Focus on paediatrics: 2017

Zurück zum Zitat Peters MJ, Argent A, Festa M, Leteurtre S, Piva J, Thompson A, Willson D, Tissieres P, Tucci M, Lacroix J (2017) The intensive care medicine clinical research agenda in paediatrics. Intensive Care Med. https://doi.org/10.1007/s00134-017-4729-9 Peters MJ, Argent A, Festa M, Leteurtre S, Piva J, Thompson A, Willson D, Tissieres P, Tucci M, Lacroix J (2017) The intensive care medicine clinical research agenda in paediatrics. Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-017-4729-9

Zurück zum Zitat Agus MS, Wypij D, Hirshberg EL, Srinivasan V, Faustino EV, Luckett PM, Alexander JL, Asaro LA, Curley MA, Steil GM, Nadkarni VM, Investigators H-PS, the PN (2017) Tight glycemic control in critically ill children. N Engl J Med 376:729–741CrossRefPubMedPubMedCentral Agus MS, Wypij D, Hirshberg EL, Srinivasan V, Faustino EV, Luckett PM, Alexander JL, Asaro LA, Curley MA, Steil GM, Nadkarni VM, Investigators H-PS, the PN (2017) Tight glycemic control in critically ill children. N Engl J Med 376:729–741CrossRefPubMedPubMedCentral

Zurück zum Zitat Yamada T, Shojima N, Hara K, Noma H, Yamauchi T, Kadowaki T (2017) Glycemic control, mortality, secondary infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med. https://doi.org/10.1007/s00134-017-4801-5 Yamada T, Shojima N, Hara K, Noma H, Yamauchi T, Kadowaki T (2017) Glycemic control, mortality, secondary infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-017-4801-5

Zurück zum Zitat Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E Jr, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon N, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A Jr, Weingarten-Abrams J, Weiss SL, Zimmerman JJ, Zuckerberg AL (2017) The American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: executive summary. Pediatr Crit Care Med 18:884–890CrossRefPubMed Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E Jr, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon N, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A Jr, Weingarten-Abrams J, Weiss SL, Zimmerman JJ, Zuckerberg AL (2017) The American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: executive summary. Pediatr Crit Care Med 18:884–890CrossRefPubMed

Zurück zum Zitat Schlapbach LJ, MacLaren G, Festa M, Alexander J, Erickson S, Beca J, Slater A, Schibler A, Pilcher D, Millar J, Straney L, Australian, New Zealand Intensive Care Society Centre for O, Resource E, Australian, New Zealand Intensive Care Society Paediatric Study G (2017) Prediction of pediatric sepsis mortality within 1 h of intensive care admission. Intensive Care Med 43:1085–1096CrossRefPubMed Schlapbach LJ, MacLaren G, Festa M, Alexander J, Erickson S, Beca J, Slater A, Schibler A, Pilcher D, Millar J, Straney L, Australian, New Zealand Intensive Care Society Centre for O, Resource E, Australian, New Zealand Intensive Care Society Paediatric Study G (2017) Prediction of pediatric sepsis mortality within 1 h of intensive care admission. Intensive Care Med 43:1085–1096CrossRefPubMed

Zurück zum Zitat Cvetkovic M, Lutman D, Ramnarayan P, Pathan N, Inwald DP, Peters MJ (2015) Timing of death in children referred for intensive care with severe sepsis: implications for interventional studies. Pediatr Crit Care Med 16:410–417CrossRefPubMed Cvetkovic M, Lutman D, Ramnarayan P, Pathan N, Inwald DP, Peters MJ (2015) Timing of death in children referred for intensive care with severe sepsis: implications for interventional studies. Pediatr Crit Care Med 16:410–417CrossRefPubMed

Zurück zum Zitat Weiss SL, Balamuth F, Hensley J, Fitzgerald JC, Bush J, Nadkarni VM, Thomas NJ, Hall M, Muszynski J (2017) The epidemiology of hospital death following pediatric severe sepsis: when, why, and how children with sepsis die. Pediatr Crit Care Med 18:823–830CrossRefPubMedPubMedCentral Weiss SL, Balamuth F, Hensley J, Fitzgerald JC, Bush J, Nadkarni VM, Thomas NJ, Hall M, Muszynski J (2017) The epidemiology of hospital death following pediatric severe sepsis: when, why, and how children with sepsis die. Pediatr Crit Care Med 18:823–830CrossRefPubMedPubMedCentral

Zurück zum Zitat Schlapbach LJ, Straney L, Bellomo R, MacLaren G, Pilcher D (2017) Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Med. https://doi.org/10.1007/s00134-017-5021-8 CrossRefPubMedPubMedCentral Schlapbach LJ, Straney L, Bellomo R, MacLaren G, Pilcher D (2017) Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit. Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-017-5021-8 CrossRefPubMedPubMedCentral

Zurück zum Zitat Matics TJ, Sanchez-Pinto LN (2017) Adaptation and validation of a pediatric sequential organ failure assessment score and evaluation of the sepsis-3 definitions in critically ill children. JAMA Pediatr 171:e172352CrossRefPubMed Matics TJ, Sanchez-Pinto LN (2017) Adaptation and validation of a pediatric sequential organ failure assessment score and evaluation of the sepsis-3 definitions in critically ill children. JAMA Pediatr 171:e172352CrossRefPubMed

Zurück zum Zitat Ray S, Rogers L, Noren DP, Dhar R, Nadel S, Peters MJ, Inwald DP (2017) Risk of over-diagnosis of hypotension in children: a comparative analysis of over 50,000 blood pressure measurements. Intensive Care Med 43:1540–1541CrossRefPubMed Ray S, Rogers L, Noren DP, Dhar R, Nadel S, Peters MJ, Inwald DP (2017) Risk of over-diagnosis of hypotension in children: a comparative analysis of over 50,000 blood pressure measurements. Intensive Care Med 43:1540–1541CrossRefPubMed

