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Zeitschrift

Journal of Hematology & Oncology

Journal of Hematology & Oncology 1/2013

Ausgabe 1/2013

Inhaltsverzeichnis ( 94 Artikel )

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells

Jie Zou, Peng Li, Fei Lu, Na Liu, Jianjian Dai, Jingjing Ye, Xun Qu, Xiulian Sun, Daoxin Ma, Jino Park, Chunyan Ji

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Comparative efficacy of tandem autologous versus autologous followed by allogeneic hematopoietic cell transplantation in patients with newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials

Mohamed A Kharfan-Dabaja, Mehdi Hamadani, Tea Reljic, Taiga Nishihori, William Bensinger, Benjamin Djulbegovic, Ambuj Kumar

01.12.2013 | Review | Ausgabe 1/2013 Open Access

A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

James D Mellor, Michael P Brown, Helen R Irving, John R Zalcberg, Alexander Dobrovic

01.12.2013 | Research | Ausgabe 1/2013 Open Access

TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity

Benedicte Stavik, Mari Tinholt, Marit Sletten, Grethe Skretting, Per Morten Sandset, Nina Iversen

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

DNA repair gene variants are associated with an increased risk of myelodysplastic syndromes in a Czech population

Monika Belickova, Michaela Dostalova Merkerova, Eliska Stara, Jitka Vesela, Dana Sponerova, Dana Mikulenkova, Radim Brdicka, Radana Neuwirtova, Anna Jonasova, Jaroslav Cermak

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Intensity modulated radiotherapy for sinonasal malignancies with a focus on optic pathway preservation

Alexander Chi, Nam P Nguyen, William Tse, Gill Sobremonte, Patrick Concannon, Angela Zhu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission

Sandra Christoph, Jennifer Schlegel, Francesca Alvarez-Calderon, Yong-Mi Kim, Luis N Brandao, Deborah DeRyckere, Douglas K Graham

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo

Kejian Shi, Qian Jiang, Zhushi Li, Lei Shan, Feng Li, JiaJia An, Yang Yang, Caimin Xu

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases

Xin He, Zhigang Chen, Yangyan Jiang, Xi Qiu, Xiaoying Zhao

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Diverse functions of miR-125 family in different cell contexts

Yu-Meng Sun, Kang-Yu Lin, Yue-Qin Chen

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

Selenium and sulindac are synergistic to inhibit intestinal tumorigenesis in Apc/p21 mice

Xiuli Bi, Nicole Pohl, Huali Dong, Wancai Yang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Busulfan plus fludarabine as a myeloablative conditioning regimen compared with busulfan plus cyclophosphamide for acute myeloid leukemia in first complete remission undergoing allogeneic hematopoietic stem cell transplantation: a prospective and multicenter study

Hui Liu, Xiao Zhai, Zhaoyang Song, Jing Sun, Yang Xiao, Danian Nie, Yu Zhang, Fen Huang, Hongsheng Zhou, Zhiping Fan, Sanfang Tu, Yonghua Li, Xutao Guo, Guopan Yu, Qifa Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Monitoring of minimal residual disease (MRD) is useful to predict prognosis of adult patients with Ph-negative ALL: results of a prospective study (ALL MRD2002 Study)

Koji Nagafuji, Toshihiro Miyamoto, Tetsuya Eto, Tomohiko Kamimura, Shuichi Taniguchi, Takashi Okamura, Eiichi Ohtsuka, Takashi Yoshida, Masakazu Higuchi, Goichi Yoshimoto, Tomoaki Fujisaki, Yasunobu Abe, Yasushi Takamatsu, Shouhei Yokota, Koichi Akashi, Mine Harada

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Epigenetic inactivation of the MIR129-2 in hematological malignancies

Kwan-Yeung Wong, Rita Lok-Hay Yim, Yok-Lam Kwong, Chung-Ying Leung, Pak-Kwan Hui, Florence Cheung, Raymond Liang, Dong-Yan Jin, Chor-Sang Chim

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease

Ted Wun, Denis Soulieres, Andrew L Frelinger, Lakshmanan Krishnamurti, Enrico M Novelli, Abdullah Kutlar, Kenneth I Ataga, Charles L Knupp, Lillian E McMahon, John J Strouse, Chunmei Zhou, Lori E Heath, Chuke E Nwachuku, Joseph A Jakubowski, Jeffrey S Riesmeyer, Kenneth J Winters

