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Zeitschrift

EJNMMI Research

EJNMMI Research 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 113 Artikel )

01.12.2018 | Preliminary research | Ausgabe 1/2018 Open Access

Positron emission tomography-magnetic resonance imaging (PET-MRI) for response assessment after radiation therapy of cervical carcinoma: a pilot study

J. E. Mongula, F. C. H. Bakers, S. Vöö, L. Lutgens, T. van Gorp, R. F. P. M. Kruitwagen, B. F. M. Slangen

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Prognostic value of simultaneous 18F-FDG PET/MRI using a combination of metabolo-volumetric parameters and apparent diffusion coefficient in treated head and neck cancer

Yong-il Kim, Gi Jeong Cheon, Seo Young Kang, Jin Chul Paeng, Keon Wook Kang, Dong Soo Lee, June-Key Chung

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Diagnostic implications of a small-voxel reconstruction for loco-regional lymph node characterization in breast cancer patients using FDG-PET/CT

Daniëlle Koopman, Jorn A. van Dalen, Hester Arkies, Ad H. J. Oostdijk, Anne Brecht Francken, Jos Bart, Cornelis H. Slump, Siert Knollema, Pieter L. Jager

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

A novel genomic signature predicting FDG uptake in diverse metastatic tumors

Aurora Crespo-Jara, Maria Carmen Redal-Peña, Elena Maria Martinez-Navarro, Manuel Sureda, Francisco Jose Fernandez-Morejon, Francisco J. Garcia-Cases, Ramon Gonzalez Manzano, Antonio Brugarolas

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Assessment of target-mediated uptake with immuno-PET: analysis of a phase I clinical trial with an anti-CD44 antibody

Yvonne W. S. Jauw, Marc C. Huisman, Tapan K. Nayak, Danielle J. Vugts, Randolph Christen, Valerie Meresse Naegelen, Dominik Ruettinger, Florian Heil, Adriaan A. Lammertsma, Henk M. W. Verheul, Otto S. Hoekstra, Guus A. M. S. van Dongen, C. Willemien Menke-van der Houven van Oordt

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Phantom and clinical evaluation of the effect of full Monte Carlo collimator modelling in post-SIRT yttrium-90 Bremsstrahlung SPECT imaging

Charlotte A. Porter, Kevin M. Bradley, Eero T. Hippeläinen, Matthew D. Walker, Daniel R. McGowan

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Renal sympathetic nerve activity after catheter-based renal denervation

Linn C. Dobrowolski, Daan W. Eeftinck Schattenkerk, C. T. Paul Krediet, Peter M. Van Brussel, Liffert Vogt, Frederike J. Bemelman, Jim A. Reekers, Bert-Jan H. Van Den Born, Hein J. Verberne

01.12.2018 | Letter to the Editor | Ausgabe 1/2018 Open Access

It is time to move forward into the era of Theranostics

Hojjat Ahmadzadehfar, Markus Essler

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Biokinetics, dosimetry, and radiation risk in infants after 99mTc-MAG3 scans

J. Soares Machado, J. Tran-Gia, S. Schlögl, A. K. Buck, M. Lassmann

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Feasibility of 15O-water PET studies of auditory system activation during general anesthesia in children

Martin Mamach, Florian Wilke, Martin Durisin, Frank A. Beger, Mareike Finke, Andreas Büchner, Barbara Schultz, Arthur Schultz, Lilli Geworski, Frank M. Bengel, Thomas Lenarz, Anke Lesinski-Schiedat, Georg Berding

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195

Xinyu Chen, Rudolf A. Werner, Constantin Lapa, Naoko Nose, Mitsuru Hirano, Mehrbod S. Javadi, Simon Robinson, Takahiro Higuchi

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Statistical evaluation of test-retest studies in PET brain imaging

Richard Baumgartner, Aniket Joshi, Dai Feng, Francesca Zanderigo, R. Todd Ogden

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

A new SPECT/CT reconstruction algorithm: reliability and accuracy in clinical routine for non-oncologic bone diseases

Olivier Delcroix, Philippe Robin, Maelenn Gouillou, Alexandra Le Duc-Pennec, Zarrin Alavi, Pierre-Yves Le Roux, Ronan Abgral, Pierre-Yves Salaun, David Bourhis, Solène Querellou

01.12.2018 | Preliminary research | Ausgabe 1/2018 Open Access

Feasibility of intraoperative detection of sentinel lymph nodes with 89-zirconium-labelled nanocolloidal albumin PET-CT and a handheld high-energy gamma probe

