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Zeitschrift

Journal of Hematology & Oncology

Journal of Hematology & Oncology 1/2014

Ausgabe 1/2014

Inhaltsverzeichnis ( 95 Artikel )

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors

L Rhoda Molife, Li Yan, Joanna Vitfell-Rasmussen, Adriane M Zernhelt, Daniel M Sullivan, Philippe A Cassier, Eric Chen, Andrea Biondo, Ernestina Tetteh, Lillian L Siu, Amita Patnaik, Kyriakos P Papadopoulos, Johann S de Bono, Anthony W Tolcher, Susan Minton

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Homoharringtonine and omacetaxine for myeloid hematological malignancies

Shuqing Lü, Jianmin Wang

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

Hiroaki Asai, Hiroshi Fujiwara, Sohei Kitazawa, Naoto Kobayashi, Toshiki Ochi, Yukihiro Miyazaki, Fumihiro Ochi, Yoshiki Akatsuka, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroaki Ikeda, Hiroshi Shiku, Masaki Yasukawa

01.12.2014 | Rapid communication | Ausgabe 1/2014 Open Access

Differentially expressed microRNAs in the serum of cervical squamous cell carcinoma patients before and after surgery

Wen-Tao Wang, Ya-Nan Zhao, Jin-Xing Yan, Mei-Ying Weng, Yan Wang, Yue-Qin Chen, Shun-Jia Hong

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery

Mingli Yang, Guohua Jiang, Wenjing Li, Kai Qiu, Min Zhang, Christopher M Carter, Samer Z Al-Quran, Ying Li

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

Denise Niewerth, Gertjan JL Kaspers, Yehuda G Assaraf, Johan van Meerloo, Christopher J Kirk, Janet Anderl, Jonathan L Blank, Peter M van de Ven, Sonja Zweegman, Gerrit Jansen, Jacqueline Cloos

01.12.2014 | Short report | Ausgabe 1/2014 Open Access

Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein

Vivek Subbiah, Shannon N Westin, Kai Wang, Dejka Araujo, Wei-Lien Wang, Vincent A Miller, Jeffrey S Ross, Phillip J Stephens, Gary A Palmer, Siraj M Ali

01.12.2014 | Case report | Ausgabe 1/2014 Open Access

Short-term efficacy of the IL6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease: report of two cases

Azusa Nagao, Shoko Nakazawa, Hideji Hanabusa

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels

Amy Guillaumet-Adkins, Julia Richter, Maria D Odero, Juan Sandoval, Xabi Agirre, Albert Catala, Manel Esteller, Felipe Prósper, María José Calasanz, Ismael Buño, Mi Kwon, Franck Court, Reiner Siebert, David Monk

01.12.2014 | Reviewer acknowledgement | Ausgabe 1/2014 Open Access

Journal of Hematology & Oncology reviewer acknowledgement 2013

Delong Liu

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Signaling pathways in the development of infantile hemangioma

Yi Ji, Siyuan Chen, Kai Li, Li Li, Chang Xu, Bo Xiang

01.12.2014 | Review | Ausgabe 1/2014 Open Access

The roles of mesenchymal stem cells in tumor inflammatory microenvironment

Zhao Sun, Shihua Wang, Robert Chunhua Zhao

01.12.2014 | Research | Ausgabe 1/2014 Open Access

A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma

Jianping Yuan, Satoshi Kashiwagi, Patrick Reeves, Jean Nezivar, Yuan Yang, Nadiah Hashim Arrifin, Mai Nguyen, Gilberte Jean-Mary, Xiaoyun Tong, Paramjit Uppal, Svetlana Korochkina, Ben Forbes, Tao Chen, Elda Righi, Roderick Bronson, Huabiao Chen, Sandra Orsulic, Timothy Brauns, Pierre Leblanc, Nathalie Scholler, Glenn Dranoff, Jeffrey Gelfand, Mark C Poznansky

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish

Zhi-Wei Dong, Chun-Guang Ren, Yu Xia, Dan Su, Ting-Ting Du, Hong-Bo Fan, Hao Yuan, Lei Wang, Mei Dong, Wei-Chun Li, Yi Jin, Yi Chen, Min Deng, Ting-Xi Liu, Ai-Hua Gu, Yong Zhou

