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01.01.2013 | Clinical Research

Improvement in Cardiovascular Indices After Roux-en-Y Gastric Bypass or Sleeve Gastrectomy for Morbid Obesity

verfasst von: Alexander Kokkinos, Kleopatra Alexiadou, Christos Liaskos, Georgia Argyrakopoulou, Ioanna Balla, Nicholas Tentolouris, Ioannis Moyssakis, Nicholas Katsilambros, Irene Vafiadis, Andreas Alexandrou, Theodoros Diamantis

Erschienen in: Obesity Surgery | Ausgabe 1/2013

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Abstract

Background

Morbidly obese patients display cardiac abnormalities which are partially reversed after weight loss. The aim of the present study was to assess the potential difference in cardiovascular disease indices between patients who underwent either gastric bypass surgery or sleeve gastrectomy.

Methods

Thirty-seven morbidly obese patients who underwent either Roux-en-Y gastric bypass (RYGB) (n = 14) or SG (n = 23) were examined before, 3 and 6 months after surgery. Indices of cardiac autonomic nervous system activity were evaluated, namely baroreflex sensitivity (BRS) and heart rate variability (HRV). A complete echocardiographic study was performed in a subgroup of 17 patients (RYGB 8, SG 9) preoperatively and 6 months after surgery, evaluating epicardial fat thickness, aortic distensibility, left ventricular (LV) Tei index, left atrium diameter, ejection fraction, and LV mass.

Results

All subjects experienced significant (p < 0.001) and similar weight loss independently of the type of operation. BRS and HRV indices improved significantly and to the same degree after surgery in both groups. In the echocardiographic study, all parameters improved significantly at 6 months in comparison with the baseline values. In addition, the RYGB group displayed significantly greater reduction in epicardial fat thickness (p = 0.007) and also tended to have a better LV performance as expressed by the lower values of the Tei index (p = 0.06) compared to the SG group 6 months after surgery.

Conclusions

Both RYGB and SG exert comparable effects on weight loss and improvement of cardiovascular parameters. RYGB displays a more beneficial influence on epicardial fat thickness and left ventricular performance than SG.

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Titel: Improvement in Cardiovascular Indices After Roux-en-Y Gastric Bypass or Sleeve Gastrectomy for Morbid Obesity
verfasst von: Alexander Kokkinos
Kleopatra Alexiadou
Christos Liaskos
Georgia Argyrakopoulou
Ioanna Balla
Nicholas Tentolouris
Ioannis Moyssakis
Nicholas Katsilambros
Irene Vafiadis
Andreas Alexandrou
Theodoros Diamantis
Publikationsdatum: 01.01.2013
Verlag: Springer-Verlag
Erschienen in: Obesity Surgery / Ausgabe 1/2013
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-012-0743-8

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Improvement in Cardiovascular Indices After Roux-en-Y Gastric Bypass or Sleeve Gastrectomy for Morbid Obesity