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Validation of the M. D. Anderson Symptom Inventory multiple myeloma module

Desiree Jones, Elisabeth G Vichaya, Xin Shelley Wang, Loretta A Williams, Nina D Shah, Sheeba K Thomas, Valen E Johnson, Richard E Champlin, Charles S Cleeland, Tito R Mendoza

01.12.2013 | Research | Ausgabe 1/2013 Open Access

SNS-032 inhibits mTORC1/mTORC2 activity in acute myeloid leukemia cells and has synergistic activity with perifosine against Akt

Haitao Meng, Yingming Jin, Hui Liu, Liangshun You, Chunmei Yang, Xue Yang, Wenbin Qian

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Xinyuan Li, Pu Fang, Jietang Mai, Eric T Choi, Hong Wang, Xiao-feng Yang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice

Ningfei An, Andrew S Kraft, Yubin Kang

01.12.2013 | Reviewer acknowledgement | Ausgabe 1/2013 Open Access

Journal of Hematology & Oncology reviewer acknowledgement 2012

Delong Liu

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Targeting p53 by small molecules in hematological malignancies

Manujendra N Saha, Lugui Qiu, Hong Chang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia

Maoxiang Qian, Wen Jin, Xuehua Zhu, Xiaohong Jia, Xianwen Yang, Yanzhi Du, Kankan Wang, Ji Zhang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

Houda Alachkar, Ramasamy Santhanam, Jason G Harb, David M Lucas, Joshua J Oaks, Christopher J Hickey, Li Pan, A Douglas Kinghorn, Michael A Caligiuri, Danilo Perrotti, John C Byrd, Ramiro Garzon, Michael R Grever, Guido Marcucci

01.12.2013 | Commentary | Ausgabe 1/2013 Open Access

Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium

Yiying Wang, Yue Wang, Jie Li, Janiel Cragun, Kenneth Hatch, Setsuko K Chambers, Wenxin Zheng

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

Presence of alternative lengthening of telomeres associated circular extrachromosome telomere repeats in primary leukemia cells of chronic myeloid leukemia

Oumar Samassekou, Abba Malina, Josée Hébert, Ju Yan

01.12.2013 | Review | Ausgabe 1/2013 Open Access

MEK and the inhibitors: from bench to bedside

Akintunde Akinleye, Muhammad Furqan, Nikhil Mukhi, Pavan Ravella, Delong Liu

01.12.2013 | Letter to the Editor | Ausgabe 1/2013 Open Access

The serum levels of the cytokines involved in the Th17 and Th1 cell commitment are increased in individuals with borderline thrombocytopenia

Andreia Maria Camargos Rocha, Cláudia Souza, Gifone Aguiar Rocha, Fabrício Freire de Melo, Nelma Cristina Diogo Clementino, Marília Campos Abreu Marino, Dulciene Maria Magalhães Queiroz

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

Azacitidine might be beneficial in a subgroup of older AML patients compared to intensive chemotherapy: a single centre retrospective study of 227 consecutive patients

Lieke H van der Helm, Ellen RM Scheepers, Nic JGM Veeger, Simon MGJ Daenen, André B Mulder, Eva van den Berg, Edo Vellenga, Gerwin Huls

01.12.2013 | Review | Ausgabe 1/2013 Open Access

B-Raf and the inhibitors: from bench to bedside

Tiangui Huang, Michael Karsy, Jian Zhuge, Minghao Zhong, Delong Liu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Development and characterization of a high-throughput in vitro cord formation model insensitive to VEGF inhibition

Beverly L Falcon, Belinda O’Clair, Don McClure, Glenn F Evans, Julie Stewart, Michelle L Swearingen, Yuefeng Chen, Kevin Allard, Linda N Lee, Kuldeep Neote, Dyke P McEwen, Mark T Uhlik, Sudhakar Chintharlapalli

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

Azacitidine in patients with WHO-defined AML – Results of 155 patients from the Austrian Azacitidine Registry of the AGMT-Study Group

Lisa Pleyer, Reinhard Stauder, Sonja Burgstaller, Martin Schreder, Christoph Tinchon, Michael Pfeilstocker, Susanne Steinkirchner, Thomas Melchardt, Martina Mitrovic, Michael Girschikofsky, Alois Lang, Peter Krippl, Thamer Sliwa, Alexander Egle, Werner Linkesch, Daniela Voskova, Hubert Angermann, Richard Greil