Derrek A. Heuveling, K. Hakki Karagozoglu, Arthur Van Lingen, Otto S. Hoekstra, Guus A. M. S. Van Dongen, Remco De Bree

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging

Elisabeth Eppard, Ana de la Fuente, Nicole Mohr, Mareli Allmeroth, Rudolf Zentel, Matthias Miederer, Stefanie Pektor, Frank Rösch

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Hyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis

Christian H. Pfob, Matthias Eiber, Peter Luppa, Florian Maurer, Tobias Maurer, Robert Tauber, Calogero D’Alessandria, Benedikt Feuerecker, Klemens Scheidhauer, Armin Ott, Uwe Heemann, Markus Schwaiger, Christoph Schmaderer

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Biokinetic and dosimetric aspects of 64CuCl2 in human prostate cancer: possible theranostic implications

Sergio Righi, Martina Ugolini, Gianluca Bottoni, Matteo Puntoni, Massimiliano Iacozzi, Francesco Paparo, Manlio Cabria, Luca Ceriani, Monica Gambaro, Luca Giovanella, Arnoldo Piccardo

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Imaging Aβ and tau in early stage Alzheimer’s disease with [18F]AV45 and [18F]AV1451

Azadeh Firouzian, Alex Whittington, Graham E. Searle, Ivan Koychev, Giovanna Zamboni, Simon Lovestone, Roger N. Gunn, on behalf of the Deep and Frequent Phenotyping study team

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

I-124 codrituzumab imaging and biodistribution in patients with hepatocellular carcinoma

Jorge A. Carrasquillo, Joseph A. O’Donoghue, Volkan Beylergil, Shutian Ruan, Neeta Pandit-Taskar, Steven M. Larson, Peter M. Smith-Jones, Serge K. Lyashchenko, Norihisa Ohishi, Toshihiko Ohtomo, Ghassan K. Abou-Alfa

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Noninvasive quantitation of rat cerebral blood flow using 99mTc-HMPAO—assessment of input function with dynamic chest planar imaging

Chie Suzuki, Mutsumi Kosugi, Yasuhiro Magata

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Validation of [18F]FLT as a perfusion-independent imaging biomarker of tumour response in EGFR-mutated NSCLC patients undergoing treatment with an EGFR tyrosine kinase inhibitor

R. Iqbal, G. M. Kramer, V. Frings, E. F. Smit, O. S. Hoekstra, R. Boellaard, on behalf of the QuIC-ConCePT Consortium

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Accuracy of tumor segmentation from multi-parametric prostate MRI and 18F-choline PET/CT for focal prostate cancer therapy applications

Morand Piert, Prasad R. Shankar, Jeffrey Montgomery, Lakshmi Priya Kunju, Virginia Rogers, Javed Siddiqui, Thekkelnaycke Rajendiran, Jason Hearn, Arvin George, Xia Shao, Matthew S. Davenport

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Comparison of three-parameter kinetic model analysis to standard Patlak’s analysis in 18F-FDG PET imaging of lung cancer patients

E. Laffon, M. L. Calcagni, G. Galli, A. Giordano, A. Capotosti, R. Marthan, L. Indovina

01.12.2018 | Preliminary research | Ausgabe 1/2018 Open Access

Treatment response assessment with (R)-[11CPAQ PET in the MMTV-PyMT mouse model of breast cancer

T. Tegnebratt, L. Lu, S. Eksborg, A. Chireh, P. Damberg, S. Nikkhou-Aski, T. Foukakis, H. Rundqvist, S. Holmin, R. V. Kuiper, E. Samen

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Using in vivo fluorescence lifetime imaging to detect HER2-positive tumors

Yasaman Ardeshirpour, Dan L. Sackett, Jay R. Knutson, Amir H. Gandjbakhche

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Hallmarks in prostate cancer imaging with Ga68-PSMA-11-PET/CT with reference to detection limits and quantitative properties

Alejandro Sanchez-Crespo, Emma Jussing, Ann-Charlotte Björklund, Katja Pokrovskaja Tamm

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Assessment of glucose metabolism and cellular proliferation in multiple myeloma: a first report on combined 18F-FDG and 18F-FLT PET/CT imaging

C. Sachpekidis, H. Goldschmidt, K. Kopka, A. Kopp-Schneider, A. Dimitrakopoulou-Strauss

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Evaluation of prognostic models developed using standardised image features from different PET automated segmentation methods

Craig Parkinson, Kieran Foley, Philip Whybra, Robert Hills, Ashley Roberts, Chris Marshall, John Staffurth, Emiliano Spezi