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions

Fei Guo, Brittany C Parker Kerrigan, Da Yang, Limei Hu, Ilya Shmulevich, Anil K Sood, Fengxia Xue, Wei Zhang

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Long-term results of a phase II study with neoadjuvant docetaxel chemotherapy and complete androgen blockade in locally advanced and high-risk prostate cancer

Mark Thalgott, Thomas Horn, Matthias M Heck, Tobias Maurer, Matthias Eiber, Margitta Retz, Michael Autenrieth, Kathleen Herkommer, Bernd J Krause, Jürgen E Gschwend, Uwe Treiber, Hubert R Kübler

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies

Raoul Tibes, Ruben A Mesa

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis

Samir Al Bashir, Mohammed Alshalalfa, Samar A Hegazy, Michael Dolph, Bryan Donnelly, Tarek A Bismar

01.12.2014 | Research | Ausgabe 1/2014 Open Access

CD44 standard and CD44v10 isoform expression on leukemia cells distinctly influences niche embedding of hematopoietic stem cells

Ulrike Erb, Amelie Pajip Megaptche, Xiaoyu Gu, Markus W Büchler, Margot Zöller

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation

Zoya Gluzman-Poltorak, Sarita R Mendonca, Vladimir Vainstein, Hue Kha, Lena A Basile

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma

Lu Dai, Yueyu Cao, Yihan Chen, Chris Parsons, Zhiqiang Qin

01.12.2014 | Research | Ausgabe 1/2014 Open Access

A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies

Caroline S Breton, Aimable Nahimana, Dominique Aubry, Julie Macoin, Pierre Moretti, Martin Bertschinger, Samuel Hou, Michel A Duchosal, Jonathan Back

01.12.2014 | Case report | Ausgabe 1/2014 Open Access

Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia

Shilpan Shah, Sanam Loghavi, Guillermo Garcia-Manero, Joseph D Khoury

01.12.2014 | Short report | Ausgabe 1/2014 Open Access

Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

David J Araten, Anna Paola Iori, Karen Brown, Giovanni Fernando Torelli, Walter Barberi, Fiammetta Natalino, Maria Stefania De Propris, Corrado Girmenia, Filippo Maria Salvatori, Orly Zelig, Robin Foà, Lucio Luzzatto

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse model

Ke-Zhi Zhang, Qiang-Bo Zhang, Quan-Bao Zhang, Hui-Chuan Sun, Jian-Yang Ao, Zong-Tao Chai, Xiao-Dong Zhu, Lu Lu, Yuan-Yuan Zhang, Yang Bu, Ling-Qun Kong, Zhao-You Tang

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Retreatment with brentuximab vedotin in patients with CD30-positive hematologic malignancies

Nancy L Bartlett, Robert Chen, Michelle A Fanale, Pauline Brice, Ajay Gopal, Scott E Smith, Ranjana Advani, Jeffrey V Matous, Radhakrishnan Ramchandren, Joseph D Rosenblatt, Dirk Huebner, Pamela Levine, Laurie Grove, Andres Forero-Torres

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice

Kaiyao Shi, Wanke Zhao, Yun Chen, Wanting Tina Ho, Ping Yang, Zhizhuang Joe Zhao

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Structural determinants of human ζ-globin mRNA stability

Zhenning He, Decheng Song, Sebastiaan van Zalen, J Eric Russell

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

Catarina Lundin, Erik Forestier, Mette Klarskov Andersen, Kirsi Autio, Gisela Barbany, Lucia Cavelier, Irina Golovleva, Sverre Heim, Kristiina Heinonen, Randi Hovland, Johann H Johannsson, Eigil Kjeldsen, Ann Nordgren, Lars Palmqvist, Bertil Johansson, the Swedish Cytogenetic Leukemia Study Group (SCLSG), the NOPHO Leukemia Cytogenetic Study Group (NLCSG)

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

The addition of rituximab to CHOP therapy alters the prognostic significance of CD44 expression

Xiaolei Wei, Meng Xu, Yongqiang Wei, Fen Huang, Tong Zhao, Xiangzhao Li, Ru Feng, B Hilda Ye