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen

Yan Zhuang, Xiang Wang, Hong T Nguyen, Ying Zhuo, Xinpeng Cui, Claire Fewell, Erik K Flemington, Bin Shan

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Chimeric antigen receptor containing ICOS signaling domain mediates specific and efficient antitumor effect of T cells against EGFRvIII expressing glioma

Chan-Juan Shen, Yu-Xiu Yang, Ethan Q Han, Na Cao, Yun-Fei Wang, Yi Wang, Ying-Ying Zhao, Li-Ming Zhao, Jian Cui, Puja Gupta, Albert J Wong, Shuang-Yin Han

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Activated N-Ras signaling regulates arterial-venous specification in zebrafish

Chun-Guang Ren, Lei Wang, Xiao-E Jia, Yi-Jie Liu, Zhi-Wei Dong, Yi Jin, Yi Chen, Min Deng, Yong Zhou, Yi Zhou, Rui-Bao Ren, Wei-Jun Pan, Ting-Xi Liu

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Novel agents for chronic lymphocytic leukemia

Mei Wu, Akintunde Akinleye, Xiongpeng Zhu

01.12.2013 | Case report | Ausgabe 1/2013 Open Access

Rapid induction of complete molecular remission by sequential therapy with LDAC and sorafenib in FLT3-ITD-positive patients unfit for intensive treatment: two cases and review of the literature

Denise Wolleschak, Enrico Schalk, Christian Krogel, Tina M Schnoeder, Helga Luehr, Kathleen Jentsch-Ullrich, Thomas Fischer, Florian H Heidel

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Long non-coding RNA: a new player in cancer

Hua Zhang, Zhenhua Chen, Xinxin Wang, Zunnan Huang, Zhiwei He, Yueqin Chen

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology

Katerina Pilatova, Kristina Greplova, Regina Demlova, Beatrix Bencsikova, Giannoula Lakka Klement, Lenka Zdrazilova-Dubska

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Targeted therapy for HER2 positive breast cancer

Jason A Incorvati, Shilpan Shah, Ying Mu, Janice Lu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A multicenter, open-label, phase 2 study of lenalidomide plus low-dose dexamethasone in Chinese patients with relapsed/refractory multiple myeloma: the MM-021 trial

Jian Hou, Xin Du, Jie Jin, Zhen Cai, Fangping Chen, Dao-bin Zhou, Li Yu, Xiaoyan Ke, Xiao Li, Depei Wu, Fanyi Meng, Huisheng Ai, Jingshan Zhang, Honeylet Wortman-Vayn, Nianhang Chen, Jay Mei, Jianmin Wang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Chimeric antigen receptor-engineered T cells for cancer immunotherapy: progress and challenges

Ethan Q Han, Xiu-ling Li, Chun-rong Wang, Tian-fang Li, Shuang-yin Han

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Signal transduction inhibitors in treatment of myelodysplastic syndromes

Lohith Bachegowda, Oleg Gligich, Ionnis Mantzaris, Carolina Schinke, Dale Wyville, Tatiana Carrillo, Ira Braunschweig, Ulrich Steidl, Amit Verma

01.12.2013 | Rapid communication | Ausgabe 1/2013 Open Access

A phase I study of ridaforolimus in adult Chinese patients with advanced solid tumors

Lian Liu, Wen Zhang, Wenhua Li, Fangfang Lv, Zuguang Xia, Sheng Zhang, Wen Liu, Anthe S Zandvliet, Sylvia Waajen, Li Xin Zhang, Li Yan, Jin Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Induction of acquired drug resistance in endothelial cells and its involvement in anticancer therapy

Limin Huang, Christelle Perrault, Jennifer Coelho-Martins, Chaoquan Hu, Charlène Dulong, Mariana Varna, Jielin Liu, Jian Jin, Claudine Soria, Lionel Cazin, Anne Janin, Hong Li, Rémi Varin, He Lu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

A phase II study of sorafenib (BAY 43–9006) in recurrent diffuse large B cell lymphoma: an eastern cooperative oncology group study (E1404)

Daniel R Greenwald, Hailun Li, Selina M Luger, Ronald S Go, David King, Taral Patel, Randy D Gascoyne, Jill Kolesar, Brad S Kahl, Sandra Horning

01.12.2013 | Research | Ausgabe 1/2013 Open Access

L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer

Dong-liang Chen, Zhao-lei Zeng, Jing Yang, Chao Ren, De-shen Wang, Wen-jing Wu, Rui-hua Xu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Protein biomarkers distinguish between high- and low-risk pediatric acute lymphoblastic leukemia in a tissue specific manner

Maria Braoudaki, George I Lambrou, Konstantinos Vougas, Kalliopi Karamolegou, George T Tsangaris, Fotini Tzortzatou-Stathopoulou

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Novel agents and biomarkers for acute lymphoid leukemia

Yanmin Zhao, He Huang, Guoqing Wei

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma

Li Hua Dong, Shu Cheng, Zhong Zheng, Li Wang, Yang Shen, Zhi Xiang Shen, Sai Juan Chen, Wei Li Zhao

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy

Dushyant V Sahani, Tao Jiang, Koichi Hayano, Dan G Duda, Onofrio A Catalano, Marek Ancukiewicz, Rakesh K Jain, Andrew X Zhu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Early stage follicular lymphoma: what is the clinical impact of the first-line treatment strategy?

Anne-Sophie AS Michallet, Laure L Lebras, Deborah D Bauwens, Fadhela F Bouafia-Sauvy, Françoise F Berger, Christelle C Tychyj-Pinel, Anne A D’Hombres, Gilles G Salles, Bertrand B Coiffier

01.12.2013 | Rapid communication | Ausgabe 1/2013 Open Access

A prospective phase II study of L-asparaginase- CHOP plus radiation in newly diagnosed extranodal NK/T-cell lymphoma, nasal type

Ningjing Lin, Yuqin Song, Wen Zheng, Meifeng Tu, Yan Xie, Xiaopei Wang, Lingyan Ping, Zhitao Ying, Chen Zhang, Lijuan Deng, Weiping Liu, Jun Zhu

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Immunomodulation therapy with lenalidomide in follicular, transformed and diffuse large B cell lymphoma: current data on safety and efficacy

Madhav Desai, Kate J Newberry, Jorge Romaguera, Liang Zhang, Zhishuo Ou, Michael Wang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Biomarkers for determining the prognosis in chronic myelogenous leukemia

Kendra Sweet, Ling Zhang, Javier Pinilla-Ibarz

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Immunoglobulin E induces VEGF production in mast cells and potentiates their pro-tumorigenic actions through a Fyn kinase-dependent mechanism

Guillermina Yanek Jiménez-Andrade, Alfredo Ibarra-Sánchez, Diana González, Mónica Lamas, Claudia González-Espinosa

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Epigenetic changes: a common theme in acute myelogenous leukemogenesis

Soraya E Gutierrez, Francisco A Romero-Oliva

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Ibrutinib and novel BTK inhibitors in clinical development

Akintunde Akinleye, Yamei Chen, Nikhil Mukhi, Yongping Song, Delong Liu

01.12.2013 | Letter to the Editor | Ausgabe 1/2013 Open Access

Enhanced levels of asymmetric dimethylarginine in a serum of middle age patients with myelodysplastic syndrome

Jana Štikarová, Jiří Suttnar, Kristýna Pimková, Leona Chrastinová-Mášová, Jaroslav Čermák, Jan E Dyr

01.12.2013 | Research | Ausgabe 1/2013 Open Access

High rate of spontaneous inhibitor clearance during the long term observation study of a single cohort of 524 haemophilia A patients not undergoing immunotolerance

Giuseppe Tagariello, Alfonso Iorio, Davide Matino, Donata Belvini, Roberta Salviato, Roberto Sartori, Paolo Radossi

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Inosine Triphosphate Pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defects

Mazin A Zamzami, John A Duley, Gareth R Price, Deon J Venter, John W Yarham, Robert W Taylor, Laurence P Catley, Timothy HJ Florin, Anthony M Marinaki, Francis Bowling

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models

Michela Capello, Paola Cappello, Federica Caterina Linty, Roberto Chiarle, Isabella Sperduti, Anna Novarino, Paola Salacone, Giorgia Mandili, Alessio Naccarati, Carlotta Sacerdote, Stefania Beghelli, Samantha Bersani, Stefano Barbi, Claudio Bassi, Aldo Scarpa, Paola Nisticò, Mirella Giovarelli, Paolo Vineis, Michele Milella, Francesco Novelli

01.12.2013 | Case report | Ausgabe 1/2013 Open Access

Long-term complete remission with belinostat in a patient with chemotherapy refractory peripheral t-cell lymphoma

Peter Reimer, Shanta Chawla

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation

Qi Shen, Sichu Liu, Yu Chen, Lijian Yang, Shaohua Chen, Xiuli Wu, Bo Li, Yuhong Lu, Kanger Zhu, Yangqiu Li

01.12.2013 | Letter to the Editor | Ausgabe 1/2013 Open Access

Leukemic transformation driven by an ASXL1 mutation after a JAK2V617F-positive primary myelofibrosis: clonal evolution and hierarchy revealed by next-generation sequencing

Francisca Ferrer-Marín, Beatriz Bellosillo, Luz Martínez-Avilés, Gloria Soler, Pablo Carbonell, Ginés Luengo-Gil, Eva Caparrós, José M Torregrosa, Carlos Besses, Vicente Vicente

01.12.2013 | Research | Ausgabe 1/2013 Open Access

PAX8: a sensitive and specific marker to identify cancer cells of ovarian origin for patients prior to neoadjuvant chemotherapy

Yue Wang, Yiying Wang, Jie Li, Zeng Yuan, Bingbing Yuan, Tingguo Zhang, Janiel M Cragun, Beihua Kong, Wenxin Zheng

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Fibroblast growth factor-2 (FGF2) and syndecan-1 (SDC1) are potential biomarkers for putative circulating CD15+/CD30+ cells in poor outcome Hodgkin lymphoma patients

Rajendra Gharbaran, Andre Goy, Takemi Tanaka, Jongwhan Park, Chris Kim, Nafis Hasan, Swathi Vemulapalli, Sreeja Sarojini, Madalina Tuluc, Kip Nalley, Pritish Bhattacharyya, Andrew Pecora, K Stephen Suh

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Perioperative therapy for locally advanced gastroesophageal cancer: current controversies and consensus of care

Amikar Sehdev, Daniel VT Catenacci

01.12.2013 | Review | Ausgabe 1/2013 Open Access

An evolving new paradigm: endothelial cells – conditional innate immune cells

Jietang Mai, Anthony Virtue, Jerry Shen, Hong Wang, Xiao-Feng Yang

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Differential responses to genotoxic agents between induced pluripotent stem cells and tumor cell lines

Yinghua Lu, Dazhong Xu, Jing Zhou, Yupo Ma, Yongping Jiang, Wenxian Zeng, Wei Dai

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Population level survival of patients with chronic myelocytic leukemia in Germany compared to the US in the early 21st century

Dianne Pulte, Benjamin Barnes, Lina Jansen, Nora Eisemann, Katharina Emrich, Adam Gondos, Stefan Hentschel, Bernd Holleczek, Klaus Kraywinkel, Hermann Brenner, the GEKID Cancer Survival Working Group

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Stem cell factor SALL4, a potential prognostic marker for myelodysplastic syndromes

Fei Wang, Ye Guo, Qian Chen, Zhuo Yang, Ning Ning, Yujuan Zhang, Yonggang Xu, Xiaodong Xu, Chunrong Tong, Li Chai, Wei Cui

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Erythropoietin is a JAK2 and ERK1/2 effector that can promote renal tumor cell proliferation under hypoxic conditions

Makito Miyake, Steve Goodison, Adrienne Lawton, Ge Zhang, Evan Gomes-Giacoia, Charles J Rosser

01.12.2013 | Research | Ausgabe 1/2013 Open Access

G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses

Mark P Rubinstein, Mohamed L Salem, Andrew L Doedens, Caitlin J Moore, Cody Chiuzan, Guillermo L Rivell, David J Cole, Ananda W Goldrath

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Clinical significance of cytogenetic aberrations in bone marrow of patients with diffuse large B-cell lymphoma: prognostic significance and relevance to histologic involvement

Seon Young Kim, Hyo Jung Kim, Hye Jin Kang, Jin Seok Kim, Hyeon Seok Eom, Tae Min Kim, Sung-Soo Yoon, Cheolwon Suh, Dong Soon Lee, Korean Society of Hematology Lymphoma Working Party

01.12.2013 | Research | Ausgabe 1/2013 Open Access

IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells

Xiaoli Chen, Junke Zheng, Yizhou Zou, Chun Song, Xuemei Hu, Cheng Cheng Zhang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies

Li Shi, Shaohua Chen, Lijian Yang, Yangqiu Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Inhibition of Hedgehog signaling sensitizes NSCLC cells to standard therapies through modulation of EMT-regulating miRNAs

Aamir Ahmad, Ma’in Y Maitah, Kevin R Ginnebaugh, Yiwei Li, Bin Bao, Shirish M Gadgeel, Fazlul H Sarkar