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007

Stephanie Robu, Alexander Schmidt, Matthias Eiber, Margret Schottelius, Thomas Günther, Behrooz Hooshyar Yousefi, Markus Schwaiger, Hans-Jürgen Wester

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Correlation of neuropsychological and metabolic changes after epilepsy surgery in patients with left mesial temporal lobe epilepsy with hippocampal sclerosis

Canan Güvenç, Patrick Dupont, Jan Van den Stock, Laura Seynaeve, Kathleen Porke, Eva Dries, Karen Van Bouwel, Johannes van Loon, Tom Theys, Karolien E. Goffin, Wim Van Paesschen

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

External radiation exposure, excretion, and effective half-life in 177Lu-PSMA-targeted therapies

J. Kurth, B. J. Krause, S. M. Schwarzenböck, L. Stegger, M. Schäfers, K. Rahbar

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Structural studies on radiopharmaceutical DOTA-minigastrin analogue (CP04) complexes and their interaction with CCK2 receptor

Piotr F. J. Lipiński, Piotr Garnuszek, Michał Maurin, Raphael Stoll, Nils Metzler-Nolte, Artur Wodyński, Jan Cz. Dobrowolski, Marta K. Dudek, Monika Orzełowska, Renata Mikołajczak

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

On the optimal z-score threshold for SISCOM analysis to localize the ictal onset zone

Liesbeth De Coster, Koen Van Laere, Evy Cleeren, Kristof Baete, Patrick Dupont, Wim Van Paesschen, Karolien E. Goffin

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

[18F]DPA-714 PET imaging shows immunomodulatory effect of intravenous administration of bone marrow stromal cells after transient focal ischemia

Chengbo Tan, Songji Zhao, Kei Higashikawa, Zifeng Wang, Masahito Kawabori, Takeo Abumiya, Naoki Nakayama, Ken Kazumata, Naoyuki Ukon, Hironobu Yasui, Nagara Tamaki, Yuji Kuge, Hideo Shichinohe, Kiyohiro Houkin

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Computer-aided diagnosis for (123I)FP-CIT imaging: impact on clinical reporting

Jonathan Christopher Taylor, Charles Romanowski, Eleanor Lorenz, Christine Lo, Oliver Bandmann, John Fenner

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Assessing the kidney function parameters glomerular filtration rate and effective renal plasma flow with dynamic FDG-PET/MRI in healthy subjects

Barbara K. Geist, Pascal Baltzer, Barbara Fueger, Martina Hamboeck, Thomas Nakuz, Laszlo Papp, Sazan Rasul, Lalith Kumar Shiyam Sundar, Marcus Hacker, Anton Staudenherz

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Monitoring scanner calibration using the image-derived arterial blood SUV in whole-body FDG-PET

Jens Maus, Frank Hofheinz, Ivayla Apostolova, Michael C. Kreissl, Jörg Kotzerke, Jörg van den Hoff

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

Berend van der Wildt, Micha M. M. Wilhelmus, Wissam Beaino, Esther J. M. Kooijman, Robert C. Schuit, John G. J. M. Bol, John J. P. Breve, Ralf Pasternack, Adriaan A. Lammertsma, Albert D. Windhorst, Benjamin Drukarch

01.12.2018 | Original Research | Ausgabe 1/2018 Open Access

Evaluation of hepatic integrin αvβ3 expression in non-alcoholic steatohepatitis (NASH) model mouse by 18F-FPP-RGD2 PET

Takemi Rokugawa, Haruyo Konishi, Miwa Ito, Hitoshi Iimori, Ryohei Nagai, Eku Shimosegawa, Jun Hatazawa, Kohji Abe

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Impact of time-of-flight PET on quantification accuracy and lesion detection in simultaneous 18F-choline PET/MRI for prostate cancer

Urs J. Muehlematter, Hannes W. Nagel, Anton Becker, Julian Mueller, Kerstin N. Vokinger, Felipe de Galiza Barbosa, Edwin E. G. T. ter Voert, Patrick Veit-Haibach, Irene A. Burger

01.12.2018 | Original Research | Ausgabe 1/2018 Open Access

Volume of interest delineation techniques for 18F-FDG PET-CT scans during neoadjuvant extremity soft tissue sarcoma treatment in adults: a feasibility study

Marc G. Stevenson, Lukas B. Been, Harald J. Hoekstra, Albert J. H. Suurmeijer, Ronald Boellaard, Adrienne H. Brouwers

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Detection of neuroinflammation before selective neuronal loss appearance after mild focal ischemia using [18F]DPA-714 imaging

