syndrome International Database Consortium (2007) Tic disorders and ADHD – answers from a world-wide clinical data set on Tourette Syndrome. Eur Child Adolesc Psychiatry 16(Suppl 1):I/15–I/23

13.

Gillberg C, Gillberg JC, Rasmussen P, Kadesjö B, Södertröm H, Råstam M, Johnson M, Rothenberger A, Niklasson L (2004) Co-existing disorders in ADHD – implications for diagnosis and intervention. Eur Child Adolesc Psychiatry 13(Suppl 1):80–92

14.

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Kadesjö B, Gillberg C (2001) The comorbidity of ADHD in the general population of Swedish school-age children. J Child Psychol Psychiatry 42:487–492PubMedCrossRef

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Khalifa N, von Knorring AL (2006) Psychopathology in a Swedish population of school children with tic disorders. J Am Acad Child Adolesc Psychiatry 45:1346–1353PubMedCrossRef

17.

Kirov R, Banaschewski T, Uebel H, Kinkelbur J, Rothenberger A (2007b) REM-sleep alterations in children with tic disorder and ADHD comorbidity – impact of hypermotor symptoms. Eur Child Adolesc Psychiatry 16(Suppl 1):I/45–I/50CrossRef

18.

Kirov R, Kinkelbur J, Banaschewski T, Rothenberger A (2007a) Sleep patterns in children with attention-deficit/hyperactivity disorder, tic disorder and comorbidity. J Child Psychol Psychiatry 48:561–570PubMedCrossRef

19.

Leckman JF, Vaccarino FM, Kalanithi PS, Rothenberger A (2006) Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations. J Child Psychol Psychiatry 47:537–550PubMedCrossRef

20.

Marsh R, Alexander GM, Packard MG, Zhu H, Wingard JC, Quackenbush G, Peterson BS (2004) Habit learning in Tourette syndrome: a translational neuroscience approach to a developmental psychopathology. Arch Gen Psychiatry 61(12):1259–1268PubMedCrossRef

21.

Moll GH, Heinrich H, Trott GE, Wirth S, Bock N, Rothenberger A (2001) Children with comorbid attention-deficit hyperactivity disorder and tic disorder: evidence for additive inhibitory deficits within the motor system. Ann Neurol 49:393–396PubMedCrossRef

22.

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24.

Plessen KJ, Royal JM, Peterson BS (2007) Neuroimaging of tic disorders with coexisting attention deficit hyperactivity disorder. Eur Child Adolesc Psychiatry 16(Suppl 1):I/60–I/70

25.

Poncin Y, Sukhodolsky D, McGuire J, Scahill L (2007) The drug and non-drug treatment of children with ADHD and tic disorders. Eur Child Adolesc Psychiatry 16(Suppl 1):I/78–I/88

26.

Robertson MM (2006) Attention deficit hyperactivity disorder, tics and Tourette’s syndrome: the relationship and treatment implications. A commentary. Eur Child Adolesc Psychiatry 15:1–11PubMedCrossRef

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Roessner V, Becker A, Banaschewski T, Rothenberger A (2006) Psychopathological profile in children with chronic tic disorder and co-existing ADHD: additive effects. J Abnorm Child Psychol 35:79–85PubMedCrossRef

28.

Roessner V, Becker A, Banaschewksi T, Rothenberger A (2007b) Executive functions in children with chronic tic disorders with/without ADHD – new insights. Eur Child Adolesc Psychiatry 16(Suppl 1):I/36–I/44

29.

Roessner V, Becker A, Freeman R, Rothenberger A and the Tourette Syndrome International Database Consortium (2007a) Developmental psychopathology of children and adolescents with Tourette syndrome - impact of ADHD. Eur Child Adolesc Psychiatry 16(Suppl 1):I/24–I/35

30.

Rothenberger A, Banaschewski T (2006) Tic-Disorders. In: Gillberg C, Harrington R, Steinhausen HC (eds) A Clinican’s handbook of child and adolescent psychiatry. Cambridge University Press, pp 598–624

31.

Rothenberger A, Banaschewski T, Heinrich H, Moll GH, Schmidt MH, van’t Klooster B (2000) Comorbidity in ADHD children: coexisting conduct disorder but not tic disorder accompanied by brain electrical deficit in an auditiory selective attention task. Eur Arch Psychiat Clin Neurosci 250:101–110CrossRef

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35.

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36.

Steinhausen HC, Novik TS, Baldursson G, Curatolo P, Lorenzo MJ, Rodrigues Pereira R, Ralston SJ, Rothenberger A ADORE Study Group (2006) Co-existing psychiatric problems in ADHD in the ADORE cohort. Eur Child Adolesc Psychiatry 15(Suppl 1):i25–i29CrossRef

37.

Stewart SE, Illmann C, Geller DA, Leckman JF, King R, Pauls DL (2006) A controlled family study of attention-deficit/hyperactivity disorder and Tourette’s disorder. J Am Acad Child Adolesc Psychiatry 45:1354–1362PubMedCrossRef

38.

Sukhodolsky D, Leckman JF, Rothenberger A, Scahill L (2007) The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and ADHD. Eur Child Adolesc Psychiatry 16(Suppl 1):I/51–I/59

39.

Sukhodolsky DG, Scahill L, Zhang H, Peterson BS, King RA, Lombroso PJ, Katsovich L, Findley D, Leckman JF (2003) Disruptive behavior in children with Tourette’s syndrome: association with ADHD comorbidity, tic severity, and functional impairment. J Am Acad Child Adolesc Psychiatry 42:98–105PubMedCrossRef

40.

Taylor E, Döpfner M, Sergeant J, Asherson P, Banaschewski T, Buitelaar J, Coghill D, Danckaerts M, Rothenberger A, Sonuga-Barke E, Steinhausen HC, Zuddas A (2004) European clinical guidelines for hyperkinetic disorder – first upgrade. Eur Child Adolesc Psychiatry 13(Suppl 1):7–30

41.

Yordanova J, Heinrich H, Kolev V, Rothenberger A (2006) Increased event-related theta activity as a psychophysiological marker of comorbidity in children with tics and attention-deficit/hyperactivity disorders. NeuroImage 32:940–955PubMedCrossRef

42.

Zhu Y, Leung KM, Liu P, Zhou M, Su L (2006) Comorbid behavioural problems in Tourette’s syndrome are positive correlated with the severity of symptoms. Aust N Z J Psychiatry 40:67–73PubMedCrossRef

Titel: Co-existence of tic disorders and attention-deficit/hyperactivity disorder-recent advances in understanding and treatment
verfasst von: Prof. Dr. Aribert Rothenberger
Veit Roessner
Tobias Banaschewski
James F. Leckman
Publikationsdatum: 01.07.2007
Verlag: Steinkopff-Verlag
Erschienen in: European Child & Adolescent Psychiatry / Ausgabe Sonderheft 1/2007
Print ISSN: 1018-8827
Elektronische ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-007-1001-9

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