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Current Neurology and Neuroscience Reports

Erschienen in:

01.11.2020 | COVID-19 | Neurology of Systemic Disease (J Biller, Section Editor) Zur Zeit gratis

Central Nervous System Manifestations Associated with COVID-19

verfasst von: Afshin A. Divani, Sasan Andalib, José Biller, Mario Di Napoli, Narges Moghimi, Clio A. Rubinos, Christa O’Hana Nobleza, P. N Sylaja, Michel Toledano, Simona Lattanzi, Louise D McCullough, Salvador Cruz-Flores, Michel Torbey, M. Reza Azarpazhooh

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 12/2020

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Abstract

Purpose of Review

Coronavirus disease 2019 (COVID-19) has become a global health crisis of our time. The disease arises from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that binds to angiotensin-converting enzyme 2 (ACE2) receptors on host cells for its internalization. COVID-19 has a wide range of respiratory symptoms from mild to severe and affects several other organs, increasing the complexity of the treatment. There is accumulating evidence to suggest that SARS-CoV-2 can target the nervous system. In this review, we provide an account of the COVID-19 central nervous system (CNS) manifestations.

Recent Findings

A broad spectrum of the CNS manifestations including headache, impaired consciousness, delirium, loss of smell and taste, encephalitis, seizures, strokes, myelitis, acute disseminated encephalomyelitis, neurogenic respiratory failure, encephalopathy, silent hypoxemia, generalized myoclonus, neuroleptic malignant syndrome and Kawasaki syndrome has been reported in patients with COVID-19.

Summary

CNS manifestations associated with COVID-19 should be considered in clinical practice. There is a need for modification of current protocols and standing orders to provide better care for COVID-19 patients presenting with neurological symptoms.

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Titel: Central Nervous System Manifestations Associated with COVID-19
verfasst von: Afshin A. Divani
Sasan Andalib
José Biller
Mario Di Napoli
Narges Moghimi
Clio A. Rubinos
Christa O’Hana Nobleza
P. N Sylaja
Michel Toledano
Simona Lattanzi
Louise D McCullough
Salvador Cruz-Flores
Michel Torbey
M. Reza Azarpazhooh
Publikationsdatum: 01.11.2020
Verlag: Springer US
Schlagwörter: COVID-19
Meningitis
Enzephalitis
Neurologische Beteiligung bei Infektionserkrankungen
Kopfschmerzsyndrome
Kopfschmerzen
Leitsymptom Kopfschmerz
Nicht epileptische Anfälle
Apoplex
Delir
Erschienen in: Current Neurology and Neuroscience Reports / Ausgabe 12/2020
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-020-01079-7

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