01.12.2014 | Case report | Ausgabe 1/2014 Open Access

Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature

Juehua Gao, Ryan D Gentzler, Andrew E Timms, Marshall S Horwitz, Olga Frankfurt, Jessica K Altman, LoAnn C Peterson

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Combination of the ABL kinase inhibitor imatinib with the Janus kinase 2 inhibitor TG101348 for targeting residual BCR-ABL-positive cells

Seiichi Okabe, Tetsuzo Tauchi, Seiichiro Katagiri, Yuko Tanaka, Kazuma Ohyashiki

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

Antibodies reacting with Simian Virus 40 capsid protein mimotopes in serum samples from patients affected by uveal melanoma

Ilaria Bononi, Paolo Perri, Alice Begnardi, Alessandra Martini, Elisa Mazzoni, Silvia Bosi, Silvia Pietrobon, Adolfo Sebastiani, Mauro Tognon, Fernanda Martini

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Argonaute 2 promotes myeloma angiogenesis via microRNA dysregulation

Shuang Wu, Wenjun Yu, Xiaoyan Qu, Rong Wang, Ji Xu, Qiguo Zhang, Jiaren Xu, Jianyong Li, Lijuan Chen

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells

Yi Yu, Mingxing Zhang, Xiaoyan Zhang, Qingqing Cai, Shanshan Hong, Wei Jiang, Congjian Xu

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study

M Kay Garcia, Lorenzo Cohen, Ying Guo, Yuhong Zhou, Bing You, Joseph Chiang, Robert Z Orlowski, Donna Weber, Jatin Shah, Raymond Alexanian, Sheeba Thomas, Jorge Romaguera, Liang Zhang, Maria Badillo, Yiming Chen, Qi Wei, Richard Lee, Kay Delasalle, Vivian Green, Michael Wang

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Identification of nuclear-enriched miRNAs during mouse granulopoiesis

Justin JL Wong, William Ritchie, Dadi Gao, Katherine A Lau, Maria Gonzalez, Anupma Choudhary, Ryan J Taft, John EJ Rasko, Jeff Holst

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding

Agnieszka Dzikiewicz-Krawczyk, Anna Macieja, Ewa Mały, Danuta Januszkiewicz-Lewandowska, Maria Mosor, Marta Fichna, Ewa Strauss, Jerzy Nowak

01.12.2014 | Short report | Ausgabe 1/2014 Open Access

IMP3 signatures of fallopian tube: a risk for pelvic serous cancers

Yiying Wang, Yue Wang, Dake Li, Lingmin Li, Wenjing Zhang, Guang Yao, Zhong Jiang, Wenxin Zheng

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients

Isabelle Bartram, Nicola Gökbuget, Cornelia Schlee, Sandra Heesch, Lars Fransecky, Stefan Schwartz, Reingard Stuhlmann, Kerstin Schäfer-Eckhart, Michael Starck, Albrecht Reichle, Dieter Hoelzer, Claudia D Baldus, Martin Neumann

01.12.2014 | Research | Ausgabe 1/2014 Open Access

High frequency of TERT promoter mutation in small cell carcinoma of bladder, but not in small cell carcinoma of other origins

Xiaoyong Zheng, Jian Zhuge, Stephania M Bezerra, Sheila F Faraj, Enrico Munari, John T Fallon, Ximing J Yang, Pedram Argani, George J Netto, Minghao Zhong

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Advances in understanding the cell types and approaches used for generating induced pluripotent stem cells

Jun Li, Wei Song, Guangjin Pan, Jun Zhou

01.12.2014 | Research | Ausgabe 1/2014 Open Access

CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells

Wenxiu Qi, Chengzhi Xie, Chunhuai Li, J Timothy Caldwell, Holly Edwards, Jeffrey W Taub, Yue Wang, Hai Lin, Yubin Ge

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Toll-like receptors in the pathogenesis of human B cell malignancies

Johana M Isaza-Correa, Zheng Liang, Anke van den Berg, Arjan Diepstra, Lydia Visser

