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Current Pain and Headache Reports
Erschienen in: Current Pain and Headache Reports 7/2013

01.07.2013 | Myofascial Pain (R Gerwin, Section Editor)

Exploring the Central Modulation Hypothesis: Do Ancient Memory Mechanisms Underlie the Pathophysiology of Trigger Points?

verfasst von: Mark J. L. Hocking

Erschienen in: Current Pain and Headache Reports | Ausgabe 7/2013

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Abstract

A myofascial trigger point (TrP) is a point of focal tenderness, associated with a taut band of muscle fibers, that can develop in any skeletal muscle. TrPs are a common source of pain and motor dysfunction in humans and other vertebrates. There is no universally accepted pathophysiology to explain the etiology, symptomatology and treatment of TrPs. This article reviews and extends the author’s previously published hypothesis for the pathophysiology of TrPs, “Trigger Points and Central Modulation—A New Hypothesis.” The author proposes that central nervous system-maintained global changes in α-motoneuron function, resulting from sustained plateau depolarization, rather than a local dysfunction of the motor endplate, underlie the pathogenesis of TrPs.
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Metadaten
Titel
Exploring the Central Modulation Hypothesis: Do Ancient Memory Mechanisms Underlie the Pathophysiology of Trigger Points?
verfasst von
Mark J. L. Hocking
Publikationsdatum
01.07.2013
Verlag
Springer US
Erschienen in
Current Pain and Headache Reports / Ausgabe 7/2013
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-013-0347-6

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