Natsumi Miyajima, Miwa Ito, Takemi Rokugawa, Hitoshi Iimori, Sotaro Momosaki, Shigeki Omachi, Eku Shimosegawa, Jun Hatazawa, Kohji Abe

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Effect of starvation on brain glucose metabolism and 18F-2-fluoro-2-deoxyglucose uptake: an experimental in-vivo and ex-vivo study

Ambra Buschiazzo, Vanessa Cossu, Matteo Bauckneht, Annamaria Orengo, Patrizia Piccioli, Laura Emionite, Giovanna Bianchi, Federica Grillo, Anna Rocchi, Francesco Di Giulio, Francesco Fiz, Lizzia Raffaghello, Flavio Nobili, Silvia Bruno, Giacomo Caviglia, Silvia Ravera, Fabio Benfenati, Michele Piana, Silvia Morbelli, Gianmario Sambuceti, Cecilia Marini

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

The renal blood flow reserve in healthy humans and patients with atherosclerotic renovascular disease measured by positron emission tomography using [15O]H2O

Johanna Päivärinta, Niina Koivuviita, Vesa Oikonen, Hidehiro Iida, Kaisa Liukko, Ilkka Manner, Eliisa Löyttyniemi, Pirjo Nuutila, Kaj Metsärinne

01.12.2018 | Short Communication | Ausgabe 1/2018 Open Access

Simplifying [18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

Colm J. McGinnity, Daniela A. Riaño Barros, William Trigg, David J. Brooks, Rainer Hinz, John S. Duncan, Matthias J. Koepp, Alexander Hammers

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Evaluation of D-isomers of 4-borono-2-18F-fluoro-phenylalanine and O-11C-methyl-tyrosine as brain tumor imaging agents: a comparative PET study with their L-isomers in rat brain glioma

Masakatsu Kanazawa, Shingo Nishiyama, Fumio Hashimoto, Takeharu Kakiuchi, Hideo Tsukada

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

Histamine H3 receptor density is negatively correlated with neural activity related to working memory in humans

Takehito Ito, Yasuyuki Kimura, Chie Seki, Masanori Ichise, Keita Yokokawa, Kazunori Kawamura, Hidehiko Takahashi, Makoto Higuchi, Ming-Rong Zhang, Tetsuya Suhara, Makiko Yamada

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Optimization of temporal sampling for 18F-choline uptake quantification in prostate cancer assessment

Xavier Palard-Novello, Anne-Lise Blin, Florence Le Jeune, Etienne Garin, Pierre-Yves Salaün, Anne Devillers, Giulio Gambarota, Solène Querellou, Patrick Bourguet, Hervé Saint-Jalmes

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

The value of 99mTc-MAA SPECT/CT for lung shunt estimation in 90Y radioembolization: a phantom and patient study

Jonathan D. Allred, Jeremy Niedbala, Justin K. Mikell, Dawn Owen, Kirk A. Frey, Yuni K. Dewaraja

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

PET imaging of 68Ga-NODAGA-RGD, as compared with 18F-fluorodeoxyglucose, in experimental rodent models of engrafted glioblastoma

Sibel Isal, Julien Pierson, Laetitia Imbert, Alexandra Clement, Charlotte Collet, Sophie Pinel, Nicolas Veran, Aurélie Reinhard, Sylvain Poussier, Guillaume Gauchotte, Steeven Frezier, Gilles Karcher, Pierre-Yves Marie, Fatiha Maskali

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Spatial relationship of 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography and magnetic resonance diffusion imaging metrics in cervical cancer

John M. Floberg, Kathryn J. Fowler, Dominique Fuser, Todd A. DeWees, Farrokh Dehdashti, Barry A. Siegel, Richard L. Wahl, Julie K. Schwarz, Perry W. Grigsby

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

18F-fluoromisonidazole predicts evofosfamide uptake in pancreatic tumor model

Milan Grkovski, Louise Fanchon, Naga Vara Kishore Pillarsetty, James Russell, John L. Humm

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model

Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry III, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl, James M. Warwick, the Catalysis Biomarker Consortium

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Impact of external cooling with icepacks on 68Ga-PSMA uptake in salivary glands

Ludwike W. M. van Kalmthout, Marnix G. E. H. Lam, Bart de Keizer, Gerard C. Krijger, Tessa F. T. Ververs, Rememrt de Roos, Arthur J. A. T. Braat

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects

Erica M. Richards, Paolo Zanotti-Fregonara, Masahiro Fujita, Laura Newman, Cristan Farmer, Elizabeth D. Ballard, Rodrigo Machado-Vieira, Peixiong Yuan, Mark J. Niciu, Chul Hyoung Lyoo, Ioline D. Henter, Giacomo Salvadore, Wayne C. Drevets, Hartmuth Kolb, Robert B. Innis, Carlos A. Zarate Jr