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial

Vivek Subbiah, Funda Meric-Bernstam, Gordon B Mills, Kenna R Mills Shaw, Ann Marie Bailey, Priya Rao, John F Ward, Lance C Pagliaro

01.12.2014 | Review | Ausgabe 1/2014 Open Access

The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation

Limengmeng Wang, Haowen Xiao, Xing Zhang, Chong Wang, He Huang

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair

Qin Qin, Hongyan Cheng, Jing Lu, Liangliang Zhan, Jianchao Zheng, Jing Cai, Xi Yang, Liping Xu, Hongcheng Zhu, Chi Zhang, Jia Liu, Jianxin Ma, Xizhi Zhang, Shengbin Dai, Xinchen Sun

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression

Tong-peng Xu, Ming-de Huang, Rui Xia, Xin-xin Liu, Ming Sun, Li Yin, Wen-ming Chen, Liang Han, Er-bao Zhang, Rong Kong, Wei De, Yong-qian Shu

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Multicenter phase ii study of a combination of cyclosporine a, methotrexate and mycophenolate mofetil for GVHD prophylaxis: results of the Chinese Bone Marrow Transplant Cooperative Group (CBMTCG)

Yong-rong Lai, Yu-hong Chen, Deng-ming Hu, Ming Jiang, Qi-fa Liu, Lin Liu, Jian Hou, Paul Schwarzenberger, Qiao-chuan Li, Zhong-ming Zhang, Kai-yan Liu, Xiao-jun Huang

01.12.2014 | Review | Ausgabe 1/2014 Open Access

New antibody approaches to lymphoma therapy

Tejas Suresh, Lisa X Lee, Jitesh Joshi, Stefan K Barta

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes

Shanique KE Edwards, Jacqueline Baron, Carissa R Moore, Yan Liu, David H Perlman, Ronald P Hart, Ping Xie

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Long-term follow-up of cytogenetically normal CEBPA-mutated AML

Friederike Pastore, Daniela Kling, Eva Hoster, Annika Dufour, Nikola P Konstandin, Stephanie Schneider, Maria C Sauerland, Wolfgang E Berdel, Thomas Buechner, Bernhard Woermann, Jan Braess, Wolfgang Hiddemann, Karsten Spiekermann

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL

Alexandra Aronin, Shira Amsili, Tatyana B Prigozhina, Kobi Tzdaka, Roy Shen, Leonid Grinmann, Fanny Szafer, Per Edebrink, Mari-Anne Rauvola, Noam Shani, Michal Dranitzki Elhalel

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

8q24 amplified segments involve novel fusion genes between NSMCE2 and long noncoding RNAs in acute myelogenous leukemia

Yoshiaki Chinen, Natsumi Sakamoto, Hisao Nagoshi, Tomohiko Taki, Saori Maegawa, Shotaro Tatekawa, Taku Tsukamoto, Shinsuke Mizutani, Yuji Shimura, Mio Yamamoto-Sugitani, Tsutomu Kobayashi, Yosuke Matsumoto, Shigeo Horiike, Junya Kuroda, Masafumi Taniwaki

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

CEBPA-regulated lncRNAs, new players in the study of acute myeloid leukemia

James M Hughes, Beatrice Salvatori, Federico M Giorgi, Irene Bozzoni, Alessandro Fatica

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Lower circulating platelet counts and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma

Saleh Rachidi, Kristin Wallace, Terry A Day, Anthony J Alberg, Zihai Li

01.12.2014 | Short report | Ausgabe 1/2014 Open Access

CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia

Hana Hájková, Markus Hsi-Yang Fritz, Cedrik Haškovec, Jiří Schwarz, Cyril Šálek, Jana Marková, Zdeněk Krejčík, Michaela Dostálová Merkerová, Arnošt Kostečka, Martin Vostrý, Ota Fuchs, Kyra Michalová, Petr Cetkovský, Vladimír Beneš

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation

Li Zhang, Qiu-Sheng Chen, Peng-Peng Xu, Ying Qian, Ai-Hua Wang, Dan Xiao, Yan Zhao, Yan Sheng, Xiang-Qin Wen, Wei-Li Zhao

