nach oben

Head and Neck Pathology

Erschienen in:

01.03.2016 | Special Issue: Sinonasal Tract Pathology. Guest Editors: Justin Bishop, MD and Alessandro Franchi, MD

Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma

verfasst von: Ketan Shah, Bayardo Perez-Ordóñez

Erschienen in: Head and Neck Pathology | Ausgabe 1/2016

Einloggen, um Zugang zu erhalten

Abstract

Neuroendocrine neoplasms (NENs) can occur in organs or tissues that do not contain neuroendocrine cells normally and do not necessarily imply embryologic derivation from the neuroectoderm; but rather reflect a shared phenotype characterized by the expression of multiple genes encoding both endocrine and neuronal features. NENs are rare in the sinonasal tract and are subdivided into epithelial and neural subtypes based on the presence of keratins or neurofilaments, respectively. Although relatively rare, neuroendocrine carcinomas (NECs) and olfactory neuroblastoma (ONB) are the most common neuroendocrine neoplasms of the sinonasal tract. The focus of this review is to highlight recent developments in the pathology of sinonasal NECs and ONB in light of the upcoming update of the World Health Organization (WHO) 2005 classification of tumors of the head and neck.

Mills SE. Neuroectodermal neoplasms of the head and neck with emphasis on neuroendocrine carcinomas. Mod Pathol. 2002;15:264–78.CrossRefPubMed

DeLellis RA. The neuroendocrine system and its tumors: an overview. Am J Clin Pathol. 2001;115(Suppl):S5–16.PubMed

World Health Organization Classification of Tumours. Pathology and genetics head and neck. Lyon: IARC Press; 2005.

Wenig BM, Gnepp DR. The spectrum of neuroendocrine carcinomas of the larynx. Semin Diagn Pathol. 1989;6:329–50.PubMed

Kusafuka K, Ferlito A, Lewis JS Jr, et al. Large cell neuroendocrine carcinoma of the head and neck. Oral Oncol. 2012;48:211–5.CrossRefPubMed

Kao HL, Chang WC, Li WY, et al. Head and neck large cell neuroendocrine carcinoma should be separated from atypical carcinoid on the basis of different clinical features, overall survival, and pathogenesis. Am J Surg Pathol. 2012;36:185–92.CrossRefPubMed

Xu B, Chetty R, Perez-Ordonez B. Neuroendocrine neoplasms of the head and neck: some suggestions for the new WHO classification of head and neck tumors. Head Neck Pathol. 2014;8:24–32.PubMedCentralCrossRefPubMed

Bell D, Hanna EY, Weber RS, et al. Neuroendocrine neoplasms of the sinonasal region. Head Neck. 2015; PM:26041714.

Renner G. Small cell carcinoma of the head and neck: a review. Semin Oncol. 2007;34:3–14.CrossRefPubMed

10.

Su SY, Bell D, Hanna EY. Esthesioneuroblastoma, neuroendocrine carcinoma, and sinonasal undifferentiated carcinoma: differentiation in diagnosis and treatment. Int Arch Otorhinolaryngol. 2014;18:S149–56.PubMedCentralCrossRefPubMed

11.

Kayakabe M, Takahashi K, Okamiya T, et al. Combined small cell carcinoma of the sinonasal tract associated with syndrome of inappropriate secretion of antidiuretic hormone: a case report. Oncol Lett. 2014;7:1253–6.PubMedCentralPubMed

12.

Ma ATW, Lei KIK. Small cell neuroendocrine carcinoma of the ethmoid sinuses presenting with generalized seizure and syndrome of inappropriate antidiuretic hormone secretion: a case report and review of the literature. Am J Otolaryngol. 2009;30:54–7.CrossRefPubMed

13.

Chu MW, Karakla DW, Silverberg M, et al. Primary carcinoid tumor of the frontal sinus: a case report. Ear Nose Throat J. 2010;89:E13–6.PubMed

14.

Mills SE, Stelow EB, Hunt JL. Neural, neuroendocrine, and neuroectoderma neoplasia. In: Steven G, Silverberg, MD, editors. Tumors of the upper aerodigestive tract and ear. Silver Spring: American Registry of Pathology; 2012. p. 173–260.

15.

Siwersson U, Kindblom LG. Oncocytic carcinoid of the nasal cavity and carcinoid of the lung in a child. Pathol Res Pract. 1984;178:562–9.CrossRefPubMed

16.

Furuta A, Kudo M, Kanai K, et al. Typical carcinoid tumor arising in the nose and paranasal sinuses—case report. Auris Nasus Larynx. 2010;37:381–5.CrossRefPubMed

17.

Galm T, Turner N. Primary carcinoid tumour of nasal septum. J Laryngol Otol. 2009;123:789–92.CrossRefPubMed

18.

Likhacheva A, Rosenthal DI, Hanna E, et al. Sinonasal neuroendocrine carcinoma: impact of differentiation status on response and outcome. Head Neck Oncol. 2011;3:32.PubMedCentralCrossRefPubMed

19.

Hafezi S, Seethala RR, Stelow EB, et al. Ewing’s family of tumors of the sinonasal tract and maxillary bone. Head Neck Pathol. 2011;5:8–16.PubMedCentralCrossRefPubMed

20.

French CA. The importance of diagnosing NUT midline carcinoma. Head Neck Pathol. 2013;7:11–6.PubMedCentralCrossRefPubMed

21.