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Non-invasive kinetic modelling of PET tracers with radiometabolites using a constrained simultaneous estimation method: evaluation with 11C-SB201745

Hasan Sari, Kjell Erlandsson, Lisbeth Marner, Ian Law, Henrik B.W. Larsson, Kris Thielemans, Sébastien Ourselin, Simon Arridge, David Atkinson, Brian F. Hutton

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models

Patrick L. Donabedian, Susanne Kossatz, John A. Engelbach, Stephen A. Jannetti, Brandon Carney, Robert J. Young, Wolfgang A. Weber, Joel R. Garbow, Thomas Reiner

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

90Y-PET/CT-based dosimetry after selective internal radiation therapy predicts outcome in patients with liver metastases from colorectal cancer

Hugo Levillain, Ivan Duran Derijckere, Gwennaëlle Marin, Thomas Guiot, Michaël Vouche, Nick Reynaert, Alain Hendlisz, Bruno Vanderlinden, Patrick Flamen

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Sensitive and early detection of mitochondrial dysfunction in the liver of NASH model mice by PET imaging with 18F-BCPP-BF

Toshihiro Sakai, Hiroyuki Ohba, Shingo Nishiyama, Takeharu Kakiuchi, Osamu Inoue, Hideo Tsukada

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Visualization of ischemic stroke-related changes on 18F-THK-5351 positron emission tomography

Kuo-Lun Huang, Jung-Lung Hsu, Kun-Ju Lin, Chien-Hung Chang, Yi-Ming Wu, Ting-Yu Chang, Yeu-Jhy Chang, Chi-Hung Liu, Meng-Yang Ho, Shiaw-Pyng Wey, Tzu-Chen Yen, Nobuyuki Okamura, Ing-Tsung Hsiao, Tsong-Hai Lee

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Reproducible quantification of cardiac sympathetic innervation using graphical modeling of carbon-11-meta-hydroxyephedrine kinetics with dynamic PET-CT imaging

Tong Wang, Kai Yi Wu, Robert C. Miner, Jennifer M. Renaud, Rob S. B. Beanlands, Robert A. deKemp

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

18F-FDG and 68Ga-somatostatin analogs PET/CT in patients with Merkel cell carcinoma: a comparison study

Silvia Taralli, Martina Sollini, Michele Milella, Germano Perotti, Angelina Filice, Massimo Menga, Annibale Versari, Vittoria Rufini

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Presurgical localization of infected avascular bone segments in chronic complicated posttraumatic osteomyelitis in the lower extremity using dual-tracer PET/CT

Albert Christersson, Sune Larsson, Jens Sörensen

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

18F-florbetaben whole-body PET/MRI for evaluation of systemic amyloid deposition

Lucia Baratto, Sonya Youngju Park, Negin Hatami, Praveen Gulaka, Shreyas Vasanawala, Thomas Koshy Yohannan, Robert Herfkens, Ronald Witteles, Andrei Iagaru

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

[18F]Fluciclovine PET discrimination between high- and low-grade gliomas

Ephraim E. Parent, Marc Benayoun, Ijeoma Ibeanu, Jeffrey J. Olson, Constantinos G. Hadjipanayis, Daniel J. Brat, Vikram Adhikarla, Jonathon Nye, David M. Schuster, Mark M. Goodman

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: impact of time-of-flight PET on quantification accuracy and lesion detection in simultaneous 18F-choline PET/MRI for prostate cancer

Urs J. Muehlematter, Hannes W. Nagel, Anton Becker, Julian Mueller, Kerstin N. Vokinger, Felipe de Galiza Barbosa, Edwin E. G. T. ter Voert, Patrick Veit-Haibach, Irene A. Burger

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

Jasper van der Aart, Sandeep S. V. Golla, Marieke van der Pluijm, Lothar A. Schwarte, Robert C. Schuit, Pieter J. Klein, Athanasios Metaxas, Albert D. Windhorst, Ronald Boellaard, Adriaan A. Lammertsma, Bart N. M. van Berckel

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Quantitative performance and optimal regularization parameter in block sequential regularized expectation maximization reconstructions in clinical 68Ga-PSMA PET/MR

Edwin E. G. W. ter Voert, Urs J. Muehlematter, Gaspar Delso, Daniele A. Pizzuto, Julian Müller, Hannes W. Nagel, Irene A. Burger

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

Ashwin V. Venkataraman, Nicholas Keat, James F. Myers, Samuel Turton, Inge Mick, Roger N. Gunn, Eugenii A. Rabiner, Jan Passchier, Christine A. Parker, Robin J. Tyacke, David J. Nutt

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Quantification of O-(2-[18F]fluoroethyl)-L-tyrosine kinetics in glioma

Thomas Koopman, Niels Verburg, Robert C. Schuit, Petra J. W. Pouwels, Pieter Wesseling, Albert D. Windhorst, Otto S. Hoekstra, Philip C. de Witt Hamer, Adriaan A. Lammertsma, Ronald Boellaard, Maqsood Yaqub

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Whole tumor kinetics analysis of 18F-fluoromisonidazole dynamic PET scans of non-small cell lung cancer patients, and correlations with perfusion CT blood flow

Daniel R. McGowan, Michael Skwarski, Bartlomiej W. Papiez, Ruth E. Macpherson, Fergus V. Gleeson, Julia A. Schnabel, Geoff S. Higgins, John D. Fenwick

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

[11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis

Per Stenkrona, Granville J. Matheson, Simon Cervenka, Pontus Plavén Sigray, Christer Halldin, Lars Farde

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

Keelara Abiraj, Samer Ursillo, Maria Luisa Tamma, Svetlana N. Rylova, Beatrice Waser, Edwin C. Constable, Melpomeni Fani, Guillaume P. Nicolas, Jean Claude Reubi, Helmut R. Maecke

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Patient-specific image-based bone marrow dosimetry in Lu-177-[DOTA0,Tyr3]-Octreotate and Lu-177-DKFZ-PSMA-617 therapy: investigation of a new hybrid image approach

Astrid Gosewisch, Andreas Delker, Sebastian Tattenberg, Harun Ilhan, Andrei Todica, Julia Brosch, Lena Vomacka, Anika Brunegraf, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein, Guido Böning

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Correlation of the absorbed dose to the blood and DNA damage in leukocytes after internal ex-vivo irradiation of blood samples with Ra-224

Sarah Schumann, Uta Eberlein, Jessica Müller, Harry Scherthan, Michael Lassmann

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester, Johannes Notni

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

A novel partial volume correction method for accurate quantification of [18F] flortaucipir in the hippocampus

Emma E. Wolters, Sandeep S. V. Golla, Tessa Timmers, Rik Ossenkoppele, Chris W. J. van der Weijden, Philip Scheltens, Lothar Schwarte, Robert C. Schuit, Albert D. Windhorst, Frederik Barkhof, Maqsood Yaqub, Adriaan A. Lammertsma, Ronald Boellaard, Bart N. M. van Berckel

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

Stefanie Pektor, Lina Hilscher, Kerstin C. Walzer, Isabelle Miederer, Nicole Bausbacher, Carmen Loquai, Mathias Schreckenberger, Ugur Sahin, Mustafa Diken, Matthias Miederer

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Impact of rifampicin-inhibitable transport on the liver distribution and tissue kinetics of erlotinib assessed with PET imaging in rats

Dorra Amor, Sébastien Goutal, Solène Marie, Fabien Caillé, Martin Bauer, Oliver Langer, Sylvain Auvity, Nicolas Tournier

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Anti PD-1 treatment increases [18F]FDG uptake by cancer cells in a mouse B16F10 melanoma model

Mayu Tomita, Hironobu Yasui, Kei Higashikawa, Kohei Nakajima, Hideo Takakura, Tohru Shiga, Yuji Kuge, Mikako Ogawa

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Multicentre analysis of PET SUV using vendor-neutral software: the Japanese Harmonization Technology (J-Hart) study

Yuji Tsutsui, Hiromitsu Daisaki, Go Akamatsu, Takuro Umeda, Matsuyoshi Ogawa, Hironori Kajiwara, Shigeto Kawase, Minoru Sakurai, Hiroyuki Nishida, Keiichi Magota, Kazuaki Mori, Masayuki Sasaki, J-Hart study group

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

Martina Wirtz, Alexander Schmidt, Margret Schottelius, Stephanie Robu, Thomas Günther, Markus Schwaiger, Hans-Jürgen Wester

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

Clinical evaluation of [123I]FP-CIT SPECT scans on the novel brain-dedicated InSPira HD SPECT system: a head-to-head comparison

Sofie M. Adriaanse, Tim C. de Wit, Mette Stam, Eline Verwer, Kora M. de Bruin, Jan Booij

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Radiomics of the primary tumour as a tool to improve 18F-FDG-PET sensitivity in detecting nodal metastases in endometrial cancer