01.12.2014 | Review | Ausgabe 1/2014 Open Access

T cell immune abnormalities in immune thrombocytopenia

Xuebin Ji, Liping Zhang, Jun Peng, Ming Hou

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Strategies for modern biomarker and drug development in oncology

Alan D Smith, Desam Roda, Timothy A Yap

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Clinical features of De Novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations

Sanam Loghavi, Zhuang Zuo, Farhad Ravandi, Hagop M Kantarjian, Carlos Bueso-Ramos, Liping Zhang, Rajesh R Singh, Keyur P Patel, L Jeffrey Medeiros, Francesco Stingo, Mark Routbort, Jorge Cortes, Rajyalakshmi Luthra, Joseph D Khoury

01.12.2014 | Editorial | Ausgabe 1/2014 Open Access

SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents

John Gerecitano

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma

Jilong Yang, Matti Annala, Ping Ji, Guowen Wang, Hong Zheng, David Codgell, Xiaoling Du, Zhiwei Fang, Baocun Sun, Matti Nykter, Kexin Chen, Wei Zhang

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents

Kaushal Parikh, Shundong Cang, Arunabh Sekhri, Delong Liu

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia

Yajuan Cui, Bing Li, Robert Peter Gale, Qian Jiang, Zefeng Xu, Tiejun Qin, Peihong Zhang, Yue Zhang, Zhijian Xiao

01.12.2014 | Research | Ausgabe 1/2014 Open Access

DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells

Qian Chu, Na Han, Xun Yuan, Xin Nie, Hua Wu, Yu Chen, Mingzhou Guo, Shiying Yu, Kongming Wu

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

Potential therapeutic role of antagomiR17 for the treatment of chronic lymphocytic leukemia

Sara Dereani, Paolo Macor, Tiziana D’Agaro, Nelly Mezzaroba, Michele Dal-Bo, Sara Capolla, Antonella Zucchetto, Erika Tissino, Giovanni Del Poeta, Sonia Zorzet, Valter Gattei, Riccardo Bomben

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction- a novel mechanism for maintaining vascular function

Ying Shao, Zhongjian Cheng, Xinyuan Li, Valeria Chernaya, Hong Wang, Xiao-feng Yang

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen

Shihui Ma, Yingxu Shi, Yakun Pang, Fang Dong, Hui Cheng, Sha Hao, Jing Xu, Xiaofan Zhu, Weiping Yuan, Tao Cheng, Guoguang Zheng

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

Constitutional and somatic deletions of the Williams-Beuren syndrome critical region in Non-Hodgkin Lymphoma

David Guenat, Samuel Quentin, Carmelo Rizzari, Catarina Lundin, Tiziana Coliva, Patrick Edery, Helen Fryssira, Laurent Bermont, Christophe Ferrand, Jean Soulier, Christophe Borg, Pierre-Simon Rohrlich

01.12.2014 | Research highlight | Ausgabe 1/2014 Open Access

SWI/SNF proteins as targets in cancer therapy

Santiago Schiaffino-Ortega, Carlos Balinas, Marta Cuadros, Pedro P Medina

01.12.2014 | Review | Ausgabe 1/2014 Open Access

MicroRNA-binding site polymorphisms in hematological malignancies

Agnieszka Dzikiewicz-Krawczyk

01.12.2014 | Research highlight | Ausgabe 1/2014 Open Access

MicroRNA-mediated regulation of KRAS in cancer

Minlee Kim, Frank J Slack

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Nucleo-cytoplasmic transport as a therapeutic target of cancer

Giovanni Luca Gravina, William Senapedis, Dilara McCauley, Erkan Baloglu, Sharon Shacham, Claudio Festuccia

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Circulating miRNAs in cancer: from detection to therapy

Wen-Tao Wang, Yue-Qin Chen

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

Xun Yuan, Hua Wu, Na Han, Hanxiao Xu, Qian Chu, Shiying Yu, Yuan Chen, Kongming Wu

01.12.2014 | Research | Ausgabe 1/2014 Open Access

c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors

Zhong Zheng, Shu Cheng, Wen Wu, Li Wang, Yan Zhao, Yang Shen, Anne Janin, Wei-Li Zhao

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts

Valeria Visconte, Ali Tabarroki, Li Zhang, Yvonne Parker, Edy Hasrouni, Reda Mahfouz, Kyoichi Isono, Haruhiko Koseki, Mikkael A Sekeres, Yogen Saunthararajah, John Barnard, Daniel Lindner, Heesun J Rogers, Ramon V Tiu

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Pim kinases in hematological malignancies: where are we now and where are we going?