Zurück zum Zitat James C, Millar J, Horton S, Brizard C, Molesworth C, Butt W (2016) Nitric oxide administration during paediatric cardiopulmonary bypass: a randomised controlled trial. Intensive Care Med 42:1744–1752CrossRefPubMed James C, Millar J, Horton S, Brizard C, Molesworth C, Butt W (2016) Nitric oxide administration during paediatric cardiopulmonary bypass: a randomised controlled trial. Intensive Care Med 42:1744–1752CrossRefPubMed

Zurück zum Zitat Kneyber MCJ, de Luca D, Calderini E, Jarreau PH, Javouhey E, Lopez-Herce J, Hammer J, Macrae D, Markhorst DG, Medina A, Pons-Odena M, Racca F, Wolf G, Biban P, Brierley J, Rimensberger PC, Section Respiratory Failure of the European Society for P, Neonatal Intensive C (2017) Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC). Intensive Care Med. https://doi.org/10.1007/s00134-017-4920-z Kneyber MCJ, de Luca D, Calderini E, Jarreau PH, Javouhey E, Lopez-Herce J, Hammer J, Macrae D, Markhorst DG, Medina A, Pons-Odena M, Racca F, Wolf G, Biban P, Brierley J, Rimensberger PC, Section Respiratory Failure of the European Society for P, Neonatal Intensive C (2017) Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC). Intensive Care Med. https://​doi.​org/​10.​1007/​s00134-017-4920-z

Zurück zum Zitat Ray S, Rogers L, Raman S, Peters MJ, Oxy Pi (2017) Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO2 data. Intensive Care Med 43:146–147CrossRefPubMed Ray S, Rogers L, Raman S, Peters MJ, Oxy Pi (2017) Liberal oxygenation in paediatric intensive care: retrospective analysis of high-resolution SpO₂ data. Intensive Care Med 43:146–147CrossRefPubMed

Zurück zum Zitat Milesi C, Essouri S, Pouyau R, Liet JM, Afanetti M, Portefaix A, Baleine J, Durand S, Combes C, Douillard A, Cambonie G, Groupe Francophone de Reanimation et d’Urgences P (2017) High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study). Intensive Care Med 43:209–216CrossRefPubMed Milesi C, Essouri S, Pouyau R, Liet JM, Afanetti M, Portefaix A, Baleine J, Durand S, Combes C, Douillard A, Cambonie G, Groupe Francophone de Reanimation et d’Urgences P (2017) High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study). Intensive Care Med 43:209–216CrossRefPubMed

Zurück zum Zitat Moreira A, Sapru A, Rimensberger PC (2016) What’s new about circulating biomarkers in pediatric acute lung disease. Intensive Care Med 42:803–805CrossRefPubMedPubMedCentral Moreira A, Sapru A, Rimensberger PC (2016) What’s new about circulating biomarkers in pediatric acute lung disease. Intensive Care Med 42:803–805CrossRefPubMedPubMedCentral

Zurück zum Zitat Harris J, Ramelet AS, van Dijk M, Pokorna P, Wielenga J, Tume L, Tibboel D, Ista E (2016) Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals. Intensive Care Med 42:972–986CrossRefPubMedPubMedCentral Harris J, Ramelet AS, van Dijk M, Pokorna P, Wielenga J, Tume L, Tibboel D, Ista E (2016) Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals. Intensive Care Med 42:972–986CrossRefPubMedPubMedCentral

Zurück zum Zitat Vet NJ, de Wildt SN, Verlaat CW, Knibbe CA, Mooij MG, van Woensel JB, van Rosmalen J, Tibboel D, de Hoog M (2016) A randomized controlled trial of daily sedation interruption in critically ill children. Intensive Care Med 42:233–244CrossRefPubMed Vet NJ, de Wildt SN, Verlaat CW, Knibbe CA, Mooij MG, van Woensel JB, van Rosmalen J, Tibboel D, de Hoog M (2016) A randomized controlled trial of daily sedation interruption in critically ill children. Intensive Care Med 42:233–244CrossRefPubMed

Zurück zum Zitat Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM, Investigators TT (2017) Therapeutic hypothermia after in-hospital cardiac arrest in children. N Engl J Med 376:318–329CrossRefPubMedPubMedCentral Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM, Investigators TT (2017) Therapeutic hypothermia after in-hospital cardiac arrest in children. N Engl J Med 376:318–329CrossRefPubMedPubMedCentral

Zurück zum Zitat van Zellem L, Buysse C, Madderom M, Legerstee JS, Aarsen F, Tibboel D, Utens EM (2015) Long-term neuropsychological outcomes in children and adolescents after cardiac arrest. Intensive Care Med 41:1057–1066CrossRefPubMedPubMedCentral van Zellem L, Buysse C, Madderom M, Legerstee JS, Aarsen F, Tibboel D, Utens EM (2015) Long-term neuropsychological outcomes in children and adolescents after cardiac arrest. Intensive Care Med 41:1057–1066CrossRefPubMedPubMedCentral

Zurück zum Zitat Verstraete S, Vanhorebeek I, Covaci A, Guiza F, Malarvannan G, Jorens PG, Van den Berghe G (2016) Circulating phthalates during critical illness in children are associated with long-term attention deficit: a study of a development and a validation cohort. Intensive Care Med 42:379–392CrossRefPubMed Verstraete S, Vanhorebeek I, Covaci A, Guiza F, Malarvannan G, Jorens PG, Van den Berghe G (2016) Circulating phthalates during critical illness in children are associated with long-term attention deficit: a study of a development and a validation cohort. Intensive Care Med 42:379–392CrossRefPubMed