Elisabetta De Bernardi, Alessandro Buda, Luca Guerra, Debora Vicini, Federica Elisei, Claudio Landoni, Robert Fruscio, Cristina Messa, Cinzia Crivellaro

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate

Christian Brand, Ahmad Sadique, Jacob L. Houghton, Kishore Gangangari, Jose F. Ponte, Jason S. Lewis, Naga Vara Kishore Pillarsetty, Jason A. Konner, Thomas Reiner

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

The kinetics of 18F-FDG in lung cancer: compartmental models and voxel analysis

Erica Silvestri, Valentina Scolozzi, Gaia Rizzo, Luca Indovina, Marco Castellaro, Maria Vittoria Mattoli, Paolo Graziano, Giuseppe Cardillo, Alessandra Bertoldo, Maria Lucia Calcagni

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Dosimetry methods and clinical applications in peptide receptor radionuclide therapy for neuroendocrine tumours: a literature review

Daphne Merel Valerie Huizing, Berlinda Jantina de Wit-van der Veen, Marcel Verheij, Marcellus Petrus Maria Stokkel

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma

Tibor Vag, Katja Steiger, Andreas Rossmann, Ulrich Keller, Aurelia Noske, Peter Herhaus, Johannes Ettl, Markus Niemeyer, Hans-Jürgen Wester, Markus Schwaiger

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Voxel-wise analysis of dynamic 18F-FET PET: a novel approach for non-invasive glioma characterisation

Lena Vomacka, Marcus Unterrainer, Adrien Holzgreve, Erik Mille, Astrid Gosewisch, Julia Brosch, Sibylle Ziegler, Bogdana Suchorska, Friedrich-Wilhelm Kreth, Jörg-Christian Tonn, Peter Bartenstein, Nathalie Lisa Albert, Guido Böning

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Feasibility of biventricular volume and function assessment using first-pass gated 15O-water PET

Fayçal Ben Bouallègue, Denis Mariano-Goulart, Denis Agostini, Alain Manrique

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Brain metabolism and related connectivity in patients with acrophobia treated by virtual reality therapy: an 18F-FDG PET pilot study sensitized by virtual exposure

Antoine Verger, Eric Malbos, Emmanuelle Reynaud, Pierre Mallet, Daniel Mestre, Jean-Marie Pergandi, Stéphanie Khalfa, Eric Guedj

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Which is the proper reference tissue for measuring the change in FDG PET metabolic volume of cardiac sarcoidosis before and after steroid therapy?

Sho Furuya, Osamu Manabe, Hiroshi Ohira, Kenji Hirata, Tadao Aikawa, Masanao Naya, Ichizo Tsujino, Kazuhiro Koyanagawa, Toshihisa Anzai, Noriko Oyama-Manabe, Tohru Shiga

01.12.2018 | Original Research | Ausgabe 1/2018 Open Access

Development and evaluation of a rapid analysis for HEPES determination in 68Ga-radiotracers

Sarah Pfaff, Tina Nehring, Verena Pichler, Jens Cardinale, Markus Mitterhauser, Marcus Hacker, Wolfgang Wadsak

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer

Katharina Lückerath, Liu Wei, Wolfgang P. Fendler, Susan Evans-Axelsson, Andreea D. Stuparu, Roger Slavik, Christine E. Mona, Jeremie Calais, Matthew Rettig, Robert E. Reiter, Ken Herrmann, Caius G. Radu, Johannes Czernin, Matthias Eiber

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Performance evaluation of the next generation solid-state digital photon counting PET/CT system

Jun Zhang, Piotr Maniawski, Michael V. Knopp

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

In vivo confirmation of altered hepatic glucose metabolism in patients with liver fibrosis/cirrhosis by 18F-FDG PET/CT

Niklas Verloh, Ingo Einspieler, Kirsten Utpatel, Karin Menhart, Stefan Brunner, Frank Hofheinz, Jörg van den Hoff, Philipp Wiggermann, Matthias Evert, Christian Stroszczynski, Dirk Hellwig, Jirka Grosse

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

A new methodology to derive 3D kinetic parametric FDG PET images based on a mathematical approach integrating an error model of measurement

Elyse Colard, Sarkis Delcourt, Laetitia Padovani, Sébastien Thureau, Arthur Dumouchel, Pierrick Gouel, Justine Lequesne, Bardia Farman Ara, Pierre Vera, David Taïeb, Isabelle Gardin, Dominique Barbolosi, Sébastien Hapdey

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison

Susanna Jakobson Mo, Jan Axelsson, Lars Jonasson, Anne Larsson, Mattias J. Ögren, Margareta Ögren, Andrea Varrone, Linda Eriksson, David Bäckström, Sara af Bjerkén, Jan Linder, Katrine Riklund