Patrizia Mondello, Salvatore Cuzzocrea, Michael Mian

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Functions of lncRNA HOTAIR in lung cancer

Gregory Loewen, Janarthanan Jayawickramarajah, Ying Zhuo, Bin Shan

01.12.2014 | Review | Ausgabe 1/2014 Open Access

Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia

Bing Li, Robert Peter Gale, Zhijian Xiao

01.12.2014 | Letter to the Editor | Ausgabe 1/2014 Open Access

Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms

Rebekka K Schneider, Susanne Ziegler, Isabelle Leisten, Monica SV Ferreira, Anne Schumacher, Björn Rath, Dirk Fahrenkamp, Gerhard Müller-Newen, Martina Crysandt, Stefan Wilop, Edgar Jost, Steffen Koschmieder, Ruth Knüchel, Tim H Brümmendorf, Patrick Ziegler

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma

Debra Ehrlich, Bo Wang, Wei Lu, Peter Dowling, Ruirong Yuan

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations

Karolina Skvarova Kramarzova, Karel Fiser, Ester Mejstrikova, Katerina Rejlova, Marketa Zaliova, Maarten Fornerod, Harry A Drabkin, Marry M van den Heuvel-Eibrink, Jan Stary, Jan Trka, Julia Starkova

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms

Maria Braoudaki, George I Lambrou, Krinio Giannikou, Vasilis Milionis, Kalliopi Stefanaki, Diane K Birks, Neophytos Prodromou, Aggeliki Kolialexi, Antonis Kattamis, Chara A Spiliopoulou, Fotini Tzortzatou-Stathopoulou, Emmanouel Kanavakis

01.12.2014 | Research | Ausgabe 1/2014 Open Access

XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa)

Giovanni Luca Gravina, Monica Tortoreto, Andrea Mancini, Alessandro Addis, Ernesto Di Cesare, Andrea Lenzi, Yosef Landesman, Dilara McCauley, Michael Kauffman, Sharon Shacham, Nadia Zaffaroni, Claudio Festuccia

01.12.2014 | Research | Ausgabe 1/2014 Open Access

A phase II study of dacetuzumab (SGN-40) in patients with relapsed diffuse large B-cell lymphoma (DLBCL) and correlative analyses of patient-specific factors

Sven de Vos, Andres Forero-Torres, Stephen M Ansell, Brad Kahl, Bruce D Cheson, Nancy L Bartlett, Richard R Furman, Jane N Winter, Henry Kaplan, John Timmerman, Nancy C Whiting, Jonathan G Drachman, Ranjana Advani

01.12.2014 | Research | Ausgabe 1/2014 Open Access

The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease

Karin Gustafsson, Maria Jamalpour, Camilla Trinh, Michael G Kharas, Michael Welsh

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization

Kunkun Han, Xin Xu, Guodong Chen, Yuanying Zeng, Jingyu Zhu, Xiaolin Du, Zubin Zhang, Biyin Cao, Zhaopeng Liu, Xinliang Mao

01.12.2014 | Research | Ausgabe 1/2014 Open Access

Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses

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01.12.2014 | Research | Ausgabe 1/2014 Open Access

Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation

Katarzyna A Darlak, Ying Wang, Jian-Ming Li, Wayne AC Harris, Cynthia R Giver, Chunzi Huang, Edmund K Waller

01.12.2014 | Research | Ausgabe 1/2014 Open Access

A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors

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01.12.2014 | Research | Ausgabe 1/2014 Open Access

ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells

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01.12.2014 | Research | Ausgabe 1/2014 Open Access

The mutation profile of JAK2 and CALR in Chinese Han patients with Philadelphia chromosome-negative myeloproliferative neoplasms

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01.12.2014 | Review | Ausgabe 1/2014 Open Access

Tissue factor in tumor microenvironment: a systematic review

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