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity

Laura Quotti Tubi, Carmela Gurrieri, Alessandra Brancalion, Laura Bonaldi, Roberta Bertorelle, Sabrina Manni, Laura Pavan, Federica Lessi, Renato Zambello, Livio Trentin, Fausto Adami, Maria Ruzzene, Lorenzo A Pinna, Gianpietro Semenzato, Francesco Piazza

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Optimizing management of ruxolitinib in patients with myelofibrosis: the need for individualized dosing

Ruben A Mesa, Jorge Cortes

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application

Federico Pozzo, Michele Dal Bo, Nadia Peragine, Riccardo Bomben, Antonella Zucchetto, Francesca Maria Rossi, Massimo Degan, Davide Rossi, Annalisa Chiarenza, Alberto Grossi, Francesco Di Raimondo, Francesco Zaja, Gabriele Pozzato, Paola Secchiero, Gianluca Gaidano, Giovanni Del Poeta, Giorgio Zauli, Robin Foà, Anna Guarini, Valter Gattei

01.12.2013 | Letter to the Editor | Ausgabe 1/2013 Open Access

STAT3 mutations are frequent in T-cell large granular lymphocytic leukemia with pure red cell aplasia

Zhi-Yuan Qiu, Lei Fan, Li Wang, Chun Qiao, Yu-Jie Wu, Jian-Feng Zhou, Wei Xu, Jian-Yong Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Enhancing bone marrow regeneration by SALL4 protein

Wenbin Liao, Jerell R Aguila, Yixin Yao, Jianchang Yang, Gary Zieve, Yongping Jiang, Cecilia Avila, Lisa Senzel, Raymond Lai, Dazhong Xu, Wei Dai, Yupo Ma

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

Akintunde Akinleye, Parthu Avvaru, Muhammad Furqan, Yongping Song, Delong Liu

01.12.2013 | Short report | Ausgabe 1/2013 Open Access

miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells

Ana Costa, Joana Afonso, Catarina Osório, Ana L Gomes, Francisco Caiado, Joana Valente, Sandra I Aguiar, Francisco Pinto, Mário Ramirez, Sérgio Dias

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Extranodal natural killer/T-cell lymphoma involving the gastrointestinal tract: analysis of clinical features and outcomes from the Asia Lymphoma study group

Seok Jin Kim, Hyun Ae Jung, Shih-Sung Chuang, Huangming Hong, Cheng-Cheng Guo, Junning Cao, Xiao-Nan Hong, Ritsuro Suzuki, Hye Jin Kang, Jong Ho Won, Wee-Joo Chng, Yok-Lam Kwong, Cheolwon Suh, Yu-Qin Song, Jun Zhu, Kevin Tay, Soon Thye Lim, Junji Suzumiya, Tong-Yu Lin, Won Seog Kim

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Adjuvant zoledronic acid therapy for patients with early stage breast cancer: an updated systematic review and meta-analysis

Mingfeng He, Weidong Fan, Xianquan Zhang

01.12.2013 | Review | Ausgabe 1/2013 Open Access

STAT inhibitors for cancer therapy

Muhammad Furqan, Akintunde Akinleye, Nikhil Mukhi, Varun Mittal, Yamei Chen, Delong Liu

01.12.2013 | Review | Ausgabe 1/2013 Open Access

Fact or fiction - identifying the elusive multiple myeloma stem cell

Joshua Kellner, Bei Liu, Yubin Kang, Zihai Li

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma

Beatriz Somovilla-Crespo, Manuel Alfonso-Pérez, Carlos Cuesta-Mateos, Cristina Carballo-de Dios, Amada E Beltrán, Fernando Terrón, Juan J Pérez-Villar, Carlos Gamallo-Amat, Gema Pérez-Chacón, Elena Fernández-Ruiz, Juan M Zapata, Cecilia Muñoz-Calleja

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor

Xiaoling Du, Jilong Yang, Antti Ylipää, Ze Zhu

01.12.2013 | Research | Ausgabe 1/2013 Open Access

Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines

Cornel Joseph Phillip, Shadia Zaman, Shujun Shentu, Kumudha Balakrishnan, Jiexin Zhang, Veera Baladandayuthapani, Pietro Taverna, Sanjeev Redkar, Michael Wang, Christine Marie Stellrecht, Varsha Gandhi

01.12.2013 | Review | Ausgabe 1/2013 Open Access

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