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Mapping heterogeneity in glucose uptake in metastatic melanoma using quantitative 18F-FDG PET/CT analysis

Ellen C. de Heer, Adrienne H. Brouwers, Ronald Boellaard, Wim J. Sluiter, Gilles F. H. Diercks, Geke A. P. Hospers, Elisabeth G. E. de Vries, Mathilde Jalving

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Test-retest reliability and convergent validity of (R)-[11C]PK11195 outcome measures without arterial input function

Pontus Plavén-Sigray, Granville James Matheson, Zsolt Cselényi, Aurelija Jucaite, Lars Farde, Simon Cervenka

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Implementation of patient dosimetry in the clinical practice after targeted radiotherapy using [177Lu-[DOTA0, Tyr3]-octreotate

Lore Santoro, Erick Mora-Ramirez, Dorian Trauchessec, Soufiane Chouaf, Pierre Eustache, Jean-Pierre Pouget, Pierre-Olivier Kotzki, Manuel Bardiès, Emmanuel Deshayes

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Optimization of a dedicated protocol using a small-voxel PSF reconstruction for head-and-neck 18FDG PET/CT imaging in differentiated thyroid cancer

Renaud Ciappuccini, Cédric Desmonts, Idlir Licaj, Cécile Blanc-Fournier, Stéphane Bardet, Nicolas Aide

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

An analysis of SPECT/CT non-visualization of sentinel lymph nodes in renal tumors

Teele Kuusk, Maarten L. Donswijk, Renato A. Valdés Olmos, Roderick E. De Bruijn, Oscar R. Brouwer, Kees Hendricksen, Simon Horenblas, Katarzyna Jóźwiak, Warner Prevoo, Henk G. Van Der Poel, Bas W. G. Van Rhijn, Esther M. Wit, Axel Bex

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

Alternative headphones for patient noise protection and communication in PET-MR studies of the brain

Lutz Tellmann, Hans Herzog, Frank Boers, Christoph Lerche, N. Jon Shah

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Centiloid scaling for quantification of brain amyloid with [18F]flutemetamol using multiple processing methods

Mark R. Battle, Lovena Chedumbarum Pillay, Val J. Lowe, David Knopman, Bradley Kemp, Christopher C. Rowe, Vincent Doré, Victor L. Villemagne, Christopher J. Buckley

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

First in-human radiation dosimetry of the gastrin-releasing peptide (GRP) receptor antagonist 68Ga-NODAGA-MJ9

Silvano Gnesin, Francesco Cicone, Periklis Mitsakis, Axel Van der Gucht, Sébastien Baechler, Raymond Miralbell, Valentina Garibotto, Thomas Zilli, John O. Prior

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Bone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model

Kingsley O. Asiedu, Munira Ferdousi, Phuongnga T. Ton, Stephen S. Adler, Peter L. Choyke, Noriko Sato

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Glucose metabolic brain patterns to discriminate amyotrophic lateral sclerosis from Parkinson plus syndromes

Martijn Devrome, Donatienne Van Weehaeghe, Joke De Vocht, Philip Van Damme, Koen Van Laere, Michel Koole

01.12.2018 | Short communication | Ausgabe 1/2018 Open Access

Cherenkov luminescence imaging is a fast and relevant preclinical tool to assess tumour hypoxia in vivo

Emiko Desvaux, Alan Courteau, Pierre-Simon Bellaye, Mélanie Guillemin, Camille Drouet, Paul Walker, Bertrand Collin, Richard A. Decréau

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Volume-of-interest-based supervised cluster analysis for pseudo-reference region selection in [18F]DPA-714 PET imaging of the rat brain

Igor Fagner Vieira, Dieter Ory, Cindy Casteels, Fernando R. A. Lima, Koen Van Laere, Guy Bormans, Michel Koole

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass

Mahabuba Jahan, Peter Johnström, Ram K. Selvaraju, Marie Svedberg, Maria Sörhede Winzell, Jenny Bernström, Lee Kingston, Magnus Schou, Zhisheng Jia, Stanko Skrtic, Lars Johansson, Olle Korsgren, Lars Farde, Christer Halldin, Olof Eriksson

01.12.2018 | Original research | Ausgabe 1/2018 Open Access

Implications of reconstruction protocol for histo-biological characterisation of breast cancers using FDG-PET radiomics

Nicolas Aide, Thibault Salomon, Cécile Blanc-Fournier, Jean-Michel Grellard, Christelle Levy, Charline Lasnon

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