Laco J, Sieglova K, Vosmikova H, et al. The presence of high-risk human papillomavirus (HPV) E6/E7 mRNA transcripts in a subset of sinonasal carcinomas is evidence of involvement of HPV in its etiopathogenesis. Virchows Arch. 2015;467:404–15.CrossRef

22.

Bishop JA, Guo TW, Smith DF, et al. Human papillomavirus-related carcinomas of the sinonasal tract. Am J Surg Pathol. 2013;37:185–92.PubMedCentralCrossRefPubMed

23.

Travis WD, Linnoila RI, Tsokos MG, et al. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases. Am J Surg Pathol. 1991;15:529–53.CrossRefPubMed

24.

Berger L, Luc G, Richard D. L’esthésioneuroépithéliome olfactif. Bull Assoc Fr Etud Cancer. 1924;13:410–21.

25.

Jethanamest D, Morris LG, Sikora AG, et al. Esthesioneuroblastoma: a population-based analysis of survival and prognostic factors. Arch Otolaryngol Head Neck Surg. 2007;133:276–80.CrossRefPubMed

26.

Bell D, Saade R, Roberts D, et al. Prognostic utility of Hyams histological grading and Kadish–Morita staging systems for esthesioneuroblastoma outcomes. Head Neck Pathol. 2015;9:51–9.PubMedCentralCrossRefPubMed

27.

Mintzer DM, Zheng S, Nagamine M, et al. Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital. Oncologist. 2010;15:51–8.PubMedCentralCrossRefPubMed

28.

Myers SL, Hardy DA, Weibe CB, et al. Olfactory neuroblastoma invading the oral cavity in a patient with inappropriate antidiuretic hormone secretion. Oral Surg Oral Med Oral Pathol. 1994;77:645–50.CrossRefPubMed

29.

Kadish S, Goodman M, Wang CC. Olfactory neuroblastoma. A clinical analysis of 17 cases. Cancer. 1976;37:1571–6.CrossRefPubMed

30.

Morita A, Ebersold MJ, Olsen KD, et al. Esthesioneuroblastoma: prognosis and management. Neurosurgery. 1993;32:706–14.CrossRefPubMed

31.

Dulguerov P, Allal AS, Calcaterra TC. Esthesioneuroblastoma: a meta-analysis and review. Lancet Oncol. 2001;2:683–90.CrossRefPubMed

32.

Miller DC, Goodman ML, Pilch BZ, et al. Mixed olfactory neuroblastoma and carcinoma. A report of two cases. Cancer. 1984;54:2019–28.CrossRefPubMed

33.

Bates T, Plessis DD, Polvikoski T, et al. Ganglioneuroblastic transformation in olfactory neuroblastoma. Head Neck Pathol. 2012;6:150–5.PubMedCentralCrossRefPubMed

34.

Wooff JC, Weinreb I, Perez-Ordonez B, et al. Calretinin staining facilitates differentiation of olfactory neuroblastoma from other small round blue cell tumors in the sinonasal tract. Am J Surg Pathol. 2011;35:1786–93.CrossRefPubMed

35.

Argani P, Perez-Ordonez B, Xiao H, et al. Olfactory neuroblastoma is not related to the Ewing family of tumors. Absence of EWS/FLI1 gene fusion and MIC2 expression. Am J Surg Pathol. 1998;22:391–8.CrossRefPubMed

36.

Weiss GJ, Liang WS, Izatt T, et al. Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma. PLoS ONE. 2012;7:e37029.PubMedCentralCrossRefPubMed

37.

Guled M, Myllykangas S, Frierson HF Jr, et al. Array comparative genomic hybridization analysis of olfactory neuroblastoma. Mod Pathol. 2008;21:770–8.CrossRefPubMed

38.

Rimmer J, Lund VJ, Beale T, et al. Olfactory neuroblastoma: a 35-year experience and suggested follow-up protocol. Laryngoscope. 2014;124:1542–9.CrossRefPubMed

39.

Van Gompel JJ, Giannini C, Olsen KD, et al. Long-term outcome of esthesioneuroblastoma: Hyams grade predicts patient survival. J Neurol Surg B Skull Base. 2012;73:331–6.PubMedCentralCrossRefPubMed

40.

Hyams VJ, Batsakis JG, Michaels L. Neuroectodermal lesions. In: Hyams VJ, Batsakis JG, Michaels L, editors. Tumors of the upper respiratory tract and ear. Washington: AFIP; 1988. p. 226–57.

Titel: Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma
verfasst von: Ketan Shah
Bayardo Perez-Ordóñez
Publikationsdatum: 01.03.2016
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2016
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-016-0696-7

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Neuroendocrine Neoplasms of the Sinonasal Tract: Neuroendocrine Carcinomas and Olfactory Neuroblastoma

Abstract

Neu im Fachgebiet Pathologie

Assistierter Suizid durch Infusion von Thiopental

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2016

Pathology of Fungal Rhinosinusitis: A Review

Non-infectious Inflammatory Lesions of the Sinonasal Tract

Newly Described Tumor Entities in Sinonasal Tract Pathology

An Update on Sinonasal Round Cell Undifferentiated Tumors

Hematolymphoid Lesions of the Sinonasal Tract

Endonasal Endoscopic Surgery in the Management of Sinonasal and Anterior Skull Base Malignancies

Neu im Fachgebiet Pathologie

Assistierter Suizid durch Infusion von Thiopental

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren